YU46814B - Fuzioni polipeptid koji sadrži dvojne jedinice ponavljanja cirkumsporozoitnog (cs) proteina plasmodium falciparum - Google Patents

Fuzioni polipeptid koji sadrži dvojne jedinice ponavljanja cirkumsporozoitnog (cs) proteina plasmodium falciparum

Info

Publication number
YU46814B
YU46814B YU18286A YU18286A YU46814B YU 46814 B YU46814 B YU 46814B YU 18286 A YU18286 A YU 18286A YU 18286 A YU18286 A YU 18286A YU 46814 B YU46814 B YU 46814B
Authority
YU
Yugoslavia
Prior art keywords
protein
sporozoit
circum
fusion polypeptide
polypeptide containing
Prior art date
Application number
YU18286A
Other languages
English (en)
Other versions
YU18286A (en
Inventor
R. Ballouw
M.S. Gross
W.T. Hockmeyer
J.F. Young
Original Assignee
Smithkline Beckman Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp. filed Critical Smithkline Beckman Corp.
Publication of YU18286A publication Critical patent/YU18286A/xx
Publication of YU46814B publication Critical patent/YU46814B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

FUZIONI POLIPEPTID KOJI SADRŽI DVOJNE JEDINICE PONAVLJANJA CIRKUMSPOROZOITNOG (CS) PROTEINA PLASMODIUM FALCIPARUM - naznačen time, što je ponavljajuća sekvenca proteina različitog od CS proteina odabrana iz grupe koja obuhvata Gly-Leu-Arg nestrukturne proteine 1 (NS1) virusa influence; 81 N-terminalnih amino kiselina iz proizvoda gena otpornosti na tetraciklin (tet86); i 32 N-terminalne amino kiseline iz proizvoda gena otpornosti na tetraciklin (tet32); i što su dvojne jedinice ponavljanja predstavljene formulom: / (Asn-Ala-Asn-Pro)15 (Asn-Val-Asp-Pro)1/n gde je n 1. Prijava sadrži još 8 zavisnih i 1 nezavisan zahtev.
YU18286A 1985-02-07 1986-02-07 Fuzioni polipeptid koji sadrži dvojne jedinice ponavljanja cirkumsporozoitnog (cs) proteina plasmodium falciparum YU46814B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69911685A 1985-02-07 1985-02-07

Publications (2)

Publication Number Publication Date
YU18286A YU18286A (en) 1989-12-31
YU46814B true YU46814B (sh) 1994-06-10

Family

ID=24808007

Family Applications (1)

Application Number Title Priority Date Filing Date
YU18286A YU46814B (sh) 1985-02-07 1986-02-07 Fuzioni polipeptid koji sadrži dvojne jedinice ponavljanja cirkumsporozoitnog (cs) proteina plasmodium falciparum

Country Status (18)

Country Link
EP (1) EP0192626B1 (sh)
JP (1) JPH0689032B2 (sh)
CN (1) CN86100428A (sh)
AP (1) AP18A (sh)
AT (1) ATE78869T1 (sh)
AU (2) AU5293486A (sh)
DE (1) DE3686178T2 (sh)
DK (1) DK167817B1 (sh)
ES (1) ES8801126A1 (sh)
GR (1) GR860352B (sh)
HU (1) HU201682B (sh)
IE (1) IE58829B1 (sh)
IL (1) IL77787A0 (sh)
NZ (1) NZ215023A (sh)
OA (1) OA08200A (sh)
PT (1) PT81974B (sh)
YU (1) YU46814B (sh)
ZA (1) ZA86874B (sh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707357A (en) * 1984-06-26 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
ZA855232B (en) * 1984-07-23 1986-02-26 Univ New York Protective peptide antigen corresponding to plasmodium falciparum circumsporozoite protein
IT1187710B (it) * 1985-07-25 1987-12-23 Eniricerche Spa Composizione peptidica utile per la preparazione di vaccini per la malaria e di kit diagnostici per la determinazione di affezioni malariche
EP0252588A3 (en) * 1986-05-12 1989-07-12 Smithkline Beecham Corporation Process for the isolation and purification of p. falciparum cs protein expressed in recombinant e. coli, and its use as a vaccine
EP0254862A1 (en) * 1986-06-26 1988-02-03 BEHRINGWERKE Aktiengesellschaft Vaccines against protozoan parasites
WO1988002757A1 (en) * 1986-10-17 1988-04-21 Saramane Pty. Ltd.; Hybrid proteins or polypeptides
HUT51332A (en) * 1987-01-30 1990-04-28 Smithkline Biolog Process for expressing p.falciparum cirkumsporozoita protein by yeast
US6093406A (en) * 1988-06-02 2000-07-25 The United States Of America As Represented By The Secretary Of The Army Vaccine for induction of immunity to malaria
NZ233255A (en) * 1989-04-11 1993-02-25 Chiron Corp Plasmodium cs protein analogues lacking one or more of the repeat epitopes, and containing at least one nonrepeat flanking epitope
JP2513316B2 (ja) * 1989-06-09 1996-07-03 富士ゼロックス株式会社 画像読取装置
CA2037151A1 (en) * 1990-03-23 1991-09-24 F. Hoffmann-La Roche Ag Plasmodium sporozoite antigen
AU6158700A (en) * 1999-07-13 2001-01-30 Corixa Corporation Vaccine
JP2002371098A (ja) * 2001-06-11 2002-12-26 Japan Atom Energy Res Inst マラリア感染診断材及びマラリア原虫の増殖を抑える免疫用抗原
US8728492B2 (en) * 2008-01-18 2014-05-20 Aeras Global Tb Vaccine Foundation Malaria vaccine compositions and constituents which elicit cell mediated immunity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466917A (en) * 1981-02-12 1984-08-21 New York University Malaria vaccine
GB2145092B (en) * 1983-01-28 1988-04-07 Univ New York Protective peptide antigen
DE3280028D1 (en) * 1981-05-21 1989-12-28 Wellcome Found Protozoal antigen
AU569722B2 (en) * 1983-01-28 1988-02-18 Saramane Pty Ltd Expression of plasmodium falciparum polypeptides from cloned cdna
AU584881B2 (en) * 1984-02-21 1989-06-08 British Technology Group Limited Improvements in or relating to the production of malaria vaccines
US4707357A (en) * 1984-06-26 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
ZA855232B (en) * 1984-07-23 1986-02-26 Univ New York Protective peptide antigen corresponding to plasmodium falciparum circumsporozoite protein
CN86100979A (zh) * 1985-02-07 1986-12-17 史密丝克莱恩贝克曼公司 疟疾疫苗的制备方法
JP2659198B2 (ja) * 1986-11-12 1997-09-30 日本電気株式会社 画像２値化装置

Also Published As

Publication number Publication date
IE860336L (en) 1986-08-07
DE3686178D1 (de) 1992-09-03
AP8600021A0 (en) 1986-02-01
ES551657A0 (es) 1987-12-16
ATE78869T1 (de) 1992-08-15
JPS6237A (ja) 1987-01-06
AU8260991A (en) 1991-11-28
OA08200A (en) 1987-10-30
EP0192626A1 (en) 1986-08-27
NZ215023A (en) 1989-07-27
CN86100428A (zh) 1987-01-21
HU201682B (en) 1990-12-28
IL77787A0 (en) 1986-07-31
DE3686178T2 (de) 1993-03-11
IE58829B1 (en) 1993-11-17
JPH0689032B2 (ja) 1994-11-09
DK167817B1 (da) 1993-12-20
EP0192626B1 (en) 1992-07-29
ZA86874B (en) 1986-12-30
GR860352B (en) 1986-06-05
AU639588B2 (en) 1993-07-29
DK62386A (da) 1986-08-08
AU5293486A (en) 1986-08-14
YU18286A (en) 1989-12-31
AP18A (en) 1988-04-02
PT81974A (en) 1986-03-01
HUT41844A (en) 1987-05-28
ES8801126A1 (es) 1987-12-16
DK62386D0 (da) 1986-02-07
PT81974B (pt) 1988-07-01

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