WO2015003309A1 - 一种促进乌发的中药制剂及其制备方法 - Google Patents
一种促进乌发的中药制剂及其制备方法 Download PDFInfo
- Publication number
- WO2015003309A1 WO2015003309A1 PCT/CN2013/079038 CN2013079038W WO2015003309A1 WO 2015003309 A1 WO2015003309 A1 WO 2015003309A1 CN 2013079038 W CN2013079038 W CN 2013079038W WO 2015003309 A1 WO2015003309 A1 WO 2015003309A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sesame
- white
- black
- leaves
- celery
- Prior art date
Links
- 210000004209 hair Anatomy 0.000 title claims abstract description 56
- 239000003814 drug Substances 0.000 title claims abstract description 41
- 238000002360 preparation method Methods 0.000 title claims abstract description 36
- 230000001737 promoting effect Effects 0.000 title claims abstract description 10
- 235000003434 Sesamum indicum Nutrition 0.000 claims abstract description 47
- 240000005979 Hordeum vulgare Species 0.000 claims abstract description 26
- 235000007340 Hordeum vulgare Nutrition 0.000 claims abstract description 26
- 240000007087 Apium graveolens Species 0.000 claims abstract description 24
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 claims abstract description 24
- 235000010591 Appio Nutrition 0.000 claims abstract description 24
- 235000019483 Peanut oil Nutrition 0.000 claims abstract description 23
- 244000235659 Rubus idaeus Species 0.000 claims abstract description 23
- 210000000941 bile Anatomy 0.000 claims abstract description 23
- 239000000312 peanut oil Substances 0.000 claims abstract description 23
- 235000009122 Rubus idaeus Nutrition 0.000 claims abstract description 20
- 235000011034 Rubus glaucus Nutrition 0.000 claims abstract description 19
- 244000000231 Sesamum indicum Species 0.000 claims abstract description 11
- 239000000203 mixture Substances 0.000 claims abstract description 11
- 238000003756 stirring Methods 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims abstract description 3
- 235000013912 Ceratonia siliqua Nutrition 0.000 claims abstract 7
- 240000008886 Ceratonia siliqua Species 0.000 claims abstract 7
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims abstract 5
- 241001521901 Tribulus lanuginosus Species 0.000 claims abstract 3
- 241000207961 Sesamum Species 0.000 claims description 36
- 240000000249 Morus alba Species 0.000 claims description 25
- 235000008708 Morus alba Nutrition 0.000 claims description 25
- 244000020518 Carthamus tinctorius Species 0.000 claims description 19
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims description 19
- 235000020097 white wine Nutrition 0.000 claims description 16
- 241000208966 Polygala Species 0.000 claims description 12
- 239000003921 oil Substances 0.000 claims description 11
- 235000019198 oils Nutrition 0.000 claims description 11
- 240000003243 Thuja occidentalis Species 0.000 claims description 10
- 235000008109 Thuja occidentalis Nutrition 0.000 claims description 10
- 240000002924 Platycladus orientalis Species 0.000 claims description 9
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 6
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- 239000000919 ceramic Substances 0.000 claims description 3
- 229910052742 iron Inorganic materials 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 235000000177 Indigofera tinctoria Nutrition 0.000 claims description 2
- 229940097275 indigo Drugs 0.000 claims description 2
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 claims description 2
- 235000021013 raspberries Nutrition 0.000 claims description 2
- 235000013813 Gleditsia triacanthos Nutrition 0.000 claims 5
- 240000001549 Ipomoea eriocarpa Species 0.000 claims 5
- 235000005146 Ipomoea eriocarpa Nutrition 0.000 claims 5
- MUKYLHIZBOASDM-UHFFFAOYSA-N 2-[carbamimidoyl(methyl)amino]acetic acid 2,3,4,5,6-pentahydroxyhexanoic acid Chemical compound NC(=N)N(C)CC(O)=O.OCC(O)C(O)C(O)C(O)C(O)=O MUKYLHIZBOASDM-UHFFFAOYSA-N 0.000 claims 4
- 241000533849 Gleditsia Species 0.000 claims 4
- 241000819233 Tribulus <sea snail> Species 0.000 claims 4
- 229940047183 tribulus Drugs 0.000 claims 4
- 244000105624 Arachis hypogaea Species 0.000 claims 3
- 235000020232 peanut Nutrition 0.000 claims 3
- 244000230012 Gleditsia triacanthos Species 0.000 claims 1
- 241000736211 Platycladus Species 0.000 claims 1
- 244000144725 Amygdalus communis Species 0.000 abstract description 7
- 235000011437 Amygdalus communis Nutrition 0.000 abstract description 7
- 241001080798 Polygala tenuifolia Species 0.000 abstract description 7
- 235000020224 almond Nutrition 0.000 abstract description 7
- 241000931143 Gleditsia sinensis Species 0.000 abstract 1
- 235000015096 spirit Nutrition 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 30
- 235000010643 Leucaena leucocephala Nutrition 0.000 description 16
- 240000007472 Leucaena leucocephala Species 0.000 description 12
- 241000219977 Vigna Species 0.000 description 11
- 235000010726 Vigna sinensis Nutrition 0.000 description 11
- 235000015278 beef Nutrition 0.000 description 10
- 229940079593 drug Drugs 0.000 description 10
- 210000004185 liver Anatomy 0.000 description 10
- 241000283690 Bos taurus Species 0.000 description 9
- 244000236658 Paeonia lactiflora Species 0.000 description 8
- 235000008598 Paeonia lactiflora Nutrition 0.000 description 8
- 241000196324 Embryophyta Species 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 206010011224 Cough Diseases 0.000 description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 description 5
- 244000046052 Phaseolus vulgaris Species 0.000 description 5
- 208000026435 phlegm Diseases 0.000 description 5
- 210000004761 scalp Anatomy 0.000 description 5
- 210000003491 skin Anatomy 0.000 description 5
- 239000010017 yuan zhi Substances 0.000 description 5
- 241000220479 Acacia Species 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 4
- 235000019197 fats Nutrition 0.000 description 4
- 210000003780 hair follicle Anatomy 0.000 description 4
- 230000003779 hair growth Effects 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 239000002453 shampoo Substances 0.000 description 4
- 201000004384 Alopecia Diseases 0.000 description 3
- 241000272199 Ciconia ciconia Species 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 208000006673 asthma Diseases 0.000 description 3
- 235000019658 bitter taste Nutrition 0.000 description 3
- 230000001914 calming effect Effects 0.000 description 3
- 230000036461 convulsion Effects 0.000 description 3
- 208000024963 hair loss Diseases 0.000 description 3
- 230000003676 hair loss Effects 0.000 description 3
- 210000003128 head Anatomy 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 239000008141 laxative Substances 0.000 description 3
- 230000002475 laxative effect Effects 0.000 description 3
- 230000003340 mental effect Effects 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- -1 oleic acid 41.2% Chemical class 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 3
- 229930182490 saponin Natural products 0.000 description 3
- 150000007949 saponins Chemical class 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 235000019640 taste Nutrition 0.000 description 3
- 235000019156 vitamin B Nutrition 0.000 description 3
- 239000011720 vitamin B Substances 0.000 description 3
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 244000004281 Eucalyptus maculata Species 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 241000238631 Hexapoda Species 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 240000004343 Indigofera suffruticosa Species 0.000 description 2
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 2
- 239000005642 Oleic acid Substances 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 2
- 241000239226 Scorpiones Species 0.000 description 2
- 102000003425 Tyrosinase Human genes 0.000 description 2
- 108060008724 Tyrosinase Proteins 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 208000030961 allergic reaction Diseases 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000036506 anxiety Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 239000010685 fatty oil Substances 0.000 description 2
- 229930003935 flavonoid Natural products 0.000 description 2
- 150000002215 flavonoids Chemical class 0.000 description 2
- 235000017173 flavonoids Nutrition 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- VKOBVWXKNCXXDE-UHFFFAOYSA-N icosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCC(O)=O VKOBVWXKNCXXDE-UHFFFAOYSA-N 0.000 description 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 2
- 230000000366 juvenile effect Effects 0.000 description 2
- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- 235000020778 linoleic acid Nutrition 0.000 description 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 229910052573 porcelain Inorganic materials 0.000 description 2
- 230000001568 sexual effect Effects 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 230000002087 whitening effect Effects 0.000 description 2
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 244000141006 Armeniaca sibirica Species 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 206010006312 Breast swelling Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 241001391944 Commicarpus scandens Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- UBSCDKPKWHYZNX-UHFFFAOYSA-N Demethoxycapillarisin Natural products C1=CC(O)=CC=C1OC1=CC(=O)C2=C(O)C=C(O)C=C2O1 UBSCDKPKWHYZNX-UHFFFAOYSA-N 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 241000282807 Diceros bicornis Species 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 208000017701 Endocrine disease Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241000402754 Erythranthe moschata Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 208000001034 Frostbite Diseases 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 108010007979 Glycocholic Acid Proteins 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 241000765857 Gyna Species 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010019705 Hepatic pain Diseases 0.000 description 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 1
- RFDAIACWWDREDC-UHFFFAOYSA-N Na salt-Glycocholic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCC(O)=O)C)C1(C)C(O)C2 RFDAIACWWDREDC-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 241000816490 Physostegia parviflora Species 0.000 description 1
- 240000000432 Pistacia chinensis Species 0.000 description 1
- 206010063493 Premature ageing Diseases 0.000 description 1
- 208000032038 Premature aging Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
- 241001092459 Rubus Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- WBWWGRHZICKQGZ-UHFFFAOYSA-N Taurocholic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCCS(O)(=O)=O)C)C1(C)C(O)C2 WBWWGRHZICKQGZ-UHFFFAOYSA-N 0.000 description 1
- 241001533104 Tribulus terrestris Species 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 229940025131 amylases Drugs 0.000 description 1
- 230000001760 anti-analgesic effect Effects 0.000 description 1
- 108010051210 beta-Fructofuranosidase Proteins 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229910052797 bismuth Inorganic materials 0.000 description 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 description 1
- 230000003925 brain function Effects 0.000 description 1
- 235000005473 carotenes Nutrition 0.000 description 1
- 150000001746 carotenes Chemical class 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 208000017580 chronic wasting disease Diseases 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- RFDAIACWWDREDC-FRVQLJSFSA-N glycocholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 RFDAIACWWDREDC-FRVQLJSFSA-N 0.000 description 1
- 229940099347 glycocholic acid Drugs 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000003648 hair appearance Effects 0.000 description 1
- 239000003676 hair preparation Substances 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000004377 improving vision Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 235000011073 invertase Nutrition 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 150000002515 isoflavone derivatives Chemical class 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 235000008777 kaempferol Nutrition 0.000 description 1
- 235000021332 kidney beans Nutrition 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
- 235000019626 lipase activity Nutrition 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 206010027175 memory impairment Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- UXOUKMQIEVGVLY-UHFFFAOYSA-N morin Natural products OC1=CC(O)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 UXOUKMQIEVGVLY-UHFFFAOYSA-N 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000018343 nutrient deficiency Nutrition 0.000 description 1
- 208000030212 nutrition disease Diseases 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000010341 ping gan Substances 0.000 description 1
- 239000003495 polar organic solvent Substances 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 206010039766 scrub typhus Diseases 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 230000002522 swelling effect Effects 0.000 description 1
- WBWWGRHZICKQGZ-GIHLXUJPSA-N taurocholic acid Chemical compound C([C@@H]1C[C@H]2O)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]2(C)[C@H](O)C1 WBWWGRHZICKQGZ-GIHLXUJPSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/413—Gall bladder; Bile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/10—Preparations for permanently dyeing the hair
Definitions
- the invention relates to a traditional Chinese medicine preparation for promoting the action of black hair, in particular to a traditional Chinese medicine preparation and a preparation method relating to the effect of the black hair. Background technique
- the object of the present invention is to provide a traditional Chinese medicine preparation for promoting the effect of black hair on the basis of the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and in particular, a preparation and preparation method for providing such a black hair effect,
- the prepared preparation can be applied to each The scalp is characterized by no allergic reaction after washing the hair, no toxic and side effects, so that the medicine can quickly penetrate into the skin, achieve the purpose of UFA, and the cost is low, and the preparation process is simple and easy.
- the preparation of the invention is made up of peanut oil, white wine, black cow bile, sesame flower, sesame stem, buffalo, cowpea, white peony, barley, oriental arborvitae, mulberry leaf, safflower, polygala, acacia, covering
- the mass ratio of each component is:
- Peanut oil 1200-1600g white wine 100-180g black beef bile 40_60g sesame flower 20-40g sesame stem 60-80g : beef 20-30g cowpea 40- 60g white peony 20-30g ⁇ 20-30g
- Leaf 20- 30g Mulberry 20-30g Safflower 30-40g Polygala 30-40g Acacia 20-30g Raspberry 30-40g
- the preferred raw material quality ratio of the present invention is: peanut oil 1400-1600g white wine 160-180g black cattle bile 50_60g sesame flower 30-40g sesame stem 70-80g: beef 20-25g cowpea 30-60g chalk 25-30g ⁇ 25-30g
- the present invention can also preferably optimize the quality of raw materials.
- the preparation method of the above-mentioned UFA traditional Chinese medicine preparation comprises the following steps:
- sesame flower, sesame stem, gynosoris, cowpea, white peony, barley, arborvitae, mulberry leaves are proportioned, crushed by a pulverizer and passed through a 80 mesh sieve, then at 50-70 ° C Dry at high temperature, then naturally dry to room temperature for use;
- the celery juice is stirred for five minutes and then allowed to stand for at least one night to form a paste.
- safflower, polygala, acacia, raspberry, ., barley is proportioned, crushed by a pulverizer and passed through a 80 mesh sieve, and then dried at a high temperature of 50-70 ° C, and then In the future, fry for half an hour, and let stand to room temperature, then add white wine, stir for 10 minutes, and finally put it in a porcelain jar and serve.
- the prepared cream preparation is used to wipe the scalp alone or to clean the hair. If it is mixed into a common shampoo, the effect will be better.
- the theoretical basis of the invention is: peanut oil, light yellow transparent, clear color, fragrant smell, delicious taste, is an edible oil that is easier to digest.
- Peanut oil contains more than 80% of unsaturated fatty acids (including oleic acid 41.2%, linoleic acid 37.6%). It also contains 19.9% of saturated fatty acids such as palmitic acid, stearic acid and arachidic acid.
- the fatty acid composition of peanut oil is better, and it is easy for human body to digest and absorb. Choline in peanut oil can also improve the memory of the human brain and delay the decline of brain function.
- Black cow bile which has a very high similarity to the bile of the human body, belongs to the homologous digestive juice, and the bovine bile contains 10% ⁇ 15% of the bile, which is mainly the sodium salt of taurocholic acid and glycocholic acid; In addition, it also contains other ingredients such as bilirubin and egg pity.
- bovine bile has the functions of enhancing lipase activity and promoting the absorption of fatty acids and fat-soluble vitamins (vitamin A, D, E, K). At the same time, it can spleen and dampness and phlegm.
- Sesame flower scientific name Physostegiavirginiana, sesame flower harvested flowers in summer, used for drying.
- the seeds contain fatty oil, which can lower blood sugar, increase the glycogen content in the liver and muscle, and have a diarrhea effect.
- Sesame flowers are flat and sweet. It has hair growth and swelling effect. Can be used to treat hair loss, white hair, frostbite, constipation.
- Kidney beans also known as horns, are the seeds of an ornamental tree in China and Japan. Legumes are favored by people in foods, and cowpeas have been used by diet experts and scholars for their rich connotations. Concerned, and listed as top grade, has the reputation of "bean aristocrats.” It contains flavonoids and isoflavones, scorpion scorpion, scorpion scorpion, quercetin, kaempferol, musk scent, flavonoids and triterpenoids, and contains 15 kinds of amino acids. Oleic acid 22.3%, linoleic acid 53%, linolenic acid 12%, has the effect of improving vision and hair quality.
- White peony a mature fruit of the annual or perennial herb ⁇ Tribulus ter- restris L. Sexual bitterness, Xin, Ping, into the liver. It can calm the liver and relieve the phlegm. For liver and yang dizziness headache, liver depression, hypochondriac pain, wind and heat headache, red eyes and swelling, skin itching and other symptoms.
- the barley is a dry pigment in the dicotyledonous plant of the dicotyledonous plant, the horse blue, the dicotyledonous plant, the leguminous plant blue, the dicotyledonous plant, the cruciferous plant, the indigo, the grass, or the indigo plant.
- Jiangxi, Henan, Sichuan and other places are also produced.
- the quality produced in Fujian is the best, and the taste of barley is salty and cold. It can clear away heat and detoxify, cool blood and eliminate spots, clear the liver and diarrhea, and set a shock.
- Mulberry leaves are the dry leaves of the genus Sangke, also known as mulberry, mulberry, mulberry, and yellow mulberry. They are produced in most parts of the country and have the functions of lowering blood pressure, blood fat, anti-inflammatory, etc., which can evacuate wind and heat. Qingfei Runzao, calming liver and yang, clearing liver and eyesight, cooling blood to stop bleeding. China's ancient medical directory "The Record of Life Keeping Record” has been recorded in the mulberry leaves can be "retained in the face, black hair, filling the marrow, dysentery and prolonging.”
- Safflower also known as safflower. Dicotyledonous, Compositae, with a specific aroma, slightly bitter taste. It is better to use long flower, bright red color and soft texture. It can pass the blood to pass through, to relieve pain. In the present invention, it belongs to the blood circulation medicine.
- Radix Polygalae is a commonly used traditional Chinese medicine. It is regarded as a life-saving medicine in Chinese medicine. It is derived from the dry roots of Polygala tenuifolia Wi lld. and P. sibirica L.. Sexual temperature, bitter taste, Xin, with the function of soothing, phlegm and swelling, for insomnia caused by heart and kidney discomfort, dreams, forgetfulness, convulsions, convulsions, coughing, sore swollen, breast swelling Pain embolism.
- Raspberry plants can be used as medicines, which have a variety of drug values, and their fruits have the effect of tonifying kidney and strengthening yang.
- Raspberry oil is an unsaturated fatty acid that promotes the secretion of hormones from the prostate.
- Barley containing carbohydrates 63. 4%, protein 10. 2%, dietary fiber 9.9%, also contains B vitamins.
- Barley malt contains mainly two amylases and invertases. Barley also contains maltose, dextrin, B vitamins, pity, glucose, etc. Barley tastes salty, sweet, warm, cold, non-toxic. The effect of barley is to eliminate thirst and heat, and to replenish the body. Nourishing the labor, making the blood strong, good for the skin, enriching the five internal organs, digesting the grain, stopping the venting, and not moving the atmosphere. Long-term consumption can make people grow white and fat, and the skin is smooth and creamy. At the same time, barley can promote hair nutrition and make hair black and shiny.
- Celery also known as western celery, is rich in nutrients, rich in protein, carbohydrates, minerals and multivitamins. It also contains celery oil, which has the effects of lowering blood pressure, calming, stomach and diuresis. It is a kind of health care. Vegetable, in the compatibility of the traditional Chinese medicine of the invention, has the effects of calming liver and clearing heat, phlegm and dampness, and laxative. Liquor, known as the "longest of 100 medicines", is stable, safe and effective, and because alcohol is a good semi-polar organic solvent, the various active ingredients of traditional Chinese medicine are easily soluble in it. The wine helps the drug to fully exert its effectiveness and improve the therapeutic effect.
- the color of the hair depends on the number, size and distribution of pigment particles in the fur, as well as the nature of the pigment and various optical effects. Graying or whitening of the hair in old age is a physiological phenomenon associated with the gradual loss of tyrosinase activity in the hair bulb. At present, the causes of adolescents and middle-aged white hair are still not fully understood in medicine. At present, Chinese medicine believes that it is related to genetic, mental factors, endocrine disorders and nutritional deficiencies, kidney deficiency and blood heat. Juvenile white hair occurs in children and adolescents and often has a family history. Except for increased white hair, it does not affect your health. White hair suddenly occurs in youth, and some are related to nutritional disorders.
- white hair occurs due to extreme anxiety.
- juvenile white is mainly caused by a decrease in hair melanin formation, a decrease in melanin-forming function by melanocytes, and a decrease in tyrosinase activity.
- Excessive emotional stress, excessive brain use, anxiety, panic, and nerve trauma may cause white hair.
- white hair may also appear in physiological chronic wasting diseases.
- white hair can be a symptom of certain diseases, such as premature aging.
- the regulation of human body function, adjustment of human body secretion, balance the internal organs, smooth mental mood, promote blood circulation in the head, can effectively inhibit white hair, and has a good black hair effect.
- the combination of the above compositions can enhance the conditioning effect, and is rich in mineral oils such as vitamin E, vitamin B1, linoleic acid, protein, sesame, polypentose, calcium, pity, iron and the like in peanut oil.
- the combination of nutrients further regulates the body's functions, promotes blackening of the hair, brightens the hair, enhances the elasticity and luster of the hair, and makes the hair loose and easy to comb.
- Clinical Experiment 1 1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the six months from January 2013 to June 2013 are selected.
- observation object 40 cases of Shenzhen City Hospital of Guangdong province were selected: 20 males and 20 females; age: 18-25 years old, 18 cases, 25-35 years old; occupation: 10 students, workers 10 For example, 5 farmers, 10 teachers, and 5 other.
- Course of disease From the onset to the time of treatment, 20 cases in 2 years, 10 cases in 2-4 years, and 10 cases in 4 years.
- the effect criteria are divided into: Significantly, white hair turns black more than 85%; Effective, white hair turns black more than 50%, white hair is controlled; Ineffective, white hair is basically not improved and alleviated.
- the effect criteria are divided into: Significantly, white hair turns black more than 85%; Effective, white hair turns black more than 50%, white hair is controlled; Ineffective, white hair is basically not improved and alleviated.
- the preparation prepared by the invention can be applied to hair and scalp of various characteristics, and has no allergic reaction after washing the hair, has no toxic and side effects, and makes the drug It can quickly penetrate into the skin to achieve the purpose of Ufa, and it has quick effect, good hair growth effect, low cost and easy preparation process.
- the preparation of the invention is made up of peanut oil, white wine, black cow bile, sesame flower, sesame stem, gyna, cowpea, white peony, barley, oriental arborvitae, mulberry leaf, safflower, polygala, acacia, raspberry, almond, barley a paste preparation of a composition prepared from celery,
- the mass ratio of each component is:
- Peanut oil 1200g white wine 100g black beef bile 40g
- Yuanzhi 30g acacia 20g raspberry 30g
- the preparation method of the above-mentioned UFA traditional Chinese medicine preparation comprises the following steps:
- sesame flower, sesame stem, gynosoris, cowpea, white peony, barley, arborvitae, mulberry leaves are proportioned, crushed by a pulverizer and passed through a 80 mesh sieve, then at 50-70 ° C Dry at high temperature, then naturally dry to room temperature for use;
- the celery juice is stirred for five minutes and then allowed to stand for at least one night to form a paste.
- safflower, polygala, acacia, raspberry, ., barley are proportioned, crushed by a pulverizer and passed through a 80 mesh sieve, and then dried at a high temperature of 50-70 ° C, and then
- the above paste preparations are stirred once a day, morning and evening, 10 minutes each time, after three days, slightly fry for half an hour, and then allowed to stand at room temperature, then add white wine, and stir for 10 minutes, and finally in the porcelain jar After that.
- the prepared cream preparation is used to wipe the scalp alone or to clean the hair. If it is mixed into a common shampoo, the effect will be better.
- the preferred raw material quality of the present invention is (g):
- Platycladus orientalis 30g mulberry leaves 30g safflower 40g
- Yuanzhi 40g acacia 30g raspberry 40g
- the preparation method is as in Example 1.
- the mass of each component is (g):
- Platycladus orientalis 30g mulberry leaves 20g safflower 40g
- the preparation method is as in Example 1.
- the mass of each component is (g): Peanut oil 1300g white wine 120g black beef bile 50g sesame flower 25g sesame stem 65g ⁇ 25g
- the preparation method is as in Example 1.
- the above embodiments are only a few of the various embodiments of the present invention, such as increasing or decreasing the dosage of each formulation according to the technical solution, the therapeutic effect of the prepared hair preparation is not affected, and will also fall on It is within the scope of the claims of the present invention.
Abstract
一种促进乌发的中药制剂及其制备方法,该制剂是由花生油、白酒、黑牛胆汁、芝麻花、芝麻梗、牵牛子、槐豆、白蒺藜、青黛、侧柏叶、桑叶、红花、远志、皂荚、覆盆子、杏仁、大麦、西芹经过混合、粉碎、煎煮、搅泮等工序制备成的组合物膏状制剂。
Description
一种促进乌发的中药制剂及其制备方法 技术领域
本发明涉及一种促进乌发作用的中药制剂,具体的说是涉及这种 乌发作用的中药制剂及制备方法。 背景技术
在现代都市高效率、 快节奏的工作生活中, 人们的白发、 脱发现 象日渐增多, 也越来越严重, 尤其是年轻人经常为很早就转成的白发 所苦恼, 目前市场上治疗白发的药物制剂不少, 但是对于西药来说, 一是价格比较昂贵, 持续几个疗程的治疗, 给患者增加了不小的经济 负担, 二是长时间的用药容易给身体机能带来一定的副作用; 对于市 场上的纯中药, 药效慢, 不稳定, 对头部毛囊的刺激作用虽然暂时有 一部分白发转黑, 如果一旦停止用药, 就又有白发出现, 甚至容易脱 落, 这主要和毛囊的病变和毛发生长环境缺乏营养有关, 患者需要有 一种疗效好, 使白发能转黑持久, 并且价格相对比较低廉的药物来解 决上述问题。
本发明的目的即在于针对上述不足, 在祖传秘方的基础上, 结合 现代中西医技术, 提供一种促进乌发作用的中药制剂, 具体的说提供 这种乌发作用的制剂及制备方法, 本发明制成的制剂, 可以适用于各
种特点的头皮, 用其清洗头发后无过敏反应, 无毒副作用, 使药物能 迅速渗入皮肤,达到乌发的目的,而且成本低廉、制取工艺简便易行。
本发明的技术方案如下所述:
本发明制剂是由花生油、 白酒、 黑牛胆汁、 芝麻花、 芝麻梗、 牵 牛子、 槐豆、 白蒺藜、 青黛、 侧柏叶、 桑叶、 红花、 远志、 皂荚、 覆
:、 大麦、 西芹制备成的组合物膏状制剂,
其中各组分的质量配比为:
花生油 1200-1600g 白酒 100-180g 黑牛胆汁 40_60g 芝麻花 20-40g 芝麻梗 60-80g :牛子 20-30g 槐豆 40- 60g 白蒺藜 20-30g 黛 20-30g
叶 20- 30g 桑叶 20-30g 红花 30-40g 远志 30-40g 皂荚 20-30g 覆盆子 30-40g
30— 40g 大麦 30-40g 西芹 130-140gc 为了获得更好的效果, 本发明可优选的原料质量配比为: 花生油 1400-1600g 白酒 160-180g 黑牛胆汁 50_60g 芝麻花 30-40g 芝麻梗 70-80g :牛子 20-25g 槐豆 30-60g 白蒺藜 25-30g 黛 25-30g
叶 25-30g 桑叶 25-30g 红花 35-40g 远志 35-40g 皂荚 25-30g 覆盆子 35-40g
35-40g 大麦 35-40g 西芹 135-140gc 当然, 为了获得进一步好的效果, 本发明还可优选的原料质量配
花生油 1600g 白酒 180g 黑牛胆汁 60g 芝麻花 40g 芝麻梗 75g
槐豆 40g 白蒺藜 25g
侧柏叶 25g 桑叶 25g 红花 35g
远志 35g 皂荚 30g 覆盆子 35g
35g 西芹 140g。
上述乌发中药制剂的制备方法, 包括如下步骤:
1 )、将芝麻花、 芝麻梗、 牵牛子、 槐豆、 白蒺藜、 青黛、侧柏叶、 桑叶按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的 高温下烘干, 然后自然晾到室温备用;
2 )、将花生油放到铁锅内加热至 90-120摄氏度, 然后将芝麻花、 芝麻梗、 牵牛子、 槐豆、 白蒺藜、 青黛、 侧柏叶、 桑叶的粉末, 下入 油锅内与花生油同煎, 十五分钟后取出清油备用;
3 )、将上述清油放入陶瓷罐子内盛放, 然后加入黑牛胆汁和西芹
;出的西芹汁, 一直搅拌五分钟后, 静置经过至少一夜, 形成膏状制
4)、 将红花、 远志、 皂荚、 覆盆子、 .、 大麦按比例配好, 经 过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温下烘干, 然后自
日后微火煎半小时, 并静置到室温, 然后加入白酒, 并搅拌 10分钟, 最后装于瓷罐后即成。
制取的膏状制剂单独使用擦拭头皮或清洗头发,如果将其混入到 普通的洗发液中使用, 效果会更好。 本发明的理论依据在于: 花生油, 淡黄透明, 色泽清亮, 气味芬芳, 滋味可口, 是一种比 较容易消化的食用油。 花生油含不饱和脂肪酸 80%以上 (其中含油酸 41. 2%, 亚油酸 37. 6%) 。 另外还含有软脂酸, 硬脂酸和花生酸等饱 和脂肪酸 19. 9%。 花生油的脂肪酸构成是比较好的, 易于人体消化吸 收。 花生油中的胆碱, 还可改善人脑的记忆力, 延缓脑功能衰退。
黑牛胆汁, 与人体的胆汁在结构上有极高的相似度, 属同源性消 化液, 牛胆汁含胆酸盐 10 %〜15 %, 主要为牛胆酸与甘胆酸的钠盐; 此外, 还含胆红素、 卵憐脂等其他成分。 在机体中, 牛胆汁有增强脂 肪酶活性、 促进脂肪酸与脂溶性维生素 (维生素 A、 D、 E、 K) 吸收 等作用。 同时可以健脾燥湿化痰, 定惊平喘。
芝麻花,学名 Physostegiavirginiana ,芝麻花夏季采收花朵, 晒干用。 种子含脂肪油, 可以降低血糖, 增加肝脏及肌肉中的糖 元含量, 有致泻作用。 芝麻花性平味甘, 平。 有生发, 消肿作用。 可以用于治疗脱发白发、 冻疮、 便秘。
芝麻梗, 平肝肾, 可治疗肝胃气痛, 风湿性关节炎, 在中医上和 其他中药配伍, 用于治疗脱发和促进生发。
牵牛子, 性寒, 味苦; 有毒。含牵牛子甙(树脂甙类)、 脂肪油、 有机酸等, 功能主治: 泻水通便, 消痰涤饮, 杀虫攻积。 用于水肿胀 满, 二便不通, 痰饮积聚, 气逆喘咳, 虫积腹痛, 蛔虫、 绦虫病。 具 有泻下、 利尿、 消肿、 驱虫等功效。 和本发明中其他中药配伍, 可以 促进新陈代谢, 利于头部毛囊分泌。
槐豆, 也称槐角, 中国和日本的一种观赏乔木的种子, 豆科类植 物在食品中以营养丰富而备受人们青睐,而槐豆更以其丰富的内涵被 历代饮食专家和学者所关注,并被列为上品,有 "豆中贵族"之美誉。 它含有黄酮类及异黄酮化合物、槐角甙、槐属双甙、槲皮素、 山柰酚、 芸香甙、 槐属黄酮甙及三萜类化合物质, 并含有 15种氨基酸, 槐豆 富含油酸 22. 3%、 亚油酸 53%、 亚麻酸 12%, 具有改善视力、 发质的 功效。
白蒺藜, 为蒺藜科一年生或多年生草本植物蒺藜 Tribulus ter— restris L. 的成熟果实。 性苦、 辛, 平, 入肝经。 可以平肝解 郁, 祛风明目。用于肝阳眩晕头痛, 肝郁胁痛, 风热头痛, 目赤肿痛, 皮肤瘙痒等症。
青黛为双子叶植物药爵床科植物马蓝 、 双子叶植物药豆科植物 木蓝 、 双子叶植物药十字花科植物菘蓝、 草大青或蓼科植物蓼蓝叶 中的干燥色素。 主产于福建、 云南、 江苏、 安徽等地。 此外, 江西、 河南、 四川等地亦产。 福建所产的品质最佳, 青黛性味咸寒。 可以清 热解毒, 凉血消斑, 清肝泻火, 定惊。主治: 温病热盛, 斑疹, 吐血、 咯血, 咽痛口疮, 小儿惊痫, 疮肿, 丹毒, 蛇虫咬伤等。
侧柏叶: 柏科植物侧柏 (学名: Platycladus oriental is (L. ) Franco)的嫩枝叶。药材侧柏叶多有分支, 小且长短不一, 为鳞片状。 颜色为红褐色。 表面可见叶相互对生, 断面黄白色。 质地松脆、 易被 折断。 气微香, 味苦涩, 中药上凉血止血药中的一种, 有止血、 乌须 发、 止咳喘的功效。 我国古籍 《千金翼方》 曾记载: 治发落。
桑叶, 是桑科植物皇的干燥叶, 又名家桑、 荆桑、 桑椹树、 黄桑 等, 全国大部分地区多有生产, 具有降血压、 血脂、 抗炎等作用, 可 以疏散风热, 清肺润燥, 平抑肝阳, 清肝明目, 凉血止血。 我国 古代医学名录 《保生要录》 中曾有记载, 桑叶可以 "驻容颜, 乌 须发, 补髓填精, 祛疾延年"。
红花, 又称草红花。 双子叶植物, 菊科, 具特异香气, 味微苦。 以花片长、 色鲜红、 质柔软者为佳。 可以活血通经, 去瘀止痛。 用于 本发明中, 属于活血通经药。
远志 (Radix Polygalae ) 为常用中药, 在我国中医学上被视为 养命要药, 来源于远志科植物远志 Polygala tenuifolia Wi lld. 和 卵叶远志 P. sibirica L.的干燥根。 性温, 味苦、 辛, 具有安神益智、 祛痰、 消肿的功能, 用于心肾不交引起的失眠多梦、 健忘惊悸, 神志 恍惚, 咳痰不爽, 疮疡肿毒, 乳房肿痛等症。
皂荚, 别名鸡栖子、 皂角、 大皂荚、 长皂荚、 悬刀、 长皂角、 大皂角、 乌犀。 归于肺; 大肠经, 可以祛痰止咳; 开窍通闭; 杀虫散 结。 它含皂角类成分的药物, 能够清热化湿、 祛除多余脂肪、 通畅阻 塞毛囊, 对防脱发和乌发效果颇佳, 而且不会过度刺激头皮。
覆盆子 (学名: Rubus idaeus ) 是一种蔷薇科悬钩子属的木本植 物, 覆盆子的果实是一种聚合果, 有红色, 金色和黑色, 在欧美作为 水果, 在中国大量分布但少为人知, 仅在东北地区有少量栽培, 市场 上比较少见。 覆盆子植物可入药, 有多种药物价值, 其果实有补肾壮 阳的作用。 覆盆子油属于不饱和脂肪酸, 可促进前列腺分泌激素。
杏仁, 味苦, 微温; 有小毒。 杏仁富含蛋白质、 脂肪、 糖类、 胡 萝卜素、 B族维生素、 维生素 C、 维生素 P以及钙、 憐、 铁等营养成 分, 可以止咳平喘, 润肠通便。 具有抗炎、 镇痛作用。
大麦, 含碳水化合物 63. 4%, 蛋白质 10. 2%, 膳食纤维 9. 9%, 还含 B族维生素等。大麦芽主要含两种淀粉酶,转化糖酶。大麦还含、 麦芽糖、 糊精、 B族维生素, 憐脂、 葡萄糖等, 大麦性味咸、 甘、 性 温、 寒, 无毒。 大麦的功效有消渴除热毒, 益气调中。 滋补虚劳, 使 血脉强壮, 对肤色有益, 充实五脏, 消化谷食, 止泄, 不动风气。 长 时间食用, 可使人长得又白又胖, 肌肤滑腻。 同时, 大麦可以促进头 发营养, 使头发变乌黑光亮。
西芹又名西洋芹菜, 其营养丰富, 富含蛋白质、 碳水化合物、 矿 物质及多种维生素等营养物质, 还含有芹菜油, 具有降血压、 镇静、 健胃、 利尿等疗效, 是一种保健蔬菜, 在本发明的中药配伍中, 具有 平肝清热, 祛风利湿、 通便的功效。 白酒, 素有"百药之长"之称, 白酒性质稳定、 安全有效, 而且因 为酒精是一种良好的半极性有机溶剂,中药的各种有效成分都易溶于 其中, 药借酒力、 酒助药势而充分发挥其效力, 提高治疗效果。
毛发的颜色取决于毛皮质中色素颗粒的数目、大小和分布, 以及 色素性质和各种光学效应。 老年时头发变灰或变白是一种生理现象, 与毛球中酪氨酸酶活性逐渐丧失有关。 目前, 青少年以及中年白发的原因在医学上现在还不十分清楚, 目前中医认为与遗传、 精神因素、 内分泌失调和营养缺乏、 肾虚和血 热等因素有关。少年白发发生于儿童及青少年, 常有家族史, 除白发 增多外, 不影响身体健康。 青春时期骤然发生的白发, 有的与营养障 碍有关。 同时精神因素可影响头发变白, 有报道由于就极度焦虑而发 生白发者。现代医学认为, 少年白主要是毛发黑色素形成减少, 由黑 素细胞形成黑色素的功能减弱, 酪氨酸酶的活动减低所致。凡情绪过 度紧张、用脑过度、忧虑、惊恐、神经外伤等都可能造成白发, 此外, 生理慢性消耗性疾病时也可能出现白发。同时白发可以是某些疾病的 一个症状, 如早老症等。 故此, 调节人体机能, 调整人体内分泌, 平 衡五脏六腑, 平稳精神情绪, 促进头部血液循环, 可以有效的抑制白 发, 同时具有很好的乌发效果。 上述组合物的配伍组合, 可以增强调理作用, 并与花生油中的维 生素 E、 维生素 Bl、 亚油酸、 蛋白质、 麻糖、 多缩戊糖、 钙、 憐、 铁 等矿物质和各种丰富的营养成分相结合进一步调理人体机能,促进头 发变黑, 变乌亮, 增进头发的弹性和光泽, 使头发疏松易梳。 临床实验 1:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2013 年 1月到 2013年 6月的 6个月时间。
2 )、观察对象:选择广东省深圳市中医院的 40例病例:男 20例, 女 20例; 年龄: 16— 25岁 18例, 25— 35岁 22例; 职业: 学生 10 例, 工人 10例, 农民 5例, 教师 10例, 其他 5例。 病程: 从发病到 就诊时间, 2年内 20例, 2— 4年 10例, 4年以上 10例。
3 )、 使用方法: 将本发明制剂混合其他市场上常见的洗发液清洗 头发, 每日 3次, 每次饭后 1小时清洗, 1个月为 1疗程, 6个疗程 作为疗效观察。
4)、 观察效果:
效果标准分为: 显著, 白发转黑 85%以上; 有效, 白发转黑 50% 以上, 白发得到控制; 无效, 白发基本没有改善和减轻。
结果 40例中, 显著 20例, 有效 13例, 无效 7例, 总有效率为 82. 5%。
临床实验 2:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2012 年 11月到 2013年 4月的 6个月时间。
2 )、 观察对象: 选择广东省深圳市中医院的选择 20例病例: 男 10例, 女 10例; 年龄: 16— 25岁 8例, 25— 35岁 12例; 职业: 学 生 10例, 工人 2例, 农民 2例, 教师 2例, 其他 4例。 病程: 从发 病到就诊时间, 2年内 10例, 2— 4年 5例, 4年以上 5例。
3 )、 使用方法: 将本发明制剂混合其他市场上常见的洗发液清洗
头发, 每日 3次, 每次饭前 1小时清洗, 1个月为 1疗程, 6个疗程 作为疗效观察。
4)、 观察效果:
效果标准分为: 显著, 白发转黑 85%以上; 有效, 白发转黑 50% 以上, 白发得到控制; 无效, 白发基本没有改善和减轻。
结果 20例中, 显著 14例, 有效 2例, 无效 4例, 总有效率为
80%。
结合以上临床数据及本发明的理论依据, 可见其有益效果在于, 本发明制成的制剂, 可以适用于各种特点的毛发和头皮, 用其清洗头 发后无过敏反应, 无毒副作用, 使药物能迅速渗入使皮肤吸收, 达到 乌发的目的, 而且见效快, 乌发养发效果好, 成本低廉、 制取工艺简 便易行。 具体实舫式
下面结合实施例对本发明详细加以说明:
实施例 1:
本发明制剂是由花生油、 白酒、 黑牛胆汁、 芝麻花、 芝麻梗、 牵 牛子、 槐豆、 白蒺藜、 青黛、 侧柏叶、 桑叶、 红花、 远志、 皂荚、 覆 盆子、 杏仁、 大麦、 西芹制备成的组合物膏状制剂,
其中各组分的质量配比为:
花生油 1200g 白酒 100g 黑牛胆汁 40g
芝麻花 20g 芝麻梗 60g 牵牛子 20g
槐豆 40g 白蒺藜 20g 黛 20
叶 20g 桑叶 20g 红花 30g
远志 30g 皂荚 20g 覆盆子 30g
杏仁 30g 大麦 30g 西芹 130g。
上述乌发中药制剂的制备方法, 包括如下步骤:
1 )、将芝麻花、 芝麻梗、 牵牛子、 槐豆、 白蒺藜、 青黛、 侧柏叶、 桑叶按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的 高温下烘干, 然后自然晾到室温备用;
2 )、将花生油放到铁锅内加热至 90-120摄氏度, 然后将芝麻花、 芝麻梗、 牵牛子、 槐豆、 白蒺藜、 青黛、 侧柏叶、 桑叶的粉末, 下入 油锅内与花生油同煎, 十五分钟后取出清油备用;
3 )、将上述清油放入陶瓷罐子内盛放, 然后加入黑牛胆汁和西芹
;出的西芹汁, 一直搅拌五分钟后, 静置经过至少一夜, 形成膏状制
4)、 将红花、 远志、 皂荚、 覆盆子、 .、 大麦按比例配好, 经 过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温下烘干, 然后自
6)、 将上述膏状制剂每日早、 晚各搅拌一次, 每次 10分钟, 三 日后微火煎半小时, 并静置到室温, 然后加入白酒, 并搅拌 10分钟, 最后装于瓷罐后即成。
制取的膏状制剂单独使用擦拭头皮或清洗头发,如果将其混入到 普通的洗发液中使用, 效果会更好。
实施例 2:
本发明还可优选的原料质量为 (克):
花生油 1600g 白酒 180g 黑牛胆汁 60g
芝麻花 40g 芝麻梗 80g 牵牛子 30g
槐豆 60g 白蒺藜 30g 青黛 30g
侧柏叶 30g 桑叶 30g 红花 40g
远志 40g 皂荚 30g 覆盆子 40g
杏仁 40g 40g 西芹 140g。
制备方法如实施例 1。
实施例 3:
其中各组分的质量为 (克):
花生油 1200g 白酒 180g 黑牛胆汁 40g
芝麻花 40g 芝麻梗 60g 牵牛子 30g
槐豆 40g 白蒺藜 30g 青黛 20g
侧柏叶 30g 桑叶 20g 红花 40g
远志 30g 皂荚 30g 覆盆子 30g
杏仁 40g ≠ 30g 西芹 130g。
制备方法如实施例 1。
实施例 4:
其中各组分的质量为 (克):
花生油 1300g 白酒 120g 黑牛胆汁 50g 芝麻花 25g 芝麻梗 65g 牵牛子 25g
青黛 25g
桑叶 30g 红花 40g
皂荚 20g 覆盆子 30g
西芹 135g。
花生油 1400g 白酒 120g 黑牛胆汁 50g
芝麻花 30g 芝麻梗 70g
槐豆 50g 白蒺藜 25g
侧柏叶 25g 桑叶 25g 红花 35g
远志 38g 皂荚 28g 覆盆子 28g
28g 西芹 120g。
制备方法如实施例 1。 上述实施例仅是本发明众多实施方式的几种,如将各配方按技术 方案中的比例加大或减小药量, 制得的这种乌发制剂疗效并不受影 响, 也将落在本发明的权利保护范围之内。
Claims
1、 一种促进乌发中药制剂的配方, 其特征在于, 本发明制剂是 由花生油、 白酒、 黑牛胆汁、 芝麻花、 芝麻梗、 牵牛子、 槐豆、 白蒺 藜、 青黛、 侧柏叶、 桑叶、 红花、 远志、 皂荚、 覆盆子、
西芹制备成的组合物膏状制剂,
其中各组分的质量配比为:
花生由 1200-1600g 白酒 100-180g 黑牛胆汁 40_60g 芝麻花 20-40g 芝麻梗 60-80g 牵牛子 20-30g 槐豆 40- 60g 白蒺藜 20-30g 青黛 20-30g 侧柏叶 20-30g 桑叶 20-30g 红花 30-40g 远志 30-40g 皂荚 20-30g 覆盆子 30-40g
30— 40g 大麦 30-40g 西芹 130-140gc
2、 根据权利要求 1所述的一种促进乌发中药制剂的配方, 其特 征还在于, 各组分的质量配比为:
为了获得更好的效果, 本发明可优选的原料质量配比为: 花生由 1400-1600g 白酒 160-180g 黑牛胆汁 50_60g 芝麻花 30-40g 芝麻梗 70-80g 牵牛子 20-25g 槐豆 30-60g 白蒺藜 25-30g 青黛 25-30g 侧柏叶 25-30g 桑叶 25-30g 红花 35-40g 远志 35-40g 皂荚 25-30g 覆盆子 35-40g
35-40g 大麦 35-40g 西芹 135-140g。
3、 根据权利要求 1或 2所述的一种促进乌发中药制剂的配方,
其特征还在于: 各组分的质量配比为
花生由 1600g 白酒 180g 黑牛胆汁 60g
芝麻花 40g 芝麻梗 75g
槐豆 40g 白蒺藜 25g
侧柏叶 25g 桑叶 25g 红花 35g
远志 35g 皂荚 30g 覆盆子 35g
35g 西芹 140gc
4、 一种促进乌发中药制剂的制备方法, 其特征在于, 其包括如 下步骤:
1 )、将芝麻花、 芝麻梗、 牵牛子、 槐豆、 白蒺藜、 青黛、侧柏叶、 桑叶按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的 高温下烘干, 然后自然晾到室温备用;
2 )、将花生油放到铁锅内加热至 90-120摄氏度, 然后将芝麻花、 芝麻梗、 牵牛子、 槐豆、 白蒺藜、 青黛、 侧柏叶、 桑叶的粉末, 下入 油锅内与花生油同煎, 十五分钟后取出清油备用;
3 )、将上述清油放入陶瓷罐子内盛放, 然后加入黑牛胆汁和西芹
;出的西芹汁, 一直搅拌五分钟后, 静置经过至少一夜, 形成膏状制
4)、 将红花、 远志、 皂荚、 覆盆子、 .、 大麦按比例配好, 经 过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温下烘干, 然后自
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310283376.3 | 2013-07-08 | ||
CN2013102833763A CN103301357A (zh) | 2013-07-08 | 2013-07-08 | 一种促进乌发中药制剂的配方及制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2015003309A1 true WO2015003309A1 (zh) | 2015-01-15 |
Family
ID=49127363
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2013/079038 WO2015003309A1 (zh) | 2013-07-08 | 2013-07-09 | 一种促进乌发的中药制剂及其制备方法 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN103301357A (zh) |
WO (1) | WO2015003309A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020198108A1 (en) | 2019-03-22 | 2020-10-01 | Biocompatibles Uk Limited | Embolic microspheres and methods |
US11744916B2 (en) | 2019-07-18 | 2023-09-05 | Biocompatibles Uk Limited | Radiopaque polymers |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104606366B (zh) * | 2015-01-12 | 2015-12-30 | 袁志贤 | 促进乌发的中药溶液及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1275398A (zh) * | 1999-06-01 | 2000-12-06 | 范忠志 | 华佗乌发再生精 |
CN102552096A (zh) * | 2011-09-23 | 2012-07-11 | 孙淑萍 | 一种乌发生发洗发液及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102526663A (zh) * | 2012-01-11 | 2012-07-04 | 杨长辉 | 一种治疗白发用的药物 |
CN102641353B (zh) * | 2012-05-15 | 2014-07-02 | 何超文 | 一种富含植物黄酮类物质的生发素 |
-
2013
- 2013-07-08 CN CN2013102833763A patent/CN103301357A/zh active Pending
- 2013-07-09 WO PCT/CN2013/079038 patent/WO2015003309A1/zh active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1275398A (zh) * | 1999-06-01 | 2000-12-06 | 范忠志 | 华佗乌发再生精 |
CN102552096A (zh) * | 2011-09-23 | 2012-07-11 | 孙淑萍 | 一种乌发生发洗发液及其制备方法 |
Non-Patent Citations (2)
Title |
---|
JIANG, HUACONG ET AL.: "Research and Efficacy Verification of Hair-blacking and Life-extending Medicine", ACTA CHINESE MEDICINE AND PHARMACOLOGY, vol. 29, no. 1, 31 January 2001 (2001-01-31), pages 33 - 35 * |
SHI, RONGBAO ET AL.: "Natural Plant Hair Dye", SHANGHAI CHEMICAL INDUSTRY, vol. 30, no. 6, 30 June 2005 (2005-06-30), pages 25 - 29 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020198108A1 (en) | 2019-03-22 | 2020-10-01 | Biocompatibles Uk Limited | Embolic microspheres and methods |
US11744916B2 (en) | 2019-07-18 | 2023-09-05 | Biocompatibles Uk Limited | Radiopaque polymers |
Also Published As
Publication number | Publication date |
---|---|
CN103301357A (zh) | 2013-09-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106579210A (zh) | 一种刺玫风味红参果果酱 | |
CN102698117B (zh) | 一种生发中药制剂及其制备方法 | |
KR20130086682A (ko) | 골장회복 하수오와 홍삼녹용과 오가피등 100가지한약재 추출물 드링크제 및제조 방법 | |
CN103027142B (zh) | 一种莞香花茶及其制作工艺 | |
CN104694353B (zh) | 女士用保健酒及其制备方法 | |
KR100939906B1 (ko) | 한방 추출액을 이용한 어류 양식용 사료첨가제 | |
CN104232446A (zh) | 一种墨米滋补酒的制备方法 | |
CN105010669A (zh) | 一种清润保健茉莉花茶及其生产方法 | |
CN104719416A (zh) | 一种燕麦饼干 | |
KR101334827B1 (ko) | 참외씨오일을 주성분으로 하는 미용 팩 제조방법 | |
WO2015003309A1 (zh) | 一种促进乌发的中药制剂及其制备方法 | |
CN104312875A (zh) | 一种小米滋补酒的制备方法 | |
KR101251976B1 (ko) | 성기능개선에 효과를 갖는 건강보조식품의 제조방법 | |
CN104041632A (zh) | 一种美容保健茶及其制备方法 | |
WO2015003307A1 (zh) | 一种促进生发中药制剂及制备方法 | |
CN105935090A (zh) | 一种龙甘酸五味茶凉茶饮料及其制备方法 | |
KR101391466B1 (ko) | 한약재를 이용한 사료첨가제 및 그 제조방법 | |
CN102698118A (zh) | 一种乌发中药制剂的配方及制备方法 | |
CN104544084A (zh) | 一种用于糖尿病患者的保健食品 | |
CN104893919A (zh) | 一种玉米滋补酒的制备方法 | |
CN108497169A (zh) | 一种畜禽用中草药添加剂及其制备方法 | |
CN104413320A (zh) | 一种睡莲花红枣果冻 | |
CN103444933B (zh) | 一种夏季养身中午茶袋泡茶 | |
CN107006717A (zh) | 含有桑叶和蚕的鸡饲料 | |
CN101156680A (zh) | 补血抗衰老的食品组合物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 13889159 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
32PN | Ep: public notification in the ep bulletin as address of the adressee cannot be established |
Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 1205A DATED 06/05/2016) |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 13889159 Country of ref document: EP Kind code of ref document: A1 |