WO2023098148A1

WO2023098148A1 - Westergren-method-based fully automatic erythrocyte sedimentation rate dynamic analyzer and measurement method

Info

Publication number: WO2023098148A1
Application number: PCT/CN2022/113611
Authority: WO
Inventors: 蔡泳; 马江; 刘勇; 杨光涛; 谢健
Original assignee: 重庆南方数控设备股份有限公司
Priority date: 2021-12-01
Filing date: 2022-08-19
Publication date: 2023-06-08
Also published as: CN114184528A

Abstract

A Westergren-method-based fully automatic erythrocyte sedimentation rate dynamic analyzer and a measurement method. The analyzer mainly comprises: a transmission device (100) for placing a blood sample to be subjected to measurement, wherein the transmission device (100) comprises a turntable which is provided with several holes (123) for placing the blood sample; a sample injection device (200) for sucking the blood sample into a Westergren erythrocyte sedimentation rate glass tube (310), wherein the blood sample enters the Westergren erythrocyte sedimentation rate glass tube (310) through a sample injection syringe (220), a valve group, and a silicone tube connected to the Westergren erythrocyte sedimentation rate glass tube (310); a measurement device for measuring the liquid level of the blood sample in the Westergren erythrocyte sedimentation rate glass tube (310); and a cleaning device for cleaning and blow-drying the Westergren erythrocyte sedimentation rate glass tube (310) after testing. The analyzer and the measurement method can improve the working efficiency, reduce biological hazards, facilitate cleaning, and achieve accurate readings and a simple operation.

Description

A kind of Wei's method automatic erythrocyte sedimentation rate dynamic analyzer and detection method

technical field

The invention relates to the technical field of automatic blood detection instruments, in particular to a full-automatic erythrocyte sedimentation dynamic analyzer and a detection method using Wei's method.

Background technique

After the blood is added with anticoagulant, it is placed in a special glass tube, and the distance that red blood cells descend within a certain period of time is measured, which is called erythrocyte sedimentation rate, or ESR for short. Erythrocyte sedimentation rate is a traditional and widely used index, which is usually used as a tool for the diagnosis and treatment of certain diseases, such as inflammatory diseases, autoimmune diseases, hyperglobulinemia, hypercholesterolemia, malignant tumors, etc. a reference standard. The International Committee for Standardization of Blood designated the Widmansler method as the gold standard for erythrocyte sedimentation rate detection, and the sedimentation results were read after 1 hour of natural sedimentation using standard Widmanner tubes.

Currently, the Widmanner's method of ESR on the market is mainly operated manually, which is cumbersome and has low work efficiency, large errors in manual interpretation, biological hazards, and difficult cleaning.

Contents of the invention

(1) Purpose of the invention

In view of the above problems, the object of the present invention is to propose a fully automatic erythrocyte sedimentation dynamic analyzer and detection method using the Wei's method, which can improve work efficiency, provide accurate readings, and be easy to operate, reduce biological hazards, and facilitate cleaning. The present invention discloses the following technical solutions .

(2) Technical solutions

As the first aspect of the present invention, the present invention discloses a kind of Wei's method automatic erythrocyte sedimentation dynamic analyzer, comprising:

A transmission device, the transmission device is used to place the blood sample to be tested, and the turntable of the transmission device is provided with several holes for placing the blood sample;

Sampling device, the sampling device is used to draw the blood sample into the Widman's ESR tube, and the blood sample enters the Wei's ESR tube through the injection needle, the valve group and the silicone tube connected to the Wei's ESR tube. In the erythrocyte sedimentation glass tube;

A detection device, the detection device is used to detect the liquid level of the blood sample in the Widman's erythrocyte sedimentation glass tube;

A cleaning device, the cleaning device is used for cleaning and drying the Wilcoxon ESR glass tube after the test.

In a possible implementation manner, the sampling device includes a first moving mechanism, the first moving mechanism drives the sampling needle to slide up and down, and is used to fix the lower part of the bracket of the first moving mechanism A needle washer is provided, and the needle washer is used for cleaning the sampling needle.

In a possible implementation manner, the detection device includes a second moving mechanism and a detection plate, and the second moving mechanism drives the detection plate to move linearly along the axial direction of the Wilcox ESR tube. A sensor is arranged on the detection board, and the sensor is used for detecting the height of the blood sample in the Wilcox ESR tube.

In a possible implementation manner, the cleaning mechanism includes a cleaning pump, a transition cylinder, and a cleaning solution bucket, one end of the cleaning pump communicates with the Wilcox ESR tube, and the other end communicates with the fluid outlet of the transition cylinder. The mouth is connected, and the liquid inlet of the transition cylinder is connected with the cleaning liquid bucket;

The drying mechanism includes an air blowing pump, one end of the air blowing pump is communicated with the Wilcox ESR tube, and the other end is communicated with the atmosphere.

In a possible implementation manner, a heating element is provided in the transition cylinder, and the heating element is used to heat the cleaning liquid in the transition cylinder to a set temperature.

In a possible implementation manner, the transmission device includes a first drive mechanism and a turntable mechanism;

The turntable mechanism includes a first turntable and a second turntable, the first turntable is used to place blood sample test tubes, the second turntable is arranged below the first turntable, and the upper surface of the second turntable is in contact with the test tube Bottom abutment, used to accept test tubes;

The first driving mechanism drives the turntable mechanism to rotate so that the holes are located directly below the sample feeding device.

In a possible implementation manner, the dynamic analyzer further includes a waste liquid collection bucket, the waste liquid collection bucket is arranged on one side of the dynamic analyzer, and is used for storing the waste liquid after cleaning the Widmanscher ESR tubes. fluid and blood samples after the test.

As the second aspect of the present invention, the present invention also discloses a detection method of a Weissman's method automatic erythrocyte sedimentation dynamic analyzer described in any of the above technical solutions, including the following steps:

Use the sampling needle to draw the blood sample into the Weisser's ESR tube;

performing multiple detections on the liquid level of the blood sample in the Wilcox ESR tube;

The blood sample after the test is recovered, and the Wilcox ESR glass tube is cleaned.

In a possible implementation manner, the drawing of the blood sample into the Weisserman's ESR tube by using a sampling needle also includes:

Place the blood sample test tubes in turn on the holes of the turntable according to the rules;

Utilize the transmission device to rotate the turntable to rotate the blood sample test tube to the right below the sampling device.

Use the detection board to detect whether the blood sample has reached the set height in the Weisser's ESR tube.

(3) Beneficial effects

A Wei's method automatic erythrocyte sedimentation dynamic analyzer and detection method disclosed by the present invention have the following beneficial effects:

Inhale the blood sample placed on the turntable into the standard Widgers ESR tube through the sampling needle, and block the lower end of the standard Widgers ESR tube through the electromagnetic pinch valve for the channel in the valve group, so that the blood sample is naturally in the Widgers ESR tube. Settling, at the same time, the detection board scans the liquid level in the standard Widgers ESR tube several times within 1 hour, and accurately reads the liquid surface sedimentation height. After the test is completed, the blood sample in the standard Widgers ESR tube passes through the waste liquid tube of the transmission device It is discharged into the waste liquid collection barrel, and at the same time, the cleaning liquid is heated by the cleaning liquid heating device and injected into the standard Widmansler ESR tube for cleaning, and then the standard Widgers ESR tube is dried by the air blowing pump in the pump unit; the electromagnetic clamp The tube valve clamps the silicone tube at the lower end of the silicone Wilcoxon ESR tube to prevent the backflow of blood samples; multiple samples can be placed in the turntable, and different channels can be switched through the rotary valve to draw blood samples for simultaneous testing to improve detection efficiency.

Description of drawings

The embodiments described below with reference to the accompanying drawings are exemplary and are intended to explain and describe the present invention, but should not be construed as limiting the protection scope of the present invention.

Fig. 1 is a kind of Wei's method automatic erythrocyte sedimentation dynamic analyzer three-dimensional structure schematic diagram disclosed by the present invention;

Fig. 2 is a schematic diagram of pipeline connections of various mechanisms disclosed by the present invention;

Fig. 3 is a schematic structural view of the sample injection device disclosed in the present invention;

Fig. 4 is a schematic structural view of the detection device disclosed in the present invention;

5 is a schematic structural view of the cleaning device disclosed in the present invention;

Fig. 6 is a structural schematic diagram of a transition cylinder disclosed by the present invention;

Fig. 7 is a detection method of a fully automatic erythrocyte sedimentation dynamic analyzer disclosed by the present invention.

Reference signs: 100, transmission device; 110, first driving mechanism; 120, turntable mechanism; 121, first turntable; 122; second turntable; 123, hole position; 200, sampling device; 210, first moving mechanism ; 220, sampling needle; 230, needle washer; 240, photoelectric sensor; 250, sampling pump; 300, photosensitive detection plate; Transition cylinder; 413, cleaning liquid bucket; 414, heating element; 415, temperature sensor; 420, blowing pump; 900, upper rotary valve; 910, lower rotary valve; 920, three-way valve; 930, pinch valve; 940, Tap; 950, public connector; 960, waste liquid collection bucket; 970, waste liquid cylinder; 980, first sampling needle cleaning pump; 990, second sampling needle waste liquid pump.

Detailed ways

In order to make the objectives, technical solutions and advantages of the present invention clearer, the technical solutions in the embodiments of the present invention will be described in more detail below in conjunction with the drawings in the embodiments of the present invention.

It should be noted that: in the drawings, the same or similar symbols represent the same or similar elements or elements with the same or similar functions. The described embodiments are part of the embodiments of the present invention, but not all of the embodiments. In the case of no conflict, the embodiments in the present application and the features in the embodiments can be combined with each other. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

In describing the present invention, it is to be understood that the terms "central", "longitudinal", "transverse", "front", "rear", "left", "right", "vertical", "horizontal", The orientations or positional relationships indicated by "top", "bottom", "inner", "outer", etc. are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying The devices or elements referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore should not be construed as limiting the scope of the invention.

The first embodiment of a fully automatic erythrocyte sedimentation dynamic analyzer disclosed by the present invention will be described in detail below with reference to FIGS. 1-6 . This embodiment is mainly applied to blood testing, which can improve work efficiency, provide accurate readings, and be easy to operate, reduce biological hazards, and facilitate cleaning.

As shown in Figures 1-6, this embodiment mainly includes a transmission device 100, a sample feeding device 200, a detection device and a cleaning device, wherein the turntable of the transmission device 100 is provided with several holes 123 for placing blood samples, Put the test tube of the blood sample to be tested in the hole 123 for placing the blood sample test tube, and the sampling device 200 is used for sucking the blood sample into the Wilcox ESR tube 310, and the blood sample passes through the sampling needle 220, the valve group and the The silicone tube connected to the Wirmanser ESR tube 310 enters the Wirmanser ESR tube 310, the detection device is used to detect the liquid level of the blood sample in the Wirmanser ESR tube 310, and the cleaning device is used to clean the blood samples after the test. The Wilcox ESR tube 310 is cleaned and dried.

The working principle of the automatic erythrocyte sedimentation rate analyzer of the present application is as follows: through the sampling needle 220 of the sampling device 200, the blood sample placed on the turntable is sucked into the standard Werner's erythrocyte sedimentation glass tube 310, and the The electromagnetic pinch valve 930 of the channel blocks the lower end of the standard Widgner's ESR tube, allowing the blood sample to settle naturally in the Widgers ESR tube 310, and at the same time, the detection plate adjusts the liquid level in the standard Widgers ESR tube 310 several times within 1 hour. Scanning is performed to accurately read the liquid surface sedimentation height. After the test is completed, the blood sample in the standard Widgers ESR tube 310 is discharged into the waste liquid collection barrel 960 through the waste liquid cylinder 970 of the transmission device 100, and the cleaning liquid is passed through the cleaning device at the same time. After heating, it is poured into the standard Widgers ESR tube 310 for cleaning, and then the standard Widgers ESR tube 310 is blown dry by the blowing pump 420 in the pump unit.

As shown in Fig. 2, in a possible embodiment, the automatic erythrocyte sedimentation rate dynamic analyzer by Wei's method also includes a valve group, a pump group, a waste liquid collection bucket 960 and connecting pipelines, wherein the valve group includes The upper rotary valve 900 and the lower rotary valve 910 at both ends of the erythrocyte sedimentation glass tube 310, the three-way valve 920 arranged at the communication position of each component, and the pinch valve 930 at the end of the Wermann's erythrocyte sedimentation glass tube 310; the pump set includes a sample pump 250, blowing pump 420, sampling pump 250, cleaning pump 411, the first sampling needle cleaning pump 980 and the second sampling needle waste liquid pump 990; Communication and common joint 950 and tap joint 940; waste liquid collection barrel 960 is arranged on one side of the instrument, and is used for collecting the cleaning liquid and the blood sample after the test.

In a possible embodiment, one end of the Wilcox ESR tube 310 communicates with the upper rotary valve 900 through the tap 940, and the other end communicates with the lower rotary valve 910 through the pinch valve 930 and the tap 940, and the lower rotary valve 910 One end of the tap 940 away from the tap is communicated with one end of the common joint 950, and the other end of the common joint 950 is communicated with the pipeline.

As shown in FIG. 1 , in a possible embodiment, the transmission device 100 is used to place blood samples to be tested, and the turntable of the transmission device 100 is provided with several holes 123 for placing blood samples. Wherein the transmission device 100 includes a first drive mechanism 110 and a turntable mechanism 120, the turntable mechanism 120 includes a first turntable 121 and a second turntable 122, the first turntable 121 is used to place blood sample test tubes, and the second turntable 122 is arranged on the first turntable 121 Below, and the upper surface of the second turntable 122 abuts against the bottom surface of the test tube for receiving the test tube, wherein the first turntable 121 is uniformly provided with several holes 123 for placing blood sample test tubes along the circumferential direction of the first turntable 121 , the distance between the second turntable 122 and the first turntable 121 is no more than one-third of the height of the test tube, the second turntable 122 is fixedly connected with the first turntable 121 through several connecting rods, and the second turntable 122 is connected along the second turntable. Positioning holes are uniformly arranged on the circumference of the turntable, and the position and quantity of the positioning holes correspond to the position and quantity of the hole positions 123 one by one. The turntable mechanism 120 also includes a rotating shaft for supporting the first rotating disk 121 and the second rotating disk 122, one end of the rotating shaft passes through the center of the second rotating disk 122 and is fixedly connected to the lower surface of the first rotating disk 121, and the other end of the rotating shaft is connected to the first rotating disk 121. The driving mechanism 110 is fixedly connected, and the first driving mechanism 110 drives the rotating shaft to rotate, thereby realizing the rotation of the turntable mechanism 120 .

The first driving mechanism 110 includes a driving motor and a synchronous belt, wherein the rotating shaft is fixedly connected with the driven wheel of the synchronous belt, the output shaft of the driving motor is fixedly connected with the driving wheel of the synchronous belt, the driving motor drives the driving wheel to rotate, and the driven wheel is driven by the synchronous belt Rotate, the driven wheel drives the slave shaft to rotate, thereby realizing the rotation of the turntable mechanism 120 .

Further, the first driving mechanism 110 may adopt any mechanism or component that can drive the rotating shaft to rotate.

Further, each hole position 123 is provided with a number, and the number can be a number or a letter number, and a combination of numbers and letters can be used. The numbers correspond one-to-one, and the blood sample in the test tube is sucked into the Wilcox ESR tube 310 with the same number as the hole position 123 of the test tube through the sampling device 200, which is convenient for determining the number of the blood sample, and comparing the test result with the number Correspondence, which is convenient for recording, tracking, storing and finding information.

Further, a positioning mechanism is provided below the sampling device 200, and the positioning mechanism can be a sensor or a label. Through the positioning mechanism, it can be confirmed whether the code of the current hole position 123 is consistent with the code of the Wilcox ESR tube 310.

Further, in this application, the first turntable 121 is provided with 40 holes 123 .

As shown in FIG. 3 , in a possible implementation, the sampling device 200 is used to draw a blood sample into a Widgers ESR tube 310 . The sampling device 200 includes a sampling needle 220, a first moving mechanism 210, and a needle washer 230. The first moving mechanism 210 drives the sampling needle 220 to move closer to and away from the test tube. When the sampling needle 220 is in a position away from the test tube, The needle washer 230 is located at the end of the sampling needle 220, and the sampling needle 220 is located at the center of the needle washer 230. When the sampling needle 220 completes a sampling, the sampling needle 220 is cleaned.

The first moving mechanism 210 includes a first driving motor and a timing belt. The end of the sampling needle 220 away from the needle washer 230 is fixedly connected to the timing belt. The first driving motor drives the driving shaft of the timing belt to rotate, and the active rotation drives the timing belt to move, thereby The sampling needle 220 can move up and down along the axial direction of the sampling needle 220 , and at the same time, a photoelectric sensor 240 is provided on the first moving mechanism 210 for detecting the position of the sampling needle 220 .

As shown in FIG. 4 , in a possible implementation manner, the detection device is used to detect the liquid level of the blood sample in the Widgers ESR tube 310 . The detection device includes a second moving mechanism and a detection plate, and the second moving mechanism drives the detection plate to perform multiple reciprocating linear motions along the axial direction of the Wilcox ESR glass tube 310, wherein the second mechanism includes a second drive motor, a lead screw and a The screw nut fixed by the detection board is provided with a slide block, and the frame is provided with a chute that limits the rotation of the slide block along the axis of the screw. The combination of the lead screw and the screw nut makes the rotary motion into a linear motion, thereby driving the detection board to move.

Furthermore, the second moving mechanism can adopt any structure such as rack and pinion, hydraulic transmission, etc. that can realize multiple reciprocating linear motions of the detection plate along the axial direction of the Widman's ESR tube 310 .

Further, the detection board can be the photosensitive detection board 300 , or a sensor that detects the position of the liquid level such as infrared rays.

As shown in FIG. 5 , in a possible implementation manner, the cleaning device is used to clean and dry the Wilcox ESR tube 310 after the test.

Further, the cleaning device includes a cleaning mechanism 400 and a drying mechanism, wherein the cleaning mechanism 400 includes a cleaning pump 411, a transition cylinder 412, and a cleaning liquid bucket 413. One end of the cleaning pump 411 communicates with the upper rotary valve 900, and the other end communicates with the transition cylinder through a valve. The liquid outlet of 412 is connected, and the liquid inlet of the transition cylinder 412 is connected with the cleaning liquid barrel 413 . The drying mechanism includes a blowing pump 420, one end of the blowing pump 420 communicates with the upper rotary valve 900, and the other end communicates with the atmosphere.

As shown in Figure 6, further, a heating element 414 and a temperature sensor 415 are also provided in the transition cylinder 412, and the cleaning liquid in the transition cylinder 412 is heated by the heating element 414, and the temperature sensor 415 detects that the temperature of the cleaning liquid reaches the set point. When the temperature is set, a signal is sent to the controller, which turns off the heating element 414.

Further, the cleaning liquid in the cleaning liquid bucket 413 is injected into the transition cylinder 412 through the first sampling needle cleaning pump 980 and the sampling needle 220.

In this application, the specific detection process is as follows:

1. The process of placing test samples: place all the test tubes of blood samples to be tested on the holes of the first turntable, and the first driving mechanism rotates the turntable mechanism to turn the turntable to the hole with the same code as the current Wilcox ESR tube, so that The hole position is located directly under the sampling device, waiting for the sampling device to suck the blood sample in the current test tube.

2. Sampling process: the first moving mechanism controls the downward movement of the sampling needle, so that the sampling needle is inserted into the test tube with the same number as the Widman's ESR tube, the lower rotary valve and the pinch valve are opened, and the blood is passed through the sampling device. The sample enters the Widgers ESR tube through the silicone tube connected with the sampling needle and the Wiltshire ESR tube. When the photosensitive detection board detects that the liquid level of the blood sample in the Wiltshire ESR tube reaches the set height, the first movement The mechanism controls the upward movement of the sampling needle, stops the suction of samples, and at the same time closes the pinch valve, and completes the sampling of a Wilcox ESR tube.

The transmission device drives the turntable to rotate, and the blood sample test tube at the next hole position is rotated to the bottom of the sampling device, and the above sampling process is repeated, and blood samples are sucked into other Widgers ESR glass tubes until all the blood samples on the turntable are sucked into the Widgers ESR tubes. Inside the glass tube.

3. Test process: The blood sample naturally settles in the Wei's erythrocyte sedimentation glass tube for 1 hour. During this period, the second moving mechanism drives the photosensitive detection plate to perform multiple up and down reciprocating movements according to the preset time interval. The liquid level height in the ESR glass tube;

4. Cleaning stage: after the test, insert the sampling needle into the waste liquid cylinder, open the lower rotary valve, then open the three-way valve SF1, the three-way valve SF3 and the upper rotary valve, and use the cleaning pump to clean the waste liquid in the transition cylinder. The heated cleaning solution is injected into the Widmanner ESR glass tube to rinse the inside of the Widgers ESR glass tube, wherein the cleaning solution used for washing and the discarded blood sample are inserted into the waste liquid tube through the injection needle and discharged from the external waste liquid tube to collect.

After flushing, close the three-way valve SF1, turn on the three-way valve SF2 and the blowing pump, and use the blowing pump to pump high-pressure gas into the Widgers ESR tube to blow away the residual liquid from the inner arm of the Widgers ESR tube to the inner wall of the injection needle. drop.

The following describes in detail with reference to FIG. 7 . Based on the same inventive concept, the embodiment of the present invention also provides a first embodiment of a detection method for a fully automatic erythrocyte sedimentation dynamic analyzer using the Weiss method. Since the principle of the problem solved by this method is similar to that of the above-mentioned automatic erythrocyte sedimentation dynamic analyzer by Wei's method, the products applicable to this method can refer to the above-mentioned automatic erythrocyte sedimentation dynamic analyzer by Wei's method, and the repetition is no longer repeat. This embodiment is mainly applied to blood testing, which can improve work efficiency, provide accurate readings, and be easy to operate, reduce biological hazards, and facilitate cleaning.

As shown in Figure 7, this embodiment mainly includes the following steps:

S600. Using the sampling needle to suck the blood sample into the Weisserman's ESR tube.

In step S600, the blood sample is sucked into the Weisserman's ESR tube by using the sampling needle, which also includes:

The transmission device is used to rotate the turntable to rotate the blood sample test tube directly under the sampling device.

In step S600, the blood sample is sucked into the Weisserman's erythrocyte sedimentation glass tube by using a sampling needle, and then it also includes:

S610. Use the detection board to detect whether the blood sample has reached the set height in the Widgers ESR tube.

Further, first place the test tube containing the blood sample on the corresponding hole in the turntable of the transmission device, start the transmission device, the transmission device drives the turntable to rotate and rotate the test tube in the corresponding hole position directly below the sampling device, and secondly, inject the sample The sampling needle of the device moves downwards and is inserted into the test tube to draw the blood sample into the Weisser ESR tube.

Further, the blood sample enters the Widmanner ESR tube through the silicone tube connected to the lower rotary valve and the Widgers ESR tube through the injection needle. Stop sampling, and block the lower end of the Widmanner ESR tube through the electromagnetic pinch valve for the silicone tube channel in the valve group to prevent the backflow of the blood sample and allow the blood sample to settle naturally in the Widgers ESR tube.

Further, the blood sample in the test tube is not less than the blood sample in the Weisser ESR tube.

Further, the turntable can be provided with 1-40 holes, and the test tubes are placed according to predetermined specifications.

Further, after the last blood sample is inhaled into the Widman's erythrocyte sedimentation glass tube, the transmission device drives the turntable to rotate, and the blood sample test tube at the next hole position is rotated directly under the sampling device, and the sampling device performs repeated sampling actions. By switching different channels through the rotary valve to draw blood samples for simultaneous testing, the detection efficiency can be improved.

Further, the Weisserman's ESR tubes are all provided with numbers corresponding to the hole positions of the turntable, so the blood sample drawn by the sampling needle is sucked into the corresponding Weisserman's ESR tube from the blood sample in the test tube with the same numerical label. .

Further, the Widmanner ESR tubes used in this application are standard Widmanner ESR tubes.

S700, performing multiple detections on the liquid level height of the blood sample in the Widman's erythrocyte sedimentation glass tube.

In step S700, the blood sample naturally settles in the Wiltshire erythrocyte sedimentation glass tube for 1 hour, and during the 1 hour of sedimentation, the photosensitive detection board detects the blood sample in the Wiltshire erythrocyte sedimentation glass tube according to the preset time interval. The liquid level is scanned multiple times to accurately read the liquid surface settlement height to ensure the accuracy of the test results.

Further, after the detection board scans the height of the liquid level of the blood sample in the Wilcox ESR tube each time, the height value is sent to the processing device, and the processing device records and stores the height value, and after the detection is completed, according to the height Numerical mapping of time and height curves and analysis of test results.

S800. Recover the blood sample after the test, and clean the Wiltshire ESR tube.

In step 800, after the detection is completed, the blood sample in the Widmansler ESR tube is discharged into the waste liquid collection barrel through the waste liquid cylinder of the transmission device, and then the heated cleaning solution is sucked into the Wirmann ESR tube by the cleaning mechanism , inject the blood sample in the corresponding Weissern ESR glass tube through the upper rotary valve to rinse the blood sample in the test tube, and run downward through the sampling needle of the sampling device, insert it into the waste liquid cylinder on the transmission device, and the waste liquid after washing passes through The lower rotary valve, the sampling needle, the waste liquid cartridge and the second sampling needle waste pump are discharged into the external waste liquid collection bucket.

Use the air blowing pump of the blowing mechanism to pump high-pressure gas into the Wilcox ESR glass tube to blow away the residual liquid droplets from the inner wall of the test tube to the inner wall of the sampling needle.

Further, the silicone tube is connected to the external cleaning solution barrel, and the cleaning mechanism is used to suck the cleaning solution into the Widgers ESR tube.

Further, the waste liquid cylinder is connected to the external waste liquid collection bucket through a silicone tube.

The detection method of this application is: the blood sample placed on the turntable is sucked into the standard Widmansler ESR tube through the sampling needle of the sampling device, and the lower end of the standard Widmanner ESR tube is blocked by the electromagnetic pinch valve for the channel in the valve group , let the blood sample settle naturally in the Wiltshire ESR tube, and at the same time, the detection board scans the liquid level in the standard Wiltshire ESR tube several times within 1 hour to accurately read the liquid surface sedimentation height. The blood sample in the tube is discharged into the waste liquid collection barrel through the waste liquid cylinder of the transmission device, and at the same time, the cleaning liquid is heated by the cleaning liquid heating device and then injected into the standard Wilcoxon ESR glass tube for cleaning, and then the air blowing pump in the pump unit is used to clean the standard tube. Widmans ESR glass tubes are blown dry, and multiple samples can be placed in the turntable, and different channels are switched through the rotary valve to draw blood samples for simultaneous testing to improve detection efficiency.

The above is only a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Anyone skilled in the art can easily think of changes or substitutions within the technical scope disclosed in the present invention. All should be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention should be determined by the protection scope of the claims.

Claims

A kind of Wei's method automatic erythrocyte sedimentation rate dynamic analyzer, is characterized in that, comprises:

A transmission device, the transmission device is used to place the blood sample to be tested, and the turntable of the transmission device is provided with several holes for placing the blood sample;

Sampling device, the sampling device is used to draw the blood sample into the Widman's ESR tube, and the blood sample enters the Wei's ESR tube through the injection needle, the valve group and the silicone tube connected to the Wei's ESR tube. In the erythrocyte sedimentation glass tube;

A detection device, the detection device is used to detect the liquid level of the blood sample in the Widman's erythrocyte sedimentation glass tube;

A cleaning device, the cleaning device is used for cleaning and drying the Wilcoxon ESR glass tube after the test.
The automatic erythrocyte sedimentation rate dynamic analyzer according to claim 1, wherein the sampling device includes a first moving mechanism, and the first moving mechanism drives the sampling needle to slide up and down , and the lower part of the support for fixing the first moving mechanism is provided with a needle washer, and the needle washer is used for cleaning the sampling needle.
The automatic erythrocyte sedimentation rate dynamic analyzer according to claim 1, wherein the detection device comprises a second moving mechanism and a detection plate, and the second moving mechanism drives the detection plate along the The axial direction of the Wilcox ESR glass tube moves linearly, and a sensor is arranged on the detection board, and the sensor is used to detect the height of the blood sample in the Wilcox ESR glass tube.
The automatic erythrocyte sedimentation rate dynamic analyzer according to claim 1, wherein the cleaning device includes a cleaning mechanism and a drying mechanism;

The cleaning mechanism includes a cleaning pump, a transition cylinder, and a cleaning solution bucket. One end of the cleaning pump communicates with the Widman's ESR tube, and the other end communicates with the liquid outlet of the transition cylinder. The liquid port communicates with the cleaning liquid barrel;

The drying mechanism includes an air blowing pump, one end of the air blowing pump is communicated with the Wilcox ESR tube, and the other end is communicated with the atmosphere.
The automatic erythrocyte sedimentation rate dynamic analyzer according to claim 4, wherein a heating element is arranged in the transition cylinder, and the heating element is used to heat the cleaning liquid in the transition cylinder to set temperature.
The automatic erythrocyte sedimentation rate dynamic analyzer according to claim 1, wherein the transmission device comprises a first drive mechanism and a turntable mechanism;

The turntable mechanism includes a first turntable and a second turntable, the first turntable is used to place blood sample test tubes, the second turntable is arranged below the first turntable, and the upper surface of the second turntable is in contact with the test tube Bottom abutment, used to accept test tubes;

The first driving mechanism drives the turntable mechanism to rotate so that the holes are located directly below the sample feeding device.
The automatic erythrocyte sedimentation rate dynamic analyzer according to claim 1, characterized in that, the dynamic analyzer also includes a waste liquid collection bucket, and the waste liquid collection bucket is arranged on one side of the dynamic analyzer. The side is used to store the waste liquid after cleaning the Widgers ESR glass tube and the blood sample after the test.
A kind of detection method of a kind of Wei's method automatic erythrocyte sedimentation dynamic analyzer as described in any one in claim 1-7, it is characterized in that, comprises the following steps:

Use the sampling needle to draw the blood sample into the Weisser's ESR tube;

Carrying out multiple detections to the liquid level height of the blood sample in the Weirdler's erythrocyte sedimentation glass tube;

The blood sample after the test is recovered, and the Wiltshire ESR glass tube is cleaned.
According to claim 8, the detection method of a kind of Wei's method full-automatic erythrocyte sedimentation analyzer, is characterized in that, said using the sampling needle to suck the blood sample into the Wei's erythrocyte sedimentation glass tube, before also comprising:

Place the blood sample test tubes in turn on the holes of the turntable according to the rules;

The transmission device is used to rotate the turntable to rotate the blood sample test tube directly under the sampling device.
According to claim 8, the detection method of a kind of Wei's method full-automatic erythrocyte sedimentation analyzer, is characterized in that, said using the sampling needle to suck the blood sample into the Wei's erythrocyte sedimentation glass tube, before also comprising:

Use the detection board to detect whether the blood sample has reached the set height in the Weisser's ESR tube.