WO2015058563A1

WO2015058563A1 - Natural composite powder for improving immunity, and preparation method and application thereof

Info

Publication number: WO2015058563A1
Application number: PCT/CN2014/082495
Authority: WO
Inventors: 肖天存; 陈仁菊; 张鹏飞; 李丽
Original assignee: 广州博能生物科技有限公司
Priority date: 2013-10-21
Filing date: 2014-07-18
Publication date: 2015-04-30
Also published as: CN104543811A; CN104543811B

Abstract

A natural composite powder for improving immunity, and preparation method and application thereof; the composite powder comprises the following raw materials in parts by weight: 1-50 parts of cabbage powder, 1-100 parts of wheat flour, and 0-50 parts of other vegetable powder and/or fruit powder. The composite powder is prepared by employing superfine grinding technology.

Description

Natural composite powder for improving immunity and preparation method and application thereof

Technical field

The invention relates to the technical field of health foods, in particular to a natural composite powder for improving immunity and a preparation method and application thereof. Background technique

In modern society, due to the accelerated pace of life and the refinement of the diet structure, more and more people lack sufficient supplements of vegetables and fruits, resulting in decreased immunity and some sub-health problems such as constipation, oral ulcers, bad breath, and stomach. Discomfort, obesity, etc. The main foods such as bread, taro, and cake that modern people often eat are mainly used as supplementary foods to supplement the energy of the dietary fiber, vitamins, minerals, and folic acid.

In addition, in daily life, traditional cooking foods, especially vegetables and other foods are often eaten in large chunks, in which dietary fiber and some nutrients such as vitamin K, minerals, glucosinolates, etc., which are wrapped in the cell walls of vegetables, are difficult to be Fully absorbed. In particular, children eat fast, and the elderly are unable to fully chew and other factors because of the deterioration of dental function, making it difficult for the nutrients in vegetables to be completely absorbed.

In order to solve the problem of uneven nutrition in the modern population, there are also many technologies that combine staple foods such as flour, rice flour and vegetables to make food such as vegetable noodles, taro and bread. However, careful study of these technical solutions, it is not difficult to find that the vegetables in these technical solutions are added with fresh vegetable juice to meet the surface (as shown in the following documents: Chen, F. and Q. Chen, Manufacture of fast food containing non- Fried cucumber juice noodles and seasonings, 2011, Peop. Rep. China, and Chen, F. and Q. Chen, Manufacture of fast food containing non-fried buckwheat juice noodles and seasonings, 2011, Peop. Rep. China ) Insoluble nutrients such as most dietary fiber, vitamin K, and minerals trapped in the cell wall cannot enter the vegetable juice, which is often discarded as a residue after juicing. go with. Moreover, the extraction of nutrients in vegetable juice is difficult to quantify, and the changes in nutrients are greatly affected by the seasons. It is impossible to ensure accurate nutrition and flour configuration, which limits the stability of food types and product quality. Therefore, people often have some sub-health problems. Among them, constipation is a common clinical complex symptom, mainly refers to the reduction of the number of defecations, the reduction of feces, the dryness of feces, and the difficulty of defecation. With the refinement of people's eating habits, the reduction of exercise, and the increase in life pressure, there are more and more constipation people. Epidemiological survey data showed that the prevalence of constipation in the elderly over 65 years old in China was 8.7-19. 5 %; the prevalence rate of children aged 7-12 was 4.4%; the constipation in the community accounted for 17.6%; and women were sick The rate is more than 4 times that of men. In a pilot survey, 2,892 residents of Guangzhou City, the First Affiliated Hospital of the Third Affiliated Hospital of Zhongshan Medical University and the Third Hospital, conducted a questionnaire survey. The results showed that the prevalence of functional constipation in Guangzhou residents was 30%, and female patients were far away. Higher than male patients, and with age, the prevalence of functional constipation increases. Moreover, for advanced tumors and cancer patients, due to spleen loss of health, lack of yin and yin, constipation is very common. Constipation can be divided into two categories: organic and functional. In people with a history of constipation, functional constipation accounts for about 50%. Modern medicine treats constipation mainly by irritating excretion. The drugs used are: polyethylene glycol, lactulose, sorbitol, etc. The long-term use of these drugs is likely to cause patients' dependence on drugs and damage the body's water. Balanced with electrolytes, damage to intestinal neurotransmitters, and side effects are large.

Oral ulcers account for about 25% - 30% of oral diseases, of which recurrent oral ulcers account for about 10%-20% of the total population, and the number of female patients is higher than that of males. If both parents have recurrent oral ulcers, their children have an 80-90% chance of getting sick. Oral ulcers seriously affect people's lives and work. However, there is no specific reason for the onset of oral ulcers. The explanation from the perspective of Chinese medicine is caused by dryness and anger, emotional fluctuations or excessive mental stress, improper diet, and chronic illness. Oral ulcers are easily caused by the supply of vegetables and fruits, work stress, lack of sleep, and poor living conditions.

Bad breath refers to the odor emitted from the mouth or other air-filled cavities such as the nose, sinuses, and pharynx. It seriously affects people's social interaction and mental health. The WHO has reported bad breath as a disease. According to the survey, the prevalence of bad breath in China is 27.5%. In Western countries, it is 50%. About 10% to 65% of people worldwide suffer from bad breath. In general, due to the fire, the stomach fire is too hot, the toxins are accumulated, and the bad breath problem is more common.

Gastrointestinal disease is a disease that has a high incidence in most people, especially in the long-term Among the socially motivated people, they often suffer from gastric mucosal damage and flatulence, forming an old stomach.

These diseases, which are currently difficult to cure, can improve symptoms and even heal by improving the body's own immunity. Summary of the invention

Based on this, it is an object of the present invention to overcome the deficiencies of the prior art and to provide a natural composite powder which enhances immunity.

In order to achieve the above object, the present invention adopts the following technical solutions:

A natural composite powder that enhances immunity, including the following parts by weight:

Cabbage powder 1-50 parts

Wheat flour 1~100 parts

Other vegetables and / or fruit powder 0 ~ 50

The other vegetables and/or fruits are: spinach, Chinese cabbage, tomato, oil cabbage, oil wheat, white radish, carrot, celery, white kidney bean, strawberry, lotus root, apple, kelp, seaweed, fungus, shiitake mushroom, straw mushroom, Flammulina velutipes, puerarin, beetroot, loofah, loofah, sweet potato, bean sprouts, leeks, onions, pumpkin squash, bitter gourd, pineapple, mango, banana, hawthorn, pomegranate, mangosteen, jujube, jujube.

Brassica oleracea L. var. acephala DC. is a cruciferous plant of the genus Brassica. Cabbage is rich in nutrients, contains a lot of vitamins A, B, C, D and K, as well as a variety of minerals, especially vitamins 1 ^ vitamin D and calcium are necessary to promote child development and bone growth, to prevent bone loosening in the elderly Substance (Refer to the following documents: Cranenburg, ECM, et al., Vitamin K intake and status are low in hemodialysis patients. Kidney Int., 2012. 82 (Copyright (C) 2013 American Chemical Society (ACS). All Rights Reserved. ): p. 605-610, and Je, SH, et al., Vitamin K supplement along with vitamin D and calcium reduced serum concentration of undercarboxylated osteocalcin while increasing bone mineral density in Korean postmenopausal women over sixty-years old. J. Korean Med. Sci., 2011. 26 (Copyright (C) 2013 American Chemical Society (ACS). All Rights Reserved.): p. 1093-1098 ). The glucosinolates contained therein are the main components for increasing immunity and fighting cancer. The invention firstly superfinely pulverizes cabbage and other vegetables and/or fruit powder to obtain a nutrient-complete vegetable dry powder, and then combines with other staple foods, and then supplements the carrier part used as a staple food material in the traditional technology, and overcomes the conventional staple food. The shortcomings of few trace elements and low concentration have fundamentally solved the problem that the staple food cannot fully supplement trace elements. Moreover, the raw materials are also rich in other biologically active factors, such as glucosinolates, polyphenols, terpenoids, mercapto compounds, spices, and plant pigments, terpenoids, porphyrins, protease inhibitors, Flavonoids and saponins can enhance human immunity, anti-oxidation, anti-aging, etc., and fundamentally improve the human body.

In one embodiment, the vegetable is a vegetable having a glucosinolate content of 0.05% or more in the dry product. Glucosinolates are a class of sulfur-containing secondary metabolites found in cruciferous plants. Sulfate is itself a stable class of compounds, but it degrades under the catalysis of a mustard enzyme or a bacterial enzyme in the gastrointestinal tract and produces a variety of degradation products. There are many studies (eg: Srinibas Das, Amrish Kumar Tyagi and Harjit Kaur (2000). "Cancer modulation by glucosinolates: A review". Current Science 79(12): 1665; Another example: Jump upHayes, JD, Kelleher, MO; Eggleston, IM (2008). "The cancer chemopreventive actions of phytochemicals derived from glucosinolates. ".European journal of nutrition. 47 Suppl 2: 73-88) shows that glucosinolates have the effect of improving immunity and anti-cancer, especially Protects intestinal immune cells and protects against oxidation. Therefore, when a vegetable rich in glucosinolates is included, the immune-complexing natural complex powder has the function of regulating the digestive system.

In one embodiment, the immunocompetent natural composite powder further comprises at least one of the following parts by weight:

Nut powder 1-50 parts

Probiotic powder 1-5 parts

Special food powder 1-50 parts

Carrier powder 1-50 parts

The nuts are: at least one of peanuts, walnuts, pistachios, macadamia nuts, almonds, silver almonds, pine nuts, cashews, sunflower seeds, chestnuts, figs, pumpkin seeds, and hazelnuts; The probiotics are: Bifidobacterium adolescentis, Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus crispa, Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus fermentum, Lactobacillus gasseri, Lactobacillus helveticus, Lactobacillus johnsonii, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus salivarius, Streptococcus thermophilus, Yeast At least one type;

The special ingredients are: West Lake Longjing, Taihu Biluochun, Huangshan Maofeng, Lu'an Melon, Junshan Yinzhen, Xinyang Maojian, Osmanthus fragrans, rose, oolong tea, Pu'er tea, camphor bud, barley seedling, rape pollen, tea pollen, lotus At least one of leaves, loofah seedlings, barley seedlings, magnolia, lotus, rose, rose, sassafras, sable, pear, arborvitae, honeysuckle, sage, sassafras, aloe;

The carrier powder is at least one of rice flour, barley flour, millet flour, soybean powder, sweet potato powder, konjac flour, earth bean powder, yam powder, sorghum powder, corn flour, and taro powder.

By selectively adding nut powder, probiotic powder, special food powder and carrier powder, it is possible to mix nutrients more flexibly and to obtain a composite powder with different specificity or nutrient composition.

In one embodiment, the immune-enhancing natural composite powder comprises the following parts by weight of raw cabbage powder 2-8 parts

Spinach Powder 0.5-1.5 parts

Apple powder 0.5-1.5 parts

Beetroot powder 1-3 parts

Walnut powder 5-15 parts

Wheat flour 40-85 servings

Potato flour 5-15 servings

Barley seedling powder 0.5-1.5 parts.

The composite powder having the above components has a particularly good effect in preventing and treating oral ulcers. In general, the treatment of oral ulcers is usually through repairing the ulcer surface, promoting the healing of the ulcer surface, and supplementing nutrients to enhance physical fitness. The conditioning mechanism of the composite powder for oral ulcers mainly has the following points: 1. The composite powder is rich in dietary fiber, can promote the cleaning of toxins in the body, and reduce the evil in the body; The compound powder is rich in B vitamins and anti-ulcer factors such as vitamin Kl and vitamin U, which can promote the repair and healing of the ulcer surface. 3. The composite powder contains special biological active factors, such as rich glucosinolates in cabbage. Chlorophyll can have good effects against oxidation, anti-fatigue, anti-cancer, etc. Long-term consumption can improve the overall immunity of the human body. It works in many ways to achieve the effect of preventing and treating oral ulcers.

In one embodiment, the immune-enhancing natural composite powder comprises the following parts by weight of the raw material:

Cabbage powder 5-15 parts

Kelp powder 1.5-3.5 parts

Pueraria powder 1.5-3.5 parts

Celery powder 2-8 parts

Wheat flour 60-100 parts.

The composite powder having the above components has a particularly good effect in preventing and treating constipation. The compound powder is based on the dialectical theory of Chinese medicine, that is, in diet therapy, according to the characteristics of constipation, the selection of the ingredients from the soft liver and spleen and warm kidney, combined with the mechanism of the nutrition of modern nutrition and the digestion and absorption in the human body. , using dietary fiber-rich products, can promote intestinal peristalsis, regulate intestinal flora; at the same time with a certain water absorption coefficient, with a function of the intestinal function (ie, raw materials rich in dietary fiber), combined with food nutrition The theory of learning is combined with a product rich in vitamins and minerals. On the one hand, it regulates constipation from the mechanism, on the other hand, it enhances immunity by balancing nutrient requirements, and promotes the movement of large intestine smooth muscle to replenish constipation. the goal of.

Cabbage powder 5-15 parts

Beetroot powder 2-8 parts

Spinach powder 1-3 servings

Potato flour 15-25 servings

Wheat flour 40-60 servings 5-15 parts of corn flour

Barley seedling powder 2-4 parts.

The composite powder having the above components has a particularly good effect in conditioning the stomach. The dietary fiber in the composite powder helps to slow down the absorption of alcohol, harmful pesticide residues, food additives, etc. The adsorption function and defecation function of dietary fiber can contain some substances harmful to the human body and promote these harmful substances quickly. Excreted from the body, thereby reducing the impact of such substances on the human body; the complex B-rich vitamins and anti-ulcer factors vitamin K1, vitamin U helps the repair of the gastrointestinal ulcer surface; and contains special active substances For example, betaine hydrochloride can supplement the deficiency of human digestive juice, promote digestion, enhance organ function, and thus regulate the stomach.

Cabbage powder 5-15 parts

Kelp powder 1-3 parts

Banana powder 1-3 servings

Bitter melon powder 0.5-1.5 parts

Yeast powder 0.5-1.5 parts

Wheat flour 60-100 parts.

The composite powder having the above components has a particularly good effect in preventing and treating bad breath. The conditioning mechanism of the composite powder for bad breath is: rich in dietary fiber, can promote detoxification, clean the stomach and reduce the fire phenomenon; at the same time, the rich dietary fiber can balance the intestinal flora, promote the growth of probiotics, and balance the intestinal tract. The flora also helps to remove toxic substances, and can also produce beneficial small molecular substances that are beneficial to human health. The dietary fiber in the composite powder also has the characteristics of small particle size and high solubility, and is more effective than dietary fiber in traditional food.

Cabbage powder 2-6 parts Kelp powder 0.5-2 parts

Wheat flour 80-100 parts.

The composite powder having the above components has a particularly good effect in comprehensively supplementing nutrients and improving immunity.

The invention also provides a method for preparing the above-mentioned natural composite powder for improving immunity, comprising the following steps:

The above various raw materials are separately selected, dried, pulverized by ultrafine pulverization technology, and fine powders each having a particle diameter of 0.15 mm or less are prepared, and then mixed and mixed according to the weight ratio, thereby obtaining natural immunity for human immunity. Composite powder.

Ultra-fine pulverization technology includes hot pulverization, low-temperature air pulverization, mainly to crush and break the hard-to-crush and hard-to-absorb components in vegetables and fruits to ensure that the nutrients are fully absorbed and released, and finally made into granules. Fine powder with a diameter of less than or equal to 0.15mm, with good solubility, adsorption, dispersibility and nutritional activity, easy to digest and absorb, can be used as diet food, food for diabetes, middle-aged food, infant food, health food, fortification Food and special nutritious foods, etc. When the pulverization reaches 100 mesh or more (that is, the particle size reaches 0.15 mm or less), the cell wall of most plants will be destroyed, which will promote the release of the active ingredients in the plant for the body to absorb and utilize, increasing the nutritional efficiency of the food and improving The nutritional value of the product.

The present invention also provides the use of the above-mentioned immune-complexing natural complex powder for the preparation of a product for preventing and treating constipation, or oral ulcer, or bad breath, or gastrointestinal diseases. The natural compound powder for improving immunity can be made into bread, taro, Hanamaki, noodles, rice noodles, vermicelli, biscuits, candy, cakes, pancakes, vegetable paper, egg rolls, flatbread, buns, mash, dumplings, fried dough sticks, noodles疙瘩, 馄饨, cool skin, gluten, tofu, yuba, soy milk, porridge, instant noodles and other products, widely used.

Compared with the prior art, the present invention has the following beneficial effects:

The natural composite powder for improving immunity of the invention adds cabbage powder and other vegetable and fruit powders to the carrier powder, and the obtained composite powder not only can supplement the energy required by the human body, but also can supplement the dietary fiber required by the human body. , vitamins, minerals and folic acid and other nutrients. Moreover, these nutrients are present in the food as fine powder, and these ingredients are more easily absorbed than ordinary vegetables. It also has the effect of promoting each other and synergistically, ensuring the nutritional balance of the body, and has a particularly good effect in preventing and treating constipation, or oral ulcers, or bad breath, or gastrointestinal diseases, and promoting the development and healthy growth of children.

Moreover, the raw materials for the composite powder are all edible fruits and vegetables such as daily consumption, and the adverse effects and toxicity of the traditional Chinese medicine on the human body are reduced.

In the preparation method, we first pre-treat, disinfect and remove the harvested vegetables. After drying and fine treatment, a dry vegetable powder is obtained. The vegetable dry powder is compounded according to different groups of people, and then mixed with the flour to be processed to produce foods suitable for different groups of people. This ultrafine comminution ensures that the whole nutrients of the vegetables are easily absorbed. The obtained composite dried fruit and vegetable powder is mixed with flour to ensure storage stability and product quality.

DRAWINGS

1 is a schematic view showing the content of nutrient components of a composite vegetable and fruit taro in a specific embodiment. detailed description

The invention is illustrated in detail below by way of specific examples without any limitation of the invention. The raw materials in the present invention are comprehensively considered from the perspective of nutritional diet, and the main nutrient elements of the human body are added according to the recommended proportion and energy consumption ratio of the scientific diet, according to the NRV (nutrient reference value) 曰 recommended intake standard (see table 1), rationally allocate and calculate the mix of raw materials, so that the overall product reaches or is close to the proportion of each element in the table below.

Table 1. NRV recommended intake standard

NRV / day NRV / day

Vitamins (continued)

•6匕 County

Fi 8400 kJ pantothenic acid 5 mg protein 60 g biotin

Fat <60 g Choline 450 mg Saturated Fatty Acid <20 g Cholesterol <300 mg minerals

Total Carbohydrate 300 g Calcium 800 mg Dietary Fiber 25 g Brick 700 mg

Vitamin K 2000 mg Vitamin A 80 (^gRE 2000mg Vitamin D Magnesium 300 mg Vitamin E 14mga-TE Iron 15 mg Vitamin K 80μ8 Word 15 mg Vitamin B1 1.4 mg Iodine 15 (^g Vitamin B2 1.4 mg Shixi 50μ8 Vitamin B6 1.4 mg Copper 1.5 mg Vitamin B12 Fluoride 1mg Vitamin C 100 mg Chromium 50μ8

Niacin 14 mg manganese 3 mg folic acid 40 (^g molybdenum

Wherein: gRE represents a substance having vitamin Α activity including retinol and β-carotene, which corresponds to the amount of retinol; a-TE represents an equivalent, and corresponds to the content of vitamin E.

Content), as shown in Figure 1.

Example 1

The natural complex powder for improving immunity has a particularly good effect in preventing and treating oral ulcers, and is composed of the raw materials shown in Table 2 below:

Table 2. Three kinds of natural composite powder formula for improving immunity, composite powder A, composite powder B, composite powder C

Raw materials, parts by weight, parts by weight, parts by weight

Cabbage powder 5 2 8

Spinach Powder 1 0.5 1.5

Apple Powder 1 0.5 1.5 Beetroot powder 2 1 3

Walnut powder 10 5 15

Wheat flour 60 40 85

Potato flour 10 5 15

Barley seedling powder 1 0.5 1.5

The preparation method of the above composite powder is:

1. Select the above-mentioned wheat, potatoes, walnuts, kale, beetroot, spinach, barley seedlings, apples and other raw materials.

2. Pretreatment and powdering of raw materials All raw materials are decontaminated, decontaminated, sterilized, dehydrated, etc. according to their characteristics, and the edible parts are prepared into powdery raw materials of 100-1000 mesh.

3. Add all vegetables, fruits, nuts, carrier dry powder and other raw materials according to the formula of Table 2 and weigh them by electronic means.

4. Dispensing The various raw materials weighed are mixed into a uniform powder by a quick mixer.

5, sterilization

The mixed raw material powder in step 4 is sterilized by gamma ray to ensure that the bacterial content is in compliance with GMP standards.

6. Inspection According to scientific sampling standards, samples are taken for component analysis and safety testing.

7, packaging and storage

The composite powder that has passed the test in step 6 is packaged in a sealed hygienic package and stored in an environment below 15 °C in accordance with food storage standards.

Effect test:

1. Experimental data: 403 patients aged 20-60 years old who were treated and hospitalized in Luoyang Petrochemical Hospital from February 2013 to May 2013 were selected. The composite powder A, composite powder B and composite powder C prepared above were prepared. And the composite powder D, the composite powder E and the composite powder F prepared according to the following Table 3 components, and the common wheat flour, respectively, are prepared into pancakes, and the therapeutic effect of the pancake product on oral ulcers is taken as an investigation factor. Clinical trials.

Table 3. Three reference composite powder formulas

2. Sample selection criteria: The history of oral ulcer recurrence is more than 1 year, periodic recurrence, more than 2 times per month, and the onset period is more than 5 days; the ulcer is round or oval, scattered in the oral mucosa. Superficial ulcers, local burning pain; no other oral mucosa and systemic diseases; no antibiotics and oral ulcers have been taken in the near future; no immunosuppressive agents and immunosuppression have been used within 3 months The ulcer occurred less than 48 hours; and no treatment was performed after the onset of the disease.

3. Evaluation criteria for clinical trial results:

Effective: This product takes 7 days as a course of treatment, which is effective when the patient's corresponding symptoms are significantly improved within one course of treatment. For example, the onset of oral ulcers is effective within 24 hours, and healed within 7 days; the frequency of recurrent oral ulcers decreases within one month. Invalid: The patient with the corresponding symptom was not resolved.

4. Results and analysis

The experimental results are shown in Table 4 below.

Table 4. Therapeutic effect on oral ulcers Number of participants Effective number of invalids Number of people effective Compound powder A prepared pancakes 64 55 9 85.9% Composite powder B prepared pancakes 59 48 11 81.36% Composite powder C prepared pancakes 61 49 12 80.33% Composite powder D prepared pancakes 56 38 18 67.86%

Composite powder E prepared pancakes 58 32 26 55.17%

Pancake prepared from composite powder F 55 31 24 56.36%

Pancake prepared from wheat flour 50 10 40 20.00%

It can be seen from the above results that the addition of vegetable and fruit powder has a certain therapeutic effect on oral ulcers, in particular, the composite powder AC prepared in this embodiment has a special treatment for oral ulcers compared with the reference composite powder DF. Good results, the efficiency is more than 80.33%. It can also be seen that in the treatment of oral ulcers, the type and ratio of raw materials are very important characteristics, and the raw materials can cooperate with each other to achieve better results.

Example 2 A natural composite powder for improving immunity has a particularly good effect in preventing and treating constipation, and is composed of the raw materials shown in Table 5 below:

Table 5. Three natural complex powder formulas for improving immunity

The above composite powder was prepared in accordance with the method of Example 1.

Effect test:

1. Experimental data: 419 patients who were treated and hospitalized in Luoyang Petrochemical Hospital from February 2013 to May 2013, aged 20-60 years old, were prepared as the composite powder G, composite powder H, and composite powder I. And the composite powder J, the composite powder K and the composite powder L prepared according to the following 6 components, and the common wheat flour, respectively, are prepared into steamed bread, and the therapeutic effect of the constipation of the steamed bread product is taken as an investigation factor for clinical experiments.

Table 6. Three reference composite powder formula composite powder J composite powder K composite powder L Raw material parts by weight parts by weight

Cabbage powder 2 5 15

Kelp powder 5 1.5 3.5

Pueraria powder 6 - 3.5

Celery Powder 1 2 - Wheat Flour 140 60 100

Macaroni - - 4

2. Sample selection criteria:

Constipation: At least 6 months of constipation history, constipation patients have no organic disease, the number of spontaneous spontaneous bowel movements per week <3 times and at least one of the following symptoms: (1) Defecation is hard or very hard (2) There is a feeling of incomplete emptying after defecation; (3) There is laborious defecation.

3. Evaluation criteria for clinical trial results:

Effective: This product takes 7 days as a course of treatment, which is effective when the patient's corresponding symptoms are significantly improved within one course of treatment. For example, the number of bowel movements in patients with constipation increases, the time of defecation is shortened, and the hardness of bowel movements is reduced.

Invalid: The patient with the corresponding symptom was not resolved.

4. Results and analysis

The experimental results are shown in Table 7 below.

Table 7. Therapeutic effect on constipation

It can be seen from the above results that the addition of vegetable and fruit powder has a certain therapeutic effect on constipation, in particular, the composite powder GI prepared in this embodiment is particularly good in treating constipation compared with the reference composite powder JL. The effect is more than 83.61%. It can also be seen that in the treatment of constipation, the type and ratio of raw materials are very important characteristics, and the raw materials can cooperate with each other to achieve more synergy. Good results.

Example 3 A natural composite powder for improving immunity has a particularly good effect on stomach, stomach, stomach and flatulence, and is composed of the materials shown in Table 8 below:

Table 8. Three natural compound powder formulas for improving immunity

Effect test:

1. Experimental data: 182 patients aged 20-60 years old who were treated and hospitalized in Luoyang Petrochemical Hospital from February 2013 to May 2013 were selected. The composite powder M, compound powder N, and compound powder prepared above were prepared. And the composite powder P, the composite powder Q and the composite powder R prepared according to the following 9 components, and the common wheat flour, respectively, are prepared into noodles, and the effect of regulating the stomach of the noodle product as an investigation factor is carried out for clinical experiments. Table 9. Three Reference Composite Powder Formula Composite Powder P Composite Powder Q Composite Powder R

Raw materials, parts by weight, parts by weight, parts by weight

Cabbage powder 2 5 15

Beetroot Powder 1 2 - Spinach Powder 5 1 3

Potato flour 50 15 25

Wheat flour 80 40 60

Corn flour 2 - 15

Barley seedling powder 0.5 2 4 Jj vegetable powder I - ί - I 5

2. Sample selection criteria:

Stomach, stomach, stomach, flatulence: There are more than one year of stomach disease, and one of the following symptoms (1) often snoring, nausea, and sour water; (2) easy to flatulence, such as eating uncooked food, fresh fruit, or easy When producing gas food; (3) It may cause stomach pain to irritating foods such as drinking alcohol and eating chili, and even vomiting in severe cases.

3. Evaluation criteria for clinical trial results:

Effective: This product takes 7 days as a course of treatment, which is effective when the patient's corresponding symptoms are significantly improved within one course of treatment. Patients with stomach, stomach, stomach and flatulence have symptoms that are alleviated when they are affected by irritating factors.

Invalid: The patient with the corresponding symptom was not resolved.

4. Results and analysis

The experimental results are shown in Table 10 below.

Table 10. Therapeutic effect of stomach flatulence and stomach flatulence

It can be seen from the above results that after the addition of vegetable and fruit powder, there is a certain therapeutic effect on stomach acid and stomach bloating, especially the composite powder M-0 prepared in this embodiment is compared with the reference composite powder PR, in the stomach stomach pain. It has a particularly good effect on the improvement of flatulence, and the effective rate is above 84.00%. When regulating the stomach, stomach, stomach and flatulence of the gastrointestinal tract, the type and proportion of the raw materials are very important characteristics. The raw materials can cooperate with each other to achieve better results. A natural composite powder for improving immunity, which has a particularly good effect in preventing and treating bad breath, and is composed of the raw materials shown in Table 11 below:

Table 11. Three natural complex powder formulas for improving immunity

The preparation method of the above composite powder is referred to in Example 1.

Effect test:

1. Experimental data: 127 patients aged 20-60 years old who were treated and hospitalized in Luoyang Petrochemical Hospital from February 2013 to May 2013 were selected. The composite powder S, composite powder T and composite powder U prepared above were selected. And the composite powder V, the composite powder W and the composite powder X prepared according to the following 12 components, and the common wheat flour, respectively, are prepared into bread, and the therapeutic effect of the bad breath of the bread product is taken as an investigation factor, and a clinical experiment is conducted.

Table 12. Composite powder formula for three comparative tests

2. Sample selection criteria:

Bad breath: A history of bad breath for at least 6 months, with obvious bad breath after getting up or communicating with people; no other serious organ disease.

3. Evaluation criteria for clinical trial results: Effective: This product takes 7 days as a course of treatment. It is effective when the patient's corresponding symptoms are significantly improved within one course of treatment. For example, patients with bad breath use a gas tone meter to measure the H ₂ S content in the breath. It is effective to reduce or completely improve the breath after 7 days.

Invalid: The patient with the corresponding symptom was not resolved.

4. Results and analysis

The experimental results are shown in Table 13 below.

Table 13. Treatment effect on bad breath

It can be seen from the above results that the addition of vegetable and fruit powder has a certain therapeutic effect on bad breath. In particular, the composite powder SU prepared in this embodiment has a special improvement on bad breath compared with the reference composite powder VX. Good results, effective rate of 81.82% or more. In the treatment of bad breath, the type and proportion of raw materials are very important characteristics, and the raw materials can cooperate with each other to achieve better results. Example 5

A natural composite powder for improving immunity, consisting of the following raw materials by weight:

Cabbage powder 6 parts

Spinach powder 2 parts

Kelp powder 2 parts

90 parts of wheat flour.

According to the operation steps of the first embodiment, each raw material powder is prepared, and mixed and hooked, and packaged.

The nutritional content of each 100 g of the composite powder in this example is shown in Table 14 below:

Table 14. Table of nutrient composition of natural compound powder for improving immunity in this example

As can be seen from the above Table 14, the nutritional powder prepared in this embodiment is comprehensive and diverse, and can ensure the body's nutritional balance.

However, it is not to be construed as limiting the scope of the invention. It should be noted that a number of variations and modifications may be made by those skilled in the art without departing from the spirit and scope of the invention. Therefore, the scope of the invention should be determined by the appended claims.

Claims

claims

1. A natural compound powder for improving immunity, which is characterized in that it includes the following parts by weight of raw materials: Cabbage powder 1-50 parts

Wheat flour 1~100 parts

Other vegetable and/or fruit powder 0~50 servings

The other vegetables and/or fruits are: spinach, Chinese cabbage, tomato, cabbage, lettuce, white radish, carrot, celery, white kidney beans, strawberry, lotus root, apple, kelp, seaweed, fungus, shiitake mushroom, straw mushroom, At least one of enoki mushrooms, kudzu root, beetroot, luffa, luffa seedlings, sweet potato seedlings, bean sprouts, leeks, green onions, pumpkin seedlings, bitter melon, pineapple, mango, banana, hawthorn, pomegranate, mangosteen, jujube, and wild jujube.

2. The natural compound powder for improving immunity according to claim 1, characterized in that the vegetables are vegetables with a glucosinolate content of greater than or equal to 0.05% in dry products.

3. The natural compound powder for improving immunity according to claim 1, further comprising at least one of the following raw materials in parts by weight:

Nut powder 1-50 parts

Probiotic powder 1-5 servings

Special ingredient powder 1-50 servings

Carrier powder 1-50 parts

The nuts are: at least one of peanuts, walnuts, pistachios, macadamia nuts, almonds, ginkgo almonds, pine nuts, cashew nuts, sunflower seeds, chestnuts, figs, pumpkin seeds, and hazelnuts;

The probiotics are: Bifidobacterium adolescentis, Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus crispatus, Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus fermentum, Lactobacillus gasseri, Lactobacillus helveticus, Lactobacillus johnsonii, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus salivarius, Streptococcus thermophilus, yeast at least one of;

The special ingredients are: West Lake Longjing, Taihu Biluochun, Huangshan Maofeng, Lu'an Guapian, Junshan Silver Needle, Xinyang Maojian, osmanthus, rose, oolong tea, Pu'er tea, toona buds, barley seedlings, rapeseed pollen, At least one of camellia pollen, lotus leaves, luffa seedlings, barley seedlings, magnolia, lotus, rose, rose, dendrobium, bigster, pear, Platycladus orientalis, honeysuckle, purpurea, sophora japonica, and aloe vera;

The carrier powder is: at least one of rice flour, barley flour, millet flour, soybean flour, sweet potato flour, konjac flour, potato flour, yam flour, sorghum flour, corn flour, and taro flour.

4. The natural compound powder for improving immunity according to claim 1, characterized in that it includes the following raw materials in parts by weight:

Cabbage powder 2-8 portions

Spinach powder 0.5-1.5 parts

Apple powder 0.5-1.5 parts

Beetroot powder 1-3 servings

Walnut powder 5-15 parts

Wheat flour 40-85 parts

Potato flour 5-15 servings

Barley grass powder 0.5-1.5 parts.

5. The natural compound powder for improving immunity according to claim 1, characterized in that it includes the following raw materials in parts by weight:

Cabbage powder 5-15 servings

Kelp powder 1.5-3.5 parts

Pueraria powder 1.5-3.5 parts

Celery powder 2-8 servings

Wheat flour 60-100 parts.

6. The natural compound powder for improving immunity according to claim 1, characterized in that it includes the following raw materials in parts by weight:

Cabbage powder 5-15 servings

Beetroot powder 2-8 servings

Spinach powder 1-3 servings

Potato flour 15-25 servings 40-60 servings of wheat flour

Corn flour 5-15 portions

Barley grass powder 2-4 parts.

7. The natural compound powder for improving immunity according to claim 1, characterized in that it includes the following raw materials in parts by weight:

Cabbage powder 5-15 servings

1-3 portions of kelp powder

Banana powder 1-3 parts

Bitter melon powder 0.5-1.5 parts

Yeast powder 0.5-1.5 parts

Wheat flour 60-100 parts.

8. The natural compound powder for improving immunity according to claim 1, characterized in that it includes the following raw materials in parts by weight:

Cabbage powder 2-6 servings

Spinach powder 0.5-2 parts

Kelp powder 0.5-2 parts

Wheat flour 80-100 parts.

9. A method for preparing natural compound powder for improving immunity according to any one of claims 1 to 8, characterized by comprising the following steps:

Various raw materials described in claims 1 to 8 are respectively selected, dried, and pulverized using ultrafine pulverization technology to prepare fine powder with a particle size of less than or equal to 0.15 mm, and then batched according to the weight ratio and mixed, that is, A natural compound powder that improves immunity.

10. Application of the natural compound powder for improving immunity according to any one of claims 1 to 8 in the preparation of products for preventing and treating constipation, oral ulcers, halitosis, or gastrointestinal diseases.