WO2020085473A1 - Procédé de vaporisation sélective pour composant répulsif anti insectes nuisibles - Google Patents

Procédé de vaporisation sélective pour composant répulsif anti insectes nuisibles Download PDF

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WO2020085473A1
WO2020085473A1 PCT/JP2019/041850 JP2019041850W WO2020085473A1 WO 2020085473 A1 WO2020085473 A1 WO 2020085473A1 JP 2019041850 W JP2019041850 W JP 2019041850W WO 2020085473 A1 WO2020085473 A1 WO 2020085473A1
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oil
solvent
evaporation
composition
plant essential
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PCT/JP2019/041850
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English (en)
Japanese (ja)
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鋭三郎 阿南
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アース製薬株式会社
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Priority to CN201980053324.2A priority Critical patent/CN112566498B/zh
Priority to JP2020552617A priority patent/JP7364312B2/ja
Publication of WO2020085473A1 publication Critical patent/WO2020085473A1/fr

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/18—Vapour or smoke emitting compositions with delayed or sustained release
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/04—Oxygen or sulfur attached to an aliphatic side-chain of a carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Definitions

  • the present invention relates to a method for selective evaporation of pest repellent components contained in plant essential oils.
  • Pest repellents For example, natural ingredients such as plant essential oils such as repellents against sanitary pests such as mosquitoes containing copaiba oil as an active ingredient (Patent Document 1) and mosquito repellents composed of components derived from lemongrass (Patent Document 2) are used as active ingredients. Pest repellents have been proposed. Many of these pest repellents derived from natural ingredients obtain repellent effects by applying an active ingredient to a protection target such as by directly spraying on human skin or clothes. It is difficult to obtain such an excellent repellent effect in a space such as a room by applying such a pest repellent derived from a natural component to a heating evaporation device equipped with an absorbent core, and there is still room for studying the means. It was
  • the present invention by using a heating evaporation device equipped with an absorbent core, it is possible to sufficiently diffuse the pest repellent component in the space such as indoors, a selective evaporation method of the pest repellent component contained in the plant essential oil Is intended to provide.
  • the present inventor as a result of repeated studies to solve the above problems, a composition for heating evaporation containing a plant essential oil and a specific solvent, by heat evaporation by a liquid absorption heating evaporation device, plant essential oil It has been found that the transpiration property of the pest repellent component contained in can be selectively improved, and the present invention has been completed.
  • the present invention specifically has the following matters.
  • Selective evaporation of the pest repellent component (B) contained in the plant essential oil characterized in that the composition for heating evaporation containing the plant essential oil and the following solvent (A) is heated and evaporated by a liquid absorption heating evaporation device.
  • Solvent (A) One selected from a solvent (a1) consisting of only an ester compound having a boiling point of 180 ° C. or higher and a solvent (a2) consisting of a mixture of hydrocarbon compounds having a boiling point range of 200 to 280 ° C. More solvent. 2.
  • the pest repellent component (B) is one or more selected from citronellol, geraniol, linalool, menthol, menthone and menthyl acetate.
  • the plant essential oil is one or more selected from citronella oil, lavender oil, peppermint oil, lemon eucalyptus oil and peppermint oil. Or 2.
  • Solvent (A) One selected from a solvent (a1) consisting of only an ester compound having a boiling point of 180 ° C. or higher and a solvent (a2) consisting of a mixture of hydrocarbon compounds having a boiling point range of 200 to 280 ° C. More solvent.
  • the selective evaporation method of the pest repellent component of the present invention is a composition for heating evaporation containing a plant essential oil and a specific solvent, by heat evaporation by a liquid absorption heating evaporation device, the insect repellent component contained in the plant essential oil. It is possible to suppress a decrease in the amount of transpiration caused by poor transpiration, thermal decomposition, and poor liquid absorption, and selectively improve the transpiration property. As a result, the pest repellent component contained in the plant essential oil can be sufficiently diffused throughout the space such as indoors, and an excellent pest repellent effect can be obtained.
  • the selective transpiration method of the pest repellent component of the present invention is a method characterized in that the composition for heat evaporation containing the solvent (A) is heat evaporated by a liquid absorption type heat evaporation device.
  • the solvent (A) of the present invention is a solvent (a1) consisting only of an ester compound having a boiling point of 180 ° C. or higher and a solvent (a2) consisting of a mixture of hydrocarbon compounds having a boiling point range of 200 to 280 ° C. )
  • One or more solvents selected from it is preferable that the solvent (A) of the present invention consists only of a solvent selected from the group consisting of the solvent (a1) and the solvent (a2).
  • the solvent (a1) of the present invention is a solvent consisting only of an ester compound having a boiling point of 180 ° C or higher.
  • the boiling point in this specification means the value measured under atmospheric pressure.
  • an ester compound having 12 to 30 carbon atoms is preferable.
  • Examples of the ester compound having 12 to 30 carbon atoms include alkyl ester of carboxylic acid having 12 to 30 carbon atoms, and specific examples thereof include isopropyl myristate, hexyl laurate, isopropyl palmitate and the like.
  • alkyl carboxylic acid alkyl ester diisopropyl adipate, dioctyl adipate, diisononyl adipate, diisodecyl adipate, etc., dicarboxylic acid dialkyl ester having 12 to 30 carbon atoms, triethyl acetyl citrate, tributyl acetyl citrate, etc. ⁇ 30 acetyl citrate trialkyl ester, 12-30 carbon citrate trialkyl ester such as triethyl citrate, dibutyl phthalate, diisononyl phthalate 12-30 carbon phthalate dialkyl ester Le, and the like.
  • ester compound More preferred examples of the ester compound include alkylcarboxylic acid alkylesters having 12 to 30 carbon atoms, dicarboxylic acid dialkylesters having 12 to 30 carbon atoms, and acetylcitric acid trialkylester having 12 to 30 carbon atoms.
  • alkyl carboxylic acid alkyl esters having 12 to 30 carbon atoms and dicarboxylic acid dialkyl esters having 12 to 30 carbon atoms and particularly preferred are dicarboxylic acid dialkyl esters having 12 to 30 carbon atoms.
  • dibutyl phthalate isopropyl myristate, diisopropyl adipate, dibutyl adipate, bis-2-ethylhexyl adipate, diisononyl adipate, diisodecyl adipate, triethyl acetylcitrate, Acetyl tributyl citrate and triethyl citrate are mentioned, and more preferable ones are isopropyl myristate (boiling point: 193 ° C./2.7 kPa), diisopropyl adipate (boiling point: 293 ° C.), dibutyl adipate (boiling point: 305 °C), bis2-ethylhexyl adipate (boiling point: 335 ° C.), diisononyl adipate (boiling point: 227
  • the lower limit of the boiling point of the solvent (a1) is preferably 200 ° C. or higher, more preferably 250 ° C. or higher, even more preferably 270 ° C. or higher, and particularly preferably 290 ° C. or higher.
  • the upper limit of the boiling point is preferably 500 ° C or lower, more preferably 450 ° C or lower, and further preferably 400 ° C or lower.
  • adipic acid diester is preferable, and dibutyl adipate is more preferable.
  • the solvent (a2) of the present invention is one or more solvents selected from the solvent (a2) consisting of a mixture of hydrocarbon compounds having a boiling point range of 200 to 280 ° C.
  • a solvent having a boiling point range of 200 to 300 ° C. and composed of a mixture of hydrocarbon compounds may be used, and among them, a mixture of naphthene hydrocarbon compounds is preferable.
  • naphthenic hydrocarbons, saturated hydrocarbons having a cyclic structure in the molecule are also called cyclo paraffinic hydrocarbons, means a group of compounds having the same molecular formula as the olefinic hydrocarbon "C n H 2n" .
  • the naphthene-based hydrocarbon compound is known to have an inherent boiling point and viscosity according to its molecular weight and structural formula, but a naphthene-based hydrocarbon that is generally commercially available and widely used is a naphthene-based hydrocarbon compound. It is a mixture that has a boiling point of approximately 160 ° C. or higher and is identified by its boiling range. The boiling point complies with "Petroleum products-Distillation test method-Atmospheric pressure distillation test method" specified in JIS K 2254 or "Standard test method for distillation of petroleum products and liquid fuel at atmospheric pressure" specified in ASTM D86. It means what was measured.
  • the solvent (a2) of the present invention is preferably a mixture of these naphthene hydrocarbon compounds, and specific examples thereof include Exxon D80 and Exxol D110 manufactured by ExxonMobil.
  • the selective transpiration method of the pest repellent component of the present invention is a method characterized in that the composition for heat evaporation containing plant essential oil is heat evaporated by a liquid absorption type heat evaporation device.
  • the plant essential oil of the present invention can be used without limitation as long as it has a pest repellent component.
  • Examples of the pest repellent component (B) of the present invention include citronellol, geraniol, linalool, menthol, menthone, menthyl acetate, 1,8-cineole, terpineol, dihydromyrcenol, borneol, nerol, ethyl linalool, thymol, eugenol. , Benzyl benzoate, cinnamyl formate, geranyl formate, limonene, carvone, pulegone, camphor, damascon, citral, neral, perilaldehyde, phenylethyl alcohol, diphenyl oxide and the like.
  • citronella oil for example, citronella oil, lavender oil, peppermint oil, jasmine oil, neroli oil, bergamot oil, orange oil, geranium oil, petitgrain oil, lemon oil, lemongrass oil.
  • Cinnamon oil, eucalyptus oil, lemon eucalyptus oil, thyme oil, peppermint oil and the like are known.
  • citronella oil, lavender oil, peppermint oil, lemon eucalyptus oil, and peppermint oil are preferable.
  • At least one pest repellent component (B) selected from Menthyl exhibits the effect of being selectively evaporated.
  • Citronella oil is an essential oil extracted from the leaves of Citronella grass, which is a grass of the grass family. Since Citronella grass is a plant closely related to lemongrass, it is a refreshing citrus with a similar aroma. Citronella oil contains various components in addition to citronellal, geraniol, citronellol and the like.
  • the "citronella oil" in the present invention is not only citronella oil extracted from the leaves of the above citronella grass, for example, citronellal obtained by synthesis, geraniol, citronellol as the main component, and other components as necessary. A composition containing the above is also included. Among these, naturally derived citronella oil is preferable.
  • Lavender oil is an essential oil extracted from lavender flowers.
  • the variety of lavender used as a raw material of lavender oil is not particularly limited, and examples thereof include genuine lavender, spike lavender, and French lavender.
  • Lavender oil contains various components in addition to linalyl acetate, linalool, and the like.
  • the type of lavender oil used as the raw material for the method of the present invention is not particularly limited, and two or more types of lavender oil of different types may be mixed and used.
  • “lavender oil” is not only a general lavender oil obtained from the above-mentioned lavender flowers, but is mainly composed of, for example, synthetically obtained linalyl acetate or linalool, and other Compositions containing the components are also included.
  • Mint oil and peppermint oil are components extracted from plants of the genus Mint. Such mint oil and peppermint oil differ in component composition depending on the plant species as the raw material, and for example, there are those containing menthol as the main component and those containing carvone as the main component. Examples of plants of the genus Mint include peppermint such as Atlantic peppermint and Japanese peppermint, spearmint such as Dutch peppermint, and applemint such as malva peppermint.
  • Peppermint oil and peppermint oil derived from Japanese peppermint contain menthol as the main component.
  • Menthol oil contains other components such as menthol, menthone, and menthyl acetate, and peppermint oil contains other components such as menthone, cineole, and menthyl esters. Is included.
  • mint oil derived from spearmint contains carvone as a main component and other components such as limonene and cineol.
  • mint oils derived from spearmint contains carvone as a main component and other components such as limonene and cineol.
  • mint oil is not only a general peppermint oil obtained from the above-mentioned Mint plant, but for example, menthol, mentone obtained by synthesis, menthyl acetate as a main component, if necessary, Compositions containing other components are also included.
  • naturally derived peppermint oil obtained from a plant of the genus Mentha is preferable.
  • Lemon eucalyptus oil is a component extracted from Eucalyptus citriodora and is called lemon eucalyptus oil because it has a scent similar to lemon.
  • Eucalyptus oil has 1,8-cineole as its main component, while lemon eucalyptus oil has citronellal as its main component.
  • Naturally-derived plant essential oils such as citronella oil, lavender oil and peppermint oil are obtained by subjecting a plant or its part as a raw material to steam distillation or squeezing.
  • the composition for heat-transpiration of the present invention contains a plant essential oil and a solvent (A), and the amount of the plant essential oil to be mixed in the composition for heat-transpiration is in the range of 0.1% by weight to 90% by weight. Is preferable, the range of 1% by weight or more and 50% by weight or less is more preferable, and the range of 3% by weight or more and 20% by weight or less is further preferable.
  • the amount of the solvent (A) blended in the composition for heat evaporation is preferably 10% by weight or more and 95.5% by weight or less, more preferably 50% by weight or more and 95% by weight or less, and 70% by weight or less.
  • the range of 90% by weight or more is more preferable.
  • the composition for heat evaporation of the present invention may contain other optional components as long as the effects of the present invention are exhibited.
  • Other optional components include, for example, insecticides other than plant essential oils, insect repellents, pest control components such as repellents, deodorants, fungicides, antioxidants, ultraviolet absorbers, stabilizers, pigments.
  • a preservative, a pH adjuster, an ultraviolet absorber, a fragrance, a bactericide, an antistatic agent, an antifoaming agent, a synergist, an inorganic powder, a surfactant, a solubilizing agent and the like can be used.
  • the content of these optional components in the composition for heat evaporation is preferably 0.01% by weight or more and 10% by weight or less, more preferably 0.1% by weight or more and 5% by weight or less.
  • insecticides include natural pyrethrins, pyrethrins, allethrins, phthalthrins, resmethrins, flamethrins, permethrins, phenothrins, cyphenothrins, pralethrins, bifenthrins, transfluthrins, metofluthrins, profluthrins, imiprothrins, empentorenes, etofenproxin, etofenproxin, and etofenprothrin.
  • Pyrethroid insecticides include carbamate insecticides such as propoxur and carbaryl; organophosphorus insecticides such as fenitrothion and DDVP; oxadiazole insecticides such as methoxadiazone; phenylpyrazole insecticides such as fipronil; imidacloprid and dinotefuran.
  • Neonicotinoid insecticides such as amidoflumet
  • pyrrole compounds such as chlorfenapyr
  • methoprene Insect juvenile hormone-like compounds such as hydroprene
  • Antijuvenile hormone-like compounds such as plecosene
  • Molting hormone-like compounds such as ecdysone
  • Chitin synthesis inhibitors such as chlorfluazuron, diflubenzuron, hexaflumuron, buprofezin
  • Isobol Examples thereof include one or two or more of nylthiocyanoacetate, isobornylthiocyanoethyl ether, quaternary ammonium salt, benzyl salicylate and the like.
  • Insect repellents and repellents include, for example, diet, di-n-butyl succinate, hydroxyanisole, rotenone, ethyl-butylacetylaminopropionate, icaridin (picaridine), 3- (Nn-butyl-N-).
  • acetyl) aminopropionic acid ethyl ester and the like can be mentioned.
  • the composition for heat evaporation of the present invention does not contain pest control components such as insecticides, insect repellents and repellents other than plant essential oils.
  • the present invention is characterized in that a composition for heat evaporation containing a plant essential oil and the following solvent (A) is heat evaporated by a liquid absorption type heat evaporation device.
  • a liquid absorption type heat evaporation device in the present invention, any liquid absorption type heat evaporation device utilizing various conventionally known liquid absorption cores can be used.
  • the composition for heat evaporation of the present invention is sucked up by a liquid absorbent core, and if it is a method of heating and evaporating by an arbitrary heating method, it is not particularly limited in shape, size, material, for example, electric There are two types of plug-type type that directly inserts the device body into the outlet with a heating method, and a stand-type type that has a cord on the device body.
  • the liquid absorption core of the liquid absorption type heat evaporation device is not particularly limited in material, diameter, length and shape as long as it can gradually absorb the composition for heat evaporation of the present invention. Examples thereof include felt, non-woven fabric, cotton, pulp, unglazed, and inorganic moldings.
  • a porous core of synthetic resin such as polyester or a core obtained by hardening a synthetic fiber bundle with resin can be used. Further, it may be a hollow liquid absorbent core such as a capillary tube.
  • the inorganic molded product porcelain porous, glass fiber, those obtained by fixing inorganic fibers such as asbestos with a binder such as gypsum and bentonite, kaolin, activated clay, talc, diatomaceous earth, clay, perlite, Mineral powders such as gypsum, bentonite, alumina, silica, alumina silica, titanium, vitreous volcanic rock firing powder, vitreous volcanic ash firing powder, etc., alone or together with wood powder, charcoal powder, activated carbon, etc., for example, dextrin, starch Examples include those solidified with gum arabic, carboxymethyl cellulose, and the like.
  • a heating element that generates heat when energized for example, a PTC heater (positive temperature coefficient thermistor), a ceramic heater, or the like is generally used, but the heating method is not limited to this, and for example, an air oxidation heating material,
  • the heating may be performed by any known heating element such as a heating material utilizing a platinum catalyst or the like.
  • the heating temperature is determined in consideration of the evaporation amount of the composition for heating evaporation per unit time.
  • the surface temperature of the heating heater alone in the liquid absorption heating evaporation device is about 70 ° C to 200 ° C, preferably about 85 ° C to 160 ° C, more preferably about 100 to 150 ° C, most preferably about 110 to 140 ° C. It is recommended to set it in the range. This temperature is set such that the composition for heat evaporation in the present invention evaporates at a temperature of about 60 ° C to 185 ° C, preferably about 75 ° C to 135 ° C, more preferably about 80 to 125 ° C, and most preferably about 85 to 115. Equivalent to about °C.
  • the liquid absorption type heating evaporation device having the liquid absorption core as described above, from the liquid medicine container for containing the composition for heating evaporation, while absorbing the composition for heating evaporation into the liquid absorption core, heating method (for example, the pest repellent component (B) contained in the plant essential oil is selectively evaporated by heating the upper side surface of the absorbent core with a heating element).
  • heating method for example, the pest repellent component (B) contained in the plant essential oil is selectively evaporated by heating the upper side surface of the absorbent core with a heating element.
  • a known liquid absorption heating evaporation device can be used in the present invention, such as the device described in JP-A-63-240738.
  • the composition for liquid absorption heating evaporation for selective evaporation of the present invention contains a vegetable essential oil selected from citronella oil, lavender oil, peppermint oil, lemon eucalyptus oil and peppermint oil, and the solvent (A). Yes, use by selectively evaporating one or more pest repellent components (B) selected from citronellol, geraniol, linalool, menthol, menthol and menthyl acetate by heating and evaporating using a liquid absorption heating evaporation device Is used for.
  • Example 1-1 20 parts by weight of citronella oil and 80 parts by weight of dibutyl adipate (boiling point: 305 ° C.) were mixed to prepare a composition for heat evaporation of Example 1-1.
  • Example 1-2 20 parts by weight of citronella oil and 80 parts by weight of "Exol D80” (boiling range: 200 to 250 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Example 1-2.
  • Example 1-3 20 parts by weight of citronella oil and 80 parts by weight of “Exol D110” (boiling range: 237 to 277 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Example 1-3.
  • Example 2-1 20 parts by weight of lavender oil and 80 parts by weight of dibutyl adipate (boiling point: 305 ° C.) were mixed to prepare a composition for heat evaporation of Example 2-1.
  • Example 2-2 20 parts by weight of lavender oil and 80 parts by weight of “Exsol D80” (boiling point range: 200 to 250 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Example 2-2.
  • Example 2-3 20 parts by weight of lavender oil and 80 parts by weight of “Exsol D110” (boiling range: 237 to 277 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Example 2-3.
  • Example 3-1 20 parts by weight of peppermint oil and 80 parts by weight of dibutyl adipate (boiling point: 305 ° C.) were mixed to prepare a composition for heat evaporation of Example 3-1.
  • Example 3-2 20 parts by weight of peppermint oil and 80 parts by weight of “Exol D80” (boiling point range: 200 to 250 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Example 3-2.
  • Example 3-3 20 parts by weight of peppermint oil and 80 parts by weight of “Exol D110” (boiling point range: 237 to 277 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Example 3-3.
  • Comparative Example 1 20 parts by weight of citronella oil and 80 parts by weight of “Exol D130” (boiling range: 275 to 318 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Comparative Example 1.
  • Comparative example 2 20 parts by weight of lavender oil and 80 parts by weight of “Exsol D130” (boiling range: 275 to 318 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Comparative Example 2.
  • Comparative Example 3 20 parts by weight of peppermint oil and 80 parts by weight of "Exsol D130” (boiling range: 275 to 318 ° C) manufactured by ExxonMobil were mixed to prepare a composition for heat evaporation of Comparative Example 3.
  • Citronella oil contains 14% by weight of citronellol and 19% by weight of geraniol, based on the total weight.
  • Lavender oil contains 25% by weight of linalool, based on the total weight.
  • Mint oil contains 39% by weight of menthol, 45% by weight of menthone and 4% by weight of menthyl acetate, based on the total weight.
  • Evaporation rate (%) Evaporation amount of each pest repellent component / (Evaporation amount of a composition for heat evaporation x blending rate of each plant essential oil x content rate of each pest repellent component in each plant essential oil) x 100 The transpiration rate of each pest repellent component in the test sample is shown in Tables 1 to 3.
  • compositions for heat evaporation of Examples 1-1, 1-2, and 1-3 used in the method for selective evaporation of pest repellent components of the present invention show that the insect repellent contained in citronella oil is repelled. It was confirmed that the components citronellol and geraniol were selectively evaporated.
  • the compositions for heat evaporation of Examples 2-1, 2-2 and 2-3 used in the method for selectively vaporizing pest repellent components of the present invention contain linalool, which is a pest repellent component contained in lavender oil.
  • the composition for heat evaporation of Examples 3-1, 3-2, and 3-3, which is used for the method for selectively evaporating pest repellent components of the present invention that selectively evaporates, is contained in peppermint oil. It was confirmed that menthol, menthone, and menthyl acetate, which are pest repellent components, were selectively evaporated. Specifically, the composition for heat evaporation containing the solvent (a1) (Examples 1-1, 2-1, 3-1) and the composition for heat evaporation containing the solvent (a2) (Example 1-2, 2-2, 3-2, 1-3, 2-3, 3-3), the selective transpiration rate of the pest repellent component contained in plant essential oil was 74% at the minimum and 95% at the maximum.
  • the evaporation rate of the pest repellent component contained in the plant essential oil is about 23 to 58%. , It became clear that selective transpiration was not achieved.
  • Example box 1A unprocessed sample box 1B
  • transparent tubular attracting portions 2A and 2B connected to each, and further to each attracting portion. It is equipped with a transparent mosquito box 3.
  • a check valve 4 (funnel shape) that prevents mosquitoes that have entered the attracting parts from the mosquito containing box 3 from returning to the mosquito containing box 3 at the connection part between the mosquito containing box 3 and the attracting parts 2A and 2B. Is provided.
  • Clean air is generated in the olfactometer 10 from the sample boxes 1A, 1B side toward the mosquito housing box 3 at a flow rate of 0.3 m / s (the air flow generation part is omitted in the drawing).
  • 25 Aedes albopictus ( ⁇ ) as test insects were put in the mosquito containing box 3, and the heat evaporation of the above-mentioned Example 1-2 or Comparative Example 1 was conducted as a test sample in the sample box 1A.
  • the composition was evaporated for 30 seconds (about 1 mg).
  • the composition for heat evaporation is promptly removed, the hands are put on the sample box 1A and the untreated sample box 1B up to the wrist, and after 5 minutes, the number of mosquitoes invading the attracting part 2A and the attracting part 2B is measured. I went.
  • Example 1-2 used in the method for selectively vaporizing pest repellent components of the present invention selectively selects citronellol and geraniol, which are the pest repellent components contained in citronella oil.
  • citronellol and geraniol are the pest repellent components contained in citronella oil.
  • the composition for heat evaporation of Comparative Example 1 containing the same citronella oil as in Example 1-2 but not containing the solvent (A) of the present invention is a pest repellent component. It was confirmed that citronellol and geraniol could not be evaporated selectively, and that they did not exert sufficient pest repellent effect.
  • Reference Test Specimen 2 p-menthane-3,8-diol 1 part by weight, isopropanol 10 parts by weight, hydrocarbon solvent (mixture having 14 to 16 carbon atoms, boiling range: 245 to 285 ° C.) 71.2
  • a reference test sample 2 was prepared by mixing 1 part by weight and 17.8 parts by weight of a hydrocarbon solvent (mixture having 16 to 18 carbon atoms, boiling range: 270 to 310 ° C.).
  • Reference Test Specimen 3 5 parts by weight of citronella oil, 10 parts by weight of isopropanol, 68.0 parts by weight of hydrocarbon solvent (mixture having 14 to 16 carbon atoms, boiling range: 245 to 285 ° C.) and hydrocarbon solvent (A reference test sample 3 was prepared by mixing 17.0 parts by weight of a mixture having 16 to 18 carbon atoms and a boiling range of 270 to 310 ° C.
  • the repellent effect confirmation test is carried out in a test section having a ceiling, a floor and four walls (floor area: about 50 m 2 , height: about 3.5 m). , Floor, 4 walls (floor area: about 10 m 2 , height: about 2.4 m).
  • Untreated test The test insects (about 150 Aedes aegypti ⁇ ) were released in the test zone and acclimated for 1 hour. Next, one subject was placed in the treated section, a gap was opened in the wall of the treated section (width: about 10 cm, height: 180 cm), and the untreated test was started so that the test section was communicated.
  • invasion number p1 the number of test insects invading the treated area
  • time t1 the time when the "invasion number p1" was 30 or more
  • time t1 was measured.
  • the time (t1) was determined by observing every 5 minutes after 2 minutes, 5 minutes, 7 minutes, 10 minutes, and 10 minutes.
  • Iii Heat transpiration test
  • the test subject in the treatment area was allowed to leave the room, the window provided on the wall of the treatment area was closed, and then the test insects with the above-mentioned "invasion number p1" were added to the test area for 1 hour.
  • the liquid absorption heating evaporation device (heating surface temperature: about 127 ° C., composition evaporation temperature: about 108 ° C.) in which any of the above reference test samples 1 to 3 is set in the treatment area is operated for 1 hour, Any of the reference test samples 1 to 3 was evaporated.
  • One test subject was placed again in the treatment zone, and a heat evaporation treatment test was started by opening a gap in the wall of the treatment zone (width: about 10 cm, height: 180 cm) so as to communicate with the test zone. From the start of the heat transpiration treatment test to the passage of "time t1", the number of test insects invading the treatment area (hereinafter referred to as "invasion number p2”) was measured.
  • the air evaporation treatment test was started so as to communicate with the test area.
  • the number of test insects invading the treatment area (hereinafter referred to as "invasion number p3") was measured from the start of the air evaporation treatment test to "time t1".
  • the heat evaporation repellent rate (%) or the wind evaporation repellent rate (%) was calculated by the following formula.
  • the heat transpiration test using the reference test samples 1 and 2 and the wind transpiration test using the reference test sample 1 were repeated three times, respectively.
  • the average repellency (%) of each is shown in Table 5 below.
  • Heat evaporation evasion rate (%) (number of intrusions p1-number of intrusions p2) / number of intrusions p1 x 100
  • Wind evaporation repellent rate (%) (number of intrusions p1-number of intrusions p3) / number of intrusions p1 x 100
  • the reference test sample 1 containing citronella oil and p-menthane-3,8-diol was p-menthane-3,8-diol when it was evaporated using a liquid absorption heating evaporation device. It was confirmed that a repellent effect of about 3 times was obtained as compared with the reference test sample 2 containing only citronella oil and the reference test sample 3 containing only citronella oil. Furthermore, when the reference test sample 1 having the same composition is evaporated using a liquid absorption heating evaporation device and an evaporation device using wind, the heating evaporation may have a repelling effect of about 3 times that of wind evaporation. confirmed.
  • This excellent pest repellent effect is a synergistic effect more than the additive effect obtained by using the plant essential oil such as citronella oil in combination with p-menthane-3,8-diol.
  • a plant essential oil such as citronella oil and p-menthane-3,8-diol are used together to evaporate using a liquid absorption heating evaporation device, the plant essential oil such as citronella oil is evaporated alone. It was also confirmed by an evaluation test (9 specialized panelists) that a more highly fragrant scent can be obtained as compared with.
  • a pest repellent composition for a liquid absorption heating evaporation device comprising a plant essential oil and p-menthane-3,8-diol.
  • a pest repellent composition for a liquid absorption heat evaporation device which comprises one or more plant essential oils selected from citronella oil, lavender oil, mint oil, eucalyptus oil and peppermint oil, and p-menthane-3,8-diol .
  • a pest repellent method comprising heating and evaporating a pest repellent composition containing a plant essential oil and p-menthane-3,8-diol with a liquid absorption type heat evaporation device.
  • Selective transpiration method of the pest repellent component of the present invention is a composition for heating transpiration in which a plant essential oil and a specific solvent are combined, by transpiration by heating with a liquid absorption heating transpiration device, the pest repellent component contained in the plant essential oil. It is possible to suppress the decrease in the amount of transpiration caused by poor transpiration, thermal decomposition and poor liquid absorption, and selectively improve the transpiration property. This makes it possible to spread the necessary amount of pest repellent components contained in plant essential oil to the entire space such as indoors using a liquid absorption heating evaporation device, and achieve an extremely excellent pest repellent effect. It can be done.

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention aborde le problème consistant à fournir un procédé de vaporisation sélective pour un composant répulsif anti insectes nuisibles contenu dans une huile essentielle de plante, le composant répulsif anti insectes nuisibles pouvant être suffisamment diffusé dans un espace tel qu'un espace intérieur à l'aide d'un dispositif de vaporisation thermique équipé d'une mèche d'aspiration de liquide. La solution de l'invention porte sur un procédé caractérisé en ce qu'il comprend la vaporisation d'une composition pour pulvérisation thermique qui contient une huile essentielle de plante et un solvant (A), et le chauffage à l'aide d'un dispositif de vaporisation thermique de type aspiration de liquide pour ainsi vaporiser de manière sélective un composant répulsif anti insectes nuisibles (B) contenu dans l'huile essentielle de plante. Solvant (A) : un ou plusieurs types de solvants choisis parmi un solvant (a1) qui comprend exclusivement un composé d'ester ayant un point d'ébullition de 180 °C ou plus, et un solvant (a2) qui comprend un mélange de composés d'hydrocarbures ayant une plage de points d'ébullition entre 200 et 280 °C.
PCT/JP2019/041850 2018-10-26 2019-10-25 Procédé de vaporisation sélective pour composant répulsif anti insectes nuisibles WO2020085473A1 (fr)

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CN113367163A (zh) * 2021-05-28 2021-09-10 天津科技大学 天然驱虫灭菌香及其制备方法
EP4079156A1 (fr) * 2021-04-20 2022-10-26 Reckitt & Colman (Overseas) Hygiene Home Limited Composition de lutte contre les insectes
WO2022223967A1 (fr) * 2021-04-20 2022-10-27 Reckitt & Colman (Overseas) Hygiene Home Limited Composition de lutte contre les insectes
US11832618B2 (en) 2021-01-06 2023-12-05 S. C. Johnson & Son, Inc. Spatial insect repellent compositions

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JP2018008947A (ja) * 2016-06-30 2018-01-18 アース製薬株式会社 ゴキブリ用忌避剤の塗布方法
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JP2002173407A (ja) * 2000-12-05 2002-06-21 Fumakilla Ltd 飛翔昆虫忌避剤
JP2003164249A (ja) * 2001-11-30 2003-06-10 Matsushita Electric Ind Co Ltd 衛生害虫忌避装置
JP2018008947A (ja) * 2016-06-30 2018-01-18 アース製薬株式会社 ゴキブリ用忌避剤の塗布方法
JP2018104540A (ja) * 2016-12-26 2018-07-05 株式会社イノアックコーポレーション 蚊忌避性ポリウレタンフォーム

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11832618B2 (en) 2021-01-06 2023-12-05 S. C. Johnson & Son, Inc. Spatial insect repellent compositions
EP4079156A1 (fr) * 2021-04-20 2022-10-26 Reckitt & Colman (Overseas) Hygiene Home Limited Composition de lutte contre les insectes
WO2022223967A1 (fr) * 2021-04-20 2022-10-27 Reckitt & Colman (Overseas) Hygiene Home Limited Composition de lutte contre les insectes
CN113367163A (zh) * 2021-05-28 2021-09-10 天津科技大学 天然驱虫灭菌香及其制备方法

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