WO2017111026A1 - Dispositif de formage d'évidement, et dispositif de distribution de médicament et dispositif de conditionnement de médicament équipé de celui-ci - Google Patents

Dispositif de formage d'évidement, et dispositif de distribution de médicament et dispositif de conditionnement de médicament équipé de celui-ci Download PDF

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Publication number
WO2017111026A1
WO2017111026A1 PCT/JP2016/088391 JP2016088391W WO2017111026A1 WO 2017111026 A1 WO2017111026 A1 WO 2017111026A1 JP 2016088391 W JP2016088391 W JP 2016088391W WO 2017111026 A1 WO2017111026 A1 WO 2017111026A1
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WO
WIPO (PCT)
Prior art keywords
recess
capacity
unit
medicine
prescription data
Prior art date
Application number
PCT/JP2016/088391
Other languages
English (en)
Japanese (ja)
Inventor
秀幸 菊池
佐藤　輝明
尚史 山林
Original Assignee
株式会社タカゾノテクノロジー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社タカゾノテクノロジー filed Critical 株式会社タカゾノテクノロジー
Publication of WO2017111026A1 publication Critical patent/WO2017111026A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B59/00—Arrangements to enable machines to handle articles of different sizes, to produce packages of different sizes, to vary the contents of packages, to handle different types of packaging material, or to give access for cleaning or maintenance purposes
    • B65B59/003—Arrangements to enable adjustments related to the packaging material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B47/00—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved
    • B65B47/02—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved with means for heating the material prior to forming
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B47/00—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved
    • B65B47/04—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved by application of mechanical pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B47/00—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved
    • B65B47/08—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved by application of fluid pressure
    • B65B47/10—Apparatus or devices for forming pockets or receptacles in or from sheets, blanks, or webs, comprising essentially a die into which the material is pressed or a folding die through which the material is moved by application of fluid pressure by vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B59/00—Arrangements to enable machines to handle articles of different sizes, to produce packages of different sizes, to vary the contents of packages, to handle different types of packaging material, or to give access for cleaning or maintenance purposes
    • B65B59/001—Arrangements to enable adjustments related to the product to be packaged
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/02—Enclosing successive articles, or quantities of material between opposed webs
    • B65B9/04—Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B2210/00—Specific aspects of the packaging machine
    • B65B2210/04—Customised on demand packaging by determining a specific characteristic, e.g. shape or height, of articles or material to be packaged and selecting, creating or adapting a packaging accordingly, e.g. making a carton starting from web material

Definitions

  • the present invention relates to, for example, a recess forming device used in a medicine packaging device capable of performing blister packaging, a medicine supply device provided with the same, and a medicine packaging device.
  • Patent Document 1 As a medicine packaging apparatus capable of performing blister packaging, for example, one described in Patent Document 1 can be cited.
  • the drug packaging apparatus described in Patent Document 1 is an apparatus that performs packaging by storing tablets in a tray having a storage recess formed in advance and attaching a lid sheet.
  • Patent Document 1 uses a sheet in which a plurality of concave portions having a certain capacity are formed, and performs packaging so that a single dose of medicine is accommodated in one concave portion. For this reason, for example, if there are many prescribed medicines, they may not be able to fit into the recesses.
  • an object of the present invention is to provide a recess forming device suitable for appropriately packaging a prescribed medicine, a medicine supply device provided with the same, and a medicine packaging device.
  • a recess forming apparatus uses a mold to form a recess for accommodating a drug in a container film, and a prescription for receiving prescription data including prescription information.
  • a mold In receiving the medicine for a single dose in the concave portion formed in the container film by the data receiving portion and the concave portion forming portion, whether the capacity of the concave portion is insufficient is received by the prescription data receiving portion.
  • a determination unit that makes a determination based on prescription data, a notification unit for notifying the lack of capacity of the recess, and a recess formed in the container film when the determination unit determines that the capacity of the recess is not insufficient
  • the concave portion forming portion is controlled so that when the determination portion determines that the capacity of the concave portion is insufficient, the user is notified of the shortage of the concave portion.
  • the said recessed part formation apparatus is further provided with the selection result reception part which receives the selection result of continuing the formation of the recessed part to the film for containers, or canceling, and the said control part notifies the capacity shortage of the said recessed part. Then, when the selection result receiving unit receives a selection result of continuing the formation of the recess in the container film, the determination unit determines that the capacity of the recess is insufficient. It is also possible to control the recess forming portion so as to form a recess in the film for use.
  • the said recessed part formation part is provided with the some shaping
  • the determination unit has received the prescription data receiving unit whether or not the capacity of the concave portion is insufficient when the medicine for a single dose is stored in the concave portion of the molding die in use in the concave portion forming portion.
  • the control unit After determining based on prescription data and further comprising a selection result receiving unit for receiving a selection result as to whether or not to switch from the mold being used to another mold, the control unit after notifying the lack of capacity of the recess When the selection result receiving unit accepts a selection result of switching from the used mold to another mold, after switching from the used mold to another mold, It is also possible to control the recess forming portion so as to form a recess on the container film.
  • the said recessed part formation part is provided with the some shaping
  • the determination unit has received the prescription data receiving unit whether or not the capacity of the concave portion is insufficient when the medicine for a single dose is stored in the concave portion of the molding die in use in the concave portion forming portion.
  • the control unit After determining based on prescription data and further comprising a selection result receiving unit for receiving a selection result as to whether or not to switch from the mold being used to another mold, the control unit after notifying the lack of capacity of the recess When the selection result receiving unit receives a selection result indicating that the molding die in use is not switched to another molding die, the determination unit lacks the capacity of the recess. Is determined Nevertheless, it is also possible to control the recess forming portion so as to form a recess on the container film.
  • the prescription data includes information on the amount of drug for a single dose, and the determination unit relates to the amount of drug for a single dose in the prescription data received by the prescription data reception unit. Based on the information, the necessary capacity of the recess necessary to accommodate the medicine for one dose is derived, and the derived necessary capacity is formed on the container film by the molding die used in the recess forming section. It can also be determined that the capacity of the recess is insufficient when the capacity of the recess is larger.
  • the prescription data includes information on prescriptions for multiple doses, and includes information on the amount of medicine for each dose, and the determination unit receives the prescription data receiving unit. Based on the information on the amount of medicine for each dose in the prescription data, the largest necessary capacity is derived from each of the necessary capacity of the recesses necessary to accommodate the medicine for each dosage, and the most derived Based on the large required capacity, it can also be determined whether the capacity of the recess is insufficient.
  • the prescription data includes information on prescriptions for multiple doses, and includes information on the amount of medicine for each dose, and the determination unit receives the prescription data receiving unit. Based on the information on the amount of drug for each dose in the prescription data, each of the required capacity of the recess necessary to accommodate the drug for each dose is derived, and based on each of the derived required capacity, It can also be determined whether the capacity of the recess is insufficient.
  • the said judgment part can also derive
  • medical agent supply apparatus which concerns on an example of the structure of this invention is equipped with the said recessed part formation apparatus and the chemical
  • medical agent packaging apparatus which concerns on an example of the structure of this invention packages a chemical
  • FIG. 1 It is a figure which shows the outline of a structure of a chemical
  • the drug packaging device 1 of the present embodiment is a device that forms a drug package P by automatically packaging the drug M using the packaging sheet 3 and the lid sheet 4.
  • the medicine packaging apparatus 1 includes a packaging sheet holding unit 11, a packaging sheet supply unit 12, a recess forming unit 13, a drug supply unit 14, a drug feeding unit 15, a lid sheet holding unit 16, a lid.
  • a sheet supply unit 17, a lid sheet bonding unit 18, a cutting unit 19, and a printing unit 20 are provided. Each unit is controlled by the control unit 5.
  • the recess forming unit 13 and the drug supply unit 14 constitute a drug supply device.
  • the packaging sheet holding unit 11 holds a flat packaging sheet (container film) 3.
  • the packaging sheet 3 is a resin sheet.
  • As the packaging sheet 3 of the present embodiment for example, a thermoplastic resin sheet is used.
  • the packaging sheet 3 has a long band shape, and is held in a wrapping roll-like body 3 a so as to be drawable by the packaging sheet holding unit 11.
  • the dimension in the width direction of the packaging sheet 3 is a dimension that allows one recess 31 to be formed.
  • the flat packaging sheet 3 is not limited to a long belt shape, but is a rectangular shape in plan view (short), and is configured such that a plurality of packaging sheets 3 are stacked on the packaging sheet holding portion 11. You can also.
  • the packaging sheet 3 of this embodiment is transparent. For this reason, it is easy to visually recognize the medicine M stored in the recess 31 in the state after packaging.
  • a transparent packaging sheet 3 is used, but the packaging sheet 3 is not necessarily transparent.
  • the packaging sheet 3 may be translucent or opaque, for example.
  • the packaging sheet 3 in a rolled state can be held by the packaging sheet holding unit 11.
  • the packaging sheet 3 having a rectangular shape in plan view can be configured to be stacked and held on the packaging sheet holding unit 11. That is, the packaging sheet holding part 11 can hold the packaging sheet 3 in an amount sufficient to form a large number of medicine packaging bodies P at a time. For this reason, it is not necessary to set the trays having the storage recesses one by one as in the prior art. For this reason, the operator of the medicine packaging apparatus is freed from complicated work.
  • the “flat” includes a form in which irregularities and patterns that do not hinder the formation of the concave portion 31 by the concave portion forming portion 13 described later are formed.
  • the packaging sheet supply unit 12 takes out the packaging sheet 3 from the packaging sheet holding unit 11 and supplies it in the longitudinal direction.
  • the packaging sheet 3 is supplied while the tension is adjusted by a plurality of rollers 121... 121 as shown. Since a driving force is transmitted to some rollers (not shown) provided immediately upstream of the below-described cutting portion 19, the packaging sheet 3 is pulled. For this reason, the packaging sheet 3 is taken out from the packaging sheet holding unit 11.
  • the supply of the packaging sheet 3 is stopped when the recess 31 is formed in the packaging sheet 3 by a molding die 133 described later. For this reason, the supply is made intermittently. Since the packaging sheet supply unit 12 can automatically form the packaging sheet 3 that is supplied and then the medicine M can be charged, the packaging sheet can be easily packaged.
  • the means for taking out the packaging sheet 3 is not limited to a roller.
  • a means for taking out the packaging sheet 3 for example, a means for sandwiching and pulling the packaging sheet 3 may be employed. Further, as this means, various means such as an arm and a rubber plate can be adopted.
  • the packaging sheet supply unit 12 is configured so that the packaging sheet 3 can be taken out from the packaging sheet holding unit 11 one by one.
  • the recessed part forming part 13 constitutes a part of the recessed part forming apparatus X, and forms a plurality of recessed parts 31... 31 at predetermined intervals in the longitudinal direction on the packaging sheet 3 supplied by the packaging sheet supply part. .
  • the formed recesses 31 can contain the medicine M.
  • the recess forming part 13 includes a hot plate 131, a receiving part 132, and a molding die 133.
  • a plurality of molding dies 133... 133 having at least different shapes of the female dies 133 a are provided so that the concave portions 31 having different capacities can be formed by the respective molding dies 133. Details of the recess forming device X will be described later.
  • the hot plate 131 and the receiving portion 132 are opposed to each other with the conveyed packaging sheet 3 interposed therebetween. Each surface where the hot plate 131 and the receiving portion 132 face each other is a flat surface. With respect to the packaging sheet 3, the hot plate 131 is positioned below and the receiving portion 132 is positioned above. The arrangement of the hot plate 131 and the receiving part 132 with respect to the packaging sheet 3 may be reversed.
  • the heat plate 131 has a built-in heater.
  • the receiving part 132 is made of resin.
  • the receiving part 132 of this embodiment is made of rubber. The hot plate 131 and the receiving portion 132 can be moved toward and away from the packaging sheet 3 by being driven by an electric motor.
  • the drive source for driving the heat plate 131 and the receiving part 132 is not limited to the electric motor.
  • the drive source of the hot plate 131 and the receiving portion 132 may be any as long as the hot plate 131 and the receiving portion 132 can be moved toward and away from the packaging sheet 3.
  • the drive source of the hot plate 131 and the receiving part 132 may be, for example, an air cylinder or a hydraulic cylinder. In a state where the heater is energized and the hot plate 131 is heated, the hot plate 131 and the receiving part 132 approach so as to sandwich the packaging sheet 3, whereby the packaging sheet 3 can be softened.
  • the hot plate 131 and the receiving portion 132 are formed to have a size of two packages (two concave portions 31) in the longitudinal direction.
  • the packaging sheet 3 moves intermittently so that the concave portion 31 is formed for every single package (one concave portion 31) by the molding die 133. With this intermittent movement, the packaging sheet 3 is heated twice and then supplied to the mold 133. For this reason, since the first heating is “preliminary heating” and the second heating is “main heating”, the packaging sheet 3 can be sufficiently softened due to the formation of the recess 31.
  • the hot plate 131 and the receiving part 132 are not necessarily formed to have a size of two packages (two concave parts 31) in the longitudinal direction.
  • the hot plate 131 and the receiving portion 132 may be formed in a size of one package (one recess 31) in the longitudinal direction. If the packaging sheet 3 is not sufficiently softened even by two heatings, the hot plate 131 and the receiving portion 132 may be formed in a size of three packages (three concave portions 31) or more in the longitudinal direction. .
  • the forming die 133 is located downstream of the hot plate 131 and the receiving portion 132 in the sheet conveying direction.
  • the molding die 133 includes a female die 133a positioned below the packaging sheet 3 to be conveyed, a male die 133b positioned above, and a pressing plate 133c.
  • the female mold 133a and the male mold 133b have a shape corresponding to the recess 31 so that the recess 31 having a desired diameter and size can be formed.
  • the concave portion 31 formed in the present embodiment has a circular cross-sectional shape, and has a shape in which the diameter dimension decreases as it goes downward as illustrated.
  • a plurality of suction holes are formed on the concave molding surface of the female die 133a.
  • the female mold 133a, the male mold 133b, and the presser plate 133c can be moved toward and away from the packaging sheet 3.
  • the female mold 133a, the male mold 133b, and the pressing plate 133c are driven by an electric motor so that the packaging sheet 3 can be approached and separated.
  • the drive source for driving the female mold 133a, the male mold 133b, and the presser plate 133c is not limited to the electric motor.
  • the driving source of the female mold 133a, the male mold 133b, and the presser plate 133c may be any as long as the female mold 133a, the male mold 133b, and the presser plate 133c can be moved toward and away from the packaging sheet 3.
  • the drive source of the female mold 133a, the male mold 133b, and the presser plate 133c may be, for example, an air cylinder or a hydraulic cylinder.
  • the male mold 133b and the holding plate 133c approach the female mold 133a so as to sandwich the packaging sheet 3 softened by the hot plate 131. While the packaging sheet 3 is sandwiched between the female mold 133a and the presser plate 133c, air is sucked from the plurality of suction holes, whereby a recess 31 that is recessed downward is formed in the packaging sheet 3. In this state, the concave part 31 having a desired shape is reliably formed by further fitting the male mold 133b to the female mold 133a.
  • the male mold 133b is not necessarily provided.
  • the male mold 133b may be omitted if the concave portion 31 having a desired shape can be formed by sucking air from the plurality of suction holes of the female mold 133a.
  • one set of the molding die 133 of the present embodiment is provided, and is configured to form one recess 31 at a time (one cycle of vertical movement of the female die 133a and the male die 133b).
  • a plurality of sets of molding dies 133 in parallel along the longitudinal direction of the packaging sheet 3 or in the width direction of the packaging sheet 3 (front and back direction in FIG. 1), a plurality of recesses 31. 31 can also be formed.
  • the drug supply unit 14 temporarily stores the drug M. Then, the medicine supply unit 14 supplies the medicine M to the medicine input unit 15 according to prescription data that is data including prescription information (for example, for each dose). Thereby, the medicine M is supplied to the concave portion 31 formed in the packaging sheet 3 by the concave portion forming portion 13.
  • the drug supply unit 14 includes a storage unit 141 that temporarily stores the drug M.
  • the drug supply unit 14 can selectively supply the drug M from the storage unit 141 under the control of the control unit 5.
  • the storage unit 141 for tablets there can be exemplified a storage cassette and each recess in a distribution basket in which a plurality of recesses are arranged in a matrix.
  • the storage unit 141 is for powders, for example, a saddle with a V-shaped concave section and a powder distribution device formed in a disc shape and configured to scrape powder according to prescription data. it can.
  • the medicine supply unit 14 is not limited to these exemplified forms and can be implemented in various forms.
  • the storage unit 141 can be configured by, for example, a plurality of storage units for each type that store the medicine M for each type, or a plurality of storage units for each dose that stores the drug M for each dose. It is.
  • the medicine supply unit 14 can store the medicine M for each type or for each dose in a state suitable for supplying the medicine M.
  • the medicine M can be easily replenished.
  • the medicine M when the medicine M is stored for each dose by the dose storage unit, it can be supplied to the drug input unit 15 in the stored state.
  • the drug supply unit 14 of the present embodiment can handle drugs of various dosage forms. For example, a tablet, a capsule, and a powder are mentioned. Further, in the present embodiment, it is configured to handle only a solid drug, but depending on the case, it is also possible to handle a liquid or gel drug.
  • the drug injection unit 15 inputs the drug M into each recess 31 formed in the packaging sheet 3 by the recess forming unit 13.
  • the medicine charging unit 15 of the present embodiment is configured as a hopper having an upward shape, and is positioned below the medicine supply unit 14.
  • the medicine feeding section 15 is formed in a shape suitable for dispensing such as a nozzle shape.
  • the lid sheet holding unit 16 holds the flat lid sheet 4.
  • a resin sheet is used as the lid sheet 4 of the present embodiment.
  • the lid sheet 4 has a strip shape.
  • the lid sheet 4 is held in such a manner that it can be pulled out to the lid sheet holding portion 16 in the state of a rolled roll 4a.
  • the lid sheet 4 has a width that can cover the opening of the recess 31 formed in the packaging sheet 3.
  • the width of the lid sheet 4 of the present embodiment is the same as the width of the packaging sheet 3.
  • paper or paper coated with resin can be used as the cover sheet 4.
  • the lid sheet supply unit 17 applies the lid sheet 4 for closing the opening of the concave portion 31 to the packaging sheet 3 in the state where the concave portions 31... To supply.
  • the lid sheet supply unit 17 supplies the lid sheet 4 to the upper surface of the packaging sheet 3.
  • the lid sheet supply unit 17 supplies the lid sheet 4 to the packaging sheet 3 from above.
  • the lid sheet supply unit 17 may supply the lid sheet 4 to the packaging sheet 3 from the side or from below.
  • the lid sheet supply unit 17 takes out the lid sheet 4 from the lid sheet holding unit 16 and supplies it in the longitudinal direction.
  • the lid sheet 4 is supplied while the tension is adjusted by a plurality of rollers 171.
  • the lid sheet 4 Since the driving force is transmitted to some rollers (not shown) provided at the closest position on the upstream side of the cutting portion 19 described later, the lid sheet 4 is pulled. For this reason, the lid sheet 4 is taken out from the lid sheet holding part 16.
  • the packaging sheet 3 and the lid sheet 4 are pulled by a common roller.
  • the supply is stopped when the lid sheet 4 is bonded to the packaging sheet 3 by the lid sheet bonding portion 18 described later. For this reason, the supply is made intermittently.
  • the intermittent supply of the lid sheet 4 is synchronized with the supply of the packaging sheet 3.
  • the means for taking out the lid sheet 4 is not limited to a roller.
  • a means for taking out the lid sheet 4 for example, a means for sandwiching and pulling the lid sheet 4 may be employed. Further, as this means, various means such as an arm and a rubber plate can be adopted.
  • the lid sheet bonding unit 18 bonds the lid sheet 4 supplied by the lid sheet supply unit 17 to the packaging sheet 3 in a state where the lid sheet 4 is closed by covering the opening of the recess 31.
  • the lid sheet bonding part 18 includes a hot plate 181 and a receiving part 182.
  • the hot plate 181 and the receiving portion 182 are opposed to each other with the lid sheet 4 to be conveyed and the portion of the packaging sheet 3 where the concave portion 31 is not formed interposed therebetween.
  • Each surface where the heat plate 181 and the receiving portion 182 face each other is a flat surface.
  • the heat plate 181 is located above and the receiving portion 182 is located below.
  • the heating plate 181 has a built-in heater.
  • the receiving part 182 is made of resin.
  • the receiving portion 182 of this embodiment is made of rubber.
  • the receiving portion 182 may be another hot plate in which a heater is built.
  • the hot plate 181 and the receiving portion 182 can be moved toward and away from the lid sheet 4 and the packaging sheet 3 by being driven by an electric motor.
  • the drive source for driving the heat plate 181 and the receiving part 182 is not limited to the electric motor.
  • the drive source of the hot plate 181 and the receiving portion 182 may be any drive source that can move the hot plate 181 and the receiving portion 182 toward and away from the lid sheet 4 and the packaging sheet 3.
  • the drive source of the hot plate 181 and the receiving part 182 may be, for example, an air cylinder or a hydraulic cylinder.
  • the receiving portion 182 is formed with a recess into which the recessed portion 31 is fitted so that the receiving portion 182 and the recessed portion 31 do not interfere with each other.
  • a circular hole passes through the center of the receiving portion 182 as a recess so that it does not interfere with the concave portion 31 when the receiving portion 182 moves upward.
  • the cutting unit 19 cuts the packaging sheet 3 to which the lid sheet 4 is bonded together with the sheets 3 and 4 together for one or more doses.
  • the cutting unit 19 of the present embodiment includes cutting blades 191 and 191 that are positioned above and below the packaging sheet 3 and are movable so that the blade edges overlap. Thereby, the medicine package P is separated into units that are easy for the patient to take. Accordingly, it is possible to obtain a medicine package P that is grouped in one or more dose units.
  • a perforation can be formed in the packaging sheet 3 and the lid sheet 4 by changing the shape of the cutting blade 191.
  • the medicine package P can be appropriately cut according to the convenience of the patient, so that the patient's convenience is improved when taking or storing the medicine package P.
  • the printing unit 20 prints information corresponding to the prescription data on the lid sheet 4. Since the printing unit 20 can perform printing in a series of steps, it is possible to easily form the medicine package P up to a state where it can be delivered to the patient. Examples of the printed contents include the patient's name, the date of taking, the day of the week, and the timing of taking (after meal, before meal, between meals, etc.). In this embodiment, printing is performed on the lid sheet 4 before being bonded to the packaging sheet 3. For this reason, the printing part 20 is located above the conveyance line of the packaging sheet 3. Note that printing can also be performed on the lid sheet 4 after being bonded to the packaging sheet 3. Examples of the printing method include a method of thermal transfer using an ink ribbon, but various methods such as an ink jet method can be adopted.
  • the recess forming device X will be described below. As shown in FIG. 2 (block diagram), the recess forming device X of the present embodiment includes the above-described recess forming unit 13, the mold switching unit 21, the prescription data receiving unit 22, the determining unit 23, the notifying unit 24, A recess formation / notification control unit (“control unit” described in claims) 25 and a selection result receiving unit 26 are provided. The molding die switching unit 21 and the selection result receiving unit 26 may not be provided in the recess forming device X.
  • Each of the plurality of molds 133... 133 provided in the recess forming part 13 has different capacities (volumes in this embodiment) of the recesses 31... 31 formed in the packaging sheet 3. For this reason, in the plurality of molds 133... 133, at least the female mold 133a (particularly, the mold recesses 133a1 to 133a3 that are the recesses of the female mold 133a that deform the packaging sheet 3) have different shapes.
  • the different capacities of the recesses 31... 31 can be realized by a plurality of molds 133... 133 in which the cross-sectional dimensions and depth dimensions of the mold recesses 133a1 to 133a3 in the female mold 133a are proportional. Further, the ratio of the cross-sectional dimension and the depth dimension of the mold recess in the female mold 133a is changed (for example, only the cross-sectional dimension is changed or only the depth dimension is changed). 133 can also be realized. Further, it can also be realized by a plurality of molding dies 133... 133 that have different cross-sectional shapes of the mold recesses in the female mold 133a (for example, a circular cross-sectional shape and a quadrangular cross-sectional shape exist). In this way, different capacities can be realized by various patterns of the plurality of molds 133.
  • the molding die switching unit 21 switches the molding die 133 used in the recess forming unit 13 among the plurality of molding dies 133. This switching is performed so that the molding die 133 selected from the plurality of molding dies 133... Note that the number of molds 133 selected at a time in the present embodiment is one, but is not limited to this. For example, when the recess forming portion 13 is configured to simultaneously form a plurality of recesses 31... 31. Can also select two or more molds 133 at a time.
  • the mold switching unit 21 may be omitted when the mold 133 is not switched or when a user such as a pharmacist switches the mold 133 by hand.
  • FIGS. 3 to 6 illustrate the configuration of the molding die switching unit 21.
  • FIG. 3 to 5 uses a mold assembly 133u integrated with at least the female mold 133a, and the configuration example shown in FIG. 6 includes a plurality of molding dies 133 ... 133 (female molds). 133a... 133a) are used individually.
  • the molding die assembly 133u includes a female die 133a having a plurality of (three in this configuration example) mold recesses 133a1 to 133a3 having different sizes.
  • the female mold 133a has a rectangular shape in plan view, and the mold recesses 133a1 to 133a3 are arranged in the longitudinal direction.
  • On the lower side surface of the female die 133a there is provided a die moving rack 211 that is a gear that is linear in the longitudinal direction.
  • a mold moving motor 212 is provided for rotating a drive-side pinion 212a (tooth is not shown) positioned so as to mesh with the teeth of the mold moving rack 211.
  • the female mold 133a By rotating the mold moving motor 212, the female mold 133a can be moved in the longitudinal direction (the arrow direction in the figure).
  • the male mold 133b (if provided) and the holding plate 133c are also shaped to correspond to the mold recesses 133a1 to 133a3, and are configured to move in parallel with the movement of the female mold 133a. Has been.
  • the configuration example shown in FIG. 4 is common to the configuration example shown in FIG. 3 in that the female die 133a having a rectangular shape in plan view can be moved in the longitudinal direction with respect to the mold assembly 133u.
  • this configuration example is different in that a die moving cylinder 213 is connected to the longitudinal end of the female die 133a. By expanding and contracting the mold moving cylinder 213, the female mold 133a can be moved in the longitudinal direction (the direction of the arrow in the figure).
  • the mold assembly 133u includes a hexagonal column-shaped female mold 133a having a plurality of mold recesses 133a1 to 133a3 of different sizes, one on each outer peripheral surface. .
  • a mold moving gear 214 is provided on one end face of the female mold 133a.
  • a mold moving motor 215 that rotates a driving gear 215a (tooth not shown) positioned so as to mesh with the teeth of the mold moving gear 214 is provided. By rotating the mold moving motor 215, the female mold 133a can be moved in the circumferential direction (arrow direction in the figure).
  • the male mold 133b (if provided) and the holding plate 133c in this configuration are also shaped to correspond to the mold recesses 133a1 to 133a3, and are configured to move relative to the female mold 133a. Has been.
  • a plurality of female molds 133 a... 133 a each having a mold recess having a different size are stored in the storage unit 216, for example, on the mold table 218 using the robot arm 217. Can be replaced.
  • the configuration of the molding die switching unit 21 is not limited to the above examples, and various configurations can be adopted.
  • the prescription data receiving unit 22 receives prescription data input to the medicine packaging device 1 (particularly the recess forming device X).
  • the prescription data may be input manually by a user such as a pharmacist or may be automatically performed by an input device connected to the drug packaging device 1 (recess forming device X).
  • the determination unit 23 stores the medicine M for a single dose in the recess 31 formed on the packaging sheet 3 by the molding die 133 being used in the recess forming unit 13, the capacity of the recess 31 is insufficient (this) That is, whether or not the supplied medicine M may overflow from the recess 31) is determined based on the prescription data received by the prescription data receiving unit 22. The criteria for judgment will be described later.
  • the notification unit 24 When the determination unit 23 determines that the capacity of the recess 31 is insufficient, the notification unit 24 notifies the user that the capacity of the recess 31 is insufficient.
  • the notification unit 24 of the present embodiment is a display unit provided in the medicine packaging device 1 and notifies the user by visual display. Various display means can be adopted for the display unit. In addition, the display unit originally provided in the medicine packaging device 1 can also serve as the notification unit 24.
  • the recess formation / notification control unit 25 forms the recess 31 so as to form the recess 31 in the packaging sheet 3 as it is (without switching the molding die 133).
  • the unit 13 is controlled.
  • the recess formation / notification control unit 25 controls the notification unit 24 to notify the user that the capacity of the recess 31 is insufficient.
  • This recess formation / notification control unit 25 can be provided in the control unit 5 of the medicine packaging apparatus 1 as shown in FIG. It can also be provided).
  • the recess forming device X having the configuration described so far, it is possible to notify the user of the capacity shortage of the recess 31 formed by the molding die 133 being used in the recess forming part 13 according to the prescription data. For this reason, when the user responds to the notification, for example, by switching to another mold 133, it is possible to form an appropriate recess 31.
  • the selection result receiving unit 26 receives the selection result selected by the user.
  • the selection result the selection result of whether to continue or stop the formation of the recess 31 in the packaging sheet 3 and whether to switch the molding die 133 can be exemplified, but other various selection results It may be.
  • the recess formation / notification control unit 25 performs control described later.
  • the selection result receiving unit 26 is connected to an input unit provided in the medicine packaging device 1. Various input means can be employed for this input unit.
  • an input unit originally provided in the medicine packaging device 1 can be connected to the selection result receiving unit 26.
  • the control content of the recess formation / notification control unit 25 according to the selection result received by the selection result receiving unit 26 will be described.
  • the notification unit 24 notifies the user that the capacity of the recess 31 is insufficient
  • the selection result receiving unit 26 receives a selection result of continuing the formation of the recess 31 on the packaging sheet 3, the determination unit 23.
  • the recess formation / notification control unit 25 controls the recess formation unit 13 so as to form the recess 31 in the packaging sheet 3. By such control, it is possible to select the continuation or cancellation of the formation of the recess 31 at the user's judgment, so that the flexible recess 31 can be formed flexibly.
  • the medicine M may actually be supplied without overflowing the concave portion 31, so that the concave portion can be provided according to the user's experience. 31 can be formed.
  • the concave portion formation / notification control unit 25 The concave portion forming portion 13 is controlled so as to form the concave portion 31 in the packaging sheet 3 by switching the molding die 133 by the switching portion 21 or by the user's hand. By such control, it is possible to select whether or not to switch the molding die 133 at the user's discretion, so that the flexible recess 31 can be formed flexibly.
  • the concave portion 31 can be actually formed without switching the mold 133 and the medicine M can be supplied without overflowing the concave portion 31. Since there is a case, formation of the recessed part 31 can be performed according to a user's experience.
  • the determination unit 23 has insufficient capacity of the recess 31.
  • the recess formation / notification control unit 25 controls the recess formation unit 13 so as to form the recess 31 in the packaging sheet 3 as it is. By such control, it is possible to select whether or not to switch the molding die 133 at the user's discretion, so that the flexible recess 31 can be formed flexibly. Even if the notification unit 24 notifies the user that the capacity of the concave portion 31 is insufficient, the medicine M may actually be supplied without overflowing from the single concave portion 31, depending on the user's experience. Thus, the recess 31 can be formed.
  • the prescription data may include information on the amount of drug for a single dose.
  • the determination unit 23 has a recess 31 necessary for accommodating the medicine M for a single dose based on the information regarding the amount of the drug for a single dose in the prescription data received by the prescription data reception unit 22.
  • the required capacity of is derived.
  • the determination unit 23 determines that the capacity of the recessed portion 31 is insufficient when the derived necessary capacity is larger than the capacity of the recessed portion 31 formed by the molding die 133 used in the recessed portion forming section 13.
  • “derivation” in the present embodiment includes not only calculation by calculation but also derivation by referring to a table stored in the determination unit 23 or the like in advance, and allows various procedures.
  • the required capacity can be derived in consideration of a predetermined margin rate.
  • the required volume is derived based on the information on the amount of drug for a single dose in the prescription data, and based on this required volume It can be determined whether or not the capacity of the recess 31 is insufficient. For this reason, it can be determined appropriately whether the capacity
  • the determination unit 23 of the present embodiment derives the necessary volume of the recess 31 necessary for accommodating the medicine M for one dose as the necessary capacity.
  • the required volume takes into account, for example, the volume of the drug M (the volume of the solid part) and the volume of the gap (the volume of the space part) that is expected to be formed around the drug M in the state of being inserted into the recess 31.
  • the derivation is performed in accordance with, for example, a combination of medicines M in a single dose.
  • the prescription data includes information on prescriptions for a plurality of doses, and can also include information on the amount of drug for each dose.
  • the determination unit 23 derives the largest necessary capacity among the necessary capacity for the medicine M for each dose, based on the information regarding the medicine amount for each dosage.
  • the determination unit 23 determines whether or not the capacity of the recess 31 is insufficient based on the derived maximum required capacity. In this case, since it can be determined in a prescription unit whether the capacity of the recess 31 is insufficient, the medicine can be supplied to the recess 31 having an appropriate capacity in the prescription unit.
  • the determination unit 23 is based on the information on the drug amount for each dose. Then, each of the necessary capacities for the medicine M for each dose is derived, and based on each of the derived necessary volumes, it is determined whether or not the capacity of the recess 31 is insufficient. In this case, since it is possible to determine whether or not the capacity of the recess 31 is insufficient for each dose, the medicine can be supplied to the recess 31 having an appropriate capacity for each dose.
  • the recess forming device X of the present embodiment seals the recess 31 in a state where the drug M supplied by the drug supply unit 14 is accommodated in the recess 31 formed in the packaging sheet 3 by the recess forming unit 13.
  • the medicine packaging apparatus 1 can be configured in combination with a medicine packaging unit for packaging medicine M.
  • the medicine packaging unit includes the lid sheet holding unit 16, the lid sheet supply unit 17, and the lid sheet bonding unit 18 described above. This medicine packaging apparatus 1 can perform a series of formation of the recess 31 in the packaging sheet 3 and sealing with the medicine M accommodated in the formed recess 31.
  • FIG. 1 An example of the operation flow is shown in FIG.
  • a plurality of molds 133... 133 are used.
  • the required volume is derived (step S1).
  • step S2 If NO in step S2 ("NO" in FIG. 7, the same applies hereinafter), the notification unit 24 notifies the user of an error regarding insufficient volume (step S4), and then the selection result receiving unit. It is determined from the selection result received by 26 whether or not to stop the supply of the medicine M to the recess 31 (step S5). If it is right, the process ends. If not, the process moves to step S3. Note that step S5 may be omitted.
  • FIG. 8 shows a flow when the mold 133 is switched. Steps S1 to S4 in this flow are the same as steps S1 to S4 in the operation flow of FIG.
  • step S4 it is determined from the selection result received by the selection result receiving unit 26 whether or not to switch the plurality of molding dies 133 ... 133 (step S6). If YES, the mold 133 is switched by the mold switching unit 21 or by the user's hand. If not, the process moves to step S3.
  • step S6 it is determined whether or not the switching of the mold 133 has been completed (step S7).
  • step S7 when switching the shaping
  • the medicine packaging device 1 including the recess forming device X of the present embodiment configured as described above, the supply of the packaging sheet, the formation of the plurality of recesses 31. Can do. Therefore, blister packaging can be easily performed.
  • the recess forming unit 13 includes a plurality of molds 133... 133, but may include only one mold 133. In this case, the mold switching unit 21 is unnecessary.
  • the concave part forming apparatus X uses the molding die 133 to form the concave part 31 for accommodating the medicine M in the packaging sheet (container film) 3 and information on prescription.
  • the recess forming section 13 and the prescription data receiving section 22 that receives prescription data including A determination unit 23 that determines whether or not the capacity of the recess 31 is insufficient based on the prescription data received by the prescription data reception unit 22, a notification unit 24 for notifying the capacity shortage of the recess 31, and the determination
  • the recess forming portion 1 is formed so as to form the recess 31 in the packaging sheet (container film) 3.
  • the recess formation / notification control unit controls the notification unit 24 to notify the user of the capacity shortage of the recess 31. 25.
  • the lack of capacity of the recess 31 is notified according to the prescription data. For this reason, when the user responds to the notification, the appropriate recess 31 can be formed.
  • the said recessed part formation apparatus X is further provided with the selection result reception part 26 which receives the selection result whether it continues or stops formation of the recessed part 31 to the packaging sheet (container film) 3, and the said recessed part formation
  • the notification control unit receives a selection result that the formation of the recess 31 on the packaging sheet (container film) 3 is continued by the selection result receiving unit 26 after notifying that the capacity of the recess 31 is insufficient.
  • the determination unit 23 determines that the capacity of the recess 31 is insufficient, the recess forming unit 13 may be controlled to form the recess 31 in the packaging sheet (container film) 3. it can.
  • the said recessed part formation part 13 is equipped with the some shaping
  • the capacities of the recesses 31 formed in the sheet (container film) 3 are different from each other, and the determination unit 23 stores the medicine M for a single dose in the recess 31 by the molding die 133 in use in the recess formation unit 13.
  • the flexible concave portion 31 can be formed flexibly.
  • the said recessed part formation part 13 is equipped with the some shaping
  • the capacities of the recesses 31 formed in the sheet (container film) 3 are different from each other, and the determination unit 23 stores the medicine M for a single dose in the recess 31 by the molding die 133 in use in the recess formation unit 13.
  • the flexible concave portion 133 can be formed flexibly.
  • the prescription data includes information on the amount of medicine for a single dose, and the determination unit 23 is a medicine for a single dose in the prescription data received by the prescription data reception unit 22. Based on the information on the amount, a necessary capacity of the concave portion 31 necessary for accommodating the medicine M for one dose is derived, and the derived necessary capacity is determined by the mold 133 used in the concave portion forming section 13. When the capacity of the recess 31 formed on the packaging sheet (container film) 3 is larger than the capacity of the recess 31, it can be determined that the capacity of the recess 31 is insufficient.
  • the necessary capacity is derived based on the information on the amount of medicine for a single dose in the prescription data, and it is determined whether or not the capacity of the recess 31 is insufficient based on this necessary capacity. It can be appropriately determined whether or not the capacity of the recess 31 is insufficient.
  • the prescription data includes information about prescriptions for a plurality of doses, and information about the amount of medicine for each dose, and the determination unit 23 receives the prescription data reception unit 22. Further, in the prescription data, based on the information about the amount of medicine for each dose, the largest necessary capacity is derived among the necessary capacity of the recess 31 necessary to accommodate each dose of medicine, It can be determined whether or not the capacity of the recess 31 is insufficient based on the derived maximum required capacity.
  • the recess 31 can be appropriately formed in a prescription unit.
  • the prescription data includes information about prescriptions for a plurality of doses, and information about the amount of medicine for each dose, and the determination unit 23 receives the prescription data reception unit 22.
  • each of the necessary capacity of the recess 31 required to accommodate the medicine for each dose is derived, and each of the derived necessary capacity is Based on this, it can be determined whether or not the capacity of the recess 31 is insufficient.
  • the recess 31 since it is possible to determine whether or not the capacity of the recess 31 is insufficient for each dose, the recess 31 can be appropriately formed for each dose.
  • the said judgment part 23 can also derive
  • the required capacity can be easily derived by using the required volume.
  • the drug supply device includes the recess forming device X and the drug supply unit 14 that supplies the drug M to the recess 31 formed by the recess forming device X.
  • the formation of the recess 31 in the packaging sheet (container film) 3 and the supply of the drug M to the formed recess 31 can be performed in series.
  • the medicine packaging device 1 includes the concave portion 31 in a state where the medicine M is accommodated in the concave portion forming device X and the concave portion 31 formed by the concave portion forming device X. By sealing, a medicine packaging part for packaging medicine M is provided.
  • the user can respond to the notification of insufficient capacity of the recess 31 according to the prescription data, so that the appropriate recess 31 can be formed.
  • the recessed part formation apparatus X suitable for performing an appropriate packaging with respect to the prescribed chemical

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  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Fluid Mechanics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne un dispositif de formage d'évidement qui est équipé : d'une unité (13) de formage d'évidement qui utilise une matrice de formage pour former un évidement destiné à recevoir un médicament dans un film de contenant ; d'une unité (22) de réception de données de prescription qui reçoit des données de prescription comprenant des informations concernant une prescription ; d'une unité de détermination (23) qui détermine, sur la base des données de prescription reçues par l'unité (22) de réception de données de prescription, si la capacité de l'évidement formé dans le film de contenant par l'unité (13) de formage d'évidement est insuffisante pour recevoir une dose unique de médicament dans l'évidement ; d'une unité de notification (24) qui envoie une notification selon laquelle la capacité de l'évidement est insuffisante ; et d'une unité de commande (25) qui, dans les cas où l'unité de détermination (23) a déterminé que la capacité de l'évidement n'est pas insuffisante, commande à l'unité (13) de formage d'évidement de former des évidements dans le film de contenant, et dans les cas où l'unité de détermination (23) a déterminé que la capacité de l'évidement est insuffisante, commande à l'unité de notification (24) de notifier à l'utilisateur que la capacité de l'évidement est insuffisante.
PCT/JP2016/088391 2015-12-24 2016-12-22 Dispositif de formage d'évidement, et dispositif de distribution de médicament et dispositif de conditionnement de médicament équipé de celui-ci WO2017111026A1 (fr)

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JP2015251732A JP2017113275A (ja) 2015-12-24 2015-12-24 凹部形成装置及びこれを備えた薬剤供給装置、薬剤包装装置
JP2015-251732 2015-12-24

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751805A (en) * 1986-02-24 1988-06-21 Hassia Verpackungsmaschinen Gmbh Packing machine
JPH09202301A (ja) * 1996-01-25 1997-08-05 Yuyama Seisakusho:Kk 薬剤分包方法と検薬方法
JP2000185703A (ja) * 1998-12-21 2000-07-04 Tooshoo:Kk 薬剤分包機
JP2013220832A (ja) * 2012-04-16 2013-10-28 Sumitomo Bakelite Co Ltd 薬剤包装体製造装置および薬剤包装体
JP2014213116A (ja) * 2013-04-30 2014-11-17 キヤノンマーケティングジャパン株式会社 コンピュータ、分包装置、錠剤供給装置およびその制御方法とプログラム。

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751805A (en) * 1986-02-24 1988-06-21 Hassia Verpackungsmaschinen Gmbh Packing machine
JPH09202301A (ja) * 1996-01-25 1997-08-05 Yuyama Seisakusho:Kk 薬剤分包方法と検薬方法
JP2000185703A (ja) * 1998-12-21 2000-07-04 Tooshoo:Kk 薬剤分包機
JP2013220832A (ja) * 2012-04-16 2013-10-28 Sumitomo Bakelite Co Ltd 薬剤包装体製造装置および薬剤包装体
JP2014213116A (ja) * 2013-04-30 2014-11-17 キヤノンマーケティングジャパン株式会社 コンピュータ、分包装置、錠剤供給装置およびその制御方法とプログラム。

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TW201729781A (zh) 2017-09-01

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