WO2014079291A1 - 血栓过滤器及其使用方法 - Google Patents

血栓过滤器及其使用方法 Download PDF

Info

Publication number
WO2014079291A1
WO2014079291A1 PCT/CN2013/085167 CN2013085167W WO2014079291A1 WO 2014079291 A1 WO2014079291 A1 WO 2014079291A1 CN 2013085167 W CN2013085167 W CN 2013085167W WO 2014079291 A1 WO2014079291 A1 WO 2014079291A1
Authority
WO
WIPO (PCT)
Prior art keywords
umbrella
thrombus
overflow
intercepting net
intercepting
Prior art date
Application number
PCT/CN2013/085167
Other languages
English (en)
French (fr)
Inventor
訾振军
雷荣军
吕守良
张志飞
俞金虎
Original Assignee
杭州启明医疗器械有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 杭州启明医疗器械有限公司 filed Critical 杭州启明医疗器械有限公司
Priority to US14/646,091 priority Critical patent/US10687932B2/en
Priority to EP13856435.6A priority patent/EP2923673B1/en
Priority to ES13856435.6T priority patent/ES2645489T3/es
Priority to BR112015011796-1A priority patent/BR112015011796B1/pt
Priority to JP2015543265A priority patent/JP6034507B2/ja
Publication of WO2014079291A1 publication Critical patent/WO2014079291A1/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2/0105—Open ended, i.e. legs gathered only at one side
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2215—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having an open distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2/011—Instruments for their placement or removal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2002/016—Filters implantable into blood vessels made from wire-like elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/042—Force radial
    • F04C2270/0421—Controlled or regulated

Definitions

  • the present invention relates to a vascular filter and method of use thereof, and more particularly to a thrombus filter and method of use thereof.
  • thromb filter discloses a thrombus filter, including a thrombus intercepting net, a guide wire, and a distal connection.
  • the proximal end connector, the thrombus intercepting net adopts a funnel-shaped mesh structure of a coated nickel-titanium shape memory alloy wire with a filter hole, and the recovery line of the nickel-titanium memory alloy wire is connected to the mesh of the opening of the thrombus intercepting net.
  • the proximal connector, the tail of the thrombus intercepting mesh structure is connected to the distal connector, and the distal end of the distal connector is provided with a guiding head.
  • the opening of the thrombus interceptor is connected with the nickel-titanium memory alloy wire, so that the thrombus interceptor is closely attached to the inner wall of the blood vessel under the restoring force of the nickel-titanium memory alloy wire, thereby effectively filtering the thrombus; when retracting, the recovery line is first tightened
  • the opening of the funnel-shaped thrombus intercepting net can effectively prevent the thrombus from overflowing, thereby improving the recovery rate of the thrombus and reducing the risk of embolization of the coronary, brain and lower limbs, and has the advantages of simple structure, convenient operation, good filtering property, safety and reliability.
  • the advantages can be widely used in various angioplasty and thrombolytic surgery as anti-overflow, thrombus or shedding plaque, reducing the risk of
  • the above thrombus filter only discloses a case where the opening portion of the intercepting net faces the proximal end (control end), and the thrombus intercepting manner toward the distal end (away from the control end) of the opening portion of the intercepting net is not explained, and the technique is also Not effectively resolved.
  • the thrombus filter in the narrow vascular channel, how the thrombus filter can complete the thrombus or detachment plaque capture without disturbing the implantation process is a problem that should be solved.
  • the present invention provides a thrombus filter which can not only effectively prevent thrombus leakage when capturing thrombus withdrawal, but also has a simple structure and convenient operation.
  • the technical solution of the present invention is: a thrombus filter comprising a sheath tube, a thrombus intercepting net with an intercepting port, a first pushing member for driving the thrombus intercepting net into and out of the sheath tube, and a control for controlling the first pushing member handle,
  • the umbrella mouth of the anti-overflow umbrella is in the same direction as the intercepting port, and the anti-overflow umbrella is sleeved outside the thrombus intercepting net;
  • a second pushing member for pushing and pulling the overflow prevention umbrella in the sheath tube
  • the overflow prevention umbrella comprises an umbrella frame and a canopy surface, one end of the umbrella frame is connected with the second pushing member, the other end is connected with the umbrella surface, and the open end of the umbrella surface is a closed memory shape;
  • the umbrella surface of the anti-overflow umbrella covers the intercepting port of the thrombus intercepting net, and the open end of the umbrella surface is closed to prevent leakage of the thrombus.
  • the thrombus intercepting net and the anti-overflow umbrella are both a mesh structure, and the mesh structure is made of a memory alloy.
  • the thrombus intercepting net is a mesh structure
  • the anti-overflow umbrella is composed of an umbrella stand and a film with a filter hole covering the umbrella stand, and the umbrella stand is made of a memory alloy.
  • the thrombus intercepting net is a mesh structure
  • the umbrella surface of the anti-overflow umbrella is a mesh shape
  • the umbrella frame is a support rod connected to the umbrella surface
  • the umbrella surface is made of a memory alloy.
  • the thrombus intercepting net comprises a skeleton and a film with a filter hole covering the skeleton
  • the umbrella surface of the overflow umbrella is a mesh
  • the umbrella frame is a support rod connected to the umbrella surface
  • the umbrella The surface is made of a memory alloy.
  • the second pushing member is tubular, and the second pushing member is slidably sleeved on the first pushing member and disposed coaxially with the first pushing member.
  • the first pushing member is tubular, and the hollow portion in the first pushing member tube forms a conveying passage.
  • the umbrella surface is annular, and the outer edge of the ring is connected with the umbrella frame.
  • one end of the thrombus intercepting net is an intercepting port, and the other end is a mesh bottom, and the bottom part of the mesh extends into the sheath tube and is connected to the first pushing member.
  • the invention has the advantages that the overall structure is simple, the operation is convenient, the thrombus intercepting net and the anti-overflow umbrella can release the thrombus generated during the operation, and the anti-overflow net can effectively prevent the thrombus when capturing the thrombus withdrawal. leak.
  • the present invention provides a method of using a thrombus filter according to claim 1, comprising the steps of:
  • the beneficial effects of the invention are that compared with the prior art, the method of using the thrombus filter is simple in operation and convenient to use, not only has good filtering effect on the thrombus generated during the operation, but also can effectively prevent the thrombus when capturing the thrombus withdrawal. External leakage.
  • FIG. 1 is a schematic structural view of Embodiment 1 of the present invention.
  • FIG. 2 is a schematic structural diagram of Embodiment 2 of the present invention.
  • FIG. 3 is a schematic structural diagram of Embodiment 3 of the present invention.
  • Embodiment 4 is a schematic structural view of Embodiment 4 of the present invention.
  • Fig. 5 is a schematic view showing the structure of a thrombus filter according to a fifth embodiment of the present invention when it enters a blood vessel.
  • Fig. 6 is a schematic view showing the structure of a thrombus filter for capturing a thrombus according to a fifth embodiment of the present invention.
  • FIG. 7 is a schematic structural view of the thrombus filter intercepting net in the embodiment of the present invention.
  • Figure 8 is a schematic view showing the structure of the thrombus filter in the fifth embodiment of the present invention.
  • FIG. 9 is a partial schematic structural view of an embodiment of the present invention.
  • Figure 10 is a cross-sectional view of Figure 9.
  • the thrombus filter of the present invention comprises a sheath tube 1 and a control handle (not shown).
  • the sheath tube 1 houses a thrombus intercepting net 2 and an anti-overflow umbrella 3, and a thrombus, respectively.
  • the first pusher 4 and the second pusher 5 controlled by the control handle connected to the intercepting net 2 and the overflow prevention umbrella 3.
  • the first pushing member 4 and the second pushing member 5 are tubular, and the second pushing member 5 has a large diameter and coaxially sleeved outside the first pushing member 4;
  • the thrombus intercepting net 2 is a funnel-shaped, thrombus intercepting net 2 is an intercepting port at one end and a mesh bottom at the other end, and the bottom portion of the mesh is connected with the first pushing member 4 placed in the sheath tube 1;
  • the bottom portion of the mesh also has a port corresponding to the nozzle of the first pushing member 4
  • the port can be used as a passage for a balloon, an interventional instrument, and the like in the same path as the thrombus filter.
  • first pusher member 4 and the second pusher member 5 may also adopt a combination of columnar and tubular shapes, or other structures capable of realizing a push function, and these embodiments are all within the scope of the present invention.
  • the anti-overflow umbrella 3 is sleeved on the peripheral wall of the collapsed thrombus intercepting net 2, and the anti-overflow umbrella 3 can be divided into two parts: an umbrella stand 31 and a canopy 32, and the umbrella stand 31 is sleeved on the peripheral wall of the thrombus intercepting net 2.
  • the first pusher 4, the second pusher 5, the umbrella stand 31 and the end of the canopy 32 near the control handle are proximal, the end away from the control handle is the distal end, and the umbrella stand 31 is connected at the proximal end.
  • the distal end of the second pushing member 5; the proximal end of the umbrella surface 32 is connected to the distal end of the umbrella frame 31, the open end of the umbrella surface 32 is aligned with the intercepting port of the thrombus intercepting net 2, and the opening at the open end of the umbrella surface 32 is in an active converging state. Used to cover the interception port of the thrombus intercepting net 2.
  • memory alloy material has the advantages of non-magnetic, wear-resistant, corrosion-resistant and non-toxic. It is soft under austenitic phase when cooled, and is easily compressed into the bridge tube and released into Markov in the body. Body, restore the shape of the design.
  • the umbrella frame 31 and the umbrella surface 32 may be an integral structure, both of which are made of a memory alloy material, and the integrated structure is simple to manufacture and manufacture.
  • the umbrella frame 31 and the umbrella surface 32 can also be a combined structure, which are joined together by stitching or connecting pieces, further reducing consumables and overall size.
  • the material of the umbrella frame 31 and the umbrella surface 32 may also be different.
  • the umbrella frame 31 may be made of a material which is contracted in the original state to the axial direction of the sheath tube and has a flexible material, and the umbrella frame 31 follows the thrombus intercepting net 2 Open and close together and move together, especially after the thrombus intercepting net 2 is opened, the umbrella stand 31 will also be opened.
  • the control handle can operate the pushing and pulling of the first pushing member 4.
  • the control handle can be an intrinsic part of the proximal end of the first pushing member 4, or can be arranged separately from the first pushing member 4 and assembled.
  • the control handle not only controls the pushing movement of the thrombus intercepting net 2, but also controls the pushing movement of the sheath tube 1 and the overflow prevention umbrella 3, and controls the displacement of the supporting overflow prevention umbrella 3 through the second pushing member 5, and when the sheath tube 1 is retracted, the first The second pushing member 5 restricts the movement of the overflow prevention umbrella 3 and overcomes the backward frictional force.
  • the first pushing member 4 links the forward or backward movement of the thrombus intercepting net 2 in the sheath tube 1.
  • the sheath tube 1 transports the thrombus intercepting net 2 and the sheath tube 1 of the anti-overflow umbrella 3 to a designated position of the blood vessel I, the sheath tube 1 is retracted, and the relatively fixed second pushing member 5 and the first pushing member 4 are prevented from overflowing.
  • the umbrella 3 and the thrombus intercepting net 2 remain relatively stationary in the blood vessel.
  • the present invention includes at least the following four embodiments, but is not limited to the four embodiments disclosed below.
  • Embodiment 1 As shown in FIG. 1 , the thrombus intercepting net 2 (thick black line) and the anti-overflow umbrella 3 are all a mesh structure, and the mesh structure is woven by a memory alloy, wherein the thrombus intercepting net 2 is at body temperature. It is in an open state, and the anti-overflow umbrella 3 is in a converging state at body temperature, and the opening force generated by the thrombus intercepting net 2 under the opening trend is greater than the converging force in the confined state of the anti-overflow umbrella 3, that is, if the thrombus When the intercepting net 2 is opened at body temperature, the anti-overflow umbrella 3 is stressed and is opened by the thrombus intercepting net 2.
  • the open end of the umbrella surface 32 of the anti-overflow umbrella 3 is a closed memory shape, and the open end of the umbrella surface 32 can always be kept toward the center, that is, the cover of the intercepting port of the thrombus intercepting net 2 is realized.
  • the position of the thrombus intercepting net 2 from the distal end of the intercepting port is connected with the first pushing member 4, and the thrombus intercepting net 2 is freely pushed in the sheath tube 1 by the first pushing member 4; the umbrella stand 31 on the overflow preventing umbrella 3 It is connected to the second pushing member 5, and the overflow preventing umbrella 3 realizes free pushing in the sheath tube 1 through the second pushing member 5.
  • Embodiment 2 As shown in FIG. 2, the thrombus intercepting net 2 is a mesh structure which is woven by a memory alloy, and the thrombus intercepting net 2 is in an open state at body temperature.
  • the umbrella surface 32 of the anti-overflow umbrella 3 is a film with a filter hole, and the umbrella frame 31 (thick black line) is made of a strip-shaped memory alloy, and the umbrella frame 31 is arranged around the sheath tube 1 in the axial direction and the length direction of the umbrella frame 31
  • the distal end memory shape of the umbrella stand 31 is a curved arc of the axis, and the proximal end of the umbrella stand 31 is connected with the second pusher 5.
  • the distal end of the umbrella stand 31 is directed to the sheath 1
  • the direction of the axis is closed, wherein the canopy 32 is wrapped around the peripheral wall of the umbrella frame 31, and moves together as the umbrella frame 31 is opened and closed.
  • Embodiment 3 As shown in FIG. 3, the thrombus intercepting net 2 (thick black line) is a mesh structure, which is woven by a memory alloy, and the thrombus intercepting net 2 is in an open state at body temperature.
  • the umbrella surface 32 of the anti-overflow umbrella 3 is a mesh structure woven by a memory alloy wire, wherein the umbrella mouth memory state of the umbrella surface 32 is a collapsed state; the umbrella frame 31 (thick black line, which is thicker than the thrombus intercepting net 2)
  • the thicker line is a support rod connected to the canopy 32, and the two ends of the support rod are respectively connected to the second pusher 5 and the canopy 32.
  • the thrombus intercepting net 2 in the first, second and third embodiments can be woven by a supporting wire, which is formed by the expansion of the balloon; or can be made of a memory alloy material, under body temperature, Actively unfolding by restoring the expanded memory shape.
  • Embodiment 4 As shown in FIG. 4, the thrombus intercepting net 2 is composed of a skeleton 21 (thick black line) and a film 22 with a filter hole, wherein the film 22 is coated on the peripheral wall of the skeleton 21, and the skeleton 21 is strip-shaped.
  • the skeleton 21 Made of a memory alloy, one end of the skeleton 21 is connected to the first pushing member 4, and at a body temperature, a portion of the skeleton 21 away from the first pushing member 4 is tilted away from the axis of the sheath tube 1 with the coating 22 covered.
  • the skeleton 21 moves together as the skeleton 21 is opened and closed.
  • the umbrella surface 32 of the anti-overflow umbrella 3 is a mesh structure woven by a memory alloy wire, wherein the memory state of the umbrella surface 32 is a collapsed state; the umbrella frame 31 (a thick black line is thicker than the thick black line drawn by the skeleton 21)
  • the two ends of the support rod are respectively connected with the second pushing member 5 and the umbrella surface 32.
  • the skeleton of the thrombus intercepting net 2 in the fourth embodiment is a supporting metal rod which is formed by being expanded by a balloon; and can also be made of a memory alloy material, and recovering the expanded memory shape at a body temperature state. , active deployment.
  • the thrombus intercepting net 2 is composed of a skeleton 21 and a membrane 22 with a filter hole, wherein the coating 22 is coated on the peripheral wall of the skeleton 21, and the skeleton 21 is made of a strip-shaped memory alloy.
  • One end of the skeleton 21 is connected to the first pushing member 4, and at a body temperature, a portion of the skeleton 21 away from the first pushing member 4 is tilted away from the axis of the sheath tube 1, wherein the coating 22 is wrapped around the skeleton 21.
  • the skeleton 21 moves together as it expands and gathers.
  • the open end of the umbrella surface 32 of the anti-overflow umbrella 3 is a closed memory shape, and the open end of the umbrella surface 32 can always be kept toward the center, that is, the cover of the intercepting port of the thrombus intercepting net 2 is realized.
  • the film in the above embodiments is a polymer material film
  • the polymer material film generally refers to a medical polymer material film, such as a medical polytetrafluoroethylene film, a medical polyurethane film, a medical silicone film, and the like.
  • the thrombus intercepting net 2 and the overflow preventing umbrella 3 may have other protected structures in addition to the above-described structural combination, and are not limited to the five cases in the embodiment.
  • the first step as shown in Figure 5 (the thrombus intercepting net 2 and the anti-overflow umbrella 3 are in an overlapping state and located in the sheath 1), the thrombus filter enters the blood vessel I, and the sheath 1 carries the thrombus intercepting net 2 and the prevention
  • the overflow umbrella 3 is delivered to a designated position within the blood vessel I.
  • the direction of the arrow is the direction in which the blood mixed with the thrombus 6 flows.
  • the second step as shown in FIG. 6 (the thrombus intercepting net 2 and the anti-overflow umbrella 3 are in an overlapping state and partially exposed outside the sheath tube 1 at this time, the thrombus intercepting net 2 and the anti-overflow umbrella 3 are the same part in the figure, There is no significant difference), the thrombus filter captures the thrombus 6, and when the sheath 1 carries the thrombus intercepting net 2 and the anti-overflow umbrella 3 to a specified position in the blood vessel I, then the sheath 1 is pulled to retreat, and at the same time A pushing member 4 and a second pushing member 5 push the anti-overflow umbrella 3 and the thrombus intercepting net 2, so that the anti-overflow umbrella 3 and the thrombus intercepting net 2 overcome the retreating force (the force mainly refers to the frictional force) and maintain the original
  • the position is immobile, that is, the pushing of the first pusher 4 and the second pusher 5 causes the overflow prevention umbrella 3 and the thrombus intercept
  • the intravascular thrombus intercepting net 2 is actively deployed; if it is made of stainless steel, it should pass first.
  • the balloon dilates the thrombus intercepting mesh 2 to a suitable size; at the same time, the anti-overflow umbrella 3 sleeved on the peripheral wall of the thrombus intercepting net 2 will also be distracted.
  • the channel II of the die of the second pusher 5 is used to carry out the steps of transporting, placing and withdrawing the surgical instrument, and the whole process is performed under the protective state.
  • the third step as shown in Figure 7, the thrombus filter intercepts the net back.
  • the thrombus 6 is pulled by the first pusher 4 to return to the sheath 1 through the first pusher 4, during which the thrombus intercepting net 2 and the anti-overflow umbrella 3 are in the thrombus interception.
  • the intercepting ports of the net 2 are staggered from each other, that is, the thrombus intercepting net 2 is moved back into the anti-overflow umbrella 3, and the anti-overflow umbrella 3 is stationary with respect to the blood vessel I, thereby avoiding the blood vessel I caused by the thrombus intercepting net 2 during the retreating process.
  • the anti-overflow umbrella 3 is moved forward relative to the thrombus intercepting net 2, and the umbrella surface 32 is shrouded on the intercepting port of the thrombus intercepting net 2 under the concomitant memory shape. According to the staggered distance, the portion where the anti-overflow umbrella 3 surface 32 coincides with the thrombus intercepting net 2 will gradually and completely separate, and at this time, the umbrella surface 32 gradually covers the entire intercepting port of the thrombus intercepting net 2.
  • the umbrella surface 32 of the anti-overflow umbrella 3 will exceed the intercepting port of the thrombus intercepting net 2 and be gathered toward the center of the intercepting port to realize the covering of the intercepting port, which is equivalent to the reduction of the caliber of the intercepting port in the umbrella surface 32, thereby forming a A structure similar to the lid encloses the intercepting port, thereby preventing the thrombus 6 from easily escaping from the intercepting opening.
  • the thrombus intercepting net 2 is not fully in place, that is, the spill net 3 has not completely covered the intercepting port of the thrombus intercepting net 2, and the thrombus intercepting net 2 needs to be retracted until the overflow net 3 is completely shrouded.
  • the sheath 1 starts to push forward to recover the anti-frozen net 3 and the thrombus intercepting net 2.
  • the first pushing member 4 continues to pull the thrombus intercepting net 2 until the umbrella opening of the anti-overflow umbrella 3 is completely closed, and the anti-overflow umbrella 3 can completely avoid the overflow of the thrombus 6 in the thrombus intercepting net 2.
  • the fourth step as shown in Fig. 8, the thrombus filter is retracted, and after the umbrella opening of the anti-overflow umbrella 3 is completely closed, the sheath tube 1 is pushed to move forward, and the anti-overflow umbrella 3 gradually overflows from the rear. 3 It is completely stored in the sheath tube 1 and can simultaneously filter the blood in the blood vessel I, and can also solve the problem of overflow of the thrombus 6 when the thrombus intercepting net 2 is recovered, and ensure the stability and safety of the environment inside the blood vessel I.
  • the mucosa of the inner wall of the protective blood vessel I is very delicate, when the anti-overflow umbrella 3 is outside the sheath tube 1 and is located inside the blood vessel I, there is no relative movement between the anti-overflow umbrella 3 and the blood vessel I, otherwise the outer wall of the anti-overflow umbrella 3 is very It is easy to scratch the inner wall of the blood vessel I, thereby causing injury or lesion of the blood vessel I, so that the release and recovery of the thrombus intercepting net 2 and the anti-overflow umbrella 3 are mainly achieved by the relative retreat and advancement of the sheath tube 1. Further, in order to further protect the inner wall of the blood vessel I, the curved portion of the overflow prevention umbrella 3 and the thrombus intercepting net 2 in the memory state is a curved surface structure.
  • Step 5 The sheath 1 containing the thrombus intercepting net 2 and the overflow preventing umbrella 3 is withdrawn from the blood vessel I.
  • the umbrella surface 32 has at least the following three states. Before the thrombus intercepting net 2 is released, the umbrella surface 32 is in the sheath tube 1 and is sleeved on the peripheral wall of the thrombus intercepting net 2; when the thrombus intercepting net 2 is released, the canopy surface 32 is located at the periphery of the thrombus intercepting net 2 and is expanded by the thrombus intercepting net 2; when the thrombus intercepting net 2 is recovered, the umbrella surface 32 is gathered by the periphery of the intercepting opening of the thrombus intercepting net 2 toward the center of the intercepting opening to form a shroud of the intercepting opening.
  • the overall structure of the invention is simple and convenient to operate. After the thrombus intercepting net 2 and the anti-overflow umbrella 3 are released, the thrombus generated during the operation can be effectively recovered, and the anti-overflow net 3 can effectively prevent the leakage of the thrombus 6 when retracting. .

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgical Instruments (AREA)

Abstract

一种血栓过滤器，包括鞘管（1）、带有拦截口的血栓拦截网（2）、第一推送件（4）及控制手柄，还设有防溢伞（3），防溢伞（3）的伞口方向与拦截口同向，防溢伞（3）套设在血栓拦截网（2）外，第二推送件（5）处在所述鞘管（1）内用于推拉防溢伞（3）。所述防溢伞（3）包括伞面（32），及连接于第二推送件（5）和伞面（32）间的伞架（31），伞面（32）开口端为收束的记忆形状。在过滤血管中血栓时，防溢伞（3）被血栓拦截网（2）撑开；过滤结束后，血栓拦截网（2）退回防溢伞（3）内，防溢伞（3）的伞面（32）将向拦截口中心收拢，实现对拦截口的完全笼罩，以防止斑块的溢出；前推鞘管（1）实现对血栓拦截网（2）的回收；将防溢伞（3）拉进鞘管（1）内。该血栓过滤器通过血栓拦截网（2）能有效回收血管中钙化斑块，而防溢伞（3）能在捕捉血栓回撤时，有效防止血栓外漏。

Description

血栓过滤器及其使用方法 技术领域
本发明涉及一种血管滤器及其使用方法，尤其是一种血栓过滤器及其使用方法。
 背景技术
随着介入手术在世界范围内的广泛应用，其并发症也日益显现。以介入主动脉瓣膜置换手术为例，由于主动脉严重狭窄钙化，需要通过主动脉瓣膜能支撑并置换原有主动脉瓣，但大多数严重狭窄钙化后的主动脉会导致血流通道的内径变小，此时，一般先采用球囊预先对原钙化瓣膜进行扩张，在此过程中，会有部分钙化的斑块在扩张过程中脱落，或手术过程中产生的血栓会随着血液流动进入冠脉、脑部及下肢等血管，导致血管栓塞，最终导致病人死亡或者瘫痪。
为了解决上述问题，中国专利公开号为CN1515326A，公开日为2004年7月28日，专利名称为“血栓过滤器”中公开了一种血栓过滤器，包括血栓拦截网、导丝、远端连接件、近端连接件，血栓拦截网采用带过滤孔的覆膜镍钛形状记忆合金丝的漏斗形网状结构，镍钛记忆合金丝的回收线穿绕血栓拦截网开口部的网孔后连接近端连接件，血栓拦截网网状结构的尾部连接远端连接件，远端连接件前端设有导向头。血栓拦截器的开口部与镍钛记忆合金丝连接，可使得血栓拦截器在镍钛记忆合金丝的回复力作用下紧贴血管内壁，从而有效过滤血栓；在回撤时，回收线先收紧漏斗形血栓拦截网的开口，能有效防止血栓溢出，由此提高血栓的回收率，降低冠脉、脑部及下肢等血管处栓塞的风险，具有结构简单、操作方便、过滤性好、安全可靠的优点，可广泛用于各种血管成形术及血栓溶解术中作为防溢伞，血栓或脱落的斑块，降低手术风险，提高手术成功率。
上述血栓过滤器只公开了拦截网开口部朝向近端（控制端）的一种情况，而对于拦截网开口部朝向远端（远离控制端）的血栓拦截方式并未进行说明，且该技术还未得到有效解决。同时，在狭窄的血管通道中，血栓过滤器如何既能完成血栓或脱落斑块抓捕，又不会对植入过程造成干扰，是应解决的问题。
 技术问题
为了克服现有技术的不足，本发明提供了一种在捕捉血栓回撤时，不仅能有效防止血栓外漏，而且结构简单，操作方便的血栓过滤器。
 技术解决方案
本发明技术方案是：一种血栓过滤器，包括鞘管、带有拦截口的血栓拦截网、用于驱动血栓拦截网进出鞘管的第一推送件，以及用于控制第一推送件的控制手柄，
还设有防溢伞，防溢伞的伞口方向与拦截口同向，防溢伞套设在血栓拦截网外；
处在所述鞘管内用于推拉防溢伞的第二推送件；
所述防溢伞包括伞架和伞面，伞架的一端与第二推送件连接，另一端与伞面连接，伞面开口端为收束的记忆形状；
血栓拦截网释放时，防溢伞的伞口被血栓拦截网的拦截口撑开；
血栓拦截网回退时，防溢伞的伞面笼罩血栓拦截网的拦截口，且伞面开口端收束以防止血栓外漏。
优选的，所述血栓拦截网和防溢伞均为网状结构，该网状结构为记忆合金制成。
优选的，所述血栓拦截网为网状结构，所述防溢伞由伞架和覆盖在伞架上的带过滤孔的覆膜组成，伞架为记忆合金制成。
优选的，所述血栓拦截网为网状结构，所述防溢伞的伞面为网状，所述伞架为与伞面连接的支撑杆，伞面为记忆合金制成。
优选的，所述血栓拦截网包括骨架和覆盖在骨架上的带过滤孔的覆膜组成，所述防溢伞的伞面为网状，所述伞架为与伞面连接的支撑杆，伞面为记忆合金制成。
优选的，所述第二推送件为管状，第二推送件滑动地套设于第一推送件上，并与第一推送件同轴设置。
优选的，所述第一推送件为管状，第一推送件管内的中空部分形成输送通道。
优选的，所述伞面为环形，环形的外缘与伞架连接。
优选的，所述血栓拦截网一端为拦截口，另一端为网底，网底部分伸入鞘管内且与所述的第一推送件相连。
本发明的有益效果是，整体结构简单，操作方便，血栓拦截网和防溢伞释放时，能有效回收手术过程中产生的血栓，而防溢网在捕捉血栓回撤时，能有效防止血栓外漏。
本发明提供了一种根据权利要求1所述的血栓过滤器的使用方法，包含以下步骤：
（1）将装有血栓拦截网和防溢伞的鞘管输送至需要捕捉血栓的血管位置；
（2）回撤鞘管，使得拦截网和防溢伞裸露于鞘管外而实现一起释放，血栓拦截网的拦截口张开，同时撑开防溢伞的伞口，血栓拦截网逆着血流捕捉血栓；
（3）待血栓捕捉结束时，通过第一推送件将血栓拦截网回退，防溢伞的伞面相对于血栓拦截网向前位移并笼罩拦截口，伞面开口端在记忆形状的收束力下收束以防止血栓外漏；
（4）待防溢伞的伞口完全收束后，前推鞘管使其将防溢伞回收进鞘管内；
（5）将装有血栓拦截网和防溢伞的鞘管撤出血管。
本发明的有益效果是，相较现有技术，血栓过滤器的使用方法操作简单，使用方便，不仅对手术过程中产生的血栓的过滤效果好，而且在捕捉血栓回撤时，能有效防止血栓外漏。
 附图说明
图1为本发明实施例一的结构示意图。
图2为本发明实施例二的结构示意图。
图3为本发明实施例三的结构示意图。
图4为本发明实施例四的结构示意图。
图5为本发明实施例五血栓过滤器进入血管时的结构示意图。
图6为本发明实施例五血栓过滤器捕捉血栓时的结构示意图。
图7为本发明实施例五血栓过滤器拦截网后退时的结构示意图。
图8为本发明实施例五血栓过滤器回撤时的结构示意图。
图9为本发明实施例的局部结构示意图。
图10为图9的剖视图。
 本发明的实施方式
以下结合说明书附图及具体实施例进一步说明本发明的技术方案。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。
如图1-10所示，本发明血栓过滤器包括鞘管1和控制手柄（未画出），初始状态时，鞘管1内收纳有血栓拦截网2和防溢伞3，及分别与血栓拦截网2和防溢伞3连接的受控制手柄控制的第一推送件4和第二推件5。其中，第一推送件4和第二推送件5为管状，第二推送件5管径较大且同轴地套设于第一推送件4外；血栓拦截网2为漏斗状，血栓拦截网2一端为拦截口，另一端为网底，网底部分与置于鞘管1内的第一推送件4相连；网底部分还带有与第一推送件4的管口相对应的通口，该通口可作为球囊、介入器械等与血栓过滤器同路径时的通道。由此，当需要往血管内输入球囊、介入器械等时，就无需在血管I上另外开口，这样有助于降低对人体的伤害。当然，第一推送件4和第二推送件5还可以采用柱状和管状间的配合，或者其他能实现推送功能的结构，这些实施方案均落于本发明的保护范围内。
防溢伞3被套设于收拢后的血栓拦截网2周壁上，且防溢伞3可划分为伞架31和伞面32两部分，伞架31套设在血栓拦截网2的周壁上。本发明中，第一推送件4、第二推送件5、伞架31和伞面32上靠近控制手柄的端部为近端，远离控制手柄的端部为远端，伞架31近端连接第二推送件5远端；伞面32近端连接在伞架31远端，伞面32开口端与血栓拦截网2拦截口朝向一致，伞面32开口端处的开口为主动收束状态，用于对血栓拦截网2拦截口的笼罩。
记忆合金材料作为一种新兴的材料，具有无磁性、耐磨耐蚀、无毒性很的优点，其在冷却时奥氏体相状态下柔软，很容易压缩至桥管内，在体内释放进入马氏体相，恢复设计的形状。
为了便于工艺上的实施，伞架31和伞面32可以为一体结构，两者均为记忆合金材料制成，一体结构生产制作简单。此外，伞架31和伞面32还可以为组合式结构，两者通过缝合或连接件的方式连接在一起，进一步减低耗材和整体尺寸。而且伞架31和伞面32的材料也可不一样，伞架31可以采用一种原始状态向鞘管轴线方向收缩的，且具有挠性的材料制成，伞架31随着血栓拦截网2的张开和收拢而一起运动，特别是血栓拦截网2张开后，伞架31也会被撑开。
控制手柄可以对第一推送件4的推拉进行操作，同时，该控制手柄可以为第一推送件4上近端的固有部分，也可以与第一推送件4分体结构且装配布置。控制手柄不仅可控制血栓拦截网2的推送运动，还可以控制鞘管1和防溢伞3的推送运动，通过第二推送件5控制支撑防溢伞3位移，回撤鞘管1时，第二推送件5限制防溢伞3移动并使其克服向后的摩擦力，同理，第一推送件4联动血栓拦截网2在鞘管1内的前进或后退运动。当鞘管1将血栓拦截网2和防溢伞3的鞘管1输送至血管I的指定位置后，回撤鞘管1，相对固定的第二推送件5和第一推送件4使防溢伞3和血栓拦截网2保持相对静止放置于血管中。
根据血栓拦截网2和防溢伞3的特性，本发明至少包括如下四种实施例，但不局限于下面所公布的四种实施例。
实施例一：如图1所示，血栓拦截网2（粗黑线）和防溢伞3均为网状结构，该网状结构采用记忆合金编织而成，其中，血栓拦截网2在体温下是张开状态，而防溢伞3在体温下是收束状态，且血栓拦截网2在张开趋势下所产生的张开力大于防溢伞3收束状态下的收束力，也即如果血栓拦截网2在体温下张开时，防溢伞3会受力并被血栓拦截网2撑开。防溢伞3上伞面32开口端为收束的记忆形状，伞面32的开口端能始终保持向中央收拢，也即实现对血栓拦截网2拦截口的笼罩。血栓拦截网2上距拦截口远端的位置和第一推送件4连接，且血栓拦截网2通过第一推送件4而实现在鞘管1内的自由推送；防溢伞3上伞架31与第二推送件5连接，且防溢伞3通过第二推送件5而实现在鞘管1内的自由推送。
实施例二：如图2所示，血栓拦截网2为网状结构，该网状结构采用记忆合金编织而成，血栓拦截网2在体温下是张开状态。防溢伞3的伞面32为带过滤孔的覆膜，伞架31（粗黑线）为条状的记忆合金制成，伞架31环绕鞘管1轴向排布且伞架31长度方向与鞘管1方向相一致，伞架31远端记忆形状为弯向轴心圆弧，伞架31的近端与第二推送件5连接，在体温下，伞架31远端向鞘管1轴线的方向收拢，其中伞面32包覆于伞架31周壁上，随着伞架31的张开和收拢而一起运动。
实施例三：如图3所示，血栓拦截网2（粗黑线）为网状结构，该网状结构采用记忆合金编织而成，血栓拦截网2在体温下是张开状态。防溢伞3上伞面32为记忆合金丝编织而成的网状结构，其中伞面32的伞口记忆状态为收拢状态；伞架31（粗黑线，较血栓拦截网2所画粗黑线更粗）为与伞面32连接的支撑杆，该支撑杆两端分别与第二推送件5和伞面32连接。
实施例一、二、三中的血栓拦截网2可为具有支撑力的金属丝编织而成，其展开是通过球囊撑开而成形；也可采用记忆合金材料制成，在体温状态下，通过恢复撑开的记忆形状，主动展开。
实施例四：如图4所示，血栓拦截网2由骨架21（粗黑线）和带过滤孔的覆膜22组成，其中覆膜22包覆于骨架21周壁上，骨架21为条状的记忆合金制成，骨架21的一端与第一推送件4连接，在体温下，骨架21上远离第一推送件4的部位会向远离鞘管1轴线的方向翘起，其中覆膜22包覆于骨架21周壁上，随着骨架21的张开和收拢而一起运动。防溢伞3上伞面32为记忆合金丝编织而成的网状结构，其中伞面32的记忆状态为收拢状态；伞架31（粗黑线，较骨架21所画粗黑线更粗）为与伞面32连接的支撑杆，该支撑杆两端分别与第二推送件5和伞面32连接。
实施例四中的血栓拦截网2的骨架为具有支撑力的金属杆，其展开通过球囊撑开而成形；也可采用记忆合金材料制成，在体温状态下，通过恢复撑开的记忆形状，主动展开。
实施例五：如图5-8所示，血栓拦截网2由骨架21和带过滤孔的覆膜22组成，其中覆膜22包覆于骨架21周壁上，骨架21为条状的记忆合金制成，骨架21的一端与第一推送件4连接，在体温下，骨架21上远离第一推送件4的部位会向远离鞘管1轴线的方向翘起，其中覆膜22包覆于骨架21周壁上，随着骨架21的张开和收拢而一起运动。防溢伞3上伞面32开口端为收束的记忆形状，伞面32的开口端能始终保持向中央收拢，也即实现对血栓拦截网2拦截口的笼罩。
上述种实施例中的覆膜为高分子材料薄膜，高分子材料薄膜通常指医用高分子材料薄膜，如医用聚四氟乙烯薄膜、医用聚氨酯薄膜、医用硅胶薄膜等。此外，血栓拦截网2和防溢伞3除了上述的结构组合外，还可以有其他受权利保护的结构，并不仅局限于实施例中的五种情况。
本发明中，虽然具有多种实施例存在，但是各实施例的操作步骤和原理还是相同的，且在下面针对实施例五对血栓过滤器的使用方法进行具体描述。
第一步：如图5所示（图中血栓拦截网2和防溢伞3处于重叠状态并位于鞘管1内），血栓过滤器进入血管I，鞘管1载着血栓拦截网2和防溢伞3输送到血管I内的指定位置。箭头方向为混有血栓6的血液流经方向。
第二步：如图6所示（血栓拦截网2和防溢伞3处于重叠状态并部分裸露于鞘管1外，此时，血栓拦截网2和防溢伞3在图中为同一部分，未有明显区别），血栓过滤器捕捉血栓6，当鞘管1载着血栓拦截网2和防溢伞3运动到血管I内的指定位置后，接着拉动鞘管1使其后退，同时通过第一推送件4、第二推送件5对防溢伞3和血栓拦截网2进行推送，使防溢伞3和血栓拦截网2克服后退的作用力（该作用力主要指摩擦力）而保持原位不动，即通过第一推送件4和第二推送件5的推动，使得防溢伞3和血栓拦截网2与血管I保持相对静止。
此时，若血栓拦截网2为记忆合金材料制得，且血栓拦截网2的原始状态为张开状态，在血管内血栓拦截网2网口主动展开；若采用不锈钢金属制成，应先通过球囊扩张血栓拦截网2至适宜的大小；与此同时，套设于血栓拦截网2周壁上的防溢伞3也将被撑开。
根据需要，在血栓拦截网2和防溢伞3释放后，通过第二推送件5管芯的通道II，再进行手术器械的输送、放置和回撤步骤，全过程都在保护状态下进行。
第三步：如图7所示，血栓过滤器拦截网后退。当器械植入过程完成后，配合的血栓6捕捉工作结束时，通过第一推送件4拉动血栓拦截网2退回鞘管1内，在这个过程中血栓拦截网2和防溢伞3在血栓拦截网2拦截口处相互错开，也即血栓拦截网2后移回退进入防溢伞3内，而防溢伞3相对血管I静止，避免了血栓拦截网2回退过程中对血管I造成的伤害，而防溢伞3相对血栓拦截网2前移，伞面32在收束的记忆形状下笼罩在血栓拦截网2的拦截口上。根据错开的距离，会出现防溢伞3伞面32与血栓拦截网2相重合的部分逐渐至全部分离，此时伞面32则逐渐至全部笼罩在血栓拦截网2的拦截口处。也即防溢伞3的伞面32将超出血栓拦截网2的拦截口并向拦截口中心收拢，实现对拦截口的笼罩，相当于拦截口的口径在伞面32的作用缩小，从而形成一个类似于盖子的结构将拦截口笼罩上，由此避免血栓6从拦截口处轻易地溢出。当防溢伞上伞口开口端因自身收束的记忆形状而完全闭合（可以未完全封闭，因为由于收束而收拢的开口已经很小，不会出现血栓6溢出的情况发生，所以近似于理解为开口端的完全闭合状态），从血管I中过滤得到的血栓6被防溢伞3所封闭在血栓拦截网2内。图7中，血栓拦截网2还未完全到位，也即防溢网3还未完全笼罩住血栓拦截网2的拦截口，此时血栓拦截网2还需后退，直至防溢网3完全笼罩住血栓拦截网2的拦截口后，鞘管1才开始前推以回收防溢网3和血栓拦截网2。
本发明中，防溢伞3上伞面32和伞架31间的区分界限没有明确的要求，只要能在上述情况下，实现伞面32对拦截口的笼罩即可。其中，防溢伞3上伞面32与血栓拦截网2拦截口相互错开后，凡是悬于拦截口外的部分均会在收束作用力下向拦截口中心笼罩，实现对拦截口口径的缩小，从而避免将血栓拦截网3和防溢伞3回收进鞘管1时，血栓6从拦截口处溢出。第一推送件4继续拉着血栓拦截网2，直至防溢伞3的伞口完全收束，此时防溢伞3能完全避免血栓拦截网2内的血栓6溢出。
第四步：如图8所示，血栓过滤器回撤，待防溢伞3的伞口完全收束后，推动鞘管1使其向前移，防溢伞3从后方逐渐将防溢伞3完全收纳于鞘管1内，在实现对血管I内血液进行过滤的同时，还能解决回收血栓拦截网2时血栓6的溢出问题，保证血管I内环境的稳定和安全。由于保护血管I内壁粘膜十分娇嫩，当防溢伞3处于鞘管1外，且位于血管I内时，防溢伞3和血管I间是不能有相对移动的，否则防溢伞3的外壁很容易划伤血管I内壁，从而造成血管I的受伤乃至病变，所以对于血栓拦截网2和防溢伞3的释放和回收时，主要通过鞘管1的相对后退和前进来实现的。另外，为了进一步保护血管I内壁，防溢伞3和血栓拦截网2在记忆状态时的弯曲部位为弧面结构。
第五步：将装有血栓拦截网2和防溢伞3的鞘管1撤出血管I。
本发明中，伞面32至少具有如下三种状态，血栓拦截网2释放前，伞面32处在鞘管1内且套设于血栓拦截网2周壁上；血栓拦截网2释放时，伞面32处在血栓拦截网2外围且受血栓拦截网2支撑而扩张；血栓拦截网2回收时，伞面32由血栓拦截网2拦截口周边向拦截口中心收拢形成对拦截口的笼罩。本发明的整体结构简单，操作方便，血栓拦截网2和防溢伞3释放后，能有效回收手术过程中产生的血栓6，且防溢网3在回撤时，能有效防止血栓6外漏。

Claims (10)

  1. 一种血栓过滤器，包括鞘管、带有拦截口的血栓拦截网、用于驱动血栓拦截网进出鞘管的第一推送件，以及用于控制第一推送件的控制手柄，其特征是：
    还设有防溢伞，防溢伞的伞口方向与拦截口同向，防溢伞套设在血栓拦截网外；
    处在所述鞘管内用于推拉防溢伞的第二推送件；
    所述防溢伞包括伞架和伞面，伞架的一端与第二推送件连接，另一端与伞面连接，伞面开口端为收束的记忆形状；
    血栓拦截网释放时，防溢伞的伞口被血栓拦截网的拦截口撑开；
    血栓拦截网回退时，防溢伞的伞面笼罩血栓拦截网的拦截口，且伞面开口端收束以防止血栓外漏。
  2. 根据权利要求1所述的血栓过滤器，其特征是：所述血栓拦截网和防溢伞均为网状结构，该网状结构为记忆合金制成。
  3. 根据权利要求1所述的血栓过滤器，其特征是：所述血栓拦截网为网状结构，所述防溢伞由伞架和覆盖在伞架上的带过滤孔的覆膜组成，伞架为记忆合金制成。
  4. 根据权利要求1所述的血栓过滤器，其特征是：所述血栓拦截网为网状结构，所述防溢伞的伞面为网状，所述伞架为与伞面连接的支撑杆，伞面为记忆合金制成。
  5. 根据权利要求1所述的血栓过滤器，其特征是：所述血栓拦截网包括骨架和覆盖在骨架上的带过滤孔的覆膜组成，所述防溢伞的伞面为网状，所述伞架为与伞面连接的支撑杆，伞面为记忆合金制成。
  6. 根据权利要求1~5任意一项所述的血栓过滤器，其特征是：所述第二推送件为管状，第二推送件滑动地套设于第一推送件上，并与第一推送件同轴设置。
  7. 根据权利要求6所述的血栓过滤器，其特征是：所述第一推送件为管状，第一推送件管内的中空部分形成输送通道。
  8. 根据权利要求1所述的血栓过滤器，其特征是：所述伞面为环形，环形的外缘与伞架连接。
  9. 根据权利要求1所述的血栓过滤器，其特征是：所述血栓拦截网一端为拦截口，另一端为网底，网底部分伸入鞘管内且与所述的第一推送件相连。
  10. 一种根据权利要求1所述的血栓过滤器的使用方法，其特征是：包含以下步骤：
    （1）将装有血栓拦截网和防溢伞的鞘管输送至需要捕捉血栓的血管位置；
    （2）回撤鞘管，使得拦截网和防溢伞裸露于鞘管外而实现一起释放，血栓拦截网的拦截口张开，同时撑开防溢伞的伞口，血栓拦截网逆着血流捕捉血栓；
    （3）待血栓捕捉结束时，通过第一推送件将血栓拦截网回退，防溢伞的伞面相对于血栓拦截网向前位移并笼罩拦截口，伞面开口端在记忆形状的收束力下收束以防止血栓外漏；
    （4）待防溢伞的伞口完全收束后，前推鞘管使其将防溢伞回收进鞘管内；
    （5）将装有血栓拦截网和防溢伞的鞘管撤出血管。
PCT/CN2013/085167 2012-11-23 2013-10-14 血栓过滤器及其使用方法 WO2014079291A1 (zh)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US14/646,091 US10687932B2 (en) 2012-11-23 2013-10-14 Thrombus filter and utilization method thereof
EP13856435.6A EP2923673B1 (en) 2012-11-23 2013-10-14 Blood clot filter
ES13856435.6T ES2645489T3 (es) 2012-11-23 2013-10-14 Filtro para coágulo de sangre
BR112015011796-1A BR112015011796B1 (pt) 2012-11-23 2013-10-14 Filtro de trombo
JP2015543265A JP6034507B2 (ja) 2012-11-23 2013-10-14 血栓フィルター及びその使用方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201210484480.4A CN102973332B (zh) 2012-11-23 2012-11-23 血栓过滤器及其使用方法
CN201210484480.4 2012-11-23

Publications (1)

Publication Number Publication Date
WO2014079291A1 true WO2014079291A1 (zh) 2014-05-30

Family

ID=47847876

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2013/085167 WO2014079291A1 (zh) 2012-11-23 2013-10-14 血栓过滤器及其使用方法

Country Status (7)

Country Link
US (1) US10687932B2 (zh)
EP (1) EP2923673B1 (zh)
JP (1) JP6034507B2 (zh)
CN (1) CN102973332B (zh)
BR (1) BR112015011796B1 (zh)
ES (1) ES2645489T3 (zh)
WO (1) WO2014079291A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115068064A (zh) * 2022-07-19 2022-09-20 深圳佰特微医疗科技有限公司 取栓装置

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8114114B2 (en) 2002-08-27 2012-02-14 Emboline, Inc. Embolic protection device
EP2129425B1 (en) 2006-11-29 2023-12-27 Emboline, INC. Embolic protection device
US9402707B2 (en) 2008-07-22 2016-08-02 Neuravi Limited Clot capture systems and associated methods
ES2683943T3 (es) 2010-10-22 2018-09-28 Neuravi Limited Sistema de captura y extirpación de coágulos
US9492265B2 (en) 2012-01-06 2016-11-15 Emboline, Inc. Integrated embolic protection devices
CN102973332B (zh) * 2012-11-23 2015-01-21 杭州启明医疗器械有限公司 血栓过滤器及其使用方法
ES2960917T3 (es) 2013-03-14 2024-03-07 Neuravi Ltd Dispositivo de recuperación de coágulos para eliminar coágulos oclusivos de un vaso sanguíneo
US9433429B2 (en) 2013-03-14 2016-09-06 Neuravi Limited Clot retrieval devices
WO2014201380A1 (en) 2013-06-14 2014-12-18 Altai Medical Technologies Inferior vena cava filter and retrieval systems
US10076399B2 (en) * 2013-09-13 2018-09-18 Covidien Lp Endovascular device engagement
US20150257782A1 (en) * 2014-03-14 2015-09-17 Michael Chaim Cohn Adjustable Catheter System
EP3142598B1 (en) 2014-05-16 2020-07-08 Veosource SA Implantable self-cleaning blood filters
JP6612854B2 (ja) * 2014-09-14 2019-11-27 エンボライン， インコーポレイテッド 塞栓保護を備えた導入シース
JP6601501B2 (ja) 2014-11-04 2019-11-13 ニプロ株式会社 海綿骨を圧縮するための長手方向膨張要素が内部に設けられたカテーテルデバイス
US10363054B2 (en) 2014-11-26 2019-07-30 Neuravi Limited Clot retrieval device for removing occlusive clot from a blood vessel
US10617435B2 (en) 2014-11-26 2020-04-14 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
US11253278B2 (en) 2014-11-26 2022-02-22 Neuravi Limited Clot retrieval system for removing occlusive clot from a blood vessel
US20160166372A1 (en) * 2014-12-12 2016-06-16 Avantec Vascular Corporation Ivc filter retrieval systems with interposed support members
US10278804B2 (en) 2014-12-12 2019-05-07 Avantec Vascular Corporation IVC filter retrieval systems with releasable capture feature
CN105796207B (zh) * 2014-12-30 2018-05-11 先健科技(深圳)有限公司 滤器及其制作方法
EP3639768A1 (en) 2018-10-16 2020-04-22 Anaconda Biomed, S.L. A device for extraction of thrombus from a blood vessel and a thrombectomy apparatus
ES2577288B8 (es) * 2015-01-13 2019-01-10 Anaconda Biomed S L Dispositivo para trombectomía
US11771446B2 (en) 2020-10-19 2023-10-03 Anaconda Biomed, S.L. Thrombectomy system and method of use
JP6942362B2 (ja) 2015-11-09 2021-09-29 ラディアクション リミテッド 放射線遮蔽装置およびその用途
CN108697497A (zh) * 2015-12-10 2018-10-23 阿万泰血管公司 Ivc过滤器回收系统鞘改进
JP2019503741A (ja) * 2015-12-16 2019-02-14 ラピッド メディカル リミテッド 管腔内装置
US10617509B2 (en) 2015-12-29 2020-04-14 Emboline, Inc. Multi-access intraprocedural embolic protection device
CN105662647B (zh) * 2016-02-19 2017-11-17 杭州启明医疗器械有限公司 血栓过滤器
CN105852933B (zh) * 2016-04-27 2019-07-26 中国人民解放军第二军医大学 一种编丝式输尿管结石阻挡取出器
KR102494176B1 (ko) * 2016-09-06 2023-02-02 뉴라비 리미티드 혈관으로부터 폐색 혈전을 제거하기 위한 혈전 회수 장치
US10874499B2 (en) 2016-12-22 2020-12-29 Avantec Vascular Corporation Systems, devices, and methods for retrieval systems having a tether
CN107440763B (zh) * 2017-08-16 2023-09-12 北京赛铂医药科技有限公司 一种血管近端保护器
CN107796898B (zh) * 2017-11-24 2023-05-30 云南省烟草质量监督检测站 一种可拆卸过滤装置的顶空瓶
WO2020006451A1 (en) 2018-06-29 2020-01-02 Avantec Vascular Corporation Systems and methods for implants and deployment devices
US11406416B2 (en) 2018-10-02 2022-08-09 Neuravi Limited Joint assembly for vasculature obstruction capture device
CN110893128A (zh) * 2018-11-21 2020-03-20 上海宏普医疗器械有限公司 一种拆卸式可回收腔静脉血栓过滤器
CN109717985A (zh) * 2018-12-29 2019-05-07 复旦大学附属金山医院 一种血栓过滤器械
US11534191B2 (en) 2019-01-11 2022-12-27 Anaconda Biomed, S.L. Loading device for loading a medical device into a catheter
CN113677296A (zh) 2019-02-13 2021-11-19 艾姆伯莱恩公司 具有整合的栓塞防护装置的导管
US11672661B2 (en) 2019-08-22 2023-06-13 Silara Medtech Inc. Annuloplasty systems and methods
US11712231B2 (en) 2019-10-29 2023-08-01 Neuravi Limited Proximal locking assembly design for dual stent mechanical thrombectomy device
US11517340B2 (en) 2019-12-03 2022-12-06 Neuravi Limited Stentriever devices for removing an occlusive clot from a vessel and methods thereof
CN110946674A (zh) * 2019-12-31 2020-04-03 川北医学院附属医院 一种升主动脉血栓过滤装置
US11730501B2 (en) 2020-04-17 2023-08-22 Neuravi Limited Floating clot retrieval device for removing clots from a blood vessel
US11717308B2 (en) 2020-04-17 2023-08-08 Neuravi Limited Clot retrieval device for removing heterogeneous clots from a blood vessel
US11871946B2 (en) 2020-04-17 2024-01-16 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
CN113729873A (zh) * 2020-05-27 2021-12-03 关芳 血液净化器
CN113813039A (zh) * 2020-06-18 2021-12-21 上海复拓知达医疗科技有限公司 组织切取器和微创介入手术器械
US11737771B2 (en) 2020-06-18 2023-08-29 Neuravi Limited Dual channel thrombectomy device
US11937836B2 (en) 2020-06-22 2024-03-26 Neuravi Limited Clot retrieval system with expandable clot engaging framework
US11395669B2 (en) 2020-06-23 2022-07-26 Neuravi Limited Clot retrieval device with flexible collapsible frame
US11439418B2 (en) 2020-06-23 2022-09-13 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
US11864781B2 (en) 2020-09-23 2024-01-09 Neuravi Limited Rotating frame thrombectomy device
US11937837B2 (en) 2020-12-29 2024-03-26 Neuravi Limited Fibrin rich / soft clot mechanical thrombectomy device
CN113134121B (zh) * 2021-05-17 2023-02-07 浙江省嘉善县第一人民医院 一种感染性腔隙冲洗引流组件
US11974764B2 (en) 2021-06-04 2024-05-07 Neuravi Limited Self-orienting rotating stentriever pinching cells
CN113520526B (zh) * 2021-07-10 2022-09-06 大连大学附属中山医院 一种股动脉血管穿刺溶栓防护装置
CN113520520B (zh) * 2021-07-22 2022-07-08 上海心玮医疗科技股份有限公司 一种全覆盖式取栓装置
CN114052830A (zh) * 2021-12-21 2022-02-18 启晨(上海)医疗器械有限公司 血栓清除装置
CN115317077B (zh) * 2022-10-13 2023-02-17 成都百瑞恒通医疗科技有限公司 一种取栓装置
CN116269548B (zh) * 2023-05-24 2023-08-04 泓欣科创(北京)科技有限公司 止血器、止血装置、止血方法及止血器成型方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1328808A (zh) * 2001-07-13 2002-01-02 周星 新型植入式血栓滤器
CN1515326A (zh) 2003-01-07 2004-07-28 星 周 可回收血管滤器
JP3660931B2 (ja) * 2003-09-22 2005-06-15 新 石丸 血栓塞栓捕獲装置
US20080103522A1 (en) * 2006-10-27 2008-05-01 Medtronic Vascular, Inc. Distal Protection Device for Filtering and Occlusion
CN201088640Y (zh) * 2007-10-22 2008-07-23 北京有色金属研究总院 一种下腔静脉滤器回收装置
US20110190806A1 (en) * 2008-06-19 2011-08-04 Angiodynamics, Inc. Thrombectomy catheter and a device comprising the same
US20120059356A1 (en) * 2010-09-07 2012-03-08 Di Palma Giorgio Device and method for removing material from a hollow anatomical structure
CN102973332A (zh) * 2012-11-23 2013-03-20 杭州启明医疗器械有限公司 血栓过滤器及其使用方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4611594A (en) * 1984-04-11 1986-09-16 Northwestern University Medical instrument for containment and removal of calculi
CA2194671A1 (en) * 1994-07-08 1996-01-25 Ev3 Inc. Method of forming medical devices; intravascular occlusion devices
US5662671A (en) * 1996-07-17 1997-09-02 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries
US6626903B2 (en) * 1997-07-24 2003-09-30 Rex Medical, L.P. Surgical biopsy device
US20020138094A1 (en) * 1999-02-12 2002-09-26 Thomas Borillo Vascular filter system
US8298257B2 (en) * 2000-06-29 2012-10-30 Concentric Medical, Inc. Systems, methods and devices for removing obstructions from a blood vessel
US6436121B1 (en) * 2001-04-30 2002-08-20 Paul H. Blom Removable blood filter
DE10242444A1 (de) * 2002-09-11 2004-04-01 pfm Produkte für die Medizin AG Extraktionsvorrichtung
US20050261705A1 (en) * 2004-05-21 2005-11-24 Gist Christopher W Device to remove kidney stones
US20050283166A1 (en) * 2004-06-17 2005-12-22 Secant Medical, Llc Expandible snare
US8109941B2 (en) * 2005-02-28 2012-02-07 Boston Scientific Scimed, Inc. Distal release retrieval assembly and related methods of use
US20090222035A1 (en) * 2006-03-27 2009-09-03 Tel Hashomer Medical Research Infrastructure And S Intraluminal Mass Collector
CN101143114B (zh) * 2006-09-14 2011-01-12 微创医疗器械(上海)有限公司 双层静脉滤器
CN201086640Y (zh) 2007-08-29 2008-07-16 陈泽兴 汽车防盗器改良结构
WO2009055782A1 (en) * 2007-10-26 2009-04-30 Possis Medical, Inc. Intravascular guidewire filter system for pulmonary embolism protection and embolism removal or maceration
US20090192485A1 (en) * 2008-01-28 2009-07-30 Heuser Richard R Snare device
US8758364B2 (en) * 2008-08-29 2014-06-24 Rapid Medical Ltd. Device and method for clot engagement and capture
WO2012081020A1 (en) * 2010-12-12 2012-06-21 Perflow Medical Ltd. Method and apparatus for occlusion retrieval
US8469970B2 (en) * 2011-07-11 2013-06-25 Great Aspirations Ltd. Apparatus for entrapping and extracting objects from body cavities
US9597171B2 (en) * 2012-09-11 2017-03-21 Covidien Lp Retrieval catheter with expandable tip

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1328808A (zh) * 2001-07-13 2002-01-02 周星 新型植入式血栓滤器
CN1515326A (zh) 2003-01-07 2004-07-28 星 周 可回收血管滤器
JP3660931B2 (ja) * 2003-09-22 2005-06-15 新 石丸 血栓塞栓捕獲装置
US20080103522A1 (en) * 2006-10-27 2008-05-01 Medtronic Vascular, Inc. Distal Protection Device for Filtering and Occlusion
CN201088640Y (zh) * 2007-10-22 2008-07-23 北京有色金属研究总院 一种下腔静脉滤器回收装置
US20110190806A1 (en) * 2008-06-19 2011-08-04 Angiodynamics, Inc. Thrombectomy catheter and a device comprising the same
US20120059356A1 (en) * 2010-09-07 2012-03-08 Di Palma Giorgio Device and method for removing material from a hollow anatomical structure
CN102973332A (zh) * 2012-11-23 2013-03-20 杭州启明医疗器械有限公司 血栓过滤器及其使用方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2923673A4

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115068064A (zh) * 2022-07-19 2022-09-20 深圳佰特微医疗科技有限公司 取栓装置

Also Published As

Publication number Publication date
JP6034507B2 (ja) 2016-11-30
US20150366650A1 (en) 2015-12-24
BR112015011796B1 (pt) 2021-06-15
ES2645489T3 (es) 2017-12-05
JP2015535447A (ja) 2015-12-14
CN102973332B (zh) 2015-01-21
CN102973332A (zh) 2013-03-20
EP2923673A1 (en) 2015-09-30
EP2923673A4 (en) 2016-05-11
US10687932B2 (en) 2020-06-23
EP2923673B1 (en) 2017-07-26
BR112015011796A2 (pt) 2017-07-11

Similar Documents

Publication Publication Date Title
WO2014079291A1 (zh) 血栓过滤器及其使用方法
US8945169B2 (en) Embolic protection device
JP2016523119A5 (zh)
US20120330346A1 (en) Integrated distal embolization protection apparatus for endo-luminal devices such as balloon, stent or tavi apparatus
US20070038242A1 (en) Emboli filter
JP2012516709A (ja) 予め装填されたステント移植片の給送器具
JP2016523119A (ja) 血栓除去および脈管内遠位塞栓保護デバイス
KR101238990B1 (ko) 임플란트 회수 장치 및 그를 이용한 임플란트 제거 방법
CA2436707A1 (en) Endovascular guidewire filter and methods of use
CN108577930B (zh) 带有球囊的杯状取石网篮
CN103385744A (zh) 具有远端保护器的临时滤器
CN212307969U (zh) 一种一体式取栓支架
CN210903224U (zh) 血栓整体清除装置
CN107126298A (zh) 可回收式主动脉临时栓塞保护装置
CN117257514A (zh) 抗血栓保护装置及医疗器械
CN108420487A (zh) 一种可视可控的腔道内支架的钩挂回收装置
CN212326510U (zh) 血栓剥离导管
CN213189936U (zh) 一种经胆道镜取石装置
CN116831678B (zh) 一种便于推送的动脉瘤扰流装置
CN207605039U (zh) 可回收式主动脉临时栓塞保护装置
CN116019527A (zh) 一种带保护伞的鞘管
CN209361004U (zh) 一种用于胆管及胰腺的爪形支架取出器械
CN217244652U (zh) 一种血栓剥离收集网兜及静脉取栓装置
CN215228144U (zh) 一种取栓装置
WO2024093558A1 (zh) 取栓装置、血栓治疗装置及其使用方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13856435

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2015543265

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2013856435

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2013856435

Country of ref document: EP

REG Reference to national code

Ref country code: BR

Ref legal event code: B01A

Ref document number: 112015011796

Country of ref document: BR

WWE Wipo information: entry into national phase

Ref document number: 14646091

Country of ref document: US

ENP Entry into the national phase

Ref document number: 112015011796

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20150521