WO2020095099A1

WO2020095099A1 - Cosmetic oral care product

Info

Publication number: WO2020095099A1
Application number: PCT/IB2018/059200
Authority: WO
Inventors: Илья ГЕРЧИКОВ; Ольга ЛАНДО; Рита ПЛЯВНИЕЦЕ
Original assignee: Акцию Сабиедриба "Дзинтарс"
Priority date: 2018-11-09
Filing date: 2018-11-22
Publication date: 2020-05-14
Also published as: LV15495A

Abstract

The proposed invention relates to the field of cosmetic oral care products. The claimed product contains a special complex comprising methyl salicylate, anethole, essential oils of eucalyptus, mint and sweet orange, which has antimicrobial activity and inhibits growth of Streptococcus mutans and Lactobacillus acidophilus, which cause the occurrence of caries and inflammatory processes in the oral cavity. The product further comprises a complex of remineralising ingredients, namely calcium, magnesium, potassium and sodium ions and plant extracts comprising microelements having remineralising activity, which restore tooth enamel and reduce tooth sensitivity. A composition of plant extracts of aloe leaves and bearberry, oak bark, rowanberry and sea buckthorn berry, hair grass root, cloves and camomile reduces inflammation and bleeding of the gums and disinfects the oral cavity, thereby improving gum condition.

Description

COSMETIC Oral Care

The invention relates to medicine, namely to dentistry, to means for the care of teeth and oral cavity.

It is known from the prior art that for the prevention and remineralizing therapy of the initial forms of caries, solutions of calcium salts are used, as well as preparations containing a complex of macro- and microelements having anti-carious effects, for example, Remodent powder. The drug "Remodent" consists of trace elements of calcium, magnesium, potassium, sodium, chlorine and is available in the form of a white amorphous powder, from which 2.5-3% solutions are prepared. The specified powder is used in the form of applications and introduced into the hard tissues of the tooth using electrophoresis. After electrophoresis or application, cotton swabs moistened with 1-2% sodium fluoride solution are applied to the treated teeth for 2-3 minutes. This contributes to the fixation of calcium salts in the tissues of the tooth. The disadvantage of this drug is the mandatory use of physical methods (electrophoresis) for the deposition of drugs in the hard tissues of the tooth. It should be noted that this tool is a product of animal origin and is not acceptable for use by vegetarians and vegans.

Known toothpastes, which include powder "Remodent", (patents LV 12066, application. 11.12.1996, MKI A61K7 / 26, patent LV12037, application. 15.11.1996, MKI A 61 K7 / 28, patent RU2361544 (C2) , Declared 10.10.20.08, MKI A61C 5/00.

Also known is a composition for the prevention and treatment of diseases of the oral cavity and the care of teeth and oral cavity (RF patent N ° 2 180 555, A61K 7/26, 2000). This composition is an aqueous extract of herbs of chamomile pharmacy, Hypericum perforatum, dried marshmallow, Echinacea purpurea, medicinal sage leaves, common oak bark, and calamus swamp. The disadvantage of this tool is the low antibacterial and anti-inflammatory effect. Also known is the patent of the Russian Federation N ° 2 355 380 (13) Cl, “Dental Elixir”, MKI A61K 8/18, A61K 8/97 (declared. 11.01.2008). The specified tool is used for the prevention and treatment of initial forms of dental caries and contains glycerin, ethyl alcohol, sodium fluoride, calcium hydroxyapatite, desorbent pectin, plant extracts of leaves of coltsfoot, and laurel noble, essential oils of peppermint, ball eucalyptus and water taken in a specific ratio. The above-described dental elixir prevents the formation of plaque and plaque, has remineralizing, anti-carious, cleansing and deodorizing effects. However, it is not effective enough in the case of remineralization and restoration of tooth enamel, as it contains an insufficient amount of the ingredients intended for this (salts of potassium and magnesium ions, extracts of medicinal plants).

The use for various purposes of various compositions for the remineralization of tooth enamel (EP1809233 (B1) - application. 2015-12-23, fluoride varnishes, polymerization varnishes and films also requires specialized dental care, which should be carried out only in a dental office.

The closest in technical essence is “Gel for remineralization of tooth enamel”, (RF patent, N ° RU2403007, application form 10.22.2009, MKI A61K6 / 00), which contains a remineralizing complex in the form of calcium, magnesium, sodium and potassium salts, structure-forming base, and water. The structure-forming - gel-forming base is formed by the sodium salt of carboxymethyl cellulose, its remineralizing composition includes calcium chloride, magnesium chloride or magnesium sulfate, sodium chloride, sodium dihydrogen phosphate, potassium hydrogen phosphate, potassium dihydrogen phosphate and, in addition, urea is introduced into the gel composition, the gel ensures its physiology high mineralizing properties, allows you to use the gel to treat children.

However, it is not effective enough in case of strengthening the gums, reducing their inflammation and bleeding, as it contains an insufficient amount of the ingredients intended for this (extracts of medicinal plants). The aim of the invention is the creation of a highly effective means for caring for the oral cavity in the form of various products - a tooth elixir (mouth rinse), toothpaste or gel-like toothpaste, intended for a wide range of users, providing antimicrobial action that inhibits the growth of bacteria responsible for the occurrence caries and inflammatory processes in the oral cavity, enhanced remineralizing effect and reducing inflammation and bleeding of the gums, improving the condition of the gums with p riodontite.

The inventive cosmetic product for caring for the oral cavity, containing a remineralizing complex in the form of salts of calcium, magnesium, sodium and potassium, a structure-forming base, and water, additionally contains an antimicrobial complex, plant extracts, menthol and preservative. As a remineralizing complex, it contains a complex of calcium, magnesium, potassium and sodium ions contained in sodium fluoride and / or calcium chloride, calcium glycerophosphate, magnesium chloride, potassium chloride, sodium chloride and EDTA disodium salt. As an antimicrobial complex, the product contains methyl salicylate, anethole, essential oils of eucalyptus, peppermint, sweet orange, clove essential oil and / or clove extract. As plant extracts, plant extracts of sage and / or aloe leaves, oak bark, rowan fruits, calamus rhizomes, bearberry leaves, chamomile flowers and sea buckthorn fruits have been introduced. To obtain a tooth elixir, toothpaste or gel-like toothpaste as a structure-forming base, the claimed agent contains sorbitol and / or sodium carboxymethyl cellulose and / or hydrated silicon dioxide and / or polyvinylpyrrolidone. To improve consumer properties and appearance, sodium lauryl sulfate and / or polysorbate 80, colorants and flavoring are additionally introduced into the claimed product.

The inventive cosmetic product contains these components in the following proportions, wt%

Menthol 0.05-0.20 Eucalyptus essential oil 0.1-0.5

Methyl salicylate 0.05-0.25

Anetol 0.01-0.05

Sweet Orange Essential Oil 0.01-0.25

Peppermint essential oil 0.01-1.5

Clove essential oil and / or extract

0.01-0.5 cloves

Extract of sage and / or aloe leaves 1.0-5.0 Extract of oak bark 0.5-2.O Extract of calamus rhizome 0.5-2.O Extract of chamomile flowers 0.5-2.0 Extract of rowan fruit 0.5-2.0 Extract of bearberry leaves 0.1-2. O Sea buckthorn fruit extract 0.1-2. О Sodium saccharinate 0.01-0.25 Disodium salt of EDTA 0.1-0.2 Calcium chloride 0.1-1.0 Magnesium chloride 0.05-1.0

Sodium fluoride and / or potassium chloride 0.001-0.55

Sodium chloride 0.1-0.9 Calcium Glycerophosphate 0.1-1.0

Preservative (ethyl alcohol and / or sodium

0.10 -30.0

benzoate)

Dyes 0.001-1.15

Sorbitol and / or Sodium Carboxymethyl

cellulose and / or polyvinylpyrrolidone and / or 0.10-30.0

hydrated silicon dioxide

Sodium lauryl sulfate and / or Polysorbate 80 0.5-4.0

Water Else

The inventive tool contains a special complex consisting of methyl salicylate, anethole, essential oils of eucalyptus, peppermint, sweet orange, clove essential oil and / or clove extract, which has antimicrobial properties and inhibits the growth of Streptococcus mutans and Lactobacillus acidophilus, responsible for the occurrence of caries and inflammatory caries the oral cavity.

In the inventive tool used reproduced powder composition Remodent (animal powder, obtained earlier from the bones of young cattle, containing ions of calcium, magnesium, potassium, sodium, phosphorus, chlorine, as well as manganese, iron, zinc, copper and trace elements). For this, a complex of mineral salts of non-animal origin (calcium chloride, magnesium chloride, potassium chloride, sodium chloride, calcium glycerophosphate) and extracts of medicinal plants containing manganese, iron, zinc, copper and trace elements were used. The remineralizing complex can be supplemented with sodium fluoride, which helps to reduce tiny damage to the tooth enamel and make the teeth more resistant to destruction.

A specially selected composition of plant extracts of aloe leaves, oak bark, rowan and sea buckthorn fruits, calamus rhizomes, chamomile flowers and bearberry leaves reduces inflammation and bleeding of the gums, strengthens them and disinfects the oral cavity, improving the condition of the gums during periodontitis. As plant extracts, the product may also contain sage. Depending on the type of product - tooth elixir, toothpaste or gel-like toothpaste - a cosmetic product may contain various colorants, a flavoring agent and a structure-forming base.

Characterization of input components

Menthol (Menthol) gives mint freshness, stimulates the cold receptors of the mucous membranes, a weak antiseptic, has a mild antibacterial effect. Introduced in the amount of 0.05 - 0.2%

Eucalyptus essential oil (Eucalyptus Globulus Leaf Oil) has anti-inflammatory, wound healing, local anesthetic, as well as astringent and tonic properties. It has microbiological activity against gram-positive, gram-negative microorganisms, has a detrimental effect on fungi and protozoa, which is due to the bactericidal effect. Introduced in the amount of 0.1 - 0.5%

Methyl Salicylate (Methyl Salicylate) is a methyl ester of salicylic acid. Used as an antiseptic, anti-inflammatory and analgesic. Introduced in the amount of 0.05 - 0.25%

Anethol (Anethol) - a component of the essential oils of anise, fennel, star anise, etc. It is used as an antiseptic and flavor. Introduced in the amount of 0.01 - 0.05%

Sweet Orange Essential Oil (Citrus Aurantium Dulcis (Orange) Peel Oil) - soothes, refreshes, tones. How is an antiseptic used for oral ulcers. It has anti-inflammatory effect. Introduced in the amount of 0.01 - 0.25%

Peppermint essential oil (Mentha Arvensis Herb Oil and / or Mentha Viridis Leaf Oil and / or Mentha Spicata Herb Oil) - has a tonic, refreshing, deodorizing, antiseptic and analgesic effect. Widely used in toothpastes. It is rich in compounds with high antibacterial activity, indicated for use in the treatment of wounds. Introduced in the amount of 0.01 - 1.5%

Clove essential oil (Eugenia Caryophyllus Leaf Oil) and / or clove extract (Eugenia Caryophyllus Bud Extract) have anti-inflammatory effects and are used as a bactericidal and fungicidal component in toothpaste formulations. Introduced in the amount of 0.01 - 0.5%

The combination of abrasive polishing components of silicon, calcium glycerophosphate and a special antimicrobial complex consisting of methyl salicylate, anethole, essential oils of eucalyptus, peppermint, sweet orange, cloves and / or clove extract not only effectively removes plaque, but also prevents the formation of bacterial plaque, and polishes enamel, returning natural whiteness to teeth. Sage leaf extract (Salvia Officinalis Leaf Extract) has an astringent, antibacterial, antiseptic, anti-inflammatory effect. Introduced in the amount of 1.0 - 5.0%

Aloe leaf extract (Aloe Barbadensis Leaf Extract) has a pronounced moisturizing, anti-inflammatory, regenerating, bacteriostatic effect. It enhances the regeneration processes and increases the body's defenses. As a stimulant of adaptive and protective reactions, it is widely used to enhance regenerative processes in injuries and slowly healing wounds. It is used to treat long-term non-healing wounds and ulcers, with inflammatory diseases of the oral cavity. Introduced in the amount of 1.0 - 5.0%

Oak bark extract (Quercus Robus Bark Extract) has astringent and antiseptic properties. Used as part of preventive toothpastes against bleeding gums. Effective as an anti-inflammatory agent for diseases of the oral cavity, it is used as a blood vessel strengthening agent. Introduced in the amount of 0.5-2.0%

Calamus Root Extract (Acorus Calamus Root Extract) has a tonic, anti-inflammatory, fungicidal effect. It is used for bleeding gums, with inflammation of the mucous membrane of the oral cavity and gums. Introduced in the amount of 0.5-2.0%

Chamomilla Recutita Flower Extract has bactericidal, anti-inflammatory, sedative, analgesic and wound healing properties. It is used for inflammatory diseases of the oral cavity and for fungal inflammations of the oral mucosa. Introduced in the amount of 0.5 - 2.0%

Rowan fruit extract (Sorbus Aucuparia Fruit Extract) has a bactericidal effect and is used in the treatment of wounds. It has a positive effect in periodontal diseases. Introduced in the amount of 0.5-2.0%

Bearberry leaf extract (Arctostaphylos Uva Ursi Leaf Extract) has an antiseptic and anti-inflammatory effect. Included in the treatment of periodontitis. Introduced in the amount of 0.1-2.0%

Sea buckthorn fruit extract (Hippophae Rhamnoides Fruit Extract) has an epithelizing and anesthetic effect. It has antibacterial properties, has high biological activity, helps to accelerate epithelization and has a stimulating effect on wound healing. Helps with lesions of the oral mucosa. Introduced in the amount of 0.1-2.0%

The complex of plant extracts has bactericidal, antiseptic, anti-inflammatory, sedative, analgesic and wound healing properties, and also contains manganese, iron, zinc and trace elements necessary for remineralization of dental tissue.

Ethyl alcohol and / or sodium benzoate were introduced into the agent as a preservative in an amount of 0.1–20.0%.

Ethyl alcohol (Alcohol) - wine alcohol, ethanol, is widely used in cosmetics and perfumes as a solvent, preserving, disinfecting and drying additive.

Sodium benzoate (Sodium Benzoate) - sodium salt of benzoic acid, an antiseptic and preservative in toothpastes. Registered as food supplement E211.

A flavoring supplement, such as sodium saccharin (Sodium Saccharin), is an artificial sugar substitute. In cosmetics, it is used to sweeten toothpastes, elixirs. Registered as food supplement E954. Introduced in the amount of 0.01-0.25%

Disodium EDTA (Disodium EDTA) - disodium salt of ethylenediaminetetraacetate, complexing agent. It forms strong complexes with metal cations, prevents precipitation and retains metal salts, primarily magnesium and calcium, in dissolved bio-digestible form. Introduced in the amount of 0.1 - 0.2%

Calcium Chloride (Calcium Chloride) compensates for the deficiency of calcium ions. It has anti-inflammatory effect. It is a natural component of saliva. Participates in the remineralization and restoration of tooth enamel. Introduced in the amount of 0.1-1.0%

Magnesium Chloride (Magnesium Chloride) has an anti-inflammatory and astringent effect. It activates alkaline phosphatase, provides a mineralizing function of saliva. In addition, magnesium chloride directly affects biomineralization by changing the size and orientation of enamel hydroxyapatite crystals. Introduced in the amount of 0.05-1.0%

Sodium fluoride (Sodium Fluoride) and Potassium Chloride (Potassium Chloride) introduced into the composition in an amount of 0.001-0.55%

Sodium fluoride (Sodium Fluoride) is used in toothpastes as an active additive for the prevention of caries, as well as a disinfectant and preservative component. Fluoride prevents the development of caries, helping to strengthen tooth enamel.

Potassium Chloride reduces the sensitivity of tooth tissue. Potassium ions are deposited on the surface of the nerve fiber, block the nerve impulse, so that the feeling of pain disappears. It is used in dental products for people with hypersensitivity of teeth. Sodium Chloride (Sodium Chloride) - is a natural component of saliva. Introduced in the amount of 0.1- 0.9%

Calcium glycerophosphate (Calcium Glycerophosphate) has a remineralizing effect. Strengthens tooth enamel, providing caries prevention. Introduced in the amount of 0.1-1.0%

The combination in the declared relations of calcium chloride, calcium glycerophosphate, sodium fluoride and / or potassium chloride, sodium chloride, magnesium chloride imitates the natural electrolyte composition of saliva, maintains the natural equilibrium in the saliva of calcium, sodium, magnesium and potassium ions directly involved in the enamel remineralization process. In this case, calcium glycerophosphate is a source of phosphorus in the composition of the tooth elixir, toothpaste or tooth gel. The mineral salts used are not animal products.

As dyes, CI 42090, CI 19140 and CI 77891 were introduced into the composition, in an amount of 0.001- 1.15%

Dye (CI 42090), is a synthetic aniline blue dye used to color cosmetics. It has strong antiseptic properties. Registered as food supplement E 133.

Dye (CI 19140) - yellow dye, a product of the processing of coal. It is applied in the food and cosmetic industry. Registered as food supplement E 162.

Dye (CI 77891) - titanium dioxide, white inorganic pigment. In cosmetic production, highly purified and finely dispersed titanium dioxide is used, which has a high hiding power, coloring and opalescent effect. Registered as food supplement E 171.

Sorbitol (Sorbitol) and / or Sodium carboxymethyl cellulose (Cellulose Gum) and / or Hydrated Silica (Hydrated Silica) and / or Polyvinylpyrrolidone (PVP) have been introduced as a structure-forming base. Introduced in the amount of 0.1-30.0%

Sorbitol (Sorbitol) is an aliphatic alcohol with a sweet taste. It is used in cosmetics as a moisturizing component, significantly affects the texture of the product, giving it special softness, plasticity and velvety. Registered as food supplement E420.

Sodium carboxymethyl cellulose (Cellulose Gum) - a hydrocoloid, has emulsifying, thickening, foaming, stabilizing, softening, gelling and film-forming properties. Hydrated Silica (Hydrated Silica) - a weak abrasive, a thickener, has a soft, gentle effect.

Polyvinylpyrrolidone (PVP) is a thickener and gelling agent.

Sodium Lauryl Sulfate (Sodium Lauryl Sulfate) and Polysorbate 80 (Polysorbate 80) are introduced in the amount of 0.5 - 4.0%

Sodium lauryl sulfate (Sodium Lauryl Sulfate) has a pronounced cleansing and foaming ability.

Polysorbate 80 (Polysorbate 80) - nonionic surfactant, emulsifier, solubilizer.

The proposed boundaries of the quantitative ratios of the introduced components provide the creation of liquid (elixir, rinse) and thick (toothpastes or gels) products for the care of the oral cavity and teeth. As a result, cosmetics obtained on the basis of the claimed composition of the components have high physicochemical parameters for stability, appearance, and also have a highly effective effect on inhibiting bacterial growth, preventing and treating caries, and strengthening tooth enamel and gums.

Inhibition of the growth of Streptococcus mutans and Lactobacillus acidophilus, responsible for the occurrence of plaque, caries and inflammatory processes in the oral cavity is achieved by enhancing the synergistic effect of the use of a special complex consisting of methyl salicylate, anethole, essential oils of eucalyptus, peppermint and sweet orange.

Remineralization and restoration of tooth enamel, neck of teeth and reduction of tooth sensitivity is achieved by a special complex of components, not of animal origin, but specially composed of calcium, magnesium, potassium, sodium ions, as well as from a number of plant extracts containing manganese, iron, zinc, copper and trace elements.

Reducing inflammation and bleeding of the gums is achieved by a combination of extracts of aloe leaves or sage, oak bark, rowan and sea buckthorn fruits, calamus rhizomes, chamomile flowers, cloves and bearberry leaves. Strengthening gums is achieved by a combination of extracts of oak bark, fruits of mountain ash and sea buckthorn, calamus rhizomes.

As examples of the use of the claimed cosmetic products below are the formulations of cosmetic products for various purposes. The effectiveness of the products of the claimed composition was proved by instrumental method, clinical trials and consumer testing.

The recipes are based on the preparation of 100 kg of the finished product. Example 1. Dental elixir

Ethyl alcohol 5,000

Menthol 0.050

Sorbitol 0.100

Polysorbate 80 0.500

Eucalyptus Essential Oil 0.150

Methyl salicylate 0.050

Anethol 0.015

Sweet Orange Essential Oil 0.010

Peppermint essential oil 0.015

Aloe Leaf Extract 1,000

Clove Extract 0.100

Oak Bark Extract 0.750

Calamus Rhizome Extract 1,000

Chamomile Flower Extract 0.750

Rowan fruit extract .500

Bearberry leaf extract .100

Sea buckthorn fruit extract 0.150

Sodium Benzoate 0.100

Sodium saccharinate 0.250

Disodium EDTA 0,100

Calcium Chloride 1,000

Magnesium Chloride 1,000

Potassium chloride .500

Sodium Chloride 0.900

Calcium Glycerophosphate 0.100

Dye CI 42090 0.001

Water 85,809

100,000

The tool is prepared as follows.

Auxiliary solutions and compositions are preliminarily prepared: an aqueous solution of disodium EDTA; aqueous dye solution CI 42090; composition of mineral salts and additives: (calcium chloride, magnesium chloride, potassium chloride, sodium chloride, calcium glycerophosphate, sodium benzoate, sodium saccharin, aloe leaf extract).

composition of essential oils and extracts of medicinal plants: (eucalyptus oil, orange oil, peppermint oil, menthol, methyl salicylate, anethole, oak bark extract, calamus rhizome extract, chamomile flower extract, mountain ash fruit extract, clove extract, bearberry leaf extract, sea buckthorn fruit extract, polysorbate 80).

To prepare the tooth elixir, the following are sequentially loaded into the reactor: purified water (minus the amount for the preparation of aqueous solutions); an aqueous solution of disodium EDTA; composition of mineral salts and additives; sorbitol.

The liquid is stirred for 10-20 minutes. until complete dissolution of the composition of mineral salts and additives. Ethyl alcohol is then charged into the reactor. The liquid is stirred for 5-10 minutes. and load the composition of essential oils and extracts of medicinal plants and an aqueous solution of the dye CI 42090. The liquid is stirred for 1 to 2 hours. Stand for at least 3 days and filter.

The prepared tooth elixir is checked for compliance with organoleptic and physico-chemical indicators: appearance, color, smell, taste, pH, density, mass fraction of ethyl alcohol, volume fraction of ethyl alcohol. If the indicators comply with the norm, the dental elixir is served on the packaging.

The tooth elixir is a homogeneous transparent liquid of light green color with a fresh, pleasant smell with notes of mint and eucalyptus and a pleasant taste characteristic of this appellation.

Example 2 Dental Elixir

Ethyl alcohol 29,000

Menthol 0.200

Sorbitol 10,000

Polysorbate 80 2,000

Eucalyptus Essential Oil 0.350

Methyl Salicylate 0.200

Anethol 0.050

Sweet Orange Essential Oil .00

Peppermint essential oil 1,500

Sage Extract 5,000

Clove extract .500

Oak Bark Extract 2,000

Calamus Rhizome Extract 1,750

Chamomile Flower Extract 2,000

Rowan Fruit Extract 2,000

Bearberry Leaf Extract 2,000

Sea buckthorn fruit extract 2,000

Sodium Benzoate 1,000 Sodium saccharinate 0.010

Disodium EDTA 0.125

Calcium Chloride 0.100

Magnesium Chloride 0.050

Potassium chloride 0.001

Sodium Chloride 0.100

Calcium Glycerophosphate 1,000

Dye CI 42090 0.050

Water 36.814

100,000

A dental elixir is prepared as described in Example 1. The elixir is a homogeneous liquid of light green color with a fresh, pleasant smell with notes of mint and eucalyptus and a pleasant taste characteristic of this appellation.

Example 3 Gel Toothpaste

Sorbitol 4,000

Sodium Carboxymethyl Cellulose 1,000

Polyvinylpyrrolidone 0.100

Sodium Benzoate 0.100

Disodium EDTA 0,100

Hydrated silica 15,000

Eucalyptus Essential Oil .500

Methyl salicylate 0.050

Anethol 0.010

Sweet Orange Essential Oil 0.010

Peppermint essential oil 0.010

Menthol 0.050

Aloe Leaf Extract 1,000

Clove Extract 0.050

Oak bark extract .500

Calamus Rhizome Extract 2,000

Chamomile Flower Extract 0.750

Rowan fruit extract .500

Bearberry leaf extract .100

Sea buckthorn fruit extract .100

Polysorbate 80 0.500

Sodium Lauryl Sulfate 1,000 Sodium saccharinate 0.015

Calcium Chloride 0.100

Magnesium Chloride 0.950

Potassium chloride 0.001

Sodium Chloride 0.900

Calcium Glycerophosphate 0.100

Sodium Fluoride 0.250

Dye CI 42090 0.010

Dye CI 19140 0.010

Dye CI 77891 0.50

Water 69,734

100,000

The tool is prepared as follows.

Auxiliary solutions and compositions are pre-prepared: - aqueous solutions of disodium salt of EDTA, dye CI 42090, dye CI 19140, sodium lauryl sulfate, sodium fluoride; - composition of mineral salts and additives: (calcium chloride, magnesium chloride, potassium chloride, sodium chloride, calcium glycerophosphate, sodium benzoate, sodium saccharinate, aloe extract; - composition of essential oils and extracts of medicinal plants (eucalyptus oil; orange oil; peppermint oil; menthol; methyl salicylate, anethole; clove extract, oak bark extract; calamus rhizome extract; chamomile flower extract; mountain ash fruit extract; bearberry leaf extract; sea buckthorn fruit extract; polysorbate 80).

To prepare a gel-like toothpaste, the following are sequentially loaded into the reactor:

- purified water (minus the amount for the preparation of aqueous solutions); sorbitol; an aqueous solution of disodium EDTA; composition of mineral salts and additives; aqueous solution of sodium fluoride. Mix and homogenize.

Then, titanium dioxide dye (CI 77891) is charged to the reactor. Mix and homogenize. Gelling agents are loaded - polyvinylpyrrolidone; mix and homogenize; sodium carboxymethyl cellulose; mix and homogenize.

A thickener, hydrated silica, is charged in portions. Mix and homogenize.

Then, the following is loaded into the reactor: a composition of essential oils and extracts of medicinal plants; peppermint oil; aqueous dye solution CI 42090; an aqueous solution of the dye CI 19140. Mix and homogenize. Next, an aqueous solution of sodium lauryl sulfate is charged to the reactor. Mix and homogenize. The mass is evacuated and cooled to a temperature of 30 ± 2 ° C. The prepared mass of toothpaste is checked for compliance with organoleptic and physico-chemical indicators: appearance, color, smell, taste, pH.

If the indicators correspond to the norm, the toothpaste is packaged.

Toothpaste is a homogeneous gel-like mass of light green color with a fresh, pleasant smell with notes of mint and eucalyptus and a pleasant taste characteristic of this appellation.

Example 4. Gel toothpaste

Sorbitol 7,000

Sodium Carboxymethyl Cellulose 2,500

Polyvinylpyrrolidone 0.500

Sodium Benzoate 0.500

Disodium salt EDTA 0,200

Hydrated silica 20,000

Eucalyptus Essential Oil 0.100

Methyl salicylate 0.250

Anethol 0.050

Sweet Orange Essential Oil 0.250

Peppermint essential oil 1,250

Menthol 0.200

Aloe Leaf Extract 3,000

Clove Extract 0.250

Oak Bark Extract 2,000

Calamus Rhizome Extract .500

Chamomile Flower Extract 2,000

Rowan Fruit Extract 1,000

Bearberry Leaf Extract 1,500

Sea buckthorn fruit extract 1,000

Polysorbate 80 1,500

Sodium Lauryl Sulfate 1.750

Sodium saccharinate 0.250

Calcium Chloride 0.750

Magnesium Chloride 0.050

Potassium chloride .500

Sodium Chloride 0.100

Calcium Glycerophosphate 0.850

Sodium Fluoride 0.050

Dye CI 42090 0.030

Dye CI 19140 0.085

Dye CI 77891 0.800 Water 49.235

100,000

Toothpaste is prepared in the same way as described in example 5. It is a homogeneous gel-like mass of light green color with a fresh, pleasant smell with notes of mint and eucalyptus and a pleasant taste characteristic of this appellation.

Example 5 Toothpaste

Sorbitol 3,000

Sodium Carboxymethyl Cellulose 1,000

Polyvinylpyrrolidone 0.100

Sodium Benzoate 0.100

Disodium EDTA 0,100

Hydrated silica 20,000

Eucalyptus Essential Oil 0.150

Methyl salicylate 0.050

Anethol 0.015

Sweet Orange Essential Oil 0.010

Peppermint essential oil .100

Menthol 0.075

Aloe Leaf Extract 1,000

Clove Extract 0.010

Oak Bark Extract 0.750

Calamus Rhizome Extract 1,000

Chamomile Flower Extract .500

Rowan fruit extract .500

Bearberry leaf extract .100

Sea buckthorn fruit extract 0.150

Polysorbate 80 0.500

Sodium Lauryl Sulfate 1,000

Sodium saccharinate 0.050

Calcium Chloride 0.100

Magnesium Chloride 1,000

Potassium chloride 0.001

Sodium Chloride 0.900

Calcium Glycerophosphate 0.100

Sodium Fluoride 0.300

Dye CI 42090 0.005

Dye CI 19140 0.001

Dye CI 77891 0.300 Water 67.033

100,000

Toothpaste is prepared as follows

Auxiliary solutions and compositions are pre-prepared: -aqueous solutions of disodium EDTA disodium salt, CI 42090 dye, CI 19140 dye, sodium lauryl sulfate, sodium fluoride, - a composition of mineral salts and additives: (calcium chloride, magnesium chloride, potassium chloride, sodium chloride, calcium glycerophosphate, sodium benzoate, sodium saccharinate, aloe leaf extract; - composition of essential oils and extracts of medicinal plants (eucalyptus oil; orange oil; peppermint oil; menthol; methyl salicylate, anethole; clove extract; core extract oak; extract of calamus rhizome; extract of chamomile flowers; rowan fruit extract; bearberry leaf extract; sea buckthorn fruit extract; polysorbate 80).

To prepare the toothpaste in the reactor sequentially load:

- purified water (minus the amount for the preparation of aqueous solutions); sorbitol; an aqueous solution of disodium EDTA; composition of mineral salts and additives; aqueous solution of sodium fluoride. Mix and homogenize. Then titanium dioxide (CI 77891) is charged into the reactor. Mix and homogenize. Abrasive, hydrated silicon dioxide, is loaded in parts. Mix and homogenize. The gelling agents are loaded: - polyvinylpyrrolidone, mixed and homogenized; - sodium carboxymethyl cellulose; mix and homogenize. A thickener, hydrated silica, is charged in portions. Mix and homogenize.

Then, the following is loaded into the reactor: - a composition of essential oils and extracts of medicinal plants; fragrance - peppermint essential oil; - aqueous solutions of the dye CI 42090 and CI 19140. Stir and homogenize.

Next, an aqueous solution of sodium lauryl sulfate is charged to the reactor. Mix and homogenize. The mass is evacuated and cooled to a temperature of 30 ± 2 ° C. The prepared mass of toothpaste is checked for compliance with organoleptic and physico-chemical indicators: appearance, color, smell, taste, pH. If the indicators correspond to the norm, the toothpaste is packaged.

Toothpaste is a homogeneous pasty mass of light green color with a fresh, pleasant smell with notes of mint and eucalyptus and a pleasant taste characteristic of this appellation. Example 6. Toothpaste

Sorbitol 20,000

Sodium Carboxymethyl Cellulose 2,500

Polyvinylpyrrolidone 0.500

Sodium benzoate 0.750

Disodium EDTA 0.150

Hydrated silica 3,000

Eucalyptus Essential Oil 0.350

Methyl Salicylate 0.200

Anethol 0.050

Sweet Orange Essential Oil .00

Peppermint essential oil 1,500

Menthol 0.200

Aloe Leaf Extract 4,000

Clove essential oil .500

Oak Bark Extract 2,000

Calamus Rhizome Extract 1,750

Chamomile Flower Extract 2,000

Rowan Fruit Extract 1,500

Bearberry leaf extract 1,250

Sea buckthorn fruit extract 1,500

Polysorbate 80 1,800

Sodium Lauryl Sulfate 2,000

Sodium saccharinate 0.250

Calcium Chloride 1,000

Magnesium Chloride 0.050

Potassium chloride .500

Sodium Chloride 0.100

Calcium Glycerophosphate 1,000

Sodium Fluoride 0.050

Dye CI 42090 0.050

Dye CI 19140 0,100

Dye CI 77891 1,000

Water 48,200

100,000

Toothpaste is prepared in the same way as described in example 5. Toothpaste is a homogeneous pasty mass of light green color with a fresh, pleasant smell with notes of mint and eucalyptus and a pleasant taste characteristic of this appellation.

Claims

CLAIM

1. An oral cosmetic product containing a remineralizing complex in the form of calcium, magnesium, sodium, and potassium salts, a structure-forming base, and water, which can be treated by the addition of an antimicrobial complex, plant extracts, menthol, ethyl alcohol and sodium benzoate as a preservative.

2. An oral cosmetic product according to claim 1, which is distinguished by the fact that, as a remineralizing complex, it contains a complex of calcium, magnesium, potassium and sodium ions contained in sodium fluoride and / or calcium chloride, calcium glycerophosphate, magnesium chloride, potassium chloride, sodium chloride, and disodium EDTA.

3. Oral care cosmetic according to claim 1 and claim 2 of the formula, characterized in that it contains methyl salicylate, anethole, essential oils of eucalyptus, peppermint, sweet orange and essential as an antimicrobial complex clove oil and / or clove extract.

4. Oral care cosmetic product according to any one of claims 1 to 3, claims that plant extracts of sage leaves and / or aloe leaves are introduced as plant extracts , oak bark, rowan fruits, calamus rhizomes, bearberry leaves, chamomile flowers and sea buckthorn fruits.

5. An oral cosmetic product according to any one of claims 1 - 4, wherein, as the structure-forming base, sorbitol and / or sodium carboxymethyl cellulose and / or hydrated dioxide are introduced silicon and / or polyvinylpyrrolidone.

6. Cosmetic product for caring for the oral cavity according to any one of claim 1 to claim 5, characterized in that dyes and flavoring are additionally introduced.

7. An oral cosmetic product according to any one of claims 1 to 6, characterized in that it additionally contains sodium lauryl sulfate and / or polysorbate 80.

8. A cosmetic product for caring for the oral cavity according to any one of p. 1 - p. 7 of the formula, which can be used in that it contains these components in the following ratios, wt%

Menthol 0.05-0.20

Eucalyptus essential oil 0.1-0.5

Methyl salicylate 0.05-0.25

Anetol 0.01-0.05

Sweet Orange Essential Oil 0.01-0.25

Peppermint essential oil 0.01-1.50

Clove essential oil and / or extract

0.01-0.5

carnations

Sage and / or aloe leaf extract 1.0-5.0

Oak Bark Extract 0.5-2.0

Calamus Rhizome Extract 0.5-2.0

Chamomile Flower Extract 0.5-2.0

Rowan fruit extract 0.5-2.0

Bearberry leaf extract 0.1-2.0

Sea buckthorn fruit extract 0.1-2.0

Sodium saccharinate 0.01-0.25

Disodium salt of EDTA 0.10-0.20

Calcium Chloride 0.1-1.0

Magnesium chloride 0.05-1.0

Sodium fluoride and / or potassium chloride 0.001 -0.55

Sodium chloride 0.1-0.9 Calcium Glycerophosphate 0.1-1.0

Preservative 0.10 -30.0

Dye 0.001-1.15

Sorbitol and / or Sodium Carboxymethyl

cellulose and / or polyvinylpyrrolidone

0.10-30.00 and / or hydrated silicon dioxide

Sodium lauryl sulfate and / or polysorbate 80 0.50 - 4.00

Water Else