WO2014045677A1 - Aiguille de biopsie et système de biopsie - Google Patents

Aiguille de biopsie et système de biopsie Download PDF

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Publication number
WO2014045677A1
WO2014045677A1 PCT/JP2013/068498 JP2013068498W WO2014045677A1 WO 2014045677 A1 WO2014045677 A1 WO 2014045677A1 JP 2013068498 W JP2013068498 W JP 2013068498W WO 2014045677 A1 WO2014045677 A1 WO 2014045677A1
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WO
WIPO (PCT)
Prior art keywords
needle
ultrasonic
needle tube
biopsy
acoustic impedance
Prior art date
Application number
PCT/JP2013/068498
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English (en)
Japanese (ja)
Inventor
鈴木　啓太
Original Assignee
オリンパスメディカルシステムズ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オリンパスメディカルシステムズ株式会社 filed Critical オリンパスメディカルシステムズ株式会社
Publication of WO2014045677A1 publication Critical patent/WO2014045677A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/04—Endoscopic instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/04—Endoscopic instruments
    • A61B2010/045—Needles

Definitions

  • the present invention relates to a biopsy needle for collecting body tissue, and more particularly to a biopsy needle used under observation by an ultrasound image, and a biopsy system using the biopsy needle.
  • Patent Document 1 describes a biopsy needle used for such an application.
  • the biopsy needle is provided with a plurality of annular grooves on the outer peripheral surface so that the ultrasonic wave emitted from the ultrasonic probe of the ultrasonic endoscope can be preferably reflected toward the ultrasonic probe. The visibility of the biopsy needle is improved by returning more ultrasonic waves to the ultrasonic probe by the annular groove.
  • the present invention has been made in view of the above-described problems, and provides a biopsy needle that can stabilize an image in an image of an ultrasonic observation section by uniformizing the ultrasonic reflection mode. With the goal.
  • the biopsy needle according to the first aspect of the present invention is formed hollow using a first material, has a needle body having a reflection groove on the outer peripheral surface, and a first of the first material in the reflection groove.
  • a contact auxiliary layer formed using a second material having a second acoustic impedance different from the acoustic impedance.
  • the second acoustic impedance is substantially equal to a third acoustic impedance of a tissue into which the needle body is inserted. Good.
  • a biopsy system includes the biopsy needle of the first aspect and an endoscope having a probe that emits ultrasonic waves, and the second acoustic impedance is the third acoustic impedance.
  • the thickness of the auxiliary contact layer is an integral multiple of one half of the wavelength of the ultrasonic wave emitted from the probe.
  • the ultrasonic wave reflection mode at the portion where the concave portion is provided on the outer peripheral surface of the needle tube is made uniform, and the ultrasonic wave is more reliably reflected to the ultrasonic scanning mechanism, and the ultrasonic observation unit It is possible to provide a biopsy needle that can stabilize the image of the needle tube in the above image.
  • FIG. 3 is a cross-sectional view taken along line AA in FIG. 2.
  • FIG. 3 is a cross-sectional view taken along line BB in FIG. 2. It is a half sectional view showing the vicinity of the sheath adjuster in the operation part of the treatment instrument.
  • the biopsy needle of the present embodiment is used by being inserted into a channel of an ultrasonic endoscope so as to be able to advance and retreat, and attached to a treatment instrument for performing treatment in the body together with the ultrasonic endoscope.
  • FIG. 1 is a perspective view illustrating a schematic configuration of a biopsy system 150 including the treatment tool 1 and the ultrasonic endoscope 100 according to the present embodiment.
  • the ultrasonic endoscope 100 includes an insertion portion 101 inserted into the body from the distal end, an operation portion 109 attached to the proximal end of the insertion portion 101, and one end on the side of the operation portion 109.
  • Universal cord 112 to which (first end) is connected; light source device 113 connected to the other end (second end) of universal cord 112 via branch cable 112a; branch cable 112b to the other end of universal cord 112 And an ultrasonic observation unit 115 connected to the other end of the universal cord 112 via a branch cable 112c.
  • the insertion portion 101 includes a distal end hard portion 102, a bending portion 105, and a flexible tube portion 106, which are arranged in this order from the distal end side.
  • the distal end hard portion 102 includes an optical imaging mechanism 103 for performing optical observation and an ultrasonic scanning mechanism 104 for performing ultrasonic observation.
  • the optical imaging mechanism 103 is an imaging optical system whose field of view is directed diagonally forward of the hard tip portion 102, an image sensor such as a CCD or CMOS that detects an image of a subject incident through the imaging optical system, and the operation of the image sensor.
  • image sensor such as a CCD or CMOS that detects an image of a subject incident through the imaging optical system
  • Various components such as a CPU to be controlled are provided.
  • the ultrasonic scanning mechanism (probe) 104 includes an ultrasonic transducer (not shown) that emits and receives ultrasonic waves.
  • the ultrasonic scanning mechanism 104 receives the reflected wave reflected by the ultrasonic wave emitted from the ultrasonic vibrator when it hits the observation target, and observes the signal based on the ultrasonic wave received by the ultrasonic vibrator. Output to the unit 115.
  • the bending portion 105 is formed in a cylindrical shape. By pulling an angle wire (not shown) fixed to the distal end of the bending portion 105 and extending to the operation portion 109 in the operation portion 109, the bending portion 105 bends in a predetermined direction such as four directions of up, down, left, and right.
  • the flexible tube portion 106 is a cylindrical member that is formed flexibly so that the distal end hard portion 102 can be guided to a desired position in the digestive tract and the body cavity.
  • a cylindrical channel 107 for inserting the treatment instrument 1 and a conduit (not shown) for performing air supply / water supply and suction are provided inside each of the bending portion 105 and the flexible tube portion 106.
  • One end (first end) of the channel 107 is opened in the vicinity of the distal end portion of the distal end hard portion 102, and the other end (second end) of the channel 107 is opened on the side surface on the distal end side of the operation portion 109.
  • a base end cap 108 formed in a flange shape is fixed to the other end of the channel 107.
  • the treatment tool 1 used together with the ultrasonic endoscope 100 can be fixed to the proximal end cap 108.
  • the operation unit 109 has an outer surface formed so that a user who uses the ultrasonic endoscope 100 can hold in the hand, and a bending operation mechanism for bending the bending unit 105 by pulling the angle wire. 110 and a plurality of switches 111 for supplying air, supplying water, or sucking through a pipe line.
  • the light source device 113 is a device for emitting illumination light for imaging by the optical imaging mechanism 103.
  • the optical observation unit 114 is configured to display a video image captured by the image sensor of the optical imaging mechanism 103 on the monitor 116.
  • the ultrasonic observation unit 115 receives the signal output from the ultrasonic scanning mechanism 104, generates an image based on this signal, and displays the image on the monitor 116.
  • FIG. 2 is a side view showing the treatment instrument 1 in a partial sectional view.
  • FIG. 3 is a diagram showing the configuration of the distal end side of the insert 2 and is a cross-sectional view along the axial direction of the insert 2.
  • the treatment instrument 1 includes an insertion body 2, an operation unit 8, and a stylet 27.
  • the insert 2 includes a cylindrical needle tube (biopsy needle) 3 having a distal end and a proximal end, and a cylindrical sheath 7 into which the needle tube 3 is inserted.
  • the material of the needle tube 3 is preferably a material that has flexibility and elasticity that can be easily restored to a linear state even when bent by an external force.
  • a material (first material) of the needle tube 3 an alloy material such as a stainless alloy, a nickel titanium alloy, and a cobalt chromium alloy can be employed as a material (first material) of the needle tube 3.
  • FIG. 4 is an enlarged plan view of the distal end portion of the needle tube 3
  • FIG. 5 is an enlarged sectional view of the distal end portion.
  • the opening 31 provided at the distal end of the needle tube 3 is formed by cutting off the distal end of the tubular member forming the needle tube obliquely at one or more planes with respect to the axis of the tubular member so that it can be inserted into a living tissue. It is sharply formed.
  • the specific shape of the opening 31 may be appropriately selected from various known shapes in consideration of the target tissue and the like.
  • a plurality of minute recesses (reflection grooves) 32 are provided on the outer peripheral surface of the needle tube 3 in order to improve reflection characteristics with respect to ultrasonic waves.
  • the recesses 32 are formed on the outer peripheral surface of the needle tube 3 at substantially equal intervals in the circumferential direction, and are formed so that the phase in the circumferential direction is different from the recesses adjacent in the longitudinal direction of the needle tube 3. .
  • positioning aspect is an example and the arrangement
  • the recess 32 in the present embodiment is formed in an annular shape, and the recess 32 is disposed by being filled with a second material 33.
  • the acoustic impedance (second acoustic impedance) of the second material 33 is different from the acoustic impedance (first acoustic impedance) of the material (first material) of the needle tube 3.
  • the recess 32 is filled with the second material 33, and the contact auxiliary layer 35 made of the second material 33 is formed on the recess 32 on the outer peripheral surface of the needle tube 3.
  • the second material 33 preferably has an acoustic impedance lower than that of the needle tube 3 material (first material), and further has an acoustic impedance equivalent to the acoustic impedance of the tissue to be biopsied.
  • first material the needle tube 3 material
  • second material the second material because the hardness is lower than that of the metal used as the first material and the acoustic impedance is closer to the body tissue.
  • the sheath 7 has a flexible tubular member such as a metal coil or resin, and extends from the distal end of the operation unit 8.
  • the resin that can be used as the material of the sheath 7 include polyether ether ketone (PEEK), fluorine resin, olefin resin, urethane resin, and nylon (polyamide) resin.
  • PEEK polyether ether ketone
  • fluorine resin fluorine resin
  • olefin resin olefin resin
  • urethane resin urethane resin
  • nylon (polyamide) resin nylon (polyamide) resin.
  • the operation unit 8 includes an operation main body 9, a sheath adjuster 18 provided on the distal end side of the operation main body 9, and a needle slider 23 provided on the proximal end side of the operation main body 9.
  • the operation body 9 includes a sheath slider 10 for adjusting the protruding length of the sheath 7, a slide rail 13 extending from the sheath slider 10 toward the proximal end side of the operation portion 8, and a slider stopper 14 provided on the slide rail 13.
  • FIG. 6 is a cross-sectional view taken along line AA in FIG.
  • the sheath slider 10 is formed in a substantially cylindrical shape, and penetrates in the thickness direction of the sheath slider 10 to attach a screw 11 for fixing the sheath adjuster 18 to the outer surface thereof.
  • a screw hole 10a is formed.
  • a pair of protrusions 10b and 10c are formed inside the sheath slider 10 so as to fit into a groove of a slide rail 22 described later of the sheath adjuster 18.
  • the tip of the screw 11 can abut on the outer surface of a slide rail 22 to be described later, and a large-diameter portion 12 having a larger diameter than the shaft is provided on the head. Further, a plurality of grooves are formed on the outer periphery of the large diameter portion 12. Thereby, the screw 11 can be easily turned by hand.
  • FIG. 7 is a cross-sectional view taken along line BB in FIG.
  • the slide rail 13 is a substantially cylindrical member for moving the needle slider 23 back and forth in the direction of the central axis, and a groove 13a extending parallel to the central axis is formed on the outer surface.
  • a groove 13b is formed.
  • the groove 13a and the groove 13b are respectively disposed at positions facing the slide rail 13 in the radial direction.
  • thread 16 mentioned later among the outer peripheral surfaces of the slide rail 13 is formed flat.
  • the slider stopper 14 has a ring member 15 in which a screw hole 15 a penetrating in the thickness direction is formed and the slide rail 13 is inserted therein, and a screw 16 screwed into the screw hole 15 a of the ring member 15.
  • the ring member 15 has an inner diameter slightly larger than the diameter of the slide rail 13, and is attached to the slide rail 13 so as to be able to advance and retract in the direction of the central axis of the slide rail 13.
  • the ring member 15 is formed with protrusions 15 b and 15 c inserted into the groove 13 a and the groove 13 b, and the ring member 15 does not rotate in the circumferential direction of the slide rail 13.
  • the tip of the screw 16 can contact the outer peripheral surface of the slide rail 13, and the ring member 15 can be fixed to the slide rail 13 by screwing the screw 16 into the screw hole 15 a of the ring member 15.
  • a large diameter portion 17 having a large diameter is provided at the base end of the screw 16, and a plurality of grooves are formed on the outer periphery of the large diameter portion 17. Thereby, the screw 16 can be easily turned by hand.
  • FIG. 8 is a half sectional view showing the vicinity of the sheath adjuster 18 in the operation unit 8.
  • the sheath adjuster 18 is provided to adjust the amount of projection of the sheath 7 from the tip of the channel 107 of the ultrasonic endoscope 100 as shown in FIG.
  • the sheath adjuster 18 includes a fixed screw portion 19 fixed to the proximal end cap 108 of the ultrasonic endoscope 100 and a slide fixed to the fixed screw portion 19 and inserted into the sheath slider 10. Rail 22.
  • the fixing screw portion 19 is formed with a through hole 20 through which the sheath 7 is inserted and a screw groove 21 for attaching the fixing screw portion 19 to the base end cap 108. Further, on the outer peripheral surface of the fixing screw portion 19, an unevenness functioning as a slip stopper is formed when the fixing screw portion 19 is attached to the base end base 108 or the fixing screw portion 19 is removed from the base end base 108. .
  • the slide rail 22 is a cylindrical member in which a pair of grooves extending in parallel with the central axis is formed, and the sheath 7 and the needle tube 3 are inserted therein.
  • the front end of the slide rail 22 is fixed to the fixing screw portion 19, and the slide rail 22 is inserted into the sheath slider 10.
  • a protrusion 10b formed on the sheath slider 10 is fitted into the groove 22ab.
  • a protrusion 10c formed on the sheath slider 10 is fitted in the groove 22b.
  • the tip end of the screw 11 screwed into the screw hole 10 a of the sheath slider 10 can come into contact with the outer surface of the slide rail 22.
  • the slide rail 22 and the sheath slider 10 are fixed by pressing the tip of the screw 11 against the outer surface of the slide rail 22.
  • the slide rail 22 of the sheath adjuster 18 and the sheath slider 10 can move relative to each other along the longitudinal direction of the groove.
  • FIG. 9 is an enlarged half sectional view showing the needle slider 23 in the operation unit 8.
  • FIG. 10 is an enlarged view of the needle slider 23 in the operation unit 8, and is a view taken in the direction of arrow C in FIG.
  • the needle slider 23 is a cylindrical member into which the slide rail 13 of the operation main body 9 is inserted, and a pair of protrusions 23 a (two protrusions) that fit into the grooves 13 a and 13 b of the slide rail 13. One of the 23a is not shown).
  • the distal end of the needle slider 23 can come into contact with the proximal end of the slider stopper 14.
  • a screw thread 23c for screwing a knob 28 and a syringe 120, which will be described later, is formed at the proximal end of the needle slider 23.
  • the outer surface shape of the needle slider 23 is a cylindrical surface so that a user using the treatment instrument 1 can hold it. Further, as shown in FIG. 10, a gauge number display section 24 is formed on the outer surface of the needle slider 23, in which a gauge number indicating the diameter of the needle tube 3 is displayed by engraving or the like.
  • the proximal end of the needle tube 3 is fixed inside the needle slider 23.
  • a stylet 27 described later can be inserted from the proximal end of the needle tube 3 fixed to the needle slider 23.
  • the needle slider 23 By moving the needle slider 23 in the direction of the central axis along the grooves 13a and 13b (see FIG. 7) of the slide rail 13, the needle tube 3 can protrude and retract from the sheath 7.
  • the needle slider 23 and the slide rail 13 are coupled so that the needle slider 23 and the slide rail 13 are not detached when the needle slider 23 is moved to the proximal end side of the slide rail 13.
  • the distal end of the needle tube 3 fixed to the needle slider 23 is drawn into the distal end of the sheath 7 and is covered by the sheath 7. It is in.
  • FIG. 11A is a side view of the stylet 27. 12 is a cross-sectional view taken along the line DD of FIG. 11A.
  • the stylet 27 is a metal wire, and can be inserted into the needle tube 3 so as to advance and retract. That is, the outer diameter of the stylet 27 is smaller than the inner diameter of the needle tube 3.
  • the tip of the stylet 27 is sharply formed, and a knob 28 made of resin or the like is provided at the base end of the stylet 27.
  • the tip of the stylet 27A may be formed in a substantially hemispherical shape.
  • the knob 28 provided at the base end of the stylet 27 is formed with a gauge number display portion 29 in which the gauge number of the needle tube 3 into which the stylet 27 can be suitably inserted is displayed by engraving or the like. That is, if the stylet 27 has the same numerical value as the gauge number displayed on the gauge number display section 24 provided on the needle slider 23 displayed on the knob 28, the stylet 27 is preferably inserted into the needle tube 3. Can be used. Thereby, the mistake in the case of using the some treatment tool 1 from which the diameter of the needle tube 3 and the stylet 27 differs can be avoided by one procedure.
  • the knob 28 is formed with a thread groove 28 a that fits into a thread 23 c (see FIG. 9) formed at the proximal end of the needle slider 23.
  • the stylet 27 can be fixed to the needle slider 23 by screwing the screw groove 28 a of the knob 28 with the screw thread 23 c of the needle slider 23.
  • the tip of the stylet 27 is set so as to slightly protrude from the tip of the needle tube 3 (see FIG. 3).
  • FIG. 13 to FIG. 18 are operation explanatory views for explaining the operation at the time of using the treatment instrument 1.
  • a biopsy in which the needle tube 3 of the treatment instrument 1 is inserted into a tissue such as a lesion located in the deep part of the body tissue and the cells of the lesion are collected through the inside of the needle tube 3. This will be described as an example.
  • the user inserts the insertion portion 101 of the ultrasonic endoscope 100 into the body, and optically observes a site to be treated using the optical imaging mechanism 103. Further, the ultrasonic scanning mechanism 104 can be used to observe the deep part of the site to be treated.
  • a part to be biopsied is determined.
  • the user inserts the insertion body 2 of the treatment instrument 1 from the distal end side into the channel 107 from the proximal end cap 108 provided in the operation unit 109 of the ultrasonic endoscope 100. Further, the user fixes the fixing screw portion 19 provided in the operation unit 8 of the treatment instrument 1 to the base end cap 108. Thereby, the treatment tool 1 is fixed to the ultrasonic endoscope 100.
  • the user loosens the screw 11 provided on the sheath slider 10 and observes the sheath 7 and the body by the optical imaging mechanism 103 and the ultrasonic scanning mechanism 104 while using the sheath adjuster 18 to set the ultrasonic endoscope 100.
  • the amount of protrusion of the sheath 7 from the distal end of the insertion portion 101 is adjusted to an appropriate amount.
  • the slider stopper 14 is moved according to the position of the target tissue T to be biopsied and fixed to the slide rail 13. As a result, the maximum length by which the needle tube 3 can protrude from the sheath 7 is limited to the length until the needle slider 23 comes into contact with the slider stopper 14.
  • the user pushes the needle slider 23 toward the distal end side of the operation unit 8. Then, the needle tube 3 protrudes from the sheath 7 as shown in FIG. Further, as shown in FIG. 16, the distal end of the needle tube 3 is punctured into the tissue and pushed forward to the target tissue T to be biopsied. At this time, the needle tube 3 exposed to the outside from the surface of the tissue can be observed by the optical imaging mechanism 103, and the tip side portion of the needle tube 3 inserted into the tissue is observed by the ultrasonic scanning mechanism 104. Can do.
  • FIG. 17 is an enlarged view showing a cross section of the needle tube 3 in the tissue.
  • the outer peripheral surface of the needle tube 3 has an angle at which it is difficult to reflect the ultrasonic wave emitted from the ultrasonic scanning mechanism 104 toward the ultrasonic operation mechanism 104, but one of the inner surfaces of the recesses 32 formed on the outer peripheral surface.
  • the unit has an angle at which the ultrasonic wave emitted from the ultrasonic scanning mechanism 104 is easily reflected toward the ultrasonic operation mechanism 104. As a result, the number of ultrasonic waves received by the ultrasonic scanning mechanism 104 increases, and the tip of the needle tube 3 is clearly projected on the ultrasonic observation unit 115.
  • the contact assisting layer 35 is formed on the concave portion 32, air hardly remains in the concave portion 32 when the needle tube 3 is inserted into the tissue, and there is no gap between the needle tube 3 and the tissue.
  • the contact assisting layer 35 secures a suitable contact state.
  • the user can observe an ultrasonic image based on the ultrasonic wave received by the ultrasonic scanning mechanism 104 with the ultrasonic observation unit 115 shown in FIG.
  • the user causes the tip of the needle tube 3 to reach the target tissue T on which biopsy is performed. Note that when the tip of the needle tube 3 reaches the target tissue T to be biopsied, the stylet 27 is inserted into the needle tube 3, so that the tissue does not enter the needle tube 3.
  • the user turns the knob 28 of the stylet 27 shown in FIG. 2 to remove the knob 28 from the needle slider 23, and pulls out the stylet 27 from the insert 2 and the operation unit 8.
  • a through hole extending from the distal end of the needle tube 3 to the proximal end of the needle slider 23 is generated.
  • the user fixes an appropriate syringe 120 having a distal end fitted to a thread 23 c formed at the proximal end of the needle slider 23 to the thread 23 c.
  • the inside of the needle tube 3 is sucked by the syringe 120, and the cells of the target tissue T to be biopsied from the tip of the needle tube 3 are sucked into the syringe 120.
  • the needle slider 23 When a necessary amount of cells and the like are sucked into the syringe 120, the needle slider 23 is pulled to the base end side of the operation unit 8 to the full, and the distal end of the needle tube 3 is accommodated in the sheath 7. Thereby, the needle tube 3 comes out of the tissue.
  • the fixing screw portion 19 is removed from the base end cap 108 of the operation portion 109 of the ultrasonic endoscope 100, and the treatment tool 1 is removed from the channel 107. The series of treatments is thus completed.
  • the contact auxiliary layer 35 made of the second material 33 is provided on the plurality of recesses 32 and the recesses 32 are filled, air does not remain in the recesses 32.
  • the above-described variation in the state of the boundary between the recess and the tissue can be suppressed.
  • the reflection mode of the ultrasonic wave at the portion where the concave portion 32 is provided on the outer peripheral surface of the needle tube 3 is made uniform, and the ultrasonic wave is more reliably reflected to the ultrasonic scanning mechanism 104, so The image of the needle tube 3 can be stabilized.
  • the second material 33 forming the contact assisting layer 35 has an acoustic impedance different from that of the first material forming the needle tube 3, the recess 32 serving as an interface between the first material and the second material is formed. Ultrasonic reflection preferably occurs on the inner surface. Therefore, it is possible to reliably return ultrasonic waves to the ultrasonic scanning mechanism 104 according to the inner surface shape of the recess 32.
  • the second material has an acoustic impedance equivalent to that of the tissue into which the needle tube 3 is inserted, reflection of ultrasonic waves at the interface between the second material and the tissue can be suppressed.
  • the ultrasonic wave is reflected at the interface between the second material and the tissue, it is reflected in a direction substantially equivalent to that reflected by the outer peripheral surface of the needle tube, so that it is difficult to contribute to the improvement of the visibility in the ultrasonic image. Therefore, the second material preferably has an acoustic impedance as close as possible to the tissue into which the needle tube is inserted.
  • the shape of the reflection groove of the contact auxiliary layer is not limited to the above-described ring shape.
  • a groove 32a having a circular shape on the outer peripheral surface and having a predetermined depth may be used.
  • a groove 32b extending in the circumferential direction of the needle tube 3 is formed in the longitudinal direction of the needle tube 3.
  • a plurality may be formed at intervals in the direction.
  • 19A and 19B show enlarged cross-sectional shapes of the grooves 32a and 32b, respectively.
  • FIGS. 1 and 2 The difference between the biopsy needle of the present embodiment and the biopsy needle of the first embodiment is the arrangement of the second material in the contact auxiliary layer.
  • components that are the same as those already described are assigned the same reference numerals and redundant description is omitted.
  • FIG. 20 is an enlarged view showing a cross section of the distal end portion of the needle tube 50 of the present embodiment.
  • the concave portion 52 provided on the outer peripheral surface of the needle tube 50 has a spherical inner surface
  • the second material 53 forming the contact assisting layer 55 has a predetermined thickness t on the inner surface of the concave portion 52.
  • t a dimension in a direction orthogonal to a tangent line that contacts the inner surface at this position.
  • the predetermined thickness t is an integral multiple of one half of the wavelength of the ultrasonic wave emitted from the ultrasonic scanning mechanism 104. That is, when the wavelength of the emitted ultrasonic wave is 1, the thickness t can be expressed by n / 2 ⁇ l (where n is a natural number).
  • the acoustic impedance of the second material 53 is different from that of the first material, and is also different from the acoustic impedance of the tissue into which the needle tube 50 is inserted (third acoustic impedance).
  • the ultrasonic wave emitted from the ultrasonic scanning mechanism 104 is transmitted between the tissue and the contact auxiliary layer as shown in FIG. Reflected at the interface with 55 and the interface between the contact auxiliary layer and the recess 52. Then, when the ultrasonic wave enters perpendicularly to the inner surface of the concave portion 52, the path between the ultrasonic wave reflected at the interface between the tissue and the contact auxiliary layer 55 and the ultrasonic wave reflected at the interface between the contact auxiliary layer and the concave portion 52.
  • the shape of the inner surface of the concave portion is not limited to this, and may include a flat portion such as the concave portion 57 shown in FIG. Even in such a case, the same effect can be obtained by setting the thickness t of the contact auxiliary layer 55 to a value that is uniform and an integral multiple of one half of the wavelength of the ultrasonic wave.
  • the ultrasonic reflection mode at the site where the concave portion is provided on the outer peripheral surface of the needle tube is made uniform, and the ultrasonic wave is more reliably reflected to the ultrasonic scanning mechanism, so that the ultrasonic observation is performed. It is possible to provide a biopsy needle that can stabilize the image of the needle tube in the image of the part.

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Abstract

La présente invention concerne une aiguille de biopsie qui est dotée d'un corps d'aiguille principal qui est formé avec un centre creux en utilisant un premier matériau et qui a un sillon réfléchissant sur la surface de la circonférence externe, et avec une couche auxiliaire de contact qui est formée dans le sillon réfléchissant en utilisant un second matériau ayant une seconde impédance acoustique différente de la première impédance acoustique du premier matériau.
PCT/JP2013/068498 2012-09-21 2013-07-05 Aiguille de biopsie et système de biopsie WO2014045677A1 (fr)

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US201261703955P 2012-09-21 2012-09-21
US61/703,955 2012-09-21

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107343812A (zh) * 2016-05-05 2017-11-14 上海安久生物科技有限公司 超声引导穿刺针和制备方法
EP3260050A4 (fr) * 2015-02-19 2018-11-14 Olympus Corporation Aiguille de biopsie
WO2023040471A1 (fr) * 2021-09-14 2023-03-23 贝普医疗科技股份有限公司 Aiguille pour bloc nerveux guidée par ultrasons

Citations (4)

* Cited by examiner, † Cited by third party
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JPH08206118A (ja) * 1994-04-14 1996-08-13 Yasuo Majima 医療用穿刺針
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JP2006271874A (ja) * 2005-03-30 2006-10-12 Toshiba Corp 超音波ガイド下穿刺針
WO2007013130A1 (fr) * 2005-07-25 2007-02-01 Hakko Co., Ltd. Aiguille de perçage à ultrasons
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EP3260050A4 (fr) * 2015-02-19 2018-11-14 Olympus Corporation Aiguille de biopsie
CN107343812A (zh) * 2016-05-05 2017-11-14 上海安久生物科技有限公司 超声引导穿刺针和制备方法
WO2023040471A1 (fr) * 2021-09-14 2023-03-23 贝普医疗科技股份有限公司 Aiguille pour bloc nerveux guidée par ultrasons

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