CN104187741A - Total nutrient formula food for heart disease - Google Patents
Total nutrient formula food for heart disease Download PDFInfo
- Publication number
- CN104187741A CN104187741A CN201410402257.XA CN201410402257A CN104187741A CN 104187741 A CN104187741 A CN 104187741A CN 201410402257 A CN201410402257 A CN 201410402257A CN 104187741 A CN104187741 A CN 104187741A
- Authority
- CN
- China
- Prior art keywords
- food
- vitamin
- heart disease
- medicine
- probio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000013305 food Nutrition 0.000 title claims abstract description 60
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 41
- 208000019622 heart disease Diseases 0.000 title claims abstract description 35
- 239000003814 drug Substances 0.000 claims abstract description 40
- 239000000284 extract Substances 0.000 claims abstract description 28
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 26
- 235000013406 prebiotics Nutrition 0.000 claims abstract description 23
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 22
- 239000011707 mineral Substances 0.000 claims abstract description 22
- 150000001413 amino acids Chemical class 0.000 claims abstract description 21
- 239000000463 material Substances 0.000 claims abstract description 20
- 238000002156 mixing Methods 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 229940088594 vitamin Drugs 0.000 claims abstract description 9
- 229930003231 vitamin Natural products 0.000 claims abstract description 9
- 235000013343 vitamin Nutrition 0.000 claims abstract description 9
- 239000011782 vitamin Substances 0.000 claims abstract description 9
- 108010038807 Oligopeptides Proteins 0.000 claims abstract description 6
- 102000015636 Oligopeptides Human genes 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 42
- 230000000694 effects Effects 0.000 claims description 33
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 32
- 238000009472 formulation Methods 0.000 claims description 28
- 235000014633 carbohydrates Nutrition 0.000 claims description 24
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 20
- 229940024606 amino acid Drugs 0.000 claims description 20
- 235000001014 amino acid Nutrition 0.000 claims description 20
- 235000013399 edible fruits Nutrition 0.000 claims description 19
- 238000005516 engineering process Methods 0.000 claims description 19
- 240000002853 Nelumbo nucifera Species 0.000 claims description 15
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 15
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 15
- 230000000747 cardiac effect Effects 0.000 claims description 14
- 244000268590 Euryale ferox Species 0.000 claims description 13
- 235000006487 Euryale ferox Nutrition 0.000 claims description 13
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims description 13
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 12
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 12
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 12
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 12
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 12
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 12
- 235000018102 proteins Nutrition 0.000 claims description 12
- 108090000623 proteins and genes Proteins 0.000 claims description 12
- 102000004169 proteins and genes Human genes 0.000 claims description 12
- NHZMQXZHNVQTQA-UHFFFAOYSA-N pyridoxamine Chemical compound CC1=NC=C(CO)C(CN)=C1O NHZMQXZHNVQTQA-UHFFFAOYSA-N 0.000 claims description 12
- 241000186660 Lactobacillus Species 0.000 claims description 11
- 230000035622 drinking Effects 0.000 claims description 11
- 235000008216 herbs Nutrition 0.000 claims description 11
- 230000010354 integration Effects 0.000 claims description 11
- 229940039696 lactobacillus Drugs 0.000 claims description 11
- 239000000843 powder Substances 0.000 claims description 11
- 229940079593 drug Drugs 0.000 claims description 10
- 229910052742 iron Inorganic materials 0.000 claims description 10
- 235000013557 nattō Nutrition 0.000 claims description 10
- 241000186000 Bifidobacterium Species 0.000 claims description 9
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 9
- 240000001008 Dimocarpus longan Species 0.000 claims description 9
- 235000000235 Euphoria longan Nutrition 0.000 claims description 9
- 241000234435 Lilium Species 0.000 claims description 9
- 244000241838 Lycium barbarum Species 0.000 claims description 9
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 9
- 241000218231 Moraceae Species 0.000 claims description 9
- 235000008708 Morus alba Nutrition 0.000 claims description 9
- 244000197580 Poria cocos Species 0.000 claims description 9
- 235000008599 Poria cocos Nutrition 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 9
- 229910052791 calcium Inorganic materials 0.000 claims description 9
- 239000011575 calcium Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 244000037364 Cinnamomum aromaticum Species 0.000 claims description 8
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims description 8
- 241000756943 Codonopsis Species 0.000 claims description 8
- 241001264174 Cordyceps militaris Species 0.000 claims description 8
- 240000004371 Panax ginseng Species 0.000 claims description 8
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 8
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 8
- 244000046146 Pueraria lobata Species 0.000 claims description 8
- 235000010575 Pueraria lobata Nutrition 0.000 claims description 8
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 8
- 235000008434 ginseng Nutrition 0.000 claims description 8
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 8
- 239000011701 zinc Substances 0.000 claims description 8
- 229910052725 zinc Inorganic materials 0.000 claims description 8
- 235000011201 Ginkgo Nutrition 0.000 claims description 7
- 244000194101 Ginkgo biloba Species 0.000 claims description 7
- 235000008100 Ginkgo biloba Nutrition 0.000 claims description 7
- 239000009636 Huang Qi Substances 0.000 claims description 7
- 241000112528 Ligusticum striatum Species 0.000 claims description 7
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 7
- 241000194020 Streptococcus thermophilus Species 0.000 claims description 7
- 229930003316 Vitamin D Natural products 0.000 claims description 7
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 7
- 229930003448 Vitamin K Natural products 0.000 claims description 7
- 235000013361 beverage Nutrition 0.000 claims description 7
- 239000011574 phosphorus Substances 0.000 claims description 7
- 229910052698 phosphorus Inorganic materials 0.000 claims description 7
- 235000019166 vitamin D Nutrition 0.000 claims description 7
- 239000011710 vitamin D Substances 0.000 claims description 7
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 7
- 235000019168 vitamin K Nutrition 0.000 claims description 7
- 239000011712 vitamin K Substances 0.000 claims description 7
- 150000003721 vitamin K derivatives Chemical class 0.000 claims description 7
- 229940046008 vitamin d Drugs 0.000 claims description 7
- 229940046010 vitamin k Drugs 0.000 claims description 7
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 6
- 241001412627 Adenophora liliifolia Species 0.000 claims description 6
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 6
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 6
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 6
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 6
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 6
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 6
- 240000004638 Dendrobium nobile Species 0.000 claims description 6
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 6
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 6
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 6
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 6
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims description 6
- 241000222336 Ganoderma Species 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 6
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims description 6
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 6
- 241001248610 Ophiocordyceps sinensis Species 0.000 claims description 6
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 6
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 6
- 240000006079 Schisandra chinensis Species 0.000 claims description 6
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 6
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 6
- 229930003471 Vitamin B2 Natural products 0.000 claims description 6
- 229930003268 Vitamin C Natural products 0.000 claims description 6
- 229930003427 Vitamin E Natural products 0.000 claims description 6
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 6
- 229960002685 biotin Drugs 0.000 claims description 6
- 235000020958 biotin Nutrition 0.000 claims description 6
- 239000011616 biotin Substances 0.000 claims description 6
- 239000000460 chlorine Substances 0.000 claims description 6
- 229910052801 chlorine Inorganic materials 0.000 claims description 6
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims description 6
- 229960001231 choline Drugs 0.000 claims description 6
- 229910052804 chromium Inorganic materials 0.000 claims description 6
- 239000011651 chromium Substances 0.000 claims description 6
- 239000010949 copper Substances 0.000 claims description 6
- 229910052802 copper Inorganic materials 0.000 claims description 6
- 239000011737 fluorine Substances 0.000 claims description 6
- 229910052731 fluorine Inorganic materials 0.000 claims description 6
- 229960000304 folic acid Drugs 0.000 claims description 6
- 235000019152 folic acid Nutrition 0.000 claims description 6
- 239000011724 folic acid Substances 0.000 claims description 6
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 6
- 210000004051 gastric juice Anatomy 0.000 claims description 6
- 239000011777 magnesium Substances 0.000 claims description 6
- 229910052749 magnesium Inorganic materials 0.000 claims description 6
- 239000003094 microcapsule Substances 0.000 claims description 6
- 229910052750 molybdenum Inorganic materials 0.000 claims description 6
- 239000011733 molybdenum Substances 0.000 claims description 6
- 229960003512 nicotinic acid Drugs 0.000 claims description 6
- 235000001968 nicotinic acid Nutrition 0.000 claims description 6
- 239000011664 nicotinic acid Substances 0.000 claims description 6
- 229940055726 pantothenic acid Drugs 0.000 claims description 6
- 235000019161 pantothenic acid Nutrition 0.000 claims description 6
- 239000011713 pantothenic acid Substances 0.000 claims description 6
- 235000019175 phylloquinone Nutrition 0.000 claims description 6
- 239000011772 phylloquinone Substances 0.000 claims description 6
- MBWXNTAXLNYFJB-NKFFZRIASA-N phylloquinone Chemical compound C1=CC=C2C(=O)C(C/C=C(C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C)C(=O)C2=C1 MBWXNTAXLNYFJB-NKFFZRIASA-N 0.000 claims description 6
- 229960001898 phytomenadione Drugs 0.000 claims description 6
- 239000011591 potassium Substances 0.000 claims description 6
- 229910052700 potassium Inorganic materials 0.000 claims description 6
- 235000008151 pyridoxamine Nutrition 0.000 claims description 6
- 239000011699 pyridoxamine Substances 0.000 claims description 6
- 229960002477 riboflavin Drugs 0.000 claims description 6
- 229910052711 selenium Inorganic materials 0.000 claims description 6
- 239000011669 selenium Substances 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- 235000019155 vitamin A Nutrition 0.000 claims description 6
- 239000011719 vitamin A Substances 0.000 claims description 6
- 235000019164 vitamin B2 Nutrition 0.000 claims description 6
- 239000011716 vitamin B2 Substances 0.000 claims description 6
- 235000019154 vitamin C Nutrition 0.000 claims description 6
- 239000011718 vitamin C Substances 0.000 claims description 6
- 235000019165 vitamin E Nutrition 0.000 claims description 6
- 229940046009 vitamin E Drugs 0.000 claims description 6
- 239000011709 vitamin E Substances 0.000 claims description 6
- 229940045997 vitamin a Drugs 0.000 claims description 6
- 241000287828 Gallus gallus Species 0.000 claims description 5
- 239000002775 capsule Substances 0.000 claims description 5
- -1 citrulling Chemical compound 0.000 claims description 5
- 210000004317 gizzard Anatomy 0.000 claims description 5
- 241000411851 herbal medicine Species 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 4
- 229920002527 Glycogen Polymers 0.000 claims description 4
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims description 4
- UQZIYBXSHAGNOE-USOSMYMVSA-N Stachyose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](CO[C@@H]2[C@@H](O)[C@@H](O)[C@@H](O)[C@H](CO)O2)O1 UQZIYBXSHAGNOE-USOSMYMVSA-N 0.000 claims description 4
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 4
- 230000009849 deactivation Effects 0.000 claims description 4
- 239000008103 glucose Substances 0.000 claims description 4
- 229940096919 glycogen Drugs 0.000 claims description 4
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 4
- 229910052737 gold Inorganic materials 0.000 claims description 4
- 239000010931 gold Substances 0.000 claims description 4
- 239000011630 iodine Substances 0.000 claims description 4
- 229910052740 iodine Inorganic materials 0.000 claims description 4
- 229910052748 manganese Inorganic materials 0.000 claims description 4
- 239000011572 manganese Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- UQZIYBXSHAGNOE-XNSRJBNMSA-N stachyose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)O2)O)O1 UQZIYBXSHAGNOE-XNSRJBNMSA-N 0.000 claims description 4
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 239000004475 Arginine Substances 0.000 claims description 3
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims description 3
- 240000008892 Helianthus tuberosus Species 0.000 claims description 3
- 235000003230 Helianthus tuberosus Nutrition 0.000 claims description 3
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims description 3
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims description 3
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims description 3
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 3
- 239000004472 Lysine Substances 0.000 claims description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 3
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims description 3
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 235000015895 biscuits Nutrition 0.000 claims description 3
- 235000007215 black sesame Nutrition 0.000 claims description 3
- 230000003203 everyday effect Effects 0.000 claims description 3
- 235000003599 food sweetener Nutrition 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 3
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 235000012054 meals Nutrition 0.000 claims description 3
- 229930182817 methionine Natural products 0.000 claims description 3
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 238000005507 spraying Methods 0.000 claims description 3
- 239000003765 sweetening agent Substances 0.000 claims description 3
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 2
- 102000008186 Collagen Human genes 0.000 claims description 2
- 108010035532 Collagen Proteins 0.000 claims description 2
- WHGYBXFWUBPSRW-UHFFFAOYSA-N Cycloheptaamylose Natural products O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO WHGYBXFWUBPSRW-UHFFFAOYSA-N 0.000 claims description 2
- 229930091371 Fructose Natural products 0.000 claims description 2
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 2
- 239000005715 Fructose Substances 0.000 claims description 2
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 claims description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims description 2
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims description 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims description 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims description 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims description 2
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 claims description 2
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 claims description 2
- 108010073771 Soybean Proteins Proteins 0.000 claims description 2
- 229920002472 Starch Polymers 0.000 claims description 2
- 235000021307 Triticum Nutrition 0.000 claims description 2
- 244000098338 Triticum aestivum Species 0.000 claims description 2
- 229930003451 Vitamin B1 Natural products 0.000 claims description 2
- 108010046377 Whey Proteins Proteins 0.000 claims description 2
- 102000007544 Whey Proteins Human genes 0.000 claims description 2
- 240000008042 Zea mays Species 0.000 claims description 2
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 claims description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 2
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 2
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims description 2
- 210000000988 bone and bone Anatomy 0.000 claims description 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims description 2
- 229920001436 collagen Polymers 0.000 claims description 2
- 235000013325 dietary fiber Nutrition 0.000 claims description 2
- 235000013312 flour Nutrition 0.000 claims description 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims description 2
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims description 2
- 229960000310 isoleucine Drugs 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- 235000009973 maize Nutrition 0.000 claims description 2
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims description 2
- 229960003104 ornithine Drugs 0.000 claims description 2
- GSSMIHQEWAQUPM-AOLPDKKJSA-N ovalbumin peptide Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C1=CN=CN1 GSSMIHQEWAQUPM-AOLPDKKJSA-N 0.000 claims description 2
- 238000009928 pasteurization Methods 0.000 claims description 2
- 238000002791 soaking Methods 0.000 claims description 2
- 229940001941 soy protein Drugs 0.000 claims description 2
- 235000019698 starch Nutrition 0.000 claims description 2
- 239000008107 starch Substances 0.000 claims description 2
- 229960003080 taurine Drugs 0.000 claims description 2
- 229960003495 thiamine Drugs 0.000 claims description 2
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 2
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims description 2
- 235000010374 vitamin B1 Nutrition 0.000 claims description 2
- 239000011691 vitamin B1 Substances 0.000 claims description 2
- 235000021119 whey protein Nutrition 0.000 claims description 2
- 230000006870 function Effects 0.000 abstract description 21
- 210000004369 blood Anatomy 0.000 abstract description 16
- 239000008280 blood Substances 0.000 abstract description 16
- 235000016709 nutrition Nutrition 0.000 abstract description 12
- 238000011160 research Methods 0.000 abstract description 12
- 210000000952 spleen Anatomy 0.000 abstract description 11
- 210000004185 liver Anatomy 0.000 abstract description 9
- 230000017531 blood circulation Effects 0.000 abstract description 6
- 230000002708 enhancing effect Effects 0.000 abstract description 6
- 210000003734 kidney Anatomy 0.000 abstract description 6
- 230000001737 promoting effect Effects 0.000 abstract description 6
- 239000000126 substance Substances 0.000 abstract description 5
- 230000004089 microcirculation Effects 0.000 abstract description 4
- 239000006041 probiotic Substances 0.000 abstract description 4
- 235000018291 probiotics Nutrition 0.000 abstract description 4
- 230000001105 regulatory effect Effects 0.000 abstract description 4
- 210000004204 blood vessel Anatomy 0.000 abstract description 3
- 230000035479 physiological effects, processes and functions Effects 0.000 abstract description 3
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000003394 haemopoietic effect Effects 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 description 18
- UYPYRKYUKCHHIB-UHFFFAOYSA-N trimethylamine N-oxide Chemical compound C[N+](C)(C)[O-] UYPYRKYUKCHHIB-UHFFFAOYSA-N 0.000 description 13
- 201000010099 disease Diseases 0.000 description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 12
- 230000036039 immunity Effects 0.000 description 11
- 230000012010 growth Effects 0.000 description 10
- 239000000047 product Substances 0.000 description 10
- 241000894006 Bacteria Species 0.000 description 9
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 8
- 210000001035 gastrointestinal tract Anatomy 0.000 description 8
- 230000000968 intestinal effect Effects 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 7
- 210000000936 intestine Anatomy 0.000 description 7
- 230000035764 nutrition Effects 0.000 description 7
- 206010020772 Hypertension Diseases 0.000 description 5
- 238000011161 development Methods 0.000 description 5
- 230000018109 developmental process Effects 0.000 description 5
- 230000029087 digestion Effects 0.000 description 5
- 210000004347 intestinal mucosa Anatomy 0.000 description 5
- 230000004060 metabolic process Effects 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 231100000331 toxic Toxicity 0.000 description 5
- 230000002588 toxic effect Effects 0.000 description 5
- 238000009395 breeding Methods 0.000 description 4
- 230000001488 breeding effect Effects 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 235000012000 cholesterol Nutrition 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 208000010125 myocardial infarction Diseases 0.000 description 4
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 208000031229 Cardiomyopathies Diseases 0.000 description 3
- 206010033799 Paralysis Diseases 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 208000029078 coronary artery disease Diseases 0.000 description 3
- 206010012601 diabetes mellitus Diseases 0.000 description 3
- 235000013601 eggs Nutrition 0.000 description 3
- 230000011132 hemopoiesis Effects 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 210000004379 membrane Anatomy 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 208000021090 palsy Diseases 0.000 description 3
- 230000000529 probiotic effect Effects 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 210000000813 small intestine Anatomy 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical group O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000186016 Bifidobacterium bifidum Species 0.000 description 2
- 208000002330 Congenital Heart Defects Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 2
- 235000010469 Glycine max Nutrition 0.000 description 2
- 229930186217 Glycolipid Natural products 0.000 description 2
- 102000003886 Glycoproteins Human genes 0.000 description 2
- 108090000288 Glycoproteins Proteins 0.000 description 2
- 206010021143 Hypoxia Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 230000001142 anti-diarrhea Effects 0.000 description 2
- 208000011775 arteriosclerosis disease Diseases 0.000 description 2
- 229940002008 bifidobacterium bifidum Drugs 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- 208000028831 congenital heart disease Diseases 0.000 description 2
- HEBKCHPVOIAQTA-NGQZWQHPSA-N d-xylitol Chemical compound OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 description 2
- 238000001784 detoxification Methods 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 235000021245 dietary protein Nutrition 0.000 description 2
- 239000002158 endotoxin Substances 0.000 description 2
- 235000020776 essential amino acid Nutrition 0.000 description 2
- 239000003797 essential amino acid Substances 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 201000010235 heart cancer Diseases 0.000 description 2
- 208000024348 heart neoplasm Diseases 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 210000005229 liver cell Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 244000000010 microbial pathogen Species 0.000 description 2
- 239000011785 micronutrient Substances 0.000 description 2
- 235000013369 micronutrients Nutrition 0.000 description 2
- 230000036651 mood Effects 0.000 description 2
- 210000004165 myocardium Anatomy 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 210000004126 nerve fiber Anatomy 0.000 description 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 2
- 235000008935 nutritious Nutrition 0.000 description 2
- 229920001542 oligosaccharide Polymers 0.000 description 2
- 150000002482 oligosaccharides Chemical class 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 208000002815 pulmonary hypertension Diseases 0.000 description 2
- 208000004124 rheumatic heart disease Diseases 0.000 description 2
- 229910052717 sulfur Inorganic materials 0.000 description 2
- 239000011593 sulfur Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- 108010022579 ATP dependent 26S protease Proteins 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 206010002660 Anoxia Diseases 0.000 description 1
- 241000976983 Anoxia Species 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000186018 Bifidobacterium adolescentis Species 0.000 description 1
- 241000901050 Bifidobacterium animalis subsp. lactis Species 0.000 description 1
- 241000186012 Bifidobacterium breve Species 0.000 description 1
- 241001608472 Bifidobacterium longum Species 0.000 description 1
- 241000186015 Bifidobacterium longum subsp. infantis Species 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 1
- 201000006306 Cor pulmonale Diseases 0.000 description 1
- 206010010970 Cor pulmonale chronic Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 208000037487 Endotoxemia Diseases 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 206010020575 Hyperammonaemia Diseases 0.000 description 1
- 206010020850 Hyperthyroidism Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- 244000199885 Lactobacillus bulgaricus Species 0.000 description 1
- 235000013960 Lactobacillus bulgaricus Nutrition 0.000 description 1
- 244000199866 Lactobacillus casei Species 0.000 description 1
- 235000013958 Lactobacillus casei Nutrition 0.000 description 1
- 241000186673 Lactobacillus delbrueckii Species 0.000 description 1
- 241000186840 Lactobacillus fermentum Species 0.000 description 1
- 241000186606 Lactobacillus gasseri Species 0.000 description 1
- 240000002605 Lactobacillus helveticus Species 0.000 description 1
- 235000013967 Lactobacillus helveticus Nutrition 0.000 description 1
- 240000006024 Lactobacillus plantarum Species 0.000 description 1
- 235000013965 Lactobacillus plantarum Nutrition 0.000 description 1
- 241000186604 Lactobacillus reuteri Species 0.000 description 1
- 241000218588 Lactobacillus rhamnosus Species 0.000 description 1
- 241000186869 Lactobacillus salivarius Species 0.000 description 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 1
- 206010067125 Liver injury Diseases 0.000 description 1
- 206010028851 Necrosis Diseases 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 206010029400 Nicotinic acid deficiency Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 208000002141 Pellagra Diseases 0.000 description 1
- 208000004186 Pulmonary Heart Disease Diseases 0.000 description 1
- 229930189077 Rifamycin Natural products 0.000 description 1
- 206010039163 Right ventricular failure Diseases 0.000 description 1
- 208000000924 Right ventricular hypertrophy Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 108010046334 Urease Proteins 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000007953 anoxia Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 229940004120 bifidobacterium infantis Drugs 0.000 description 1
- 229940009289 bifidobacterium lactis Drugs 0.000 description 1
- 229940009291 bifidobacterium longum Drugs 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 230000005907 cancer growth Effects 0.000 description 1
- 208000035269 cancer or benign tumor Diseases 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 229960004203 carnitine Drugs 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 235000020774 essential nutrients Nutrition 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 210000003709 heart valve Anatomy 0.000 description 1
- 231100000753 hepatic injury Toxicity 0.000 description 1
- 235000008085 high protein diet Nutrition 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 229940099472 immunoglobulin a Drugs 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- 210000002490 intestinal epithelial cell Anatomy 0.000 description 1
- 208000028867 ischemia Diseases 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 229940004208 lactobacillus bulgaricus Drugs 0.000 description 1
- 229940017800 lactobacillus casei Drugs 0.000 description 1
- 229940054346 lactobacillus helveticus Drugs 0.000 description 1
- 229940072205 lactobacillus plantarum Drugs 0.000 description 1
- 229940001882 lactobacillus reuteri Drugs 0.000 description 1
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 1
- 229960000511 lactulose Drugs 0.000 description 1
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 231100000225 lethality Toxicity 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 230000005976 liver dysfunction Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000007659 motor function Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 239000000712 neurohormone Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 235000021075 protein intake Nutrition 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000036593 pulmonary vascular resistance Effects 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000010410 reperfusion Effects 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 229960003292 rifamycin Drugs 0.000 description 1
- HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical compound OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 description 1
- NZCRJKRKKOLAOJ-XRCRFVBUSA-N rifaximin Chemical compound OC1=C(C(O)=C2C)C3=C4N=C5C=C(C)C=CN5C4=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O NZCRJKRKKOLAOJ-XRCRFVBUSA-N 0.000 description 1
- 229960003040 rifaximin Drugs 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 231100000216 vascular lesion Toxicity 0.000 description 1
- 230000006439 vascular pathology Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 235000020795 whole food diet Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/21—Streptococcus, lactococcus
- A23V2400/249—Thermophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
Abstract
The invention discloses total nutrient formula food, specific total nutrient formula food or non-total nutrient formula food for patients with heart disease. The formula, as required by Food for Special Medical Purposes (FSMP), is developed in combination with physical characteristics of patients with heart disease as well as current research results of Harvard University in the US on advanced physiology, medicine and pharmacology, nutriology, clinical application, and the like in accordance with essential theory (based on principle of simultaneously regulating liver, spleen and kidney) of traditional Chinese medicine of'elimination for tonifying' and'balanced nourishing'. The finished product is prepared by mixing raw materials mainly including essence of extracts of various medicinal and edible traditional Chinese medicines, a plurality of probiotics and oligopeptide as well as auxiliary materials such as prebiotics, carbohydrate, amino acid, multiple vitamins and mineral substances. The food not only can be as a single nutrient source to meet nutritional requirements of patients with heart disease, but also has the functions of promoting blood circulation to remove blood stasis, clearing away heat fire and refreshing spleen, nourishing vital energy, dilating blood vessels, reducing blood pressure, improving microcirculation and enhancing hematopoietic function.
Description
Technical field
The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " medicine among integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds the full nutrient formulation food of heart disease, specific full nutrient formulation food or the non-full nutrient formulation food made as auxiliary material taking small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter.
Background technology
Heart disease is the more common circulation system disease of a class, the circulatory system is by heart, blood vessel and the sanguimotor neurohumor organizational composition of adjusting, circulation system disease is also referred to as cardiovascular disease, comprise the disease of above-mentioned all histoorgans, in internal disease, belong to common disease, wherein common with heart disease, can affect significantly patient's labour, heart disease (heart disease) is the general name of heart disease, comprise rheumatic heart disease, congenital heart disease, restricted type heart disease, chronic cor pulmonale, hypertensive cerebral cardiomyopathy, hyperthyroid heart disease, diabetic cardiopathy, high altitude heart disease, coronary heart disease, the various heart diseases such as cardiomyopathy, the cause of heart disease: one, congenital heart disease: may be relevant in the disease of early pregnancy or the medicine taken due to mother, relevant with heredity, two, coronary heart disease: smoke and diabetes, hypertension etc. cause vascular sclerosis narrow, and blood flow is obstructed, and easily make myocardial anoxia and impaired, three, rheumatic heart disease: mainly, after rheumatic fever infects, cardiac valves gradually pathology causes abnormal, four, cor pulmonale: due to pulmonary vascular resistance increase, pulmonary hypertension due to lung, thorax or pulmonary arterial vascular pathology and then make Right ventricular hypertrophy, expansion, the heart disease of right heart failure even occurs, five, cardiomyopathy: the cardiac muscle variation that metabolism or hormone are abnormal etc., excessive drinking sometimes, medicine also causes cardiac muscle to change, six, cardiac tumor: cardiac tumor surface patches or thrombus come off and cause embolism.May be relevant with the product of tumour, neoplasm necrosis or immune response; Seven, the heart disease that other diseases causes: comprise vascular lesion that hypertension and other immunity function cause extremely etc.; Eight, the impact of extraneous factor: the pulmonary hypertension that chronic hypobaric hypoxia causes, infect the heart change causing, " integration of drinking and medicinal herbs " is one of contribution to mankind's most worthy among Chinese original medical science; The traditional Chinese medical science always emphasize " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet; Allow people dispel slight illness in the process of enjoying cuisines, avoided having an injection, taking medicine, even the hardship of operation.
For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And wholefood clearly specifies in China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: the full nutrient formulation food of 2.1.1: the special medicine purposes formula food that can be used as single source of nutrition and meet target group's nutritional need; 2.1.2 specific full nutrient formulation food: the special medicine purposes formula food that can be used as single source of nutrition and meet target group's nutritional need under specified disease or medical condition.
Traditional Chinese medical science traditional medicine is thought: " spleen (being digestive system) is the foundation of acquired constitution ", stomach health is healthy basis, and 99% of human nutrition need to lean on intestinal absorption, and in intestines, disease is also the source of ten thousand diseases; But along with the age is larger, profitable strain in enteron aisle (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% period infant, during to the middle age, be down to and only account for 5% in 10%, 65 years old later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies show that, normal flora has many irreplaceable effects in human body digestion, immunity and the aspect such as disease-resistant; The generation development of change and the various diseases, particularly intestines problem of gut flora composition is closely related, and finds from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one is intervened control method safely and effectively.
The relation of heart disease and gut flora: one that is published in " he New England Journal of Medicine " on April 25th, 2013 studies show that, a kind of microorganism accessory substance of enteric bacteria can cause heart disease, and can be as prediction heart attack in the future in the crowd by conventional risk factors and blood testing None-identified, the accurate screening instruments of one of palsy and mortality risk, this research team is taken the lead by Stanley doctor Hazen and W.H. Wilson doctor Tang and to the research before doctor Hazen is expanded, in research before, when doctor Hazen finds enteric bacteria digestion nutrients lecithin (being often called phosphatid ylcholine), produce the accessory substance that one is called TMAO (TMAO), previously studies show that, TMAO level in blood is relevant to heart disease, doctor Hazen and colleague have now confirmed that gut flora forms in TMAO process and is absolutely necessary the mankind, and proved TMAO level with cardiac event in the future (as heart attack, palsy and death) between there is correlation, even still like this in not previously being in the mood for popular name for risk evidence person, in order to prove the effect of gut flora in TMAO forms, experimenter's be required to take food phosphatid ylcholine capsule (as tracer) of 2 eggs that boil (the common dietary source of one of phosphatid ylcholine) and a mark, take in after egg, TMAO level in blood increases, but, in the time that these identical experimenters are given short-term broad-spectrum antibiotic inhibition gut flora, their TMAO level is suppressed, and do not have more TMAO to form, even still like this after absorption phosphatid ylcholine, these results show, enteric bacteria is essential by TMAO forms, in the second stage of research, researcher is large-scale to one, separately, after following up a case by regular visits to the TMAO level of having measured afterwards experimenter for 3 years, clinical queue (comprising more than 4000 adult who carries out heart assessment in Cleveland hospital) finds, blood TMAO level is higher dead to 3 years subsequently and non-lethality is had a heart attack or palsy risk is higher relevant, these results have been proved the result of doctor's Hazen another research recently: a kind of metabolism of the structural similarity nutrients (carnitine) that sees animal product is produced with TMAO gut flora and heart attack risk is associated.
Though directly probiotic oral has certain effect, but because probio one cannot field planting in enteron aisle, and stop, occupy-place are little, easily run off, and withdraw rear harmful bacteria and easily recur, and associated patient needs long-term taking, and treatment cycle is long, often uses rear recurrence rate very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts to seek to improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can be played field planting effect, the enteron aisle adhesive capacity of the reduction of enteron aisle pH environment and raising probiotic cell etc., based on above-mentioned key element, suitable food materials screen from tens of kinds " medicines among integration of drinking and medicinal herbs " in this seminar, find first interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and jerusalem artichoke and stachyose, yeast, after Glu etc., external source probio is had to very strong field planting effect, for the prescription of probio in enteral microecological formulation selects to provide experimental basis.
Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter composition compound prescription, utilize in addition the product that probio is primary raw material, but also do not find the constitutive character in conjunction with cardiac, according to the marrow theory of Traditional Chinese Medicine, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials is the full nutrient formulation food that auxiliary material is made, specific full nutrient formulation food or similar products.
goal of the invention
The object of the invention is inheriting on the theoretical treatment method of traditional Chinese medical science marrow, the initiative extract by multiple raising cardiac immunity probio and " medicine among integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, not only can supplement cardiac institute essential nutrients, improve body nutrition condition, can also and utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutrient formulation food that the acceptable applicable cardiac of people eats, specific full nutrient formulation food or non-full nutrient formulation food.
summary of the invention:
This R&D team is according to the requirement of " special medicine purposes formula food general rule ", in conjunction with cardiac's constitutive character, the comprehensively advanced physiology of nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears is mended ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets cardiac, also has promoting blood circulation, clear away heart-fire and be amusing, nourishing vigour, hemangiectasis, step-down, improve the full nutrient formulation food of microcirculation and enhancing hematopoiesis function, specific full nutrient formulation food or non-full nutrient formulation food (compound prescription being combined into).
1, the main component of the present invention's formula is:
Chinese medical extract is that the liver,spleen,kidney three from theory of traditional Chinese medical science is dirty with being adjusted to main principle according to cardiac's constitutive character, utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and choose following several large class medicine and carry out compatibility; Wherein: Radix Astragali taste is light, therefore specially divide and reach table in gas, so energy complement sun fills space between skin and muscles, control internal lesion caused by overexertion, longue meat; Ginkgo has the function of the phlegm of falling, detoxicating, desinsection, can treat that sore scabies subcutaneous ulcer knurl, acute mastitis are festered, tooth worm dental caries; Ligusticum wallichii is promoting the circulation of qi, the medicine that dispels the wind, and has promoting blood circulation; Activating QI to alleviate the depression; Effect of wind-expelling pain-stopping; Radix Codonopsis Radix Codonopsis is containing various saccharides, phenols, sterol, saponin and Alkaloid, has to strengthen immunity, hemangiectasis, step-down, improve microcirculation, strengthen the effect of hematopoiesis function; Radix Angelicae Sinensis has the effect of enriching blood and invigorating blood circulation, and has effect antibacterial, anti arteriosclerosis; Lily sweet and slightly bitter taste, property is flat, enters the heart, lung channel, have moisten the lung and relieve the cough, the merit of clearing away the heart fire and tranquillizing; The mulberries spleen that can increase weight, strengthens hemolytic reaction, promotes the growth of erythrocyte, prevents that leucocyte from reducing, and the illnesss such as treatment diabetes, anaemia, hypertension, high fat of blood, coronary heart disease, neurasthenia are had to auxiliary effect; Spina date seed has nourishing the liver, and Ning Xin calms the nerves, the effect of arrest sweating; Lotus seeds enter spleen, kidney, the heart channel of Hang-Shaoyin, and having clears away heart-fire is amusing, tonifying spleen antidiarrheal, and mental-tranquilization improving eyesight, bowl spares are reposed, stomach, antidiarrheal controlling nocturnal emission with astringent drugs, kidney-nourishing relieving leukorrhea by astringents are mended in invigorating the spleen, effect of nourishing vigour; Arillus longan has tonifying heart and spleen, and the effect of nourishing blood and tranquilization, for insufficiency of vital energy and blood, palpitation and severe palpitation, forgetful insomnia; In natto, be rich in the blue or green element of soap, can improve constipation, reduce blood fat, prevention colorectal cancer, reduction cholesterol, softening blood vessel, preventing hypertension and artery sclerosis;
Medicinal and edible Chinese medicine extract of the present invention refer to the Radix Astragali, ginkgo, Ligusticum wallichii, Radix Codonopsis, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, the root of straight ladybell, the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), glossy ganoderma, Cordyceps militaris, matrimony vine, Gorgon fruit, lily, cassia seed, Poria cocos, the root of kudzu vine, spina date seed, ginseng, mulberries, red date, Sessileflower Acanthopanax Bark, lotus seeds, arillus longan, marine alga, natto wherein two or more or all mix, adopt biological enzymolysis or prehydrolysis SBE to extract and microencapsulation, the mixture after spray-dried and cryodesiccated extract.
2, multiple probio: make probio arrive enteron aisle by most of strong acid environment by stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote micro-absorption, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body field planting drag or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, can obviously reduce the level of intestinal endotoxemia the generation of preventing liver injury; It is also the important measures of adjusting intestinal microecology that selective enteron aisle decontamination is dyed, and has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by suppressing urease-producing in enteron aisle and producing the growth of ammonium bacteria, builds up resistance;
Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, wherein Bifidobacterium: refer to wherein a kind of, several or all mixing of bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus be a kind of, several or all mixing wherein.
3, small peptide: be oligopeptide, refer to the small molecule protein that utilizes bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need through digestion and directly absorb, bioavailability is high, in absorption and utilization, be better than free amino acid and complete protein, can be applicable in Protein intake food, especially for the low crowd of abilities of digestive and absorption, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function that improves small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,
Small peptide of the present invention refers to wherein a kind of, several or all mixing of marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.
4, prebiotics: to urge the field planting of probio enteron aisle, enteron aisle convergence, to reduce enteron aisle pH environment, also do not utilized by most enteron aisle spoilage organisms, but can promote beneficial bacteria---the growth and breeding of lactobacillus, Bifidobacterium in human body, thereby can suppress spoilage organisms growth, contribute to improve and maintain enteron aisle normal function; Long-term edible can delay senility, defaecation, raising immunity, alleviate burden of liver, improve the absorptivity of nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, pH value in colon is reduced, the growth of inhibition harmful intestinal tract bacterium; Make Water-Electrolyte in small intestine be trapped in enteric cavity, produce the high effect of oozing, stimulate enterocinesia to cause laxative, thereby promote the discharge of intestinal endotoxin and other toxicants, lactulose also directly endotoxin in deactivation enteron aisle, reduce enteron aisle pH value, extensively model is applied to the treatment of enhancing child resistant;
Prebiotics of the present invention is 2 classes
A. external source probio is had to very strong field planting effect prebiotics: the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast several or all mixing wherein;
B. common prebiotics: oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one, several or all mixing wherein;
Originally refer to one, several or all mixing wherein of oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide.
5, carbohydrate: carbohydrate is by carbon, three kinds of element compositions of hydrogen and oxygen, it be for human body provide three kinds of heat energy main nutrient in the most cheap nutrient, while taking in abundance, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA conveying hereditary information (DNA), and the glycogen containing in carbohydrate, in the time that it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms,
Carbohydrate of the present invention refers to one, several or all mixing wherein of Arabinose, glucose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen.
6. amino acid: being divided into essential amino acid and nonessential amino acid, is the base unit that forms protein, gives protein specific molecular morphosis, makes it have biochemical activity; Absorbing appropriate methionine contributes to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and the effect of playing removing toxic substances; Leucine can be repaired muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress the growth of cancer knurl, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to the ammonia in blood change urea into and excrete out; For hyperammonemia, liver dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses alimentary canal nervous by vegetative nerve and that cause and festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improves sleep and regulates mood;
Amino acid of the present invention refers to one, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.
7. vitamin and mineral matter:
Vitamin and mineral matter are the nutrients of needed by human, and the vitamin adding in the present invention is that vitamin and mineral matter are the nutrients of needed by human;
The vitamin adding in the present invention is one, several or all mixing wherein of vitamin A, vitamin D, vitamin E, vitamin K, phytomenadione, vitamin C, vitamin B1, vitamin B2, pyridoxamine, cobalamin, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin;
The mineral matter adding in the present invention is one, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;
In the present invention, the addition of vitamin and minerals is with reference to GB14880 " food enrichment use sanitary standard ", GB2760 " food additives use standard " carries out, now taking 1000g finished product as example, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.
8. the present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, extract with through biological enzymolysis or prehydrolysis SBE technology again and microencapsulation Chinese medical extract after treatment mixes, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and arrive in enteron aisle and stop field planting by gastric juice smoothly by oral, make product strengthen anti-heart disease effect and significantly improve compared with the like product of market.
9. adopt above-mentioned integrated innovation technique various batchings to be mixed to solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets " the good production specification of special medicine purposes formula food " requirement.
This characteristic of full nutrient formulation food and the effect of body is mainly manifested in to the following aspects of filling a prescription:
1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with cardiac's constitutive character, the achievement in research developments such as advanced physiology, medicine, nutrition and the clinical practice of comprehensive nowadays American Harvard University, vary with each individual, gold compatibility.
2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", adopting the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, taking prebiotics, carbohydrate, amino acid, multivitamin and mineral matter as auxiliary material, the organic assembling of various batchings, various functions are merged, and by the synergy between active ingredient, humidification effect.
3. have efficient absorption, utilize formula of the present invention, various components adopt the food of suitable ratio collocation preparation, the state that oozes such as after a certain amount of water-soluble solution, be, can arrive small intestine by stomach fast, absorption fast, completely, can supplement rapidly cardiac's desired nutritional.
4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicines, contain several functions active component, not only improve the concentration of function factor, reduce the absorption of various impurity, contribute to alleviate liver kidney burden, there is the effect that strengthens resistance of human body, the effect that has in addition promoting blood circulation, clears away heart-fire and be amusing, nourish vigour, hemangiectasis, step-down, improve microcirculation and enhancing hematopoiesis function.
5. contained probio in the present invention's formula, multiple probio can be safeguarded enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and the absorption of raising body to calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve the tolerance of host to radioactive ray, lactobacillus significantly increases intestinal mucosa immunoglobulin A (SIgA) content, body intestinal mucosa local immunity is had to regulating action, regulate stomach, the micro-ecology of intestines, can improve calcium, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, can also reduce the absorption of cholesterol.
6. formula food of the present invention is taking the food source inhibition biological active small peptide in multiple source as nitrogenous source, because small peptide does not need digestion to absorb, more be conducive to the utilization of body, can effectively improve cardiac's negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, the absorbability of raising intestinal mucosa.
7. this prescription adopts Liao Ben team by the achievement of the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence that combines prebiotics can be played the key element such as the reduction of field planting effect, enteron aisle pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula has strengthened the field planting effect to external source probio greatly.
8. contained prebiotics in the present invention's formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; form one protective barrier on intestinal mucosa surface simultaneously; can resist the damage of enteron aisle spoilage organisms to intestinal mucosa; reduce the absorption of intestinal toxic material; can also promote intestines peristalsis; accelerate the discharge of residuals in intestines; can prevent constipation; and also can strengthen immunity of organisms by the growth and breeding that promotes beneficial bacteria of intestinal tract, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.
9, in the present invention formula contained carbohydrate be for human body provide three kinds of heat energy main nutrient, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA conveying hereditary information (DNA), and the glycogen containing in carbohydrate, in the time that it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms.
10, contained amino acid in the present invention's formula, it is the base unit that forms protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and play the effect of removing toxic substances, can repair muscle, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.
11, formula food of the present invention containing multivitamin and mineral matter, can supplement rapidly the required micronutrient of cardiac, small peptide by with the chelating of calcium, iron, zinc etc. after, more increased the absorptivity of mineral matter element.
12, not fatty and cholesterol in the present invention's formula, can, in supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, has avoided the adverse effect of the high protein diet such as meat, egg.
Detailed description of the invention
Below by following examples, the invention will be further described, and it will contribute to understand the present invention.
Embodiment mono-
Realizing the full nutrient formulation food of the object of the invention heart disease is with the constitutive character in conjunction with cardiac, according to the marrow theory of Traditional Chinese Medicine, vary with each individual, gold compatibility is taking the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide as primary raw material, the food of making as auxiliary material taking prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;
Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: Radix Astragali 13g, ginkgo 13g, Ligusticum wallichii 13g, Radix Codonopsis 12g, Radix Angelicae Sinensis 12g, fruit of Chinese magnoliavine 12g, the root of straight ladybell 12g, stem of noble dendrobium 12g, Cordyceps sinensis (aweto mycelium) 11g, lucidum spore powder (broken wall) 11g, glossy ganoderma 11g, Cordyceps militaris 11g, matrimony vine 10g, Gorgon fruit 10g, lily 9g, cassia seed 5g, Poria cocos 5g, root of kudzu vine 4g, spina date seed 4g, ginseng 3g, mulberries 3g, red date 3g, Sessileflower Acanthopanax Bark 3g, lotus seeds 3g, arillus longan 2g, marine alga 2g, natto 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
First will be to be the Radix Astragali when making, ginkgo, Ligusticum wallichii, Radix Codonopsis, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, the root of straight ladybell, the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), glossy ganoderma, Cordyceps militaris, matrimony vine, Gorgon fruit, lily, cassia seed, Poria cocos, the root of kudzu vine, spina date seed, ginseng, mulberries, red date, Sessileflower Acanthopanax Bark, arillus longan, marine alga, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, Gorgon fruit adds cycloheptaamylose after soaking, after extracting by prehydrolysis SBE technology, spray-dried and preparation flour, add again the small peptide that biological enzymolysis extracts, prebiotics, amino acid, lotus seeds, natto, carbohydrate, lucidum spore powder (broken wall), after being pulverized and mixed together, multivitamin and mineral matter carry out pasteurization 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets " the good production specification of special medicine purposes formula food " requirement.
Embodiment bis-
The full nutrient formulation food of above-mentioned heart disease also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 11g, matrimony vine 20g, Gorgon fruit 18g, lily 17g, cassia seed 15g, Poria cocos 15g, root of kudzu vine 14g, spina date seed 13g, ginseng 13g, mulberries 12g, red date 12g, Sessileflower Acanthopanax Bark 11g, lotus seeds 10g, arillus longan 10g, marine alga 7g, natto 5g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g
Embodiment tri-
The full nutrient formulation food of above-mentioned heart disease also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 11g, matrimony vine 20g, Gorgon fruit 18g, lily 17g, cassia seed 15g, Poria cocos 15g, root of kudzu vine 14g, spina date seed 13g, ginseng 13g, mulberries 12g, red date 12g, Sessileflower Acanthopanax Bark 11g, lotus seeds 10g, arillus longan 10g, marine alga 7g, natto 5g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, carbohydrate 150g, prebiotics 100g, several amino acids 100g.
The present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, extract with through biological enzymolysis or prehydrolysis SBE technology again and microencapsulation Chinese medical extract after treatment mixes, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and arrive in enteron aisle and stop field planting by gastric juice smoothly by oral, make product improve heart efficacy of immunity and significantly improve compared with the like product of market.
Claims (9)
1. the full nutrient formulation food of heart disease, it is characterized in that with the constitutive character in conjunction with cardiac, according to the marrow theory of Traditional Chinese Medicine, vary with each individual, gold compatibility is taking the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide as primary raw material, the food of making as auxiliary material taking prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;
Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: Radix Astragali 13g, ginkgo 13g, Ligusticum wallichii 13g, Radix Codonopsis 12g, Radix Angelicae Sinensis 12g, fruit of Chinese magnoliavine 12g, the root of straight ladybell 12g, stem of noble dendrobium 12g, Cordyceps sinensis (aweto mycelium) 11g, lucidum spore powder (broken wall) 11g, glossy ganoderma 11g, Cordyceps militaris 11g, matrimony vine 10g, Gorgon fruit 10g, lily 9g, cassia seed 5g, Poria cocos 5g, root of kudzu vine 4g, spina date seed 4g, ginseng 3g, mulberries 3g, red date 3g, Sessileflower Acanthopanax Bark 3g, lotus seeds 3g, arillus longan 2g, marine alga 2g, natto 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
Its preparation method is for first will be to be the Radix Astragali, ginkgo, Ligusticum wallichii, Radix Codonopsis, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, the root of straight ladybell, the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), glossy ganoderma, Cordyceps militaris, matrimony vine, Gorgon fruit, lily, cassia seed, Poria cocos, the root of kudzu vine, spina date seed, ginseng, mulberries, red date, Sessileflower Acanthopanax Bark, lotus seeds, arillus longan, marine alga, natto, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, Gorgon fruit adds cycloheptaamylose after soaking, after extracting by prehydrolysis SBE technology, and the spray-dried and flour of preparation, then add the small peptide that biological enzymolysis extracts, prebiotics, amino acid, lotus seeds, natto, carbohydrate, lucidum spore powder (broken wall), multivitamin and mineral matter carry out pasteurization 1 hour after mixing, and then add the Bifidobacterium after microencapsulation, lactobacillus, the various batchings that streptococcus thermophilus also adds appropriate carbohydrate mixing again mix the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets " the good production specification of special medicine purposes formula food " requirement.
2. the full nutrient formulation food formula of heart disease according to claim 1, is characterized in that described medicine-food two-purpose Chinese herbal medicine extract is: the Radix Astragali, ginkgo, Ligusticum wallichii, Radix Codonopsis, Radix Angelicae Sinensis, the fruit of Chinese magnoliavine, the root of straight ladybell, the stem of noble dendrobium, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), glossy ganoderma, Cordyceps militaris, matrimony vine, Gorgon fruit, lily, cassia seed, Poria cocos, the root of kudzu vine, spina date seed, ginseng, mulberries, red date, Sessileflower Acanthopanax Bark, lotus seeds, arillus longan, marine alga, natto wherein two or more or all mix.
3. the full nutrient formulation food formula of heart disease according to claim 1, is characterised in that according to described formula and mixes and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food.
4. the full nutrient formulation food formula of heart disease according to claim 1, is characterized in that described prebiotics is. to external source probio, to have very strong field planting effect prebiotics be wherein several of extract, stachyose, yeast and common prebiotics of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke or all mix.
5. require the full nutrient formulation food formula of heart disease described in 1, it is characterized in that described amino acid is one, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.
6. the full nutrient formulation food formula of heart disease according to claim 1, is characterized in that described carbohydrate is one, several or all mixing wherein of Arabinose, glucose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen.
7. the full nutrient formulation food formula of heart disease according to claim 1, is characterized in that being dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, extract with through biological enzymolysis or prehydrolysis SBE technology again and microencapsulation Chinese medical extract after treatment mixes, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and arrive in enteron aisle and stop field planting by gastric juice smoothly by oral, make product prevent and treat heart disease effect and significantly improve compared with the like product of market.
8. the full nutrient formulation food formula of heart disease according to claim 1, is characterized in that described vitamin is one, several or all mixing wherein of vitamin A, vitamin D, vitamin E, vitamin K, phytomenadione, vitamin C, vitamin B1, vitamin B2, pyridoxamine, cobalamin, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin; Described mineral matter is one, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum.
9. the full nutrient formulation food formula of heart disease according to claim 1, is characterized in that described small peptide is wherein a kind of, several or all mixing of marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410402257.XA CN104187741A (en) | 2014-08-15 | 2014-08-15 | Total nutrient formula food for heart disease |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410402257.XA CN104187741A (en) | 2014-08-15 | 2014-08-15 | Total nutrient formula food for heart disease |
Publications (1)
Publication Number | Publication Date |
---|---|
CN104187741A true CN104187741A (en) | 2014-12-10 |
Family
ID=52073256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410402257.XA Pending CN104187741A (en) | 2014-08-15 | 2014-08-15 | Total nutrient formula food for heart disease |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104187741A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107252089A (en) * | 2017-04-05 | 2017-10-17 | 吉林省润生特膳食品科技开发有限公司 | A kind of hawthorn peach kernel yam flour and preparation method thereof |
CN107648512A (en) * | 2017-09-25 | 2018-02-02 | 冯静 | A kind of Chinese medicine composition and preparation method for improving microcirculation in human body |
CN107841473A (en) * | 2017-11-15 | 2018-03-27 | 江苏大学 | A kind of bacillus subtilis of high-yield nattokinase and its application |
CN112915208A (en) * | 2019-12-06 | 2021-06-08 | 倪健伟 | Composition with function of perfecting diversity of personalized intestinal flora and application thereof |
-
2014
- 2014-08-15 CN CN201410402257.XA patent/CN104187741A/en active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107252089A (en) * | 2017-04-05 | 2017-10-17 | 吉林省润生特膳食品科技开发有限公司 | A kind of hawthorn peach kernel yam flour and preparation method thereof |
CN107648512A (en) * | 2017-09-25 | 2018-02-02 | 冯静 | A kind of Chinese medicine composition and preparation method for improving microcirculation in human body |
CN107841473A (en) * | 2017-11-15 | 2018-03-27 | 江苏大学 | A kind of bacillus subtilis of high-yield nattokinase and its application |
CN112915208A (en) * | 2019-12-06 | 2021-06-08 | 倪健伟 | Composition with function of perfecting diversity of personalized intestinal flora and application thereof |
EP4070819A4 (en) * | 2019-12-06 | 2023-01-25 | Nii, Keni | Composition having wholesome personalized intestinal flora diversity function and application |
JP2023504493A (en) * | 2019-12-06 | 2023-02-03 | 健偉 倪 | Composition and use having the function of adjusting the diversity of individualized intestinal microflora |
CN112915208B (en) * | 2019-12-06 | 2023-03-21 | 倪健伟 | Composition with function of perfecting diversity of personalized intestinal flora and application thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104172191A (en) | Total-nutrition formula food for treating atherosclerosis | |
CN104187645A (en) | Anti-aging full-nutrition formula food | |
CN104839661A (en) | High uric acid formula food | |
CN104187632A (en) | Total-nutrient formulated food eaten by patients with osteoporosis | |
CN104839669A (en) | Medical formula food for anti-aging | |
CN104187636A (en) | Full-nutrition formula food suitable for people with qi-insufficiency constitution | |
CN104187634A (en) | Total nutrient formula food for sarcopenia | |
CN104839656A (en) | Liver disease medicine formula food | |
CN105029393A (en) | Medical formula food for children | |
CN104187651A (en) | High-uric-acid prevention total-nutrition formula food | |
CN104146254B (en) | The full nutritional formulas of hypertension | |
CN104187641A (en) | Total nutrient formula food for phlegm-dampness constitution | |
CN104839679A (en) | Medical formula food for people with heart disease | |
CN104996992A (en) | Medical formula food for muscle attenuation syndromes | |
CN104839659A (en) | Qi deficiency constitution medical formula food | |
CN104839672A (en) | Medical formula food for people with constitution of qi stagnation | |
CN104839684A (en) | Medical formula food for people with helicobacter pylori related gastritis | |
CN104839655A (en) | High blood lipids, blood sugar and blood pressure lowering and yang tonifying medical formula food | |
CN105029400A (en) | Medical formula food for rheumatoid arthritis | |
CN104187741A (en) | Total nutrient formula food for heart disease | |
CN105029403A (en) | Medical formula food for phlegm-damp body characters | |
CN104187721A (en) | Total nutrient formula food for cardiovascular diseases | |
CN104161266A (en) | Total nutrient formula food for patients with deficiency cold of spleen and stomach | |
CN104256656A (en) | Full-nutrition formulated food for fatty acid metabolic disorder | |
CN104839657A (en) | Medical formula food for phthisis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C53 | Correction of patent of invention or patent application | ||
CB02 | Change of applicant information |
Address after: 315000 Ningbo province high tech Zone Lingyun Road, No. 89, No. Applicant after: Hu Anran Address before: 211316 Gaochun Economic Development Zone in Jiangsu Province, the ancient road, CMC CMC, room 1, No. 316, room Applicant before: Hu Anran |
|
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20141210 |