NO168042B - Analogifremgangsmaate for fremstilling av terapeutisk aktive steroidestere - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive steroidestere Download PDF

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Publication number
NO168042B
NO168042B NO852672A NO852672A NO168042B NO 168042 B NO168042 B NO 168042B NO 852672 A NO852672 A NO 852672A NO 852672 A NO852672 A NO 852672A NO 168042 B NO168042 B NO 168042B
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NO
Norway
Prior art keywords
sub
air flow
air
valve
central body
Prior art date
Application number
NO852672A
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English (en)
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NO168042C (no
NO852672L (no
Inventor
Bengt Ingemar Axelsson
Ralph Lennart Brattsand
Carl Magnus Olof Dahlbaeck
Leif Arne Kaellstroem
Jan William Trofast
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of NO852672L publication Critical patent/NO852672L/no
Publication of NO168042B publication Critical patent/NO168042B/no
Publication of NO168042C publication Critical patent/NO168042C/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Description

Ventil for innblåsing eller utsugning av luft til henholdsvis fra lokaler.
Foreliggende oppfinnelse vedrører en
ventil for innblåsning eller utsugning av
luft til henholdsvis fra lokaler, bestående
av en i tak eller vegger innfelt rektangulær
rørstuss som omfatter en eller flere rektangulære seksjoner.
Ved ventilasjons- og luftkondisjoner-ingsanlegg er det ofte ønskelig å kunne
endre retningen av den luftstrøm som blå-ses inn i lokalet. Hittil har innblåsnings-ventiler enten vært utformet som et gitter
bestående av en ramme med på tvers over
rammeåpningen anbragte plater som rettes
således at luftstrømmen gjennom gitteret
spres vifteformet, eller også har ventilerne
vært utført innstillbar ved at platene er
utformet som spjellblad, som er svingbart
forbunnet langs med sin ene kant. Ved denne siste utformning av platene kan innblås-ningsretningen varieres innen vide grenser
og den gir også ensidig eller dobbeltsidig
innblåsning, dvs. innblåsning på den ene
eller på begge sider av spjellbladene. Disse
sistnevnte kjente typer av innblåsnings-gittere har imidlertid den ulempe at spjellbladene må innstilles individuelt for hvert
innblåsningsalternativ, hvilket i praksis in-nebærer at spjellbladene stilles inn én gang
for alle ved monteringen. Senere foretas
der ingen omstillinger da dette er for om-stendelig. En annen ulempe mot kjente
blåseventiler er at luftstrømmens retning
gjennom ventilen er bestemt av konstruksjonen. Vil man eksempelvis i stedet suge
luften ut gjennom ventilen, må denne er-stattes med en ventil som er konstruert for
den motsatte strømningsretning av luften, bl.a. av hensyn til lydnivået.
Formålet med oppfinnelsen er å opp-nå en enkel omstilling av luftstrømmen fra ventilen og ved en enkel manipulasjon kunne tilpasse konstruksjonen for en end-ret strømningsretning gjennom ventilen. Dette oppnås med en ventil med de i pa-tentpåstand 1 angitte trekk.
Oppfinnelsen skal nu beskrives nær-mere i tilslutning til tegningen, på hvil-ken fig. 1 viser et snitt av en innblåsnings-ventil, fig. 2 viser et snitt av en utsugningsventil og fig. 3 innblåsningsventilen ifølge fig. 1 sett forfra". Ventilen ifølge fig. 1, 2 og 3 består av en i tak eller vegg inn-felte rørstuss 1, som har rektangulært tverrsnitt og en inn mot lokalet vendt åpning 2. I denne rørstuss er et sentralt legeme 3 anordnet svingbart om en til luft-strømmen vinkelrett akse 4. Legemet 3 er utformet med et tverrsnitt som oppviser en mot luftstrømmen vendt avsmalnende og avrundet ende 5 og en fra luftstrømmen vendt bred og på tvers avskåret ende 6. I rørstussens indre er der på to motstående sidevegger anordnet vulster 9, hvis tverrsnitt danner mot hinannen vendende, konvekst buete flater således at der opp-står en venturispalte 7 i rørstussens midte. Ved å svinge legemet 3 om aksen 4 kan luftpassasjene mellom legemet og venturi-spaltens begrensningsflater gis varierende bredde og retning. Luftstrømmen kan av-bøyes i vinkler mellom 0—180° fra åpnin-gens 2 plan. Innblåsningen kan dessuten skje enkeltsidig eller dobbeltsidig alt etter om luften tillates å passere på den ene eller på begge sider av legemet 3. Fig. 1 viser det sentrale legemes stilling ved en enkeltsidig innblåsning fra en veggmontert ventil. Innblåsningsventilen kan med lett-het endres til en utsugningsventil ved at legemet 3 tas ut gjennom åpningen 2 fra den på fig. 1 viste stilling og innføres gjennom rørstussens annen åpning 8, således at dets avsmalehde ende 5 bibeholder sin orientering mot luftstrømmen. For at luft-strømmen og spredning fra innblåsningsventilen skal tilsvare ventilasjonsbehovet, kan der i venturispalten anbringes et for hvert tilfelle formålstjenlig utformet legeme 3. Gjennom å anordne det sentrale legeme på en gjennomgående aksel, kan det lett skiftes ut eller vendes.
Ved en alternativ utførelse kan det sentrale legeme forskyves parallelt med luftstrømmens hovedretning, således at og-så den gjennom ventilen strømmende luft endres. Også en bevegelse av det sentrale legeme vinkelrett til luftstrømmen kan komme på tale, hvis det er ønskelig å bibeholde den totale mengde luft som strøm-mer gjennom og bibeholde luftens retning, men det er ønskelig å endre luftmengden på den ene eller annen side av legemet. Ved disse alternative utførelser forutsettes det dog at akslen er bevegelig parallelt seg selv.

Claims (2)

1. Ventil for innblåsning eller utsugning av luft til henholdsvis fra lokaler, bestående av en i tak eller vegg innfelt rektangulær rørstuss (1) som omfatter en eller flere rektangulære seksjoner, karakterisert ved at vulster (9) hvis tverrsnitt danner mot hinannen vendende, konvekst buede flater, anordnet på to mot hinannen vendte sider av og utgjør indre begrensningsflater for den rektangulære rørstuss, således at seksjonens tverrsnitt danner en venturieformet spalte (7), og at et sentralt legeme (3) er svingbart anordnet i spal-ten om en med vulstenes (9) sylinderakser parallell akse (4), således at der dannes luftpassasjer med innstillbar bredde og retning mellom det sentrale legeme og ven-turispaltens begrensningsflater ved at legemet svinges om sin akse.
2. Ventil i henhold til påstand 1, karakterisert ved at det sentrale legeme har et tverrsnitt som viser en mot luftstrømmen vendt avsmalnende og avrundet ende (5) og en fra luftstrømmen vendt bred og på tvers avskåret ende (6), idet sistnevnte er anordnet til i en første grensestilling å ligge an mot den ene av de sylinderdelformede vulsters bakkant, sett i luftstrømmens retning, og i en annen grensestilling ligge an mot den motstående sylinderdelformede vulsts bakkant.
NO852672A 1984-07-30 1985-07-03 Analogifremgangsmaate for fremstilling av terapeutisk aktive steroidestere NO168042C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8403905A SE8403905D0 (sv) 1984-07-30 1984-07-30 Liposomes and steroid esters

Publications (3)

Publication Number Publication Date
NO852672L NO852672L (no) 1986-01-31
NO168042B true NO168042B (no) 1991-09-30
NO168042C NO168042C (no) 1992-01-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
NO852672A NO168042C (no) 1984-07-30 1985-07-03 Analogifremgangsmaate for fremstilling av terapeutisk aktive steroidestere

Country Status (29)

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US (1) US4693999A (no)
EP (1) EP0170642B1 (no)
JP (1) JPS6143110A (no)
KR (1) KR930000045B1 (no)
AT (1) ATE60990T1 (no)
AU (1) AU582173B2 (no)
CA (1) CA1250830A (no)
CS (1) CS254342B2 (no)
CY (1) CY1731A (no)
DD (2) DD248055A5 (no)
DE (1) DE3581856D1 (no)
DK (1) DK164509C (no)
EG (1) EG17462A (no)
ES (2) ES8704969A1 (no)
FI (1) FI84914C (no)
HK (1) HK78293A (no)
HU (1) HU196827B (no)
IE (1) IE58074B1 (no)
IS (1) IS1515B (no)
NO (1) NO168042C (no)
NZ (1) NZ212861A (no)
PH (1) PH21644A (no)
PL (1) PL145673B1 (no)
PT (1) PT80884B (no)
SE (1) SE8403905D0 (no)
SG (1) SG69093G (no)
SU (1) SU1493111A3 (no)
YU (1) YU45735B (no)
ZA (1) ZA855032B (no)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
SE8506015D0 (sv) * 1985-12-19 1985-12-19 Draco Ab Novel 16,17-acetalsubstituted pregnane 21-oic acid derivatives
SE8601457D0 (sv) * 1986-04-01 1986-04-01 Draco Ab Compositions of liposomes and b?712-receptor active substances for inhalation
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US5690954A (en) * 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
FR2619505B1 (fr) * 1987-08-20 1990-08-31 Dior Christian Parfums Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la pregnenolone ou un ester de pregnenolone, et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite regeneratrice ou revitalisante, l'incorporant
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
EP0397774A1 (en) * 1988-02-04 1990-11-22 Board Of Regents, The University Of Texas System Formulation and use of retinoids in treatment of cancer and other diseases
US4906476A (en) * 1988-12-14 1990-03-06 Liposome Technology, Inc. Novel liposome composition for sustained release of steroidal drugs in lungs
US5043165A (en) * 1988-12-14 1991-08-27 Liposome Technology, Inc. Novel liposome composition for sustained release of steroidal drugs
WO1990006775A1 (en) * 1988-12-14 1990-06-28 Liposome Technology, Inc. A novel nonphospholipid liposome composition for sustained release of drugs
US5100662A (en) * 1989-08-23 1992-03-31 The Liposome Company, Inc. Steroidal liposomes exhibiting enhanced stability
US6146657A (en) * 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
US6551576B1 (en) 1989-12-22 2003-04-22 Bristol-Myers Squibb Medical Imaging, Inc. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5922304A (en) 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US5542935A (en) 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5469854A (en) * 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US6001335A (en) * 1989-12-22 1999-12-14 Imarx Pharmaceutical Corp. Contrasting agents for ultrasonic imaging and methods for preparing the same
US5776429A (en) * 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US5888995A (en) * 1991-02-04 1999-03-30 Astra Aktiebolag Steroid esters
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
SE9100342D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroid esters
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US5874062A (en) * 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
FR2675146A1 (fr) * 1991-04-10 1992-10-16 Roussel Uclaf Nouveaux derives sterouides de la pregna-1,4-diene-3,20-dione, leur preparation, leur application a la preparation de derives 16,17-methylene dioxy substitues et nouveaux intermediaires.
CZ171095A3 (en) * 1993-01-08 1996-01-17 Astra Ab Novel steroidal derivatives specific for colon or ilium
WO1994028876A1 (en) * 1993-06-07 1994-12-22 Advanced Therapies, Inc. Liposome powders
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
US5635206A (en) * 1994-01-20 1997-06-03 Hoffmann-La Roche Inc. Process for liposomes or proliposomes
CH689139A5 (de) * 1995-04-03 1998-10-30 Cerbios Pharma Sa Verfahren zur Herstellung einer liposomalen, in Wasser dispergierbaren, oral zu verabreichenden, festen, trockenen therapeutischen Formulierung.
US5997898A (en) * 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
US6231834B1 (en) 1995-06-07 2001-05-15 Imarx Pharmaceutical Corp. Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6139819A (en) * 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US6033645A (en) * 1996-06-19 2000-03-07 Unger; Evan C. Methods for diagnostic imaging by regulating the administration rate of a contrast agent
CA2252617A1 (en) 1996-05-01 1997-11-06 Imarx Pharmaceutical Corp. Methods for delivering compounds into a cell
US5958378A (en) * 1996-07-03 1999-09-28 Research Development Foundation High dose liposomal aerosol formulations containing cyclosporin A or budesonide
TW497974B (en) * 1996-07-03 2002-08-11 Res Dev Foundation High dose liposomal aerosol formulations
US6414139B1 (en) 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
DE69718519T2 (de) * 1996-09-11 2003-11-06 Imarx Pharmaceutical Corp., Tucson Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
US6143276A (en) * 1997-03-21 2000-11-07 Imarx Pharmaceutical Corp. Methods for delivering bioactive agents to regions of elevated temperatures
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US6090800A (en) * 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
WO1998050041A1 (en) * 1997-05-06 1998-11-12 Imarx Pharmaceutical Corp. Novel prodrugs comprising fluorinated amphiphiles
US6416740B1 (en) 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US6548047B1 (en) 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
US6123923A (en) * 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
EP1955700B9 (en) 1999-09-30 2011-09-07 Harbor BioSciences, Inc. Therapeutic treatment of androgen receptor driven conditions
US20040009229A1 (en) * 2000-01-05 2004-01-15 Unger Evan Charles Stabilized nanoparticle formulations of camptotheca derivatives
WO2001049268A1 (en) * 2000-01-05 2001-07-12 Imarx Therapeutics, Inc. Pharmaceutical formulations for the delivery of drugs having low aqueous solubility
DE10116197A1 (de) * 2001-03-30 2002-10-17 Bernina Biosystems Gmbh Neue Methylprednisolonderivate mit therapeutischer Wirkung
WO2003070745A2 (en) 2002-02-20 2003-08-28 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids
US20050009798A1 (en) 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
EP1487413A4 (en) * 2002-03-05 2010-11-10 Transave Inc INHALATION SYSTEM FOR THE TREATMENT OF INTRACELLULAR INFECTIONS
WO2004033478A2 (en) * 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
AU2003304204B2 (en) * 2002-10-29 2009-12-24 Insmed Incorporated Sustained release of antiinfectives
WO2005016352A1 (en) * 2003-08-05 2005-02-24 Sepracor Inc. AMINO ACID AND PEPTIDE-MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH ß2 ADRENERGIC AGONISTS
AU2006322076C1 (en) 2005-12-08 2013-11-14 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections
NO331891B1 (no) * 2007-03-20 2012-04-30 Clavis Pharma Asa Kjemiske forbindelser, et farmasoytisk preparat inneholdende slike forbindelser, samt anvendelse derav for behandling av kreft, inflammasjon og KOLS
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
AU2013266400B2 (en) 2012-05-21 2017-06-22 Insmed Incorporated Systems for treating pulmonary infections
RU2018135921A (ru) 2012-11-29 2019-02-05 Инсмед Инкорпорейтед Стабилизированные составы ванкомицина
LT3466432T (lt) 2014-05-15 2020-12-28 Insmed Incorporated Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti
KR101961484B1 (ko) * 2016-01-08 2019-03-22 최규선 생콩 탈피장치
EP3773505A4 (en) 2018-03-30 2021-12-22 Insmed Incorporated PROCESS FOR THE CONTINUOUS MANUFACTURING OF LIPOSOMAL MEDICINAL PRODUCTS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE378109B (no) * 1972-05-19 1975-08-18 Bofors Ab
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
CH621479A5 (no) * 1977-08-05 1981-02-13 Battelle Memorial Institute
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
HU182775B (en) * 1981-10-15 1984-03-28 Richter Gedeon Vegyeszet Process for preparing new 3-chloro-pregnane derivatives
DE3228629A1 (de) * 1982-07-31 1984-02-02 Reifenrath, Rainer Richard Otto, Dr., 3104 Unterlüß Pharmazeutisches erzeugnis zur behandlung der atemwege und verfahren zu seiner herstellung
GB2135647A (en) * 1983-02-15 1984-09-05 Squibb & Sons Inc Method of preparing liposomes and products produced thereby

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AU4530785A (en) 1986-02-06
SU1493111A3 (ru) 1989-07-07
DK336385A (da) 1986-01-31
JPH0459297B2 (no) 1992-09-21
AU582173B2 (en) 1989-03-16
NZ212861A (en) 1989-01-27
KR860000863A (ko) 1986-02-20
HUT39460A (en) 1986-09-29
HU196827B (en) 1989-01-30
ES8705895A1 (es) 1987-05-16
ATE60990T1 (de) 1991-03-15
PH21644A (en) 1988-01-13
DE3581856D1 (de) 1991-04-04
CS254342B2 (en) 1988-01-15
JPS6143110A (ja) 1986-03-01
HK78293A (en) 1993-08-13
US4693999A (en) 1987-09-15
KR930000045B1 (ko) 1993-01-06
PL254681A1 (en) 1986-11-18
FI852932L (fi) 1986-01-31
FI84914C (fi) 1992-02-10
SG69093G (en) 1993-08-06
IS3026A7 (is) 1986-01-31
EG17462A (en) 1991-03-30
EP0170642A2 (en) 1986-02-05
CY1731A (en) 1994-05-06
NO168042C (no) 1992-01-08
EP0170642B1 (en) 1991-02-27
DK164509C (da) 1992-11-23
EP0170642A3 (en) 1986-10-29
PT80884B (pt) 1987-11-30
IS1515B (is) 1992-11-04
ES8704969A1 (es) 1987-04-16
SE8403905D0 (sv) 1984-07-30
IE58074B1 (en) 1993-06-30
DD248055A5 (de) 1987-07-29
IE851892L (en) 1986-01-30
FI852932A0 (fi) 1985-07-29
ES557143A0 (es) 1987-05-16
ES545651A0 (es) 1987-04-16
ZA855032B (en) 1986-03-26
NO852672L (no) 1986-01-31
PL145673B1 (en) 1988-10-31
CA1250830A (en) 1989-03-07
PT80884A (en) 1985-08-01
DD236535A5 (de) 1986-06-11
FI84914B (fi) 1991-10-31
YU123885A (en) 1988-02-29
YU45735B (sh) 1992-07-20
DK336385D0 (da) 1985-07-24
DK164509B (da) 1992-07-06

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