CN104146266A - Fully nutrient formula food for recuperating chloasma - Google Patents

Fully nutrient formula food for recuperating chloasma Download PDF

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CN104146266A
CN104146266A CN201410405420.8A CN201410405420A CN104146266A CN 104146266 A CN104146266 A CN 104146266A CN 201410405420 A CN201410405420 A CN 201410405420A CN 104146266 A CN104146266 A CN 104146266A
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chloasma
vitamin
food
root
medicine
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胡安然
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Jing Shanmei Biotech Inc
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A23L33/175—Amino acids
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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Abstract

The invention provides fully nutrient formula food eaten by patients with chloasma, and particularly relates to fully nutrient formula food or non-fully nutrient formula food eaten by the patients with the chloasma. A formula is developed according to the requirements of "General Rule of Special Medical Use Formula Food", by combining the constitutive characters of the patients with the chloasma, by synthesizing the research findings of American Harvard University on advanced physiology, medicine, nutriology, clinical application and the like, and according to a quintessence theory (the main principle is that three organs of liver, spleen and kidney are simultaneously recuperated) of traditional Chinese medical science, i.e. "eliminating for supplementing" and "balancing and recuperating". The product is prepared by mixing main raw materials of various medicinal and edible traditional Chinese medicine extract essence, various probiotics and short chain polypeptides and auxiliary materials of prebiotics, carbohydrate, amino acids, various vitamins and minerals, can be used as a single nutrition source to satisfy the nutrient requirements of the chloasma patients, and has the efficacies of delaying senescence, promoting blood circulation for removing blood stasis, calming the liver for improving eyesight, regulating the menstrual function for relieving pain, cooling blood for relieving pain, clearing away heart fire for relieving restlessness and strengthening immunity.

Description

The full nutrient formulation food of conditioning chloasma
Technical field
The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " medicine among integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds to take full nutrient formulation food, specific full nutrient formulation food or the non-full nutrient formulation food of the conditioning chloasma that small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter make as auxiliary material.
Background technology
Chloasma is commonly called as " butterfly macules ", " chloasma hepaticum " or " cyasma ", mainly occur in face, with cheekbone portion, cheek, nose, forehead, chin portion is main, for the brown of obscure boundary Chu or the patch of black, mostly be symmetry, irregular menstruation, gestation, take contraceptive and chronic renal patient may occur chloasma, concrete reason is as follows: 1, endocrinopathy, endocrinopathy is the main cause that causes chloasma, mainly that body microcirculation is obstructed, metabolism slows down slowly, melanin cannot excrete in time, in skin, pile up, finally cause occurring chloasma, 2, do not have enough sleep, contemporary society's pressure is large, overtime work is very common, stayed up late into generalized situations, the number of insomnia is more and more, long-time shape sleep condition can not get improving, cause skin variation, sleep is the toxin expelling time mostly, in the time of sleep, body is at toxin expelling, if because do not have enough sleep, or often stay up late, what the toxin in health just can not get discongests, melanin deposition can increase more and more, there will be on the face chloasma, 3, ultraviolet irradiation, contact too many ultraviolet ray, meeting causing serious injury skin, make to occur on the face patch, the melanin excretory system secretion melanin that can stimulate in body is irradiated in ultraviolet ray, and can not excrete in time, in skin, deposit, 4, age growth, due to age growth, skin quality is aging, skin blood has some setbacks, anisochromasia weighing apparatus, sludging and pigment stagnate and cause occurring pigment deposition, " integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science, the traditional Chinese medical science always emphasize " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet, allow people dispel slight illness in the process of enjoying cuisines, avoided having an injection, taking medicine, even the hardship of operation.
For food of special nutrients, in developed countries such as the U.S., European Union, there are corresponding regulation and Application and Development; And wholefood is clearly stipulated in China GB29922-2013 < < special medicine purposes formula food general rule > > food security national standard: the full nutrient formulation food of 2.1.1: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutrient formulation food: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition.
Some people's chloasma is caused by constipation, and being shortage due to profitable strain essential in enteron aisle, constipation cause enterocinesia slowly caused, traditional Chinese medical science traditional medicine is thought: " spleen (being digestive system) is the foundation of acquired constitution ", stomach health is healthy basis, 99% of human nutrition need to lean on intestinal absorption, and in intestines, disease is also the source of ten thousand diseases; But along with the age is larger, profitable strain in enteron aisle (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% period infant, during to the middle age, be down to and only account for 5% in 10%, 65 years old later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies show that, normal flora has many irreplaceable effects in human body digestion, immunity and the aspect such as disease-resistant; The generation development of change and various diseases, particularly intestines problem that gut flora forms is closely related, and finds from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is a kind of control method of intervening safely and effectively.
Though directly probiotic oral has certain effect, but because probio one cannot field planting in enteron aisle, and stop, occupy-place are seldom, easily run off, and withdraw rear harmful bacteria and easily recur, and associated patient needs long-term taking, and treatment cycle is long, often uses rear recurrence rate very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by studying the key technology of probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts to seek to improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can be played field planting effect, the enteron aisle adhesive capacity of the reduction of enteron aisle pH environment and raising probiotic cell etc., based on above-mentioned key element, suitable food materials screen from tens of kinds " medicines among integration of drinking and medicinal herbs " in this seminar, found first interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and jerusalem artichoke and stachyose, yeast, after Glu etc., external source probio is had to very strong field planting effect, for the prescription of probio in enteral microecological formulation selects to provide experimental basis.
Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter form compound prescription, utilize in addition the product that probio is primary raw material, but also do not find the constitutive character in conjunction with patient with chloasma, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials is the full nutrient formulation food that auxiliary material is made, specific full nutrient formulation food or similar products.
goal of the invention
The object of the invention is inheriting on the theoretical treatment method of traditional Chinese medical science marrow, the initiative extract by multiple raising body immunity probio and " medicine among integration of drinking and medicinal herbs " compound combines, interpolation is with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, not only can supplement chloasma crowd institute essential nutrients, improve body nutrition condition, can also and utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutrient formulation food that the acceptable applicable patient with chloasma of people is edible, specific full nutrient formulation food or non-full nutrient formulation food.
summary of the invention:
This R&D team is according to the requirement of < < special medicine purposes formula food general rule > >, in conjunction with the constitutive character of patient with chloasma, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears is mended ", theoretical (the liver of marrow of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, the dirty same main principle that is adjusted to of kidney three), adopt the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets patient with chloasma, delays senility in addition, promoting blood circulation, flat liver improving eyesight, menstruction regulating and pain relieving, cool blood disappears bitterly, the full nutrient formulation food of the effect of relieving restlessness and the enhancing immunity of clearing away heart-fire, specific full nutrient formulation food or non-full nutrient formulation food (compound prescription being combined into).
1, the main component of the present invention's formula is:
Chinese medical extract is that the liver,spleen,kidney from theory of traditional Chinese medical science three is dirty with being adjusted to main principle according to chloasma crowd's constitutive character, utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and choose following several large class medicine and carry out compatibility; Wherein: isoflavones is a kind of vegetalitas female hormone, natural hormone, can delaying female aging, improve menopause symptom; Grape seed extract superpower anti-oxidant, remove free radical, there is the superpower effect that delays senility and strengthen immunity; Safflower is warm in nature, and taste is pungent, activating blood to promote menstruation, blood stasis removing analgesic, for through closing, dysmenorrhoea, lochia, abdominal mass lump in the abdomen, traumatic injury; Root of bidentate achyranthes tonifying liver and kidney and strengthening bones and muscles, activating blood to promote menstruation, ignite that (blood) is descending, inducing diuresis for treating strangurtia, cure mainly flaccidity and weakness of the lower limbs, postpartum abdominal pain due to blood stasis, abdominal mass, placenta retension, traumatic injury, swollen sore, the abscess of throat of disliking of carbuncle; Motherwort nature and flavor are arduous cool, have the effect of invigorate blood circulation, the dispel stasis of blood, menstruation regulating, the water that disappears; Red sage root promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, cool blood disappear carbuncle, relieving restlessness clears away heart-fire; Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, relax bowel, for sallow, the dizzy palpitaition of the deficiency of blood, asthenia cold abdominalgia, the dry constipation of intestines, ulcer sores; Matrimony vine has the blood sugar of reduction, lipotropy, and energy antiatherosclerosis; Mulberries contain rutin, anthocyanidin, RV, have good anti-cancer, anti-ageing, antiulcer, antivirus action; Chrysanthemum is sweet, be slightly cold, and has loose wind-heat, flat liver improving eyesight, disappears and cough the effect of pain relieving, is used for the treatment of that headache is dizzy, red eye, swell pain, anemopyretic cold; Cassia seed has clearing away the liver-fire, wines used as antirheumatic, tonifying kidney and improving eyesight, can treat the problems such as coronary heart disease, high blood and eye-blurred; Poria cocos has the immunity of enhancing, antitumor and calm, hypoglycemic effect, can also prevent hepatonecrosis; The root of kudzu vine can improve the power of regeneration of stem cell, strengthens the deciphering function of liver, for prevention blackspot, whelk, chloasma hepaticum, has good effect;
Medicinal and edible Chinese medicine extract of the present invention refers to the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, isoflavones, grape seed extract, safflower, the root of bidentate achyranthes, motherwort, the red sage root, Radix Angelicae Sinensis, lucidum spore powder (broken wall), matrimony vine, peach kernel, mulberries, chrysanthemum, cassia seed, Poria cocos, the root of kudzu vine, mulberry leaf, rhizoma zingiberis, the root of Dahurain angelica, mountain Cape jasmine, aloe, hawthorn, pawpaw, lotus leaf, sea-buckthorn, rose wherein 3 kinds is above or all, adopt biological enzymolysis or prehydrolysis SBE to extract and microencapsulation, mixture after spray-dried and cryodesiccated extract.
2, multiple probio: make probio arrive enteron aisle by most of strong acid environment by stomach, to promote the propagation of probio, regulate microecological balance in intestines, promotion is to micro-absorption, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body field planting drag or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, can obviously reduce the level of intestinal endotoxemia the generation of preventing liver injury; It is also the important measures of adjusting intestinal microecology that selective enteron aisle decontamination is dyed, and has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by suppressing urease-producing in enteron aisle and producing the growth of ammonium bacteria, builds up resistance;
Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, Bifidobacterium wherein: refer to that bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum are wherein a kind of, several or all mix; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus be a kind of, several or all mixing wherein.
3, small peptide: be oligopeptide, refer to the small molecule protein that utilizes bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need through digestion and directly absorb, bioavailability is high, in absorption and utilization, be better than free amino acid and complete protein, can be applicable in Protein intake food, especially for the low crowd of abilities of digestive and absorption, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function that improves small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,
Small peptide of the present invention refers to wherein a kind of, several or all mixing of marine collagen peptide, wheat oligopeptide, maize oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.
4, prebiotics: to urge the field planting of probio enteron aisle, enteron aisle convergence, to reduce enteron aisle pH environment, by most enteron aisle spoilage organisms, do not utilized yet, but can promote beneficial bacteria---the growth and breeding of lactobacillus, Bifidobacterium in human body, thereby can suppress spoilage organisms growth, contribute to improve and maintain enteron aisle normal function; Long-term edible can delay senility, defaecation, raising immunity, alleviate burden of liver, improve the absorptivity of nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, pH value in colon is reduced, the growth of inhibition harmful intestinal tract bacterium; Make Water-Electrolyte in small intestine be trapped in enteric cavity, produce the high effect of oozing, stimulate enterocinesia to cause laxative, thereby promote the discharge of intestinal endotoxin and other toxicants, lactulose also directly endotoxin in deactivation enteron aisle, reduce enteron aisle pH value, extensively model is applied to strengthen the treatment of child resistant;
Prebiotics of the present invention is 2 classes
A. external source probio is had to very strong field planting effect prebiotics: several or all mixing wherein of the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast;
B. common prebiotics: wherein a kind of, several of oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide or all mix;
Originally refer to a kind of, several or all mixing wherein of oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide.
5, carbohydrate: carbohydrate is by carbon, three kinds of elements of hydrogen and oxygen form, it be for human body provide three kinds of heat energy main nutrient in the most cheap nutrient, while taking in abundance, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA conveying hereditary information (DNA), and the glycogen containing in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms,
Carbohydrate of the present invention refers to a kind of, several or all mixing wherein of glucose, fructose, galactolipin, lactose, Arabinose, maltose, water-soluble dietary fiber, starch, glycogen.
6. amino acid: being divided into essential amino acid and nonessential amino acid, is the base unit that forms protein, gives protein specific molecular morphosis, makes it have biochemical activity; Absorbing appropriate methionine contributes to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and the effect of playing removing toxic substances; Leucine can be repaired muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress the growth of cancer knurl, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to the ammonia in blood change urea into and excrete out; For hyperammonemia, liver dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses alimentary canal nervous by vegetative nerve and that cause and festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improves sleep and regulates mood;
Amino acid of the present invention refers to a kind of, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.
7. vitamin and mineral matter:
Vitamin and mineral matter are the nutrients of needed by human, and the vitamin adding in the present invention is that vitamin and mineral matter are the nutrients of needed by human;
The vitamin adding in the present invention is a kind of, several or all mixing wherein of vitamin A, vitamin D, vitamin E, vitamin K, phytomenadione, vitamin C, vitamin B1, vitamin B2, pyridoxamine, cobalamin, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin;
The mineral matter adding in the present invention is a kind of, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;
In the present invention, the addition of vitamin and minerals is used sanitary standard > > with reference to GB14880 < < food enrichment, GB2760 < < food additives are used standard > > to carry out, and now take 1000g finished product as example, and addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.
8. the present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, mix with the Chinese medical extract after biological enzymolysis or the extraction of prehydrolysis SBE technology microencapsulation processing again, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and by gastric juice, arrive in enteron aisle and stop field planting smoothly by oral, make the effect of the anti-yellowing foxiness of product compare significantly raising with market like product.
9. adopt above-mentioned integrated innovation technique various batchings to be mixed to solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets the good production standard of < < special medicine purposes formula food > > requirement.
The characteristic of this full nutrient formulation food of filling a prescription and the effect of body is mainly manifested in to the following aspects:
1. the present invention is according to the requirement of < < special medicine purposes formula food general rule > >, constitutive character in conjunction with patient with chloasma, the achievement in research developments such as advanced physiology, medicine, nutrition and clinical practice of comprehensive nowadays American Harvard University, vary with each individual, gold compatibility.
2. the present invention is according to the marrow of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of " theoretical (liver,spleen,kidney three is dirty with being adjusted to main principle), adopting the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, take prebiotics, carbohydrate, amino acid, multivitamin and mineral matter as auxiliary material, the organic assembling of various batchings, various functions are merged, and by the synergy between active ingredient, humidification effect.
3. have efficient absorption, utilize formula of the present invention, various components adopt the food of suitable ratio collocation preparation, the state that oozes such as after a certain amount of water-soluble solution, be, can by stomach, arrive small intestine fast, absorption fast, completely, can supplement rapidly patient with chloasma desired nutritional.
4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicines, contain several functions active component, not only improved the concentration of function factor, reduce the absorption of various impurity, contribute to alleviate liver kidney burden, there is the effect that strengthens resistance of human body, delay senility in addition, promoting blood circulation, flat liver improving eyesight, menstruction regulating and pain relieving, cool blood disappear pain, relieving restlessness and strengthen the effect of immunity clears away heart-fire.
5. contained probio in the present invention formula, multiple probio can be safeguarded enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and the absorption of raising body to calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve the tolerance of host to radioactive ray, lactobacillus significantly increases intestinal mucosa immunoglobulin A (SIgA) content, body intestinal mucosa local immunity is had to regulating action, regulate stomach, the micro-ecology of intestines, can improve calcium, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, can also reduce the absorption of cholesterol.
6. to take the food source inhibition biological active small peptide in multiple source be nitrogenous source to formula food of the present invention, because small peptide does not need digestion to absorb, more be conducive to the utilization of body, can effectively improve patient with chloasma negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, the absorbability of raising intestinal mucosa.
7. this prescription adopts Liao Ben team by the achievement to the key technology research of probio field planting mechanism in enteron aisle over nearly 3 year, improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence that combines prebiotics can be played the reduction of field planting effect, enteron aisle pH environment and the key elements such as enteron aisle adhesive capacity of raising probiotic cell, so the composition of this food formula has strengthened the field planting effect to external source probio greatly.
8. contained prebiotics in the present invention formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; on intestinal mucosa surface, form one protective barrier simultaneously; can resist the damage of enteron aisle spoilage organisms to intestinal mucosa; reduce the absorption of intestinal toxic material; can also promote intestines peristalsis; accelerate the discharge of residuals in intestines; can prevent constipation; and by promoting the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.
9, in the present invention formula contained carbohydrate be for human body provide three kinds of heat energy main nutrient, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA (DNA) that conveys hereditary information, and the glycogen containing in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms.
10, contained amino acid in the present invention's formula, it is the base unit that forms protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and play the effect of removing toxic substances, can repair muscle, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.
11, formula food of the present invention containing multivitamin and mineral matter, can supplement rapidly the required micronutrient of patient with chloasma, small peptide by the chelating with calcium, iron, zinc etc. after, more increased the absorptivity of mineral matter element.
12, not fatty and cholesterol in the present invention's formula can not increase the absorption of fat, cholesterol in supplementary protein, micronutrient, has avoided the adverse effect of the high protein diets such as meat, egg.
The specific embodiment
Below by following examples, the invention will be further described, and it will contribute to understand the present invention.
Embodiment mono-
The full nutrient formulation food of realizing the object of the invention conditioning chloasma is with the constitutive character in conjunction with patient with chloasma, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, it is primary raw material that gold compatibility be take Chinese medical extract elite, multiple probio, the small peptide of 6 kinds of above medicine-food two-purposes, take the food that prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials make as auxiliary material;
By following raw materials according and consumption thereof, fill a prescription: the extract of medicine-food two-purpose: isoflavones 13g, grape seed extract 13g, safflower 12g, root of bidentate achyranthes 12g, motherwort 11g, red sage root 11g, Radix Angelicae Sinensis 11g, dendrobium candidum 11g, Cordyceps sinensis (aweto mycelium) 11g, lucidum spore powder (broken wall) 10g, Cordyceps militaris 10g, matrimony vine 10g, peach kernel 10g, mulberry fruit 8g, chrysanthemum 8g, cassia seed 4g, Poria cocos 4g, root of kudzu vine 4g, mulberry leaf 4g, rhizoma zingiberis 3g, root of Dahurain angelica 3g, mountain Cape jasmine 3g, aloe 3g, hawthorn 3g, pawpaw 2g, lotus leaf 2g, sea-buckthorn 2g, rose 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
First will be to be the stem of noble dendrobium during making, safflower, the root of bidentate achyranthes, motherwort, the red sage root, Radix Angelicae Sinensis, matrimony vine, mulberries, chrysanthemum, cassia seed, Poria cocos, the root of kudzu vine, mulberry leaf, rhizoma zingiberis, the root of Dahurain angelica, mountain Cape jasmine, aloe, hawthorn, pawpaw, lotus leaf, sea-buckthorn, rose, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, Gorgon fruit adds cycloheptaamylose after soaking, after extracting by prehydrolysis SBE technology, spray-dried and preparation flour, add again the small peptide that biological enzymolysis extracts, prebiotics, amino acid, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, carbohydrate, isoflavones, grape seed extract, lucidum spore powder (broken wall), peach kernel, after being pulverized and mixed together, multivitamin and mineral matter carry out pasteurization 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets the good production standard of < < special medicine purposes formula food > > requirement.
Embodiment bis-
The full nutrient formulation food of above-mentioned conditioning chloasma also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 19g, matrimony vine 18g, peach kernel 18g, mulberry fruit 18g, chrysanthemum 16g, cassia seed 15g, Poria cocos 15g, root of kudzu vine 15g, mulberry leaf 11g, rhizoma zingiberis 11g, root of Dahurain angelica 7g, mountain Cape jasmine 7g, aloe 7g, hawthorn 7g, pawpaw 4g, lotus leaf 4g, sea-buckthorn 4g, rose 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.
Embodiment tri-
The full nutrient formulation food of above-mentioned conditioning chloasma also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 19g, matrimony vine 18g, peach kernel 18g, mulberry fruit 18g, chrysanthemum 16g, cassia seed 15g, Poria cocos 15g, root of kudzu vine 15g, mulberry leaf 11g, rhizoma zingiberis 11g, root of Dahurain angelica 7g, mountain Cape jasmine 7g, aloe 7g, hawthorn 7g, pawpaw 4g, lotus leaf 4g, sea-buckthorn 4g, rose 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 150g, carbohydrate 100g.
The present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, mix with the Chinese medical extract after biological enzymolysis or the extraction of prehydrolysis SBE technology microencapsulation processing again, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and by gastric juice, arrived in enteron aisle and stopped field planting smoothly by oral, the effect that makes product prevent and treat chloasma is compared with market like product significantly and is improved.

Claims (9)

1. nurse one's health the full nutrient formulation food of chloasma, it is characterized in that with the constitutive character in conjunction with patient with chloasma, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, it is primary raw material that gold compatibility be take the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide, take the food that prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials make as auxiliary material;
By following raw materials according and consumption thereof, fill a prescription: the extract of medicine-food two-purpose: isoflavones 13g, grape seed extract 13g, safflower 12g, root of bidentate achyranthes 12g, motherwort 11g, red sage root 11g, Radix Angelicae Sinensis 11g, dendrobium candidum 11g, Cordyceps sinensis (aweto mycelium) 11g, lucidum spore powder (broken wall) 10g, Cordyceps militaris 10g, matrimony vine 10g, peach kernel 10g, mulberry fruit 8g, chrysanthemum 8g, cassia seed 4g, Poria cocos 4g, root of kudzu vine 4g, mulberry leaf 4g, rhizoma zingiberis 3g, root of Dahurain angelica 3g, mountain Cape jasmine 3g, aloe 3g, hawthorn 3g, pawpaw 2g, lotus leaf 2g, sea-buckthorn 2g, rose 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
Its preparation method is for first will be to be the stem of noble dendrobium, safflower, the root of bidentate achyranthes, motherwort, the red sage root, Radix Angelicae Sinensis, matrimony vine, mulberries, chrysanthemum, cassia seed, Poria cocos, the root of kudzu vine, mulberry leaf, rhizoma zingiberis, the root of Dahurain angelica, mountain Cape jasmine, aloe, hawthorn, pawpaw, lotus leaf, sea-buckthorn, rose, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, after soaking, Gorgon fruit adds cycloheptaamylose, after extracting by prehydrolysis SBE technology, and the spray-dried and flour of preparation, then add the small peptide that biological enzymolysis extracts, prebiotics, amino acid, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, carbohydrate, isoflavones, grape seed extract, lucidum spore powder (broken wall), peach kernel, multivitamin and mineral matter carry out pasteurization 1 hour after mixing, and then add the Bifidobacterium after microencapsulation, lactobacillus, the various batchings that streptococcus thermophilus also adds appropriate carbohydrate mixing again mix the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets the good production standard of < < special medicine purposes formula food > > requirement.
2. the full nutrient formulation food formula of conditioning chloasma according to claim 1, is characterized in that described medicine-food two-purpose Chinese herbal medicine extract is: the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, isoflavones, grape seed extract, safflower, the root of bidentate achyranthes, motherwort, the red sage root, Radix Angelicae Sinensis, lucidum spore powder (broken wall), matrimony vine, peach kernel, mulberries, chrysanthemum, cassia seed, Poria cocos, the root of kudzu vine, mulberry leaf, rhizoma zingiberis, the root of Dahurain angelica, mountain Cape jasmine, aloe, hawthorn, pawpaw, lotus leaf, sea-buckthorn, rose wherein two or more or all mix.
3. the full nutrient formulation food formula of conditioning chloasma according to claim 1, is characterised in that according to described formula and mixes and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food.
4. the full nutrient formulation food formula of conditioning chloasma according to claim 1, is characterized in that described prebiotics is. to external source probio, to have very strong field planting effect prebiotics be wherein several of extract, stachyose, yeast and common prebiotics of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke or all mix.
5. require the full nutrient formulation food formula of the conditioning chloasma described in 1, it is characterized in that described amino acid is a kind of, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.
6. the full nutrient formulation food formula of conditioning chloasma according to claim 1, is characterized in that described carbohydrate is a kind of, several or all mixing wherein of Arabinose, glucose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen.
7. the full nutrient formulation food formula of conditioning chloasma according to claim 1, is characterized in that being dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, mix with the Chinese medical extract after biological enzymolysis or the extraction of prehydrolysis SBE technology microencapsulation processing again, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and by gastric juice, arrived in enteron aisle and stopped field planting smoothly by oral, the effect that makes product prevent and treat chloasma is compared with market like product significantly and is improved.
8. the full nutrient formulation food formula of conditioning chloasma according to claim 1, is characterized in that described vitamin is a kind of, several or all mixing wherein of vitamin A, vitamin D, vitamin E, vitamin K, phytomenadione, vitamin C, vitamin B1, vitamin B2, pyridoxamine, cobalamin, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin; Described mineral matter is a kind of, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum.
9. the full nutrient formulation food formula of conditioning chloasma according to claim 1, is characterized in that described small peptide is wherein a kind of, several or all mixing of marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.
CN201410405420.8A 2014-08-18 2014-08-18 Fully nutrient formula food for recuperating chloasma Pending CN104146266A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016142767A1 (en) * 2015-03-09 2016-09-15 Bioimmunizer Sagl Anti-age composition comprising a combination of antioxidant agents in association with bifidobacteria and cell walls isolated from probiotics
CN109157570A (en) * 2018-11-29 2019-01-08 江西济民可信金水宝制药有限公司 A kind of complex capsule
CN111700953A (en) * 2020-06-23 2020-09-25 珠海宝德润生健康科技有限公司 Freckle removing composition and preparation method and application thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016142767A1 (en) * 2015-03-09 2016-09-15 Bioimmunizer Sagl Anti-age composition comprising a combination of antioxidant agents in association with bifidobacteria and cell walls isolated from probiotics
CN107567333A (en) * 2015-03-09 2018-01-09 生物免疫Sagl公司 The anti-apolexis composition of the cell membrane separated comprising antioxidant with Bifidobacterium and from probiotics
CN109157570A (en) * 2018-11-29 2019-01-08 江西济民可信金水宝制药有限公司 A kind of complex capsule
CN111700953A (en) * 2020-06-23 2020-09-25 珠海宝德润生健康科技有限公司 Freckle removing composition and preparation method and application thereof

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RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20141119