YU27002A - Derivati aromatičnih di-ketona, postupci za njihovu izradu i njihova upotreba kao farmaceutskih poizvoda - Google Patents

Derivati aromatičnih di-ketona, postupci za njihovu izradu i njihova upotreba kao farmaceutskih poizvoda

Info

Publication number
YU27002A
YU27002A YU27002A YUP27002A YU27002A YU 27002 A YU27002 A YU 27002A YU 27002 A YU27002 A YU 27002A YU P27002 A YUP27002 A YU P27002A YU 27002 A YU27002 A YU 27002A
Authority
YU
Yugoslavia
Prior art keywords
derivatives
production
pharmaceutical
aromativ
processes
Prior art date
Application number
YU27002A
Other languages
English (en)
Inventor
Laszlo Vertesy
Michael Kurz
Erich Paulus
Original Assignee
Aventis Pharma Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh. filed Critical Aventis Pharma Deutschland Gmbh.
Publication of YU27002A publication Critical patent/YU27002A/sh
Publication of RS50431B publication Critical patent/RS50431B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Ovaj pronalazak se odnosi na nove derivate aromatičnih di-ketona i njihove farmaceutski prihvatljive soli, estre, etre i druge očigledne hemijske ekvivalente. Derivati su inhibitori glukozo-6-fosfet translokaze i mogu se koristiti u lečenju dijabetes mellitusa. Ovaj pronalazak se dalje odnosi na postupak za izradu derivata, upotrebu derivata i njihovih farmaceutski prihvatljivih soli, estara, etara i drugih očiglednih hemijskih ekvivalenata kao farmaceutskih preparata, posebno na njihovu upotrebu u lečenju dijabetes mellitusa i na farmaceutske kompozicije koje uključuju derivate, farmaceutski prihvatljive soli, estre, etre i druge njihove očigledne hemijske ekvivalente.[The present invention relates to new aromatic di-keto derivatives and to their pharmaceutically acceptable salts, esters, ethers and other obvious chemical equivalents. The derivatives are glucose-6-phosphate translocase inhibitors and can be used in the treatment of diabetes mellitus. The present invention further relates to a process for the production of the derivatives, to the use of the derivatives and their pharmaceutically acceptable salts, esters, ethers and other obvious chemical equivalents as pharmaceuticals, in particular to their use in the treatment of diabetes mellitus, and to pharmaceutical compositions comprising the derivatives, pharmaceutically acceptable salts, esters, ethers or other obvious chemical equivalents thereof.
YUP-270/02A 1999-10-25 2000-08-19 Derivati aromatičnih di-ketona, postupci za njihovu izradu i njihova upotreba kao farmaceutskih proizvoda RS50431B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99121241 1999-10-25

Publications (2)

Publication Number Publication Date
YU27002A true YU27002A (sh) 2005-06-10
RS50431B RS50431B (sr) 2009-12-31

Family

ID=8239274

Country Status (24)

Country Link
US (1) US6380257B1 (sh)
EP (1) EP1248763B1 (sh)
JP (1) JP2003512448A (sh)
KR (1) KR100755730B1 (sh)
CN (1) CN1192999C (sh)
AR (1) AR034095A1 (sh)
AU (1) AU779352B2 (sh)
BR (1) BR0015023A (sh)
CA (1) CA2388957C (sh)
CZ (1) CZ20021404A3 (sh)
EE (1) EE200200216A (sh)
HK (1) HK1049827B (sh)
HR (1) HRP20020352A2 (sh)
HU (1) HUP0203129A3 (sh)
IL (1) IL149156A0 (sh)
NO (1) NO20021812L (sh)
NZ (1) NZ518545A (sh)
PL (1) PL205217B1 (sh)
RS (1) RS50431B (sh)
RU (1) RU2252211C2 (sh)
SK (1) SK287428B6 (sh)
TR (1) TR200201124T2 (sh)
WO (1) WO2001030736A2 (sh)
ZA (1) ZA200203034B (sh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10208828A1 (de) * 2002-03-01 2003-09-11 Bayer Ag Verfahren zur Reduktion von 3-Heteroaryl-3-oxopropionsäurederivaten
KR101106152B1 (ko) * 2010-05-14 2012-01-20 (주)한국킹유전자 주야 변환형 사인보드

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW255880B (sh) * 1992-09-09 1995-09-01 Hoechst Ag
TW399041B (en) 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
JP2000514493A (ja) 1996-07-15 2000-10-31 モービル・オイル・コーポレーション 吹込成形およびフィルム用途用コモノマー前処理２金属系触媒
AR012449A1 (es) * 1997-04-18 2000-10-18 Hoechst Marion Roussell Deutschland Gmbh Kodaistatinas a, b, c y d, proceso para su produccion, y su uso.
DE19740080A1 (de) * 1997-09-12 1999-03-18 Hoechst Marion Roussel De Gmbh Neue Phthalaldehyd-Derivate, Verfahren zu deren Herstellung und deren Verwendung
KR20010071564A (ko) * 1998-06-24 2001-07-28 로버트 흐라이탁, 미쉘 베스트 뭄베이스타틴, 이의 제조방법 및 약제로서의 이의 용도

Also Published As

Publication number Publication date
RU2252211C2 (ru) 2005-05-20
HK1049827A1 (en) 2003-05-30
HK1049827B (zh) 2005-09-02
BR0015023A (pt) 2002-06-18
KR20020047262A (ko) 2002-06-21
PL205217B1 (pl) 2010-03-31
AU779352B2 (en) 2005-01-20
CA2388957C (en) 2009-01-06
KR100755730B1 (ko) 2007-09-06
HUP0203129A3 (en) 2003-12-29
SK287428B6 (sk) 2010-09-07
AU7278200A (en) 2001-05-08
IL149156A0 (en) 2002-11-10
WO2001030736A2 (en) 2001-05-03
CN1379752A (zh) 2002-11-13
EP1248763A2 (en) 2002-10-16
HUP0203129A2 (hu) 2003-01-28
NO20021812L (no) 2002-05-14
SK5442002A3 (en) 2002-12-03
HRP20020352A2 (en) 2004-02-29
EP1248763B1 (en) 2014-06-25
NO20021812D0 (no) 2002-04-17
US6380257B1 (en) 2002-04-30
AR034095A1 (es) 2004-02-04
TR200201124T2 (tr) 2002-09-23
EE200200216A (et) 2003-06-16
CZ20021404A3 (cs) 2002-07-17
PL354452A1 (en) 2004-01-12
RS50431B (sr) 2009-12-31
ZA200203034B (en) 2002-11-21
CN1192999C (zh) 2005-03-16
CA2388957A1 (en) 2001-05-03
NZ518545A (en) 2004-07-30
JP2003512448A (ja) 2003-04-02
WO2001030736A3 (en) 2001-11-01

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