YU45735B - Postupak za dobijanje farmaceutskog preparata za primarno davanje u respiratorni trakt - Google Patents

Postupak za dobijanje farmaceutskog preparata za primarno davanje u respiratorni trakt

Info

Publication number
YU45735B
YU45735B YU123885A YU123885A YU45735B YU 45735 B YU45735 B YU 45735B YU 123885 A YU123885 A YU 123885A YU 123885 A YU123885 A YU 123885A YU 45735 B YU45735 B YU 45735B
Authority
YU
Yugoslavia
Prior art keywords
sub
respiratory tract
procedure
obtaining
pharmaceutical preparation
Prior art date
Application number
YU123885A
Other languages
English (en)
Other versions
YU123885A (en
Inventor
B.I. Axelsson
R.L. Brattsand
C.M.O. Dahlback
L.A. Kallstrom
J.W. Trofast
Original Assignee
Aktiebolaget Draco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Draco filed Critical Aktiebolaget Draco
Priority to SI8511238A priority Critical patent/SI8511238A8/sl
Publication of YU123885A publication Critical patent/YU123885A/xx
Publication of YU45735B publication Critical patent/YU45735B/sh
Priority to HR920587A priority patent/HRP920587A2/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

POSTUPAK ZA DOBIJANJE FARMACEUTSKOG PREPARATA ZA PRIMARNO DAVANJE U RESPIRATORNI TRAKT, naznačen time, što obuhvata rastvaranje jedinjenja formule (I) u kojoj je Q i R1 je zasićena ili nezasićena alkil grupa pravog ili račvastog niza sa 11-19 ugljenikovih atoma i R je H, -COCH3, -COC2H5, -CO (CH2)2CH3 ili -CO(CH2)3CH3; i lecitina u organskom rastvaraču kao što je etanol ili hloroform, isparavanje rastvarača i direktno dobivanje lipozoma u vodenoj atmosferi, ili nakon isparavanja, dispergovanje lipidnih slojeva u vodenoj, sa ili bez laktoze, sredini, i mućkanje ili sonifikaciju dobivene suspenzije, ili alternativno, sušenje suspenzije lipozoma. Prijava sadrži još 3 patentna zahteva.
YU123885A 1984-07-30 1985-07-30 Postupak za dobijanje farmaceutskog preparata za primarno davanje u respiratorni trakt YU45735B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI8511238A SI8511238A8 (sl) 1984-07-30 1985-07-30 Postopek za pridobivanje farmacevtskega pripravka za primarno dajanje v respiratorni trakt
HR920587A HRP920587A2 (en) 1984-07-30 1992-10-01 Liposomes containing steroid esters a process for the preparation of stable camomile extract rich with active substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8403905A SE8403905D0 (sv) 1984-07-30 1984-07-30 Liposomes and steroid esters

Publications (2)

Publication Number Publication Date
YU123885A YU123885A (en) 1988-02-29
YU45735B true YU45735B (sh) 1992-07-20

Family

ID=20356623

Family Applications (1)

Application Number Title Priority Date Filing Date
YU123885A YU45735B (sh) 1984-07-30 1985-07-30 Postupak za dobijanje farmaceutskog preparata za primarno davanje u respiratorni trakt

Country Status (29)

Country Link
US (1) US4693999A (sh)
EP (1) EP0170642B1 (sh)
JP (1) JPS6143110A (sh)
KR (1) KR930000045B1 (sh)
AT (1) ATE60990T1 (sh)
AU (1) AU582173B2 (sh)
CA (1) CA1250830A (sh)
CS (1) CS254342B2 (sh)
CY (1) CY1731A (sh)
DD (2) DD248055A5 (sh)
DE (1) DE3581856D1 (sh)
DK (1) DK164509C (sh)
EG (1) EG17462A (sh)
ES (2) ES8704969A1 (sh)
FI (1) FI84914C (sh)
HK (1) HK78293A (sh)
HU (1) HU196827B (sh)
IE (1) IE58074B1 (sh)
IS (1) IS1515B (sh)
NO (1) NO168042C (sh)
NZ (1) NZ212861A (sh)
PH (1) PH21644A (sh)
PL (1) PL145673B1 (sh)
PT (1) PT80884B (sh)
SE (1) SE8403905D0 (sh)
SG (1) SG69093G (sh)
SU (1) SU1493111A3 (sh)
YU (1) YU45735B (sh)
ZA (1) ZA855032B (sh)

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Also Published As

Publication number Publication date
US4693999A (en) 1987-09-15
IE851892L (en) 1986-01-30
CS254342B2 (en) 1988-01-15
SG69093G (en) 1993-08-06
JPS6143110A (ja) 1986-03-01
NO168042C (no) 1992-01-08
NO168042B (no) 1991-09-30
AU4530785A (en) 1986-02-06
DD236535A5 (de) 1986-06-11
PL254681A1 (en) 1986-11-18
DK164509B (da) 1992-07-06
DK336385D0 (da) 1985-07-24
DD248055A5 (de) 1987-07-29
PT80884B (pt) 1987-11-30
AU582173B2 (en) 1989-03-16
DK164509C (da) 1992-11-23
KR930000045B1 (ko) 1993-01-06
FI84914B (fi) 1991-10-31
CY1731A (en) 1994-05-06
ZA855032B (en) 1986-03-26
IE58074B1 (en) 1993-06-30
ES557143A0 (es) 1987-05-16
NZ212861A (en) 1989-01-27
HK78293A (en) 1993-08-13
IS1515B (is) 1992-11-04
SE8403905D0 (sv) 1984-07-30
KR860000863A (ko) 1986-02-20
EP0170642A2 (en) 1986-02-05
SU1493111A3 (ru) 1989-07-07
ES8704969A1 (es) 1987-04-16
EG17462A (en) 1991-03-30
IS3026A7 (is) 1986-01-31
PT80884A (en) 1985-08-01
FI852932L (fi) 1986-01-31
EP0170642A3 (en) 1986-10-29
FI84914C (fi) 1992-02-10
HU196827B (en) 1989-01-30
CA1250830A (en) 1989-03-07
HUT39460A (en) 1986-09-29
DK336385A (da) 1986-01-31
NO852672L (no) 1986-01-31
PL145673B1 (en) 1988-10-31
EP0170642B1 (en) 1991-02-27
PH21644A (en) 1988-01-13
FI852932A0 (fi) 1985-07-29
JPH0459297B2 (sh) 1992-09-21
DE3581856D1 (de) 1991-04-04
ES8705895A1 (es) 1987-05-16
ATE60990T1 (de) 1991-03-15
YU123885A (en) 1988-02-29
ES545651A0 (es) 1987-04-16

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