WO2020043334A1 - Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel - Google Patents

Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel Download PDF

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Publication number
WO2020043334A1
WO2020043334A1 PCT/EP2019/063515 EP2019063515W WO2020043334A1 WO 2020043334 A1 WO2020043334 A1 WO 2020043334A1 EP 2019063515 W EP2019063515 W EP 2019063515W WO 2020043334 A1 WO2020043334 A1 WO 2020043334A1
Authority
WO
WIPO (PCT)
Prior art keywords
section
wall
storage container
drug
separating device
Prior art date
Application number
PCT/EP2019/063515
Other languages
German (de)
English (en)
French (fr)
Inventor
Dietmar Gross
Original Assignee
Becton Dickinson Rowa Germany Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Rowa Germany Gmbh filed Critical Becton Dickinson Rowa Germany Gmbh
Priority to KR1020217005501A priority Critical patent/KR102694096B1/ko
Priority to JP2021510868A priority patent/JP7304938B2/ja
Priority to CN201980056289.XA priority patent/CN112638346B/zh
Publication of WO2020043334A1 publication Critical patent/WO2020043334A1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0076Medicament distribution means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B39/00Nozzles, funnels or guides for introducing articles or materials into containers or wrappers
    • B65B39/007Guides or funnels for introducing articles into containers or wrappers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/02Enclosing successive articles, or quantities of material between opposed webs
    • B65B9/04Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
    • B65B9/045Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material for single articles, e.g. tablets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/04Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F11/00Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/005Special arrangements for insuring that only one single article may be dispensed at a time
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F11/00Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/02Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines
    • G07F11/44Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which magazines the articles are stored in bulk
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F17/00Coin-freed apparatus for hiring articles; Coin-freed facilities or services
    • G07F17/0092Coin-freed apparatus for hiring articles; Coin-freed facilities or services for assembling and dispensing of pharmaceutical articles

Definitions

  • Storage container for a storage and delivery station for
  • the present invention relates to a storage container for a supply and dispensing station for pharmaceuticals.
  • Modern blister machines as disclosed for example in WO 2013/034504 A1, comprise, depending on the stage of expansion, several hundred supply and delivery stations for medicines.
  • a plurality of medicament portions of a certain type of medicament are stored in each of these, and one or more medicament portions can be delivered on request.
  • the medicines stored in the supply and delivery stations are customized for the patient according to the times prescribed by the doctor
  • Appropriate supply and delivery stations for delivery of one or more individual drug portions controlled When a supply and delivery station is controlled, a single medicament portion is separated with a separating device and transferred to a guide device of the blister machine via a delivery opening. By means of the guide device, a dispensed portion of medication is dispensed, possibly under
  • Packing device supplied, which blistered single or multiple drug portions according to the medical requirements.
  • the separating device used for separating medicament portions is usually designed in the shape of a circular cylinder and is formed in a corresponding guide space of the storage container. On the scope of
  • Separating device is a plurality of
  • Drug channels are formed by protrusions which are formed in one piece with a main body of the separating device or can be detachably fastened to it.
  • Protrusions regularly have an arcuate lateral surface, which bear against an inner wall of the guide space in which the separating device is arranged (in the context of this application, the term “concern” does not mean that one surface is completely different from the other
  • a large number of medicament portions are arranged in the storage containers for the storage and delivery stations. When a medication portion is separated, the
  • Separating device rotates by a certain angle in order to feed a drug portion arranged in a drug channel to the delivery opening. Depending on the shape of the drug portions and the number of drug portions arranged in the storage container, these rub at the
  • the friction between the lateral surfaces of the projections and the wall increases, so that the separating device rotates with increasing drug dust deposition an increased force has to be applied. Due to the uneven force to be used to rotate the separating device, it is difficult to control the separating device precisely, so that incorrect dispensing can occur, which can lead to incorrect combinations of medicament portions.
  • Storage container according to claim 1 The storage container according to the invention for a storage and delivery station for
  • Drug portions include a receiving space for
  • Storage container is a separating device in the guide section of the housing with a central axis of rotation
  • the separating device comprises a central main section and a plurality of protrusions, each protrusion having two end sections and a central section and wherein a medicament channel is formed in each case between two end sections of adjacent projections.
  • the projections can be flatter than the main body of the guide device, which increases the supply of the drug portions
  • the outer lateral surface is regularly formed in a circular arc (based on a central axis of rotation) and the projections therefore form (if the drug channels are neglected) a type of hollow cylinder, the outer lateral surface of which rests on the inner wall of the guide section.
  • the projections are designed differently. It is according to the invention
  • the projections rest against the wall only with a small section (or are slightly spaced apart from it) and, if appropriate, are guided from or on the wall, it being provided according to the invention that it this section is an end section to which a drug channel connects.
  • this section is an end section to which a drug channel connects.
  • Wall / lateral surface of the middle section is greater than the distance wall / lateral surface of the end section.
  • central sections are arcuate, that the gap between the wall and the central section is designed like a segment of a hollow cylinder.
  • the middle section can also be like a kind with respect to the wall
  • a corresponding design of the protrusions has the result that pharmaceutical dust that arises during the separation can trickle down through the gap in the area of the central sections and is thus quickly led to the bottom surface, where, with the appropriate design of the bottom surface, it forms a
  • Receiving opening can be performed in the floor area.
  • Discharge opening is reduced in the storage container according to the invention.
  • End sections lie against the wall of the guide section, so it has a larger "radius" than that withdrawn
  • End sections allow a uniform and impact-free, low-friction rotation of the separating device in the guide section, which is regularly the case with three corresponding end sections (possibly also with two end sections if these are correspondingly wide).
  • End sections (viewed from the axis of rotation) are always arranged on the right or left of the projection. Depending on the direction of rotation, they are against the wall
  • the direction of rotation is regularly chosen so that the projecting end sections are "behind", that is, a drug channel follows an end section "Front”, thus follow a drug channel in the direction of rotation.
  • the separating device rotates briefly in such a way that the projecting end sections are located “at the front”. If the end sections are designed accordingly, drug dust adhering to the front edge of the end sections can then be removed from the wall. This then falls through the channels onto the floor surface.
  • both end sections of a projection are designed such that they abut the wall of the guide section.
  • Appropriate training improves the delivery of a drug portion into the drug channel. The cleaning described above is then no longer possible, a low-friction rotation of the separating device and one
  • the end sections of the projections resting on the wall of the guide section regardless of whether one or both projections are designed accordingly, are distributed symmetrically over the separating device.
  • Drug channels are offset by a central angle of 120 ° with respect to the axis of rotation.
  • the projections In order to prevent drug dust from adhering to the wall of the central section of the projections, it is provided in a preferred embodiment that the projections have a non-stick coating at least in the area of the central section on a lateral surface facing the wall. In order to prevent drug portions from remaining on the main body of the separating device and to support the supply of drug portions into the drug channels, it is provided in a preferred embodiment that the separating device has a conical surface with a plurality of depressions aligned with the drug channels.
  • Drug channels has recesses.
  • Figures 2a and 2b show top views of the first embodiment of the invention
  • FIGS 3a and 3b two sectional views of the first
  • FIGS. 4a and 4b also two sectional views
  • Figure 7 shows a detailed view of the separating device
  • Figure 8 shows a plan view of a separating device of a second embodiment
  • FIG. 9 shows a top view of a separating device of a third embodiment
  • Figure 10 shows a plan view of a separating device of a fourth embodiment.
  • Figures la and lb show two oblique views of one
  • the storage container 1 for a supply and dispensing station for pharmaceuticals.
  • Storage container 1 is part of the aforementioned storage and delivery station, the storage container
  • Dispensing station is arranged.
  • components can be arranged in the storage container or the delivery station.
  • FIG. 1b which shows the storage container from below, in the embodiment shown it does not comprise a motor, but rather only a coupling piece 31, via which a separating device (shown in more detail in the following figures) can be coupled to a motor in the delivery station is.
  • the storage container 1 comprises a housing 10 with a circular cylindrical section 11, to which a bottom section 12 is connected at the bottom.
  • the bottom section 12 is connected to the upper part of the housing via a handle 13 with which the storage container 1 can be removed from a corresponding delivery station.
  • a circular depression 22 is arranged around the coupling piece 31, which recess in the
  • FIGS. 2a and 2b show top views according to the first embodiment, with a cover 4 in both figures
  • a separating device 40 is arranged in a receiving space defined by the circular cylindrical section 11 of the housing.
  • This comprises a central main section 48 and a plurality of projections 42 arranged on the main section 48. These can be formed in one piece with the main section, but it is also possible that these are as releasable components can be fastened to the main section 48.
  • a medicament channel 41 is formed between each of two projections 42, via which medicament portions arranged in the storage container are conveyed to a (shown in FIG.
  • Dispensing channel 21 can be fed.
  • Separating device 40 comprises a conical surface 43 with four depressions 44, which are radial on the channels 41
  • Sections of a circular hollow cylinder are formed, but are withdrawn or flattened in the central section (relative to the axis of rotation), i. H. in these areas there is a gap between the protrusions and the inner one
  • Coupling device 30 is arranged, via which the
  • the coupling device itself can be made in one piece with the separating device
  • the separating device and the coupling device are usually releasably connected to one another, to quickly replace the separating device without
  • Figures 3a and 3b show an oblique view and a
  • FIG. 3a shows that the cut is made in such a way that it cuts through the separating device 40 between the drug channels 41.
  • a gap is provided between an inner wall 3 of the circular-cylindrical section 11 of the housing 10 and an outer circumferential surface 461 of a central section 46 of a projection 42, through which gap
  • Drug dust can trickle down onto the bottom surface 20 (the exact structure of the protrusions is described with reference to FIG. 1
  • FIGS. 3a and 3b and all subsequent figures the gap between the wall 3 and the outer lateral surface of a central section of a projection 42 is shown in an exaggerated manner to illustrate the invention.
  • the gap can of course be kept wider than with very small portions of the drug. It is essential that a corresponding gap is provided, over which
  • Drug dust can get past the separating device onto the floor surface.
  • the retention section prevents that, when a drug channel is aligned, from being arranged at the delivery opening above the drug channel
  • Portions of drug are delivered through the canal; only the drug portion contained in the channel when aligned is indicated.
  • Figures 4a and 4b also show two sectional views, the section being orthogonal to that of Figures 3a and 3b. You can also use FIGS. 4a and 4b
  • the bottom surface 20 is designed to slope down towards the center and comprises a depression 22, so that drug dust trickling down the gap can get into the depression 22 via the falling bottom surface.
  • the lower surface 49 of the separating device is also formed obliquely, so that between the bottom surface 20 and the
  • a separating device is formed through which drug dust can reach the recess 22.
  • FIGS. 5a - 5f show different views of the
  • the separating device comprises four channels 41, which are defined by four projections 42.
  • the main body 48 extends beyond the projections 42, i. H. in the field of
  • a circumferential depression is formed in the projections, which allows the drug portions to be fed into the channels 41
  • the separating device 40 comprises a conical upper surface 43 with four recesses 44 which are aligned with the drug channels. Recesses 44a are formed in the main body 48 and are aligned with the depressions 44 and the drug channels 41 Wells 44 support the delivery of drug portions into the drug channels 41.
  • the projections 42 each comprise two end sections 45 with jacket surfaces 451 and middle sections 46 with jacket surfaces 461
  • FIGS. 5e and 5f can already be seen that the projections are not designed in the form of a circular arc in relation to the central axis of rotation, but that the central sections
  • FIGS 6a and 6b show the arrangement of the
  • the separating device 40 in the circular-cylindrical guide space provided by the guide section 11 with the inner wall 3.
  • the separating device comprises four channels 41 and four projections 42.
  • the projections lie in the area the end portions 45 with
  • the radius RMA that is to say the distance from the lateral surface to the central axis of rotation DA
  • Figure 8 shows a top view of a second
  • Figure 9 shows a third embodiment of the
  • End sections 45 is larger than the radius RMI in the
  • Middle sections 46 In the embodiment shown, the middle section is related to the central axis of rotation
  • the middle section can also be formed by not being arch-shaped, but simply by forming a straight line between the end sections, which would lead to a gap with a different shape.
  • Figure 10 shows a fourth embodiment of the
  • the radius RMA is larger than the radius RMI of the middle section.
  • the “other” end section 47 is configured in the same way as that in the embodiment shown
  • the lateral surface 471 is in the area corresponding to the lateral surface 461 of the central section
  • the separating device When separating drug portions, the separating device is shown as shown
  • Embodiment regularly rotated clockwise, d. H. the projecting end sections run "in front" of one
  • End portions 45 are at the transition
  • the inventive design of the projections also ensures in all four embodiments that the friction between the separating device and the wall is reduced due to the reduced contact area wall / lateral surface compared to storage containers according to the prior art.

Landscapes

  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
PCT/EP2019/063515 2018-08-31 2019-05-24 Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel WO2020043334A1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020217005501A KR102694096B1 (ko) 2018-08-31 2019-05-24 약품용 보관 및 분배 스테이션을 위한 보관 용기
JP2021510868A JP7304938B2 (ja) 2018-08-31 2019-05-24 製薬の貯蔵及び分配ステーション用貯蔵容器
CN201980056289.XA CN112638346B (zh) 2018-08-31 2019-05-24 用于药品份的储存及分配站的储存容器

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18191874.9A EP3616675B1 (de) 2018-08-31 2018-08-31 Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel
EP18191874.9 2018-08-31

Publications (1)

Publication Number Publication Date
WO2020043334A1 true WO2020043334A1 (de) 2020-03-05

Family

ID=63452479

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2019/063515 WO2020043334A1 (de) 2018-08-31 2019-05-24 Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel

Country Status (5)

Country Link
EP (1) EP3616675B1 (zh)
JP (1) JP7304938B2 (zh)
KR (1) KR102694096B1 (zh)
CN (1) CN112638346B (zh)
WO (1) WO2020043334A1 (zh)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2227167A (en) * 1939-07-14 1940-12-31 Morton Salt Co Dispenser for tablets
WO2013034504A1 (en) 2011-09-09 2013-03-14 Carefusion Switzerland 317 Sàrl System and method for packaging dosed quantities of solid drug portions
EP2572995A1 (en) * 2010-05-17 2013-03-27 Yuyama Mfg. Co., Ltd. Tablet cassette

Family Cites Families (15)

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US2572995A (en) * 1946-03-26 1951-10-30 Allen S Dunbar Antenna
TW557277B (en) * 2001-09-30 2003-10-11 Yuyama Mfg Co Ltd Medicine packing apparatus
US7516829B2 (en) * 2002-04-25 2009-04-14 Kite International Co., Ltd. Vending machine of encapsulated article of commerce
GB0315509D0 (en) * 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
DE102006027521B4 (de) * 2006-06-10 2016-01-07 Edwin Kohl Anlage zur personenbezogenen Bestückung von Medikamentenspendern
EP2543603A4 (en) * 2010-03-01 2017-11-29 Yuyama Mfg. Co., Ltd. Powder removal device of medicine dispenser
EP2703299B1 (en) * 2012-08-31 2016-03-30 CareFusion Switzerland 317 Sarl A storage and dosing station for storage and dispensing dosed quantities of solid drug portions
KR101449717B1 (ko) * 2013-01-02 2014-10-15 주식회사 인포피아 약제 포장장치용 정제 카트리지
KR102083863B1 (ko) 2013-10-09 2020-03-03 가부시키가이샤 다카조노 테크놀로지 약제 충전 장치
GB2531996B (en) * 2014-10-20 2018-01-17 Trig1 Ltd Dispensing container with contents level indication
EP3199141A1 (de) * 2016-01-29 2017-08-02 Becton Dickinson Rowa Germany GmbH Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel
TWI724134B (zh) 2016-03-25 2021-04-11 日商湯山製作所有限公司 片劑盒用轉子以及片劑盒
US10255524B2 (en) * 2016-06-03 2019-04-09 Becton Dickinson Rowa Germany Gmbh Method for providing a singling device of a storage and dispensing container
EP3358538B1 (de) * 2017-02-03 2022-03-30 Becton Dickinson Rowa Germany GmbH Vorrats- und abgabestation für einen blisterautomaten
US10380824B2 (en) * 2017-02-03 2019-08-13 Becton Dickinson Rowa Germany Gmbh Storage and dispensing station for blister packaging machine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2227167A (en) * 1939-07-14 1940-12-31 Morton Salt Co Dispenser for tablets
EP2572995A1 (en) * 2010-05-17 2013-03-27 Yuyama Mfg. Co., Ltd. Tablet cassette
WO2013034504A1 (en) 2011-09-09 2013-03-14 Carefusion Switzerland 317 Sàrl System and method for packaging dosed quantities of solid drug portions

Also Published As

Publication number Publication date
JP7304938B2 (ja) 2023-07-07
CN112638346B (zh) 2024-05-28
CN112638346A (zh) 2021-04-09
EP3616675B1 (de) 2021-04-14
KR20210049105A (ko) 2021-05-04
KR102694096B1 (ko) 2024-08-09
EP3616675A1 (de) 2020-03-04
JP2022500103A (ja) 2022-01-04

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