WO2017111021A1 - Dispositif de formation de renfoncement, dispositif de distribution de médicament et dispositif d'emballage de médicament muni de celui-ci - Google Patents

Dispositif de formation de renfoncement, dispositif de distribution de médicament et dispositif d'emballage de médicament muni de celui-ci Download PDF

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Publication number
WO2017111021A1
WO2017111021A1 PCT/JP2016/088386 JP2016088386W WO2017111021A1 WO 2017111021 A1 WO2017111021 A1 WO 2017111021A1 JP 2016088386 W JP2016088386 W JP 2016088386W WO 2017111021 A1 WO2017111021 A1 WO 2017111021A1
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WO
WIPO (PCT)
Prior art keywords
recess
unit
medicine
prescription data
molding die
Prior art date
Application number
PCT/JP2016/088386
Other languages
English (en)
Japanese (ja)
Inventor
秀幸 菊池
佐藤 輝明
尚史 山林
Original Assignee
株式会社タカゾノテクノロジー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by 株式会社タカゾノテクノロジー filed Critical 株式会社タカゾノテクノロジー
Publication of WO2017111021A1 publication Critical patent/WO2017111021A1/fr

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B59/00Arrangements to enable machines to handle articles of different sizes, to produce packages of different sizes, to vary the contents of packages, to handle different types of packaging material, or to give access for cleaning or maintenance purposes
    • B65B59/003Arrangements to enable adjustments related to the packaging material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B47/00Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved
    • B65B47/02Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved with means for heating the material prior to forming
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B47/00Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved
    • B65B47/04Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved by application of mechanical pressure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B47/00Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved
    • B65B47/08Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved by application of fluid pressure
    • B65B47/10Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved by application of fluid pressure by vacuum
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B59/00Arrangements to enable machines to handle articles of different sizes, to produce packages of different sizes, to vary the contents of packages, to handle different types of packaging material, or to give access for cleaning or maintenance purposes
    • B65B59/001Arrangements to enable adjustments related to the product to be packaged
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/02Enclosing successive articles, or quantities of material between opposed webs
    • B65B9/04Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B2210/00Specific aspects of the packaging machine
    • B65B2210/04Customised on demand packaging by determining a specific characteristic, e.g. shape or height, of articles or material to be packaged and selecting, creating or adapting a packaging accordingly, e.g. making a carton starting from web material

Definitions

  • the present invention relates to, for example, a recess forming device used in a medicine packaging device capable of performing blister packaging, a medicine supply device provided with the same, and a medicine packaging device.
  • Patent Document 1 As a medicine packaging apparatus capable of performing blister packaging, for example, one described in Patent Document 1 can be cited.
  • the drug packaging apparatus described in Patent Document 1 is an apparatus that performs packaging by storing tablets in a tray having a storage recess formed in advance and attaching a lid sheet.
  • the tray used in the apparatus described in Patent Document 1 has, for example, a plurality of storage recesses whose capacity is set based on the size of the sheet used for forming the tray. For this reason, no consideration has been given to the relationship between the amount of medicine charged into each storage recess and the capacity of each storage recess. Therefore, for example, if there are many prescribed medicines, they may not be able to fit into each storage recess, and if there are few prescribed medicines, it may result in packaging with a lot of space. .
  • an object of the present invention is to provide a recess forming device suitable for appropriately packaging a prescribed medicine, a medicine supply device provided with the same, and a medicine packaging device.
  • a recess forming apparatus is a recess forming portion including a plurality of molds for forming a recess for containing a drug in a container film, each of the plurality of molds being A concave part forming part having different capacities of concave parts formed in the container film, a molding die switching part for switching a molding die used in the concave part forming part among the plurality of molding dies, and a prescription including information on prescription Based on the prescription data receiving unit that receives data and the prescription data received by the prescription data receiving unit, the molding die used in the recess forming unit is switched among the plurality of molding dies.
  • a control unit for controlling the switching unit.
  • the prescription data includes information on the amount of drug for a single dose, and the control unit relates to the amount of drug for a single dose in the prescription data received by the prescription data reception unit. Based on the information, the necessary capacity of the recess necessary for containing the medicine for one dose is derived, and the mold switching unit is controlled based on the derived necessary capacity.
  • the mold to be used can be switched to a mold according to the derived required capacity among the plurality of molds.
  • the prescription data includes information on prescriptions for multiple doses, and includes information on the amount of medicine for each dose, and the control unit receives the prescription data reception unit.
  • the largest necessary capacity is derived from each of the necessary capacity of the recesses necessary to accommodate the medicine for each dosage, and the most derived
  • the prescription data includes information on prescriptions for multiple doses, and includes information on the amount of medicine for each dose, and the control unit receives the prescription data reception unit. Based on the information about the amount of medicine for each dose in the prescription data, each of the necessary volumes of the recesses necessary to accommodate the medicine for each dose is derived, and based on each of the derived necessary volumes By controlling the molding die switching unit, the molding die used in the recess forming unit can be switched to a molding die corresponding to each of the derived required capacities in the plurality of molding dies. .
  • control part can also derive
  • medical agent supply apparatus which concerns on an example of the structure of this invention is equipped with the said recessed part formation apparatus and the chemical
  • medical agent packaging apparatus which concerns on an example of the structure of this invention packages a chemical
  • FIG. 1 It is a figure which shows the outline of a structure of a chemical
  • FIG. 1 It is a block diagram which shows the structure of the recessed part formation apparatus.
  • FIG. 1 It is a perspective view which shows the structural example (the 1) of the shaping
  • FIG. 2 It is a perspective view which shows the structural example (the 2) of the shaping
  • It is a flowchart which shows the operation
  • the drug packaging device 1 of the present embodiment is a device that forms a drug package P by automatically packaging the drug M using the packaging sheet 3 and the lid sheet 4.
  • the medicine packaging apparatus 1 includes a packaging sheet holding unit 11, a packaging sheet supply unit 12, a recess forming unit 13, a drug supply unit 14, a drug feeding unit 15, a lid sheet holding unit 16, a lid.
  • a sheet supply unit 17, a lid sheet bonding unit 18, a cutting unit 19, and a printing unit 20 are provided. Each unit is controlled by the control unit 5.
  • the packaging sheet holding unit 11 holds a flat packaging sheet (container film) 3.
  • the packaging sheet 3 is a resin sheet.
  • As the packaging sheet 3 of the present embodiment for example, a thermoplastic resin sheet is used.
  • the packaging sheet 3 has a long band shape, and is held in a wrapping roll-like body 3 a so as to be drawable by the packaging sheet holding unit 11.
  • the dimension in the width direction of the packaging sheet 3 is a dimension that allows one recess 31 to be formed.
  • the flat packaging sheet 3 is not limited to a long belt shape, but is a rectangular shape in plan view (short), and is configured such that a plurality of packaging sheets 3 are stacked on the packaging sheet holding portion 11. You can also Moreover, the packaging sheet 3 of this embodiment is transparent. For this reason, it is easy to visually recognize the medicine M stored in the recess 31 in the state after packaging. In the present embodiment, a transparent packaging sheet 3 is used, but the packaging sheet 3 is not necessarily transparent.
  • the packaging sheet 3 may be translucent or opaque, for
  • the packaging sheet 3 in a rolled state can be held by the packaging sheet holding unit 11.
  • the packaging sheet 3 having a rectangular shape in plan view can be configured to be stacked and held on the packaging sheet holding unit 11. That is, the packaging sheet holding part 11 can hold the packaging sheet 3 in an amount sufficient to form a large number of medicine packaging bodies P at a time. For this reason, it is not necessary to set the trays having the storage recesses one by one as in the prior art. For this reason, the operator of the medicine packaging apparatus is freed from complicated work.
  • the “flat” includes a form in which irregularities and patterns that do not hinder the formation of the concave portion 31 by the concave portion forming portion 13 described later are formed.
  • the packaging sheet supply unit 12 takes out the packaging sheet 3 from the packaging sheet holding unit 11 and supplies it in the longitudinal direction.
  • the packaging sheet 3 is supplied while the tension is adjusted by a plurality of rollers 121... 121 as shown. Since a driving force is transmitted to some rollers (not shown) provided immediately upstream of the below-described cutting portion 19, the packaging sheet 3 is pulled. For this reason, the packaging sheet 3 is taken out from the packaging sheet holding unit 11.
  • the supply of the packaging sheet 3 is stopped when the recess 31 is formed in the packaging sheet 3 by a molding die 133 described later. For this reason, the supply is made intermittently. Since the packaging sheet supply unit 12 can automatically form the packaging sheet 3 that is supplied and then the medicine M can be charged, the packaging sheet can be easily packaged.
  • the means for taking out the packaging sheet 3 is not limited to a roller.
  • a means for taking out the packaging sheet 3 for example, a means for sandwiching and pulling the packaging sheet 3 may be employed. Further, as this means, various means such as an arm and a rubber plate can be adopted.
  • the packaging sheet supply unit 12 is configured so that the packaging sheet 3 can be taken out from the packaging sheet holding unit 11 one by one.
  • the recess forming part 13 constitutes a part of the recess forming apparatus X and forms a plurality of recesses 31... 31 at predetermined intervals in the longitudinal direction on the packaging sheet 3 supplied by the packaging sheet supply part 12. To do.
  • the formed recesses 31 can contain the medicine M.
  • the recess forming part 13 includes a hot plate 131, a receiving part 132, and a molding die 133.
  • a plurality of molding dies 133... 133 having at least different shapes of the female dies 133 a are provided so that the concave portions 31 having different capacities can be formed by the respective molding dies 133. Details of the recess forming device X will be described later.
  • the hot plate 131 and the receiving portion 132 are opposed to each other with the conveyed packaging sheet 3 interposed therebetween. Each surface where the hot plate 131 and the receiving portion 132 face each other is a flat surface. With respect to the packaging sheet 3, the hot plate 131 is positioned below and the receiving portion 132 is positioned above. The arrangement of the hot plate 131 and the receiving part 132 with respect to the packaging sheet 3 may be reversed.
  • the heat plate 131 has a built-in heater.
  • the receiving part 132 is made of resin.
  • the receiving part 132 of this embodiment is made of rubber. The hot plate 131 and the receiving portion 132 can be moved toward and away from the packaging sheet 3 by being driven by an electric motor.
  • the drive source for driving the heat plate 131 and the receiving part 132 is not limited to the electric motor.
  • the drive source of the hot plate 131 and the receiving portion 132 may be any as long as the hot plate 131 and the receiving portion 132 can be moved toward and away from the packaging sheet 3.
  • the drive source of the hot plate 131 and the receiving part 132 may be, for example, an air cylinder or a hydraulic cylinder. In a state where the heater is energized and the hot plate 131 is heated, the hot plate 131 and the receiving part 132 approach so as to sandwich the packaging sheet 3, whereby the packaging sheet 3 can be softened.
  • the hot plate 131 and the receiving portion 132 are formed to have a size of two packages (two concave portions 31) in the longitudinal direction.
  • the packaging sheet 3 moves intermittently so that the concave portion 31 is formed for every single package (one concave portion 31) by the molding die 133. With this intermittent movement, the packaging sheet 3 is heated twice and then supplied to the mold 133. For this reason, since the first heating is “preliminary heating” and the second heating is “main heating”, the packaging sheet 3 can be sufficiently softened due to the formation of the recess 31.
  • the hot plate 131 and the receiving part 132 are not necessarily formed to have a size of two packages (two concave parts 31) in the longitudinal direction.
  • the hot plate 131 and the receiving portion 132 may be formed in a size of one package (one recess 31) in the longitudinal direction. If the packaging sheet 3 is not sufficiently softened even by two heatings, the hot plate 131 and the receiving portion 132 may be formed in a size of three packages (three concave portions 31) or more in the longitudinal direction. .
  • the forming die 133 is located downstream of the hot plate 131 and the receiving portion 132 in the sheet conveying direction.
  • the molding die 133 includes a female die 133a positioned below the packaging sheet 3 to be conveyed, a male die 133b positioned above, and a pressing plate 133c.
  • the female mold 133a and the male mold 133b have a shape corresponding to the recess 31 so that the recess 31 having a desired diameter and size can be formed.
  • the concave portion 31 formed in the present embodiment has a circular cross-sectional shape, and has a shape in which the diameter dimension decreases as it goes downward as illustrated.
  • a plurality of suction holes are formed on the concave molding surface of the female die 133a.
  • the female mold 133a, the male mold 133b, and the presser plate 133c can be moved toward and away from the packaging sheet 3.
  • the female mold 133a, the male mold 133b, and the pressing plate 133c are driven by an electric motor so that the packaging sheet 3 can be approached and separated.
  • the drive source for driving the female mold 133a, the male mold 133b, and the presser plate 133c is not limited to the electric motor.
  • the driving source of the female mold 133a, the male mold 133b, and the presser plate 133c may be any as long as the female mold 133a, the male mold 133b, and the presser plate 133c can be moved toward and away from the packaging sheet 3.
  • the drive source of the female mold 133a, the male mold 133b, and the presser plate 133c may be, for example, an air cylinder or a hydraulic cylinder.
  • the male mold 133b and the holding plate 133c approach the female mold 133a so as to sandwich the packaging sheet 3 softened by the hot plate 131. While the packaging sheet 3 is sandwiched between the female mold 133a and the presser plate 133c, air is sucked from the plurality of suction holes, whereby a recess 31 that is recessed downward is formed in the packaging sheet 3. In this state, the concave part 31 having a desired shape is reliably formed by further fitting the male mold 133b to the female mold 133a.
  • the male mold 133b is not necessarily provided.
  • the male mold 133b may be omitted if the concave portion 31 having a desired shape can be formed by sucking air from the plurality of suction holes of the female mold 133a.
  • one set of the molding die 133 of the present embodiment is provided, and is configured to form one recess 31 at a time (one cycle of vertical movement of the female die 133a and the male die 133b).
  • a plurality of sets of molding dies 133 in parallel along the longitudinal direction of the packaging sheet 3 or in the width direction of the packaging sheet 3 (front and back direction in FIG. 1), a plurality of recesses 31. 31 can also be formed.
  • the drug supply unit 14 temporarily stores the drug M. Then, the medicine supply unit 14 supplies the medicine M to the medicine input unit 15 according to prescription data that is data including information on prescription (for example, for each dose). Thereby, the medicine M is supplied to the concave portion 31 formed in the packaging sheet 3 by the concave portion forming portion 13.
  • the drug supply unit 14 includes a storage unit 141 that temporarily stores the drug M.
  • the drug supply unit 14 can selectively supply the drug M from the storage unit 141 under the control of the control unit 5.
  • the storage unit 141 for tablets there can be exemplified a storage cassette and each recess in a distribution basket in which a plurality of recesses are arranged in a matrix.
  • the storage unit 141 is for powders, for example, a saddle with a V-shaped concave section and a powder distribution device formed in a disc shape and configured to scrape powder according to prescription data. it can.
  • the medicine supply unit 14 is not limited to these exemplified forms and can be implemented in various forms.
  • the storage unit 141 can be configured by, for example, a plurality of storage units for each type that store the medicine M for each type, or a plurality of storage units for each dose that stores the drug M for each dose. It is.
  • the medicine supply unit 14 can store the medicine M for each type or for each dose in a state suitable for supplying the medicine M.
  • the medicine M can be easily replenished.
  • the medicine M when the medicine M is stored for each dose by the dose storage unit, it can be supplied to the drug input unit 15 in the stored state.
  • the drug supply unit 14 of the present embodiment can handle drugs of various dosage forms. For example, a tablet, a capsule, and a powder are mentioned. Further, in the present embodiment, it is configured to handle only a solid drug, but depending on the case, it is also possible to handle a liquid or gel drug.
  • the drug injection unit 15 inputs the drug M into each recess 31 formed in the packaging sheet 3 by the recess forming unit 13.
  • the medicine charging unit 15 of the present embodiment is configured as a hopper having an upward shape, and is positioned below the medicine supply unit 14.
  • the medicine feeding section 15 is formed in a shape suitable for dispensing such as a nozzle shape.
  • the lid sheet holding unit 16 holds the flat lid sheet 4.
  • a resin sheet is used as the lid sheet 4 of the present embodiment.
  • the lid sheet 4 has a strip shape.
  • the lid sheet 4 is held in such a manner that it can be pulled out to the lid sheet holding portion 16 in the state of a rolled roll 4a.
  • the lid sheet 4 has a width that can cover the opening of the recess 31 formed in the packaging sheet 3.
  • the width of the lid sheet 4 of the present embodiment is the same as the width of the packaging sheet 3.
  • paper or paper coated with resin can be used as the cover sheet 4.
  • the lid sheet supply unit 17 applies the lid sheet 4 for closing the opening of the concave portion 31 to the packaging sheet 3 in the state where the concave portions 31... To supply.
  • the lid sheet supply unit 17 supplies the lid sheet 4 to the upper surface of the packaging sheet 3.
  • the lid sheet supply unit 17 supplies the lid sheet 4 to the packaging sheet 3 from above.
  • the lid sheet supply unit 17 may supply the lid sheet 4 to the packaging sheet 3 from the side or from below.
  • the lid sheet supply unit 17 takes out the lid sheet 4 from the lid sheet holding unit 16 and supplies it in the longitudinal direction.
  • the lid sheet 4 is supplied while the tension is adjusted by a plurality of rollers 171.
  • the lid sheet 4 Since the driving force is transmitted to some rollers (not shown) provided at the closest position on the upstream side of the cutting portion 19 described later, the lid sheet 4 is pulled. For this reason, the lid sheet 4 is taken out from the lid sheet holding part 16.
  • the packaging sheet 3 and the lid sheet 4 are pulled by a common roller.
  • the supply is stopped when the lid sheet 4 is bonded to the packaging sheet 3 by the lid sheet bonding portion 18 described later. For this reason, the supply is made intermittently.
  • the intermittent supply of the lid sheet 4 is synchronized with the supply of the packaging sheet 3.
  • the means for taking out the lid sheet 4 is not limited to a roller.
  • a means for taking out the lid sheet 4 for example, a means for sandwiching and pulling the lid sheet 4 may be employed. Further, as this means, various means such as an arm and a rubber plate can be adopted.
  • the lid sheet bonding unit 18 bonds the lid sheet 4 supplied by the lid sheet supply unit 17 to the packaging sheet 3 in a state where the lid sheet 4 is closed by covering the opening of the recess 31.
  • the lid sheet bonding part 18 includes a hot plate 181 and a receiving part 182.
  • the hot plate 181 and the receiving portion 182 are opposed to each other with the lid sheet 4 to be conveyed and the portion of the packaging sheet 3 where the concave portion 31 is not formed interposed therebetween.
  • Each surface where the heat plate 181 and the receiving portion 182 face each other is a flat surface.
  • the heat plate 181 is located above and the receiving portion 182 is located below.
  • the heating plate 181 has a built-in heater.
  • the receiving part 182 is made of resin.
  • the receiving portion 182 of this embodiment is made of rubber.
  • the receiving portion 182 may be another hot plate in which a heater is built.
  • the hot plate 181 and the receiving portion 182 can be moved toward and away from the lid sheet 4 and the packaging sheet 3 by being driven by an electric motor.
  • the drive source for driving the heat plate 181 and the receiving part 182 is not limited to the electric motor.
  • the drive source of the hot plate 181 and the receiving portion 182 may be any drive source that can move the hot plate 181 and the receiving portion 182 toward and away from the lid sheet 4 and the packaging sheet 3.
  • the drive source of the hot plate 181 and the receiving part 182 may be, for example, an air cylinder or a hydraulic cylinder.
  • the receiving portion 182 is formed with a recess into which the recessed portion 31 is fitted so that the receiving portion 182 and the recessed portion 31 do not interfere with each other.
  • a circular hole passes through the center of the receiving portion 182 as a recess so that it does not interfere with the concave portion 31 when the receiving portion 182 moves upward.
  • the cutting unit 19 cuts the packaging sheet 3 to which the lid sheet 4 is bonded together with the sheets 3 and 4 together for one or more doses.
  • the cutting unit 19 of the present embodiment includes cutting blades 191 and 191 that are positioned above and below the packaging sheet 3 and are movable so that the blade edges overlap. Thereby, the medicine package P is separated into units that are easy for the patient to take. Accordingly, it is possible to obtain a medicine package P that is grouped in one or more dose units.
  • a perforation can be formed in the packaging sheet 3 and the lid sheet 4 by changing the shape of the cutting blade 191.
  • the medicine package P can be appropriately cut according to the convenience of the patient, so that the patient's convenience is improved when taking or storing the medicine package P.
  • the printing unit 20 prints information corresponding to the prescription data on the lid sheet 4. Since the printing unit 20 can perform printing in a series of steps, it is possible to easily form the medicine package P up to a state where it can be delivered to the patient. Examples of the printed contents include the patient's name, the date of taking, the day of the week, and the timing of taking (after meal, before meal, between meals, etc.). In this embodiment, printing is performed on the lid sheet 4 before being bonded to the packaging sheet 3. For this reason, the printing part 20 is located above the conveyance line of the packaging sheet 3. Note that printing can also be performed on the lid sheet 4 after being bonded to the packaging sheet 3. Examples of the printing method include a method of thermal transfer using an ink ribbon, but various methods such as an ink jet method can be adopted.
  • the recess forming device X will be described below. As shown in FIG. 2 (block diagram), the recess forming device X of the present embodiment includes the above-described recess forming unit 13, a mold switching unit 21, a prescription data receiving unit 22, and a recess forming control unit (invoice). “Control unit”) 23 described in the range.
  • Each of the plurality of molds 133... 133 provided in the recess forming part 13 has different capacities (volumes in this embodiment) of the recesses 31... 31 formed in the packaging sheet 3. For this reason, in the plurality of molds 133... 133, at least the female mold 133a (particularly, the mold recesses 133a1 to 133a3 that are the recesses of the female mold 133a that deform the packaging sheet 3) have different shapes.
  • the different capacities of the recesses 31... 31 can be realized by a plurality of molds 133... 133 in which the cross-sectional dimensions and depth dimensions of the mold recesses 133a1 to 133a3 in the female mold 133a are proportional. Further, the ratio of the cross-sectional dimension and the depth dimension of the mold recess in the female mold 133a is changed (for example, only the cross-sectional dimension is changed or only the depth dimension is changed). 133 can also be realized. Further, it can also be realized by a plurality of molding dies 133... 133 that have different cross-sectional shapes of the mold recesses in the female mold 133a (for example, a circular cross-sectional shape and a quadrangular cross-sectional shape exist). In this way, different capacities can be realized by various patterns of the plurality of molds 133.
  • the molding die switching unit 21 switches the molding die 133 used in the recess forming unit 13 among the plurality of molding dies 133. This switching is performed so that the molding die 133 selected from the plurality of molding dies 133... Note that the number of molds 133 selected at a time in the present embodiment is one, but is not limited to this. For example, when the recess forming portion 13 is configured to simultaneously form a plurality of recesses 31... 31. Can also select two or more molds 133 at a time.
  • the prescription data receiving unit 22 receives prescription data input to the medicine packaging device 1 (particularly the recess forming device X).
  • the prescription data may be input manually by a user such as a pharmacist or may be automatically performed by an input device connected to the drug packaging device 1 (recess forming device X).
  • the concave portion forming control unit 23 controls the molding die switching unit 21 to switch the molding die 133 used in the concave portion forming unit 13 based on the prescription data received by the prescription data receiving unit 22.
  • the recess forming control unit 23 can be provided in the control unit 5 of the medicine packaging device 1, or can be used independently (in addition to the control unit 5) to control the recess forming device X. ) Can also be provided.
  • FIGS. 3 to 6 illustrate the configuration of the molding die switching unit 21.
  • FIG. 3 to 5 uses a mold assembly 133u integrated with at least the female mold 133a, and the configuration example shown in FIG. 6 includes a plurality of molding dies 133 ... 133 (female molds). 133a... 133a) are used individually.
  • the molding die assembly 133u includes a female die 133a having a plurality of (three in this configuration example) mold recesses 133a1 to 133a3 having different sizes.
  • the female mold 133a has a rectangular shape in plan view, and the mold recesses 133a1 to 133a3 are arranged in the longitudinal direction.
  • On the lower side surface of the female die 133a there is provided a die moving rack 211 that is a gear that is linear in the longitudinal direction.
  • a mold moving motor 212 is provided for rotating a drive-side pinion 212a (tooth is not shown) positioned so as to mesh with the teeth of the mold moving rack 211.
  • the female mold 133a By rotating the mold moving motor 212, the female mold 133a can be moved in the longitudinal direction (the arrow direction in the figure).
  • the male mold 133b (if provided) and the holding plate 133c are also shaped to correspond to the mold recesses 133a1 to 133a3, and are configured to move in parallel with the movement of the female mold 133a. Has been.
  • the configuration example shown in FIG. 4 is common to the configuration example shown in FIG. 3 in that the female die 133a having a rectangular shape in plan view can be moved in the longitudinal direction with respect to the mold assembly 133u.
  • this configuration example is different in that a die moving cylinder 213 is connected to the longitudinal end of the female die 133a. By expanding and contracting the mold moving cylinder 213, the female mold 133a can be moved in the longitudinal direction (the direction of the arrow in the figure).
  • the mold assembly 133u includes a hexagonal column-shaped female mold 133a having a plurality of mold recesses 133a1 to 133a3 of different sizes, one on each outer peripheral surface. .
  • a mold moving gear 214 is provided on one end face of the female mold 133a.
  • a mold moving motor 215 that rotates a driving gear 215a (tooth not shown) positioned so as to mesh with the teeth of the mold moving gear 214 is provided. By rotating the mold moving motor 215, the female mold 133a can be moved in the circumferential direction (arrow direction in the figure).
  • the male mold 133b (if provided) and the holding plate 133c in this configuration are also shaped to correspond to the mold recesses 133a1 to 133a3, and are configured to move relative to the female mold 133a. Has been.
  • a plurality of female molds 133 a... 133 a each having a mold recess having a different size are stored in the storage unit 216, for example, on the mold table 218 using the robot arm 217. Can be replaced.
  • the configuration of the molding die switching unit 21 is not limited to the above examples, and various configurations can be adopted.
  • the recess forming apparatus X configured as described above, since the molding die 133 is switched from the plurality of molding dies 133... 133 according to the prescription data, it is possible to form the recesses 31 having an appropriate capacity.
  • the prescription data may include information on the amount of drug for a single dose.
  • the concave portion forming control unit 23 is necessary for accommodating the medicine M for a single dose based on the information regarding the amount of the medicine for a single dose in the prescription data received by the prescription data receiving unit 22. Necessary capacity of the concave portion 31 is derived.
  • the concave portion forming control unit 23 controls the molding die switching unit 21 based on the derived necessary capacity, so that the molding die 133 used in the concave portion forming unit 13 is changed to the molding die 133 corresponding to the derived necessary capacity. Switching is possible.
  • the “derivation” in this embodiment includes not only calculation by calculation but also derivation by referring to a table previously stored in the recess formation control unit 23 and the like, and allows various procedures.
  • the required capacity can be derived in consideration of a predetermined margin rate.
  • the prescription data includes information on the amount of drug for a single dose
  • the required volume is derived based on the information on the amount of drug for a single dose in the prescription data
  • the mold 133 can be switched.
  • capacitance can be formed according to the chemical
  • the concave portion formation control unit 23 of the present embodiment derives the necessary volume of the concave portion 31 formed by the concave portion forming portion 13 as the necessary capacity.
  • the required volume takes into account, for example, the volume of the drug M (the volume of the solid part) and the volume of the gap (the volume of the space part) that is expected to be formed around the drug M in the state of being inserted into the recess 31.
  • the derivation is performed in accordance with, for example, a combination of medicines M in a single dose.
  • the prescription data includes information on prescriptions for a plurality of doses, and can also include information on the amount of drug for each dose.
  • the recess formation control unit 23 derives the largest necessary capacity among the necessary capacity for the medicine M for each dose based on the information regarding the medicine amount for each dose.
  • the concave portion forming control unit 23 controls the molding die switching unit 21 based on the derived maximum required capacity. In this case, since the molding die 133 can be switched on a prescription basis, it is not necessary to frequently switch the molding die 133. For this reason, operation
  • the recess formation control unit 23 provides information on the drug amount for each dose. Based on the above, it is also possible to derive each of the necessary volumes for the medicine M for each dose, and to control the mold switching unit 21 based on each of the derived necessary volumes. In this case, since the molding die 133 can be switched on a dosing basis, a fine response can be made without causing waste in forming the recess 31.
  • the recess forming device X of the present embodiment can be combined with the drug supply unit 14 to constitute a drug supply device.
  • the medicine supply device configured as described above can successively perform the formation of the recess 31 on the packaging sheet 3 and the supply of the medicine M to the formed recess 31.
  • the recess forming device X of the present embodiment is combined with a medicine packaging unit for packaging the medicine M by sealing the recess 31 in a state where the medicine M is accommodated in the recess 31 formed by the recess forming device X.
  • the medicine packaging device 1 can be configured.
  • the medicine packaging unit includes the lid sheet holding unit 16, the lid sheet supply unit 17, and the lid sheet bonding unit 18 described above. This medicine packaging apparatus 1 can perform a series of formation of the recess 31 in the packaging sheet 3 and sealing with the medicine M accommodated in the formed recess 31.
  • FIG. 7 shows an operation flow of the molding die switching unit 21 mainly including the concave portion forming control unit 23.
  • three molding dies (first to third molding dies) are used as the molding die 133, and the second molding die has a larger volume in the packaging sheet 3 than the first molding die. 31 can be formed, and the third molding die can form the concave portion 31 having a larger volume in the packaging sheet 3 than the second molding die.
  • the first to third molds include a case where a mold assembly 133u integrated with at least the female mold 133a is used.
  • the required volume is derived (step S1).
  • step S2 it is determined whether the required volume is smaller than the first mold (the volume of the recess 31 formed by the mold) (step S2). If YES (“YES” in FIG. 7, the same applies hereinafter), it is determined whether or not the mold 133 disposed in the recess forming portion 13 at that time is other than the first mold (step). S3). If yes (if other than the first mold), the mold switching unit 21 is controlled to place the first mold in the recess forming part 13 (step S4).
  • step S2 it is determined whether the required volume is smaller than the second mold (the volume of the recess 31 formed by the second mold) (step S2). S5). If YES, it is determined whether or not the molding die 133 disposed in the recess forming portion 13 at that time is other than the second molding die (step S6). If yes (if other than the second mold), the mold switching unit 21 is controlled to place the second mold in the recess forming part 13 (step S7).
  • step S5 it is determined whether or not the required volume is smaller than the third mold (the volume of the recess 31 formed thereby) (step S8). If yes, it is determined whether or not the molding die 133 disposed in the recess forming portion 13 at that time is other than the third molding die (step S9). If yes (if other than the third mold), the mold switching unit 21 is controlled to place the third mold in the recess forming part 13 (step S10).
  • Step S11 the recess 31 is formed in the packaging sheet 3 by the first to third molds arranged, and packaging processing is performed (Step S11). If the answer is NO in steps S3, S6, and S9, the process proceeds to step S11. If NO in step S8, an error notification is given to the user (step S12).
  • the medicine packaging device 1 including the recess forming device X of the present embodiment configured as described above, the supply of the packaging sheet, the formation of the plurality of recesses 31. Can do. Therefore, blister packaging can be easily performed.
  • the concave portion forming apparatus X is a concave portion forming portion 13 including a plurality of molds 133 for forming the concave portion 31 for accommodating the medicine M in the packaging sheet (container film) 3.
  • the plurality of molds 133 are used in the recess forming part 13 and the recess forming part 13 out of the plurality of forming molds 133, each having a different capacity of the recess 31 formed in the packaging sheet (container film) 3.
  • the concave part forming unit 21 Based on the prescription data received by the prescription data receiving unit 22, the concave part forming unit 21, a mold switching unit 21 that switches to the mold 133 to be performed, a prescription data receiving unit 22 that receives prescription data including information related to prescription A control unit 5 for controlling the molding die switching unit 21 so as to switch the molding die 133 used in the molding die 133 among the plurality of molding dies 133.
  • the concave portion 31 having an appropriate capacity can be formed in the packaging sheet (container film) 3.
  • the prescription data includes information on the amount of medicine for a single dose
  • the control unit 5 includes a medicine for a single dose in the prescription data received by the prescription data reception unit 22.
  • the necessary capacity of the recess 31 necessary for storing the medicine for one dose is derived, and by controlling the molding die switching unit 21 based on the derived necessary capacity,
  • the molding die 133 used in the recess forming portion 13 can be switched to a molding die corresponding to the derived required capacity among the plurality of molding dies 133.
  • capacitance of the recessed part 31 required in order to accommodate the medicine for a single dose is derived
  • led-out the required capacity
  • the prescription data includes information on prescriptions for multiple doses and information on the amount of medicine for each dose, and the control unit 5 receives the prescription data reception unit 22. Further, in the prescription data, based on the information about the amount of medicine for each dose, the largest necessary capacity is derived among the necessary capacity of the recess 31 necessary to accommodate each dose of medicine, By controlling the molding die switching unit 21 on the basis of the derived maximum required capacity, the molding die 133 used in the concave portion forming unit 13 is the most necessary requirement derived among the plurality of molding die 133. It can be switched to a mold according to the capacity.
  • the prescription data includes information on prescriptions for multiple doses and information on the amount of medicine for each dose, and the control unit 5 receives the prescription data reception unit 22.
  • each of the necessary capacity of the recess 31 required to accommodate the medicine for each dose is derived, and each of the derived necessary capacity is Based on the control of the molding die switching unit 21, the molding die 133 used in the recess forming unit 13 is changed to a molding die corresponding to each of the derived required capacities in the plurality of molding dies 133. It can be switched.
  • control part 5 can also derive
  • the required capacity can be easily derived by using the required volume.
  • medical agent supply apparatus which concerns on an example of the structure of this invention is equipped with the said recessed part formation apparatus X and the chemical
  • the formation of the recess 31 on the packaging sheet (container film) 3 and the supply of the medicine M to the formed recess 31 can be performed in series.
  • the medicine packaging device 1 includes the concave portion 31 in a state where the medicine M is accommodated in the concave portion forming device X and the concave portion 31 formed by the concave portion forming device X. By sealing, a medicine packaging part for packaging medicine M is provided.
  • the molding die 133 since the molding die 133 is switched according to the prescription data, the concave portion 31 having an appropriate capacity can be formed. For this reason, the recessed part formation apparatus X suitable for performing appropriate packaging with respect to the prescribed chemical

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  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Fluid Mechanics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)
  • Basic Packing Technique (AREA)

Abstract

La présente invention concerne un dispositif de formation d'un renfoncement muni : d'une unité de formation de renfoncement (13) qui est pourvue d'une pluralité de filières de formation qui forment des renfoncements pour loger un médicament dans un film formant contenant, les capacités des renfoncements formés dans le film formant contenant par chacune de la pluralité des filières de formation étant différentes les unes des autres ; une unité de commutation de filière de formation (21) qui commute la filière de formation utilisée dans l'unité de formation de renfoncement (13) entre la pluralité de filières de formation ; une unité de réception de données d'ordonnance (22) qui reçoit les données d'ordonnance comprenant l'information se rapportant à une ordonnance ; une unité de commande (23) qui commande l'unité de commutation de filière de formation (21) afin de commuter la filière de formation utilisée dans l'unité de formation de renfoncement (13) entre la pluralité de filières de formation, sur la base des données d'ordonnance reçues par l'unité de réception de données d'ordonnance (22).
PCT/JP2016/088386 2015-12-24 2016-12-22 Dispositif de formation de renfoncement, dispositif de distribution de médicament et dispositif d'emballage de médicament muni de celui-ci WO2017111021A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015251698A JP2017113270A (ja) 2015-12-24 2015-12-24 凹部形成装置及びこれを備えた薬剤供給装置、薬剤包装装置
JP2015-251698 2015-12-24

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JP (1) JP2017113270A (fr)
TW (1) TW201730051A (fr)
WO (1) WO2017111021A1 (fr)

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Publication number Priority date Publication date Assignee Title
IT202000019414A1 (it) * 2020-08-06 2022-02-06 Tecno Pack S P A Macchina confezionatrice orizzontale con gruppo taglia-cuci regolabile

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751805A (en) * 1986-02-24 1988-06-21 Hassia Verpackungsmaschinen Gmbh Packing machine
JPH09202301A (ja) * 1996-01-25 1997-08-05 Yuyama Seisakusho:Kk 薬剤分包方法と検薬方法
JP2000185703A (ja) * 1998-12-21 2000-07-04 Tooshoo:Kk 薬剤分包機
JP2013220832A (ja) * 2012-04-16 2013-10-28 Sumitomo Bakelite Co Ltd 薬剤包装体製造装置および薬剤包装体

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751805A (en) * 1986-02-24 1988-06-21 Hassia Verpackungsmaschinen Gmbh Packing machine
JPH09202301A (ja) * 1996-01-25 1997-08-05 Yuyama Seisakusho:Kk 薬剤分包方法と検薬方法
JP2000185703A (ja) * 1998-12-21 2000-07-04 Tooshoo:Kk 薬剤分包機
JP2013220832A (ja) * 2012-04-16 2013-10-28 Sumitomo Bakelite Co Ltd 薬剤包装体製造装置および薬剤包装体

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TW201730051A (zh) 2017-09-01
JP2017113270A (ja) 2017-06-29

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