CN111491651A - Traditional Chinese medicine composition and preparation process and application thereof - Google Patents
Traditional Chinese medicine composition and preparation process and application thereof Download PDFInfo
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Abstract
A Chinese medicinal composition comprises (by weight parts) flos Lonicerae 60-260, radix Angelicae sinensis 30-150, Coicis semen 15-90, semen Persicae 15-75, radix Peucedani 15-75, pericarpium Citri Tangerinae 30-150, and fructus Aurantii Immaturus 15-75. The composition has effects of clearing away heat and toxic materials, promoting blood circulation, dispelling blood stasis, loosening bowel to relieve constipation, resolving hard mass, relieving swelling, expelling pus, and removing toxic substances, and can be used for treating various carbuncle and acne. The preparation process of the composition is simple, the conditions are mild, and the composition is suitable for industrial batch production.
Description
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and relaxing bowel, and a preparation process and application thereof.
Abscess and pus are acute suppurative diseases of body surface, limbs and internal organs, and are a kind of toxic sore. Carbuncle is caused by muscle, red and swollen, which is mostly due to yang syndrome, deep-rooted carbuncle is caused by bone, flat, collapsed and dark-colored, which is mostly due to yin syndrome. Carbuncle and cellulitis can be manifested by swelling, burning out, pain and pus formation. Modern medicine explains that it is pyogenic inflammation caused by bacterial infection of the hair follicles and sebaceous glands of the skin, the pathogenic bacterium being staphylococcus.
Among them, abscess and deep-rooted carbuncle in the internal organs are called internal abscess, and the three thirty-three internal abscess symptoms are recorded in the treatise on the disease-related syndromes: the "interior abscess" refers to abscess in the stomach, triple energizer, intestinal abscess, small intestinal abscess, cardiac abscess, liver abscess, spleen abscess, lung abscess, kidney abscess, etc. due to improper diet, irregular cold and heat, cold-qi flowing in the interior, or in the chest diaphragm, or in the intestine and stomach, cold turning into blood, blood-qi remaining, and cold attacking, accumulation and stagnation, and heat affecting into pus. The disease is often accompanied by symptoms such as aversion to cold, fever, thirst and the like, the disease generally takes clearing heat and removing toxicity as a treatment principle, but no traditional Chinese medicine formula with good efficacy exists at present.
Disclosure of Invention
Therefore, the technical problem to be solved by the present invention is how to provide a Chinese medicinal composition capable of effectively relieving the symptoms in the background art, and a preparation process and an application thereof.
In order to solve the technical problems, the technical scheme of the invention is as follows:
the invention provides a traditional Chinese medicine composition which comprises, by weight, 60-260 parts of honeysuckle, 30-150 parts of angelica sinensis, 15-90 parts of pearl barley, 15-75 parts of peach kernels, 15-75 parts of radix peucedani, 30-150 parts of pericarpium citri reticulatae and 15-75 parts of immature bitter orange.
Preferably, the composition further comprises 10-70 parts of fructus evodiae by weight.
Preferably, the composition comprises, by weight, 100-200 parts of honeysuckle, 70-100 parts of angelica, 50-80 parts of pearl barley, 35-50 parts of peach kernel, 35-50 parts of radix peucedani, 75-100 parts of dried orange peel and 40-60 parts of immature bitter orange.
Preferably, the composition comprises 240 parts by weight of honeysuckle, 120 parts by weight of angelica, 75 parts by weight of pearl barley, 60 parts by weight of peach kernel, 60 parts by weight of radix peucedani, 120 parts by weight of dried orange peel and 45 parts by weight of immature bitter orange.
Preferably, the composition comprises, by weight, 100-200 parts of honeysuckle, 70-100 parts of angelica, 50-80 parts of pearl barley, 35-50 parts of peach kernel, 35-50 parts of radix peucedani, 75-100 parts of dried orange peel, 40-60 parts of immature bitter orange and 30-50 parts of fructus evodiae.
Preferably, the composition comprises 240 parts by weight of honeysuckle, 120 parts by weight of angelica, 75 parts by weight of pearl barley, 60 parts by weight of peach kernel, 60 parts by weight of radix peucedani, 120 parts by weight of dried orange peel, 45 parts by weight of immature bitter orange and 45 parts by weight of fructus evodiae.
The invention also provides a process for preparing the traditional Chinese medicine composition, which comprises the following steps:
s1, weighing the raw materials in proportion, mixing uniformly, and soaking with water;
s2, decocting the soaked raw materials;
s3, filtering the dregs to obtain the medicinal juice.
Preferably, in the step S1, the mass ratio of the total mass of the raw materials to the water is 1: 2.3-10, and the soaking time is 20-40 min.
Preferably, in the step S2, the decoction process is to boil the soaked materials with water and then decoct the materials at the temperature of 100-115 ℃ for 60-90 min.
The invention also provides application of the traditional Chinese medicine composition in preparation of medicines for clearing heat and removing toxicity, promoting blood circulation to remove blood stasis and relaxing bowel.
Compared with the prior art, the technical scheme of the invention has the following advantages:
(1) the traditional Chinese medicine composition comprises, by weight, 60-260 parts of honeysuckle, 30-150 parts of Chinese angelica, 15-90 parts of coix seeds, 15-75 parts of peach seeds, 15-75 parts of radix peucedani, 30-150 parts of dried orange peels and 15-75 parts of immature bitter oranges. The components are mutually matched according to the compatibility of monarch, minister, assistant and guide, have good effects of clearing heat and removing toxicity, promoting blood circulation and removing blood stasis, and loosening bowel to relieve constipation, can be used for treating various viscera carbuncle pus, and has the effects of resolving hard mass and reducing swelling, expelling pus and removing toxicity, curing acne and the like.
(2) The traditional Chinese medicine composition can also comprise 10-70 parts of fructus evodiae by weight, and for patients with cold-fluid syndrome or body deficiency cold and serious body cold evil (generally, the deficiency cold in the middle-upper jiao is taken as the main part), the fructus evodiae has the effects of dispelling cold and relieving pain, so the composition can be added with the fructus evodiae to play a role in properly protecting the patients from aggravating body cold.
(3) The process for preparing the traditional Chinese medicine composition has simple steps and mild conditions, is suitable for industrial batch production, does not need residue recovery after decoction, and is convenient to take.
In order that the present disclosure may be more readily and clearly understood, reference is now made to the following detailed description of the embodiments of the present disclosure taken in conjunction with the accompanying drawings, in which
Fig. 1 is a process flow chart of the preparation of the Chinese medicinal composition according to the embodiment of the present invention.
Example 1
The embodiment provides a traditional Chinese medicine composition, which can be used for relieving symptoms of various viscera and carbuncle-abscess, and has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relaxing bowel and the like.
The traditional Chinese medicine composition comprises 60g of honeysuckle, 30g of angelica, 15g of pearl barley, 15g of peach kernel, 15g of radix peucedani, 30g of dried orange peel and 15g of immature bitter orange.
The present invention also provides a process for preparing a Chinese medicinal composition, which comprises the following steps:
s1, weighing the components in proportion, mixing uniformly, and soaking in 1800ml of water for 20 min.
S2, boiling the soaked materials with strong fire, adjusting to slow fire, and decocting at 105 deg.C for 90 min.
S3, filtering to remove dregs of a decoction to obtain 800ml of medicinal juice.
In the traditional Chinese medicine composition, the honeysuckle has the functions of dispelling wind heat and clearing away blood toxin, and has obvious effects on various heat diseases such as fever, eruption, macula, sore and carbuncle caused by heat toxin, sore throat and the like; radix Angelicae sinensis has effects in replenishing blood, regulating blood, moistening dryness, smoothing intestine, and enhancing immunity; the Coicis semen has effects of promoting diuresis, invigorating spleen, eliminating arthralgia, clearing heat, and expelling pus; semen Persicae has effects of promoting blood circulation, dispelling blood stasis, loosening bowel to relieve constipation, and relieving cough and asthma; bupleuri radix has effects of lowering qi, eliminating phlegm, dispelling pathogenic wind and clearing heat; pericarpium Citri Tangerinae has effects of regulating qi-flowing, invigorating spleen, eliminating dampness and eliminating phlegm; the immature bitter orange has the effects of stagnation, fullness and pain, constipation and diarrhea and dysentery with tenesmus, and the effects are mutually matched and cooperated after the components are decocted, so that the effect of remarkably enhancing the drug effect is achieved.
The traditional Chinese medicine composition can be used for preparing medicines for clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and relaxing bowel.
Example 2
The embodiment provides a traditional Chinese medicine composition, which can be used for relieving symptoms of various viscera and carbuncle-abscess, and has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relaxing bowel and the like.
The traditional Chinese medicine composition comprises 260g of honeysuckle, 150g of angelica sinensis, 90g of coix seeds, 75g of peach kernels, 75g of radix peucedani, 150g of pericarpium citri reticulatae and 75g of immature bitter oranges, and the traditional Chinese medicine composition further comprises 70g of fructus evodiae, has the effects of dispelling cold, relieving pain, calming the adverse-rising energy and preventing vomiting, and is suitable for people with cold body.
The embodiment also provides a process for preparing the traditional Chinese medicine composition for clearing heat and removing toxicity, and activating blood and removing stasis, which comprises the following steps:
s1, weighing the components in proportion, mixing uniformly, and soaking for 40min by 1800ml of water.
S2, boiling the soaked materials with strong fire, adjusting to slow fire, and decocting at 115 deg.C for 60 min.
S3, filtering to remove dregs of a decoction and obtaining 650ml of medicine juice.
The traditional Chinese medicine composition can be used for preparing medicines for clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and relaxing bowel.
Example 3
The embodiment provides a traditional Chinese medicine composition, which can be used for relieving symptoms of various viscera and carbuncle-abscess, and has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relaxing bowel and the like.
The traditional Chinese medicine composition comprises 240g of honeysuckle, 120g of angelica sinensis, 75g of coix seeds, 60g of peach kernels, 60g of radix peucedani, 120g of pericarpium citri reticulatae and 45g of immature bitter oranges, and the traditional Chinese medicine composition further comprises 45g of fructus evodiae, has the effects of dispelling cold, relieving pain, calming the adverse-rising energy and preventing vomiting, and is suitable for people with cold body.
The present invention also provides a process for preparing a Chinese medicinal composition, which comprises the following steps:
s1, weighing the components in proportion, mixing uniformly, and soaking in 1800ml of water for 30 min.
S2, boiling the soaked materials with strong fire, adjusting to slow fire, and decocting at 110 deg.C for 80 min.
S3, filtering to remove dregs of a decoction to obtain 700ml of medicinal juice.
The traditional Chinese medicine composition can be used for preparing medicines for clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and relaxing bowel.
Example 4
The embodiment provides a traditional Chinese medicine composition, which can be used for relieving symptoms of various viscera and carbuncle-abscess, and has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relaxing bowel and the like.
The traditional Chinese medicine composition comprises 180g of honeysuckle, 80g of angelica sinensis, 40g of coix seeds, 30g of peach kernels, 45g of radix peucedani, 60g of dried orange peels and 40g of immature bitter oranges, and the traditional Chinese medicine composition also comprises 10g of fructus evodiae, has the effects of dispelling cold, relieving pain, calming the adverse-rising energy and preventing vomiting, and is suitable for people with cold body.
The embodiment also provides a process for preparing the traditional Chinese medicine composition for clearing heat and removing toxicity, and activating blood and removing stasis, which comprises the following steps:
s1, weighing the components in proportion, mixing uniformly, and soaking in 1700ml of water for 35 min.
S2, boiling the soaked materials with strong fire, adjusting to slow fire, and decocting at 110 deg.C for 70 min.
S3, cooling the solid-liquid mixture obtained in the step S2 after decoction, and filtering to obtain 650ml of decoction.
The traditional Chinese medicine composition can be used for preparing medicines for clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and relaxing bowel.
Examples 5 to 10
Examples 5 to 10 provide the Chinese medicinal compositions in the ratios shown in table 1, and the preparation processes of the Chinese medicinal compositions in the ratios are the same as those in examples 1 to 3.
TABLE 1
Examples of the experiments
153 acnes caused by red and severe heat toxin in decades of 2008-2018 are selected, among 153 patients, 93 male patients and 60 female patients are selected, the age of the patients is between 15 and 28 years, and the acnes caused by red and severe heat toxin in all patients are clinically manifested by red and swollen acnes, induration and large-area continuous outbreak. Clinical efficacy observation was performed using the Chinese medicinal composition described in example 1.
The treatment mode comprises the following steps: the Chinese medicinal composition juice is taken three times in the morning, at noon and at night, 200ml of the Chinese medicinal composition juice is taken every time, and the Chinese medicinal composition juice is taken for one week.
The judgment standard of the curative effect is as follows: and (3) curing: complete disappearance of symptoms and signs; the effect is shown: most symptoms and signs disappear after treatment; and (4) invalidation: symptoms and signs are not alleviated and tend to be even more severe.
And (3) counting the curative effect: 153 patients treated by the traditional Chinese medicine composition for clearing heat and removing dryness in the embodiment 1 are cured by 45 patients, 88 patients with obvious effect and 20 patients with no effect, the effective rate can reach 86.9 percent, and the traditional Chinese medicine composition is a traditional Chinese medicine composition with good efficacy for clearing heat and removing toxicity, promoting blood circulation and removing blood stasis.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.
Claims (10)
- A traditional Chinese medicine composition is characterized by comprising, by weight, 60-260 parts of honeysuckle, 30-150 parts of angelica sinensis, 15-90 parts of pearl barley, 15-75 parts of peach kernels, 15-75 parts of radix peucedani, 30-150 parts of pericarpium citri reticulatae and 15-75 parts of immature bitter orange.
- The traditional Chinese medicine composition of claim 1, further comprising 10-70 parts by weight of fructus evodiae.
- The traditional Chinese medicine composition as claimed in claim 1, wherein the composition comprises, by weight, 100-200 parts of honeysuckle, 70-100 parts of angelica, 50-80 parts of pearl barley, 35-50 parts of peach kernel, 35-50 parts of peucedanum root, 75-100 parts of dried orange peel and 40-60 parts of immature bitter orange.
- The traditional Chinese medicine composition of claim 1, wherein the composition comprises, by weight, 240 parts of honeysuckle, 120 parts of angelica sinensis, 75 parts of coix seed, 60 parts of peach kernel, 60 parts of radix peucedani, 120 parts of dried orange peel and 45 parts of immature bitter orange.
- The traditional Chinese medicine composition as claimed in claim 2, wherein the composition comprises, by weight, 100-200 parts of honeysuckle, 70-100 parts of angelica, 50-80 parts of pearl barley, 35-50 parts of peach kernel, 35-50 parts of peucedanum root, 75-100 parts of dried orange peel, 40-60 parts of immature bitter orange and 30-50 parts of fructus evodiae.
- The traditional Chinese medicine composition of claim 2, wherein the composition comprises 240 parts of honeysuckle, 120 parts of angelica, 75 parts of pearl barley, 60 parts of peach kernel, 60 parts of radix peucedani, 120 parts of dried orange peel, 45 parts of immature bitter orange and 45 parts of fructus evodiae.
- A process for preparing the Chinese medicinal composition of any one of claims 1 to 6, comprising the steps of:s1, weighing the raw materials in proportion, mixing uniformly, and soaking with water;s2, decocting the soaked raw materials;s3, filtering the dregs to obtain the medicinal juice.
- The preparation process of the traditional Chinese medicine composition according to claim 7, wherein in the step S1, the mass ratio of the total mass of the raw materials to the water is 1: 2.3-10, and the soaking time is 20-40 min.
- The preparation process of the Chinese medicinal composition as claimed in claim 8, wherein the decocting step in step S2 comprises boiling the soaked materials with water, and decocting at 100-115 deg.C for 60-90 min.
- The use of the Chinese medicinal composition of any one of claims 1-6 in the preparation of a medicament for clearing heat and toxic materials, promoting blood circulation to remove blood stasis, and loosening bowel to relieve constipation.
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| CN103182036A (en) * | 2011-12-28 | 2013-07-03 | 杜万伟 | Agent-I curing soup for intestinal carbuncle |
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| CN101156938A (en) * | 2007-09-01 | 2008-04-09 | 彭书珍 | A formulation for treating appendicitis |
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| CN103182036A (en) * | 2011-12-28 | 2013-07-03 | 杜万伟 | Agent-I curing soup for intestinal carbuncle |
Non-Patent Citations (5)
| Title |
|---|
| 刘学华: "痈疡消剂的组方配伍特点", 《山东中医学院学报》 * |
| 廖卫顺等: "中西医结合治疗急性阑尾炎32例", 《中国中医急症》 * |
| 徐冰等: "浅析金银花的药理作用与临床应用", 《黑龙江科技信息》 * |
| 潘纯: "治疗寻常痤疮的古今方剂用药规律研究", 《中国优秀博硕士学位论文全文数据库（硕士）医药卫生科技辑》 * |
| 黄川: "《华佗神方》", 30 November 2010, 广州出版社 * |
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Address after: 518000 Guangdong city of Shenzhen province Futian District Futian District, three Lunuode financial center building on the west side of 32B Applicant after: Dedao Health Management Co.,Ltd. Applicant after: Liu Zhijie Address before: 518000 Guangdong city of Shenzhen province Futian District Futian District, three Lunuode financial center building on the west side of 32B Applicant before: SHENZHEN DEDAO HEALTH MANAGEMENT Co.,Ltd. Applicant before: Liu Zhijie |
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Application publication date: 20200804 |
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