CN205463469U - External immunological reagents's automatic cup wiper mechanism of sample - Google Patents

External immunological reagents's automatic cup wiper mechanism of sample Download PDF

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Publication number
CN205463469U
CN205463469U CN201620090858.6U CN201620090858U CN205463469U CN 205463469 U CN205463469 U CN 205463469U CN 201620090858 U CN201620090858 U CN 201620090858U CN 205463469 U CN205463469 U CN 205463469U
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liquid
plate
sample
needle
washing
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赵焕朝
郭凯
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HENAN MAINCARE BIOLOGICAL TECHNOLOGY Co Ltd
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HENAN MAINCARE BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

本实用新型涉及一种体外免疫试剂的样品自动清洗杯清洗机构,有效的解决了传统的清洗机构精确度低、需要手工拍干、操作麻烦的问题;其解决的技术方案是包括底板,底板上设有立柱支撑架,立柱支撑架之间设有洗液板,洗液板上设有通孔,通孔内穿过有洗液加液针,加液针内装有塑料管,加液针的上端连接有加液泵,通孔外周设有吸液针,吸液针的上端经硅胶管连接负压气源,底板上设有置于吸液针下方的样品杯架,样品杯架经置于底板上的导轨驱动,构成样品杯架可在底板上横向移动的结构,吸液针的正下方设有传感器,构成传感器可检测吸液针下方是否有样品杯架的结构;本实用新型保证检测结果的准确性。

The utility model relates to a sample automatic cleaning cup cleaning mechanism for in vitro immune reagents, which effectively solves the problems of low precision of the traditional cleaning mechanism, needing to be manually patted dry, and cumbersome operation; There is a column support frame, a washing liquid plate is arranged between the column support frames, and a through hole is arranged on the washing liquid plate, and a liquid adding needle passes through the through hole, and a plastic tube is installed in the liquid adding needle. The upper end is connected with a liquid pump, and a liquid-absorbing needle is arranged on the periphery of the through hole. The upper end of the liquid-absorbing needle is connected to a negative pressure air source through a silicone tube. Driven by the guide rail on the base plate, the sample cup holder can move laterally on the base plate, and a sensor is arranged directly under the liquid suction needle to form a structure where the sensor can detect whether there is a sample cup holder under the liquid suction needle; the utility model guarantees Accuracy of test results.

Description

一种体外免疫试剂的样品自动杯清洗机构 A sample automatic cup cleaning mechanism for in vitro immunological reagents

技术领域 technical field

本实用新型涉及体外诊断医疗器械技术领域,特别是一种体外免疫试剂的样品自动清洗杯清洗机构。 The utility model relates to the technical field of in vitro diagnostic medical devices, in particular to a sample automatic cleaning cup cleaning mechanism for in vitro immune reagents.

背景技术 Background technique

体外免疫试剂是通过免疫试剂在体外样品杯内发生免疫反应,检测患者血清或其他体液的一些物质含量,从而对人体进行免疫分析的医学检验试剂。将定量的患者血清或其他体液加入到固相包被有抗体的标准微孔板的反应杯中,血清中的待测分子与标记酶和固相载体上的抗体特异性结合,分离清洗掉未反应的游离成分;然后加入底物液,利用酶促化学反应产生的颜色或光子变化,通过机器判读,依次由光子计数器读出数值,并根据标准品建立的数学模型进行定量分析,便能得出检测分析结果。 In vitro immunological reagents are medical testing reagents for immune analysis of the human body by detecting the content of some substances in the patient's serum or other body fluids through the immune reaction of the immune reagents in the in vitro sample cup. Add quantitative patient serum or other body fluids to the cuvette of a standard microwell plate coated with antibodies on the solid phase. The free components of the reaction; then add the substrate solution, use the color or photon changes produced by the enzymatic chemical reaction, through machine interpretation, read the values by the photon counter in turn, and perform quantitative analysis according to the mathematical model established by the standard, you can get Get the analysis results.

清洗的精确与否和清洗后残留物直接影响检测结果,传统洗板机通过分配管对一排管道分配液体,受管道长度和维护效果影响,不同反应杯的清洗效果不同,导致反应杯间差异较大。 The accuracy of cleaning and the residue after cleaning directly affect the test results. The traditional plate washer distributes the liquid to a row of pipelines through the distribution pipe. Affected by the length of the pipeline and the maintenance effect, the cleaning effect of different cuvettes is different, resulting in differences between cuvettes larger.

传统洗板机采用单针吸液,液体残留大,需要手工将反应杯在吸水纸上拍干,操作麻烦,精确度不够。 The traditional plate washer uses a single needle to absorb liquid, and the liquid residue is large. It is necessary to manually pat the cuvette dry on absorbent paper, which is troublesome to operate and not accurate enough.

所以有必要找到一种方式来解决此问题。 So it is necessary to find a way to solve this problem.

发明内容 Contents of the invention

针对上述情况,为克服现有技术之缺陷,本实用新型之目的就是提供一种体外免疫试剂的样品自动清洗杯清洗机构,有效的解决了传统的清洗机构精确度低、需要手工拍干、操作麻烦的问题。 In view of the above situation, in order to overcome the defects of the prior art, the purpose of this utility model is to provide a sample automatic cleaning cup cleaning mechanism for in vitro immunological reagents, which effectively solves the problem of low precision of the traditional cleaning mechanism and the need for manual drying and operation. Troublesome question.

其解决的技术方案是,包括底板,底板上设有竖向的多根立柱支撑架,多根立柱支撑架之间设有横向放置的且可升降的洗液板,洗液板上设有通孔,通孔内穿过有上端固定的竖向洗液加液针,加液针内装有塑料管,加液针的上端连接有加液泵,通孔外周设有穿过洗液板且固定在洗液板上的三根呈“品”字状的吸液针,吸液针的上端经硅胶管连接负压气源,底板上设有置于吸液针下方的样品杯架,样品杯架经置于底板上的导轨驱动,构成样品杯架可在底板上横向移动的结构,吸液针的正下方设有传感器,构成传感器可检测吸液针下方是否有样品杯架的结构。 The technical solution is to include a bottom plate, a plurality of vertical column support frames are arranged on the bottom plate, a horizontally placed and liftable washing liquid plate is arranged between the multiple vertical column support frames, and a liquid washing plate is provided on the liquid washing plate. There is a vertical lotion filling needle with a fixed upper end passing through the through hole. A plastic tube is installed inside the liquid filling needle. The upper end of the liquid filling needle is connected to a liquid filling pump. There are three liquid-absorbing needles in the shape of "product" on the washing liquid plate. The upper end of the liquid-absorbing needle is connected to a negative pressure air source through a silicone tube. There is a sample cup holder placed under the liquid-absorbing needle on the bottom plate. Driven by the guide rail placed on the bottom plate, the structure of the sample cup holder can move laterally on the bottom plate. A sensor is installed directly under the liquid aspiration needle to form a structure that the sensor can detect whether there is a sample cup holder under the liquid aspiration needle.

本实用新型结构巧妙,采用以上技术方案的体外免疫试剂样品杯的自动清洗机构,通过一个清洗单元对每个反应杯进行清洗,使每个反应杯的洗涤效果一致,从而减少清洗变异,保证检测结果的准确性;同时采用品字形三针吸取废液,液体残留小,无需手工拍干,加快了清洗速度,提高了仪器的效率,支撑结构和工作结构合成一体,机器紧凑,占用空间小,使检测仪器便于小型化和自动化。 The utility model has an ingenious structure, adopts the automatic cleaning mechanism of the in vitro immune reagent sample cup of the above technical scheme, and cleans each reaction cup through a cleaning unit, so that the washing effect of each reaction cup is consistent, thereby reducing cleaning variation and ensuring detection The accuracy of the results; at the same time, the three needles in the shape of a square are used to absorb the waste liquid, the liquid remains small, and there is no need to manually pat dry, which speeds up the cleaning speed and improves the efficiency of the instrument. The support structure and the working structure are integrated, the machine is compact, and the space is small The detection instrument is convenient for miniaturization and automation.

附图说明 Description of drawings

图1为本实用新型结构示意图。 Fig. 1 is the structural representation of the utility model.

图2为本实用新型主视图示意图。 Fig. 2 is a schematic diagram of the front view of the utility model.

具体实施方式 detailed description

以下结合附图对本实用新型的具体实施方式作进一步详细说明。 The specific embodiments of the present utility model will be described in further detail below in conjunction with the accompanying drawings.

由图1至图2给出,本实用新型包括底板1,底板1上设有竖向的多根立柱支撑架2,多根立柱支撑架2之间设有横向放置的且可升降的洗液板3,洗液板3上设有通孔4,通孔4内穿过有上端固定的竖向洗液加液针5,加液针5内装有塑料管6,加液针5的上端连接有加液泵7,通孔4外周设有穿过洗液板3且固定在洗液板3上的三根呈“品”字状的吸液针8,吸液针8的上端经硅胶管9连接负压气源10,底板1上设有置于吸液针8下方的样品杯架11,样品杯架11经置于底板1上的导轨驱动,构成样品杯架11可在底板1上横向移动的结构,吸液针8的正下方设有传感器12,构成传感器12可检测吸液针8下方是否有样品杯架11的结构。 Given by Fig. 1 to Fig. 2, the utility model comprises a base plate 1, on which a plurality of vertical column support frames 2 are arranged, and a horizontally placed and liftable washing liquid is arranged between the plurality of column support frames 2 Plate 3, liquid washing plate 3 is provided with a through hole 4, through the through hole 4 there is a vertical lotion liquid feeding needle 5 with a fixed upper end, and a plastic tube 6 is housed in the liquid adding needle 5, and the upper end of the liquid adding needle 5 is connected to There is a liquid filling pump 7, and the outer periphery of the through hole 4 is provided with three liquid-absorbing needles 8 in the shape of "product" that pass through the lotion plate 3 and are fixed on the lotion plate 3. The upper ends of the liquid-absorbing needles 8 pass through the silicone tube 9 Connect the negative pressure air source 10, the bottom plate 1 is provided with a sample cup holder 11 placed under the liquid suction needle 8, the sample cup holder 11 is driven by the guide rail placed on the bottom plate 1, and the sample cup holder 11 can be horizontally placed on the bottom plate 1 In the moving structure, a sensor 12 is provided directly under the liquid aspirating needle 8 , so that the sensor 12 can detect whether there is a sample cup holder 11 under the liquid aspirating needle 8 .

所述的立柱支撑架2有四根,洗液板3为矩形,洗液板3的四角套在立柱支撑架2上。 There are four column support frames 2, and the washing liquid plate 3 is rectangular, and the four corners of the liquid washing plate 3 are sleeved on the column support frame 2.

所述的洗液板3经置于其下端的升降电机13驱动,构成洗液板3可在立柱支撑架2上上下移动的结构。 The liquid washing plate 3 is driven by the lifting motor 13 placed at its lower end, forming a structure in which the liquid washing plate 3 can move up and down on the column support frame 2 .

所述的立柱支撑架2上设有连接洗液板3的复位弹簧14,构成洗液板3向下运动完毕后可自动复位的结构。 The support frame 2 of the column is provided with a return spring 14 connected to the washing liquid plate 3 to form a structure that the liquid washing plate 3 can automatically reset after the downward movement is completed.

所述的通孔4置于洗液板3的中间位置。 The through hole 4 is placed in the middle of the washing liquid plate 3 .

所述的洗液加液针5为中空不锈钢管。 The lotion adding needle 5 is a hollow stainless steel tube.

所述的导轨包括置于底板1上的横向定位导轨15,定位导轨15为凹槽状,定位导轨15内边设有精密螺纹16,样品杯架11连接有可在定位导轨15内移动且与精密螺纹16配合的电机17,构成电机17驱动样品杯架11在定位导轨15上横向移动的结构。 The guide rail includes a horizontal positioning guide rail 15 placed on the base plate 1, the positioning guide rail 15 is groove-shaped, and the inner edge of the positioning guide rail 15 is provided with a precision thread 16, and the sample cup holder 11 is connected with a The motor 17 matched with the precision thread 16 constitutes a structure in which the motor 17 drives the sample cup holder 11 to move laterally on the positioning guide rail 15 .

所述的传感器12为光电耦合器。 The sensor 12 is a photocoupler.

本实用新型使用时, When the utility model is used,

把反应杯放入样品杯架11内,电机17驱动样品杯架11在定位导轨15内与精密螺纹16配合,使反应杯横向移动至吸液针8的正下方,此时光电耦合器接受信号使反应杯停止运动,加液泵7将洗液通过加液针5内的塑料管添加到反应杯内。 Put the reaction cup into the sample cup holder 11, the motor 17 drives the sample cup holder 11 to cooperate with the precision thread 16 in the positioning guide rail 15, so that the reaction cup moves laterally to the directly below the liquid suction needle 8, at this time the photoelectric coupler receives the signal The reaction cup is stopped, and the liquid addition pump 7 adds the washing solution into the reaction cup through the plastic tube in the liquid addition needle 5 .

升降电机13驱动洗液板3向下运动,洗液板3带动吸液针8向下运动,吸液针8将反应杯内的液体经负压气源10抽走,工作完毕之后,复位弹簧14将洗液板3拉回原处。 The lifting motor 13 drives the liquid washing plate 3 to move downward, and the liquid washing plate 3 drives the liquid suction needle 8 to move downward. The liquid suction needle 8 sucks the liquid in the cuvette away through the negative pressure air source 10. After the work is completed, the return spring 14Pull the wash plate 3 back to its original position.

本实用新型利用单一洗液加注和清洗机构,清洗过程相同,降低了洗涤变异,保证结果准确。 The utility model utilizes a single lotion filling and cleaning mechanism, the cleaning process is the same, the washing variation is reduced, and the result is guaranteed to be accurate.

本实用新型采用“品”字形三针吸取废液,吸取速度快,加快了清洗速度,提高了仪器的效率;传统洗板机采用单针吸液,液体残留大,需要手工将反应杯在吸水纸上拍干,而三针吸液,反应杯无死角,洗液残留极低,无需手工拍干反应杯。 The utility model adopts three needles in the shape of "product" to absorb waste liquid, and the absorption speed is fast, which speeds up the cleaning speed and improves the efficiency of the instrument; the traditional plate washing machine adopts a single needle to absorb liquid, and the liquid residue is large, and the reaction cup needs to be manually placed in the water absorption process. Pat dry on paper, and three-needle aspiration, the reaction cup has no dead angle, and the residue of washing liquid is extremely low, so there is no need to manually pat the reaction cup dry.

加液针5采用固定式,降低了压力部件的故障率,加液更均匀;吸液针8是洗液加注固定管,洗液通过钢针内部的塑料管6加入反应杯,易于调节加液针5的高度,如果发生加液针堵塞,只需将塑料管6抽出更换即可,无需人员在狭小机器内部用通针疏通,易于维护。 The liquid filling needle 5 is fixed, which reduces the failure rate of the pressure parts, and the liquid filling is more uniform; the liquid suction needle 8 is a fixed tube for lotion filling, and the lotion is added to the cuvette through the plastic tube 6 inside the steel needle, which is easy to adjust and add. The height of the liquid needle 5, if the liquid-feeding needle is blocked, it is only necessary to extract the plastic tube 6 to replace it, and it is not necessary for personnel to dredge it with a through needle inside the narrow and small machine, which is easy to maintain.

洗液板3采用升降电机13和复位弹簧14控制,减少了使用丝杆电机导轨驱动的复杂性,弹簧复位快速、稳定,维护简单,降低了产品的造价和维护成本。 The liquid washing plate 3 is controlled by a lifting motor 13 and a return spring 14, which reduces the complexity of using a screw motor guide rail drive, and the spring reset is fast and stable, and the maintenance is simple, which reduces the cost of the product and the maintenance cost.

水平导轨,采用光电耦合器,反应杯在导轨滑块移动到吸液针正下方时,传感器正好落在导轨的通孔处,光电耦合器得到光电感应,加液针和吸液针开始工作,避免了吸液针误操作,液体漏入机器,损坏电子元件。 The horizontal guide rail adopts a photoelectric coupler. When the cuvette moves directly below the liquid aspiration needle, the sensor just falls on the through hole of the guide rail. It avoids the misoperation of the liquid suction needle, the liquid leaks into the machine, and damages the electronic components.

本实用新型结构巧妙,采用以上技术方案的体外免疫试剂样品杯的自动清洗机构,通过一个清洗单元对每个反应杯进行清洗,使每个反应杯的洗涤效果一致,从而减少清洗变异,保证检测结果的准确性;同时采用品字形三针吸取废液,液体残留小,无需手工拍干,加快了清洗速度,提高了仪器的效率,支撑结构和工作结构合成一体,机器紧凑,占用空间小,使检测仪器便于小型化和自动化。 The utility model has an ingenious structure, adopts the automatic cleaning mechanism of the in vitro immune reagent sample cup of the above technical scheme, and cleans each reaction cup through a cleaning unit, so that the washing effect of each reaction cup is consistent, thereby reducing cleaning variation and ensuring detection The accuracy of the results; at the same time, the three needles in the shape of a square are used to absorb the waste liquid, the liquid remains small, and there is no need to manually pat dry, which speeds up the cleaning speed and improves the efficiency of the instrument. The support structure and the working structure are integrated, the machine is compact, and the space is small The detection instrument is convenient for miniaturization and automation.

Claims (8)

1.一种体外免疫试剂的样品自动清洗杯清洗机构,包括底板(1),其特征在于,底板(1)上设有竖向的多根立柱支撑架(2),多根立柱支撑架(2)之间设有横向放置的且可升降的洗液板(3),洗液板(3)上设有通孔(4),通孔(4)内穿过有上端固定的竖向洗液加液针(5),加液针(5)内装有塑料管(6),加液针(5)的上端连接有加液泵(7)上,通孔(4)外周设有穿过洗液板(3)且固定在洗液板(3)上的三根呈“品”字状的吸液针(8),吸液针(8)的上端经硅胶管(9)连接负压气源(10),底板(1)上设有置于吸液针(8)下方的样品杯架(11),样品杯架(11)经置于底板(1)上的导轨驱动,构成样品杯架(11)可在底板(1)上横向移动的结构,吸液针(8)的正下方设有传感器(12),构成传感器(12)可检测吸液针(8)下方是否有样品杯架(11)的结构。 1. A sample automatic cleaning cup cleaning mechanism for in vitro immunological reagents, comprising a base plate (1), characterized in that the base plate (1) is provided with a plurality of vertical column support frames (2), and a plurality of column support frames ( 2) There is a horizontally placed and liftable washing plate (3), and a through hole (4) is provided on the washing plate (3), and a vertical washing plate with a fixed upper end passes through the through hole (4). Liquid-filling needle (5), the plastic tube (6) is installed inside the liquid-filling needle (5), the upper end of the liquid-filling needle (5) is connected to the liquid-filling pump (7), and the outer periphery of the through hole (4) is provided with a Washing plate (3) and three liquid-absorbing needles (8) in the shape of "product" fixed on the washing plate (3), the upper end of the liquid-absorbing needle (8) is connected to negative pressure gas The source (10), the bottom plate (1) is provided with a sample cup holder (11) placed under the liquid aspiration needle (8), and the sample cup holder (11) is driven by a guide rail placed on the bottom plate (1) to form a sample cup The frame (11) can move laterally on the bottom plate (1), and the sensor (12) is arranged directly under the liquid aspiration needle (8), and the sensor (12) can detect whether there is a sample cup under the liquid aspiration needle (8) The structure of frame (11). 2.根据权利要求1所述的一种体外免疫试剂的样品自动清洗杯清洗机构,其特征在于,所述的立柱支撑架(2)有四根,洗液板(3)为矩形,洗液板(3)的四角套在立柱支撑架(2)上。 2. The sample automatic cleaning cup cleaning mechanism for in vitro immunological reagents according to claim 1, characterized in that, there are four column support frames (2), the washing liquid plate (3) is rectangular, and the washing liquid The four corners of the plate (3) are sleeved on the column support frame (2). 3.根据权利要求1所述的一种体外免疫试剂的样品自动清洗杯清洗机构,其特征在于,所述的洗液板(3)经置于其下端的升降电机(13)驱动,构成洗液板(3)可在立柱支撑架(2)上上下移动的结构。 3. The cleaning mechanism of an automatic sample cleaning cup for in vitro immunological reagents according to claim 1, characterized in that the washing liquid plate (3) is driven by a lifting motor (13) placed at its lower end to form a washing machine. The liquid plate (3) can move up and down on the column support frame (2). 4.根据权利要求3所述的一种体外免疫试剂的样品自动清洗杯清洗机构,其特征在于,所述的立柱支撑架(2)上设有连接洗液板(3)的复位弹簧(14),构成洗液板(3)向下运动完毕后可自动复位的结构。 4. The sample automatic cleaning cup cleaning mechanism for in vitro immunological reagents according to claim 3, characterized in that, the column support frame (2) is provided with a return spring (14) connected to the washing liquid plate (3) ), constituting the structure that the washing liquid plate (3) can be automatically reset after the downward movement is completed. 5.根据权利要求1所述的一种体外免疫试剂的样品自动清洗杯清洗机构,其特征在于,所述的通孔(4)置于洗液板(3)的中间位置。 5 . The cleaning mechanism of an automatic sample cleaning cup for in vitro immunological reagents according to claim 1 , wherein the through hole ( 4 ) is placed in the middle of the washing liquid plate ( 3 ). 6.根据权利要求1所述的一种体外免疫试剂的样品自动清洗杯清洗机构,其特征在于,所述的洗液加液针(5)为中空不锈钢管。 6 . The cleaning mechanism of an automatic sample cleaning cup for in vitro immunological reagents according to claim 1 , characterized in that the lotion adding needle ( 5 ) is a hollow stainless steel tube. 7.根据权利要求1所述的一种体外免疫试剂的样品自动清洗杯清洗机构,其特征在于,所述的导轨包括置于底板(1)上的横向定位导轨(15),定位导轨(15)为凹槽状,定位导轨(15)内边设有精密螺纹(16),样品杯架(11)连接有可在定位导轨(15)内移动且与精密螺纹(16)配合的电机(17),构成电机(17)驱动样品杯架(11)在定位导轨(15)上横向移动的结构。 7. A sample automatic cleaning cup cleaning mechanism for in vitro immunological reagents according to claim 1, characterized in that, the guide rails include horizontal positioning guide rails (15) placed on the bottom plate (1), and the positioning guide rails (15 ) is groove-shaped, and the inner side of the positioning guide rail (15) is provided with a precision thread (16), and the sample cup holder (11) is connected with a motor (17) that can move in the positioning guide rail (15) and cooperate with the precision thread (16) ), forming a structure in which the motor (17) drives the sample cup holder (11) to move laterally on the positioning guide rail (15). 8.根据权利要求1所述的一种体外免疫试剂的样品自动清洗杯清洗机构,其特征在于,所述的传感器(12)为光电耦合器。 8 . The automatic sample cleaning mechanism for in vitro immunological reagents according to claim 1 , wherein the sensor ( 12 ) is a photocoupler.
CN201620090858.6U 2016-01-29 2016-01-29 External immunological reagents's automatic cup wiper mechanism of sample Expired - Fee Related CN205463469U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106694490A (en) * 2016-12-09 2017-05-24 中储粮成都粮食储藏科学研究所 Utensil washing device
CN107525767A (en) * 2017-09-21 2017-12-29 丽水市创峰科技有限公司 Dietetic food detection device
CN112722589A (en) * 2020-12-23 2021-04-30 贵州金域医学检验中心有限公司 Respiratory tract virus detection kit prepared based on antibacterial material and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106694490A (en) * 2016-12-09 2017-05-24 中储粮成都粮食储藏科学研究所 Utensil washing device
CN107525767A (en) * 2017-09-21 2017-12-29 丽水市创峰科技有限公司 Dietetic food detection device
CN107525767B (en) * 2017-09-21 2024-01-19 丽水市创峰科技有限公司 Medical food testing equipment
CN112722589A (en) * 2020-12-23 2021-04-30 贵州金域医学检验中心有限公司 Respiratory tract virus detection kit prepared based on antibacterial material and preparation method thereof

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