WO2017045249A1 - Traditional chinese medicine for treating hyperlipemia and preparation method thereof - Google Patents

Abstract

Disclosed is a traditional Chinese medicine for treating hyperlipemia, wherein the traditional Chinese medicine comprises the following components in parts by weight: 30-40 parts of rhizoma alismatis, 30-40 parts of oriental wormwood, 30-40 parts of the root of the kudzu vine, 25-30 parts of seaweed, 25-30 parts of kelp, 25-30 parts of radix bupleuri, 25-30 parts of radix angelicae, 25-30 parts of radix curcumae, 15-25 parts of pericarpium citri reticulatae, 15-25 parts of platycodon grandiflorum, 15-25 parts of fructus trichosanthis, 10-15 parts of rhizoma drynariae, 10-15 parts of the seeds of Chinese dodder, 5-10 parts of fructus cannabis, and 5-10 parts of prepared rhubarb.

Description

Traditional Chinese medicine for treating hyperlipemia blood and preparation method thereof Traditional Chinese medicine for treating hyperlipemia blood and preparation method thereof

 Technical field

 The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine for treating hyperlipemia and a preparation method thereof.

 Background technique

Hyperlipidemia is a disease in which plasma cholesterol, triglyceride, and low-density lipoprotein levels are elevated and high-density lipoprotein is too low in a systemic metabolic disorder caused by various causes. There are currently three types of commonly used drugs for lowering blood fat. : clofibrate, niacin, statins. Commonly used drugs are simvastatin, lovastatin and the like. These drugs have a certain effect on lipid-lowering, but they are prone to attack after stopping the drug. Moreover, the liver and kidney function should be reviewed regularly during the medication, because these drugs are irritating to the gastrointestinal tract and have damage to the liver and kidney, and should not be taken for a long time.

In order to reduce the side effects of medication and affect liver and kidney, gastrointestinal function, traditional Chinese medicine will be used in clinical applications, but the general Chinese medicine treatment cycle is long, and the effect is not satisfactory.

 Summary of the invention

The invention discloses a traditional Chinese medicine for treating high-lipemia with safe and effective, good curative effect and a preparation method thereof for solving the existing problems. The medicine adopts pure Chinese medicine, has no side effects, has high cure rate, quick effect, is not easy to relapse, and has simple preparation method.

 A traditional Chinese medicine for treating hyperlipemia, which is mainly distributed in parts by weight:

30-40 copies of Alisma, Capillaris and Pueraria, 25-30 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 15-25 parts of dried tangerine peel, platycodon grandiflorum and whole melon, each of which is 10 and 10 -15 servings, 5-10 parts of Hemp and Rhubarb.

Further preferred as the above technical solution, the distribution ratio of the traditional Chinese medicine is mainly 35-40 parts by weight of Alisma, Capillaris, Pueraria, 25-30 parts of seaweed, kelp, Bupleurum, peony and turmeric. 15-20 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 10-15 parts of each of the broken bones and dodders, 5-10 parts of hemp and rhubarb.

Further optimizing the above technical solution, the optimal ratio of the traditional Chinese medicine to the distribution is: by weight, 36 parts of Maizhao, Yinchen and Pueraria, 28 parts of seaweed, kelp, Bupleurum, white peony and turmeric, respectively, and tangerine peel, There are 17 servings of platycodon grandiflorum and whole melon, 13 parts of sclerotium and scorpion, and 7 parts of hemp and rhubarb.

 According to the above process prescription, the specific preparation method is as follows:

 The specific steps of the preparation method are as follows:

 a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;

b. According to the formula ratio, the diarrhea, mycelium, puerarin, seaweed, kelp, chaihu, white peony, turmeric, tangerine peel, platycodon grandiflorum, whole melon stalk, smashed stalk, dodder, and hemp seed are added 5-7 times by weight. Cold water is placed in a decocting machine for 60-90 minutes, first boiled with a fire, then simmered for 1-2 hours with a simmer, filtered to obtain a filtrate b;

 c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

 Take the method: two tablets at a time, twice a day, one course a week, three courses can be cured.

 Pharmacological analysis:

Alisma can reduce low-density lipoprotein in blood, increase high-density lipoprotein, regulate blood lipids; Yinchen lowers blood fat, reduces arteriosclerosis, reduces visceral fat deposition, reduces cholesterol content in aortic wall; Pueraria has hypolipidemic effect; seaweed And Kunbu, soft and firm, reduce blood fat; Bupleurum liver and gallbladder, lowering blood fat, regulating gastrointestinal function; white sputum sweating dehumidification, reducing water molecules in the body, and can promote fat decomposition, inhibit fat synthesis; turmeric qi Activating blood, lowering blood fat; Chen Pi Li biliary, can lower serum cholesterol, reduce and improve aortic sclerosis; platycodon blood sugar and blood lipids, and can remove sputum, sputum, pus and other sticky substances; It has a laxative effect and lowers blood fat; bone shredding, dodder silk supplements the liver and kidney yang, enhances the function of liver and intestine, is conducive to the synthesis of high-density lipoprotein, enhances the function of excreting cholate in feces daily; Run dryness, prevent blood lipids from rising; make rhubarb lower serum cholesterol. The above drugs are used in combination with different aspects, synergistically, to achieve Shugan Lidan, alleviate the function of liver and intestines, thereby achieving the purpose of treating hyperlipemia.

The invention has the beneficial effects that the invention provides a traditional Chinese medicine for treating hyperlipemia and a preparation method thereof, and the traditional Chinese medicine has the functions of relieving liver and gallbladder, relieving laxative, enhancing liver and intestine functions, and effectively treating hyperlipemia disease. . The invention selects pure natural Chinese medicinal materials, has wide drug source, low price, safe and effective, convenient administration, short treatment course, good curative effect and no toxicity.

 detailed description

 Example 1

 A traditional Chinese medicine for treating hyperlipemia, which is mainly distributed in parts by weight:

There are 36 copies of Alisma, Yinchen and Pueraria, 28 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 17 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 13 parts of sclerotium and dodder, each of which is hemp, 7 parts of each rhubarb.

 According to the above process prescription, the specific preparation method is as follows:

 a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;

b. According to the formula ratio, we will add 5 times the weight of cold water to Alisma, Capillaris, Pueraria, Seaweed, Kumbu, Bupleurum, Radix, Yujin, Tangerine, Campanulaceae, Whole Melon, Gutrun, Dodder, and Hemp. Soak in the decocting machine for 60 minutes, first boil with martial art, then simmer for 1 hour with simmer, filter to obtain filtrate b;

 c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

 Example 2

 A traditional Chinese medicine for treating hyperlipemia, mainly in proportion to parts by weight:

There are 30 copies of Alisma, Capillaris and Pueraria, 25 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 15 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 10 parts of sclerotium and dodder, each of which is hemp, 5 parts of each rhubarb.

 According to the above process prescription, the specific preparation method is as follows:

 a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;

b. According to the formula ratio, we will add 7 times the weight of cold water to Alisma, Capillaris, Pueraria, Seaweed, Kumbu, Bupleurum, Radix, Yujin, Tangerine, Campanulaceae, Whole Melon, Gutrun, Dodder, and Hemp. Soak in the decocting machine for 90 minutes, first boil with Wuhu, then simmer for 2 hours with simmer, filter to obtain filtrate b;

 c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

 Example 3

 A traditional Chinese medicine for treating hyperlipemia, mainly in proportion to parts by weight:

There are 40 copies of Alisma, Yinchen and Pueraria, 30 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 25 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 15 parts of sclerotium and medlar, each of which is hemp, 10 parts of each rhubarb.

 According to the above process prescription, the specific preparation method is as follows:

 a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;

b. According to the formula ratio, we will add 6 times the weight of cold water to Alisma, Capillaris, Pueraria, Seaweed, Kumbu, Bupleurum, Radix, Yujin, Tangerine, Campanulaceae, Whole Melon, Gutrun, Cuscuta, and Hemp. Soak in the decocting machine for 70 minutes, first boil with Wuhu, then simmer for 1.5 hours with simmer, filter to obtain filtrate b;

 c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

 Example 4

 A traditional Chinese medicine for treating hyperlipemia, mainly in proportion to parts by weight:

There are 35 copies of Alisma, Capillaris and Radix Puerariae, 27 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 16 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 13 parts of sclerotium and dodder, each of which is hemp, Each of the rhubarb is 6 servings.

 According to the above process prescription, the specific preparation method is as follows:

 a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder a;

b. According to the formula ratio, we will add 5 times the weight of cold water to Alisma, Capillaris, Pueraria, Seaweed, Kumbu, Bupleurum, Radix, Yujin, Tangerine, Campanulaceae, Whole Melon, Gutrun, Dodder, and Hemp. Soak in the decocting machine for 80 minutes, first boil with martial art, then simmer for 2 hours with simmer, filter to obtain filtrate b;

 c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

 Example 5

 A traditional Chinese medicine for treating hyperlipemia, which is mainly distributed in parts by weight:

There are 33 copies of Alisma, Yinchen and Pueraria, 29 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 19 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 14 parts of sclerotium and dodder, each of which is hemp, 8 parts of each rhubarb.

 According to the above process prescription, the specific preparation method is as follows:

 a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;

b. According to the formula ratio, we will add 5 times the weight of cold water to Alisma, Capillaris, Pueraria, Seaweed, Kumbu, Bupleurum, Radix, Yujin, Tangerine, Campanulaceae, Whole Melon, Gutrun, Dodder, and Hemp. Soak in the decocting machine for 90 minutes, first boil with Wuhu, then simmer for 2 hours with simmer, filter to obtain filtrate b;

 c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

 The results of clinical observation of the present invention are as follows:

 Healing: clinical symptoms and signs completely disappear or disappear;

 Significant effect: most of the clinical symptoms and signs improved or significantly improved;

 Invalid: no significant improvement in clinical symptoms and signs, the symptoms are as before, the effect is not obvious.

Treatment results: a total of 50 patients, each taking 10 patients, after taking a course of treatment, the symptoms have improved, after taking 3 courses of treatment, 36 people recovered, 9 people markedly effective, 3 effective, 2 invalid, there is always The efficiency is 96%.

Claims (5)

1. A method of treating hyperlipidemia medicine, characterized in that: the main component of the ratio by parts by weight:

30-40 copies of Alisma, Capillaris and Pueraria, 25-30 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 15-25 parts of dried tangerine peel, platycodon grandiflorum and whole melon, each of which is 10 and 10 -15 servings, 5-10 parts of Hemp and Rhubarb;

The specific steps of the preparation method are as follows:

a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;

b. According to the formula ratio, the diarrhea, mycelium, puerarin, seaweed, kelp, chaihu, white peony, turmeric, tangerine peel, platycodon grandiflorum, whole melon stalk, smashed stalk, dodder, and hemp seed are added 5-7 times by weight. Cold water is placed in a decocting machine for 60-90 minutes, first boiled with a fire, then simmered for 1-2 hours with a simmer, filtered to obtain a filtrate b;

c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

2. A traditional Chinese medicine for treating hyperlipemia according to claim 1, wherein:

35-40 parts of Alisma, Capillaris and Pueraria, 25-30 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 15-20 parts of dried tangerine peel, platycodon grandiflorum and whole melon, each of which is 10 -15 servings, 5-10 parts of Hemp and Rhubarb.

3. A traditional Chinese medicine for treating hyperlipemia according to claim 1, wherein:

There are 36 copies of Alisma, Yinchen and Pueraria, 28 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 17 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 13 parts of sclerotium and dodder, each of which is hemp, 7 parts of each rhubarb.

4. A method for preparing a traditional Chinese medicine for treating hyperlipemia, characterized in that: the specific steps are:

a. According to the formula ratio, the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;

b. According to the formula ratio, the diarrhea, mycelium, puerarin, seaweed, kelp, chaihu, white peony, turmeric, tangerine peel, platycodon grandiflorum, whole melon stalk, smashed stalk, dodder, and hemp seed are added 5-7 times by weight. Cold water is placed in a decocting machine for 60-90 minutes, first boiled with a fire, then simmered for 1-2 hours with a simmer, filtered to obtain a filtrate b;

c. The filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.

The method for preparing a traditional Chinese medicine for treating hyperlipemia according to claim 4, characterized in that: adding cold water: 6-7 times cold water; soaking time: 80-90 minutes; simmering time: 1.5- 2 hours.