YU30194A - Postupak za pripremanje biorazgradljivih poliestarskih mikročestica i njihova primena - Google Patents

Postupak za pripremanje biorazgradljivih poliestarskih mikročestica i njihova primena

Info

Publication number
YU30194A
YU30194A YU30194A YU30194A YU30194A YU 30194 A YU30194 A YU 30194A YU 30194 A YU30194 A YU 30194A YU 30194 A YU30194 A YU 30194A YU 30194 A YU30194 A YU 30194A
Authority
YU
Yugoslavia
Prior art keywords
microparticles
preparation
polyester
procedure
application
Prior art date
Application number
YU30194A
Other languages
English (en)
Inventor
S.L. Craft
H.T. Ferguson
L.M. Heiman
W.W. Thompson
Original Assignee
Eli Lilly Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/168,941 external-priority patent/US5635216A/en
Application filed by Eli Lilly Company filed Critical Eli Lilly Company
Publication of YU30194A publication Critical patent/YU30194A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/25Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

POSTUPAK ZA PRIPREMANJE BIORAZGRADLJIVIH POLIESTARSKIH MIKROČESTICA I NJIHOVA PRIMENA - opisan je postupak za pripremanje biorazgradljivih poliestarskih mikročestica koje sadrže bioaktivne polipeptidne agense, koji obuhvata rastvaranje poliestra u organskom rastvaraču, dodavanje biološki aktivnog agensa u rastvor, emulgovanje dobijene suspenzije, isparavanje rastvarača iz emulzije radi dobijanja mikročestice i sakupljanje mikročestica. Smeše poliestarskih mikrocestica obuhvataju biokompatibilne, biorazgradljive mikročestice sa poliestarskom matricom i od oko 5 do oko 25 mas. % bioloSki aktivnog, vodo-rastvornog polipeptidi spergovanog u matrici, koji je odabran iz grupe koju čine faktor oslobađanja hormona rasta i njegovi sintetički analogoni i njegovi farmakološko aktivni delovi.
YU30194A 1993-05-27 1994-05-25 Postupak za pripremanje biorazgradljivih poliestarskih mikročestica i njihova primena YU30194A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6841393A 1993-05-27 1993-05-27
US08/168,941 US5635216A (en) 1993-12-16 1993-12-16 Microparticle compositions containing peptides, and methods for the preparation thereof

Publications (1)

Publication Number Publication Date
YU30194A true YU30194A (sh) 1997-01-08

Family

ID=26748947

Family Applications (1)

Application Number Title Priority Date Filing Date
YU30194A YU30194A (sh) 1993-05-27 1994-05-25 Postupak za pripremanje biorazgradljivih poliestarskih mikročestica i njihova primena

Country Status (13)

Country Link
EP (1) EP0628307A2 (sh)
JP (1) JPH0797314A (sh)
CN (1) CN1097984A (sh)
AU (1) AU6329894A (sh)
BR (1) BR9402078A (sh)
CA (1) CA2124277A1 (sh)
CZ (1) CZ125994A3 (sh)
HU (1) HUT75467A (sh)
IL (1) IL109730A0 (sh)
NO (1) NO941938L (sh)
NZ (1) NZ260577A (sh)
PE (1) PE12995A1 (sh)
YU (1) YU30194A (sh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105123601B (zh) * 2014-05-28 2018-02-27 贵州梦润鹌鹑有限公司 一种鹌鹑蛋的孵化方法

Also Published As

Publication number Publication date
CZ125994A3 (en) 1994-12-15
NO941938D0 (no) 1994-05-25
CN1097984A (zh) 1995-02-01
EP0628307A2 (en) 1994-12-14
AU6329894A (en) 1994-12-01
HU9401579D0 (en) 1994-09-28
NZ260577A (en) 1996-01-26
BR9402078A (pt) 1994-12-13
IL109730A0 (en) 1994-08-26
NO941938L (no) 1994-11-28
HUT75467A (en) 1997-05-28
JPH0797314A (ja) 1995-04-11
CA2124277A1 (en) 1994-11-28
PE12995A1 (es) 1995-05-18

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