WO2017186190A1 - 支架、支撑系统、血栓弹力仪及其使用方法 - Google Patents
支架、支撑系统、血栓弹力仪及其使用方法 Download PDFInfo
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- WO2017186190A1 WO2017186190A1 PCT/CN2017/082786 CN2017082786W WO2017186190A1 WO 2017186190 A1 WO2017186190 A1 WO 2017186190A1 CN 2017082786 W CN2017082786 W CN 2017082786W WO 2017186190 A1 WO2017186190 A1 WO 2017186190A1
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- support
- connecting portion
- light
- rotating shaft
- support portion
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
- G01N11/14—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
- G01N11/14—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
- G01N2011/147—Magnetic coupling
Definitions
- the invention relates to the field of detection technology, in particular to a stent, a support system, a thromboelastometer and a method of using the same.
- the thromboelastometer is a device for detecting blood clot parameters in vitro, and includes a rotatable rotating shaft.
- the rotating shaft When detecting blood, the rotating shaft is inserted into the blood, and the rotating shaft is rotated by the rotation of the blood.
- the elastic force of the blood is calculated according to the angular displacement of the rotating shaft, thereby providing objective guidance for the clinical diagnosis of diseases such as cardiovascular and cerebrovascular diseases.
- the rotating shaft on the thromboelastometer is connected to the bracket, and the rotating shaft is rotated by the blood by the support of the bracket.
- Embodiments of the present invention provide a stent, a support system, a thromboelastometer, and a method of using the same, which can easily adjust an angular offset to improve measurement accuracy.
- a bracket comprising: a first support portion, a second support portion, and a connecting portion, wherein:
- the first supporting portion supports the second supporting portion through the connecting portion, so that the second supporting portion can rotate relative to the first supporting portion under a first force
- the first support portion includes: a rotatable structure, a support base and a stop mechanism, wherein:
- the stop mechanism is for providing a blocking effect on the rotation of the rotatable structure
- the rotatable structure is supported on the support base and is rotatable relative to the support base under a second force in the event that the blocking action of the stop mechanism is eliminated;
- the rotatable structure supports the second support portion through the connecting portion such that the rotatable structure is rotatable relative to the second support portion when rotated relative to the support seat.
- a thromboelastometer comprising a bracket as described above and a rotating shaft, wherein a lower end of the second supporting portion is coupled to one end of the rotating shaft to support the rotating shaft,
- the rotating shaft is enabled to rotate under external driving.
- a support system comprising the bracket and the supported object as described above, wherein a lower end of the second support portion is connected to one end of the supported object
- the support is supported to enable the support to rotate under external driving.
- a thromboelastometer as described above, comprising:
- the blood coagulation data of the blood to be measured is calculated based on the measured rotation angle of the rotation axis.
- connection portion of the bracket connecting the first support portion and the second support portion is such that the two are relatively rotatable, and the first support portion carries the connection portion
- the bridge structure is located on the rotatable first support member, and the first support member is rotated by applying a suitable external force to the first support member in the case of eliminating the blocking action of the stop mechanism on the rotation of the movable structure.
- the bridge structure is rotated relative to the second support portion, so that the bridge structure can be conveniently adjusted to be at a predetermined angle with the second support portion to eliminate various portions of the thrombelometer (eg, the first support portion and the second support portion)
- the angular offset between them improves the measurement accuracy.
- FIG. 1 is a schematic block diagram of a bracket in accordance with one embodiment of the present invention.
- FIGS. 2A-B are schematic structural views of a stent according to an embodiment of the present invention.
- 3A-C are schematic structural views of a first support portion of a stent according to an embodiment of the present invention.
- FIG. 4 is a schematic structural view of a second support portion of a bracket according to an embodiment of the present invention.
- Figure 5 is a schematic view showing the structural composition of a thromboelastometer including a stent according to an embodiment of the present invention
- Figure 6 is a schematic view showing the composition of a connecting portion according to an embodiment of the present invention.
- Figure 7 is a schematic view of a joint of a jewel bearing fixedly coupled to a first support portion in accordance with one embodiment of the present invention
- Figure 8 is a schematic view showing a connecting portion of a jewel bearing fixedly coupled to a second support portion according to an embodiment of the present invention
- Figure 9 is a schematic view of a connecting portion including a magnet according to an embodiment of the present invention.
- Figure 10 is a schematic diagram showing the composition of a thromboelastometer including a measuring device according to an embodiment of the present invention
- FIG. 11 is a schematic diagram showing the composition of a thromboelastometer including a light emitting diode and a photocell according to an embodiment of the present invention
- Figure 12 is a flow chart of a method of using a thromboelastometer in accordance with one embodiment of the present invention.
- Figure 13 is a schematic block diagram of a support system in accordance with one embodiment of the present invention.
- first and second are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated.
- features defining “first” or “second” may include one or more of the described features, either explicitly or implicitly.
- the meaning of “plurality” is two or more unless specifically and specifically defined.
- an embodiment of the present invention provides a bracket including: a first support portion 1001, a second support portion 1003, and a connecting portion 1002, wherein:
- the first supporting portion 1001 supports the second supporting portion 1003 through the connecting portion 1002 such that the second supporting portion 1003 can rotate relative to the first supporting portion 1001 under a first force;
- the first support portion 1001 includes a rotatable structure 1004, a support base 1013, and a stop mechanism 1024, wherein:
- the stopping mechanism 1024 is configured to block rotation of the rotatable structure
- the rotatable structure 1004 is supported on the support base 1013, and is rotatable relative to the support base 1013 under a second force in a case where the stopping action of the stopping mechanism 1024 to the rotation is eliminated; as well as
- the rotatable structure 1004 supports the second support portion 1003 through the connecting portion 1002 such that the rotatable structure 1004 is rotatable relative to the second support portion 1003 when rotated relative to the support base 1013.
- the rotatable structure 1004 includes a first support 1012 and a bridge structure 1011, wherein:
- the first support member 1012 is supported on the support base 1013 and is capable of being opposite to the support base 1013 under the second force under the condition that the stopping action of the stopping mechanism 1024 to the rotation is eliminated.
- the bridge structure 1011 is supported on the first support 1012 and is fixedly coupled to the first support 1012 such that the bridge structure 1011 can follow when the first support 1012 rotates Rotate together;
- the bridge structure 1011 supports the second support portion 1003 through the connecting portion 1002 such that the bridge structure 1011 can rotate relative to the second support portion 1003 when the first support member 1012 rotates.
- the rotatable structure consisting of the first support member and the bridge structure is only an example, it being understood that the rotatable structure may have other structures.
- the stop mechanism 1024 can be implemented by various means, for example, the stop mechanism 1024 It can be selected from one of the following or any combination of them:
- a fixing member for fixing the rotatable structure 1004 with respect to the support base 1013 such as a screw, a latch structure, a rope, or the like.
- the fastener can be released when needed to eliminate the blocking effect on the rotation of the rotatable structure 1004.
- the blocking action of the rotation of the rotatable structure 1004 can be provided by appropriate friction between the rotatable structure 1004 and the contact surface of the support base 1013.
- the predetermined roughness may provide a frictional force between the contact surfaces to provide the blocking effect.
- the contact surfaces of both can be machined to have a certain roughness to provide adequate friction.
- a surface having a predetermined roughness includes a material or structure that is attached, adhered, or machined to a contact surface for providing or increasing friction. When necessary, the frictional force can be cancelled by applying an opposite external force, thereby eliminating the blocking effect on the rotation of the rotatable structure 1004.
- a material that provides a viscous viscous force between the rotatable structure 1004 and the contact surface of the support base 1013 may be provided between the rotatable structure 1004 and the contact surface of the support base 1013, the viscous force provided by these materials being offset by external forces, when the external force disappears The viscous force continues to prevent rotation of the rotatable structure 1004.
- stop mechanism 1024 are not exhaustive. Other various means of implementation that enable the functionality of the stop mechanism 1024 described herein can be foreseen by those skilled in the art.
- FIG. 2A is a schematic view showing the structural composition of a stent according to an embodiment
- FIG. 2B is a cross-sectional view of FIG. 2A
- 3A-3C are schematic diagrams showing the composition of the first support portion of the stent of FIG. 2, wherein FIG. 3A is a schematic view of the support base, FIG. 3B is a schematic view of the first support member, and FIG. 3C is a schematic view of the bridge structure.
- 4 is a schematic view showing the composition of a second support portion of the stent of FIG. 2.
- the bracket is constituted by a first support portion and a second support portion 1003 that are connected by a connecting portion 1002.
- the first support portion includes a support base 1013, a first support member 1012 positioned thereon and rotatably coupled thereto, and a bridge structure 1013 supported by the first support member 1012.
- the first support portion is connected to the connecting portion 1002 through the bridge structure 1013 to support the second support portion 1003 that is also connected to the connecting portion 1002.
- the connecting portion 1002 is configured such that the second supporting portion 1003 can be at the first force (for example, when the bracket is used for the thromboelastometer, the first force can be the rotation of the rotating shaft caused by the rotation of the blood to be measured.
- the first support portion is rotated such that the second support portion 1003 can be rotated when the supported object fixedly coupled to the lower end of the second support portion 1003 is driven by an external force to rotate.
- stop mechanism 1024 of FIG. 1 is not explicitly shown in FIGS. 2-4 for clarity of the graphics. It will be appreciated that the stop mechanism 1024 can be any of the above mentioned implementations in the examples of Figures 2-4.
- the first support 1012 includes a support surface 1012a and a cylindrical extension 1012b positioned below and coupled to the support surface 1012a, wherein the top surface dimension of the cylindrical extension 1012b is less than the size of the support surface 1012a, ie The support surface 1012a extends beyond the upper surface of the cylindrical extension 1012b such that the support surface 1012a protrudes beyond the side surface of the cylindrical extension 1012b.
- the center of the first support 1012 has a first through hole 1015, and the bridge structure 1011 is fixed to the first support 1012 across the first through hole 1015.
- the bridge structure 1011 can be secured to the first support 1012 by a variety of means with or without the aid of various connectors. For example, at least one card slot may be provided on the support surface 1012a of the first support member 1012, and at least one end of the bridge structure 1011 may be placed in the at least one card slot.
- the bridge structure 1011 can also be secured to the first support 1012 using screws. Or use the combination of the above two methods.
- the bridge structure 1011 can also be secured by welding, bonding, or by means of other connectors and/or fasteners.
- the support surface 1012a of the first support member 1012 has two card slots 1017, and the two ends of the bridge structure 1011 are respectively disposed in the two card slots 1017.
- the ends of the bridge structure 1011 are also secured to the first support 1012 using screws in this example.
- the bridge structure 1011 is shown as a sunken bridge structure in which the upper surface of the bridge structure 1011 is substantially flush with the support surface 1012a of the first support 1012, with the upper surface below
- the sinking portion is provided with an opening 1018 extending to the sinking portion for fixing the connecting portion 1002.
- the bridge structure 1011 can also employ other structures, such as a floating structure, wherein the lower surface of the bridge structure 1011 is substantially flush with the support surface 1012a of the first support 1012, the lower surface There is an upper floating portion, and an upper surface is provided with an opening extending to the upper floating portion for fixing the connection connecting portion 1002.
- the support base 1013 has a top surface 1021 having a groove or second through hole 1014 that matches the cylindrical extension 1012b of the first support 1012 such that the cylindrical extension 1012b It can be accommodated in the groove or the second through hole 1014.
- the rotatably connected first support 1012 to the support base 1013 can be achieved using a variety of attachment means. For example, a rotary bearing or a plain bearing can be used.
- FIGS. 2-4 after assembly, the first support 1012 is in direct contact with the support base 1013, and the cylindrical extension 1012b of the first support 1012 is received in the second through hole 1014 at the center of the support base 1013.
- the support surface 1012a of the first support member 1012 is supported on the top surface 1021 of the support base 1013. Wherein, after the blocking action of the stopping mechanism on the rotation of the first support member 1012 is eliminated, the first support member 1012 is rotatable relative to the support base 1013 when a suitable external force for rotating the first support member 1012 is applied.
- the support surface 1012a of the first support 1012 is shown extending beyond the upper surface of the cylindrical extension 1012b in the example of FIGS. 2-4 to contact the top surface 1021 of the support base 1013 after assembly with the support base 1013 and Supported by it.
- the first support member 1012 can take other forms.
- the size of the support surface 1012a can be equal to the size of the upper surface of the columnar extension 1012b.
- the groove or the second pass The bottom surface of the aperture 1014 contacts the bottom surface of the cylindrical extension 1012b and provides support.
- the first support member is cylindrical and the recess or through hole of the support seat has at least a portion of the bottom surface to provide support for the first support member.
- the support surface 1012a of the first support member 1012 is circular, the cylindrical extension portion 1012b is cylindrical, and the support base 1013 is also cylindrical.
- the support surface 1012a of the first support member 1012 can be any shape, and the cylindrical extension 1012b and the support base 1013 can be other suitable shapes as long as the first support member 1012 and the support base can be realized.
- the 1013's rotatable connection is sufficient.
- the support base 1013 and the center of the first support member 1012 each have a through hole, and the first through hole 1015 and the second through hole 1014 at least partially coincide with each other for the second support portion.
- 1003 at least partially passes through the first through hole 1015 and the second through hole 1014 (see FIGS. 2A-B). It can be understood that, in the case that the second support portion 1003 does not need to pass through the first support portion 1001, the support base 1013 and the first support member 1012 may not have a through hole.
- the center of the second support portion 1003 also has a through hole, that is, a third through hole 1016.
- a notch 1022 is provided on a side wall of the third through hole 1016 near the upper end of the second support portion 1003 for connection with the connecting portion 1002.
- the third through hole 1016 is illustrated as a square shape in FIG. 4, it being understood that it may be any other suitable shape.
- the second support portion 1003 passes through the first through hole 1015 of the first support member 1012 and the second through hole 1014 of the support base 1013 when being supported by the first support portion 1001, The lower end of the second support portion 1003 passes through the support base 1013.
- the bridge structure 1011 passes through the third through hole 1016 of the second support portion 1003 to support the second support portion 1003 through the connection portion 1002.
- the apertures 1018 on the bridge structure 1011 are aligned with the notches 1022 on the second support portion 1003 and are respectively connected to the connection portion 1002.
- the connecting portion 1002 is located in the third through hole 1016 of the second supporting portion 1003.
- bracket structure and assembly manner are only an example. It can be understood that the second support portion may not pass through the first and second through holes, but the second support portion and the third through hole thereof are large enough to be The entire first support portion is passed through the third through hole, that is, the four frames of the third through hole are located outside the first support portion.
- connection portion 1002 can include a first connection portion 1019 and a second connection portion 1020, wherein the first connection portion 1019 is fixedly coupled to the bridge structure 1011 (eg, through the aperture 1018 on the bridge structure 1011)
- the second connecting portion 1020 is fixedly coupled to the second supporting portion 1003 (for example, through the notch 1022 on the second supporting portion 1003).
- the first connecting portion 1019 and the second connecting portion 1020 are connected in point contact such that the first connecting portion 1019 and the second connecting portion 1020 can be relatively rotated, so that the second supporting portion 1003 can be opposite to the bridge structure 1011. Turn.
- the first supporting portion supports the second supporting portion and the object to be supported by the connecting portion, and the first connecting portion 1019 and the second connecting portion 1020 of the connecting portion are connected by point contact.
- the supported object is fixedly coupled to the second support portion and drives the second support portion 1003 to rotate around a contact point between the first connecting portion 1019 and the second connecting portion 1020 after being driven by an external force. Since the first connecting portion 1019 and the second connecting portion 1020 are connected by point contact, only one contact point generates a frictional force to hinder the second supporting portion when the first supporting portion 1001 and the second supporting portion 1003 are relatively rotated.
- the rotation of 1003 can reduce the friction generated on the bracket, thereby reducing the rotational resistance that is received when the support is rotated.
- the point contact may be in a manner that the two contact members are not in full contact and the contact area is less than a predetermined value.
- the contact area is less than 1 square millimeter.
- Fig. 6 shows a schematic view of the connection portion of the jewel bearing 3031 and the top cone 3032 of the first connecting portion and the second connecting portion.
- the jewel bearing 3031 is provided with a tapered groove 2011, the top cone 3032 is a tapered structure, the tip end of the top cone 3032 is located in the tapered groove 2011 on the jewel bearing 3031, and the top cone 3032 is engaged with the jewel bearing 3031 in point contact form. .
- the jewel bearing 3031 has a disk-shaped structure, and a tapered groove 2011 is provided on one plane of the jewel bearing 3031, and the top cone 3032 has a tapered structure.
- Top cone 3032 The tip is located in the recess 2011, and only the tip end of the top cone 3032 is in contact with the bottom of the recess 2011, so that the jewel bearing 3031 and the top cone 3032 are connected by point contact.
- the tip end of the tip cone 3032 has an area of 0.8 square millimeters through which the tip end of the area of 0.8 square millimeters is in point contact with the tapered groove 2011 of the jewel bearing 3031.
- the first connecting portion in the connecting portion is a jewel bearing
- the second connecting portion is a top cone
- the first connecting portion is a top cone and the second connecting portion is a jewel bearing.
- the jewel bearing 3031 is fixedly connected to the first supporting portion 1001 as a first connecting portion
- the top cone 3032 is fixedly connected to the second supporting portion 1003 as a second connecting portion
- the tip end of the top cone 3032 is located in the gemstone.
- the tip end of the top cone 3032 is in point contact with the bottom of the groove of the jewel bearing 3031.
- the first support portion 1001 supports the fixedly connected top cone 3032 and the second support portion 1003 via the jewel bearing 3031.
- the top cone 3032 is fixedly connected to the first supporting portion 1001 as a first connecting portion
- the jewel bearing 3031 is fixedly connected to the second supporting portion 1003 as a second connecting portion
- the tip end of the top cone 3032 is The bottom of the jewel bearing 3031 is point contact.
- the first support portion 1001 supports the fixedly connected jewel bearing 3031 and the second support portion 1003 via the top cone 3032.
- the bracket further comprises: at least one pair of magnets
- a first magnet of the pair of magnets is fixed to a side of the first support portion adjacent to the second support portion, and a second magnet of the pair of magnets is fixed to the second support portion near the first support portion One side;
- the first magnet and the second magnet are stacked in parallel, and the two adjacent surfaces are the same magnetic poles.
- the bracket includes two pairs of magnets, the first pair of magnets includes a magnet 5041 and a magnet 5042 , and the second pair of magnets includes a magnet 5051 and a magnet 5052 .
- the magnet 5041 and the magnet 5051 are fixed to the first supporting portion 1001 .
- the magnet 5042 and the magnet 5052 are fixed to the second support portion 1003.
- the magnets 5041 of the first pair of magnets are stacked in parallel with the magnets 5042.
- the surfaces of the magnets 5041 and 5042 that are close to each other have magnetic poles of the same polarity.
- the N pole of the magnet 5041 is directed to the second support portion 1003, and the N pole of the magnet 5042.
- the magnet 5051 of the second pair of magnets is stacked in parallel with the magnet 5052, and the faces of the magnet 5051 and the magnet 5052 are close to each other with magnetic poles of the same polarity.
- the S pole of the magnet 5051 points to the second support portion. 1003.
- the S pole of the magnet 5052 is directed to the first support portion 1001.
- the bracket further includes a fixed upright 1023 for supporting the first support portion 1001 and the second support portion 1003, wherein the support base 1013 is fixedly coupled to the fixed upright 1023.
- the second support portion can be applied to the first Rotating relative to the first support portion (for example, the bridge structure of the first support portion) under a force, so that when the lower end of the second support portion is connected with the support, the rotation of the support can drive the second support portion to be relatively Rotating at the first support portion.
- the first support portion remains stationary, whereby the rotation angle of the supported object can be measured by measuring the rotation angle of the second support portion.
- the blocking action of the stop mechanism on the rotation can be eliminated (for example, loosening the fixing member and canceling the frictional force) And/or viscous force, etc.), after which the rotatable structure is rotatable relative to the second support portion under a second force applied thereto (eg, the first support member can be driven under a second force applied thereto)
- the bridge structure is rotated relative to the second support portion such that the first support portion (eg, the bridge structure) and the second support portion are in a predetermined positional relationship by manually rotating the rotatable structure (eg, the first support member) To ensure the accuracy of the measurement.
- the first support portion and the second support portion are arranged such that the longitudinal direction axis of the bridge structure is perpendicular to the plane of the second support portion.
- the bracket including the rotatable bridge structure according to the present invention it is possible to apply an appropriate external force to the first support member to be fixedly connected thereto after eliminating the blocking action of the stopper mechanism against the rotation.
- the bridge structure is rotated at an angle relative to the second support such that the axis of the bridge structure thereon becomes perpendicular to the second support.
- bridge structure refers to a structure in which the structure spans the surface supporting it, and it should be noted that the surface supporting it may have a slot, an opening or a through hole for the bridge structure to span, but these Grooves, openings, through holes or the like are not required.
- FIG. 5 illustrates an embodiment of a thromboelastometer comprising the stent described above.
- the thromboelastometer includes a bracket and a rotating shaft 7 as a supported object supported by the bracket.
- the lower end of the second support portion 1003 is coupled to one end of the rotating shaft 7 to support the rotating shaft 7, so that the rotating shaft 7 can be rotated by external driving.
- the other end (lower end) of the rotary shaft 7 projects into the blood to be measured accommodated in the container, and the blood is driven to rotate by the driving means, thereby causing the rotary shaft 7 to also rotate.
- the thromboelastometer can calculate the blood coagulation parameter data of the blood to be measured by measuring the rotation angle of the rotating shaft 7.
- the thromboelast apparatus further includes a measuring device, wherein the measuring device is configured to measure a rotation angle of the rotating shaft, and form a corresponding to the Blood pressure thrombus map.
- the measuring device includes: at least one light reflecting sheet 51, at least one light emitting module 52, at least one light receiving module 53 and a processing module 54;
- the rotating shaft 7 is fixedly connected to the at least one reflector 51, and the rotating shaft 7 drives the at least one reflector 51 to rotate under external driving;
- Each of the light emitting modules 52 is configured to emit light to the corresponding retroreflective sheet 51 in a fixed direction;
- Each of the retroreflective sheetings 51 is configured to receive light emitted by the corresponding light emitting module 52 and reflect the received light;
- Each light receiving module 53 is configured to receive the light reflected by the corresponding reflector 51 in a fixed direction, convert the received light into a corresponding electrical signal according to the intensity of the light, and transmit the electrical signal to the processing module 54;
- the processing module 54 is configured to process the electrical signals converted by the at least one light receiving module 53 to determine the rotation angle of the rotating shaft 7.
- the light reflecting sheet reflects the light emitted by the light emitting module to the light receiving module, and when the reflecting sheet rotates under the rotation of the rotating shaft, the light emitting module emits light in a fixed direction, and the reflecting sheet
- the amount of received light changes, and the optical path of the reflected light of the retroreflective sheet changes due to the rotation of the retroreflective sheeting, resulting in a change in the intensity of the light received by the light receiving module that receives the light in a fixed direction, and the light receiving module is based on the light.
- the intensity of the received light is converted into a corresponding electrical signal, and the processing module determines the angle of rotation of the rotating shaft based on the electrical signal.
- the light is used as the signal for detecting the rotation angle of the rotating shaft, and since the intensity of the light does not change with the change of external factors such as temperature, the rotation angle of the rotating shaft can be detected by the light, and the rotation angle of the rotating shaft can be improved. accuracy.
- the light emitting module 52 includes a light emitting diode 6031 and a light guiding column 6032 , wherein the light emitting diode 6031 emits light to the light reflecting sheet 51 through the light guiding column 6032;
- the light receiving module 53 includes a photocell 6041 and a light guiding column 6042.
- the photocell 6041 receives the light emitted by the retroreflective sheeting 51 through the light guiding column 6042.
- the inner surface of the fourth through hole 6062 in which the light emitting module 52 is located is a machined surface, there is a certain roughness. If the light is directly emitted to the light reflecting sheet 51 through the light emitting diode 6031, the light emitting diode 6031 The emitted light is diffusely reflected in the fourth through hole 6062, which causes loss of light energy on the one hand, and causes the direction and amount of light emitted from the fourth through hole 6062 to be difficult to control on the other hand.
- the light emitted by the light-emitting diode 6031 is directed to the retroreflective sheet 51 through the light guide column 6032, and the light emitted by the light-emitting diode 6031 is conducted inside the light guide column 6032.
- Light does not cause diffuse reflection, thereby improving the utilization of light energy, and ensuring that the light emitted from the fourth through hole 6062 has a specific direction and a specific amount, thereby ensuring the accuracy of detecting the rotation angle of the rotating shaft 7. .
- each of the light receiving modules includes a photovoltaic cell and a light guiding column, and the photocell and the light guiding column are both fixed in the fifth through hole, wherein the light guiding column is located on a side close to the reflective sheet.
- the light guide column receives the light reflected by the corresponding reflector in a fixed direction, and transmits the received light to the photocell, and the photocell converts the received light into a corresponding electrical signal according to the intensity of the light.
- the inner surface of the fifth through hole 6063 has a certain roughness, and if the light reflected by the retroreflective sheet 51 directly enters the fifth through hole 6063.
- the photocell 6041 When the photocell 6041 is reached, the light is diffusely reflected on the inner wall of the fifth through hole 6063, causing the loss of light energy, and finally the energy of the light reaching the photocell 6041 is smaller than the energy of the light of the retroreflective sheet entering the fifth through hole 6063.
- the light reflected by the retroreflective sheeting 51 is received by the light guiding column 6042, and the light is transmitted inside the light guiding column 6042.
- the light does not diffusely reflect during the transmission, and the energy of the light received by the photocell 6041 and the reflective sheet 51 are reflected to the light guiding column 6042.
- the energy of the light is equal, so that the accuracy of detecting the angle of rotation of the rotating shaft 7 can be ensured.
- the thromboelast apparatus further includes at least one light blocking sheet, the number of the light blocking sheets being equal to the number of the light guiding columns, and each of the light blocking sheets corresponding to one of the light guiding columns.
- the light blocking plate is provided with a fixed shape and a fixed size light passing hole.
- the light blocking piece is disposed between the reflective sheet and the light guiding column, so that the light reflected by the reflective sheet can only be emitted to the light guiding rod through the light passing hole on the light blocking sheet.
- Figure 12 shows a flow chart of a method of using the thromboelastometer described above, in accordance with one embodiment of the present invention. As shown in FIG. 12, the method includes:
- Step S121 canceling the blocking action of the stopping mechanism in response to the first supporting portion being offset from the second supporting portion by a predetermined position
- Step S122 rotating the first support member by applying a second force to the first support member, so that the bridge structure is rotated relative to the second support portion to be opposite to the second support portion. a position at a predetermined angle;
- Step S123 inserting the lower end of the rotating shaft into the blood to be tested
- Step S124 rotating the blood to be measured to drive the rotating shaft to rotate;
- Step S125 Calculate blood clot data of the blood to be measured based on the measured rotation angle of the rotation axis.
- FIG. 13 shows a block diagram of the composition of such a support system.
- the support system includes a bracket 1301 and a supported object 1302, wherein a lower end of the second support portion of the bracket 1301 is coupled to one end of the supported object 1302 to support the supported object 1302, so that the supported object 1302 can be supported. Rotate under the action of external drive.
- the second support portion is rotatable relative to the first support portion under a first force applied thereto, such that when the lower end of the second support portion is connected with the support, the support is The rotation can drive the second support portion to rotate together with respect to the first support portion.
- the first support portion remains stationary, whereby the rotation angle of the supported object can be measured by measuring the rotation angle of the second support portion.
- the blocking action of the stop mechanism on the rotation can be eliminated (for example, loosening the fixing member and canceling the frictional force) And/or viscous force, etc.), after which the rotatable structure is rotatable relative to the second support portion under a second force applied thereto, thereby enabling manual rotation of the rotatable structure (eg, the first support member)
- the first support portion (for example, the bridge structure) and the second support portion are in a predetermined positional relationship to ensure the accuracy of the measurement.
- the first supporting portion supports the second supporting portion and the supported object through the connecting portion, and the first connecting portion and the second connecting portion of the connecting portion are connected by point contact, and are supported After the object is forced, the second support portion is driven to rotate around a contact point between the first connecting portion and the second connecting portion. Since the first connecting portion and the second connecting portion are connected by point contact, only one contact point generates a frictional force to hinder the rotation of the second supporting portion when the second supporting portion and the first supporting portion rotate relative to each other. The friction generated on the bracket is reduced, thereby reducing the rotational resistance that is received when the support is rotated.
- the connecting portion includes two connecting portions which may be a jewel bearing and a top cone, and the tip end of the top cone is located in the tapered groove of the jewel bearing, the tip end of the top cone and the bottom of the tapered groove
- the friction generated by the jewel bearing and the top cone is relatively high. It is small, so that the rotation resistance from the stent when the support is rotated can be reduced, and the sensitivity and measurement accuracy of the thrombometer can be improved when the stent is applied to the thromboelastometer.
- the bracket may include at least one pair of magnets, one of each pair of magnets is fixed on the first support portion, and the other magnet is fixed on the second support portion, and the pair of magnets are stacked in parallel And the same magnetic poles are opposite, such that, according to the principle of homosexual repelling, the magnet on the first supporting portion gives an upward magnetic force to the magnet on the second supporting portion, and the magnetic force can reduce the point contact between the first connecting portion and the second connecting portion.
- the pressure between the points reduces the pressure between the point contacts to further reduce the friction generated by the point contact, thereby further reducing the rotational resistance experienced when the support is rotated.
- the reflector reflects the light emitted by the light emitting module to the light receiving module.
- the light emitting module emits light in a fixed direction
- the reflective sheet receives The amount of light that is changed changes, and at the same time, the optical path of the light reflected by the retroreflective sheet changes due to the rotation of the retroreflective sheeting, so that the intensity of the light received by the light receiving module receiving the light in a fixed direction changes, and the light receiving module is based on the light.
- the intensity converts the received light into a corresponding electrical signal
- the processing module determines the angle of rotation of the rotating shaft based on the electrical signal.
- the light is used as the signal for detecting the rotation angle of the rotating shaft, and since the intensity of the light does not change with the change of external factors such as temperature, the rotation angle of the rotating shaft can be detected by the light, and the rotation angle of the rotating shaft can be improved. accuracy.
- the light emitting diode emits light through the light guiding column
- the photocell receives light through the light guiding column
- the light guiding column acts as a channel of light to enhance light uniformity and prevent light from occurring in the through hole of the fixed light emitting diode or the photovoltaic cell. Diffuse reflection, which affects the intensity of the light, so as to ensure the accuracy of detecting the rotation angle of the rotating shaft.
- processor capable of executing appropriate program instructions, arithmetic operations, data processing, and the like. / or appropriate means of controlling operations, etc., which may be software, hardware, firmware or a combination thereof such as, for example, a computer, a central processing unit, or the like. They may be composed of a single component or a case where their functions are dispersed over a plurality of components. It can be a centralized processing system or a distributed processing system.
- a bracket comprising: a first support portion, a second support portion and a connection portion, wherein:
- the first supporting portion supports the second supporting portion through the connecting portion, so that the second supporting portion can rotate relative to the first supporting portion under a first force
- the first support portion includes: a rotatable structure, a support base and a stop mechanism, wherein:
- the stop mechanism is for providing a blocking effect on the rotation of the rotatable structure
- the rotatable structure is supported on the support base and is rotatable relative to the support base under a second force in the event that the blocking action of the stop mechanism is eliminated;
- the rotatable structure supports the second support portion through the connecting portion such that the rotatable structure is rotatable relative to the second support portion when rotated relative to the support seat.
- the rotatable structure comprises a first support member and a bridge structure, wherein:
- the first support member is supported on the support base and is rotatable relative to the support base under the second force when the blocking action of the stop mechanism is eliminated;
- the bridge structure is supported on the first support and fixedly coupled to the first support such that the bridge structure can rotate together as the first support rotates;
- the bridge structure supports the second support portion through the connecting portion such that the bridge structure is rotatable relative to the second support portion when the first support member rotates.
- a fixing member for fixing the rotatable structure relative to the support base
- a material that provides a releasable viscous force between the rotatable structure and the contact surface of the support is
- the center of the first support member has a first through hole, and the bridge structure is fixed to the first support member across the first through hole;
- the center of the support base has a second through hole that at least partially coincides with the first through hole
- a center of the second support portion has a third through hole
- the second support portion passes through the first through hole and the support when being supported by the first support portion
- the second through hole is described, and the bridge structure supports the second support portion through the connection portion located in the third through hole through the third through hole.
- the connecting portion includes a first connecting portion and a second connecting portion
- the first connecting portion is fixedly connected to the bridge structure, and the second connecting portion is fixedly connected to the second supporting portion;
- the first connecting portion and the second connecting portion are connected in a point contact manner such that the first connecting portion and the second connecting portion are relatively rotatable, so that the second supporting portion and the second connecting portion
- the bridge structure can be rotated relative to each other.
- the first support member includes a support surface and a cylindrical extension located below and fixedly coupled to the support surface;
- a top surface of the support seat that is in contact with the first support member has a groove that matches the cylindrical extension portion such that the cylindrical extension portion can be received in the groove by the groove Supported and able to rotate in the groove.
- the first support member includes a support surface and a cylindrical extension located below and fixedly coupled to the support surface, wherein the support surface extends beyond an upper surface of the cylindrical extension such that the support surface is from the columnar shape
- the side surface of the extension protrudes
- a top surface of the support seat that is in contact with the first support member has a groove matching the cylindrical extension portion such that the cylindrical extension portion can be received in the groove to receive the support surface
- the top surface is supported and enables the cylindrical extension to rotate in the groove.
- the first connecting portion is a jewel bearing, and the second connecting portion is a top cone;
- the first connecting portion is a top cone, and the second connecting portion is a jewel bearing;
- the jewel bearing is provided with a tapered groove
- the top cone is a tapered structure
- the tip end of the top cone is located in a tapered groove on the jewel bearing
- the top cone and the jewel bearing Connected in the form of point contacts.
- bracket of aspect 1 further comprising: at least one pair of magnets, wherein:
- a first magnet of the pair of magnets is fixed to a side of the first support portion adjacent to the second support portion, and a second magnet of the pair of magnets is fixed to the second support portion a side on the first support portion;
- the first magnet and the second magnet are stacked in parallel, and the two adjacent surfaces are isotropic magnetic poles.
- a stent of any one of aspects 1-9 wherein the lower end of the second support portion is coupled to one end of the rotating shaft to support the rotating shaft,
- the rotating shaft is enabled to rotate under the action of an external driving force.
- the thromboelastometer according to aspect 10 further comprising a measuring device, wherein the measuring device is configured to measure a rotation angle of the rotating shaft, and form a blood corresponding to the blood to be measured according to a rotation angle of the rotating shaft The thrombus stretch map.
- the measuring device comprises: a reflective sheet, a light emitting module, a light receiving module and a processing module;
- the rotating shaft is fixedly connected to the reflector, and the rotating shaft drives the reflector to rotate under the action of an external driving force;
- the light emitting module is configured to emit light from a fixed direction to the reflective sheet
- the reflective sheet is configured to receive light emitted by the light emitting module and reflect the received light
- the light receiving module is configured to receive light reflected by the retroreflective sheet from a fixed direction, convert the received light into a corresponding electrical signal according to the intensity of the light, and transmit the electrical signal to the processing module;
- the processing module is configured to process an electrical signal converted by the light receiving module to determine a rotation angle of the rotating shaft.
- the light emitting module includes a light emitting diode and a light guiding column, wherein the light emitting diode emits light to the reflective sheet through the light guiding column;
- the light receiving module includes a photocell and a light guiding column, wherein the photocell receives light emitted by the reflective sheet through the light guiding column.
- a support system comprising the bracket and the supported object according to any one of aspects 1-9, wherein a lower end of the second support portion is coupled to one end of the supported object to support the The support enables the supported object to rotate under external driving.
- the blood coagulation data of the blood to be measured is calculated based on the measured rotation angle of the rotation axis.
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Abstract
Description
Claims (15)
- 一种支架,包括:第一支撑部、第二支撑部和连接部,其中:所述第一支撑部通过所述连接部支撑所述第二支撑部,使得所述第二支撑部能够在第一作用力下相对于所述第一支撑部转动;所述第一支撑部包括:可转动结构、支撑座和止动机构,其中:所述止动机构用于提供对所述可转动结构的转动的阻止作用;所述可转动结构被支撑在所述支撑座上,并且在所述止动机构的所述阻止作用被消除的情况下能够在第二作用力下相对于所述支撑座转动;以及所述可转动结构通过所述连接部支撑所述第二支撑部,使得所述可转动结构在相对于所述支撑座转动时能够相对于所述第二支撑部转动。
- 根据权利要求1所述的支架,其中,所述可转动结构包括第一支撑件和桥式结构,其中:所述第一支撑件被支撑在所述支撑座上并且在所述止动机构的所述阻止作用被消除的情况下能够在所述第二作用力下相对于所述支撑座转动;所述桥式结构被支撑在所述第一支撑件上,并且与所述第一支撑件固定连接,使得当所述第一支撑件转动时所述桥式结构能够随着一起转动;以及所述桥式结构通过所述连接部支撑所述第二支撑部,使得当所述第一支撑件转动时所述桥式结构能够相对于所述第二支撑部转动。
- 根据权利要求1所述的支架,其中,所述止动机构选自以下各项中的一个或者是它们的任意组合:用于将所述可转动结构相对于所述支撑座固定的固定件;所述可转动结构与所述支撑座两者相互接触的具有预定粗糙度的表面;或在所述可转动结构与所述支撑座的接触表面之间提供可消除的粘滞力的材料。
- 根据权利要求2所述的支架,其中:所述第一支撑件的中心具有第一通孔,所述桥式结构跨过所述第一通孔固定到所述第一支撑件上;所述支撑座的中心具有与第一通孔至少部分地重合的第二通孔;所述第二支撑部的中心具有第三通孔;以及所述第二支撑部在被所述第一支撑部支撑时穿过所述第一通孔和所述第二通孔,并且所述桥式结构穿过所述第三通孔通过位于所述第三通孔内的所述连接部支撑所述第二支撑部。
- 根据权利要求2所述的支架,其中:所述连接部包括第一连接部和第二连接部;所述第一连接部与所述桥式结构固定连接,所述第二连接部与所述第二支撑部固定连接;以及所述第一连接部与所述第二连接部以点接触的方式连接在一起,使得所述第一连接部与所述第二连接部能够相对转动,从而使得所述第二支撑部与所述桥式结构能够相对转动。
- 根据权利要求2所述的支架,其中:所述第一支撑件包括支撑表面以及位于所述支撑表面下面并与其固定连接的柱状延伸部;以及所述支撑座的与所述第一支撑件相接触的顶表面上具有与所述柱状延伸部匹配的凹槽,使得所述柱状延伸部能够容纳在所述凹槽中受到所述凹槽的支撑并且能够在所述凹槽中转动。
- 根据权利要求2所述的支架,其中:所述第一支撑件包括支撑表面以及位于所述支撑表面下面并与其固定连接的柱状延伸部,其中所述支撑表面延伸超过所述柱状延伸部的上表面,使得所述支撑表面从所述柱状延伸部的侧表面突出出来;以及所述支撑座的与所述第一支撑件相接触的顶表面上具有与所述柱状延伸部匹配的凹槽,使得所述柱状延伸部能够容纳在所述凹槽中使所述支撑表面受到所述顶表面的支撑,并且使得所述柱状延伸部能够在所述凹槽中转动。
- 根据权利要求5所述的支架,其中:所述第一连接部为宝石轴承,所述第二连接部为顶锥;或者:所述第一连接部为顶锥,所述第二连接部为宝石轴承;其中,所述宝石轴承设置有锥形凹槽,所述顶锥为锥状结构,所述顶锥的尖端位于所述宝石轴承上的锥形凹槽内,所述顶锥与所述宝石轴承以点接触形式相连接。
- 根据权利要求1所述的支架,还包括:至少一对磁铁,其中:对于每一对磁铁,该对磁铁中的第一磁铁固定于所述第一支撑部上靠近所述第二支撑部的一侧,该对磁铁中的第二磁铁固定于所述第二支 撑部上靠近所述第一支撑部的一侧;以及所述第一磁铁与所述第二磁铁平行叠放,且相接近的两个面为同性磁极。
- 一种血栓弹力仪,包括如权利要求1-9中任一项所述的支架以及旋转轴,其中所述第二支撑部的下端与所述旋转轴的一端连接以支撑所述旋转轴,使得所述旋转轴能够在外部驱动力的作用下转动。
- 根据权利要求10所述的血栓弹力仪,还包括测量装置,其中所述测量装置用于对所述旋转轴的转动角度进行测量,并根据所述旋转轴的转动角度形成对应于被测血液的血栓弹力图。
- 根据权利要求11所述的血栓弹力仪,其中:所述测量装置包括:反光片、光发射模块、光接收模块及处理模块;所述旋转轴与所述反光片固定连接,所述旋转轴在外部驱动力作用下带动所述反光片转动;所述光发射模块用于从固定的方向向反光片发射光;所述反光片用于接收光发射模块发射的光,并对接收到的光进行反射;所述光接收模块,用于从固定的方向接收反光片反射的光,根据光的强度将接收到的光转换为对应的电信号,并将所述电信号传输给所述处理模块;所述处理模块,用于对所述光接收模块转换成的电信号进行处理,确定所述旋转轴的转动角度。
- 如权利要求12所述的血栓弹力仪,其中:所述光发射模块包括发光二极管及导光柱,其中,所述发光二极管通过所述导光柱向所述反光片发射光;和/或:所述光接收模块包括光电池及导光柱,其中,所述光电池通过所述导光柱接收所述反光片发射的光。
- 一种支撑系统,包括如权利要求1-9中任一项所述的支架以及被支撑物,其中所述第二支撑部的下端与所述被支撑物的一端相连接以支撑所述被支撑物,使得所述被支撑物能够在外部驱动作用下转动。
- 一种使用如权利要求10-13中任一项所述的血栓弹力仪的方法,包括:响应于所述第一支撑部所述第一支撑部相对于所述第二支撑部偏离 预定位置,消除所述止动机构的阻止作用;通过对所述第一支撑件施加所述第二作用力来使所述第一支撑件转动,从而使得所述桥式结构相对于所述第二支撑部转动至与所述第二支撑部形成预定角度的位置;使所述旋转轴的下端插入被测血液中;使所述被测血液旋转以带动所述旋转轴转动;以及基于所测量的所述旋转轴的转动角度来计算被测血液的血凝数据。
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US16/097,016 US11067490B2 (en) | 2016-04-29 | 2017-05-02 | Bracket, support system, and thrombelastography device and use method thereof |
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PCT/CN2017/082786 WO2017186190A1 (zh) | 2016-04-29 | 2017-05-02 | 支架、支撑系统、血栓弹力仪及其使用方法 |
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2017
- 2017-05-02 WO PCT/CN2017/082775 patent/WO2017186186A1/zh active Application Filing
- 2017-05-02 US US16/097,016 patent/US11067490B2/en active Active
- 2017-05-02 JP JP2019507986A patent/JP6964656B2/ja active Active
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US20190137377A1 (en) | 2019-05-09 |
WO2017186186A1 (zh) | 2017-11-02 |
US11067490B2 (en) | 2021-07-20 |
JP6964656B2 (ja) | 2021-11-10 |
JP2019515315A (ja) | 2019-06-06 |
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