FR2621487B1 - Virus avipox recombinant - Google Patents

Virus avipox recombinant

Info

Publication number
FR2621487B1
FR2621487B1 FR888811334A FR8811334A FR2621487B1 FR 2621487 B1 FR2621487 B1 FR 2621487B1 FR 888811334 A FR888811334 A FR 888811334A FR 8811334 A FR8811334 A FR 8811334A FR 2621487 B1 FR2621487 B1 FR 2621487B1
Authority
FR
France
Prior art keywords
avipox virus
recombinant avipox
recombinant
virus
avipox
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR888811334A
Other languages
English (en)
Other versions
FR2621487A1 (fr
Inventor
Enzo Paoletti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Health Research Inc
Original Assignee
Health Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27492413&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2621487(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Health Research Inc filed Critical Health Research Inc
Publication of FR2621487A1 publication Critical patent/FR2621487A1/fr
Application granted granted Critical
Publication of FR2621487B1 publication Critical patent/FR2621487B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24041Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20111Lyssavirus, e.g. rabies virus
    • C12N2760/20122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR888811334A 1987-08-28 1988-08-29 Virus avipox recombinant Expired - Lifetime FR2621487B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9071187A 1987-08-28 1987-08-28
US11033587A 1987-10-20 1987-10-20
US18605488A 1988-04-25 1988-04-25
US23439088A 1988-08-23 1988-08-23

Publications (2)

Publication Number Publication Date
FR2621487A1 FR2621487A1 (fr) 1989-04-14
FR2621487B1 true FR2621487B1 (fr) 1991-10-18

Family

ID=27492413

Family Applications (1)

Application Number Title Priority Date Filing Date
FR888811334A Expired - Lifetime FR2621487B1 (fr) 1987-08-28 1988-08-29 Virus avipox recombinant

Country Status (17)

Country Link
JP (3) JP3348156B2 (fr)
KR (1) KR970011149B1 (fr)
AR (1) AR241939A1 (fr)
AT (1) AT408549B (fr)
AU (2) AU2427588A (fr)
BE (1) BE1002134A5 (fr)
CH (2) CH679933A5 (fr)
DE (4) DE10399032I1 (fr)
DK (1) DK175904B1 (fr)
FR (1) FR2621487B1 (fr)
GB (1) GB2217718B (fr)
IL (1) IL87581A0 (fr)
IT (1) IT1229484B (fr)
LU (2) LU90951I2 (fr)
NL (4) NL195051C (fr)
NZ (1) NZ225970A (fr)
WO (1) WO1989003429A1 (fr)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338683A (en) * 1981-12-24 1994-08-16 Health Research Incorporated Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins
US5505941A (en) * 1981-12-24 1996-04-09 Health Research, Inc. Recombinant avipox virus and method to induce an immune response
US7045313B1 (en) 1982-11-30 2006-05-16 The United States Of America As Represented By The Department Of Health And Human Services Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA
DE10399032I1 (de) * 1987-08-28 2004-01-29 Health Research Inc Rekombinante Viren.
US5286639A (en) * 1987-09-16 1994-02-15 Nippon Zeon Co., Ltd. Recombinant avipoxvirus
DE3813093A1 (de) * 1988-04-19 1989-11-09 Immuno Ag Rekombinantes plasmid, verfahren zum herstellen eines rekombinanten avipoxvirus, rekombinantes avipoxvirus und dessen verwendung
US5631154A (en) * 1988-06-10 1997-05-20 Therion Biologics, Incorporated Self assembled, defective, non-self-propagating lentivirus particles
GB2220941B (en) * 1988-06-24 1991-09-11 Nat Res Dev Fowlpox virus non-essential regions
US5093258A (en) * 1988-08-26 1992-03-03 Therion Biologics Corporation Recombinant fowlpox virus and recombination vector
CA2001001A1 (fr) * 1988-10-21 1990-04-21 Matthew M. Binns Promoteur du virus de l'acne molluscum
US6248333B1 (en) 1990-04-04 2001-06-19 Health Research Inc. Isolated nucleic acid sequence of equine herpesvirus type 1 glycoprotein D (EHV-1 gD)
US5204243A (en) * 1990-02-14 1993-04-20 Health Research Incorporated Recombinant poxvirus internal cores
MY109299A (en) * 1990-08-15 1996-12-31 Virogenetics Corp Recombinant pox virus encoding flaviviral structural proteins
US5514375A (en) * 1990-08-15 1996-05-07 Virogenetics Corporation Flavivirus recombinant poxvirus vaccine
FR2668064B1 (fr) * 1990-10-23 1994-12-16 Transgene Sa Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne.
US6309647B1 (en) 1999-07-15 2001-10-30 Aventis Pasteur Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants
US5503834A (en) * 1990-11-20 1996-04-02 Virogenetics Corporation Measles virus recombinant poxvirus vaccine
US5756102A (en) * 1990-11-20 1998-05-26 Virogenetics Corporation Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants
IE71643B1 (en) * 1990-11-20 1997-02-26 Virogenetics Corp A recombinant poxviral vaccine for canine distemper
US5759841A (en) * 1990-11-20 1998-06-02 Virogenetics Corporation Immunological composition of measles virus utilizing recombinant poxvirus
US5338679A (en) * 1991-01-08 1994-08-16 Her Majesty The Queen In Right Of Canada, As Represented By National Research Council Canada And Forestry Canada Vertebrate poxvoris expression vector under the control of entomopoxvirus spheroidin gene promoter
US5766597A (en) * 1991-03-07 1998-06-16 Virogenetics Corporation Malaria recombinant poxviruses
AU672581B2 (en) * 1991-03-07 1996-10-10 Virogenetics Corporation Immunodeficiency virus recombinant poxvirus vaccine
US5863542A (en) * 1991-03-07 1999-01-26 Virogenetics Corporation Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts
US5766598A (en) * 1991-03-07 1998-06-16 Virogenetics Corporation Recombinant attenuated ALVAC canarypoxvirus expression vectors containing heterologous DNA segments encoding lentiviral gene products
US5756101A (en) * 1991-07-01 1998-05-26 Pasteur Merieux Serums Et Vaccins Malaria recombinant poxvirus
KR100242671B1 (ko) * 1991-03-07 2000-03-02 고돈 에릭 유전학적으로 처리한 백신 균주
WO1992016616A1 (fr) * 1991-03-20 1992-10-01 Virogenetics Corporation Vaccin contre le poxvirus de recombinaison de la malaria
EP0597016A4 (en) * 1991-07-26 1996-04-24 Virogenetics Corp Infectious bursal disease virus recombinant poxvirus vaccine.
EP0538496B1 (fr) * 1991-08-26 2003-10-29 Baxter Healthcare S.A. Virus de la variole aviaire recombinant comportant un gène FPV-tk intact
US5443831A (en) * 1991-10-29 1995-08-22 University Of Delaware Gene encoding glycoprotein B of Infectious Laryngotracheitis Virus
US6497882B1 (en) 1992-01-13 2002-12-24 Syntro Corporation Recombinant swinepox virus
US6033904A (en) * 1992-01-13 2000-03-07 Syntro Corporation Recombinant swinepox virus
US6328975B1 (en) 1992-01-13 2001-12-11 Syntro Corporation Recombinant swinepox virus
PT623172E (pt) * 1992-01-13 2005-02-28 Virogenetics Corp Vacina de virus vaccinia recombinante do virus da doenca de marek
US6127163A (en) * 1992-01-13 2000-10-03 Syntro Corporation Recombinant swinepox virus
US5869312A (en) * 1992-01-13 1999-02-09 Syntro Corporation Recombinant swinepox virus
US6251403B1 (en) 1992-01-13 2001-06-26 Syntro Corporation Recombinant swinepox virus
CA2142325A1 (fr) * 1992-09-21 1994-03-31 William T. L. Lee Vecteur retroviral recombinant agissant contre felv et (ou) fiv
US5925358A (en) * 1993-02-26 1999-07-20 Syntro Corporation Recombinant fowlpox viruses and uses thereof
US6136318A (en) * 1993-02-26 2000-10-24 Cochran; Mark D. Recombinant fowlpox viruses and uses thereof
AU727278B2 (en) * 1993-02-26 2000-12-07 Syntro Corporation Recombinant fowlpox viruses and uses thereof II
EP0696204A4 (fr) * 1993-02-26 1999-03-31 Syntro Corp Virus recombinants de la diphterie des volailles et utilisations
US5496731A (en) * 1993-03-25 1996-03-05 Xu; Hong-Ji Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy
US5843742A (en) * 1994-12-16 1998-12-01 Avigen Incorporated Adeno-associated derived vector systems for gene delivery and integration into target cells
EP0753581A1 (fr) 1995-07-10 1997-01-15 Immuno Ag Virus recombinantes eucaryotes cytoplasmiques améliorés, un procédé pour leur préparation et leur utilisation comme vaccins
US5858373A (en) * 1995-12-01 1999-01-12 Virogenetics Corporation Recombinant poxvirus-feline infectious peritionitis virus, compositions thereof and methods for making and using them
EP2112225A1 (fr) 1996-07-25 2009-10-28 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Poxvirus recombinant pour l'immunisation contre les antigènes associés aux tumeurs
US6106825A (en) * 1997-05-07 2000-08-22 University Of Florida Entomopoxvirus-vertebrate gene delivery vector and method
WO1999007869A1 (fr) * 1997-08-05 1999-02-18 University Of Florida Vaccin vivant recombinant comprenant un virus ne se repliquant pas ou se repliquant sans efficacite
US6248582B1 (en) * 1997-10-08 2001-06-19 Imran Khan Gene deleted recombinant FeLV proviral DNA for production of vaccines against FeLV
JPH11165762A (ja) 1997-12-01 1999-06-22 Lintec Corp チップ体搬送用カバーテープおよび封止構造体
US20020147143A1 (en) 1998-03-18 2002-10-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
US6221349B1 (en) 1998-10-20 2001-04-24 Avigen, Inc. Adeno-associated vectors for expression of factor VIII by target cells
US6200560B1 (en) 1998-10-20 2001-03-13 Avigen, Inc. Adeno-associated virus vectors for expression of factor VIII by target cells
US6602705B1 (en) 1998-12-31 2003-08-05 Chiron Corporation Expression of HIV polypeptides and production of virus-like particles
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
US6545127B1 (en) 1999-06-28 2003-04-08 Oklahoma Medical Research Foundation Catalytically active recombinant memapsin and methods of use thereof
ES2389445T3 (es) 2000-02-23 2012-10-26 Glaxosmithkline Biologicals Sa Compuestos novedosos
AU2001273149A1 (en) 2000-06-28 2002-01-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
EP2198882A3 (fr) 2001-01-12 2010-10-13 Novartis Vaccines and Diagnostics, Inc. Immunisation des muqueuses par acide nucléique
EP1370668B1 (fr) * 2001-03-08 2006-02-22 Akzo Nobel N.V. Vaccins vectoriels a base de leporipox
JP4499311B2 (ja) * 2001-04-27 2010-07-07 シャープ株式会社 放送受信端末
CA2446788A1 (fr) 2001-05-09 2002-11-14 Corixa Corporation Compositions et procedes pour la therapie et le diagnostic du cancer de la prostate
US7211659B2 (en) 2001-07-05 2007-05-01 Chiron Corporation Polynucleotides encoding antigenic HIV type C polypeptides, polypeptides and uses thereof
EP2292772A1 (fr) 2001-07-05 2011-03-09 Novartis Vaccines and Diagnostics, Inc. Vaccination VIH avec un ADN codant un polypeptide VIH et un polypeptide VIH
EP2224012B1 (fr) 2001-12-17 2013-01-30 Corixa Corporation Compositions et procédés pour la thérapie et le diagnostic de maladies intestines inflammatoires
RU2389732C2 (ru) 2003-01-06 2010-05-20 Корикса Корпорейшн Некоторые аминоалкилглюкозаминидфосфатные производные и их применение
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
WO2005007808A2 (fr) 2003-05-15 2005-01-27 Chiron Corporation Polynucleotides pour vih et polypeptides derives de botswana mj4
US7261882B2 (en) 2003-06-23 2007-08-28 Reagents Of The University Of Colorado Methods for treating neuropathic pain by administering IL-10 polypeptides
KR101505496B1 (ko) 2004-09-22 2015-03-25 글락소스미스클라인 바이오로지칼즈 에스.에이. 스태필로코쿠스에 대한 예방접종에 사용하기 위한 면역원성 조성물
ES2514316T3 (es) 2005-11-22 2014-10-28 Novartis Vaccines And Diagnostics, Inc. Partículas similares a virus (VLPs) de Norovirus y Sapovirus
AU2007239095B2 (en) 2006-01-09 2012-05-03 The Regents Of The University Of California Immunostimulatory combinations for vaccine adjuvants
BRPI0708865A8 (pt) 2006-03-14 2019-01-22 Univ Oregon Health & Science métodos para produzir uma resposta imune à tuberculose
EP2125868B1 (fr) 2007-02-28 2015-06-10 The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services Polypeptides brachyury et procédés d'utilisation
US20120040367A1 (en) 2007-10-15 2012-02-16 The University Of Queensland Construct system and uses therefor
US8691502B2 (en) 2008-10-31 2014-04-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
EP2384120B1 (fr) 2009-01-05 2019-12-11 Epitogenesis Inc. Compositions adjuvantes et méthodes d'utilisation
WO2010099472A2 (fr) 2009-02-27 2010-09-02 The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services Polypeptides spanx-b et leur utilisation
US8961989B2 (en) 2009-11-20 2015-02-24 Oregon Health & Science University Methods for producing an immune response to tuberculosis
WO2011106705A2 (fr) 2010-02-26 2011-09-01 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Protocoles de vaccination adn/protéine
US9795658B2 (en) 2010-04-20 2017-10-24 Admedus Vaccines Pty Ltd Expression system for modulating an immune response
US9428565B2 (en) 2011-01-31 2016-08-30 The General Hospital Corporation Treatment and bioluminescent visualization using multimodal TRAIL molecules
WO2012151272A2 (fr) 2011-05-02 2012-11-08 Tremrx, Inc. Vaccination avec des lymphocytes t à l'aide de vecteurs viraux par rupture épidermique mécanique
CN103608030A (zh) 2011-06-21 2014-02-26 昂科发克特公司 用于治疗和诊断癌症的组合物和方法
BR112013032410A2 (pt) 2011-06-24 2017-01-17 Epitogenesis Inc composições farmacêuticas compreendendo uma combinação de veículos, vitaminas, taninos e flavonoides de seleção como imunomoduladores específicos de antígeno
US20150004144A1 (en) 2011-12-02 2015-01-01 The General Hospital Corporation Differentiation into brown adipocytes
WO2014035474A1 (fr) 2012-08-30 2014-03-06 The General Hospital Corporation Compositions et méthodes de traitement du cancer
WO2014043535A1 (fr) 2012-09-14 2014-03-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions destinées à traiter le cancer
WO2014043518A1 (fr) 2012-09-14 2014-03-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Protéine brachyury, vecteurs non levure, non poxvirus, codant pour la protéine brachyury, et leur utilisation
MX2015014568A (es) 2013-04-17 2016-12-02 Genzyme Corp Composiciones y metodos para tratar y prevenir la degeneracion macular.
EP3848044A1 (fr) 2013-05-21 2021-07-14 President and Fellows of Harvard College Compositions se liant à l'hème manipulées et leurs utilisations
CA2930693A1 (fr) 2013-11-15 2015-05-21 The Board Of Trustees Of The Leland Stanford Junior Unversity Procedes de traitement d'une insuffisance cardiaque avec des agonistes de recepteur 2 d'hypocretine
MX2016010215A (es) 2014-02-06 2016-11-15 Genzyme Corp Composiciones y metodos de tratamiento y prevencion de degeneracion macular.
WO2016044707A1 (fr) 2014-09-18 2016-03-24 Cedars-Sinai Medical Center Compositions et procédés de traitement de la fibrose
US20180071380A1 (en) 2015-03-20 2018-03-15 The Regents Of The University Of Michigan Immunogenic compositions for use in vaccination against bordetella
WO2016168601A1 (fr) 2015-04-17 2016-10-20 Khalid Shah Agents, systèmes et méthodes de traitement du cancer
CN107708718B (zh) 2015-04-22 2022-01-11 西达-赛奈医疗中心 用于治疗2型糖尿病的肠内递送的苦味寡肽
EP3294755B1 (fr) 2015-05-13 2023-08-23 The United States of America as represented by the Secretary of the Department of Health and Human Services Methodes et compositions pour eliciter des reponses immune a base des constructs contenant des elements conservatives
WO2016196366A1 (fr) 2015-05-29 2016-12-08 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Extension de durée de vie réplicative dans des maladies de vieillissement prématuré à l'aide d'isoformes p53
WO2017004022A2 (fr) 2015-06-29 2017-01-05 The Board Of Trustees Of The Leland Stanford Junior University Constructions de fusion de degron et procédés de régulation de la production de protéine
EP3386593A4 (fr) 2015-12-09 2019-07-24 Admedus Vaccines Pty Ltd Composition immunomodulatrice pour le traitement
US11285191B2 (en) 2016-07-26 2022-03-29 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Immunostimulatory compositions and uses therefor
US10917454B1 (en) 2019-08-01 2021-02-09 Rohde & Schwarz Gmbh & Co. Kg System and method for ATC voice quality assurance
EP4419684A1 (fr) 2021-10-21 2024-08-28 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Leurres de facteur de transcription générés par rétro-éléments
WO2023077147A2 (fr) 2021-11-01 2023-05-04 Pellis Therapeutics, Inc. Vaccins à lymphocytes t pour patients présentant une immunité humorale réduite
EP4426832A1 (fr) 2021-11-03 2024-09-11 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Édition précise du génome à l'aide de rétrons
WO2023141602A2 (fr) 2022-01-21 2023-07-27 Renagade Therapeutics Management Inc. Rétrons modifiés et méthodes d'utilisation
WO2023183588A1 (fr) 2022-03-25 2023-09-28 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Procédés d'évaluation de l'activité rétronique modifiée et leurs utilisations
WO2023183627A1 (fr) 2022-03-25 2023-09-28 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Production d'adn transcrit inversé (adn-rt) au moyen d'une rétron transcriptase inverse à partir d'adn exogène
WO2023183589A1 (fr) 2022-03-25 2023-09-28 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Édition génomique à fidélité de rt-adn et à rétrons
WO2024020346A2 (fr) 2022-07-18 2024-01-25 Renagade Therapeutics Management Inc. Composants d'édition génique, systèmes et procédés d'utilisation
WO2024044673A1 (fr) 2022-08-24 2024-02-29 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Éditeurs de rétron à double coupe pour insertions et délétions génomiques
WO2024044723A1 (fr) 2022-08-25 2024-02-29 Renagade Therapeutics Management Inc. Rétrons modifiés et méthodes d'utilisation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK489481A (da) * 1980-11-10 1982-05-11 Searle & Co Plasmidvektor og frmgangsmaade til fremstilling deraf
US4603112A (en) * 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
WO1984002077A1 (fr) * 1982-11-30 1984-06-07 Us Health Procede de production de recombinants du virus de la variole pour l'expression de genes etrangers
FR2563434B1 (fr) * 1984-04-25 1986-07-25 Transgene Sa Vaccin contre la rage et procede pour sa preparation
EP0190254A4 (fr) * 1984-07-05 1987-03-09 Genex Corp Gene clone et son procede de preparation et d'utilisation.
DD235669A1 (de) * 1985-03-26 1986-05-14 Akad Wissenschaften Ddr Verfahren zur herstellung eines blv-kodierten huellproteins
US5032520A (en) * 1985-03-29 1991-07-16 National Research Development Corporation DNA sequences encoding infectious bronchitis virus spike protein
EP0213894A3 (fr) * 1985-08-23 1987-10-21 Advanced Genetics Research Institute Vaccins à particules virales imparfaites et méthodes d'utilisation
AU607399B2 (en) * 1985-09-09 1991-03-07 Cetus Corporation Infectious recombinant virus vaccine for feline leukemia
GR862412B (en) * 1985-09-25 1987-01-23 Oncogen Vaccines and immuinoassays for acquired immune deficiency syndrome
AU602875B2 (en) * 1985-12-18 1990-11-01 British Technology Group Limited Newcastle disease virus gene clones
AU8075787A (en) * 1986-09-22 1988-04-07 Australian National University, The Recombinant poxviruses
WO1988002022A1 (fr) * 1986-09-22 1988-03-24 Commonwealth Scientific And Industrial Research Or Virus de la variole recombinant
EP0261940A3 (fr) * 1986-09-23 1989-07-05 Applied Biotechnology, Inc. Vaccins pseudorabiques et vecteurs d'ADN pour recombiner avec les poxvirus
EP0284416B1 (fr) * 1987-03-27 1995-02-22 Nippon Zeon Co., Ltd. Avipoxvirus recombinant
DE10399032I1 (de) * 1987-08-28 2004-01-29 Health Research Inc Rekombinante Viren.
GB8724885D0 (en) * 1987-10-23 1987-11-25 Binns M M Fowlpox virus promotors
FR2632863B2 (fr) * 1987-10-29 1990-08-31 Transgene Sa Virus du fowlpox recombinant et vaccins derives de ces virus
GB2220941B (en) * 1988-06-24 1991-09-11 Nat Res Dev Fowlpox virus non-essential regions
JP3044062B2 (ja) * 1989-03-08 2000-05-22 ヘルス・リサーチ・インク 組換えポックスウイルス宿主選択系
BR9106879A (pt) * 1990-09-25 1993-07-20 Cantab Pharma Res Virus mutuante nao retroviral,uso do mesmo,vacina e processo de manufaturar umvirus mutante

Also Published As

Publication number Publication date
AU690210B2 (en) 1998-04-23
WO1989003429A1 (fr) 1989-04-20
JP2002186494A (ja) 2002-07-02
DE10299049I1 (de) 2004-07-01
AT408549B (de) 2001-12-27
ATA900788A (de) 1995-05-15
NZ225970A (en) 1991-01-29
KR890701757A (ko) 1989-12-21
NL195051C (nl) 2003-07-01
GB2217718A (en) 1989-11-01
CH679934A5 (fr) 1992-05-15
LU90951I2 (fr) 2003-01-15
DE10399031I1 (de) 2004-01-29
IT1229484B (it) 1991-09-03
DE3890874C5 (de) 2005-10-20
JP2002348255A (ja) 2002-12-04
DK175904B1 (da) 2005-06-06
DE3890874C2 (de) 2003-03-13
KR970011149B1 (ko) 1997-07-07
NL300130I2 (nl) 2005-11-01
FR2621487A1 (fr) 1989-04-14
NL300138I2 (nl) 2004-03-01
GB2217718B (en) 1992-05-20
NL300130I1 (nl) 2003-09-01
NL300139I1 (nl) 2004-02-02
JP3348156B2 (ja) 2002-11-20
IL87581A0 (en) 1989-01-31
GB8908921D0 (en) 1989-08-02
NL300138I1 (nl) 2004-02-02
DK203689A (da) 1989-06-27
NL8820679A (nl) 1989-07-03
JP3826055B2 (ja) 2006-09-27
AU2427588A (en) 1989-05-02
BE1002134A5 (fr) 1990-07-24
AU1628895A (en) 1995-08-17
AR241939A1 (es) 1993-01-29
CH679933A5 (fr) 1992-05-15
JPH02500879A (ja) 1990-03-29
LU91039I2 (fr) 2003-11-05
DE10399032I1 (de) 2004-01-29
IT8821772A0 (it) 1988-08-29
DK203689D0 (da) 1989-04-27

Similar Documents

Publication Publication Date Title
FR2621487B1 (fr) Virus avipox recombinant
DK603888A (da) Rekombinant virus
ATA902590A (de) Rekombinantes pockenvirus
DE3853088D1 (de) Rekombinantes Avipoxvirus.
ATA257190A (de) Virales polypeptid
DE3850019D1 (de) Rekombinantes Avipoxvirus.
DK97790D0 (da) Renin-inhiberende peptider
FI892714A0 (fi) Rekombinant-coccidiosisvaccin.
FR2620459B1 (fr) Virus recombinant de la vaccine
DK0517292T3 (da) Rekombinant Avipox-virus
DK353788A (da) Polypeptidderivater
DK551287A (da) Polypeptid
DK354487D0 (da) Oncogen-relaterede peptider
DK531986D0 (da) Peptider
DK377787D0 (da) Interferonfragmenter
DK219187A (da) Rekombinant-virus
MC1830A1 (fr) Peptides
DE3890874T1 (de) Rekombinante avipoxviren
DK596888A (da) Rekombinant lymfotoksin
ZA886415B (en) Recombinant avipox virus
DE3990262T1 (de) Rekombinante retroviren
DK376187D0 (da) Peptider
DK434986D0 (da) Peptider
DK91686D0 (da) Peptider
DK435086D0 (da) Peptider

Legal Events

Date Code Title Description
CP Supplementary protection certificate (spc) filed

Free format text: PRODUCT NAME: VIRUS CANARYPOX RECOMBINANT FELV (VCP97);VIRUS ATTENUE DE LA PANLEUCOPENIE INFECTIEUSE DU CHAT (PLI IV);ANTIGENE DE L HERPESVIRUS FELIN TYPE 1 (C27); ANTIGENE DU CALICIVIRUS FELIN (FCV255); REGISTRATION NO/DATE: EU/2/02/031/001-002 20020308

Spc suppl protection certif: 02C0032

Filing date: 20020904

CR Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)

Free format text: 02C0032, 20020904

CP Supplementary protection certificate (spc) filed
CP Supplementary protection certificate (spc) filed

Free format text: PRODUCT NAME: VIRUS CANARYPOX RECOMBINE GRIPPE A/EQUI-2/KENTUCKY 94; VIRUS CANARYPOX RECOMBINE GRIPPE A/EQUI-2/NEWMARKET/2/93; REGISTRATION NO/DATE: EU/2/03/037/001-004 20030306

Spc suppl protection certif: 03C0032

Filing date: 20030827

Free format text: PRODUCT NAME: VIRUS CANARYPOX RECOMBINE GRIPPE A/EQUI-2/KENTUCKY 94; VIRUS CANARYPOX RECOMBINE GRIPPE A/EQUI-2/NEWMARKET/2/93; ANATOXINE CLOSTRIDIUM TETANI; REGISTRATION NO/DATE: EU/2/03/038/001-004 20030306

Spc suppl protection certif: 03C0031

Filing date: 20030827

CR Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)

Free format text: 03C0032, 20030827

Spc suppl protection certif: 03C0032

Filing date: 20030827

Free format text: 03C0031, 20030827

Spc suppl protection certif: 03C0031

Filing date: 20030827

CP Supplementary protection certificate (spc) filed
CP Supplementary protection certificate (spc) filed

Free format text: PRODUCT NAME: VIRUS RECOMBINANT DE LA GRIPPE AVIAIRE (H5) VECTORISE (VIRUS FOWLPOX); NAT. REGISTRATION NO/DATE: ATVAP 05/017 20060210; FIRST REGISTRATION: FR - ATVAP 05/017 20060210

Spc suppl protection certif: 06C0020

Filing date: 20060626

CR Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)

Free format text: PRODUCT NAME: VIRUS RECOMBINANT DE LA GRIPPE AVIAIRE (H5) VECTORISE (VIRUS FOWLPOX); REGISTRATION NO/DATE IN FRANCE: ATVAP 05/017 DU 20060210; REGISTRATION NO/DATE AT EEC: ATVAP 05/17 DU 20060210

Spc suppl protection certif: 06C0020

Filing date: 20060626

CP Supplementary protection certificate (spc) filed
CY Supplementary certificate of protection granted (eec regulation of 18 june 1992)

Free format text: PRODUCT NAME: VIRUS RECOMBINANT DE LA GRIPPE AVIAIRE (H5) VECTORISE (VIRUS FOWLPOX); REGISTRATION NO/DATE IN FRANCE: ATVAP 05/17 DU 20060210; REGISTRATION NO/DATE AT EEC: ATVAP 05/17 DU 20060210

Spc suppl protection certif: 06C0020

Filing date: 20060626

Extension date: 20130828

CY Supplementary certificate of protection granted (eec regulation of 18 june 1992)

Free format text: PRODUCT NAME: VIRUS CANARYPOX RECOMBINE GRIPPE A/EQUI-/ KENTUCKY/94 + VIRUS CANARYPOX RECOMBINE GRIPPE A/EQUI-2/NEWMARKET2/93; REGISTRATION NO/DATE IN FRANCE: EU/2/03/037/001 DU 20030306; REGISTRATION NO/DATE AT EEC: EU/2/03/307/001-004 DU 20030306

Spc suppl protection certif: 03C0032

Filing date: 20030827

Extension date: 20130828

AV Other action affecting the existence or the validity of an industrial property right

Spc suppl protection certif: 03C0032

CX Request for supplementary protection certificate (spc) rejected

Free format text: PRODUCT NAME: VIRUS CANARYPOX RECOMBINANT FEL V (VCP97); REGISTRATION NO/DATE IN FRANCE: EU/2/02/031/001 DU 20020308; REGISTRATION NO/DATE AT EEC: EU/2/02/031/001-002 DU 20020308

Spc suppl protection certif: 02C0032

Filing date: 20020904

AV Other action affecting the existence or the validity of an industrial property right