WO2017031683A1 - Traditional chinese medicine for treating hypertensive heart disease and preparation method therefor - Google Patents

Traditional chinese medicine for treating hypertensive heart disease and preparation method therefor Download PDF

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WO2017031683A1
WO2017031683A1 PCT/CN2015/087993 CN2015087993W WO2017031683A1 WO 2017031683 A1 WO2017031683 A1 WO 2017031683A1 CN 2015087993 W CN2015087993 W CN 2015087993W WO 2017031683 A1 WO2017031683 A1 WO 2017031683A1
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traditional chinese
heart disease
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付双燕
邱程程
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济南正骐生物科技有限公司
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • the invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine for treating hypertensive heart disease and a preparation method thereof.
  • Hypertensive heart disease refers to the progression of hypertension in patients with hypertension. After reaching the second stage of hypertension, there is left ventricular hypertrophy and even heart failure and heart failure, called hypertensive heart disease. Mainly manifested as left heart failure, that is, difficulty breathing, and may be accompanied by chest tightness, palpitations, dizziness, headache, vertigo, tinnitus, insomnia, fatigue and other symptoms. At present, there are many Western medicines for treating hypertensive heart disease, but this disease is not easy to cure. Long-term use of western medicine has side effects. There are also some traditional Chinese medicines for treating hypertensive heart disease, but they all have slower effects and are not satisfactory.
  • the invention provides a traditional Chinese medicine for treating hypertensive heart disease with good curative effect according to the deficiencies of the prior art and a preparation method thereof.
  • the medicine adopts pure Chinese medicine, has no side effects, has high cure rate, good effect, is not easy to relapse, and has simple preparation method.
  • a traditional Chinese medicine for treating hypertensive heart disease the main distribution ratio is: by weight:
  • Raw jaundice 35-45 servings white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum 30-40
  • Ingredients 25-30 parts of ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi and Baiziren, 10-20 parts of Prunella vulgaris and Gastrodia elata.
  • the main medicine is mainly distributed in parts by weight:
  • the optimal ratio of the traditional Chinese medicine to the distribution is: by weight:
  • the specific preparation method is as follows:
  • a Proportionally put medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella vulgaris, Tianma in casserole, add 3-5 times weight Cold water soak 60-90 Minutes, simmer until boiling, simmer for 40-60 minutes, filter to obtain a liquid;
  • the above preparation method is further optimized, and the process parameters are: soaking time 60-70 minutes; simmer boiling time 40-50 minutes.
  • Astragalus does not need to be soaked, and the boiling time should not be too long. In order to ensure its better efficacy, it is added directly after boiling water, and the simmer is made.
  • This medicine is a direct oral medicine, once 150ml, twice a day, usually a course of 5 days, even 3 a course of treatment.
  • Baiziren nourishes heart and soothe the nerves, relieves bowel movements, treats convulsions and insomnia; Prunella vulgaris can treat high blood pressure and has antihypertensive effect; Tianma has analgesia , lowering blood pressure, anti-convulsant effect; the above drugs are used in combination, synergistic effect, with the effect of calming the nerves and strengthening the heart, thus achieving the purpose of treating hypertensive heart disease.
  • the invention provides a traditional Chinese medicine for treating hypertensive heart disease, which has the effects of calming the nerves and calming the heart and reducing blood pressure, and can effectively treat hypertensive heart disease.
  • the invention selects pure natural Chinese medicinal materials, has wide drug source, low price, safe and effective, convenient administration, short treatment course, good curative effect and no toxicity.
  • a traditional Chinese medicine for treating hypertensive heart disease mainly divided into parts by weight:
  • the specific preparation method is as follows:
  • the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella vulgaris, Tianma are placed in the casserole, and 3 times the weight of cold water is added. Soak 60 Minutes, simmer until boiling, simmer for 40 minutes, filter to obtain a liquid;
  • a traditional Chinese medicine for treating hypertensive heart disease mainly divided into parts by weight:
  • the specific preparation method is as follows:
  • the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, and Tianma are placed in the casserole, and 5 times the weight of cold water is added. Soak 90 Minutes, Wuhuo fry until boiling, simmer for 60 minutes, filter to obtain a liquid;
  • a traditional Chinese medicine for treating hypertensive heart disease mainly divided into parts by weight:
  • the specific preparation method is as follows:
  • the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, and Tianma are placed in the casserole, and 4 times the weight of cold water is added. Soak 70 Minutes, simmer until boiling, simmer for 50 minutes, filter to obtain a liquid;
  • a traditional Chinese medicine for treating hypertensive heart disease mainly divided into parts by weight:
  • the specific preparation method is as follows:
  • the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella vulgaris, Tianma are placed in the casserole, and 3 times the weight of cold water is added. Soak 90 Minutes, Wuhuo fry until boiling, simmer for 60 minutes, filter to obtain a liquid;
  • a traditional Chinese medicine for treating hypertensive heart disease mainly divided into parts by weight:
  • the specific preparation method is as follows:
  • the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, and Tianma are placed in the casserole, and 5 times the weight of cold water is added. Soak 60 Minutes, simmer until boiling, simmer for 50 minutes, filter to obtain a liquid;
  • Treatment results A total of 100 patients, each taking 20 patients, after taking a course of treatment, the symptoms have improved, taking medication 3 After the course of treatment, 80 people recovered, 14 were markedly effective, 3 were effective, 3 were ineffective, and the total effective rate was 97%.

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Abstract

A traditional Chinese medicine for treating a hypertensive heart disease and a preparation method therefor. The traditional Chinese medicine is made of the following ingredients in part by weight: 35 to 45 parts of astragalus root, 30 to 40 parts of radix paeoniae alba, 30 to 40 parts of radix ophiopogonis, 30 to 40 parts of prepared rehmannia root, 30 to 40 parts of glossy privet fruit, 25 to 30 parts of ginger processed pinellia, 25 to 30 parts of bamboo shavings, 25 to 30 parts of arisaema cum bile, 25 to 30 parts of Acorus tatarinowii, 25 to 30 parts of polygala root, 25 to 30 parts of platycladi seed, 10 to 20 parts of selfheal, and 10 to 20 parts of gastrodia elata.

Description

一种治疗高血压性心脏病的中药及其制备方法  Traditional Chinese medicine for treating hypertensive heart disease and preparation method thereof 一种治疗高血压性心脏病的中药及其制备方法  Traditional Chinese medicine for treating hypertensive heart disease and preparation method thereof
技术领域 Technical field
本发明属于中药制剂领域,具体涉及一种治疗高血压性心脏病的中药及其制备方法。 The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine for treating hypertensive heart disease and a preparation method thereof.
背景技术 Background technique
高血压性心脏病是指高血压患者随病程进展,达到第二期高血压后,出现左心室肥厚甚至出现心功不全和心力衰竭,称为高血压性心脏病。主要表现为左心衰竭,即呼吸困难,并可伴有胸闷、心悸、头晕、头痛、眼花、耳鸣、失眠、乏力等症状。目前,治疗高血压性心脏病的西药较多,但此病症不易根治,长期服用西药有副作用;也有一些治疗高血压性心脏病的中药,但都见效较慢,效果不理想。 Hypertensive heart disease refers to the progression of hypertension in patients with hypertension. After reaching the second stage of hypertension, there is left ventricular hypertrophy and even heart failure and heart failure, called hypertensive heart disease. Mainly manifested as left heart failure, that is, difficulty breathing, and may be accompanied by chest tightness, palpitations, dizziness, headache, vertigo, tinnitus, insomnia, fatigue and other symptoms. At present, there are many Western medicines for treating hypertensive heart disease, but this disease is not easy to cure. Long-term use of western medicine has side effects. There are also some traditional Chinese medicines for treating hypertensive heart disease, but they all have slower effects and are not satisfactory.
发明内容 Summary of the invention
  本发明根据针对现有技术的不足提供一种治愈效果好的治疗高血压性心脏病的中药及其制备方法。该药物采用纯中药,无副作用,治愈率高,效果好,不易复发,制备方法简单。 The invention provides a traditional Chinese medicine for treating hypertensive heart disease with good curative effect according to the deficiencies of the prior art and a preparation method thereof. The medicine adopts pure Chinese medicine, has no side effects, has high cure rate, good effect, is not easy to relapse, and has simple preparation method.
一种治疗高血压性心脏病的中药,主要成分配比按重量份计为: A traditional Chinese medicine for treating hypertensive heart disease, the main distribution ratio is: by weight:
生黄芪 35-45 份,白芍、麦冬、熟地黄、女贞子各 30-40 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 25-30 份,夏枯草、天麻各 10-20 份。 Raw jaundice 35-45 servings, white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum 30-40 Ingredients: 25-30 parts of ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi and Baiziren, 10-20 parts of Prunella vulgaris and Gastrodia elata.
作为上述技术方案的进一步优选,所述中药主要成分配比按重量份计为: As a further preferred embodiment of the above technical solution, the main medicine is mainly distributed in parts by weight:
生黄芪 35-40 份,白芍、麦冬、熟地黄、女贞子各 30-35 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 25-30 份,夏枯草、天麻各 10-15 份。 35-40 copies of raw scutellaria, white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum 30-35 Ingredients: 25-30 parts of ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, 10-15 parts of Prunella vulgaris and Gastrodia elata.
进一步优化上述技术方案,所述中药主要成分配最佳比按重量份计为: Further optimizing the above technical solution, the optimal ratio of the traditional Chinese medicine to the distribution is: by weight:
生黄芪 38 份,白芍、麦冬、熟地黄、女贞子各 32 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 26 份,夏枯草、天麻各 13 份。 38 parts of raw scutellaria, 32 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinxia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 26 servings, 13 copies of Prunella vulgaris and Gastrodia elata.
根据以上工艺处方,具体制备方法如下: According to the above process prescription, the specific preparation method is as follows:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 3-5 倍重量的冷水浸泡 60-90 分钟,武火煎至沸腾,文火煎煮 40-60 分钟,过滤得药液 a ; a Proportionally put medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella vulgaris, Tianma in casserole, add 3-5 times weight Cold water soak 60-90 Minutes, simmer until boiling, simmer for 40-60 minutes, filter to obtain a liquid;
b 、向砂锅加入 6-7 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 40-60 分钟,过滤得药液 b ; b, add to the casserole 6-7 The water of double weight is subjected to the second boiling. After the fire is simmered to boiling, the scutellaria is added to the boiled liquid in proportion, and simmer for 40-60 minutes to filter the liquid b;
   c 、药液 a 和药夜 b 混合均匀,得药剂。 c, liquid medicine a and drug night b mixed evenly, get the medicine.
进一步优化上述制备方法,工艺参数为:浸泡时间 60-70 分钟;文火煎煮时间 40-50 分钟。 The above preparation method is further optimized, and the process parameters are: soaking time 60-70 minutes; simmer boiling time 40-50 minutes.
黄芪不需浸泡,煎煮时间也不宜过长,为保证其更好的药效,直接水沸腾之后加入,文火熬制。 Astragalus does not need to be soaked, and the boiling time should not be too long. In order to ensure its better efficacy, it is added directly after boiling water, and the simmer is made.
使用方法:本药剂为直接口服药物,一次 150ml ,一天两次,一般 5 天一个疗程,连服 3 个疗程。 How to use: This medicine is a direct oral medicine, once 150ml, twice a day, usually a course of 5 days, even 3 a course of treatment.
药理分析:生黄芪的用量最多,此药可补气强心降压,可发挥其药效有效治疗高血压性心脏病;白芍具有平抑肝阳,养血收阴的功效;熟地黄主治血虚萎黄、心悸怔忡;白芍、熟地黄滋阴补阳,有利于降压;女贞子主治头晕目眩、视物昏花、阴虚发热;姜半夏燥湿化痰,降逆止呕;竹茹具有清热化痰,除烦止呕,惊悸不宁,心烦失眠的作用;胆南星具有抗惊厥、抗心律失常的疗效;石菖蒲具有调节中枢神经系统的作用;远志用于治疗神经衰弱、健忘心悸,与石菖蒲复配使用可用于治疗心气不足、五脏不足等病症;柏子仁养心安神、润肠通便,治惊悸、失眠;夏枯草可治疗高血压,具有降压的功效;天麻具有镇痛,降血压,抗惊厥的作用;上述药物配伍使用,协同作用,具有安神镇静,强心降压的功效,从而达到治疗高血压性心脏病目的。 Pharmacological analysis: the highest dosage of raw jaundice, this medicine can tonify the heart and reduce blood pressure, can exert its efficacy to effectively treat hypertensive heart disease; white peony has the effect of calming liver yang, nourishing blood and yin; rehmannia radix is the main blood Deficiency of wilting, palpitations; white peony root, rehmannia radix tonifying yin and yang, is conducive to blood pressure; female scorpion attending dizziness, dizziness, yin deficiency and fever; ginger semi-summer dampness and phlegm, lowering and stopping vomiting; Clearing away heat and phlegm, in addition to annoying vomiting, convulsions, restlessness, upset and insomnia; bilirubin has anti-convulsion, anti-arrhythmia effect; Shichangpu has the role of regulating the central nervous system; Yuanzhi is used to treat neurasthenia, forgetfulness, It can be used in combination with Shichangpu to treat symptoms such as lack of heart and lack of internal organs. Baiziren nourishes heart and soothe the nerves, relieves bowel movements, treats convulsions and insomnia; Prunella vulgaris can treat high blood pressure and has antihypertensive effect; Tianma has analgesia , lowering blood pressure, anti-convulsant effect; the above drugs are used in combination, synergistic effect, with the effect of calming the nerves and strengthening the heart, thus achieving the purpose of treating hypertensive heart disease.
本发明提供一种治疗高血压性心脏病的中药,具有安神镇静,强心降压的功效,能有效地治疗高血压性心脏病。本发明精选纯天然中药材,药源广泛,价格低,安全有效,给药方便,疗程短,疗效好,无毒性。 The invention provides a traditional Chinese medicine for treating hypertensive heart disease, which has the effects of calming the nerves and calming the heart and reducing blood pressure, and can effectively treat hypertensive heart disease. The invention selects pure natural Chinese medicinal materials, has wide drug source, low price, safe and effective, convenient administration, short treatment course, good curative effect and no toxicity.
具体实施方式 detailed description
实施例 1 Example 1
一种治疗高血压性心脏病的中药,主要成分配比按重量份计: A traditional Chinese medicine for treating hypertensive heart disease, mainly divided into parts by weight:
生黄芪 38 份,白芍、麦冬、熟地黄、女贞子各 32 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 26 份,夏枯草、天麻各 13 份。 38 parts of raw scutellaria, 32 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinxia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 26 servings, 13 copies of Prunella vulgaris and Gastrodia elata.
根据以上工艺处方,具体制备方法如下: According to the above process prescription, the specific preparation method is as follows:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 3 倍重量的冷水浸泡 60 分钟,武火煎至沸腾,文火煎煮 40 分钟,过滤得药液 a ; a Proportionally, the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella vulgaris, Tianma are placed in the casserole, and 3 times the weight of cold water is added. Soak 60 Minutes, simmer until boiling, simmer for 40 minutes, filter to obtain a liquid;
b 、向砂锅加入 6 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 40 分钟,过滤得药液 b ; b. Add 6 times the weight of water to the casserole for the second time. After the fire is simmered to boiling, add the scutellaria to the boiling liquid in proportion, and simmer. 40 minutes, filtered liquid solution b;
   c 、药液 a 和药夜 b 混合均匀,得药剂。 c, liquid medicine a and drug night b mixed evenly, get the medicine.
实施例 2 Example 2
一种治疗高血压性心脏病的中药,主要成分配比按重量份计: A traditional Chinese medicine for treating hypertensive heart disease, mainly divided into parts by weight:
生黄芪 35 份,白芍、麦冬、熟地黄、女贞子各 30 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 25 份,夏枯草、天麻各 10 份。 35 parts of raw scutellaria, 30 parts of white peony root, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 25 servings, 10 copies of Prunella vulgaris and Gastrodia elata.
根据以上工艺处方,具体制备方法如下: According to the above process prescription, the specific preparation method is as follows:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 5 倍重量的冷水浸泡 90 分钟,武火煎至沸腾,文火煎煮 60 分钟,过滤得药液 a ; a Proportionally, the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, and Tianma are placed in the casserole, and 5 times the weight of cold water is added. Soak 90 Minutes, Wuhuo fry until boiling, simmer for 60 minutes, filter to obtain a liquid;
b 、向砂锅加入 7 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 60 分钟,过滤得药液 b ; b. Add 7 times the weight of water to the casserole for the second time. After the fire is simmered until boiling, add the scutellaria to the boiled liquid in proportion and simmer. 60 minutes, filtered liquid solution b;
   c 、药液 a 和药夜 b 混合均匀,得药剂。 c, liquid medicine a and drug night b mixed evenly, get the medicine.
实施例 3 Example 3
一种治疗高血压性心脏病的中药,主要成分配比按重量份计: A traditional Chinese medicine for treating hypertensive heart disease, mainly divided into parts by weight:
生黄芪 45 份,白芍、麦冬、熟地黄、女贞子各 40 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 30 份,夏枯草、天麻各 20 份。 45 parts of raw scutellaria, 40 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinxia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 30 servings, 20 copies of Prunella vulgaris and Gastrodia elata.
根据以上工艺处方,具体制备方法如下: According to the above process prescription, the specific preparation method is as follows:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 4 倍重量的冷水浸泡 70 分钟,武火煎至沸腾,文火煎煮 50 分钟,过滤得药液 a ; a Proportionally, the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, and Tianma are placed in the casserole, and 4 times the weight of cold water is added. Soak 70 Minutes, simmer until boiling, simmer for 50 minutes, filter to obtain a liquid;
b 、向砂锅加入 6 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 50 分钟,过滤得药液 b ; b. Add 6 times the weight of water to the casserole for the second time. After the fire is simmered to boiling, add the scutellaria to the boiling liquid in proportion, and simmer. 50 minutes, filtered liquid solution b;
   c 、药液 a 和药夜 b 混合均匀,得药剂。 c, liquid medicine a and drug night b mixed evenly, get the medicine.
实施例 4 Example 4
一种治疗高血压性心脏病的中药,主要成分配比按重量份计: A traditional Chinese medicine for treating hypertensive heart disease, mainly divided into parts by weight:
生黄芪 40 份,白芍、麦冬、熟地黄、女贞子各 35 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 28 份,夏枯草、天麻各 15 份。 40 parts of raw scutellaria, 35 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 28 servings, 15 copies of Prunella vulgaris and Gastrodia elata.
根据以上工艺处方,具体制备方法如下: According to the above process prescription, the specific preparation method is as follows:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 3 倍重量的冷水浸泡 90 分钟,武火煎至沸腾,文火煎煮 60 分钟,过滤得药液 a ; a Proportionally, the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella vulgaris, Tianma are placed in the casserole, and 3 times the weight of cold water is added. Soak 90 Minutes, Wuhuo fry until boiling, simmer for 60 minutes, filter to obtain a liquid;
b 、向砂锅加入 6 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 40 分钟,过滤得药液 b ; b. Add 6 times the weight of water to the casserole for the second time. After the fire is simmered to boiling, add the scutellaria to the boiling liquid in proportion, and simmer. 40 minutes, filtered liquid solution b;
   c 、药液 a 和药夜 b 混合均匀,得药剂。 c, liquid medicine a and drug night b mixed evenly, get the medicine.
实施例 5 Example 5
一种治疗高血压性心脏病的中药,主要成分配比按重量份计: A traditional Chinese medicine for treating hypertensive heart disease, mainly divided into parts by weight:
生黄芪 42 份,白芍、麦冬、熟地黄、女贞子各 32 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 28 份,夏枯草、天麻各 18 份。 42 parts of raw scutellaria, 32 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinxia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 28 servings, 18 copies of Prunella vulgaris and Gastrodia elata.
根据以上工艺处方,具体制备方法如下: According to the above process prescription, the specific preparation method is as follows:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 5 倍重量的冷水浸泡 60 分钟,武火煎至沸腾,文火煎煮 50 分钟,过滤得药液 a ; a Proportionally, the medicinal materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, Pinellia ternata, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, and Tianma are placed in the casserole, and 5 times the weight of cold water is added. Soak 60 Minutes, simmer until boiling, simmer for 50 minutes, filter to obtain a liquid;
b 、向砂锅加入 6 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 60 分钟,过滤得药液 b ; b. Add 6 times the weight of water to the casserole for the second time. After the fire is simmered to boiling, add the scutellaria to the boiling liquid in proportion, and simmer. 60 minutes, filtered liquid solution b;
   c 、药液 a 和药夜 b 混合均匀,得药剂。 c, liquid medicine a and drug night b mixed evenly, get the medicine.
本发明临床观察的结果如下: The results of clinical observation of the present invention are as follows:
  痊愈:临床症状完全消失或基本消失; Healed: the clinical symptoms completely disappeared or disappeared;
显效:临床症状大部分好转或明显好转; Significant effect: most of the clinical symptoms improved or significantly improved;
无效;临床症状无明显改善,症状如前,效果不明显。 Invalid; no significant improvement in clinical symptoms, symptoms before, the effect is not obvious.
治疗结果 :共 100 例患者,每实施例各 20 人服用,服药一个疗程后,症状均有所好转,服药 3 个疗程后, 80 人痊愈, 14 人显效, 3 人有效, 3 人无效,总有效率为 97 %。 Treatment results: A total of 100 patients, each taking 20 patients, after taking a course of treatment, the symptoms have improved, taking medication 3 After the course of treatment, 80 people recovered, 14 were markedly effective, 3 were effective, 3 were ineffective, and the total effective rate was 97%.

Claims (5)

1. 一种治疗高血压性心脏病的中药,其特征是:主要成分配比按重量份计: 1. A traditional Chinese medicine for treating hypertensive heart disease, characterized in that: the main distribution ratio is by weight:
生黄芪 35-45 份,白芍、麦冬、熟地黄、女贞子各 30-40 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 25-30 份,夏枯草、天麻各 10-20 份;35-45 parts of raw scutellaria, 30-40 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 25-30 parts, 10-20 parts of Prunella vulgaris and Gastrodia elata;
其制备方法具体步骤如下:The specific steps of the preparation method are as follows:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 3-5 倍重量的冷水浸泡 60-90 分钟,武火煎至沸腾,文火煎煮 40-60 分钟,过滤得药液 a ;a, according to the proportion of raw materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, Tianma into the casserole, plus Soak in cold water of 3-5 times weight for 60-90 minutes, fry until boiling, simmer for 40-60 minutes, filter to obtain liquid medicine a;
b 、向砂锅加入 6-7 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 40-60 分钟,过滤得药液 b ;b. Add 6-7 times of water to the casserole for the second time. After the fire is simmered to boiling, add the scutellaria to the boiling liquid in proportion, and simmer for 40-60. Minutes, filtered liquid solution b;
c 、药液 a 和药夜 b 混合均匀,得药剂。c, liquid medicine a and drug night b mixed evenly, get the medicine.
2. 根据权利要求 1 所述的一种治疗高血压性心脏病的中药,其特征是:主要成分配比按重量份计: 2. A traditional Chinese medicine for treating hypertensive heart disease according to claim 1, characterized in that the main distribution ratio is in parts by weight:
生黄芪 35-40 份,白芍、麦冬、熟地黄、女贞子各 30-35 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 25-30 份,夏枯草、天麻各 10-15 份。35-40 parts of raw scutellaria, 30-35 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 25-30 parts, 10-15 parts of Prunella vulgaris and Gastrodia elata.
3. 根据权利要求 1 所述的一种治疗高血压性心脏病的中药,其特征是:主要成分配比按重量份计:3. The traditional Chinese medicine for treating hypertensive heart disease according to claim 1, wherein the main distribution ratio is in parts by weight:
生黄芪 38 份,白芍、麦冬、熟地黄、女贞子各 32 份,姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁各 26 份,夏枯草、天麻各 13 份。38 parts of raw scutellaria, 32 parts of white peony, Ophiopogon japonicus, Rehmannia glutinosa, and Ligustrum lucidum, ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren 26 1 part of Prunella vulgaris and Gastrodia elata.
4. 一种治疗高血压性心脏病的中药的制备方法,其特征是:具体步骤为:4. A method for preparing a traditional Chinese medicine for treating hypertensive heart disease, characterized in that: the specific steps are:
a 、按比例将药材生白芍、麦冬、熟地黄、女贞子、姜半夏、竹茹、胆南星、石菖蒲、远志、柏子仁、夏枯草、天麻放到砂锅中,加 3-5 倍重量的冷水浸泡 60-90 分钟,武火煎至沸腾,文火煎煮 40-60 分钟,过滤得药液 a ;a, according to the proportion of raw materials such as white peony, Ophiopogon japonicus, Rehmannia glutinosa, Ligustrum lucidum, ginger Pinellia, Zhuru, Dannanxing, Shichangpu, Yuanzhi, Baiziren, Prunella, Tianma into the casserole, plus Soak in cold water of 3-5 times weight for 60-90 minutes, fry until boiling, simmer for 40-60 minutes, filter to obtain liquid medicine a;
b 、向砂锅加入 6-7 倍重量的水进行第二次煎煮,武火煎至沸腾后,按比例将黄芪加入沸腾的药液中,文火煎煮 40-60 分钟,过滤得药液 b ;b. Add 6-7 times of water to the casserole for the second time. After the fire is simmered to boiling, add the scutellaria to the boiling liquid in proportion, and simmer for 40-60. Minutes, filtered liquid solution b;
c 、将药液 a 和药夜 b 混合均匀,得药剂。c. Mix the liquid medicine a and the medicine night b to obtain the medicine.
5. 根据权利要求 4 所述的一种治疗高血压性心脏病的中药的制备方法,其特征是:浸泡时间 60-70 分钟;文火煎煮时间 40-50 分钟。  The method for preparing a traditional Chinese medicine for treating hypertensive heart disease according to claim 4, characterized in that: the soaking time is 60-70 minutes; the simmering time is simmered 40-50 minutes.
PCT/CN2015/087993 2015-08-25 2015-08-25 Traditional chinese medicine for treating hypertensive heart disease and preparation method therefor WO2017031683A1 (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703698A (en) * 2009-11-18 2010-05-12 秦跃山 Chinese medicament for treating heart disease
CN101991816A (en) * 2010-11-12 2011-03-30 李奕星 Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases
CN103055126A (en) * 2013-01-17 2013-04-24 张晓兰 Chinese medicinal herb composition for treating hypertensive heart disease and preparation method thereof
CN104510927A (en) * 2013-10-07 2015-04-15 青岛联合创新技术服务平台有限公司 Traditional Chinese medicine formula for treating hypertension
CN105031350A (en) * 2015-07-30 2015-11-11 济南正骐生物科技有限公司 Traditional Chinese medicine for treating hypertensive heart disease and preparation method for traditional Chinese medicine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703698A (en) * 2009-11-18 2010-05-12 秦跃山 Chinese medicament for treating heart disease
CN101991816A (en) * 2010-11-12 2011-03-30 李奕星 Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases
CN103055126A (en) * 2013-01-17 2013-04-24 张晓兰 Chinese medicinal herb composition for treating hypertensive heart disease and preparation method thereof
CN104510927A (en) * 2013-10-07 2015-04-15 青岛联合创新技术服务平台有限公司 Traditional Chinese medicine formula for treating hypertension
CN105031350A (en) * 2015-07-30 2015-11-11 济南正骐生物科技有限公司 Traditional Chinese medicine for treating hypertensive heart disease and preparation method for traditional Chinese medicine

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