WO2014029035A1 - Mischvorrichtung für eine austrageinheit - Google Patents
Mischvorrichtung für eine austrageinheit Download PDFInfo
- Publication number
- WO2014029035A1 WO2014029035A1 PCT/CH2013/000121 CH2013000121W WO2014029035A1 WO 2014029035 A1 WO2014029035 A1 WO 2014029035A1 CH 2013000121 W CH2013000121 W CH 2013000121W WO 2014029035 A1 WO2014029035 A1 WO 2014029035A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mixing
- mixing device
- channels
- discharge unit
- substances
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/7174—Feed mechanisms characterised by the means for feeding the components to the mixer using pistons, plungers or syringes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00593—Hand tools of the syringe type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/432—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
- B01F25/4323—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa using elements provided with a plurality of channels or using a plurality of tubes which can either be placed between common spaces or collectors
- B01F25/43231—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa using elements provided with a plurality of channels or using a plurality of tubes which can either be placed between common spaces or collectors the channels or tubes crossing each other several times
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/434—Mixing tubes comprising cylindrical or conical inserts provided with grooves or protrusions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/44—Mixers in which the components are pressed through slits
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/50—Movable or transportable mixing devices or plants
- B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
- B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
- B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00553—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes with means allowing the stock of material to consist of at least two different components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
- A61B2017/00495—Surgical glue applicators for two-component glue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F2025/91—Direction of flow or arrangement of feed and discharge openings
- B01F2025/915—Reverse flow, i.e. flow changing substantially 180° in direction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C17/00—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces
- B05C17/005—Hand tools or apparatus using hand held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material from a reservoir or container located in or on the hand tool through an outlet orifice by pressure without using surface contacting members like pads or brushes
- B05C17/00503—Details of the outlet element
Definitions
- the present invention relates to a mixing device which is attachable to a discharge inlet, and which serves in the discharge of one or more substances from the Austringeinlieit for mixing these substances.
- the mixing device is a static mixer.
- the invention also relates to a set comprising a discharge unit and such a mixing device.
- PRIOR ART Mixing devices and in particular so-called static mixers, are often used in medical but also in other applications in order to mix two or more substances together on discharge from a discharge unit.
- the substances to be mixed together are usually stored in a discharge unit with separate reservoirs, such as a double or multiple syringe.
- a discharge unit with separate reservoirs, such as a double or multiple syringe.
- the substances are then mixed within the mixing device connected to the Austringeinlieit to a homogeneous mixture as possible.
- flow-influencing elements are usually provided for this, which cause turbulence in the fluid flow, thereby achieving a mixing of the substances.
- Such mixing devices can also serve to a single substance stored in a Austringeinlieit substance composition, temperature or Homogenize density differences.
- the mixing device should also have a compact design and be as simple and inexpensive to produce.
- a mixing device is proposed, as indicated in claim 1.
- a set is specified in claim 14, which has such a mixing device and a discharge unit.
- the present invention thus provides a mixing device which can be connected to a discharge unit and which serves to mix these substances when discharging one or more substances from the discharge unit.
- the mixing device has a base element with a circumferential side wall and an insert part, which can be inserted into the base element in such a way that it bears sealingly against the side wall of the base element with at least one circumferential area.
- On the insert part a mixing structure with mixing channels is formed, through which the substances can be discharged from the discharge unit.
- Such a configuration of the mixing device makes it possible, in particular, to mix low-viscosity substances optimally with each other even at low volumes within the mixed structure with a minimum loss volume. Due to the fact that the mixing device has a base element and an insert part which can be inserted therein, the mixing device is very cost-effective and, in particular, compact.
- the distal direction refers in each case to that direction in which the substances are carried out as intended along a main flow direction out of the discharge unit and through the mixing device.
- the proximal direction extends in the opposite direction.
- the insert part as a whole has a substantially cylindrical shape.
- the base element preferably has a substantially hollow cylindrical shape with an advantageously continuously tapering at least slightly in the distal direction Inner radius on.
- the mixing channels of the mixing structure generally have a clearly defined configuration, which means that the fluid flow in the mixing channels is guided in each case in clearly defined paths.
- the mixing channels preferably each form tubular or tubular structures, which means that the individual mixing channels each have a certain length, which is unbranched and is not cut by other mixing channels.
- the peripheral region with which the insert member sealingly abuts the side wall of the base member constitutes a major part of the entire peripheral portion of the insert member.
- the insert member is thus at least 50%, more preferably at least 70%, and most preferably at least 90% %, along its circumference, sealingly against the side wall of the base element.
- the discharge unit may in particular be a double or multiple syringe, in which different substances which are to be mixed with one another during the discharge are stored in different reservoirs.
- the substances can also be stored in the reservoirs of different individual syringes, which can be connected to one another, in particular in the region of the proximal pressure surfaces of their pistons.
- the distal outlet openings of the individual syringes can also be connected to one another, for example, by means of a connection part, which merges the outlet openings into a common connection for the mixing device.
- the discharge unit can also be a single individual syringe, in which the substances are already stored in a common reservoir, for example, but are not yet sufficiently mixed with one another.
- it may also be a discharge unit with a single substance, which is to be homogenized during discharge, for example, in terms of density or temperature.
- the mixing device can be accommodated in different connecting elements and in particular can be designed as a spray head, a cannula or a catheter.
- the mixing structure is formed laterally in the peripheral region of the insert part.
- the mixing structure is then thus formed with their mixing channels in the outer side of the insert part, wherein the mixing channels are formed in particular outwardly open. Together with the peripheral side wall of the base member, the insert then limits the mixing channels.
- the preparation of the mixing device can be carried out in such an embodiment, in particular very simple and inexpensive, by the milled structure, for example, simply milled on the outside of the insert or provided accordingly in an injection mold.
- the mixing structure extends in the distal direction over the entire length of the insert part.
- the mixing structure is formed by depressions in the outer wall of the insert part and in particular designed groove-shaped.
- the mixing channels are then formed by recesses or grooves, which are formed on the outside of the insert part.
- the mixing structure preferably has a maximum depth, which is not greater than half, more preferably a third, of the radius of the insert part, if this is designed substantially cylindrical. In this way, the loss volume of the mixing device can be kept very small in particular.
- the mixing structure has at least one pair of two channels extending separately from one another and a mixing zone into which the two channels running separately from one another open. By means of these two channels running separately from one another, the fluid flow is thus guided, in particular, into a mixing zone in such a way that a turbulent flow is created therein, which leads to a mixing of the substances.
- the two separate channels advantageously extend both in the main flow direction and in the direction opposite to the main flow direction.
- the mixing channels thus preferably have sections. which are flowed through by the fluid flow substantially in the main flow direction, ie in the distal direction, as well as portions which from the fluid flow substantially in the through the direction of the main flow direction, ie in the proximal direction, are flowed through.
- the two channels extending separately from one another open advantageously into the mixing zone in such a way that the substances pass from one another into the mixing zone in substantially opposite directions.
- the fluid streams may each be slightly inclined in entering the mixing zone in the Hauptllussraum.
- the separate channels thus advantageously open from essentially opposite directions into the mixing zone.
- the two channels which run separately from one another, even open into the mixing zone in such a way that the substances, projected onto the main flow direction, respectively reach the mixing zone in the direction pointing in the opposite direction to the main flow direction.
- the channels running separately from each other are therefore preferably inclined at least slightly in the direction opposite to the main flow direction in the areas of their mouths into the mixing zone. Since the fluid flow then usually leaves the mixing zone in the distal direction, a highly turbulent flow can be produced in this way.
- the mixing structure has at least one transfer channel and a separation region into which the transfer channel opens, and from which extend the two channels extending separately from one another.
- the mixing of the substances in the mixing structure is then based on the fundamental principle that the fluid flow guided in the transfer channel is divided in the separation region into two separate fluid streams, which are then brought together again under turbulent flow in a mixing zone.
- the mixing structure may in particular be designed such that the mixing is repeated several times according to this principle.
- the mixing structure in this case comprises melirer pairs of separate channels and melirere mixing zones, in each of which a pair of two separate channels opens, wherein the transfer channel connects a mixing zone and a separation region with each other.
- the two separate channels which are together form a pair, arranged in the main flow direction at approximately the same height.
- a large part of the Miseh für is even formed mirror-symmetrical.
- a pair of two separate channels preferably forms the approximate shape of a heart, respectively.
- the mixing structure preferably has at least three, in particular at least five, and most preferably even more than eight pairs of channels running separately from one another, and preferably at least three, in particular at least five, and most preferably even more than eight mixing zones into each of which a pair of two separate channels opens.
- the mixing of the substances can thereby be further improved.
- the base element which may be, for example, the housing of a spray head
- the hollow needle of a cannula or a catheter tube a mixing chamber and a swirl chamber are preferably formed.
- a plurality of essentially identical mixing structures are formed on the insert part, which can be arranged in particular on diametrically opposite sides of the insert part.
- the mixing device may have a Luer connection, which serves to connect the mixing device to the discharge unit.
- Luer connections are well known to the person skilled in the art and usually have cones with a standardized pitch of 6%.
- a set comprising a discharge unit and a mixing device as indicated above.
- the mixing device can be connected to the discharge unit such that one or more substances can be discharged from the discharge unit through the mixing device and can be mixed in the mixing device.
- Fig. 1 is a perspective view of a connected to a discharge unit
- Fig. 2 is a perspective view of the mixing device of Figure 1, before the
- Fig. 3 is a central sectional view in the plane indicated in Figure 4
- Fig. 4 is a side view of the connected to a discharge unit
- Fig. 5 is a central sectional view in the plane indicated in Figure 4
- V-V of the mixing device of FIG. 1 connected to a discharge unit;
- FIG. 6 is an enlarged partial view of the area marked in FIG. 3;
- FIG. 7 is an enlarged partial view of the area marked in FIG. 5; FIG.
- FIG. 8 shows a sectional view in the plane VII1-V1II of the mixing device of FIG. 1, marked in FIG. 6;
- Fig. 9 is a sectional view in the plane indicated in Figure 6 IX-IX
- Fig. 10 is a sectional view in the marked in Figure 3 plane X-X of
- FIG. 1 is a side view of a mixing device according to a second, inventive embodiment, in the form of a cannula;
- FIG. 12 is a central sectional view through the mixing device of FIG. 11; FIG.
- Fig. 13 is an enlarged partial view of the area marked in Fig. 12;
- Fig. 14 is a side view of a compared to FIG 11 perpendicular Viewing direction of the mixing device of Figure 11, with dashed lines indicated inner life;
- FIG. 1 is a sectional view in the plane XVIII- marked in FIG.
- FIGS. 1 to 10 show a mixing device according to a first embodiment of the invention.
- the mixing device is formed in this embodiment as a spray head 3 and connected via a connecting part 5 to two individual syringes 2 connected together.
- the individual syringes 2 together with the connection part 5 a discharge unit 1.
- the connection part 5 By means of the connection part 5, the two distal outputs of the individual syringes 2 are brought together to form a single Luer connection 56, to which the spray head 3 can be connected.
- the spray head 3 is used in particular for mixing and atomizing the substances contained in the discharge unit 1.
- the discharge unit 1 as shown in Figures 1 to 5, two parallel arranged reservoirs 21 and 22, which serve for the storage of different substances, which are to be mixed together immediately before the application or the discharge.
- the individual syringes 2 each have a piston 4, which is arranged displaceably in the reservoir 21 or 22.
- the two pistons 4 can be connected to each other in particular in the region of their proximal pressure surfaces.
- a device can be used, as disclosed in WO 2010/009563.
- the reservoirs 21, 22 each have a male Luer cone 23, through which the substance stored in the reservoir 21 or 22 can be discharged by means of the pistons 4 in the distal direction.
- the male Luer cone 23 in each case surrounds the outlet opening of the corresponding reservoir.
- securing sleeves 24 are provided with internal threads, which are each attached to the male Luer cone 23 around at the distal ends of the reservoirs 21, 22.
- connection part 5 The configuration of the connection part 5, which is clearly visible in particular in FIG. 6, is described in detail in WO 2011/1 16484.
- the connection part 5 essentially has a housing 53 with two female Luer cones 54 pointing in parallel directions, which serve for connecting the connection part 5 to the two male Luer cones 23 of the syringes 2.
- a rotary element 5 1 is arranged around the female luer cones 54, which can be screwed into the securing sleeves 24 of the syringes 2 by means of a threaded sleeve 52.
- the connection part 5 can thereby be connected in a sealing manner to the male Luer cones 23 of the syringes 2 with both female Luer cones 54.
- connection part 5 thus has two separate outlet openings, which open outward on the distal side of the male Luer cone 56.
- a Locking sleeve 57 rotatably mounted, which serves to secure a connected to the male Luer cone 56 connecting element.
- the spray head 3 which is in particular a mixing device, consists in the present embodiment of two components, namely a housing 31 and an insertable into the housing 31 insert 32.
- a housing 31 In the figure 2 is the lei 1 32 in a slightly in shown in the proximal direction of the housing 31 pulled out position.
- the design of the housing 31 is clearly visible in particular in FIGS. 2 and 6 to 10. It has, in particular with regard to the configuration of the end wall 318, a similar embodiment, as disclosed in EP 2 018 132 mixing and Zerstäuber harmonye.
- the housing 31 has a substantially hollow-cylindrical shape, which is closed towards its distal end by means of a terminating wall 318.
- the housing 31 forms a female Luer cone 316 in the region of its opening pointing to the proximal side.
- This female Luer cone 316 serves to connect the spray head 3 to a discharge unit and, in the present exemplary embodiment, in particular to the male Luer cone 56 of the connection part 5
- an external thread 319 is provided on the outside of the female Luer cone 316.
- the housing 31 can be secured to the connection part 5 when it is connected to the female Luer cone 54.
- a circumferential side wall 3 17 extends in the distal direction.
- the distally tapered inner surface of the female Luer cone 316 is continued with its standardized pitch of 6% continuously within the side wall 317.
- an outlet opening 315 of the spray head 3 is formed, through which pass the two substances mixed together from the reservoirs 21, 22 of the syringe 2 to the outside.
- an outlet channel 326 of the insert 32 on the distal side of the insert 32 opens into an annular space 327, which is bounded by the insert 32, the side wall 317 and the end wall 318.
- introduction conduits 314 each open into the annular space 327 with their region arranged radially outwards.
- the introduction conduits 314 extend from the outside inwards essentially in the circumferential direction, and then merge tangentially into a concentric manner in the curve via a curve bent radially inward End wall 318 formed annular space, which forms a mixing chamber 311.
- Placed relative to the feed lines 314 extend from the radial inside of the mixing chamber 31 1 four feed channels 313, which are arranged circumferentially at regular intervals, tangent to a centrally formed in the closure wall 318, circular swirl chamber 312. In the central center of the swirl chamber 3 12, the outlet opening 3 1 5 is arranged.
- the introduction lines 314, the mixing chamber 31 1, the supply channels 313 and the swirl chamber 312 are all open towards the proximal side of the end wall 318 and are, with the exception of the introduction 314, which open into the annulus 327, when properly inserted into the housing 31 Insert 32 is closed from the distal end surface of the insert 32 completely to the proximal side.
- the insert 32 is, when it is used as intended in the housing 31, with its radial outer surface sealingly against the inner surface of the side wall 317 of the housing 31 at.
- the securing sleeve 57 By tightening the securing sleeve 57, the housing 31 is attracted in the proximal direction to the connector part 5, and the insert member 32 is accordingly pressed into the interior of the housing 31 due to the abutment on the distal end surface of the male Luer cone 56.
- the insert part 32 with its radial outer side is pressed more strongly against the side wall 317, the further it is pressed into the interior of the housing 31.
- the sealing effect between the housing 31 and insert 32 thereby increases.
- the insert 32 has an overall substantially cylindrical configuration. It may, but need not, have a slightly tapered conical configuration in the distal direction.
- the proximal end region of the insert part 32 has a conically tapering section in the distal direction.
- a circumferential shoulder is provided which serves to form the annular space 327.
- the insert part 32 has a mixing structure 320 with mixing channels 321, 324, 325 and 326, which extends in the distal direction over the entire length of the insert part 32.
- the mixing structure 320 is designed groove-shaped, which means that the mixing channels 321. 324, 325 and 326 are each open in the radial direction to the outside.
- the mixing structure 320 forms mixing channels 321, 324, 325 and 326 in the form of laterally closed, tubular fluid conduits which are laterally bounded by the insert 32 and the inner surface of the sidewall 317 of the housing 31 ,
- the Insert 32 formed two mutually parallel supply channels 321.
- These supply channels 321 open on the pointing in the proximal direction end face of the insert member 32 in each case one of the fluid lines 55 of the connecting part 5.
- the supply channels 321 are each bent by almost 180 ° to each other and in the proximal direction.
- the two supply channels 321 each open into a first mixing zone 322. The two substances from each of the Reservoirs 21 and 22 first come into contact with each other in this first mixing zone 322.
- a first transfer channel 325 extends in the distal direction.
- This first transfer channel 325 opens at its distal end into a separation region 323, from which two separate channels 324 extend laterally away from one another and slightly extend in the distal direction.
- the channels 324 are each bent by approximately 180 ° towards each other, so that at the end of this bend substantially parallel to the longitudinal direction of the insert part 32 in FIG the proximal direction.
- the two channels 324 are brought together in each case via a bend in a second mixing zone 322 such that the substances, projected onto the longitudinal direction of the insert part 32, respectively reach the mixing zone 322 in the proximal direction.
- the two fluid streams in turn meet in the second mixing zone 322 of two mutually almost directly opposite directions from the channels 324 to each other.
- the mixing zones 322 can thereby also be referred to as turbulent zones.
- a further transfer channel 325 extends in the distal direction up to a second application region 323, in which the fluid flow. again divided into two separate channels 324. These two channels 324 are initially away from each other and in the distal direction. Then they open.
- an exit channel 326 extends in an inclined direction relative to the longitudinal direction of the insert 32 in the distal direction.
- the outlet channel 326 opens into the annular space 327.
- the mouth of the outlet channel 326 may in particular lie directly opposite one of the mouths of the introduction lines 314 of the housing 31.
- the mixing structure 320 in the present exemplary embodiment when viewed from the insert 32, is designed to be mirror-symmetrical overall from the side.
- the pairs of separate channels 324 each form the shape of a heart. In the present embodiment, which is clearly visible in FIG. 7, two such heart-shaped patterns can be seen.
- FIGS. 1 to 22 show a second embodiment of the present invention. Functionally equivalent elements are in this embodiment in each case with the same reference numerals as in the first embodiment shown in Figures 1 to 10.
- the mixing device is not designed as a spray head 3, as in FIGS. 1 to 10, but as a cannula 6.
- the cannula 6 has a holder 61 and a hollow needle 62 held therein.
- the holder 61 has a substantially hollow cylindrical shape with a circumferential side wall 612.
- the hollow needle 62 protrudes with its proximal end portion into the interior of the holder 61 and is there fixedly connected to the side wall 612.
- an external thread 61 1 is formed, by means of which the cannula 6 can be connected to a discharge unit, in particular the discharge unit 1 with the connection part 5.
- the external thread 61 1 surrounds a female luerusus 613.
- Gripping structures 614 are also formed on the outside of the side wall 612 in order to facilitate handling of the cannula 6.
- the hollow needle 62 is overall formed substantially hollow cylindrical with a circumferential side wall 622. At its distal, tapered end, the hollow needle 62 has an outlet opening 621 on.
- an insert 32 is inserted into the interior of the hollow needle 62, which in particular rests in a sealing manner against the inner surface of the side wall 612.
- two mixing structures 320 are formed on diametrically opposite sides, which are configured substantially similar to the mixing structure 320 of the first embodiment shown in FIG.
- the two mixing structures 320 of the present embodiment each have only one feed channel 321.
- This feed channel 321 in each case opens directly into a first axis separation region 323.
- the mixing structures 320 of the present embodiment each have a much larger number of pairs of channels 324 extending apart from one another in comparison to the mixing structure 320 shown in FIG. which each form a heart-shaped pattern. In the present case, a total of 12 such pairs of channels 324 are present.
- the housing 31, the holder 61 and in particular the insert 32 are in the present embodiments each made in one piece from a plastic by means of an injection molding process.
- the mixing structure 320 can be milled into the outside of the insert 32 during manufacture. But it can also be produced by injection molding by means of an appropriately trained injection mold.
- the mixing structure does not necessarily have to be formed on the outside of the insert part.
- it could also be formed by mixing channels which extend completely inside the insert part.
- the insert 32 could also be integrally formed in an alternative embodiment, together with the housing 31 and the hollow needle 62.
- the discharge unit need not necessarily be designed as two individual syringes connected to one another, but it could also be, for example, a double or multiple syringe or a single syringe in which the two substances are admitted in the same reservoir, but not yet in one sufficiently mixed condition.
- the discharge unit need not necessarily be designed as two individual syringes connected to one another, but it could also be, for example, a double or multiple syringe or a single syringe in which the two substances are admitted in the same reservoir, but not yet in one sufficiently mixed condition.
- a variety of other modifications is conceivable.
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Accessories For Mixers (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201380044214.2A CN104582823B (zh) | 2012-08-21 | 2013-07-09 | 用于排料单元的混合设备 |
EP13737122.5A EP2888031A1 (de) | 2012-08-21 | 2013-07-09 | Mischvorrichtung für eine austrageinheit |
US14/419,995 US9375692B2 (en) | 2012-08-21 | 2013-07-09 | Mixing device for a discharge unit |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1432/12 | 2012-08-21 | ||
CH14322012 | 2012-08-21 |
Publications (1)
Publication Number | Publication Date |
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WO2014029035A1 true WO2014029035A1 (de) | 2014-02-27 |
Family
ID=48792916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CH2013/000121 WO2014029035A1 (de) | 2012-08-21 | 2013-07-09 | Mischvorrichtung für eine austrageinheit |
Country Status (4)
Country | Link |
---|---|
US (1) | US9375692B2 (zh) |
EP (1) | EP2888031A1 (zh) |
CN (1) | CN104582823B (zh) |
WO (1) | WO2014029035A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3219382A1 (en) * | 2016-03-15 | 2017-09-20 | OP-Hygiene IP GmbH | Valvular conduit |
GB2616678A (en) * | 2022-03-18 | 2023-09-20 | Gurit Uk Ltd | Mixing and dispensing of two-component curable resin systems |
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US20170225191A1 (en) * | 2014-08-19 | 2017-08-10 | Medmix Systems Ag | Rotary dispenser for multiple cartridge |
JP6189351B2 (ja) * | 2015-03-18 | 2017-08-30 | 株式会社東芝 | 流路構造 |
US10596069B2 (en) * | 2015-12-22 | 2020-03-24 | Ethicon, Inc. | Syringes with mixing chamber in a removable cap |
CA3072692A1 (en) * | 2017-09-18 | 2019-03-21 | Cmp Products Limited | Apparatus for dispensing curable material into a cable gland |
CN110215563A (zh) * | 2019-05-08 | 2019-09-10 | 浙江一缘医疗器械有限公司 | 一种全自动混合注射泵及系统和使用方法 |
US11484850B2 (en) * | 2019-09-26 | 2022-11-01 | Tasz, Inc. | Aerator |
EP4069331A1 (en) * | 2019-12-05 | 2022-10-12 | Amgen Inc. | Flow restrictor for drug delivery device |
WO2024076590A2 (en) * | 2022-10-03 | 2024-04-11 | West Pharmaceutical Services, Inc. | Methods and adapters for mixing pharmaceutical complexes |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3219382A1 (en) * | 2016-03-15 | 2017-09-20 | OP-Hygiene IP GmbH | Valvular conduit |
US10299636B2 (en) | 2016-03-15 | 2019-05-28 | Op-Hygiene Ip Gmbh | Valvular conduit |
USRE49597E1 (en) | 2016-03-15 | 2023-08-08 | Op-Hygiene Ip Gmbh | Valvular conduit |
GB2616678A (en) * | 2022-03-18 | 2023-09-20 | Gurit Uk Ltd | Mixing and dispensing of two-component curable resin systems |
Also Published As
Publication number | Publication date |
---|---|
US9375692B2 (en) | 2016-06-28 |
CN104582823A (zh) | 2015-04-29 |
CN104582823B (zh) | 2017-02-22 |
EP2888031A1 (de) | 2015-07-01 |
US20150190770A1 (en) | 2015-07-09 |
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