WO2018181026A1 - Élément et tête de passage d'écoulement pour scalpel électrique l'utilisant - Google Patents

Élément et tête de passage d'écoulement pour scalpel électrique l'utilisant Download PDF

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Publication number
WO2018181026A1
WO2018181026A1 PCT/JP2018/011788 JP2018011788W WO2018181026A1 WO 2018181026 A1 WO2018181026 A1 WO 2018181026A1 JP 2018011788 W JP2018011788 W JP 2018011788W WO 2018181026 A1 WO2018181026 A1 WO 2018181026A1
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WO
WIPO (PCT)
Prior art keywords
flow path
path member
roughness curve
sample
member according
Prior art date
Application number
PCT/JP2018/011788
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English (en)
Japanese (ja)
Inventor
宗幹 古賀
Original Assignee
京セラ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 京セラ株式会社 filed Critical 京セラ株式会社
Priority to US16/498,004 priority Critical patent/US20200188011A1/en
Priority to JP2019509721A priority patent/JPWO2018181026A1/ja
Priority to EP18775604.4A priority patent/EP3603554A4/fr
Publication of WO2018181026A1 publication Critical patent/WO2018181026A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/148Probes or electrodes therefor having a short, rigid shaft for accessing the inner body transcutaneously, e.g. for neurosurgery or arthroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/02Inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84Drainage tubes; Aspiration tips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00601Cutting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/1253Generators therefor characterised by the output polarity monopolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/126Generators therefor characterised by the output polarity bipolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/007Aspiration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0211Ceramics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0222Materials for reducing friction

Definitions

  • the present disclosure relates to a flow path member and an electric knife head using the same.
  • An electric knife is used in a surgical operation to remove cartilage, tumor foreign body, and the like in an affected area.
  • the electric knife has an electric knife head having an electrode for flowing a high-frequency current. Then, when using an electric scalpel, physiological saline as a conductive fluid is dropped onto the affected part, and a high-frequency current is passed from the electrode provided on the electric scalpel head to the physiological saline, thereby causing cartilage and tumor foreign matter in the affected part. Etc. can be excised.
  • a flow path member having a flow path for sucking physiological saline is used for the electric knife head.
  • Patent Document 1 proposes a head for an electric knife in which the electrode is a rod-shaped body and the electrode is arranged inside a ceramic tubular body, and the head for the electric knife has an introduction hole for guiding auxiliary liquid. .
  • the flow path member of the present disclosure has a flow path.
  • the surface of the flow path has a protruding valley depth Rvk determined from the roughness curve smaller than the protruding peak height Rpk determined from the roughness curve.
  • FIG. 2 is a cross-sectional view taken along line ii-ii in FIG.
  • the flow path of the flow path member is used not only for physiological saline but also for sucking blood and fine tissue pieces excised from the affected area.
  • the suction force may decrease. Therefore, a flow path member used as an electric scalpel head is required to have a suction force that does not easily decrease even when blood and tissue pieces are sucked.
  • the flow path member of the present disclosure is less likely to reduce the suction force even when blood and tissue pieces are sucked.
  • a flow path member of the present disclosure and an electric knife head using the same will be described in detail with reference to the drawings.
  • the electric scalpel head 10 of the present disclosure includes an electrode 2 on a flow path member 1 having a flow path 3 as shown in FIGS. 1 and 2.
  • FIG. 1 shows a monopolar type electric scalpel head 10 having one electrode 2, the present invention is not limited to this, and a bipolar electric head having a plurality of electrodes 2 is shown.
  • the female head 10 may be used.
  • required from a roughness curve is smaller than the protrusion peak height Rpk calculated
  • the protruding valley depth Rvk and protruding peak height Rpk are defined in JIS B 0671-2 (2002) and are defined as follows. First, in the central portion of the load curve including 40% of the measurement points of the roughness curve, the straight line where the dividing line of the load curve drawn with the difference in load length ratio being 40% is the most gentle is defined as the equivalent line. . Next, a core portion is defined between two height positions where the equivalent straight line intersects the vertical axis at the load length ratios of 0% and 100%. In the roughness curve, the average depth of the protruding valley portion below the core portion is the protruding valley depth Rvk. On the other hand, the average height of the protruding peak on the core is the protruding peak height Rpk.
  • the flow path member 1 of the present disclosure satisfies the above-described configuration and the average depth of the valley portion is small, the blood and tissue piece coagulated when the blood and tissue piece are sucked into the valley portion. It is difficult to accumulate and the suction force is difficult to decrease.
  • the surface 3a of the flow path 3 in the flow path member 1 of the present disclosure may have a ratio Rpk / Rvk of the protrusion valley depth Rvk and the protrusion peak height Rpk of 1.3 or more. If such a configuration is satisfied, when the blood and tissue pieces are sucked, the blood and tissue pieces coagulated in the valleys are less likely to accumulate, and therefore the suction force is less likely to decrease. Note that if the ratio Rpk / Rvk on the surface 3a of the flow path 3 is 3.0 or more, the suction force is unlikely to further decrease.
  • the protruding valley depth Rvk may be, for example, 0.2 ⁇ m or more and 1.4 ⁇ m or less.
  • the protruding peak height Rpk may be, for example, 0.7 ⁇ m or more and 2.3 ⁇ m or less.
  • the skewness Rsk obtained from the roughness curve may be positive on the surface 3a of the flow path 3 in the flow path member 1 of the present disclosure.
  • the skewness Rsk is stipulated in JIS B 0601 (2013), and is an index indicating the ratio of the peak portion to the valley portion when the average height in the roughness curve is defined as the center line. .
  • skewness Rsk is positive, it has shown that the area
  • the surface 3a of the flow path 3 in the flow path member 1 of the present disclosure has a ratio S / RSm between the average interval S of the peak portions obtained from the roughness curve and the average interval RSm of unevenness obtained from the roughness curve. 0.4 or more and 0.6 or less may be sufficient.
  • the average interval S between peak portions is defined by JIS B 0601 (1994), and is an index indicating the average value of the intervals between adjacent peak portions.
  • the average unevenness RSm is defined in JIS B 0601 (2013), and the sum of the lengths of the center lines corresponding to one peak and one adjacent valley is the peak and valley. Is an index indicating the average value of the intervals.
  • the suction force of the surface 3a of the flow path 3 in the flow path member 1 of the present disclosure is less likely to be reduced if the average interval S between the peaks is 5 ⁇ m or more and 18 ⁇ m or less. Moreover, if the surface 3a of the flow path 3 in the flow path member 1 of the present disclosure has an average unevenness RSm of 15 ⁇ m or more and 40 ⁇ m or less, the suction force is further unlikely to decrease.
  • required from the roughness curve may be 2 micrometers or less for the surface 3a of the flow path 3 in the flow path member 1 of this indication.
  • the arithmetic average roughness Ra, the skewness Rsk, and the average interval RSm of the unevenness of the surface 3a of the flow channel 3 in the flow channel member 1 of the present disclosure are based on JIS B 0601 (2013), and the average interval of the peak portions S is based on JIS B 0601 (1994), and the protruding valley depth Rvk and protruding peak height Rpk can be determined by measuring in accordance with JIS B 0671-2 (2002).
  • the measurement length may be set to 4.8 mm
  • the cut-off value may be set to 0.8 mm
  • the scanning speed of a stylus having a stylus radius of 2 ⁇ m may be set to 1.0 mm / second.
  • at least 3 or more places are measured on the surface 3a of the flow path 3, and the average value may be obtained.
  • the flow path member 1 of the present disclosure may be made of any material such as metal and resin, but if it is made of ceramics, it has excellent heat resistance.
  • ceramics silicon nitride ceramics are excellent not only in heat resistance but also in thermal conductivity and mechanical strength. If the flow path member 1 made of silicon nitride ceramics is used as a head for an electric knife, even if heating and cooling are repeated, it is less likely to be damaged, and the reliability is high.
  • the silicon nitride ceramics contain 70% by mass or more of silicon nitride out of 100% by mass of all components constituting the ceramics.
  • the material of the flow-path member 1 of this indication can be confirmed with the following method.
  • the flow path member 1 is measured using an X-ray diffractometer (XRD), and the obtained 2 ⁇ (2 ⁇ is a diffraction angle) value is identified with a JCPDS card.
  • quantitative analysis of each component constituting the flow path member 1 is performed using an ICP (Inductively Coupled Plasma) emission spectroscopic analyzer (ICP) or a fluorescent X-ray analyzer (XRF).
  • ICP Inductively Coupled Plasma
  • XRF fluorescent X-ray analyzer
  • silicon nitride ceramics if the presence of silicon nitride is confirmed, and the content converted from silicon (Si) content measured by ICP or XRF to silicon nitride (Si 3 N 4 ) is 70% by mass or more, Silicon nitride ceramics.
  • the flow path member 1 of the present disclosure will be described.
  • the flow path member 1 made of silicon nitride ceramic will be described as an example.
  • silicon nitride (Si 3 N 4 ) powder as a main raw material, yttrium oxide (Y 2 O 3 ) powder as a sintering aid and aluminum oxide (Al 2 O 3 ) powder are put in a mill together with a solvent and a ball, The slurry is pulverized until a predetermined particle size is obtained.
  • yttrium oxide powder and aluminum oxide powder calcium oxide (CaO) powder, ferric oxide (Fe 2 O 3 ) powder, tungsten oxide (WO 3 ) powder, etc. may be added as sintering aids. I do not care.
  • granules are produced by spray drying using a spray dryer.
  • the granule, thermoplastic resin, wax and the like are put into a kneader and kneaded while heating to obtain a clay.
  • the pellet used as the raw material for injection molding is obtained by throwing the obtained clay into a pelletizer.
  • the obtained pellets are put into an injection molding machine (injection molding machine) and injection molded to obtain a molded body having a through hole that becomes the flow path 3.
  • a molding die that can obtain a through-hole that becomes the flow path 3 is prepared based on a general injection molding method, and this is injected. It may be installed in a molding machine and injection molded. And since the surface property of the part which forms a through-hole in this shaping
  • molding die will be transcribe
  • the obtained molded body is fired while being held at a maximum temperature of 1700 ° C. or higher and 1800 ° C. or lower for 0.5 to 4 hours in a nitrogen gas atmosphere to obtain a sintered body.
  • the channel member 1 of this indication is obtained by carrying out barrel polishing of the surface of the obtained sintered compact.
  • baking conditions change with the shape and magnitude
  • an electric knife head 10 provided with the electrode 2 in the flow path member 1 can be obtained. .
  • samples (flow path members) having different protruding valley depth Rvk and protruding peak height Rpk were prepared, and the suction force was evaluated.
  • silicon nitride powder, yttrium oxide powder, aluminum oxide powder, ferric oxide powder and tungsten oxide powder as a sintering aid were prepared. Each powder was adjusted so that the silicon nitride powder was 84% by mass, the yttrium oxide powder was 10% by mass, the aluminum oxide powder was 4% by mass, the ferric oxide powder was 1% by mass, and the tungsten oxide powder was 1% by mass. Weighed, added water to them, put them in a mill together with balls, pulverized and mixed to prepare a slurry.
  • the surface properties of the part where the through hole is formed in the molding die installed in the injection molding machine are as follows.
  • the surface of the flow path of each sample has a protruding valley depth Rvk and a protruding peak height Rpk shown in Table 1. It was made to become.
  • this compact was fired in a nitrogen gas atmosphere at a maximum temperature of 1750 ° C. and a maximum temperature holding time of 2 hours to obtain a sintered body. Then, the obtained sintered body was barrel-polished to obtain each cylindrical sample having a diameter of 3.5 mm. The flow path of each sample was a cylindrical shape with a diameter of 1.5 mm.
  • the protrusion valley depth Rvk and protrusion peak height Rpk on the surface of the flow path are measured. Measurements were made. As measurement conditions, the measurement length was 4.8 mm, the cut-off value was 0.8 mm, and the scanning speed of a stylus with a stylus radius of 2 ⁇ m was set to 1.0 mm / second. And three places were measured on the surface of the flow path, and the average value was calculated.
  • a tube is connected to the flow path of each sample, and a solution obtained by mixing silicone with an average particle size of 13 ⁇ m, which simulates a tissue piece, into physiological saline added with glycerin to simulate the viscosity of blood is extracted from the tube.
  • the sample flowed to the flow path.
  • emitted through the flow path of each sample was passed through the particle counter, and the number of the silicone in the discharged
  • each sample was ranked in order from the one with the largest number of silicones in the discharged solution. That is, the sample with the largest number of silicones was ranked first, and the sample with the smallest number of silicones was ranked lowest. This indicates that the larger the number of silicones in the discharged solution, the more difficult the silicone cone is to collect in the flow path when sucking the silicone simulating the tissue piece, and the suction force is less likely to decrease.
  • Example 1 the skewness Rsk on the surface of the flow path was measured.
  • the measurement conditions were the same as in Example 1 based on JIS B 0601 (2013). Further, the suction force of each sample was evaluated by the same method as in Example 1.
  • Example 1 the average space
  • corrugation were measured.
  • the measurement conditions were the same as in Example 1 based on JIS B 0601 (1994) and JIS B 0601 (2013). Further, the suction force of each sample was evaluated by the same method as in Example 1.
  • sample no Among samples 16 to 20, sample no. Since the order of 17 to 19 is high, it has been found that if the average interval RSm of the unevenness on the surface of the flow path is 15 ⁇ m or more and 40 ⁇ m or less, the decrease in suction force can be further suppressed.
  • Channel member 2 Electrode 3: Channel 3a: Surface 10: Head for electric knife

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Otolaryngology (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Surgical Instruments (AREA)
  • Micromachines (AREA)

Abstract

Cet élément de passage d'écoulement comprend un passage d'écoulement. En outre, la surface du passage d'écoulement a une profondeur de vallée réduite Rvk obtenue à partir d'une courbe de rugosité qui est inférieure à une hauteur de pic réduite Rpk obtenue à partir de la courbe de rugosité.
PCT/JP2018/011788 2017-03-29 2018-03-23 Élément et tête de passage d'écoulement pour scalpel électrique l'utilisant WO2018181026A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US16/498,004 US20200188011A1 (en) 2017-03-29 2018-03-23 Flow channel member and electrosurgical knife head using the same
JP2019509721A JPWO2018181026A1 (ja) 2017-03-29 2018-03-23 流路部材およびこれを用いた電気メス用ヘッド
EP18775604.4A EP3603554A4 (fr) 2017-03-29 2018-03-23 Élément et tête de passage d'écoulement pour scalpel électrique l'utilisant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017065421 2017-03-29
JP2017-065421 2017-03-29

Publications (1)

Publication Number Publication Date
WO2018181026A1 true WO2018181026A1 (fr) 2018-10-04

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PCT/JP2018/011788 WO2018181026A1 (fr) 2017-03-29 2018-03-23 Élément et tête de passage d'écoulement pour scalpel électrique l'utilisant

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US (1) US20200188011A1 (fr)
EP (1) EP3603554A4 (fr)
JP (1) JPWO2018181026A1 (fr)
WO (1) WO2018181026A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3845176A4 (fr) * 2018-08-30 2022-05-18 Kyocera Corporation Tête de scalpel électrique

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002136526A (ja) 2000-10-30 2002-05-14 Kyocera Corp 電気メス用ワンドヘッド
US20130190699A1 (en) * 2012-01-20 2013-07-25 Rabie Stephan Anti-biofilm intravascular catheter
WO2015053365A1 (fr) * 2013-10-09 2015-04-16 オリンパスメディカルシステムズ株式会社 Instrument de traitement haute-fréquence pour endoscope

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6832996B2 (en) * 1995-06-07 2004-12-21 Arthrocare Corporation Electrosurgical systems and methods for treating tissue
JP6049003B2 (ja) * 2012-04-12 2016-12-21 Towa株式会社 梨地面の形成方法、樹脂成形型及び低密着性材料
US9603656B1 (en) * 2015-10-23 2017-03-28 RELIGN Corporation Arthroscopic devices and methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002136526A (ja) 2000-10-30 2002-05-14 Kyocera Corp 電気メス用ワンドヘッド
US20130190699A1 (en) * 2012-01-20 2013-07-25 Rabie Stephan Anti-biofilm intravascular catheter
WO2015053365A1 (fr) * 2013-10-09 2015-04-16 オリンパスメディカルシステムズ株式会社 Instrument de traitement haute-fréquence pour endoscope

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3603554A4

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EP3603554A4 (fr) 2021-01-13
US20200188011A1 (en) 2020-06-18
EP3603554A1 (fr) 2020-02-05
JPWO2018181026A1 (ja) 2020-02-06

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