KR890005269A - 재조합 아비폭스비루스 - Google Patents
재조합 아비폭스비루스 Download PDFInfo
- Publication number
- KR890005269A KR890005269A KR1019880012033A KR880012033A KR890005269A KR 890005269 A KR890005269 A KR 890005269A KR 1019880012033 A KR1019880012033 A KR 1019880012033A KR 880012033 A KR880012033 A KR 880012033A KR 890005269 A KR890005269 A KR 890005269A
- Authority
- KR
- South Korea
- Prior art keywords
- recombinant
- abipoxvirus
- cdna
- base sequence
- poultry
- Prior art date
Links
- 239000002299 complementary DNA Substances 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 3
- 244000144977 poultry Species 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 101710154606 Hemagglutinin Proteins 0.000 claims 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
- 101710176177 Protein A56 Proteins 0.000 claims 1
- 230000000840 anti-viral effect Effects 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- 230000036039 immunity Effects 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도, 제2도 및 제3도는 재조합 아비폭스비루스의 재작과정을 나타낸다.
Claims (6)
- 아미폭스비루스의 증식에 비-필수적인 게놈 영역에 뉴우켓슬병 비루스-유래 혈구 응집소 뉴우라미니다제를 코딩하는 cDNA의 전부 또는 일부를 삽입시킨 재조합 아비폭스비루스.
- 제1항에 있어서,cDNA가 프로모터의 통제하에 있는 재조합 아비폭스비루스.
- 제1항 또는 제2항에 있어서, cDNA가 제4도에 나타낸 아미노산 서열 또는 그 아미노산 서열과 실질적으로 동일한 기능을 갖는 폴리펩티드를 코딩하는 재조합 아비폭스비루스.
- 제1항 또는 제2항에 있어서, cDNA가 제4도에 나타낸 염기 서열 또는 그 염기 서열과 실질적으로 동일한 기능을 갖는 염기 서열을 갖는 재조합 아비폭스비루스.
- 제1항 내지 제4항중 어느 한 항의 재조합 아비폭스비루스를 함유하는 가금용 백신.
- 제1항 또는 제2항의 재조합 아비폭스비루스를 함유하는 가금에게 포울폭스 비루스 및 뉴유켓슬병 비루스에 대한 항-비루스 면역성을 부여할수 있는 가금용 백신.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP231653/87 | 1987-09-16 | ||
JP23165387 | 1987-09-16 | ||
JP62-231653 | 1987-09-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR890005269A true KR890005269A (ko) | 1989-05-13 |
KR970000530B1 KR970000530B1 (ko) | 1997-01-13 |
Family
ID=16926866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880012033A KR970000530B1 (ko) | 1987-09-16 | 1988-09-16 | 재조합 아비폭스비루스 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0308220B1 (ko) |
KR (1) | KR970000530B1 (ko) |
AU (1) | AU611711B2 (ko) |
CA (1) | CA1340203C (ko) |
DE (1) | DE3850019T2 (ko) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0414689B1 (en) * | 1988-02-12 | 1994-12-07 | Commonwealth Scientific And Industrial Research Organisation | Pox virus vectors |
DE3813093A1 (de) * | 1988-04-19 | 1989-11-09 | Immuno Ag | Rekombinantes plasmid, verfahren zum herstellen eines rekombinanten avipoxvirus, rekombinantes avipoxvirus und dessen verwendung |
US5631154A (en) * | 1988-06-10 | 1997-05-20 | Therion Biologics, Incorporated | Self assembled, defective, non-self-propagating lentivirus particles |
DE68912441T2 (de) * | 1988-06-24 | 1994-05-11 | British Tech Group | Nichtessentielle Geflügelpockenvirus-Regionen. |
US5093258A (en) * | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
KR940001265B1 (ko) * | 1988-12-29 | 1994-02-18 | 닛뽕 제온 가부시끼가이샤 | 프로모터, 그를 함유하는 플라스미드 및 재조합 아비폭스비루스 |
JP2781605B2 (ja) * | 1989-06-22 | 1998-07-30 | 日本ゼオン株式会社 | 組み換えアビポックスウイルス |
WO1992000372A1 (en) * | 1990-07-02 | 1992-01-09 | Smithkline Beecham Corporation | Recombinant pigeon pox virus vaccine |
ATE253123T1 (de) * | 1991-08-26 | 2003-11-15 | Baxter Healthcare Sa | Ein intaktes fpv-tk-gen enthaltender rekombinanter virus der vogelpocken |
US5925358A (en) * | 1993-02-26 | 1999-07-20 | Syntro Corporation | Recombinant fowlpox viruses and uses thereof |
US6136318A (en) * | 1993-02-26 | 2000-10-24 | Cochran; Mark D. | Recombinant fowlpox viruses and uses thereof |
EP0696204A4 (en) * | 1993-02-26 | 1999-03-31 | Syntro Corp | Recombined chickenpox virus and its use |
DE69433976T2 (de) * | 1993-03-31 | 2005-09-01 | Zeon Corp. | Neuartige Polypeptide, ihre DNA, rekombinanter Vektor, der letztere enthält, mit diesem hergestelltes rekombinantes Virus und seine Verwendung |
WO1998004727A1 (en) | 1996-07-25 | 1998-02-05 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
CA2351622A1 (en) | 1998-11-18 | 2000-05-25 | Oxford Biomedica (Uk) Limited | Polypeptide |
CA2515890C (en) | 2003-02-20 | 2013-09-17 | Therion Biologics Corporation | Novel insertion sites in pox vectors |
EP1888634A2 (en) | 2005-05-13 | 2008-02-20 | Oxford Biomedica (UK) Limited | Mhc class i and ii peptide antigens derived from tumour antigen 5t4 |
EP2397852B1 (en) | 2006-03-14 | 2013-12-04 | Oregon Health and Science University | Methods for detecting a mycobacterium tuberculosis infection |
EP2125868B1 (en) | 2007-02-28 | 2015-06-10 | The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
US8691502B2 (en) | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
WO2010099472A2 (en) | 2009-02-27 | 2010-09-02 | The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services | Spanx-b polypeptides and their use |
EP3360566B1 (en) | 2009-11-20 | 2019-12-25 | Oregon Health&Science University | Methods for detecting a mycobacterium tuberculosis infection |
WO2012151272A2 (en) | 2011-05-02 | 2012-11-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
EP2788021B1 (en) | 2011-12-09 | 2017-01-18 | Bavarian Nordic A/S | Poxvirus vector for the expression of bacterial antigens linked to tetanus toxin fragment c |
WO2014043535A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions for the treatment of cancer |
HUE051897T2 (hu) | 2015-03-18 | 2021-03-29 | Janssen Vaccines & Prevention Bv | Vizsgálatok rekombináns expressziós rendszerekre |
WO2023077147A2 (en) | 2021-11-01 | 2023-05-04 | Pellis Therapeutics, Inc. | T-cell vaccines for patients with reduced humoral immunity |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0190254A4 (en) * | 1984-07-05 | 1987-03-09 | Genex Corp | GENE CLONE AND PROCESS FOR THE PREPARATION AND USE THEREOF. |
DE3650289T2 (de) * | 1985-03-29 | 1995-08-10 | British Tech Group | Spike-protein des virus der infektiösen bronchitis. |
AU602875B2 (en) * | 1985-12-18 | 1990-11-01 | British Technology Group Limited | Newcastle disease virus gene clones |
ZA874677B (en) * | 1986-06-30 | 1988-11-30 | Smith Kline Rit | Dna sequence,recombinant dna molecules and process for producing the newcastle disease virus fusion protein or equivalent polypeptides,obtained products and preparations containing same |
WO1988002022A1 (en) * | 1986-09-22 | 1988-03-24 | Commonwealth Scientific And Industrial Research Or | Recombinant poxviruses |
EP0284416B1 (en) * | 1987-03-27 | 1995-02-22 | Nippon Zeon Co., Ltd. | Recombinant avipoxyvirus |
CA1341245C (en) * | 1988-01-12 | 2001-06-05 | F. Hoffmann-La Roche Ag | Recombinant vaccinia virus mva |
-
1988
- 1988-09-14 CA CA000577368A patent/CA1340203C/en not_active Expired - Fee Related
- 1988-09-15 EP EP88308532A patent/EP0308220B1/en not_active Expired - Lifetime
- 1988-09-15 AU AU22228/88A patent/AU611711B2/en not_active Ceased
- 1988-09-15 DE DE3850019T patent/DE3850019T2/de not_active Expired - Lifetime
- 1988-09-16 KR KR1019880012033A patent/KR970000530B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR970000530B1 (ko) | 1997-01-13 |
DE3850019T2 (de) | 1994-12-01 |
CA1340203C (en) | 1998-12-15 |
AU2222888A (en) | 1989-03-16 |
AU611711B2 (en) | 1991-06-20 |
EP0308220B1 (en) | 1994-06-08 |
DE3850019D1 (de) | 1994-07-14 |
EP0308220A1 (en) | 1989-03-22 |
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