WO2021109509A1 - Composition ayant une fonction d'amélioration de l'immunité et son procédé de préparation - Google Patents

Composition ayant une fonction d'amélioration de l'immunité et son procédé de préparation Download PDF

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Publication number
WO2021109509A1
WO2021109509A1 PCT/CN2020/094722 CN2020094722W WO2021109509A1 WO 2021109509 A1 WO2021109509 A1 WO 2021109509A1 CN 2020094722 W CN2020094722 W CN 2020094722W WO 2021109509 A1 WO2021109509 A1 WO 2021109509A1
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Prior art keywords
parts
ginseng
licorice
refrigerator
add
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PCT/CN2020/094722
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English (en)
Chinese (zh)
Inventor
肖伟
范业文
刘世娟
王振东
张海弢
李曼曼
柏伟荣
Original Assignee
江苏康仁医药科技开发有限公司
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Publication of WO2021109509A1 publication Critical patent/WO2021109509A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • the invention relates to the technical fields of medicines, health products and foods, and in particular to a composition with the function of improving immunity and a preparation method thereof.
  • the invention intends to provide a Chinese herbal medicine composition, a drink and a preparation method thereof, which are aimed at sub-healthy people with low immunity, have a refreshing and pleasant mouthfeel, suitable for all seasons, and have a better immunity-improving effect.
  • the present invention proposes a composition with a function of improving immunity, comprising by weight: 1-12 parts of Poria cocos, 0.1-6 parts of wolfberry, 0.1-6 parts of Coix seed, 0.1-4 parts of ginseng, and 0.1-4 parts of licorice Copies.
  • the composition and the raw materials used can be directly ground into powder, or it can be an extract prepared by conventional means or other forms.
  • composition includes: 2-10 parts of Poria cocos, 0.5-6 parts of wolfberry, 0.5-6 parts of Coix seed, 0.2-3 parts of ginseng, and 0.2-3 parts of licorice.
  • composition includes: 3-8 parts of Poria cocos, 1-5 parts of Lycium barbarum, 1-5 parts of Coix seed, 0.5-2.5 parts of ginseng, and 0.5-2.5 parts of licorice.
  • composition includes: 4-8 parts of Poria cocos, 1-3 parts of wolfberry, 1-3 parts of coix seed, 0.5-2 parts of ginseng, and 0.5-2 parts of licorice.
  • composition includes: 8 parts of Poria cocos, 1 part of Chinese wolfberry, 1 part of Coix seed, 1 part of ginseng, and 1 part of licorice.
  • the present invention also proposes the application of any of the preceding compositions in the preparation of immunity-enhancing drugs, health products or foods.
  • the present invention also proposes a medicine, health care product or food with a composition capable of improving immunity as any of the previous items, which may include acceptable excipients in the medicine, health care product or food,
  • the health food or food may be selected from beverages.
  • the beverage also includes one or more of white sugar, xylitol, sorbitol, and erythritol.
  • sorbitol and citric acid Preferable are sorbitol and citric acid, and the ratio of sugar to acid is preferably 156:11-12.
  • the present invention also provides a method for preparing a health product or food as described above, and the preparation method includes the following steps:
  • the preparation method includes the following steps:
  • Blending In the purification workshop, take the clarified concentrate in (2), add purified water to dilute and mix, the ratio of the clarified concentrate to purified water is 1:1 ⁇ 1:8, and then add the corrective ( Including sweeteners and acidity regulators), dissolve, mix, and stand in a refrigerator at 4°C for 12 to 72 hours.
  • corrective Including sweeteners and acidity regulators
  • the preparation method includes the following steps:
  • Packaging sub-packaging and packaging.
  • Poria, Lycium barbarum, Coix seed and licorice are all of the same medicine and food, and ginseng (artificially planted) is a new food raw material, which can be used for ordinary foods, which not only has food safety but also enhances the body's immunity.
  • the beverage made by the composition of the present invention has a refreshing and pleasant taste, is suitable for all seasons, and is convenient for consumers to accept.
  • Poria cocos has a sweet and flat taste, enters the heart, lungs, and spleen channels, and can be used for edema, oliguria, phlegm, palpitations, spleen deficiency, low food, loose stools, diarrhea, restlessness, palpitations, and insomnia; medlar nourishes the kidney, nourishes the liver, Improve eyesight, strengthen muscles and bones, and relieve fatigue; Coix seed can be used for edema, athlete's foot, dysuria, diarrhea of spleen deficiency, etc.; Ginseng is returned to the spleen, lung meridian, and heart meridian, which can greatly invigorate vitality; the five drugs are used in combination, complementing each other, and the obtained solid The pharmacodynamic experiment of the drink has proved that it can significantly improve the phagocytic ability of mononuclear-macrophages in mice, enhance the transformation ability of mouse spleen lymphocytes,
  • a drink for improving immunity weighing raw materials according to the following weight ratio: Poria 60kg, Lycium chinense 20kg, Coix seed 20kg, Ginseng (artificially planted) 10kg, Licorice 10kg, Sorbitol 93.15kg, Citric acid 0.69kg.
  • the specific preparation method is as follows:
  • Sub-packaging and packaging are carried out in the outer packaging workshop, that is, to improve the immunity of the drink.
  • a drink for improving immunity weighing raw materials according to the following weight ratio: Poria cocos 80 kg, wolfberry 15 kg, coix seed 15 kg, ginseng (artificial planting) 5 kg, licorice 5 kg, erythritol 93.15 kg, and citric acid 0.69 kg.
  • the specific preparation method is as follows:
  • Blending In the purification workshop, take the clarified concentrate from (2), add purified water, the ratio of the clarified concentrate to purified water is 1:4, mix well, then add erythritol and citric acid to blend, Dissolve, mix, and let stand in a refrigerator at 4°C for 48h.
  • Sub-packaging and packaging are carried out in the outer packaging workshop, that is, to improve the immunity of the drink.
  • a drink for improving immunity weighing raw materials according to the following weight ratio: Poria cocos 40 kg, wolfberry 30 kg, coix seed 30 kg, ginseng (artificially planted) 10 kg, licorice 10 kg, sorbitol 93.15 kg, and citric acid 0.39 kg.
  • the specific preparation method is as follows:
  • Sub-packaging and packaging are carried out in the outer packaging workshop, that is, to improve the immunity of the drink.
  • a drink for improving immunity weighing raw materials according to the following weight ratio: Poria cocos 80kg, wolfberry 10kg, coix seed 10kg, ginseng (artificially planted) 10kg, licorice 10kg, xylitol 93.15kg, and citric acid 0.69kg.
  • the specific preparation method is as follows:
  • Sub-packaging and packaging are carried out in the outer packaging workshop, that is, to improve the immunity of the drink.
  • a drink for improving immunity The raw materials are weighed according to the following weight ratio: Poria 60kg, Lycium barbarum 15kg, Coix seed 15kg, Ginseng (artificially planted) 15kg, Licorice 15kg, White sugar 93.15kg, and citric acid 0.69kg.
  • the specific preparation method is as follows:
  • Sub-packaging and packaging are carried out in the outer packaging workshop, that is, to improve the immunity of the drink.
  • ICR mouse clean grade, 18-22g, male.
  • immune group I and immunization group II were set up, and the blank group, the control group (0.16g/kg ⁇ BW, equivalent to 5 times the recommended amount of human body,), the experimental group (given the clarified concentrate prepared in Example 1 1.15 g/kg ⁇ BW (equivalent to 1g crude drug/kg ⁇ BW, 5 times the recommended amount of the human body), 10 per group; immune group I was used for the mouse lymphocyte transformation experiment, and immune group II was used for the carbon clearance experiment.
  • the group and the experimental group were given intragastric administration at 1.0mL/kg ⁇ bw, and the blank group was given an equal volume of purified water once a day. After continuous administration for 30 days, various indexes were measured.
  • Positive control drug Dendrobium candidum and American ginseng capsules (recommended dose 1.92g/d for human body).
  • Experimental group drug the clarified concentrated liquid in Example 1 (the weight ratio of the medicinal materials to the clarified concentrated liquid is 1: 1.15).
  • a cell suspension Take the spleen aseptically to prepare a cell suspension, adjust the cell concentration to 3 ⁇ 10 6 cells/mL.
  • the cell suspension was added to a 24-well culture plate in two wells, 1 mL per well, 75 ⁇ L of ConA solution was added to one hole, and the other hole was used as a control, and cultured in a 5% CO 2 , 37° C. incubator for 72 hours.
  • Remove 0.7mL of the supernatant add 0.7mL of RPMI1640 culture medium without calf serum, add 50 ⁇ L/well of MTT, continue to incubate for 4h, add 1mL of acidic isopropanol, and dissolve it into a 96-well culture plate.
  • mice were injected with Indian ink diluted 4 times with normal saline into the tail vein, and timed immediately after ink was injected. At 2 and 10 minutes after the ink was injected, 20 ⁇ L of blood was taken from the medial canthal vein and added to 2 mL of 0.1% Na 2 CO 3 solution, and the optical density (OD) was measured at a wavelength of 600 nm. The mice were sacrificed, the liver and spleen were weighed, and the phagocytic index was calculated.
  • Phagocytosis index a end weight ⁇ K 1/3 (liver weight + spleen weight)
  • the present invention can significantly improve the phagocytic ability of mononuclear-macrophages in mice, and can enhance the transformation ability of mouse spleen lymphocytes, indicating that the present invention has the function of enhancing immunity.
  • the drink of the present invention have a suitable taste, it is necessary to add a certain amount of sweetener, and the formation of the flavor of the drink is produced by the combination of the sweetener and the Chinese medicinal material extract, and the appropriate sweetness can cover the bitter taste of the Chinese medicinal material , Make the taste more pleasant.
  • Example 1 Take the clarified concentrated liquid in Example 1, 100g each, 6 parts in total, according to the ratio of clarified concentrated liquid to purified water of 1:1, 1:2, 1:3, 1:4, 1:5 and 1:6 Dilute, mix well, and perform sensory evaluation.
  • the experimental results show that when the ratio of clarified concentrated liquid to purified water is 1:4, the sensory score is the highest, the characteristic flavor is appropriate, and will not be too thick or too weak; when the ratio of clarified concentrated liquid to purified water is 1:1 to 3, the characteristic flavor Too strong, the bitterness is strong; when the ratio of clarified concentrate to purified water is 1:5-6, the characteristic flavor is too weak, and the taste is weak. Therefore, the ratio of clarified concentrate to purified water is 1:4.
  • Example 1 Take the clarified concentrated solution in Example 1 and dilute it according to the ratio of clarified concentrated solution to purified water of 1:4. Take 4 portions, each 100g, and add 15.6g white sugar, xylitol, sorbitol, and erythritol. The sugar alcohol is stirred until it is completely dissolved, and the sensory evaluation is performed.
  • sorbitol has the highest sensory evaluation score and the most pleasant taste.
  • the sensory scores of drinks added with white sugar and xylitol are the lowest, because their sweetness is too high and the sweetness is too strong; the sensory scores of erythritol and sorbitol are similar, but the price of erythritol is higher, which is to control the cost Therefore, sorbitol was chosen as a sweetener.
  • Example 1 Take the clarified concentrated solution in Example 1 and dilute it according to the ratio of clarified concentrated solution to purified water of 1:4, take 5 portions, each 1000g, first add 156g sorbitol and stir until it is completely dissolved, then add 10.0g respectively , 11.0g, 11.5g, 12.0g, 13.0g, stir until completely dissolved, and perform sensory evaluation.
  • the preferred sweetener is sorbitol, and the preferred sugar-to-acid ratio is 156:11-12.

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

L'invention concerne une composition ayant une fonction d'amélioration de l'immunité, comprenant, en parties en poids : 1-12 parties de poria, 0,1-6 parties de Lycium chinense, 0,1-6 parties de graine de coicis, 0,1-4 parties de ginseng et 0,1-4 parties de Glycyrrhiza uralensis. L'utilisation combinée des cinq médicaments peut favoriser l'immunité cellulaire et la phagocytose chez des souris, et a un effet significatif d'amélioration de l'immunité.
PCT/CN2020/094722 2019-12-02 2020-06-05 Composition ayant une fonction d'amélioration de l'immunité et son procédé de préparation WO2021109509A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201911216167.0A CN110893222A (zh) 2019-12-02 2019-12-02 一种具有提高免疫力功能的组合物及其制备方法
CN201911216167.0 2019-12-02

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CN110893222A (zh) * 2019-12-02 2020-03-20 江苏康缘药业股份有限公司 一种具有提高免疫力功能的组合物及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101849596A (zh) * 2010-02-26 2010-10-06 湖北中烟工业有限责任公司 一种滋养补气保健茶及制作方法
CN105055497A (zh) * 2015-07-29 2015-11-18 湖北医药学院 一种四君子汤茶饮及其制备工艺
CN106729136A (zh) * 2016-11-28 2017-05-31 武汉哈福科技有限公司 一种调节免疫力的功能性食品
CN110893222A (zh) * 2019-12-02 2020-03-20 江苏康缘药业股份有限公司 一种具有提高免疫力功能的组合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985985A (zh) * 2006-12-13 2007-06-27 徐建阳 健脾扶正排毒养生食疗剂方及其制备方法、以及一种功能性食品
CN100534474C (zh) * 2006-12-19 2009-09-02 湖南补天药业有限公司 一种具有增强免疫功效的组合物及其制备方法和其用途
CN101524493B (zh) * 2009-03-24 2012-01-18 范永昌 一种多功能中药蜜丸
CN108713746A (zh) * 2018-05-31 2018-10-30 南京中生生物科技有限公司 一种药食同源组合物及其制备方法和应用
CN109007514A (zh) * 2018-08-10 2018-12-18 江苏康缘药业股份有限公司 一种具有提高免疫力功能的组合物及其制备方法
CN109077321A (zh) * 2018-10-29 2018-12-25 吕彦辉 一种具有增强免疫力和抗氧化作用的组合物及其制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101849596A (zh) * 2010-02-26 2010-10-06 湖北中烟工业有限责任公司 一种滋养补气保健茶及制作方法
CN105055497A (zh) * 2015-07-29 2015-11-18 湖北医药学院 一种四君子汤茶饮及其制备工艺
CN106729136A (zh) * 2016-11-28 2017-05-31 武汉哈福科技有限公司 一种调节免疫力的功能性食品
CN110893222A (zh) * 2019-12-02 2020-03-20 江苏康缘药业股份有限公司 一种具有提高免疫力功能的组合物及其制备方法

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