RU2119328C1 - Toothpaste - Google Patents

Abstract

FIELD: stomatology, in particular, hygiene of oral cavity. SUBSTANCE: toothpaste has the following ratio of components, mas.%: chalk, 20-40; sodium carboxymethylcellulose, 1-3; glycerin or sorbitol, 14-40; sodium laurylsulphate, 0.5-2.0; antiseptic-conserving agent, 0.05-0.5; vitamin E (25-% oil solution), 0.8-1.0; flavor, 0.5-1.5; dicalcite phosphate, 2.0-2.2; perfume oil, 0.8- 1.0; sodium saccharate, 0.015-0.02; water, the balance. EFFECT: prophylaxis of formation of soft and hard dental depositions; reduced inflammatory diseases; reduced stomatorrhagia; improved functional condition of oral cavity and tongue.

Description

 The invention relates to dentistry, in particular to oral hygiene products, and can be used to prevent the formation of soft and hard dental deposits, reduce inflammatory diseases (gums, periodontal), reduce bleeding gums, and also to stimulate salivation by acting on salivary membranes glands in order to improve the functional state of the organs of the oral cavity and tongue.

 Toothpastes are conditionally divided into hygienic and therapeutic. Hygienic toothpastes are designed primarily for mechanical cleaning of teeth. They consist of an abrasive filler, a plasticizer, foaming surfactants.

 In addition to the specified ingredients, medicinal and preventive toothpastes include biologically active substances (BAS), such as vitamins, enzymes, extracts and extracts of medicinal plants, microelements, salts, and others. Medical and preventive pastes are used in the complex treatment of caries, diseases of periodontal tissues, hyperesthesia of enamel and dentin, stomatitis.

 Calcium and fluoride-containing toothpastes Arbat, Zhemchug, Moskvichka, Leningradskaya, Yubileynaya, Severyanka, Nevskaya, Fluorodent, Zodiac, Molodezhnaya have anti-carious effects Sage "," Binaka ". The complex of salts contains pastes "Cheburashka" and "Remodent". Of the imported pastes in our country, Signal, Zacalut, Pepsodent, Chlorodont, Fluirfonte, Fluorodent, Dentoluxus, Polana, Copadent, etc. are known.

 When bleeding gums, toothpastes are shown that stop it, improve metabolic processes, contribute to the elimination of the inflammatory process in the gums, have a general tonic effect, eliminate bad breath. Such pastes include Sputnik, Lesnaya, Osobaya, Emerald, Chlorophyll, Binaka, Chamomile, Novaya, Ira, Boydont. These pastes are applied to the gum for five minutes before brushing so that the biologically active substances are absorbed into it. Toothbrushing with these pastes is combined with gum massage.

 With the rapid formation of plaque, toothpastes containing enzymes (pancreatin), magnesium salts, and others are shown. These include Special, White-Pink, Enchantress, Balm, Olympiad, Mary, Pomorin "," Neopomorin "," Fructopomorin ".

 With fungal stomatitis, toothpastes are used, which include boroglycide: Boroglycerin, Berry. Toothpastes “South”, “Sage”, “Bee”, “Black Sea” simulate the reparative process in periodontal tissues, and “Phosphatization” has anti-inflammatory and anti-carious effects.

For ulcerative and necrotic processes, pastes are recommended to be used in the following sequence: first (to cleanse the ulcer surface of Belorozova, then the antibacterial Propolis and Prima containing vitamin B ₃ and calcium pantothenate.

 Known therapeutic toothpaste according to the application N 92011667/14 (12.28.92), A 61 K 7/16, which is called "Bioston". The therapeutic and prophylactic paste is created on the basis of a natural coniferous complex containing preparations of chlorophyll, carotene, vitamins E and D, stearins, phytol and other biologically active substances. Along with this, it contains drugs that promote the dissolution of soft dental deposits, and a preservative that stabilizes the composition.

 Known paste for the treatment of periodontal disease according to the patent of the Russian Federation N 2026062 (10.01.95), A 61 K 6/00, 9/08, containing antibacterial substances, oily 30% solution of vitamin E, chymotrypsin, dibunol, zinc oxide, as antibacterial substances - dioxidine, zinc sulfate and cobalt sulfate in the following ratio of components, wt.%: dioxidine - 0.05-0.1; zinc sulfate - 0.11-0.44; cobalt sulfuric acid - 0.12-0.48; dibunol - 0.05-0.1; chymotrypsin - 0.005-0.01; zinc oxide - 45.0-50.0; vitamin E - the rest.

 Known toothpaste according to A.S. USSR N 1342502 (12.24.84), A 61 K 7/16, containing the following composition of components, wt.%: Chalk - 30 - 45, sodium carboxymethyl cellulose - 1-2; glycerin - 18-25; carbostimulin - 0.5-2.0; perfume oil - 0.5-1.0; sodium lauryl sulfate - 1.0-2.5; saccharin - 0.01-0.05; antiseptic - 0.05-0.5; perfume - 0.5-2.0; water is the rest.

 Known toothpaste according to A.S. USSR N 950387 (05.23.79), A 61 K 7/16, containing the following composition of components, wt.%: Chalk - 35-40; Aerosil - 4-6; sodium carboxymethyl cellulose - 0.7-1.0; glycerin - 18-25; xylitol - 2-4; vitamin A - 0.4-0.8; vitamin E - 0.4-0.8; sodium lauryl sulfate - 1-2; sodium benzoate - 0.3-0.7; perfume - 0.8-1.3; water - the rest (prototype).

 An object of the invention is to increase the preventive, anti-inflammatory properties of the paste due to the effect on the membrane structure of the salivary glands and an increase in the amount of saliva. Developed at the Department of Dentistry of the Ural Medical Academy together with the Yekaterinburg Perfume and Cosmetic Factory, toothpaste contains components in the following ratio, wt.%: Chalk - 20-40; glycerin or sorbitol - 14-40; dicalcite phosphate - 2.0-2.2; sodium carboxymethyl cellulose - 1-3; antiseptic preservative - 0.05-0.5; sodium lauryl sulfate - 0.5-2.0; sodium sugar - 0.015-0.02; Vitamin E - 0.8-1.0; perfume - 0.5-1.5; water is the rest.

 Toothpaste is prepared as follows. Half the amount of water required in the formulation is loaded into the container. With the stirrer switched on, sodium carboxymethyl cellulose was poured over 15 minutes, stirred for 2.5 hours, then the remaining water was added. After this, stirred for another 3.5 hours. The resulting homogeneous mass was kept at room temperature for one day. First, glycerol (or sorbitol), chalk are added to the prepared solution of sodium carboxymethyl cellulose for 20-30 minutes, and then dicalcite phosphate, sodium lauryl sulfate, antiseptic preservative (e.g. sodium benzoate), perfume, sodium sugar, perfume oil are added to the paste, 25% - oily solution of vitamin E with constant stirring over the next 20-30 minutes. To make the paste homogeneous, plastic, it is passed through a colloid mill, a dispersant, and then packaged. The introduction of dicalcite phosphate and sodium sugar into the paste provides a carioprophylactic and anti-periodontal effect. Chalk (filler) is introduced into the paste at a rate of 20-40%, sodium carboxymethyl cellulose at a rate of 1-3%. This amount is due to the fact that with the introduction of chalk less than 20% with a simultaneous minimum injection of sodium carboxymethyl cellulose (1%), a paste of liquid consistency is obtained and, conversely, if chalk is more than 40% and sodium carboxymethyl cellulose more than 3%, the toothpaste thickens during storage.

 Glycerin in the amount of 14-40% gives the paste elasticity and protects it from drying out. Its introduction of less than 14% leads to a quick thickening of the paste, more than 40% dilutes it.

 To ensure optimal foaming and washing properties, sodium lauryl sulfate was introduced in an amount of 0.5-2.0%. An antiseptic preservative, introduced in an amount of 0.05-0.5%, gives the paste antimicrobial properties and protects the paste from bacterial contamination.

 The introduction of perfumes in the amount of 0.5-1.5%, perfume oil 0.8-1.0% is determined based on a study of the organoleptic properties of the paste.

 The introduction of vitamin E increases the therapeutic effect of the paste by activating the processes of maturation and mineralization of tooth enamel, increasing its resistance; increases the stability of hard tooth tissues and, through the mucous membrane of the oral cavity, promotes the synthesis of sulfated glycosaminoglycans of periodontal tissues, thereby improving reparative processes and the therapeutic effect in general; improves metabolic processes in periodontal tissues, increasing their resistance to adverse factors; acts on the membrane structures of the salivary glands, increasing the amount and quality of saliva, thereby reducing dry mouth and improves the functional state of the tongue.

 In addition, the proposed toothpaste has more pronounced antimicrobial properties. It exerts not only stronger inhibition of staphylococcus growth, but also inhibits the growth of the fungus.

 Toothpaste does not have a toxic effect and is completely harmless to the body.

Claims (1)

Toothpaste containing chalk, sodium carboxymethyl cellulose, glycerol or sorbitol, sodium lauryl sulfate, preservative preservative, vitamin E, perfume and water, characterized in that it additionally contains dicalcite phosphate, perfume oil and sodium sugar in the following ratio, wt.%:
Chalk - 20 - 40
Sodium carboxymethyl cellulose - 1 - 3
Glycerin or sorbitol - 14 - 40
Sodium lauryl sulfate - 0.5 - 2.0
Antiseptic preservative - 0.05 - 0.5
Vitamin E - 0.8 - 1.0
Fragrance - 0.5 - 1.5
Dicalcite Phosphate - 2.0 - 2.2
Perfume oil - 0.8 - 1.0
Sodium sugar - 0.015 - 0.02
Water - Rest