CN106620271A - Traditional Chinese medicine composition for treating actinophytosis of milk cows - Google Patents
Traditional Chinese medicine composition for treating actinophytosis of milk cows Download PDFInfo
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- CN106620271A CN106620271A CN201611137494.3A CN201611137494A CN106620271A CN 106620271 A CN106620271 A CN 106620271A CN 201611137494 A CN201611137494 A CN 201611137494A CN 106620271 A CN106620271 A CN 106620271A
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Classifications
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Abstract
The invention discloses a traditional Chinese medicine composition for treating actinophytosis of milk cows, belonging to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is characterized by containing the following components in parts by weight: 25-45 parts of aspongopus, 55-75 parts of herba violae, 40-60 parts of rhizoma pleionis, 20-40 parts of Picris japonica, 60-80 parts of cottonrose hibiscus, 40-60 parts of Commelina paludosa, 20-40 parts of leaf of alderleaf sida, 60-80 parts of semipinnated brake herb, 60-80 parts of sida rhombifolia, 20-40 parts of Japanese milkwort herb, 15-25 parts of Japanese cayratia herb, 25-45 parts of all-grass of Tangut dragonhead, 40-60 parts of radix adenophorae, 15-30 parts of honey-fried licorice and 5-15 parts of radix platycodonis. The traditional Chinese medicine composition disclosed by the invention has the efficacies of clearing away the heat and toxic materials, relieving swelling and pain, removing the slough, promoting the growth of tissue regeneration and converging sores and wounds. The traditional Chinese medicine composition has safe pesticide effect and is environmentally friendly, free of pollution, very high in curing rate and suitable for being widely popularized and used in the production of animal husbandry.
Description
Technical field
The invention belongs to technical field of Chinese veterinary medicine, in particular, belongs to one kind and treats the actinomycotic Chinese medicine group of milch cow
Compound.
Background technology
Milk lumpy-jaw is called bigjaw in prior art, is a kind of chronic infectious disease that Actinomyces bovises cause, its
It is characterized as that local skin, muscle occur hard swelling, ulceration, wound and do not recover for a long time for principal character.The milk lumpy-jaw cause of disease：Cause of disease
It is a kind of bar for not moving, not formed spore for Actinomyces bovis (Yi Shi unwrapping wire bacterium, Lin Shi Actinobacillus and suppurative bacterium)
Bacterium, actinomycetes are invaded after infected cattle deep tissue, are caused leukocyte infiltration and connective tissue proliferation, and then are developed into tumor sample and go to live in the household of one's in-laws on getting married
Biology-actinomycoma.Milk Actinomyces bovis epidemiology：Primary disease mainly encroaches on cattle, with 2-5 year young age cattle most easily ill, puts
The pathogen of line bacterium cause of disease is present in contaminated soil, feedstuff and drinking-water, mainly the band prickle by being polluted by actinomycetes
Plant or apparatus are stabbed oral mucosa and skin and are infected.
The actinomycotic main symptom of milch cow：The rising of infected cattle body temperature, loss of appetite, be commonly at infected cattle jawbone occur swelling formed
Solid lump.Occur difficult due to breathing, swallowing and chewing, so occurring becoming thin rapidly.There are pain, later stage skin at swollen portion's initial stage
Skin suppuration ulceration, granulation tissue protrudes from skin surface in mushroom, and it is prolonged not to form the puss of fistula outflow clear yellow viscous
More, have a strong impact on and give milk.The actinomycotic laboratory diagnosiss of milch cow：The sick clinical symptoms and pathological changes are more special, it is easy to make
Go out diagnosis.Pus can be diluted with aquae destillata if necessary, find out sulfur granule, be cleaned on rearmounted microscope slide, plus one and drip 10-
15% liquor kalii caustici, covers microscope slide and exerts oneself rubbing and pressure, puts low power lens low light level microscopy, it is seen that characteristic Flos Chrysanthemi shape truffle, and four
There is the radiation club-like body that bent photosensitiveness is stronger week, bacterial species can be made a definite diagnosis with Gram’s staining.Prior art treats milch cow
Actinomycosis, adopt antibiotic therapy primary disease mostly, are also easy to produce drug resistance using antibiotic in a large number for a long time, there is drug residue, control
Therapeutic effect has much room for improvement.
The content of the invention
The present invention gives one kind and treats the actinomycotic Chinese medicine composition of milch cow to efficiently solve above technical problem
Thing.
One kind of the present invention treats the actinomycotic Chinese medicine composition of milch cow, it is characterised in that include by weight：Nine is fragrant
Worm 25-45 parts, Herba Violae 55-75 parts, Pseudobulbus cremastrae seu pleiones 40-60 parts, Herba Elephantopi Mollis 20-40 parts, Hibisci Mutabilis 60-80 parts, big bud duck plantar
Careless 40-60 parts, Folium sidae alnifoliae 20-40 parts, Herba Pteridis Semipinnatae 60-80 parts, white back of the body Radix sidae acutae 60-80 parts, Herba Polygalae Japonicae 20-40 part, crow hold back prunus mume (sieb.) sieb.et zucc.
15-25 parts, Tang Gute ultramarine 25-45 parts, Radix Adenophorae (Radix Glehniae) 40-60 parts, Radix Glycyrrhizae (processed with honey) 15-30 parts, Radix Platycodoniss 5-15 parts.
The actinomycotic Chinese medicine composition for the treatment of milch cow in accordance with the above, it is preferable that include by weight：Aspongopuss 25
Part, 55 parts of Herba Violae, 40 parts of Pseudobulbus cremastrae seu pleiones, 20 parts of Herba Elephantopi Mollis, 60 parts of Hibisci Mutabilis, 40 parts of Commelina paludosa, 20 parts of Folium sidae alnifoliae, half
60 parts of side flag, the white back of the body 60 parts of Radix sidae acutae, 20 parts of Herba Polygalae Japonicae, that crow holds back 15 parts of prunus mume (sieb.) sieb.et zucc., 25 parts of Tang Gute ultramarine, 40 parts of Radix Adenophorae (Radix Glehniae), processed with honey is sweet
Careless 15 parts, 5 parts of Radix Platycodoniss.
The actinomycotic Chinese medicine composition for the treatment of milch cow in accordance with the above, it is preferable that include by weight：Aspongopuss 45
Part, 75 parts of Herba Violae, 60 parts of Pseudobulbus cremastrae seu pleiones, 40 parts of Herba Elephantopi Mollis, 80 parts of Hibisci Mutabilis, 60 parts of Commelina paludosa, 40 parts of Folium sidae alnifoliae, half
80 parts of side flag, the white back of the body 80 parts of Radix sidae acutae, 40 parts of Herba Polygalae Japonicae, that crow holds back 25 parts of prunus mume (sieb.) sieb.et zucc., 45 parts of Tang Gute ultramarine, 60 parts of Radix Adenophorae (Radix Glehniae), processed with honey is sweet
Careless 30 parts, 15 parts of Radix Platycodoniss.
The actinomycotic Chinese medicine composition for the treatment of milch cow in accordance with the above, it is preferable that include by weight：Aspongopuss 37
Part, 67 parts of Herba Violae, 50 parts of Pseudobulbus cremastrae seu pleiones, 28 parts of Herba Elephantopi Mollis, 70 parts of Hibisci Mutabilis, 50 parts of Commelina paludosa, 30 parts of Folium sidae alnifoliae, half
67 parts of side flag, the white back of the body 64 parts of Radix sidae acutae, 30 parts of Herba Polygalae Japonicae, that crow holds back 17 parts of prunus mume (sieb.) sieb.et zucc., 38 parts of Tang Gute ultramarine, 48 parts of Radix Adenophorae (Radix Glehniae), processed with honey is sweet
Careless 20 parts, 9 parts of Radix Platycodoniss.
The actinomycotic Chinese medicine composition for the treatment of milch cow in accordance with the above, it is preferable that include by weight：Aspongopuss 32
Part, 62 parts of Herba Violae, 48 parts of Pseudobulbus cremastrae seu pleiones, 24 parts of Herba Elephantopi Mollis, 66 parts of Hibisci Mutabilis, 46 parts of Commelina paludosa, 26 parts of Folium sidae alnifoliae, half
62 parts of side flag, the white back of the body 60 parts of Radix sidae acutae, 38 parts of Herba Polygalae Japonicae, that crow holds back 20 parts of prunus mume (sieb.) sieb.et zucc., 32 parts of Tang Gute ultramarine, 44 parts of Radix Adenophorae (Radix Glehniae), processed with honey is sweet
Careless 18 parts, 5 parts of Radix Platycodoniss.
Each component property of medicine effect in the Chinese medicine composition of present invention treatment milch cow defence line bacterium disease：
Aspongopuss：Nature and flavor：Salty, temperature.Return through：Returns spleen, liver and kidney channel.Effect：Regulating QI to relieve pain, warming middle-JIAO tonifying YANG.Cure mainly：To putting
Line bacterium has very high inhibition killing action.
Herba Violae：Nature and flavor：Bitter, acrid, cold.Return through：Enter the heart, Liver Channel.Effect：Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Cure mainly：Skin ulcer
General edema with yellowish skin poison, scrofula subcutaneous nodule.
Pseudobulbus cremastrae seu pleiones：Nature and flavor：It is sweet, micro-pungent, cold.Return through：Return liver, spleen channel.Effect：Heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.Cure mainly：Carbuncle
Cellulitis furunculosis, laryngopharynx swelling and pain, aphtha of the mouth and tongue, Chuan Yellow toxic swellings, venom.
Herba Elephantopi Mollis：Nature and flavor：It is bitter, cold.Return through：Return liver, kidney, stomach, small intestine meridian.Effect：Anti inflammation and heat resolution, liver protection dampness removing.Cure mainly：
Antiinflammatory, diuresis, detumescence.
Hibisci Mutabilis：Nature and flavor：It is pungent, flat.Return through：Attach to the lung and stomach meridians.Effect：Removing pathogenic heat from blood and toxic substance from the body, detumescence toxin expelling, eliminating stasis to stop pain.It is main
Control：Conjunctival congestion and swelling pain, aphtha of the mouth and tongue, early application energy reducing swelling and alleviating pain promote swelling to absorb.Middle and late stage has evacuation of pus ulceration into pus person
Work(.
Commelina paludosa：Nature and flavor：It is sweet, light, cold.Return through：GUIXIN, liver, spleen, large intestine channel.Effect：Inducing diuresis to remove edema, heat clearing away solution
Poison, cooling blood for hemostasis.Cure mainly：Laryngopharynx swelling and pain, ulcerative carbuncle furunculosis.
Folium sidae alnifoliae：Nature and flavor：It is bitter, pungent, be slightly cold.Return through：GUIXIN, lung meridian.Function with cure mainly；Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.It is main
Control：The diseases such as laryngopharynx swelling and pain, carbuncle sore tumefacting virus, damp-heat dysentery, Yellow subcutaneous ulcers.
Herba Pteridis Semipinnatae：Nature and flavor：It is bitter, pungent, cool.Return through：Return liver, large intestine channel.Effect：Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, hemostasis life
Flesh.Cure mainly：Skin infection swelling, snake venom are bitten, traumatic injury causes blood stasis swelling, traumatic hemorrhage, furuncle.
White back of the body Radix sidae acutae：Nature and flavor：It is sweet, light, cool.Return through：Return lung, Liver Channel.Effect：Clearing away heat-damp and promoting diuresis, evacuation of pus detumescence.Cure mainly：
Detumescence and apocenosis, convergence granulation promoting.Effect：Dispersing swelling and dissipating binds, removing toxic substances and promoting tissue regeneration.Cure mainly：Control scrofula tuberculosis, carbuncle sore tumefacting virus.
Herba Polygalae Japonicae：Nature and flavor：It is tepor, pungent.Return through：Return liver, stomach.Effect：Promoting blood circulation to remove blood stasis, removing toxic substances pain relieving.Cure mainly：Swelling throat
Bitterly, carbuncle sore tumefacting virus.
Crow holds back prunus mume (sieb.) sieb.et zucc.：Nature and flavor：It is sour, bitter, cold.Return through：GUIXIN, liver, stomach.Effect：Heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, diuresis.It is main
Control：Laryngopharynx swelling and pain, furunculosis swell and ache.
Tang Gute ultramarine：Nature and flavor：It is bitter, cold.Effect：Stomach function regulating is soothing the liver, the heat of liver heat removing stomach.Cure mainly：Ulcer, gastritis, hepatitis.
Radix Adenophorae (Radix Glehniae)：Nature and flavor：Sweet, slight bitter.Return through：Attach to the lung and stomach meridians.Effect：Clearing away heat and nourishing YIN, strengthening the spleen stomach invigorating, nourishing YIN for benefiting the kidney.It is main
Control：Deficient fever, impairment of yin cough caused by dryness, thirsty and dry pharynx.
Radix Glycyrrhizae (processed with honey)：Nature and flavor：It is flat, sweet.Return through：Return 12 warps.Effect：QI invigorating and in, relax the property of medicine, emergency analgesic therapy, solution
The work(of poison.Cure mainly：Weakness of the spleen and stomach, expelling phlegm for arresting cough.Radix Glycyrrhizae (processed with honey) strengthens nourishing the lung to arrest cough, invigorating the spleen and replenishing QI effect, each medicine in mitigation side
The property of medicine, lowers toxic and side effects.
Radix Platycodoniss：Nature and flavor：It is bitter, pungent, flat.Return through：Return lung Jing.Effect：Open lung qi dispersing gas, eliminating the phlegm evacuation of pus.Cure mainly：Cough due to lung-heat,
Laryngopharynx swelling and pain.The many compatibility Radix Platycodoniss of throat disease, it is up with priming.
Present invention treatment milk lumpy-jaw composition treatment principle：
Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, putrefaction-removing granulation-promoting, sore close up.
Fang Xie：With Aspongopuss, Herba Violae, Pseudobulbus Cremastrae Seu Pleioness as principal agent in side, principal agent nature and flavor are all hardship, trembling with fear is longer than heat clearing away solution
Poison, mass dissipating and swelling eliminating.Not only heat clearing away but also can detoxify, control because of the lumpy-jaw local swelling caused by evil poison invasion, it is swollen and do not burst and
The long disease do not received of bursting；With Herba Elephantopi Mollis, Hibisci Mutabilis, Commelina paludosa, Folium sidae alnifoliae, Herba Pteridis Semipinnatae, white back of the body Hemerocallis citrina Baroni sth. made by twisting, Herba Polygalae Japonicae, supplemented by
Medicine, assists principal agent to strengthen the pyretic toxicity for purifying the blood point, and dissipation pyretic toxicity stores the blood stasis swelling formed caused by carbuncle, plays removing pathogenic heat from blood and toxic substance from the body, invigorates blood circulation
The effect of pain relieving, expelling pus and promoting granulation healing open sore part；With Tang Gute ultramarine, Radix Adenophorae (Radix Glehniae) as adjuvant drug rise QI and blood and adjust, strengthening QI of middle-JIAO controls prolonged illness
Deficiency of vital energy insufficiency of blood caused by body void, weak hypoimmunity of becoming thin, strong carcass improves resistance；It is all to make medicine reconcile with Radix Glycyrrhizae (processed with honey)
Medicine, relaxes the property of medicine.With Radix Platycodoniss as priming, draw the up through infected cattle affected part of all medicines.
The usage and dosage of Chinese medicine composition of the present invention：Powder, by each 2g/kg of milch cow body weight, stomach tube is thrown and is taken, and daily one
It is secondary, typically it is used in conjunction seven to ten days.
The Chinese medicine composition of the present invention uses the maximum area of antibiotics with existing western medical treatment milk lumpy-jaw
It is not to change the outdated ideas of medication on veterinary clinic, long-term abuse of antibiotics class Drug therapy cattle defence line bacterium disease can cause domestic animal
Non-specific immunity is low, and induction produces multiple antibiotic resistant strain, and medicine is in, and carcass is interior to be remained, and harm people's food meat, breast are pacified
Entirely.Less use antibiotic medicine, use Chinese veterinary drug preparation instead because Chinese veterinary drug preparation mostly have antiviral, antibacterium, anti-stress,
Improve the effect of carcass immunity substitute antibiotics class medicine.
What Chinese medicine was taken is personalized compound preparation, has specific aim to disease, Effective Component of Chinese Medicine in therapeutic process
Diversification, antibacterial, virus are difficult to produce drug resistance to it so that Chinese medicine has significantly excellent in terms for the treatment of infectious disease
Gesture, will not produce drug residue again, and Excreta does not cause environmental pollution to soil, water source.
The present invention constitutes compound preparation according to motherland's Traditional Chinese medical theory, preferred agents, scientific compatibility according to optimum proportioning.
With reference to new formulation technology, released by veterinary medicine industry, in the actinomycotic clinical type of milch cow and the cure rate of chronic type
It is improved.
The beneficial effect of the present invention and prior art：The present invention pharmaceutical composition overcome the deficiencies in the prior art and
The low shortcoming of cure rate.There is provided a kind of evident in efficacy, instant effect, cure high, safe and reliable treatment milch cow it is actinomycotic in
Drug composition formula.
The Chinese prescription reasonable cost of the present invention is low, and medical material is natural pollution-free, drug residue free after infected cattle medication, does not have
Off-drug period, the edible meat of people, dairy products are safe from harm.The Chinese medicine composition of the present invention has heat-clearing and toxic substances removing, reducing swelling and alleviating pain, dispels
Necrotic tissue and promoting muscle growing, sore close up.Verified with reference to modern inspection technology over the course for the treatment of, determined curative effect, short treating period, instant effect,
Without recurrence.
Specific embodiment
Preferred implementation 1
The actinomycotic Chinese medicine composition for the treatment of milch cow of this specific embodiment, parts by weights includes：25 parts of Aspongopuss,
55 parts of Herba Violae, 40 parts of Pseudobulbus cremastrae seu pleiones, 20 parts of Herba Elephantopi Mollis, 60 parts of Hibisci Mutabilis, 40 parts of Commelina paludosa, 20 parts of Folium sidae alnifoliae, one side of something
60 parts of flag, white 60 parts of Radix sidae acutae of the back of the body, 20 parts of Herba Polygalae Japonicae, crow hold back 15 parts of prunus mume (sieb.) sieb.et zucc., 25 parts of Tang Gute ultramarine, 40 parts of Radix Adenophorae (Radix Glehniae), Radix Glycyrrhizae (processed with honey)
15 parts, 5 parts of Radix Platycodoniss.
Preparation method
Step one：By 25 grams of Aspongopuss, 55 grams of Herba Violae, 40 grams of Pseudobulbus cremastrae seu pleiones, 20 grams of Herba Elephantopi Mollis, 60 grams of Hibisci Mutabilis, big
40 grams of luxuriant Herba Commelinae, 20 grams of Folium sidae alnifoliae, 60 grams of Herba Pteridis Semipinnatae, white 60 grams of Radix sidae acutae of the back of the body, 20 grams of Herba Polygalae Japonicae, crow hold back 15 grams of prunus mume (sieb.) sieb.et zucc., Tang's Gu
Powder in pulverizer is sent in stirring, mixing in 25 grams of special ultramarine, 40 grams of Radix Adenophorae (Radix Glehniae), 15 grams of Radix Glycyrrhizae (processed with honey), 5 grams of input blenders of Radix Platycodoniss
It is broken, the Chinese medicine composition after crushing is fitted in multi-function extractor, add the water relative to 6 times of its quality amount, to boil 3 little
When, steam pressure is 0.6Mpa process, filters, and obtains the first filtrate and filtering residue；By the filtering residue of acquisition add again relative to
The water of 5 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, be filtrated to get the second filtrate and filtering residue；By first
Filtrate and the second filtrate merge, and concentration removes moisture and obtains dry cream；
Step 2：Crushed using super-fine powder mill, less than 30 microns acquisition Chinese medicine micropowders are crushed to, by what is prepared
Compositionss are put in valve bag or seal standby in container.
This compositions is taken out when using, is washed open with boiled water by gavaging administration after stirring, according to infected cattle weighing machine
After calculating dosage, by gavaging administration once a day, 5-10 days are used in conjunction.Or according to the upper of present embodiment Chinese medicine composition
It is straight to ill domestic animal by stomach tube with Chinese medicinal decoction is obtained after frying pan infusion after proportion relation is stated by Chinese medicine composition mixing immersion
Tap into row to gavage.
Preferred implementation 2
The actinomycotic Chinese medicine composition for the treatment of milch cow of this specific embodiment, parts by weights includes：45 parts of Aspongopuss,
75 parts of Herba Violae, 60 parts of Pseudobulbus cremastrae seu pleiones, 40 parts of Herba Elephantopi Mollis, 80 parts of Hibisci Mutabilis, 60 parts of Commelina paludosa, 40 parts of Folium sidae alnifoliae, one side of something
80 parts of flag, white 80 parts of Radix sidae acutae of the back of the body, 40 parts of Herba Polygalae Japonicae, crow hold back 25 parts of prunus mume (sieb.) sieb.et zucc., 45 parts of Tang Gute ultramarine, 60 parts of Radix Adenophorae (Radix Glehniae), Radix Glycyrrhizae (processed with honey)
30 parts, 15 parts of Radix Platycodoniss.
Preparation method
Step one：By 45 grams of Aspongopuss, 75 grams of Herba Violae, 60 grams of Pseudobulbus cremastrae seu pleiones, 40 grams of Herba Elephantopi Mollis, 80 grams of Hibisci Mutabilis, big
60 grams of luxuriant Herba Commelinae, 40 grams of Folium sidae alnifoliae, 80 grams of Herba Pteridis Semipinnatae, white 80 grams of Radix sidae acutae of the back of the body, 40 grams of Herba Polygalae Japonicae, crow hold back 25 grams of prunus mume (sieb.) sieb.et zucc., Tang's Gu
Powder in pulverizer is sent in stirring, mixing in 45 grams of special ultramarine, 60 grams of Radix Adenophorae (Radix Glehniae), 30 grams of Radix Glycyrrhizae (processed with honey), 15 grams of input blenders of Radix Platycodoniss
It is broken, the Chinese medicine composition after crushing is fitted in multi-function extractor, add the water relative to 6 times of its quality amount, to boil 3 little
When, steam pressure is 0.6Mpa process, filters, and obtains the first filtrate and filtering residue；By the filtering residue of acquisition add again relative to
The water of 5 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, be filtrated to get the second filtrate and filtering residue；By first
Filtrate and the second filtrate merge, and concentration removes moisture and obtains dry cream；
Step 2：Crushed using super-fine powder mill, less than 30 microns acquisition Chinese medicine micropowders are crushed to, by what is prepared
Compositionss are put in valve bag or seal standby in container.
This compositions is taken out when using, is washed open with boiled water by gavaging administration after stirring, according to infected cattle weighing machine
After calculating dosage, by gavaging administration once a day, 5-10 days are used in conjunction.Or according to the upper of present embodiment Chinese medicine composition
It is straight to ill domestic animal by stomach tube with Chinese medicinal decoction is obtained after frying pan infusion after proportion relation is stated by Chinese medicine composition mixing immersion
Tap into row to gavage.
Preferred implementation 3
The actinomycotic Chinese medicine composition for the treatment of milch cow of this specific embodiment, parts by weights includes：37 parts of Aspongopuss,
67 parts of Herba Violae, 50 parts of Pseudobulbus cremastrae seu pleiones, 28 parts of Herba Elephantopi Mollis, 70 parts of Hibisci Mutabilis, 50 parts of Commelina paludosa, 30 parts of Folium sidae alnifoliae, one side of something
67 parts of flag, white 64 parts of Radix sidae acutae of the back of the body, 30 parts of Herba Polygalae Japonicae, crow hold back 17 parts of prunus mume (sieb.) sieb.et zucc., 38 parts of Tang Gute ultramarine, 48 parts of Radix Adenophorae (Radix Glehniae), Radix Glycyrrhizae (processed with honey)
20 parts, 9 parts of Radix Platycodoniss.
Preparation method
Step one：By 37 grams of Aspongopuss, 67 grams of Herba Violae, 50 grams of Pseudobulbus cremastrae seu pleiones, 28 grams of Herba Elephantopi Mollis, 70 grams of Hibisci Mutabilis, big
50 grams of luxuriant Herba Commelinae, 30 grams of Folium sidae alnifoliae, 67 grams of Herba Pteridis Semipinnatae, white 64 grams of Radix sidae acutae of the back of the body, 30 grams of Herba Polygalae Japonicae, crow hold back 17 grams of prunus mume (sieb.) sieb.et zucc., Tang's Gu
Powder in pulverizer is sent in stirring, mixing in 38 grams of special ultramarine, 48 grams of Radix Adenophorae (Radix Glehniae), 20 grams of Radix Glycyrrhizae (processed with honey), 9 grams of input blenders of Radix Platycodoniss
It is broken, the Chinese medicine composition after crushing is fitted in multi-function extractor, add the water relative to 6 times of its quality amount, to boil 3 little
When, steam pressure is 0.6Mpa process, filters, and obtains the first filtrate and filtering residue；By the filtering residue of acquisition add again relative to
The water of 5 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, be filtrated to get the second filtrate and filtering residue；By first
Filtrate and the second filtrate merge, and concentration removes moisture and obtains dry cream；
Step 2：Crushed using super-fine powder mill, less than 30 microns acquisition Chinese medicine micropowders are crushed to, by what is prepared
Compositionss are put in valve bag or seal standby in container.
This compositions is taken out when using, is washed open with boiled water by gavaging administration after stirring, according to infected cattle weighing machine
After calculating dosage, by gavaging administration once a day, 5-10 days are used in conjunction.Or according to the upper of present embodiment Chinese medicine composition
It is straight to ill domestic animal by stomach tube with Chinese medicinal decoction is obtained after frying pan infusion after proportion relation is stated by Chinese medicine composition mixing immersion
Tap into row to gavage.
Preferred implementation 4
The actinomycotic Chinese medicine composition for the treatment of milch cow of this specific embodiment, parts by weights includes：32 parts of Aspongopuss,
62 parts of Herba Violae, 48 parts of Pseudobulbus cremastrae seu pleiones, 24 parts of Herba Elephantopi Mollis, 66 parts of Hibisci Mutabilis, 46 parts of Commelina paludosa, 26 parts of Folium sidae alnifoliae, one side of something
62 parts of flag, white 60 parts of Radix sidae acutae of the back of the body, 38 parts of Herba Polygalae Japonicae, crow hold back 20 parts of prunus mume (sieb.) sieb.et zucc., 32 parts of Tang Gute ultramarine, 44 parts of Radix Adenophorae (Radix Glehniae), Radix Glycyrrhizae (processed with honey)
18 parts, 5 parts of Radix Platycodoniss.
Preparation method
Step one：By 32 grams of Aspongopuss, 62 grams of Herba Violae, 48 grams of Pseudobulbus cremastrae seu pleiones, 24 grams of Herba Elephantopi Mollis, 66 grams of Hibisci Mutabilis, big
46 grams of luxuriant Herba Commelinae, 26 grams of Folium sidae alnifoliae, 62 grams of Herba Pteridis Semipinnatae, white 60 grams of Radix sidae acutae of the back of the body, 38 grams of Herba Polygalae Japonicae, crow hold back 20 grams of prunus mume (sieb.) sieb.et zucc., Tang's Gu
Powder in pulverizer is sent in stirring, mixing in 32 grams of special ultramarine, 44 grams of Radix Adenophorae (Radix Glehniae), 18 grams of Radix Glycyrrhizae (processed with honey), 5 grams of input blenders of Radix Platycodoniss
It is broken, the Chinese medicine composition after crushing is fitted in multi-function extractor, add the water relative to 6 times of its quality amount, to boil 3 little
When, steam pressure is 0.6Mpa process, filters, and obtains the first filtrate and filtering residue；By the filtering residue of acquisition add again relative to
The water of 5 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, be filtrated to get the second filtrate and filtering residue；By first
Filtrate and the second filtrate merge, and concentration removes moisture and obtains dry cream；
Step 2：Crushed using super-fine powder mill, less than 30 microns acquisition Chinese medicine micropowders are crushed to, by what is prepared
Compositionss are put in valve bag or seal standby in container.
This compositions is taken out when using, is washed open with boiled water by gavaging administration after stirring, according to infected cattle weighing machine
After calculating dosage, by gavaging administration once a day, 5-10 days are used in conjunction.Or according to the upper of present embodiment Chinese medicine composition
It is straight to ill domestic animal by stomach tube with Chinese medicinal decoction is obtained after frying pan infusion after proportion relation is stated by Chinese medicine composition mixing immersion
Tap into row to gavage.
Concrete test
Experimental animal：Actinomycosis infected cattle 45 in clinical data, (age 3-9 year, body weight 110-380kg) course of disease exists
In 7-10 days, body weight, age, body condition it is identical with comparability, be randomly divided into 3 groups.
Trial drug：This composition medicine experimental group is respectively adopted, the preferred embodiment for the present invention 1, preferred implementation
2nd, the Chinese medicine powder prepared by preferred implementation 4, takes orally：By each 2g/kg of milch cow body weight, once a day, it is used in conjunction
Seven to ten days.
| Experiment group | Case load (head) | Treatment number (head) | Cure number (head) | Cure rate (%) |
| Test 1 group | 13 | 13 | 12 | 92.3 |
| Test 2 groups | 23 | 23 | 22 | 95.6 |
| Test 3 groups | 9 | 9 | 8 | 88.8 |
Result of the test：One group for the treatment of 13 is tested, cures 12, cure rate 92.3%；Two groups of treatments 23 are tested, is cured
22, cure rate 95.6%；Three groups of treatments 9 are tested, cures 8, cure rate 88.8%.
Contrast test
Experimental animal：Actinomycosis infected cattle 46 in clinical data, are randomly divided into 2 groups of (age 2-7 year, body weight 110-
390kg) course of disease 8-12 days, body weight, age, body condition it is identical with comparability.
Trial drug：This composition medicine, the compositionss powder prepared using the preferred embodiment for the present invention 1, by milch cow
Body weight 2g/kg, takes orally, and one time a day, is used in conjunction 7-10 days.Matched group, (commercially available prod, penicillin 800,000 is single for penicillin, streptomycin
Position, the unit of streptomycin 1,000,000), by 5000 units of milch cow/kg；Streptomycin, by milch cow 12mg/kg, intramuscular injection, penicillin is every
Day 3 times, it is used in conjunction 6-9 days；2 times a day for streptomycin, is used in conjunction 3-4 days.
| Experiment group | Morbidity number (head) | Treatment number (head) | Cure number (head) | Effective number (head) |
| This compositions group | 23 | 23 | 22 | 23 |
| Penicillin and streptomycin group | 23 | 23 | 20 | 22 |
Result of the test；Present composition experimental group, altogether treatment 23, healing 22, cure rate 95.6%, obvious effective rate
100%；Penicillin, streptomycin matched group experimental therapy 23, cure 20, and cure rate is 86.9%, and obvious effective rate is 95.6%,
Cure 1 in infected cattle, recurrence is seen again after first quarter moon.This compositions group is higher than matched group cure rate by 8.7%, and obvious effective rate is high by 4.4%.
The situation of change of blood middle leukocytes
Experimental animal：Actinomycetes infected cattle 2, collection infected cattle blood before test, determines the average phase of blood middle leukocytes
Closely, as contrast test foundation, it was demonstrated that two groups of infected cattle inflammatory reaction are identical with comparability.
Trial drug：This compositions group, from compositionss powder prepared by preferred implementation 1, takes orally：By milch cow body weight
Every time 2g/kg, once a day, is used in conjunction seven to ten days.Matched group, penicillin, streptomycin (commercially available prod, the unit of penicillin 800,000,
The unit of streptomycin 1,000,000), by 5000 units of milch cow/kg；Streptomycin, by milch cow 12mg/kg, intramuscular injection, penicillin daily 3
It is secondary, it is used in conjunction 5-9 days；2 times a day for streptomycin, is used in conjunction 3-4 days.
Test method：Before infected cattle medication, collection infected cattle blood send laboratory blood examination, checks the average of blood middle leukocytes
Number, and record.After infected cattle medication, respectively laboratory blood examination is sent in the 4th day, the 8th day collection infected cattle blood, check white thin in blood
The average of born of the same parents, the meansigma methodss for checking blood middle leukocytes sum on the 12nd day, and Record Comparison.
Result of the test：Above-mentioned two groups of ill domestic animals in test initial stage blood total white blood cellses apparently higher than normal value, using this
Combination group continuous use is after 8 days, the close normal value of total white blood cellses in blood；Matched group is because administration time prolongation, actinomycetes
Drug resistance is produced to antibiotic, was started matched group drug effect from the 5th day and is gradually weakened, total white blood cellses fall after rise and slow down.
This compositions group after medicine after the 12nd day, recover to normal value by the meansigma methodss of ill domestic animal blood middle leukocytes sum：9
×109/L；After medicine after the 12nd day, the meansigma methodss of ill domestic animal blood middle leukocytes sum are matched group：13×109/L.Can more than
To prove, in treatment lumpy-jaw, the composition effect of the present invention is better than matched group.Test criterion：Healthy cow
Blood middle leukocytes mean+SD：9.41±2.13×109/L。
Milk yield comparing result
By test data as can be seen that test group of the present invention improves milk yield higher than penicillin, streptomycin matched group, milch cow
Daily milk yield increases respectively 1kg, 1kg, 2kg, 5kg.Drug residue can be produced using antibiotic, by national regulation antibiosis is used
After extract for treating, it is necessary to abandon milk phase and off-drug period, so milk of matched group milch cow is discarded during this can not eat.The present invention
The complete pure Chinese medicine composition of Chinese medicine composition, will not occur in animal body drug residue, it is ensured that milk safety, green non-pollution.
| Time (my god) | Experimental group of the present invention | Penicillin and streptomycin matched group |
| 1-3 | 21kg | 20kg |
| 4-6 | 24kg | 23kg |
| 7-9 | 26kg | 24kg |
| 10-12 | 36kg | 31kg |
The test of above each group can be seen that the Chinese medicine composition of the present invention and compare matched group drug effect substantially, in therapeutic process
Middle combination modern times inspection technology verified, determined curative effect, short treating period, instant effect, without recurrence.
Test medical record 1
Certain raising dairy cattle field is seen a doctor, and poultry raiser reacts this in the recent period 2 cattle, occurs swelling at cervical region or lower jaw, disease
Cattle pain is uneasy.
Clinical examination and diagnosis：Infected cattle body temperature raises, in intermittent fever, conjunctiva flushing, loss of appetite, the swelling of lower jaw position,
Skin has the cracking mouth for being about 2 centimetres, and in mushroom skin surface is protruded from, and flows out yellow and sticky puss, and what is had has no
Pus, the visible fly in wound is attached to position of festering.
Treatment：From compositionss powder prepared by the preferred embodiment for the present invention 2,3 infected cattles are adopted and gavage administration,
By per kilogram of body weight 2g dosage once a day, 7 to 10 days are used in conjunction；Medication rear infected cattle affected part swelling in 5 days or so is disappeared, pain relief；
Rear observation infected cattle is festered and start gradually to heal at portion within 13 days or so；Follow-up after January has no recurrence.
Test medical record 2
Certain raising dairy cattle field is seen a doctor, and poultry raiser reacts this in the recent period 1 cattle, hard swelling occurs at cervical region and lower jaw.
Clinical examination and diagnosis：Infected cattle body temperature raises, has suppurated in intermittent fever, conjunctiva flushing, loss of appetite, lower jaw part
Ulceration, in mushroom skin surface is protruded from, and flows out yellow and sticky puss.
Treatment：From compositionss powder prepared by the preferred embodiment for the present invention 3, by per kilogram of body weight 2g/kg dosage, often
It 1 time, be used in conjunction 7 to 10 days；The rear observation infected cattle affected part swelling of medication 6 days or so is disappeared；Rear observation infected cattle affected part is opened within 12 days or so
Begin to heal；Follow-up after January has no recurrence.
Test medical record 3
Certain cultivation poultry raiser's reflection, has in the recent period 3 cattle lower jaw parts swelling occur.
Clinical examination and diagnosis：Infected cattle body temperature raise, in intermittent fever, conjunctiva flushing, loss of appetite, the swelling of lower jaw position,
Clear yellow viscous puss, the visible grass cuttings contamination in wound are flowed out at ulceration.
Treatment：From compositionss powder prepared by the preferred embodiment for the present invention 4, it is administered by per kilogram of body weight using gavaging
2g/kg dosage, once a day, is used in conjunction 7 to 10 days；Medication rear infected cattle affected part swelling in 6 days or so is disappeared；15 days or so rear observation diseases
Cattle affected part starts healing；Follow-up after January has no recurrence.
Claims (5)
1. one kind treats the actinomycotic Chinese medicine composition of milch cow, it is characterised in that include by weight：Aspongopuss 25-45 parts,
Herba Violae 55-75 parts, Pseudobulbus cremastrae seu pleiones 40-60 parts, Herba Elephantopi Mollis 20-40 parts, Hibisci Mutabilis 60-80 parts, Commelina paludosa 40-60 parts,
Folium sidae alnifoliae 20-40 parts, Herba Pteridis Semipinnatae 60-80 parts, white back of the body Radix sidae acutae 60-80 parts, Herba Polygalae Japonicae 20-40 part, crow hold back prunus mume (sieb.) sieb.et zucc. 15-25 parts, Tang
Ancient spy's ultramarine 25-45 part, Radix Adenophorae (Radix Glehniae) 40-60 parts, Radix Glycyrrhizae (processed with honey) 15-30 parts, Radix Platycodoniss 5-15 parts.
2. it is according to claim 1 to treat the actinomycotic Chinese medicine composition of milch cow, it is characterised in that to wrap by weight
Include：25 parts of Aspongopuss, 55 parts of Herba Violae, 40 parts of Pseudobulbus cremastrae seu pleiones, 20 parts of Herba Elephantopi Mollis, 60 parts of Hibisci Mutabilis, 40 parts of Commelina paludosa, pus
See anxious 20 parts, 60 parts of Herba Pteridis Semipinnatae, white 60 parts of Radix sidae acutae of the back of the body, 20 parts of Herba Polygalae Japonicae, crow hold back 15 parts of prunus mume (sieb.) sieb.et zucc., 25 parts of Tang Gute ultramarine, Radix Adenophorae (Radix Glehniae)
40 parts, 15 parts of Radix Glycyrrhizae (processed with honey), 5 parts of Radix Platycodoniss.
3. it is according to claim 1 to treat the actinomycotic Chinese medicine composition of milch cow, it is characterised in that to wrap by weight
Include：45 parts of Aspongopuss, 75 parts of Herba Violae, 60 parts of Pseudobulbus cremastrae seu pleiones, 40 parts of Herba Elephantopi Mollis, 80 parts of Hibisci Mutabilis, 60 parts of Commelina paludosa, pus
See anxious 40 parts, 80 parts of Herba Pteridis Semipinnatae, white 80 parts of Radix sidae acutae of the back of the body, 40 parts of Herba Polygalae Japonicae, crow hold back 25 parts of prunus mume (sieb.) sieb.et zucc., 45 parts of Tang Gute ultramarine, Radix Adenophorae (Radix Glehniae)
60 parts, 30 parts of Radix Glycyrrhizae (processed with honey), 15 parts of Radix Platycodoniss.
4. it is according to claim 1 to treat the actinomycotic Chinese medicine composition of milch cow, it is characterised in that to wrap by weight
Include：37 parts of Aspongopuss, 67 parts of Herba Violae, 50 parts of Pseudobulbus cremastrae seu pleiones, 28 parts of Herba Elephantopi Mollis, 70 parts of Hibisci Mutabilis, 50 parts of Commelina paludosa, pus
See anxious 30 parts, 67 parts of Herba Pteridis Semipinnatae, white 64 parts of Radix sidae acutae of the back of the body, 30 parts of Herba Polygalae Japonicae, crow hold back 17 parts of prunus mume (sieb.) sieb.et zucc., 38 parts of Tang Gute ultramarine, Radix Adenophorae (Radix Glehniae)
48 parts, 20 parts of Radix Glycyrrhizae (processed with honey), 9 parts of Radix Platycodoniss.
5. it is according to claim 1 to treat the actinomycotic Chinese medicine composition of milch cow, it is characterised in that to wrap by weight
Include：32 parts of Aspongopuss, 62 parts of Herba Violae, 48 parts of Pseudobulbus cremastrae seu pleiones, 24 parts of Herba Elephantopi Mollis, 66 parts of Hibisci Mutabilis, 46 parts of Commelina paludosa, pus
See anxious 26 parts, 62 parts of Herba Pteridis Semipinnatae, white 60 parts of Radix sidae acutae of the back of the body, 38 parts of Herba Polygalae Japonicae, crow hold back 20 parts of prunus mume (sieb.) sieb.et zucc., 32 parts of Tang Gute ultramarine, Radix Adenophorae (Radix Glehniae)
44 parts, 18 parts of Radix Glycyrrhizae (processed with honey), 5 parts of Radix Platycodoniss.
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