WO2017045249A1 - Médicament chinois traditionnel pour le traitement de l'hyperlipidémie et procédé de préparation associé - Google Patents

Médicament chinois traditionnel pour le traitement de l'hyperlipidémie et procédé de préparation associé Download PDF

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Publication number
WO2017045249A1
WO2017045249A1 PCT/CN2015/093326 CN2015093326W WO2017045249A1 WO 2017045249 A1 WO2017045249 A1 WO 2017045249A1 CN 2015093326 W CN2015093326 W CN 2015093326W WO 2017045249 A1 WO2017045249 A1 WO 2017045249A1
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WO
WIPO (PCT)
Prior art keywords
parts
chinese medicine
traditional chinese
seaweed
rhubarb
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Application number
PCT/CN2015/093326
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English (en)
Chinese (zh)
Inventor
刘燕
刘衍素
Original Assignee
济南正骐生物科技有限公司
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Publication of WO2017045249A1 publication Critical patent/WO2017045249A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/884—Alismataceae (Water-plantain family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

Definitions

  • the invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine for treating hyperlipemia and a preparation method thereof.
  • Hyperlipidemia is a disease in which plasma cholesterol, triglyceride, and low-density lipoprotein levels are elevated and high-density lipoprotein is too low in a systemic metabolic disorder caused by various causes.
  • drugs for lowering blood fat There are currently three types of commonly used drugs for lowering blood fat. : clofibrate, niacin, statins. Commonly used drugs are simvastatin, lovastatin and the like. These drugs have a certain effect on lipid-lowering, but they are prone to attack after stopping the drug.
  • the liver and kidney function should be reviewed regularly during the medication, because these drugs are irritating to the gastrointestinal tract and have damage to the liver and kidney, and should not be taken for a long time.
  • the invention discloses a traditional Chinese medicine for treating high-lipemia with safe and effective, good curative effect and a preparation method thereof for solving the existing problems.
  • the medicine adopts pure Chinese medicine, has no side effects, has high cure rate, quick effect, is not easy to relapse, and has simple preparation method.
  • a traditional Chinese medicine for treating hyperlipemia which is mainly distributed in parts by weight:
  • the distribution ratio of the traditional Chinese medicine is mainly 35-40 parts by weight of Alisma, Capillaris, Pueraria, 25-30 parts of seaweed, kelp, Bupleurum, peony and turmeric. 15-20 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 10-15 parts of each of the broken bones and dodders, 5-10 parts of hemp and rhubarb.
  • the optimal ratio of the traditional Chinese medicine to the distribution is: by weight, 36 parts of Maizhao, Yinchen and Pueraria, 28 parts of seaweed, kelp, Bupleurum, white peony and turmeric, respectively, and tangerine peel, There are 17 servings of platycodon grandiflorum and whole melon, 13 parts of sclerotium and scorpion, and 7 parts of hemp and rhubarb.
  • the specific preparation method is as follows:
  • the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;
  • the diarrhea, mycelium, puerarin, seaweed, kelp, chaihu, white peony, turmeric, tangerine peel, platycodon grandiflorum, whole melon stalk, smashed stalk, dodder, and hemp seed are added 5-7 times by weight.
  • Cold water is placed in a decocting machine for 60-90 minutes, first boiled with a fire, then simmered for 1-2 hours with a simmer, filtered to obtain a filtrate b;
  • the filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.
  • Alisma can reduce low-density lipoprotein in blood, increase high-density lipoprotein, regulate blood lipids; Yinchen lowers blood fat, reduces arteriosclerosis, reduces visceral fat deposition, reduces cholesterol content in aortic wall; Pueraria has hypolipidemic effect; seaweed And Kunbu, soft and firm, reduce blood fat; Bupleurum liver and gallbladder, lowering blood fat, regulating gastrointestinal function; white sputum sweating dehumidification, reducing water molecules in the body, and can promote fat decomposition, inhibit fat synthesis; turmeric qi Activating blood, lowering blood fat; Chen Pi Li biliary, can lower serum cholesterol, reduce and improve aortic sclerosis; platycodon blood sugar and blood lipids, and can remove sputum, sputum, pus and other sticky substances; It has a laxative effect and lowers blood fat; bone shredding, dodder silk supplements the liver and kidney yang, enhances the function of
  • the invention has the beneficial effects that the invention provides a traditional Chinese medicine for treating hyperlipemia and a preparation method thereof, and the traditional Chinese medicine has the functions of relieving liver and gallbladder, relieving laxative, enhancing liver and intestine functions, and effectively treating hyperlipemia disease. .
  • the invention selects pure natural Chinese medicinal materials, has wide drug source, low price, safe and effective, convenient administration, short treatment course, good curative effect and no toxicity.
  • a traditional Chinese medicine for treating hyperlipemia which is mainly distributed in parts by weight:
  • the specific preparation method is as follows:
  • the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;
  • the filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.
  • a traditional Chinese medicine for treating hyperlipemia mainly in proportion to parts by weight:
  • the specific preparation method is as follows:
  • the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;
  • the filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.
  • a traditional Chinese medicine for treating hyperlipemia mainly in proportion to parts by weight:
  • Alisma There are 40 copies of Alisma, Yinchen and Pueraria, 30 parts of seaweed, kelp, Bupleurum, white peony and turmeric, 25 parts of dried tangerine peel, platycodon grandiflorum and whole melon, 15 parts of sclerotium and medlar, each of which is hemp, 10 parts of each rhubarb.
  • the specific preparation method is as follows:
  • the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;
  • the filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.
  • a traditional Chinese medicine for treating hyperlipemia mainly in proportion to parts by weight:
  • the specific preparation method is as follows:
  • the rhubarb is crushed through a 100 mesh sieve to prepare a powder a;
  • the filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.
  • a traditional Chinese medicine for treating hyperlipemia which is mainly distributed in parts by weight:
  • the specific preparation method is as follows:
  • the rhubarb is crushed through a 100 mesh sieve to prepare a powder for use;
  • the filtrate b and the powder a are stirred and mixed uniformly, dried, and passed through a 100 mesh sieve to form a pellet.
  • Treatment results a total of 50 patients, each taking 10 patients, after taking a course of treatment, the symptoms have improved, after taking 3 courses of treatment, 36 people recovered, 9 people markedly effective, 3 effective, 2 invalid, there is always The efficiency is 96%.

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La présente invention concerne un médicament chinois traditionnel pour le traitement de l'hyperlipémie, le médicament chinoise traditionnel comprenant les composants suivants en parties en poids : 30 à 40 parties de Rhizoma alismatis, 30 à 40 parties d'armoise en arbre, 30 à 40 parties de la racine de la vigne kudzu, 25 à 30 parties d'algues, 25 à 30 parties de varech, 25 à 30 parties de Radix bupleuri, 25 à 30 parties de Radix angelicae, 25 à 30 parties de Radix curcumae, 15 à 25 parties de Pericarpium citri reticulatae, 15 à 25 parties de Platycodon grandiflorum, 15 à 25 parties de Fructus trichosanthis, 10 à 15 parties de Rhizoma drynariae, 10 à 15 parties de graines de cuscute chinoise, 5 à 10 parties de Fructus cannabis, et 5 à 10 parties de rhubarbe préparée.
PCT/CN2015/093326 2015-09-15 2015-10-30 Médicament chinois traditionnel pour le traitement de l'hyperlipidémie et procédé de préparation associé WO2017045249A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510583709.3 2015-09-15
CN201510583709.3A CN105079708A (zh) 2015-09-15 2015-09-15 一种治疗高脂血的中药及其制备方法

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Publication Number Publication Date
WO2017045249A1 true WO2017045249A1 (fr) 2017-03-23

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111631395A (zh) * 2020-06-24 2020-09-08 王有伟 降脂养心保健油茶

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105079708A (zh) * 2015-09-15 2015-11-25 济南正骐生物科技有限公司 一种治疗高脂血的中药及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104855979A (zh) * 2015-04-22 2015-08-26 劲膳美生物科技股份有限公司 降血脂非全营养配方食品
CN105079708A (zh) * 2015-09-15 2015-11-25 济南正骐生物科技有限公司 一种治疗高脂血的中药及其制备方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104855979A (zh) * 2015-04-22 2015-08-26 劲膳美生物科技股份有限公司 降血脂非全营养配方食品
CN105079708A (zh) * 2015-09-15 2015-11-25 济南正骐生物科技有限公司 一种治疗高脂血的中药及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CEN, YIBEI ET AL.: "Current Research of TCM in Treating Hyperlipoidemia", HEBEI JOURNAL OF TRADITIONAL CHINESE MEDICINE, vol. 33, no. 1, 31 January 2011 (2011-01-31) *
ZHEN, ZHIGANG ET AL.: "TCM Clinical Research Progress of Hyperlipoidemia", HEBEI JOURNAL OF TRADITIONAL CHINESE MEDICINE, vol. 33, no. 8, 31 August 2011 (2011-08-31) *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111631395A (zh) * 2020-06-24 2020-09-08 王有伟 降脂养心保健油茶

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