YU278780A - Process for preparing a cyclic hexapeptide compound - Google Patents

Process for preparing a cyclic hexapeptide compound

Info

Publication number
YU278780A
YU278780A YU02787/80A YU278780A YU278780A YU 278780 A YU278780 A YU 278780A YU 02787/80 A YU02787/80 A YU 02787/80A YU 278780 A YU278780 A YU 278780A YU 278780 A YU278780 A YU 278780A
Authority
YU
Yugoslavia
Prior art keywords
preparing
cyclic hexapeptide
hexapeptide compound
compound
cyclic
Prior art date
Application number
YU02787/80A
Other languages
English (en)
Inventor
R M Freidinger
R D Veber
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/089,827 external-priority patent/US4235886A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of YU278780A publication Critical patent/YU278780A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
YU02787/80A 1979-10-31 1980-10-30 Process for preparing a cyclic hexapeptide compound YU278780A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8982879A 1979-10-31 1979-10-31
US06/089,827 US4235886A (en) 1979-10-31 1979-10-31 Cyclic hexapeptide somatostatin analogs

Publications (1)

Publication Number Publication Date
YU278780A true YU278780A (en) 1983-01-21

Family

ID=26780979

Family Applications (1)

Application Number Title Priority Date Filing Date
YU02787/80A YU278780A (en) 1979-10-31 1980-10-30 Process for preparing a cyclic hexapeptide compound

Country Status (17)

Country Link
EP (1) EP0029310B1 (no)
KR (1) KR860001961B1 (no)
AU (1) AU540140B2 (no)
CA (1) CA1216844A (no)
DD (1) DD153684A5 (no)
DE (1) DE3064499D1 (no)
DK (1) DK152505C (no)
ES (1) ES8202787A1 (no)
FI (1) FI74711C (no)
GR (1) GR70725B (no)
IE (1) IE50364B1 (no)
NO (1) NO150958C (no)
NZ (1) NZ195303A (no)
PL (1) PL128347B1 (no)
PT (1) PT71966B (no)
RO (1) RO81523A (no)
YU (1) YU278780A (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4360516A (en) * 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs
US4374060A (en) * 1981-07-15 1983-02-15 Merck & Co., Inc. Process for the preparation of cyclic hexapeptide
US4427661A (en) * 1982-07-30 1984-01-24 Merck & Co., Inc. Fluorinated cyclic hexapeptide somatostatin analogs
DE3379657D1 (en) * 1982-12-06 1989-05-24 Merck & Co Inc Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them
DE3303345A1 (de) * 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Cyclische peptide mit somatostatin-wirkung
US4505897A (en) * 1983-04-18 1985-03-19 The Administrators Of The Tulane Educational Fund Cyclic pentapeptides displaying somatostatin antagonism and method of treatment of mammals therewith
US5620675A (en) 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
EP1099707A3 (en) * 1993-06-23 2002-01-09 Diatide, Inc. Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
MY147327A (en) 1995-06-29 2012-11-30 Novartis Ag Somatostatin peptides
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7708136L (sv) * 1976-08-02 1978-02-03 Merck & Co Inc Cykliska hexapeptider
EP0000053B1 (en) * 1977-06-08 1981-05-27 Merck & Co. Inc. Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden

Also Published As

Publication number Publication date
AU6358180A (en) 1981-05-07
KR830004223A (ko) 1983-07-09
DD153684A5 (de) 1982-01-27
ES496424A0 (es) 1982-02-16
ES8202787A1 (es) 1982-02-16
DK460580A (da) 1981-05-01
DK152505B (da) 1988-03-07
NO803245L (no) 1981-05-04
EP0029310A1 (en) 1981-05-27
RO81523B (ro) 1983-07-30
RO81523A (ro) 1983-08-03
FI74711C (fi) 1988-03-10
DK152505C (da) 1988-07-25
PT71966B (en) 1982-03-31
IE50364B1 (en) 1986-04-02
PT71966A (en) 1980-11-01
NZ195303A (en) 1984-10-19
DE3064499D1 (en) 1983-09-08
NO150958C (no) 1985-01-16
IE802224L (en) 1981-04-30
EP0029310B1 (en) 1983-08-03
GR70725B (no) 1983-01-18
FI74711B (fi) 1987-11-30
PL128347B1 (en) 1984-01-31
FI803306L (fi) 1981-05-01
NO150958B (no) 1984-10-08
CA1216844A (en) 1987-01-20
PL227577A1 (no) 1981-10-02
KR860001961B1 (ko) 1986-11-05
AU540140B2 (en) 1984-11-01

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