WO2020149067A1 - スタティックミキサー - Google Patents

スタティックミキサー Download PDF

Info

Publication number
WO2020149067A1
WO2020149067A1 PCT/JP2019/048793 JP2019048793W WO2020149067A1 WO 2020149067 A1 WO2020149067 A1 WO 2020149067A1 JP 2019048793 W JP2019048793 W JP 2019048793W WO 2020149067 A1 WO2020149067 A1 WO 2020149067A1
Authority
WO
WIPO (PCT)
Prior art keywords
liquid
mixer
turbulent diffusion
turbulent
static mixer
Prior art date
Application number
PCT/JP2019/048793
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
坊之下雅夫
矢野弘樹
飯島里枝
磯谷篤志
亀澤一寿
吉田健吾
茂木智博
桑嶋幹
Original Assignee
日本分光株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日本分光株式会社 filed Critical 日本分光株式会社
Priority to JP2020566154A priority Critical patent/JP7343191B2/ja
Priority to EP19910459.7A priority patent/EP3912710A4/en
Publication of WO2020149067A1 publication Critical patent/WO2020149067A1/ja

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/45—Mixing liquids with liquids; Emulsifying using flow mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
    • B01F25/43195—Wires or coils
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4338—Mixers with a succession of converging-diverging cross-sections, i.e. undulating cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4522—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through porous bodies, e.g. flat plates, blocks or cylinders, which obstruct the whole diameter of the tube
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/82—Combinations of dissimilar mixers
    • B01F33/821—Combinations of dissimilar mixers with consecutive receptacles

Definitions

  • the present invention relates to improvement of mixing efficiency in a mixer for mixing liquids, particularly in a static mixer for mixing two or more kinds of liquids.
  • static mixers have been used to mix liquids in various analytical fields such as liquid chromatography.
  • various types of static mixers and various innovations have been made according to their use.
  • various kinds of liquids and the like to be mixed and various devises have been made in order to be able to cope with these liquids and the like as a mixer and to increase the mixing efficiency.
  • Patent Document 1 a cross section of a cylindrical internal space of a pipe is divided into two, and a twisting blade element is arranged so as to form two flow paths, and the two twisting blade elements are formed.
  • a fluid agitator static mixer
  • Patent Document 2 a plurality of valves (ball valves or butterfly valves) are arranged in series in a half-open state inside a pipe, and adjacent valves are set to have different phases around the valve axis.
  • a technique relating to a fluid mixing apparatus capable of promoting turbulent flow of a liquid or the like that has passed therethrough and realizing sufficient mixing.
  • the stirring action can be improved by adding a simple device to the structure of the conventional static mixer in which a hole is provided at a predetermined position of the twisting blade element. Since the mixing is performed by the conventional mechanism, it cannot be said that the mixing efficiency is significantly improved.
  • Patent Document 2 by arranging a plurality of valves in series, turbulence can be promoted and sufficient mixing can be realized.
  • it is still the same as the conventional method. Therefore, it is extremely difficult to significantly improve the mixing efficiency, and there is still room for improvement.
  • the present invention has been made in view of the above-mentioned problems of the prior art, and its object is to improve mixing efficiency as compared with a conventional static mixer, and to compare with a dynamic mixer having a power unit. It is to provide a static mixer having a mixing efficiency without.
  • the static mixer A liquid inflow port into which two or more kinds of liquids flow, a liquid mixing unit connected to a rear stage of the liquid inflow and mixing the two or more kinds of liquids, and a liquid connected to a rear stage of the liquid mixing unit and mixed.
  • a static mixer having a liquid outlet that flows out,
  • the liquid mixing unit is a substantially cylindrical elongated capillary mixer that mixes the liquid by a turbulent flow with a twisted spiral rod provided inside, and a mixing chamber that is located at a subsequent stage of the capillary mixer and that mixes the liquid that has flowed in inside.
  • the mixing chamber has at least a larger volume than the capillary mixer,
  • the liquid mixing unit is characterized in that at least two turbulent diffusion mixer sections are connected in series.
  • the liquid mixing unit includes a first turbulent diffusion mixer section located on the liquid inlet side, and a second turbulent diffusion mixer section located on the liquid outlet side with respect to the first turbulent diffusion mixer section.
  • a first turbulent diffusion mixer section located on the liquid inlet side
  • a second turbulent diffusion mixer section located on the liquid outlet side with respect to the first turbulent diffusion mixer section.
  • Have The liquid volume of the first turbulent diffusion mixer section is larger than the liquid volume of the second turbulent diffusion mixer section.
  • the liquid mixing unit includes a first turbulent diffusion mixer section located on the liquid inlet side, and a second turbulent diffusion mixer section located on the liquid outlet side with respect to the first turbulent diffusion mixer section.
  • the liquid volume of the first turbulent diffusion mixer section is substantially the same as the liquid volume of the second turbulent diffusion mixer section.
  • the liquid mixing unit includes a first turbulent diffusion mixer section located on the liquid inlet side, and a second turbulent diffusion mixer section located on the liquid outlet side with respect to the first turbulent diffusion mixer section.
  • a first turbulent diffusion mixer section located on the liquid inlet side
  • a second turbulent diffusion mixer section located on the liquid outlet side with respect to the first turbulent diffusion mixer section.
  • Have The liquid volume of the first turbulent diffusion mixer section is smaller than the liquid volume of the second turbulent diffusion mixer section.
  • the liquid mixing unit includes a first turbulent diffusion mixer section located on the liquid inlet side, and a second turbulent diffusion mixer section located on the liquid outlet side with respect to the first turbulent diffusion mixer section.
  • the liquid mixing unit includes a third turbulent flow diffusion mixer section located closer to the liquid outlet than the second turbulent flow diffusion mixer section.
  • the liquid outlet part may be provided with a twisted spiral plate therein, and the twisted spiral plate may further mix the liquid mixed in the liquid mixing unit to flow the liquid out of the static mixer.
  • the static mixer has a switching valve mechanism that switches series connection in a plurality of liquid mixing units, and the liquid volume of the liquid mixing unit is variable by the switching operation of the switching valve mechanism.
  • the static mixer is characterized in that the liquid volume of the liquid mixing unit is variable by connecting at least two turbulent flow diffusion mixer parts to each other by piping.
  • the liquid mixing unit has a characteristic turbulent diffusion mixer section having a capillary mixer and a mixing chamber located at the subsequent stage, and at least two turbulent diffusion mixer sections are connected in series.
  • FIG. 3 is a schematic view of a structure in which a connecting portion between a capillary mixer and a mixing chamber has an angle in the static mixer according to the embodiment of the present invention.
  • FIG. 3 is a schematic view of a static mixer according to an embodiment of the present invention in which a twisted spiral plate is provided at a liquid outlet.
  • FIG. 3 is a schematic view of a static mixer according to an embodiment of the present invention in which a liquid outlet has a porous body.
  • the schematic diagram of another structure provided with the porous body in the static mixer which concerns on this embodiment is shown.
  • FIG 3 is a schematic configuration diagram in the case where three turbulent diffusion mixer sections are connected in series in the static mixer according to the embodiment of the present invention.
  • the schematic block diagram of the modification in the static mixer which concerns on embodiment of this invention is shown.
  • the schematic block diagram of the modification in the static mixer which concerns on embodiment of this invention is shown.
  • the schematic block diagram of the modification in the static mixer which concerns on embodiment of this invention is shown.
  • the schematic block diagram of the modification in the static mixer which concerns on embodiment of this invention is shown.
  • the image figure of the measurement result of the baseline fluctuation and noise by gradient liquid sending is shown.
  • FIG. 1 shows a schematic configuration diagram of a static mixer according to an embodiment of the present invention.
  • the static mixer 10 shown in the figure includes a liquid inlet 12 into which two or more kinds of liquids flow, a liquid mixing unit 14 connected to a subsequent stage of the liquid inlet 12 to mix the two or more kinds of liquids, and the liquid. And a liquid outlet 16 which is connected to the subsequent stage of the mixing unit 14 and through which the mixed liquid flows out.
  • the liquid inlet 12 is provided to allow the liquid from the outside to flow into the static mixer 10.
  • two or more liquid tanks and a liquid flow path from the liquid tank to the liquid inlet 12 are connected to the liquid inlet 12 (not shown).
  • the liquid tanks contain different kinds of liquids, that is, two or more kinds of liquids flow into the liquid inlet 12 from the outside of the static mixer 10.
  • the liquid mixing unit 14 includes a first turbulent diffusion mixer section 20 located on the liquid inlet 12 side and a second turbulent diffusion section located on the liquid outlet 16 side with respect to the first turbulent diffusion mixer section 20.
  • the mixer unit 30 is connected in series. In this embodiment, two or more kinds of liquids are efficiently mixed by utilizing the first turbulent flow diffusion mixer section 20 and the second turbulent flow diffusion mixer section 30 having this characteristic structure.
  • the first turbulent flow diffusion mixer section 20 includes a capillary mixer 22 that mixes two or more kinds of liquids by a turbulent flow with a twisted spiral rod 26 provided inside, and a liquid that is positioned downstream of the capillary mixer 22 and flows into the inside. And a mixing chamber 24 for mixing by diffusion.
  • the capillary mixer 22 is composed of a substantially cylindrical elongated pipe containing stainless steel, PEEK (polyether ether ketone), PTFE (polytetrafluoroethylene), and the like.
  • the inner diameter of the capillary mixer 22 is preferably about 0.25 to 3 mm, particularly preferably about 0.5 to 2 mm, and more preferably about 0.5 to 1 mm. Is.
  • the longitudinal dimension of the capillary mixer is preferably 5 times or more the inner diameter dimension (or outer diameter dimension) thereof.
  • the capillary mixer 22 has a twisted spiral rod 26 inside.
  • the twisted spiral rod 26 in the present embodiment is not limited to such a shape, and may have another shape as long as the liquid can be mixed inside the capillary mixer 22.
  • the capillary mixer 22 in FIG. 1 has a linear elongated shape in the longitudinal direction, the effect of the present invention can be exhibited even if, for example, the capillary mixer 22 includes a curved shape that is bent in the middle in the longitudinal direction. You can
  • the mixing chamber 24 has a substantially cylindrical shape, and has a space inside which a liquid can flow and stay for a predetermined time.
  • the mixing chamber 24 in this embodiment has a substantially cylindrical shape, it may have another shape such as a conical shape, a shape combining a conical shape and a cylindrical shape, or a spherical shape.
  • the mixing chamber 24 has a volume that is at least larger than that of the capillary mixer 22.
  • the mixing chamber 24 preferably has a volume 1.2 times or more that of the capillary mixer 22, more preferably 2 times or more the volume of the capillary mixer 22, and further preferably 5 times. It is preferable to have a volume more than double. Furthermore, it is preferable that the mixing chamber 24 has a shape expanded with respect to the elongated cylindrical capillary mixer 22.
  • the capillary mixer 22 and the mixing chamber 24 are linearly connected, but, for example, as shown in FIG. 3, the connecting portion between the capillary mixer 22 and the mixing chamber 24 is bent upward or in another direction.
  • the connecting portion (the portion where the liquid flows into the mixing chamber 24) has a predetermined angle.
  • the portion where the liquid flows out from the mixing chamber 24 can have a structure having a predetermined angle.
  • the second turbulent flow diffusion mixer section 30 includes a capillary mixer 32 that mixes two or more kinds of liquids by a turbulent flow with a twisted spiral rod 36 provided inside, and a liquid that is positioned downstream of the capillary mixer 32 and flows into the inside. And a mixing chamber 34 that mixes by diffusion.
  • the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section 30 may have the same capacity, or the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section 20 having different capacities.
  • the two-turbulent diffusion mixer section 30 may be connected in series.
  • the capacity of the first turbulent diffusion mixer section 20 is larger than the capacity of the second turbulent diffusion mixer section 30. Further, the capacity of the first turbulent diffusion mixer section 20 can be made smaller than the capacity of the second turbulent diffusion mixer section 30.
  • the fluid outlet 16 allows the liquid mixed efficiently by passing through the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section 30 of the liquid mixing unit 14 to flow out of the static mixer 10. It is provided for.
  • a detector or the like connected in the subsequent stage can be used as a connection port for connecting to the static mixer 10.
  • liquids from the outside are introduced from the liquid inflow port 12, pass through the liquid mixing unit 14 (the first turbulent flow diffusion mixer section 20 and the second turbulent flow diffusion mixer section 30), and are mixed.
  • the liquid is then discharged to the outside via the liquid outlet 16.
  • the static mixer 10 according to this embodiment is configured as described above. Hereinafter, the liquid mixing mechanism in the present embodiment will be described in detail.
  • the liquid mixing unit 14 mixes two or more kinds of liquids.
  • the flow of the liquid inside the liquid mixing unit 14 will be described.
  • two or more kinds of liquids that have flowed in from the liquid inlet 12 reach the capillary mixer 22 included in the first turbulent flow diffusion mixer section 20.
  • the capillary mixer 22 in this embodiment is a substantially cylindrical elongated pipe or the like, and has a twisted spiral rod 26 inside the elongated pipe.
  • the torsion spiral rod 26 is, for example, a rod-shaped stainless steel having a spiral stirring member (see FIG. 2), and the liquid introduced from the liquid inlet 12 passes through the inside of the capillary mixer 22 to generate a turbulent flow. More than one type of liquid is mixed (called primary mixing).
  • the turbulent flow in this specification refers to a flow in which the velocity and pressure of the liquid fluctuate irregularly.
  • the torsion spiral rod 26 in the present embodiment is located in the entire longitudinal direction inside the capillary mixer 22, but for example, it is provided only in a part of the longitudinal direction, or the short torsion spiral rod 26. It is also possible to provide one or more places. Further, the torsion spiral rod 26 may be fixed inside the capillary mixer, or may be provided so that the torsion spiral rod itself can move to some extent inside.
  • the liquid that has been primarily mixed by turbulent flow inside the capillary mixer 22 flows into the mixing chamber 24 located in the subsequent stage.
  • the mixing chamber 24 has a substantially cylindrical shape, and has a space inside which the liquid can flow and stay for a predetermined time.
  • the liquid that is primarily mixed in the capillary mixer 22 is further promoted in the mixing chamber 24 by a diffusion action or a turbulent flow diffusion action (referred to as secondary mixing).
  • Diffusion in this specification means that two or more different types of liquids try to be mixed uniformly.
  • the turbulent flow diffusion in the present embodiment means that the liquid flows into the mixing chamber 24 from the capillary mixer 22 so that the flow velocity of the liquid is slowed, that is, the flow path of the liquid is widened and the flow is disturbed. Means that a mixing effect occurs.
  • the first turbulent flow diffusion mixer section 20 of the present embodiment two or more kinds of liquids are primarily mixed by the turbulent flow by the capillary mixer 22, and in the subsequent stage, the secondary liquid is further diffused by the mixing chamber 24 or turbulent flow diffusion.
  • the first turbulent flow diffusion mixer section 20 included in the liquid mixing unit 14 in the present embodiment improves the mixing efficiency by performing the stepwise mixing.
  • the liquid mixing unit 14 in the present embodiment is provided with a second turbulent flow diffusion mixer section 30 at a stage subsequent to the first turbulent flow diffusion mixer section 20.
  • the second turbulent flow diffusion mixer section 30 may be the same as the first turbulent flow diffusion mixer section 20 as described above, or may have a different shape and capacity.
  • the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section 30 are directly connected, but for example, the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section 30 are connected. It is also possible to provide a liquid channel or the like (for example, a pipe or the like) for appropriately connecting and.
  • the mixing chamber 24 in the first turbulent flow diffusion mixer section 20 can also be expected to utilize the internal space of the mixing chamber 24 to further promote the turbulent flow by the capillary mixer 22 in the preceding stage.
  • the flow of the liquid mixed to some extent by the turbulent flow by the capillary mixer 22 can be irregularly changed and then sent to the second turbulent flow diffusion mixer section 30.
  • the first turbulent diffusion mixer section 20 performs stepwise mixing by the first mixing and the second mixing, and further in the subsequent stage, the second turbulent diffusion mixer section 30 is used to perform stepwise mixing.
  • the third mixing corresponding to the first mixing and the fourth mixing corresponding to the second mixing it is possible to significantly improve the mixing efficiency.
  • the static mixer 10 shown in FIG. 4 can perform stepwise mixing of three stages without adding a new component member, and as a result, the mixing efficiency can be further improved.
  • the liquid outlet 16 may be provided with a porous body 18b having a liquid rectifying effect.
  • the porous body 18b may be arranged inside the liquid outlet 16 or at the outlet of the mixing chamber 34 (on the side of the liquid outlet 16), for example.
  • the porous body 18b in the present embodiment is configured to include a material having a large number of pores.
  • a monolith structure co-continuous structure
  • a sponge structure open cell structure
  • the porous body 18b can be configured to include a metal material such as SUS316 and a polymer material such as PEEK.
  • FIG. 6 shows a schematic diagram of another configuration including a porous body in the static mixer according to this embodiment.
  • a porous body 18b liquid outlet 16
  • the liquid can be further mixed by the secondary mixing after obtaining (the mixed state by the primary mixing).
  • the liquid mixing unit 14 is provided with the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section 30, but as shown in FIG. 7, for example, the third turbulent diffusion mixer section 40 is further provided.
  • the third turbulent diffusion mixer section 40 is further provided.
  • the characteristic structure shown in FIG. 6, that is, the porous body 18b (or the twisted spiral plate 18 shown in FIG. 4) is provided. It can also be provided on the outlet side of the turbulent diffusion mixer section (20, 30, 40).
  • FIG. 8 shows a schematic configuration diagram of a modification of the static mixer according to the embodiment of the present invention.
  • the modification shown in the figure basically has the same components as the static mixer 10 shown in FIG. 7, but in addition to the configuration of FIG. It has a switching valve 50 for switching the series connection of the mixer units (20, 30, 40).
  • each turbulent flow diffusion mixer section has a capillary mixer and a mixing chamber as in FIGS. 1 to 7.
  • the static mixer 10 includes four switching valves 50 inside the liquid mixing unit 14.
  • the switching valve 50 may be, for example, an automatic switching valve that automatically performs the switching operation, or may be a manual switching valve that manually performs the switching operation as needed.
  • the switching valve for switching the plurality of turbulent flow diffusion mixer sections (20, 30, 40) for example, the respective turbulent flow diffusion mixer sections may be connected by pipes.
  • the switching valve 50 is adjusted so that the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section 30 are connected in series (in FIG. 8, the third turbulent diffusion mixer is shown). Part 40 is not connected).
  • the switching valve 50 in the static mixer 10 it is possible to appropriately select the necessary turbulent diffusion mixer section (20, 30, 40) according to the measurement conditions such as component analysis. Can be done.
  • the switching valve 50 it is possible to handle a wide range of analyzes with one static mixer without preparing a plurality of static mixers according to the analysis conditions.
  • the volume of the first turbulent diffusion mixer section 20 is 125 ⁇ l
  • the volume of the second turbulent diffusion mixer section 30 is 240 ⁇ l
  • the volume of the third turbulent diffusion mixer section 40 is 370 ⁇ l, in FIG. It can be used as a static mixer 10 having a capacity of 365 ⁇ l.
  • the switching valve 50 is adjusted so that the second turbulent diffusion mixer section 30 and the third turbulent diffusion mixer section 40 are connected in series to be used as the static mixer 10 having a capacity of 610 ⁇ l. be able to.
  • the switching valve 50 is adjusted so that the first turbulent diffusion mixer section 20 and the third turbulent diffusion mixer section 40 are connected in series to be used as a static mixer having a capacity of 495 ⁇ l. be able to.
  • the switching valve 50 is adjusted so that all of the first turbulent diffusion mixer section 20, the second turbulent diffusion mixer section 30, and the third turbulent diffusion mixer section 40 are connected in series to obtain 735 ⁇ l. It can be used as a static mixer having a capacity of.
  • Fig. 12 shows an image of the measurement results of the baseline fluctuation and mixed noise due to the gradient liquid transfer. As shown in the figure, it can be seen that the amount of mixed noise is the same between the dynamic mixer having the drive unit and the static mixer according to the present measurement after 5 minutes. This indicates that the static mixer has the same mixing efficiency as that of the dynamic mixer in this gradient liquid transfer.
  • the static mixer takes a shorter time to return to the base (the vertical axis strength 0 position at the start of measurement) than the dynamic mixer.
  • the static mixer according to the present embodiment has a better solvent displacing property than the dynamic mixer having the power unit.
  • the static mixer according to this embodiment has excellent mixing efficiency equivalent to that of the dynamic mixer.
  • the liquid mixing unit 14 has a characteristic turbulent diffusion mixer section including a capillary mixer and a mixing chamber located at the subsequent stage, and at least two turbulent diffusion mixers are provided. By connecting the parts in series, the mixing efficiency can be significantly improved as compared with the conventional case.
  • the switching operation of the three turbulent diffusion mixer sections (20, 30, 40) is performed by using the four switching valves.
  • Each turbulent flow diffusion mixer section may be connected to one switching valve so that the capacity of the liquid mixing unit 14 can be switched.
  • the case where two and three turbulent diffusion mixer sections are connected in series has been described. Can be expected to get.
  • the capillary mixer and the mixing chamber are described as separate configurations, but for example, the capillary mixer and the mixing chamber can be integrally manufactured. With such a configuration, it is possible to eliminate the leakage of the liquid and obtain the turbulent diffusion mixer section having high pressure resistance. As a result, it is possible to provide a static mixer having good mixing efficiency and excellent durability.
  • the switching valve is used to perform the switching operation of the turbulent diffusion mixer section.
  • the first turbulent diffusion mixer section 20 and the second turbulent diffusion mixer section are used.
  • each turbulence diffusion mixer unit is arbitrarily selected and connected using a connecting member such as a pipe (20, Even if the static mixer 10 is configured by arbitrarily combining 30 and 40), the same effect as the modification of the present invention can be obtained.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Accessories For Mixers (AREA)
PCT/JP2019/048793 2019-01-17 2019-12-12 スタティックミキサー WO2020149067A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2020566154A JP7343191B2 (ja) 2019-01-17 2019-12-12 液体クロマトグラフィー用スタティックミキサー
EP19910459.7A EP3912710A4 (en) 2019-01-17 2019-12-12 STATIC MIXER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019-005793 2019-01-17
JP2019005793 2019-01-17

Publications (1)

Publication Number Publication Date
WO2020149067A1 true WO2020149067A1 (ja) 2020-07-23

Family

ID=71614366

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2019/048793 WO2020149067A1 (ja) 2019-01-17 2019-12-12 スタティックミキサー

Country Status (3)

Country Link
EP (1) EP3912710A4 (enrdf_load_stackoverflow)
JP (1) JP7343191B2 (enrdf_load_stackoverflow)
WO (1) WO2020149067A1 (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113578091A (zh) * 2021-07-29 2021-11-02 浙江华晨环保有限公司 微阻力管道混合器

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6031329U (ja) * 1983-08-03 1985-03-02 株式会社ワイ　ケイ　エス 混合器
JPS6224933U (enrdf_load_stackoverflow) * 1985-07-26 1987-02-16
JPH01257268A (ja) * 1987-08-27 1989-10-13 Biotrack Inc 液体サンプルの稀釈及び混合のための装置及び方法
US5076705A (en) * 1990-08-01 1991-12-31 Texaco, Inc. Static mixing system with high turndown ratios to minimize pressure drops
JP2005034750A (ja) 2003-07-15 2005-02-10 Noritake Co Ltd 流体攪拌装置
JP2007132873A (ja) * 2005-11-11 2007-05-31 Nippon Soda Co Ltd 分析方法、分離方法、ミキサ、及び分析装置
US20090308472A1 (en) * 2008-06-15 2009-12-17 Jayden David Harman Swirl Inducer
JP2011083763A (ja) 2009-09-18 2011-04-28 Kurita Water Ind Ltd 流体混合装置及び方法
JP2011104482A (ja) * 2009-11-13 2011-06-02 Asahi Organic Chemicals Industry Co Ltd 静止型流体混合器及び静止型流体混合器を用いた装置
JP2018514761A (ja) * 2015-03-31 2018-06-07 ウオーターズ・テクノロジーズ・コーポレイシヨン マルチ注入モードバルブモジュール
JP2019005793A (ja) 2017-06-28 2019-01-17 株式会社栗本鐵工所 ベンディングロール

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
GB2368299B (en) * 2000-10-24 2004-04-21 William Thomas Dennis Bates Capillary tube
KR101007834B1 (ko) * 2010-07-01 2011-01-13 금호환경 주식회사 멀티 오존 믹서 및 이를 이용한 수처리 장치
EP3030540B1 (en) * 2013-08-06 2018-04-11 Oxea Bishop LLC Improved manufacture of methylolalkanes
US10758927B2 (en) 2015-12-23 2020-09-01 Commonwealth Scientific And Industrial Research Organisation Rotary device
CN207025118U (zh) 2017-06-29 2018-02-23 广州环投环境服务有限公司 一种离心脱水机螺旋管混合器

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6031329U (ja) * 1983-08-03 1985-03-02 株式会社ワイ　ケイ　エス 混合器
JPS6224933U (enrdf_load_stackoverflow) * 1985-07-26 1987-02-16
JPH01257268A (ja) * 1987-08-27 1989-10-13 Biotrack Inc 液体サンプルの稀釈及び混合のための装置及び方法
US5076705A (en) * 1990-08-01 1991-12-31 Texaco, Inc. Static mixing system with high turndown ratios to minimize pressure drops
JP2005034750A (ja) 2003-07-15 2005-02-10 Noritake Co Ltd 流体攪拌装置
JP2007132873A (ja) * 2005-11-11 2007-05-31 Nippon Soda Co Ltd 分析方法、分離方法、ミキサ、及び分析装置
US20090308472A1 (en) * 2008-06-15 2009-12-17 Jayden David Harman Swirl Inducer
JP2011083763A (ja) 2009-09-18 2011-04-28 Kurita Water Ind Ltd 流体混合装置及び方法
JP2011104482A (ja) * 2009-11-13 2011-06-02 Asahi Organic Chemicals Industry Co Ltd 静止型流体混合器及び静止型流体混合器を用いた装置
JP2018514761A (ja) * 2015-03-31 2018-06-07 ウオーターズ・テクノロジーズ・コーポレイシヨン マルチ注入モードバルブモジュール
JP2019005793A (ja) 2017-06-28 2019-01-17 株式会社栗本鐵工所 ベンディングロール

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113578091A (zh) * 2021-07-29 2021-11-02 浙江华晨环保有限公司 微阻力管道混合器
CN113578091B (zh) * 2021-07-29 2023-12-19 浙江华晨环保有限公司 微阻力管道混合器

Also Published As

Publication number Publication date
EP3912710A1 (en) 2021-11-24
JP7343191B2 (ja) 2023-09-12
JPWO2020149067A1 (enrdf_load_stackoverflow) 2020-07-23
EP3912710A4 (en) 2022-10-26

Similar Documents

Publication Publication Date Title
US5887977A (en) Stationary in-line mixer
US8979358B2 (en) Mixing device for liquid chromatography
US20130128688A1 (en) Flow Reversing Static Mixer and Method
WO2020149067A1 (ja) スタティックミキサー
JP5106918B2 (ja) インラインミキサー構造
CN106102888A (zh) 用于使至少两种液体的混合物均匀化的静态混合器以及设有这种混合器的配料装置
JP6276603B2 (ja) 混合装置
JPWO2020149067A5 (enrdf_load_stackoverflow)
JPH05123553A (ja) 流体と液体を混合する装置、特に水を含んだ飲料に二酸化炭素を混入する装置
JP2011121038A (ja) スタティックミキサー
US6843262B2 (en) Fluidic switches and methods for controlling flow in fluidic systems
US20240149228A1 (en) Static mixer
CN114159998B (zh) 试剂混合装置及液相色谱仪
WO2020105274A1 (ja) スタティックミキサー
CN110787714B (zh) 一种液相色谱仪用微型高压静态混合器
JP3241869U (ja) グラジエントミキサー
CN110756073B (zh) 一种化工液体分流螺旋对冲混合器
CN213050149U (zh) 超宽混合比静态混合器
CN214715770U (zh) 一种流体分配混合器
EP0377202A2 (en) Method and mixing device for small volumes
RU2622414C1 (ru) Устройство смешения жидкости и газа
CN212369990U (zh) 一种乳化切削液调配装置
KR102438422B1 (ko) 유체 혼합용 챔버
JP2023506562A (ja) バイオプロセス流体混合システム
CN111070688A (zh) 一种多流体混合3d打印装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19910459

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2020566154

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2019910459

Country of ref document: EP

Effective date: 20210817