YU178790A - Novi benzopiranon-beta-d-tioksilozidi i postupak za njihovo dobijanje - Google Patents

Novi benzopiranon-beta-d-tioksilozidi i postupak za njihovo dobijanje

Info

Publication number
YU178790A
YU178790A YU178790A YU178790A YU178790A YU 178790 A YU178790 A YU 178790A YU 178790 A YU178790 A YU 178790A YU 178790 A YU178790 A YU 178790A YU 178790 A YU178790 A YU 178790A
Authority
YU
Yugoslavia
Prior art keywords
group
atom
beta
benzopyranone
substituents
Prior art date
Application number
YU178790A
Other languages
English (en)
Other versions
YU47867B (sh
Inventor
S. Samreth
V. Barberousse
P. Renaut
F. Bellamy
J. Millet
Original Assignee
Fournier Industrie Et Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8912452A external-priority patent/FR2652353B1/fr
Priority claimed from FR9003401A external-priority patent/FR2659659B1/fr
Application filed by Fournier Industrie Et Sante filed Critical Fournier Industrie Et Sante
Priority to HRP-1787/90A priority Critical patent/HRP920811B1/xx
Publication of YU178790A publication Critical patent/YU178790A/sh
Publication of YU47867B publication Critical patent/YU47867B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones

Abstract

NOVI BENZOPIRANON-BETA-D-TIOKSILOZIDI I POSTUPAK ZA NJIHOVO DOBIJANJE. Predmetni pronalazak se odnosi na nove industrijske proizvode, jedinjenja benzopiranon-beta-D-tioksilozide formule: u kojoj: jedan od supstituenata R ili R' predstavlja atom kiseonika dvostruko vezan na ciklični ugljenik a drugi predstavlja grupu R1, simbol - predstavlja dvostruku konjugovanu vezu na grupi CO predstavljenu sa jednim od supstituenata R ili R', X predstavlja atom sumpora ili kiseonika, R1 i R2, identični ili različiti predstavljaju svaki atom vodonika, grupu C1-4 alkil, atom halogena, trifluorometil ili fenil grupu, R1 i R2 razmatrani zajedno, mogu da grade sa benzopiranon grupom na koju su vezani, grupu 7,8,9,10-tetrahidrodibenzo/b,d/piran-6-on ili 1,2,3,4-tetrahidro-9H-9H-ksanten-9-on, i Y predstavlja atom vodonika ili alifatičnu acil grupu. Ova jedinjenja su korisna terapeutski uglavnom kao antitrombotski venski agensi.
YU178790A 1989-09-22 1990-09-20 Novi benzopiran-2-on-beta-d-tioksilozidi i postupak za njihovo dobijanje YU47867B (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HRP-1787/90A HRP920811B1 (en) 1989-09-22 1992-10-02 New benzophyranone-beta-d-thioxilozides, method for the preparation and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8912452A FR2652353B1 (fr) 1989-09-22 1989-09-22 Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
FR9003401A FR2659659B1 (fr) 1990-03-16 1990-03-16 Nouveaux benzopyran-4-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.

Publications (2)

Publication Number Publication Date
YU178790A true YU178790A (sh) 1992-12-21
YU47867B YU47867B (sh) 1996-02-19

Family

ID=26227568

Family Applications (1)

Application Number Title Priority Date Filing Date
YU178790A YU47867B (sh) 1989-09-22 1990-09-20 Novi benzopiran-2-on-beta-d-tioksilozidi i postupak za njihovo dobijanje

Country Status (24)

Country Link
US (1) US5169838A (sh)
EP (1) EP0421829B1 (sh)
JP (1) JPH07103147B2 (sh)
KR (1) KR0142670B1 (sh)
CN (1) CN1027268C (sh)
AT (1) ATE113956T1 (sh)
AU (2) AU631456B2 (sh)
CA (1) CA2024476C (sh)
DE (1) DE69014064T2 (sh)
DK (1) DK0421829T3 (sh)
ES (1) ES2066165T3 (sh)
FI (1) FI100183B (sh)
GR (1) GR3014966T3 (sh)
HR (1) HRP920811B1 (sh)
HU (1) HU207867B (sh)
IE (1) IE65092B1 (sh)
IL (1) IL95582A (sh)
NO (1) NO172987C (sh)
NZ (1) NZ245783A (sh)
PT (1) PT95369B (sh)
RU (1) RU1838323C (sh)
SK (1) SK463890A3 (sh)
UA (1) UA13476A (sh)
YU (1) YU47867B (sh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2801055B1 (fr) * 1999-11-17 2002-02-08 Fournier Ind & Sante Derives de beta-d-5-thioxylose, procede de preparation et utilisation en therapeutique
FR2824559B1 (fr) * 2001-05-11 2004-02-13 Fournier Lab Sa Nouveaux derives 5-thio-beta-xylopyronasides, procede de preparation, compositions pharmaceutiques les contenant et leur utilisation en therapeutique
FR2846966A1 (fr) * 2002-11-07 2004-05-14 Fournier Lab Sa Derive du 4-methyl-2-oxo-2h-1-benzopyran-7-yl 5-thio-beta-d- xylopyranoside, son procede de preparation et composition pharmaceutique le contenant
CN1802372B (zh) * 2003-06-11 2010-05-12 麦克弗罗斯特加拿大有限公司 7＇-(1,3-噻唑-2-基)-硫代香豆素及其作为白三烯生物合成抑制剂的应用
FR2860234B1 (fr) * 2003-09-25 2005-12-23 Fournier Lab Sa Nouveaux derives 666 du thioxylose
TW200640449A (en) * 2005-02-18 2006-12-01 Smithkline Beecham Corp Pharmaceutical compositions and methods
FR2903698B1 (fr) * 2006-07-13 2009-01-30 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose.
FR2906248B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
FR2906247B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
US20090075914A1 (en) * 2007-09-13 2009-03-19 Protia, Llc Deuterium-enriched odiparcil
CN101397315B (zh) * 2007-09-24 2013-08-07 中国医学科学院药物研究所 香豆素苷类化合物、其制法和其药物组合物与用途
US10092540B2 (en) 2013-10-04 2018-10-09 Inventiva Method of treatment of a mucopolysaccharidosis
FR3011468B1 (fr) 2013-10-04 2015-12-04 Inventiva Utilisation de l'odiparcil dans le traitement d'une mucopolysaccharidose

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034306A1 (de) * 1970-07-10 1972-01-20 Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof 2 (3,4 Dimethyl-cumarin 7 yl) oxy alkylcarbonsaure Derivate und Verfahren zu ihrer Herstellung
FR2492830A1 (fr) * 1980-10-29 1982-04-30 Sori Soc Rech Ind Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique
JPS6013788A (ja) * 1983-07-05 1985-01-24 Yamanouchi Pharmaceut Co Ltd 新規なクマリン誘導体
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
US4681954A (en) * 1985-10-07 1987-07-21 Pennwalt Corporation 7,8,9,10-tetrahydro-6-oxo-6H-dibenzo(b,d)pyranyloxy-propanes
FR2614893B1 (fr) * 1987-05-04 1989-12-22 Fournier Innovation Synergie Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
AU2539792A (en) 1992-11-26
GR3014966T3 (en) 1995-05-31
IL95582A0 (en) 1991-06-30
KR0142670B1 (ko) 1998-07-01
HU906005D0 (en) 1991-03-28
SK280827B6 (sk) 2000-08-14
DK0421829T3 (da) 1995-01-16
NO904088D0 (no) 1990-09-19
ATE113956T1 (de) 1994-11-15
HRP920811B1 (en) 1998-12-31
YU47867B (sh) 1996-02-19
PT95369B (pt) 1997-06-30
CN1027268C (zh) 1995-01-04
EP0421829A1 (fr) 1991-04-10
CA2024476C (en) 1999-10-12
NO172987C (no) 1993-10-06
US5169838A (en) 1992-12-08
DE69014064D1 (de) 1994-12-15
FI904614A0 (fi) 1990-09-19
JPH03120292A (ja) 1991-05-22
UA13476A (uk) 1997-04-25
NO172987B (no) 1993-06-28
IE65092B1 (en) 1995-10-04
PT95369A (pt) 1991-05-22
NZ245783A (en) 1993-07-27
HUT55794A (en) 1991-06-28
RU1838323C (ru) 1993-08-30
FI100183B (fi) 1997-10-15
AU6253190A (en) 1991-03-28
EP0421829B1 (fr) 1994-11-09
AU631456B2 (en) 1992-11-26
DE69014064T2 (de) 1995-05-18
SK463890A3 (en) 2000-08-14
IE903414A1 (en) 1991-04-10
AU642829B2 (en) 1993-10-28
JPH07103147B2 (ja) 1995-11-08
ES2066165T3 (es) 1995-03-01
HRP920811A2 (en) 1995-10-31
KR910006283A (ko) 1991-04-29
CN1050544A (zh) 1991-04-10
IL95582A (en) 2001-06-14
CA2024476A1 (en) 1991-03-23
HU207867B (en) 1993-06-28
NO904088L (no) 1991-03-25

Similar Documents

Publication Publication Date Title
YU178790A (sh) Novi benzopiranon-beta-d-tioksilozidi i postupak za njihovo dobijanje
AR003955A1 (es) Derivados de n-(indol-2-carbonil)-glicinamidas, procedimiento para su obtencion y composiciones que los contienen.
ATE153025T1 (de) Triazolopyrimidinderivate mit fungizider aktivität
FI96309B (fi) Menetelmä farmakologisesti arvokkaiden fuusioituneiden polysyklisten yhdisteiden valmistamiseksi
ZA883031B (en) Novel b-d-phenyl-thioxylosides,their method of preparation and their use as therapeutics
DE60020587D1 (de) Zwischenprodukte für die herstellung von 5- nitro- benzofuran oder benzothiophenderivaten und ihre verwendungen
IT1230595B (it) Perossiacidi immido derivati
ATE130007T1 (de) Sulphonylphenyl-beta-d-thioxyloside, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
ES535357A0 (es) Un metodo de preparar espiro-(benzofuran-azalcanos)
GR1001309B (el) Μεθοδος παρασκευης παραγωγου ενωσεως της διχλωροανιλινης.
ATE134625T1 (de) Alphamethylen-5-thiazoloessigsäurederivate, zwischenprodukte und verfahren zur herstellung, ihre anwendung als fongizide und diese enthaltende zusammensetzungen
ES2053621T3 (es) Un procedimiento para preparar ciertas oxazolonas triciclicas cardiotonicas.
FR2566407B1 (fr) Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant