YU47076B - Postupak za izradu transdermalnog terapijskog sistema sa fizostigminom kao aktivnim sastojkom - Google Patents

Postupak za izradu transdermalnog terapijskog sistema sa fizostigminom kao aktivnim sastojkom

Info

Publication number
YU47076B
YU47076B YU240689A YU240689A YU47076B YU 47076 B YU47076 B YU 47076B YU 240689 A YU240689 A YU 240689A YU 240689 A YU240689 A YU 240689A YU 47076 B YU47076 B YU 47076B
Authority
YU
Yugoslavia
Prior art keywords
active ingredient
weight
therapeutic system
transdermal therapeutic
physostigmin
Prior art date
Application number
YU240689A
Other languages
English (en)
Other versions
YU240689A (en
Inventor
T. Hille
H.R. Hoffmann
H.J. Huber
A. Knock
G. Schneider
Original Assignee
Lts. Lohmann Therapie-Systeme Gmbh. & Co. Kg.
Klinge Pharma Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts. Lohmann Therapie-Systeme Gmbh. & Co. Kg., Klinge Pharma Gmbh. filed Critical Lts. Lohmann Therapie-Systeme Gmbh. & Co. Kg.
Priority to SI8912406A priority Critical patent/SI8912406B/sl
Publication of YU240689A publication Critical patent/YU240689A/xx
Priority to HRP-2406/89A priority patent/HRP930588B1/xx
Publication of YU47076B publication Critical patent/YU47076B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

POSTUPAK ZA IZRADU TRANSDERMALNOG TERAPIJSKOG SISTEMA SA FIZOSTIGMINOM KAO AKTIVNIM SASTOJKOM, koji sadrži pokrivni sloj nepropusan za aktivnu materiju, sloj rezervoara koji se lepi prianjajući u datom slučaju ponova odvojiv zaštitni sloj, naznačen time, što se na prethodno izradjen samolepljivi, u datom slučaju sa odvojivim zaštitnim slojem snabdeveni sloj matriksa postavlja tekstilna ravna tvorevina, na tekstilnu ravnu tvorevinu nanosi fizostigmin ili jedna od njegovih farmaceutski prihvatljivih soli u rastvoru uz stvaranje depoa aktivne materija, posle čega se matriks i depo aktivne materije snabdevaju sa pokrivnim slojem. Prijava sadrži još 1 nezavisan i 16 zavisnih zahteva.
YU240689A 1988-12-22 1989-12-19 Postupak za izradu transdermalnog terapijskog sistema sa fizostigminom kao aktivnim sastojkom YU47076B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI8912406A SI8912406B (sl) 1988-12-22 1989-12-19 Postopek za izdelavo transdermalnega terapevtskega sistema s fizostigminom kot dejavno sestavino
HRP-2406/89A HRP930588B1 (en) 1988-12-22 1993-03-29 Process for the preparation of therapeutic transdermal system having physostigmine as an active ingredient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3843238A DE3843238C1 (sh) 1988-12-22 1988-12-22

Publications (2)

Publication Number Publication Date
YU240689A YU240689A (en) 1991-04-30
YU47076B true YU47076B (sh) 1994-12-28

Family

ID=6369854

Family Applications (1)

Application Number Title Priority Date Filing Date
YU240689A YU47076B (sh) 1988-12-22 1989-12-19 Postupak za izradu transdermalnog terapijskog sistema sa fizostigminom kao aktivnim sastojkom

Country Status (29)

Country Link
US (1) US5391375A (sh)
EP (1) EP0377147B1 (sh)
JP (1) JPH0784380B2 (sh)
KR (1) KR950015057B1 (sh)
CN (1) CN1044226A (sh)
AT (1) ATE105489T1 (sh)
AU (1) AU613814B2 (sh)
CA (1) CA2006398C (sh)
CS (1) CS277067B6 (sh)
DD (1) DD290582A5 (sh)
DE (2) DE3843238C1 (sh)
DK (1) DK651189A (sh)
ES (1) ES2057080T3 (sh)
FI (1) FI95774C (sh)
GE (1) GEP19980993B (sh)
HU (1) HU206041B (sh)
IE (1) IE64834B1 (sh)
IL (1) IL92679A0 (sh)
LT (1) LT3705B (sh)
LV (1) LV10383B (sh)
MY (1) MY105073A (sh)
NO (1) NO180107C (sh)
NZ (1) NZ231908A (sh)
PH (1) PH25852A (sh)
PL (1) PL160971B1 (sh)
PT (1) PT92651B (sh)
RU (1) RU2052997C1 (sh)
YU (1) YU47076B (sh)
ZA (1) ZA899882B (sh)

Families Citing this family (31)

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DE3843239C1 (sh) * 1988-12-22 1990-02-22 Lohmann Therapie Syst Lts
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
GB9118028D0 (en) * 1991-08-21 1991-10-09 Secr Defence Brit Improved transdrmal formulations
WO1994001795A1 (en) * 1992-07-13 1994-01-20 Seiko Epson Corporation Surface illumination device and liquid crystal display
DE4238223C1 (de) * 1992-11-12 1994-05-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Verabreichung von Physostigmin an die Haut und Verfahren zu dessen Herstellung
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
DE4332094C2 (de) * 1993-09-22 1995-09-07 Lohmann Therapie Syst Lts Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung
DE4342174C1 (de) * 1993-12-10 1995-05-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System sowie ein Verfahren zur Herstellung eines transdermalen therapeutischen Systems zur kombinierten transdermalen Anwendung von Physostigmin und Scopolamin für die Prophylaxe und zur Vorbehandlung einer Vergiftung durch hochtoxische phosphororganische Nervengifte, insbesondere Soman und seine Verwendung
DE4429791C2 (de) * 1994-08-23 1997-04-24 Lohmann Therapie Syst Lts Medizinischer Haftkleber auf Basis von Polyacrylaten und dessen Verwendung
US20070179197A1 (en) * 2000-05-01 2007-08-02 Accera, Inc. Compositions and methods for improving or preserving brain function
US6440465B1 (en) * 2000-05-01 2002-08-27 Bioderm, Inc. Topical composition for the treatment of psoriasis and related skin disorders
US6835750B1 (en) 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
US20020006959A1 (en) * 2000-05-01 2002-01-17 Henderson Samuel T. Use of medium chain triglycerides for the treatment and prevention of Alzheimer's Disease and other diseases resulting from reduced Neuronal Metabolism
WO2004077938A2 (en) * 2003-03-06 2004-09-16 Accera Inc. Novel chemical entities and methods for their use in treatment of metabolic disorders
US20060252775A1 (en) * 2005-05-03 2006-11-09 Henderson Samuel T Methods for reducing levels of disease associated proteins
WO2007001883A2 (en) * 2005-06-20 2007-01-04 Accera, Inc. Method to reduce oxidative damage and improve mitochondrial efficiency
HUE035852T2 (en) 2006-04-03 2018-05-28 Accera Inc Use of ketogen compounds to treat memory decline
KR101335021B1 (ko) 2007-07-31 2013-12-12 액세라인크 게놈 테스트의 용도 및 인지 기능 저하 치료용 케톤성 화합물
KR101734152B1 (ko) * 2008-07-03 2017-05-11 액세라인크 신경계 장애의 치료를 위한 아세토아세테이트의 모노글리세리드 및 유도체
US8105809B2 (en) * 2008-07-03 2012-01-31 Accera, Inc. Enzymatic synthesis of acetoacetate esters and derivatives
ITPI20090066A1 (it) * 2009-05-26 2010-11-27 Consiglio Nazionale Ricerche Metodo per produrre un dispositivo applicabile a tessuti biologici, in particolare un patch per trattare tessuti danneggiati, e dispositivo ottenuto con tale metodo
DE102009056745A1 (de) * 2009-12-04 2011-06-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung von Peptiden
US8828181B2 (en) 2010-04-30 2014-09-09 E I Du Pont De Nemours And Company Temperature switchable adhesives comprising a crystallizable oil
US8409703B2 (en) 2010-07-23 2013-04-02 E I Du Pont De Nemours And Company Temperature switchable adhesive assemblies with temperature non-switchable tack
DE102019201430A1 (de) 2019-02-05 2020-08-06 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit Transportmedium
DE102019201431A1 (de) 2019-02-05 2020-08-06 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit Feststoffreservoir
EP3989950A4 (en) * 2019-06-28 2023-07-19 PassPort Technologies, Inc. TRANSDERMAL DELIVERY PATCH, DELIVERY SYSTEM AND DELIVERY PROCEDURE

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DE3843239C1 (sh) * 1988-12-22 1990-02-22 Lohmann Therapie Syst Lts

Also Published As

Publication number Publication date
FI95774B (fi) 1995-12-15
CS277067B6 (en) 1992-11-18
CA2006398A1 (en) 1990-06-22
NO180107B (no) 1996-11-11
PT92651B (pt) 1995-09-12
GEP19980993B (en) 1998-03-26
DK651189D0 (da) 1989-12-20
AU613814B2 (en) 1991-08-08
NO895172L (no) 1990-06-25
KR950015057B1 (ko) 1995-12-21
IE894078L (en) 1990-06-22
NZ231908A (en) 1991-10-25
AU4684489A (en) 1990-06-28
FI896098A0 (fi) 1989-12-19
DE58907649D1 (de) 1994-06-16
US5391375A (en) 1995-02-21
LV10383B (en) 1995-10-20
KR900009064A (ko) 1990-07-02
DE3843238C1 (sh) 1990-02-22
CN1044226A (zh) 1990-08-01
LT3705B (en) 1996-02-26
CA2006398C (en) 1997-04-15
HU896714D0 (en) 1990-02-28
IE64834B1 (en) 1995-09-06
DK651189A (da) 1990-06-23
PL160971B1 (en) 1993-05-31
HUT54043A (en) 1991-01-28
NO895172D0 (no) 1989-12-21
IL92679A0 (en) 1990-09-17
FI95774C (fi) 1996-03-25
ZA899882B (en) 1990-09-26
EP0377147A2 (de) 1990-07-11
HU206041B (en) 1992-08-28
ES2057080T3 (es) 1994-10-16
JPH0784380B2 (ja) 1995-09-13
ATE105489T1 (de) 1994-05-15
MY105073A (en) 1994-07-30
DD290582A5 (de) 1991-06-06
LV10383A (lv) 1995-02-20
LTIP1589A (en) 1995-06-26
CS719289A3 (en) 1992-06-17
YU240689A (en) 1991-04-30
EP0377147B1 (de) 1994-05-11
RU2052997C1 (ru) 1996-01-27
EP0377147A3 (en) 1990-12-27
JPH0315476A (ja) 1991-01-23
PH25852A (en) 1991-12-02
PT92651A (pt) 1990-06-29
NO180107C (no) 1997-02-26

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