YU46091B - Postopek za pripravo derivatov imidazola - Google Patents

Postopek za pripravo derivatov imidazola

Info

Publication number
YU46091B
YU46091B YU215487A YU215487A YU46091B YU 46091 B YU46091 B YU 46091B YU 215487 A YU215487 A YU 215487A YU 215487 A YU215487 A YU 215487A YU 46091 B YU46091 B YU 46091B
Authority
YU
Yugoslavia
Prior art keywords
group
substituted
imidazole derivatives
unsubstituted
procedure
Prior art date
Application number
YU215487A
Other languages
English (en)
Other versions
YU215487A (en
Inventor
J. Mc Garrity
L. Tenud
T. Meul
Original Assignee
Lonza Ag. Gampel Wallis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag. Gampel Wallis filed Critical Lonza Ag. Gampel Wallis
Publication of YU215487A publication Critical patent/YU215487A/xx
Publication of YU46091B publication Critical patent/YU46091B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Dental Preparations (AREA)
  • Liquid Crystal Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Color Printing (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

POSTOPEK ZA PRIPRAVO DERIVATOV IMIDAZOLA, s formulo kjer pomenita Ph fenil in A atom žvepla ali kisika, označen s tem, da tetronsko kislino s formulo kjer ima A navedeni pomen, presnovimo z benzoldiazonijevim halogenidom Ph N2X- v 3-fenilazotetronsko kislino oz. tavtomerni fenilhidrazon s formulo v prisotnosti kislega katalizatorja z alkalijskim nitritom pri 0 do 10В°C, to spojino prevedemo z (R)-ali (S)-1-fenil-etilaminom v prisotnosti Lewisove kisline pri temperaturah od 20 do 120В° C v 3-fenilazo-4-(1-feniletil) amino spojino s formulo azo skupino reduciramo s katalitskim hidriranjem z vodikom ali s presnovo s cinkom v prisotnosti solne ali ocetne kisline in nastalo diamino spojino s formulo prevedemo s fosgensko spojino s formulo YCOZ kjer sta Y in Z enaka ter pomenita klor ali pomeni Y klor in Z alkoksi z 1 do 4 atomi ogljika, feniloksi ali benzil-oksi, v prisotnosti baze pri 0 do 80В° C v končni proizvod. Prijava vsebuje še 2 ovisna zahtevka.
YU215487A 1986-12-02 1987-11-26 Postopek za pripravo derivatov imidazola YU46091B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4790/86A CH671227A5 (sh) 1986-12-02 1986-12-02

Publications (2)

Publication Number Publication Date
YU215487A YU215487A (en) 1989-04-30
YU46091B true YU46091B (sh) 1992-12-21

Family

ID=4282586

Family Applications (1)

Application Number Title Priority Date Filing Date
YU215487A YU46091B (sh) 1986-12-02 1987-11-26 Postopek za pripravo derivatov imidazola

Country Status (20)

Country Link
US (2) US4851540A (sh)
EP (1) EP0270076B1 (sh)
JP (1) JP2560358B2 (sh)
AT (1) ATE68187T1 (sh)
CA (1) CA1322756C (sh)
CH (1) CH671227A5 (sh)
DD (1) DD264696A5 (sh)
DE (1) DE3773625D1 (sh)
DK (1) DK630187A (sh)
ES (1) ES2039227T3 (sh)
FI (1) FI90425C (sh)
GE (1) GEP19970804B (sh)
HU (1) HU198721B (sh)
IE (1) IE61145B1 (sh)
IL (1) IL84590A (sh)
NO (1) NO167922C (sh)
PT (1) PT86258B (sh)
SU (1) SU1549484A3 (sh)
TR (1) TR24505A (sh)
YU (1) YU46091B (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH670644A5 (sh) * 1986-12-18 1989-06-30 Lonza Ag
FI95034C (fi) * 1989-03-15 1995-12-11 Lonza Ag Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi
FI935609A (fi) * 1992-12-18 1994-06-19 Lonza Ag Dihydrofuroimidatsolijohdannaisten asymmetrinen hydraus
EP0647228B1 (en) * 1993-04-20 1996-06-26 Lonza Ltd. Asymmetric hydrogenation of furoimidazole derivatives
CA2122511A1 (en) * 1993-05-14 1994-11-15 John Mcgarrity Asymmetric hydrogenation of furoimidazole derivatives
CA2210821A1 (en) * 1996-09-04 1998-03-04 Lonza Ag Process for the preparation of an arylazotetronic acid derivative
DE19843931A1 (de) * 1997-09-29 1999-04-01 Sumitomo Chemical Co Verfahren zur Herstellung von Hexahydrothieno[3,4-d]imidazol-2,4-dionen
DE10033284A1 (de) * 2000-07-07 2002-01-17 Merck Patent Gmbh Verfahren zur Herstellung von (+)-Biotin
US20030082235A1 (en) * 2001-08-13 2003-05-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Novel reverse thermo-sensitive block copolymers
US20080063620A1 (en) * 2001-08-13 2008-03-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Novel reverse thermo-sensitive block copolymers
CN105418634B (zh) * 2015-12-10 2018-07-10 蚌埠丰原医药科技发展有限公司 生物素中间体杂质的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2489232A (en) * 1949-11-22 Synthesis of biotin
US2489235A (en) * 1947-07-24 1949-11-22 Hoffmann La Roche Synthesis of biotin
JPS463580Y1 (sh) * 1967-06-13 1971-02-06
BE759512A (fr) * 1969-11-29 1971-05-27 Hoffmann La Roche Lactone
US4054740A (en) * 1974-12-24 1977-10-18 Hoffmann-La Roche Inc. Hydroxybiotin
DE3372365D1 (en) * 1982-04-16 1987-08-13 Sumitomo Chemical Co Method of obtaining optically active half esters
DE3580390D1 (de) * 1984-05-18 1990-12-13 Hoffmann La Roche Verfahren zur herstellung eines lactons.
DE3575717D1 (de) * 1984-08-25 1990-03-08 Merck Patent Gmbh Verfahren zur herstellung von (3a5,6ar)-und/oder(3ar,6a5)-1,3-dibenzyl-hexahydro-1h-furo(3,4-d)imidazol-2,4-dion.

Also Published As

Publication number Publication date
JPS63145284A (ja) 1988-06-17
GEP19970804B (en) 1997-01-16
IL84590A0 (en) 1988-04-29
US4851540A (en) 1989-07-25
NO875002D0 (no) 1987-12-01
IE61145B1 (en) 1994-10-05
CH671227A5 (sh) 1989-08-15
PT86258B (pt) 1990-11-07
SU1549484A3 (ru) 1990-03-07
DD264696A5 (de) 1989-02-08
FI875290A0 (fi) 1987-12-01
EP0270076B1 (de) 1991-10-09
PT86258A (de) 1988-01-01
IL84590A (en) 1992-07-15
HUT47285A (en) 1989-02-28
ATE68187T1 (de) 1991-10-15
DK630187A (da) 1988-06-03
FI875290A (fi) 1988-06-03
IE873229L (en) 1988-06-02
US4873339A (en) 1989-10-10
TR24505A (tr) 1991-11-12
DK630187D0 (da) 1987-12-01
FI90425C (fi) 1994-02-10
NO167922B (no) 1991-09-16
NO167922C (no) 1991-12-27
EP0270076A1 (de) 1988-06-08
HU198721B (en) 1989-11-28
NO875002L (no) 1988-06-03
DE3773625D1 (de) 1991-11-14
CA1322756C (en) 1993-10-05
FI90425B (fi) 1993-10-29
ES2039227T3 (es) 1993-09-16
YU215487A (en) 1989-04-30
JP2560358B2 (ja) 1996-12-04

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