WO2019109804A1

WO2019109804A1 - Detergent composition containing polyhydroxy compound

Info

Publication number: WO2019109804A1
Application number: PCT/CN2018/116731
Authority: WO
Inventors: 吴海龙; 雷秋芬; 李泽勇; 汤仲标; 户献雷; 郭守彬; 张利萍
Original assignee: 广州天赐高新材料股份有限公司
Priority date: 2017-12-04
Filing date: 2018-11-21
Publication date: 2019-06-13
Also published as: CN107997974A

Abstract

A detergent composition comprising the following components: (a) a surfactant accounting for 3-50% by mass of the composition; (b) a functional auxiliary accounting for 0.01-10% by mass of the composition; (c) a polyhydroxy compound accounting for 0.1-25% by mass of the composition; and (d) a solvent accounting for 40-96% by mass of the composition, the polyhydroxy compound having the following structure. The detergent composition employs the polyhydroxy compound, and is low in irritation and is mild and also has the effects of anticorrosion and functional disinfection. In addition, the polyhydroxy compound enables the detergent composition to have both conditioning and moisturizing functions.

Description

Detergent composition containing a polyhydroxy compound

Technical field

This invention relates to the field of household chemicals, and more particularly to detergent compositions containing a polyhydroxy compound.

Background technique

Preservatives must be used in order to prevent microbial growth and to achieve the necessary shelf life. The addition of an existing preservative will increase the irritation of the detergent composition and reduce the mildness of use. Currently used preservatives commonly used are parabens, carson, DMDM hydantoin, and the like.

The disadvantages of such commonly used preservatives are: limited use of the formulation, increased product irritation, increased risk of allergies to users, cumulative harm, pathogenicity, and carcinogenicity.

In the case of detergent compositions which are currently functionally sterilized, additional existing bactericides must be used to achieve their function. In addition to the higher requirements for the compounding properties of the detergent formulation, the additional bactericide also increases the irritation of the detergent composition and reduces the mildness of use. The currently used functional fungicides are zinc pyrithione, gammonomycin, piroctone, ethanolamine, ketoconazole, clopidogrel or hexamidine (hydroxylsulfonate), p-chloromethane. Phenol (PCMX), chlorhexidine, benzalkonium chloride, and the like.

Patent CN201180066751.8 uses zinc pyrithione as a sterilizing anti-dandruff agent, which requires a formulation to have a suspending ability and cannot make the formulation transparent.

The patent CN201210377379.9 uses the traditional Chinese medicine combination extract as a sterilizing anti-dandruff agent, the dandruff agent is complicated to produce, the composition stability control requirement is high, and the stability of the shampoo formulation is difficult.

Patent CN201210404271.4 uses pyrithione or gamma as a sterilizing anti-dandruff agent, and the pyrithione anti-dandruff agent needs to have a suspension ability, and the formula cannot be made into a transparent state; the granules of the granules are high in odor and the formula is strong. .

The disadvantages of such commonly used existing functional fungicides are: limited use of the formulation, increased product irritation, increased risk of allergies to users, cumulative harm, pathogenicity, and carcinogenicity.

Summary of the invention

Based on this, it is an object of the present invention to provide a detergent composition containing a polyhydroxy compound which simultaneously provides antiseptic, functional bactericidal, conditioning, and moisturizing properties.

The specific technical solutions are as follows:

A detergent composition comprising the following components:

(a) a surfactant having a compositional mass fraction of 3 to 50%;

(b) a functional auxiliary comprising 0.01-10% by mass of the composition;

(c) a polyol having from 0.1 to 25% by mass of the composition;

(d) A solvent having a compositional mass fraction of 40 to 96% (the sum of the above component contents is 100%).

In some of these embodiments, the polyol structure is as follows:

Wherein R _{1 is selected} from C ₆ -C ₂₀ alkylamide propyl, C ₆ -C ₂₀ alkylamide ethyl, C ₆ -C ₂₀ alkylacyloxyethyl, C ₆ -C ₂₀ alkane An acyloxypropyl group, a C ₆ -C ₂₀ alkyl acyloxyisopropyl group or H(OCH ₂ CH ₂ ) _n -, ₂ _{≤ n} ≤ 20; R ₂ and R ₃ are each selected from a hydroxyethyl group, C ₁ -C ₂₀ alkyl, C ₆ -C ₂₀ alkylamide propyl, C ₆ -C ₂₀ alkylamide ethyl, C ₆ -C ₂₀ alkylacyloxyethyl, C ₆ -C ₂₀ Alkyloxypropyl, C ₆ -C ₂₀ alkylacyloxyisopropyl or H(OCH ₂ CH ₂ ) _m -, ₂ ≤ _m ≤ 20, R ₄ is -OCH ₂ CH(OH)CH ₂ (OH), X is Cl or Br.

In some of these embodiments, the surfactant is selected from the group consisting of

(a) anionic surfactant, ammonium lauryl sulfate, ammonium laureth sulfate, triethylamine lauryl sulfate, triethylamine lauryl ether sulfate, sodium alkylbenzene sulfonate , ammonium alkylbenzenesulfonate, sodium aliphatic taurine, triethanolamine lauryl sulfate, triethanolamine lauryl ether sulfate, monoethanolamine lauryl sulfate, monoethanolamine lauryl sulfate, laurel Diethanolamine sulfate, lauryl polyoxyethylene ether diethanolamine, sodium laurate monosodium sulfate, sodium lauryl sulfate, sodium lauryl sulfate, fatty acid, potassium lauryl sulfate, lauryl polyoxyethylene ether Potassium sulphate, sodium lauryl sarcosinate, sodium lauroyl sarcosinate, sarcosine lauryl ester, fatty alcohol glyceryl ether sulfonate, cocoyl sarcosine, cocoyl ammonium sulphate, ammonium lauryl sulphate , sodium cocosulfate, fatty alcohol ether carboxylate, sodium lauryl sulfate, potassium cocosulfate, potassium lauryl sulfate, triethanolamine lauryl sulfate, triethanolamine lauryl sulfate, monoethanolamine cocosulfate, laurel Base sulfur Other monoamines which may be used in anionic surfactants, other than the above-mentioned sulfate, ethyl isethionate, sulfonate or sulfosuccinate, also include phosphonates, phosphates and carboxylates;

(b) amphoteric surfactant, sodium cocoamphosodium propionate, sodium cocoyl aminodipropionate, sodium cocoamphoacetate, sodium cocoamphoamphet hydroxypropyl sulfonate, cocoyl amphoteric Sodium propionate, sodium corn oleate, sodium propionate, sodium lauroamphoacetate, sodium lauroamphoacetate, sodium lauroyl amido hydroxypropyl sulfonate, sodium lauroamphopropionate, corn oleoyl amphoteric Sodium propionate, sodium lauryl iminodipropionate, ammonium cocoyl aminopropionate, ammonium cocoyl aminodipropionate, ammonium cocoamphoacetate, ammonium cocoamphodihydroxypropyl sulfonate, coconut Ammonyl oleyl ammonium propionate, ammonium corn oleyl ammonium propionate, ammonium lauryl aminopropionate, ammonium lauroamphoacetate, ammonium lauroyl amido hydroxypropyl sulfonate, ammonium lauroampholaminate, corn Ammonyl oleyl ammonium propionate, ammonium lauryl iminodipropionate, triethanolamine cocoaminopropyl propionate, triethanolamine cocoyl amino dipropionate, triethanolamine cocoamphoacetic acid, cocoyl amphoteric hydroxyl Triethanolamine propylsulfonate, triethanolamine cocoamphopropionate, corn oleate Acid triethanolamine, lauryl aminopropionic acid triethanolamine, lauroyl amido acetic acid triethanolamine, lauroyl amido hydroxypropyl sulfonic acid triethanolamine, lauroyl amphopropionic acid triethanolamine, corn oleoyl amphoteric propionic acid triethanolamine, Lauryl iminodipropionate triethanolamine, cocoyl amphodipropionic acid, disodium decanoyl diacetate, disodium decanoyl dipropionate, disodium octanoyl diacetate, octanoyl ampho Disodium dipropionate, disodium cocoamphocarboxylate, disodium cocoamphodiacetate, disodium cocoamphodipropionate, dicarboxyethyl cocoyl Disodium propylenediamine, disodium lauryl ether-5 carboxy amphoteric diacetate, disodium lauryl iminodipropionate, disodium lauroamphodiacetate, disodium lauroyl adipic dipropionate, Oil-based amphoteric dipropionate disodium, PPG-2-isodecyl ether polyether-7-carboxy amphoteric diacetate disodium, lauryl aminopropionic acid, lauroyl amphoteric dipropionic acid, lauryl aminopropyl glycine, Lauryl diethylenediaminoglycine, sodium cocoamphodiacetate, laurel Amphoteric sodium diacetate, cocamide ethyl betaine, cocamidopropyl amine oxide, cocamidopropyl betaine, cocamidopropyl dimethylaminohydroxypropyl hydrolyzed collagen, coconut Oil-amidopropyldimethylammonium hydroxypropyl hydrolyzed collagen, cocamidopropyl hydroxy sultaine, cocobetaine amidopropionate, cocobetaine, cocoyl hydroxy sulfonate Betaine, coco/oleyl propyl propyl betaine, coco sulphobetaine, lauryl propyl propyl betaine, lauryl betaine, lauryl hydroxy sultaine, lauryl sulpho beet Alkali, cocoyl sulfobetaine;

(c) Nonionic surfactants, cocamide, cocamide methyl MEA, cocamide DEA, cocamide MEA, cocamide MIPA, lauramide DEA, lauramide MEA, lauramide MIPA, tetradecylamide DEA, tetradecyl amide MEA, PEG-20 cocamide MEA, PEG-2 cocamide, PEG-3 cocamide, PEG-4 cocamide, PEG-5 cocamide, PEG-6 cocamide, PEG-7 cocamide, PEG-3 lauramide, PEG-5 lauramide, PEG-3 oleamide, PPG-2 cocamide, PPG-2 hydroxyethyl cocamide, fatty alcohol ethoxylate, fat Alcohol, alkyl glycoside;

(d) Cationic surfactant, alkyl trimethyl ammonium chloride, alkyl trimethyl ammonium bromide, alkyl trimethyl sulfate, alkyl dimethyl ethyl ammonium sulfate, fatty amide Trimethylammonium chloride, fatty amide propyl trimethylammonium bromide, fatty amide propyl trimethyl sulphate ammonium, fatty amide propyl dimethyl ethyl sulphate, alkyl dihydroxy Methyl ammonium chloride, alkyl dihydroxyethyl methyl ammonium bromide, alkyl dihydroxyethyl methyl methyl ammonium sulfate, alkyl dihydroxy ethyl ethyl ammonium sulfate, fatty amide propyl Hydroxyethyl methyl ammonium chloride, fatty acid amide propyl dihydroxyethyl methyl ammonium bromide, fatty acid amide propyl dihydroxy ethyl methyl sulfate ammonium, fatty amide propyl dihydroxy ethyl ethyl sulfate Ammonium ester, fatty amide ethyl trimethyl ammonium chloride, fatty amide ethyl trimethyl ammonium bromide, fatty acid amide ethyl trimethyl sulphate ammonium, fatty amide ethyl dimethyl ethyl sulphate , fatty amide ethyl dihydroxyethyl methyl ammonium chloride, fatty amide ethyl dihydroxyethyl methyl ammonium bromide, fatty amide ethyl dihydroxy ethyl methyl sulfate One or more of methyl ammonium ester, fatty acid amide ethyl dihydroxyethyl ethyl ammonium sulfate.

In some of these embodiments, the functional adjuvant is selected from the group consisting of a vitamin, a chelating agent, a perfume, a whitening agent, an enzyme, a conditioning agent, a thickener, an attractant, a dye, a pigment, a bleach, and a pearlizing agent. Or several.

In some of these embodiments, the solvent is selected from one or more of the group consisting of water, ethanol, glycerin, propylene glycol, polyethylene glycol, and isopropanol.

In some of the embodiments, the chelating agent is selected from the group consisting of: ethylenediaminetetraacetic acid, aminotriacetic acid, diethylenetriaminepentaacetic acid and salts thereof, citric acid, tartaric acid and gluconic acid, hydroxyethylethylene One or more of amine triacetic acid, dihydroxyethyl glycine, organic polyphosphonic acid, polyacrylic acid, polymethacrylic acid, hydrolyzed polymaleic anhydride or fumaric acid-propylenesulfonic acid copolymer.

In some of these embodiments, the conditioning agent is selected from the group consisting of cationic guar polymers, cationic non-guar galactomannan polymers, cationically modified starch polymers, acrylamide monomers, and cationic monomers. One or more of a cationic copolymer, a cationic cellulose polymer, a polysiloxane or a cationic cassia polymer.

In some of these embodiments, the thickening agent is selected from the group consisting of: modified hydroxyethyl cellulose, hydrophobically modified polyacrylate, hydrophobically modified polyacrylic acid, hydrophobically modified polyacrylamide, PEG-120 Methyl glucose dioleate, PEG-40 sorbitan tetraoleate, PEG-60 sorbitan tetraoleate, PEG-150 pentaerythritol tetrastearate, PEG-55 propylene glycol oleate or One or more of PEG-150 distearate.

In some of these embodiments, the pearling agent is selected from the group consisting of: one or both of ethylene glycol diester of stearate and ethylene glycol monoester of stearic acid.

The above detergent composition adopts the polyhydroxy compound, has antiseptic effect, does not need to additionally add existing preservative, and has low irritation and high mildness in the detergent composition; the above detergent composition can effectively kill by using the polyhydroxy compound. Malassezia, P. acnes, detergent composition has anti-dandruff and acne effect; the above detergent composition uses the polyhydroxy compound, and the detergent composition has both conditioning and moisturizing functions.

DRAWINGS

Figure 1 shows the results of the shampoo test of volunteers of Example 1 and Comparative Example 1.

Detailed ways

In order to facilitate the understanding of the present invention, the present invention will be described more fully hereinafter. However, the invention may be embodied in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the understanding of the present disclosure will be more fully understood.

All technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, unless otherwise defined. The terminology used in the description of the present invention is for the purpose of describing particular embodiments and is not intended to limit the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.

Example 1

In this embodiment, a detergent composition comprising a polyhydroxy compound is prepared:

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

b. After the phase A is dissolved uniformly, the phase B is added and heating is continued to stir and dissolve uniformly.

After the phase B is dissolved uniformly, the temperature is lowered to normal temperature, and the phase C is added, and the mixture is uniformly stirred.

Example 2

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

Example 3

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

Example 4

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

Example 5

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

Example 6

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

b. After the phase A is dissolved evenly, cool down to room temperature, add phase B, and mix well.

Example 7

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

Example 8

(1) Formulation components

(2) Formulation process

a. Heat the A phase and stir it evenly.

Comparative example 1

Comparative Example 1 The detergent composition formulation differed from Example 1 in that it did not contain a polyhydroxy compound. The results of the shampoo test of Comparative Example 1 and Example 1 volunteers are shown in Figure 1.

Volunteer shampoo test methods are as follows:

1. Trial instructions: The half-head test is to wash two kinds of shampoo at the same time in the left and right half of the shampoo, and feel the different feelings during shampooing and shampooing through both hands.

2. Trial experience point description: evaluate the corresponding indicators in the corresponding time period:

The shampooing process consists of applying shampoo, flushing, foaming, rinsing, and hair drying.

After applying the shampoo, the foam richness was evaluated; the flushing feeling was evaluated during the foaming process; the smoothness of the hair during wet hair and the softness of the hair during wet hair were evaluated after the completion of the hair rinsing; Smoothness, moisturizing feeling when dry, and softness when dry.

3. In combination with the actual use situation, give an objective score evaluation according to the following use effect evaluation indicators;

From the results of the volunteer shampoo test evaluation, it can be shown from the radar chart of Fig. 1 that the moisturizing feeling and soft feeling of Example 1 are better than that of Comparative Example 1, and the polyhydroxy compound functions as a conditioning and moisturizing effect in the detergent composition.

Comparative example 2

Comparative Example 2 The detergent composition formulation differed from Example 1 in that Carson (15 ppm addition) was used in place of the polyol.

Comparative example 3

Comparative Example 3 The detergent composition formulation differed from Example 1 in that an equivalent amount of quaternary ammonium trihydroxydipropyl ether was used in place of the polyol.

Comparative example 4

Comparative Example 4 The detergent composition formulation differed from Example 1 in that an equivalent amount of quaternary ammonium trimethyldipropyl ether was used in place of the polyol.

Comparative example 5

Comparative Example 5 The detergent composition formulation differed from Example 1 in that an equivalent amount of lauryl dimethyl hydroxypropyl glyceryl ether chloride was used in place of the polyhydroxy compound.

The anti-corrosion efficacy test data by USP32 method is as follows:

Table 1 Comparison of antiseptic efficacy test of detergent composition

Table 2 Comparison of antiseptic efficacy test of detergent composition

The detergent composition containing the polyhydroxy compound can be tested by preservative efficacy, such as the antiseptic efficacy test of Example 1 and Example 2; the antiseptic effect is substantially equivalent to Carson, see Comparative Example 2 Preservative efficacy test; without the polyhydroxy compound The detergent composition could not pass the preservative efficacy test, see Comparative Example 1 Preservative Efficacy Test. A detergent composition containing an equivalent amount of trihydroxydipropyl ether, quaternary ammonium trimethyldipropyl ether, lauryl dimethyl hydroxypropyl glyceryl ether ammonium chloride cannot pass the preservative efficacy test, see Comparative Example 3, Comparative Example 4 and Comparative Example 5 preservative efficacy test. The polyol acts as a preservative in the detergent composition.

Comparative example 6

Comparative Example 6 The detergent composition formulation differed from Example 1 in that piroctone olamine salt (0.9% added) was used in place of the polyol.

The data of bactericidal and bacteriostatic test of Malassezia furfur using QB/T2738-2012 (7.3) are as follows:

Table 3 Comparison of bactericidal and bacteriostatic tests of Malassezia

The detergent composition containing the polyhydroxy compound can be tested by the bactericidal performance of Malassezia furfur, such as the bactericidal and bacteriostatic test of Malassezia in Example 1 and Example 5; the bactericidal effect is >99%, which is substantially equivalent to pyridinium. Roxone ethanolamine, see the comparison of 6 糠秕 Malassezia bactericidal, bacteriostatic performance test; washing composition without the polyhydroxy compound can not pass the bactericidal and bacteriostatic test of Malassezia furfur, see the comparison 1糠秕Malassezia sterilization, antibacterial performance test. A detergent composition containing an equal amount of trihydroxydipropyl ether, quaternary ammonium trimethyldipropyl ether, and lauryl dimethylhydroxypropyl glyceryl ether ammonium chloride cannot pass the bactericidal and bacteriostatic test of Malassezia furfur. See Comparative Example 3, Comparative Example 4, and Comparative Example 5 for the bactericidal and bacteriostatic test of Malassezia. The polyhydroxy compound acts as a bactericidal action of Malassezia furfur in the detergent composition.

The test data of bactericidal and bacteriostatic performance of P. acnes prepared by QB/T2738-2012 (7.3) are as follows:

Table 4 Comparison of bactericidal and antibacterial properties of Propionibacterium acnes

The detergent composition containing the polyhydroxy compound can be tested for bactericidal performance of Propionibacterium acnes with a bactericidal effect of >99, as in Example 1 and Example 3, P. acnes bactericidal, bacteriostatic performance test. The detergent composition containing no such polyhydroxy compound could not pass the bactericidal and bacteriostatic test of Propionibacterium acnes, and the bactericidal and bacteriostatic test of Comparative Example 1 Propionibacterium acnes was carried out. A detergent composition containing an equal amount of trihydroxydipropyl ether, quaternary ammonium trimethyldipropyl ether, lauryl dimethyl hydroxypropyl glyceryl ether ammonium chloride cannot pass the sterilization and bacteriostatic test of P. acnes, see Comparative Example 3, Comparative Example 4 and Comparative Example 5 P. acnes sterilization and bacteriostatic performance test. The polyhydroxy compound acts as a bactericidal action of P. acnes in the detergent composition.

The technical features of the above-described embodiments may be arbitrarily combined. For the sake of brevity of description, all possible combinations of the technical features in the above embodiments are not described. However, as long as there is no contradiction between the combinations of these technical features, All should be considered as the scope of this manual.

The above-described embodiments are merely illustrative of several embodiments of the present invention, and the description thereof is more specific and detailed, but is not to be construed as limiting the scope of the invention. It should be noted that a number of variations and modifications may be made by those skilled in the art without departing from the spirit and scope of the invention. Therefore, the scope of the invention should be determined by the appended claims.

Claims

A detergent composition comprising the following components:

(a) a surfactant having a compositional mass fraction of 3 to 50%;

(b) a functional auxiliary comprising 0.01-10% by mass of the composition;

(c) a polyol having from 0.1 to 25% by mass of the composition;

(d) A solvent having a compositional mass fraction of 40-96%.
The detergent composition according to claim 1, wherein the polyhydroxy compound has the following structure:

Wherein R 1 is selected from C 6 -C 20 alkylamide propyl, C 6 -C 20 alkylamide ethyl, C 6 -C 20 alkylacyloxyethyl, C 6 -C 20 alkane An acyloxypropyl group, a C 6 -C 20 alkyl acyloxyisopropyl group or H(OCH 2 CH 2 ) n -, 2 ≤ n ≤ 20; R 2 and R 3 are each selected from a hydroxyethyl group, C 1 -C 20 alkyl, C 6 -C 20 alkylamide propyl, C 6 -C 20 alkylamide ethyl, C 6 -C 20 alkylacyloxyethyl, C 6 -C 20 Alkyloxypropyl, C 6 -C 20 alkylacyloxyisopropyl or H(OCH 2 CH 2 ) m -, 2 ≤ m ≤ 20, R 4 is -OCH 2 CH(OH)CH 2 (OH), X is Cl or Br.
A detergent composition according to claim 1 wherein said surfactant is selected from one or more of an anionic surfactant, an amphoteric surfactant, a nonionic surfactant or a cationic surfactant. .
A detergent composition according to claim 1 wherein said functional adjuvant is selected from the group consisting of vitamins, chelating agents, perfumes, whiteners, enzymes, conditioning agents, thickeners, attractants, dyes, pigments, One or more of a bleaching agent and a pearling agent.
The detergent composition according to claim 1, wherein the solvent is one or more selected from the group consisting of water, ethanol, glycerin, propylene glycol, polyethylene glycol, and isopropyl alcohol.
A detergent composition according to claim 4, wherein said chelating agent is selected from the group consisting of: ethylenediaminetetraacetic acid, aminotriacetic acid, diethylenetriaminepentaacetic acid and salts thereof, citric acid, tartaric acid And one of gluconic acid, hydroxyethylethylenediaminetriacetic acid, dihydroxyethylglycine, organic polyphosphonic acid, polyacrylic acid, polymethacrylic acid, hydrolyzed polymaleic anhydride or fumaric acid-propylenesulfonic acid copolymer Or several.
The detergent composition according to claim 4, wherein the conditioning agent is selected from the group consisting of cationic guar polymers, cationic non-guar galactomannan polymers, cationically modified starch polymers, One or more of a copolymer of an acrylamide monomer and a cationic monomer, a cationic cellulose polymer, a polysiloxane or a cationic Cassia gel polymer.
The detergent composition according to claim 4, wherein the thickener is selected from the group consisting of: modified hydroxyethyl cellulose, hydrophobically modified polyacrylate, hydrophobically modified polyacrylic acid, hydrophobically modified Polyacrylamide, PEG-120 methyl glucose dioleate, PEG-40 sorbitan tetraoleate, PEG-60 sorbitan tetraoleate, PEG-150 pentaerythritol tetrastearate One or more of PEG-55 propylene glycol oleate or PEG-150 distearate.
A detergent composition according to claim 4 wherein said pearling agent is selected from the group consisting of: one or both of ethylene glycol diester stearate and ethylene glycol monoester.