YU106890A - Postopek za pripravo p-substituiranih propan-fosfinskih kislin - Google Patents
Postopek za pripravo p-substituiranih propan-fosfinskih kislinInfo
- Publication number
- YU106890A YU106890A YU106890A YU106890A YU106890A YU 106890 A YU106890 A YU 106890A YU 106890 A YU106890 A YU 106890A YU 106890 A YU106890 A YU 106890A YU 106890 A YU106890 A YU 106890A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- hydrogen
- hydroxy
- group
- aliphatic
- amino
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000000949 anxiolytic effect Effects 0.000 abstract 1
- 229940005530 anxiolytics Drugs 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000002664 nootropic agent Substances 0.000 abstract 1
- 230000001777 nootropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/36—Amides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
POSTOPEK ZA PRIPRAVO P-SUBSTITUIRANIH PROPAN-FOSFINSKIH KISLIN. Spojine s formulo I kjer je bodisi R1 halogen, R1' halogen ali vodik ter R2 in R2' pomenita vodik ali R1 in R1' predstavljata vodik, R2 je alifatski ali aromatski ostanek in R2' hidroksi ali R2 in R2' skupaj predstavljata okso in kjer R pomeni alifatski, cikloalifatski, cikloalifatsko-alifatski ali aralifatski ostanek z 2 ali več atomi ogljika ali, če R1 in R1' označujeta vodik, R2 predstavlja aromatski ostanek in je R2' hidroksi, R predstavlja metil, in njihove soli so koristne kot nootropiki, antidepresivi in/ali anksiolitiki. Lahko jih pripravimo z nadomestitvijo katerekoli skupine R5 z vodikom in/ali pretvorbo katerekoli skupine Z0 v amino v spojini s formulo II kjer imajo R, R1, R1', R2 in R2' prejšnje promene, Z predstavlja zaščiteno ali latentno amino skupino Z0 in R4 pomeni vodik ali hidroksi-zaščitno skupino R5 in kjer je lahko amino kot sestavni del R in/ali hidroksi R2' ali okso R2 + R2' prisoten v začasno zaščiteni obliki.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898912814A GB8912814D0 (en) | 1989-06-03 | 1989-06-03 | P-substituted propane-phospinic acid compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU106890A true YU106890A (sh) | 1992-07-20 |
Family
ID=10657847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU106890A YU106890A (sh) | 1989-06-03 | 1990-05-31 | Postopek za pripravo p-substituiranih propan-fosfinskih kislin |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0402312B1 (sh) |
| JP (1) | JPH0320288A (sh) |
| KR (1) | KR910000766A (sh) |
| AT (1) | ATE117693T1 (sh) |
| AU (1) | AU633577B2 (sh) |
| CA (1) | CA2018036A1 (sh) |
| DD (1) | DD294945A5 (sh) |
| DE (1) | DE69016270T2 (sh) |
| DK (1) | DK0402312T3 (sh) |
| ES (1) | ES2067717T3 (sh) |
| FI (1) | FI95263C (sh) |
| GB (1) | GB8912814D0 (sh) |
| HU (1) | HU207335B (sh) |
| IE (1) | IE65155B1 (sh) |
| IL (1) | IL94537A (sh) |
| MX (1) | MX20962A (sh) |
| NO (1) | NO177675C (sh) |
| NZ (1) | NZ233915A (sh) |
| PT (1) | PT94244B (sh) |
| YU (1) | YU106890A (sh) |
| ZA (1) | ZA904203B (sh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8728483D0 (en) * | 1987-12-04 | 1988-01-13 | Ciba Geigy Ag | Chemical compounds |
| EP0767174A1 (de) * | 1991-11-21 | 1997-04-09 | Ciba-Geigy Ag | Neue Aminoalkanphosphinsäuren und ihre Salze |
| DE19604195C1 (de) | 1996-02-06 | 1997-04-17 | Hoechst Ag | Verfahren zur Herstellung von Phosphonigsäuremonoalkylestern |
| EP1095050A1 (de) | 1998-07-15 | 2001-05-02 | Hassan Jomaa | Phosphororganische verbindungen und ihre verwendung |
| SE0102055D0 (sv) * | 2001-06-08 | 2001-06-08 | Astrazeneca Ab | New Compounds |
| DE102008056341A1 (de) * | 2008-11-07 | 2010-05-12 | Clariant International Limited | Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2032712C3 (de) * | 1970-07-02 | 1978-10-19 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von w-Amino-alkanphosphonsäure bzw.- phosphinsäurederivaten |
| GB8728483D0 (en) * | 1987-12-04 | 1988-01-13 | Ciba Geigy Ag | Chemical compounds |
| GB8820266D0 (en) * | 1988-08-26 | 1988-09-28 | Smith Kline French Lab | Compounds |
-
1989
- 1989-06-03 GB GB898912814A patent/GB8912814D0/en active Pending
-
1990
- 1990-05-25 DE DE69016270T patent/DE69016270T2/de not_active Expired - Fee Related
- 1990-05-25 DK DK90810387.2T patent/DK0402312T3/da active
- 1990-05-25 ES ES90810387T patent/ES2067717T3/es not_active Expired - Lifetime
- 1990-05-25 AT AT90810387T patent/ATE117693T1/de active
- 1990-05-25 EP EP90810387A patent/EP0402312B1/en not_active Expired - Lifetime
- 1990-05-28 IL IL9453790A patent/IL94537A/en unknown
- 1990-05-31 DD DD90341208A patent/DD294945A5/de not_active IP Right Cessation
- 1990-05-31 YU YU106890A patent/YU106890A/sh unknown
- 1990-05-31 AU AU56161/90A patent/AU633577B2/en not_active Ceased
- 1990-05-31 MX MX2096290A patent/MX20962A/es unknown
- 1990-06-01 ZA ZA904203A patent/ZA904203B/xx unknown
- 1990-06-01 CA CA002018036A patent/CA2018036A1/en not_active Abandoned
- 1990-06-01 PT PT94244A patent/PT94244B/pt not_active IP Right Cessation
- 1990-06-01 IE IE198090A patent/IE65155B1/en not_active IP Right Cessation
- 1990-06-01 NO NO902449A patent/NO177675C/no unknown
- 1990-06-01 FI FI902749A patent/FI95263C/fi not_active IP Right Cessation
- 1990-06-01 HU HU903299A patent/HU207335B/hu not_active IP Right Cessation
- 1990-06-01 NZ NZ233915A patent/NZ233915A/en unknown
- 1990-06-02 KR KR1019900008137A patent/KR910000766A/ko not_active Application Discontinuation
- 1990-06-04 JP JP2144591A patent/JPH0320288A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI95263B (fi) | 1995-09-29 |
| NO902449D0 (no) | 1990-06-01 |
| IL94537A0 (en) | 1991-03-10 |
| IL94537A (en) | 1994-11-28 |
| IE65155B1 (en) | 1995-10-04 |
| FI902749A0 (fi) | 1990-06-01 |
| DD294945A5 (de) | 1991-10-17 |
| IE901980L (en) | 1990-12-03 |
| FI95263C (fi) | 1996-01-10 |
| PT94244A (pt) | 1991-02-08 |
| AU633577B2 (en) | 1993-02-04 |
| NO902449L (no) | 1990-12-04 |
| ZA904203B (en) | 1991-02-27 |
| HUT54169A (en) | 1991-01-28 |
| CA2018036A1 (en) | 1990-12-03 |
| JPH0320288A (ja) | 1991-01-29 |
| NO177675C (no) | 1995-11-01 |
| KR910000766A (ko) | 1991-01-30 |
| NO177675B (no) | 1995-07-24 |
| GB8912814D0 (en) | 1989-07-19 |
| AU5616190A (en) | 1990-12-06 |
| ATE117693T1 (de) | 1995-02-15 |
| NZ233915A (en) | 1992-07-28 |
| EP0402312A3 (en) | 1991-04-03 |
| HU903299D0 (en) | 1990-10-28 |
| EP0402312A2 (en) | 1990-12-12 |
| ES2067717T3 (es) | 1995-04-01 |
| DE69016270D1 (de) | 1995-03-09 |
| MX20962A (es) | 1994-02-28 |
| HU207335B (en) | 1993-03-29 |
| PT94244B (pt) | 1997-03-31 |
| DE69016270T2 (de) | 1995-06-08 |
| EP0402312B1 (en) | 1995-01-25 |
| DK0402312T3 (da) | 1995-02-27 |
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