WO2013147350A1 - Composition cosmétique contenant un extrait de la plante apios americana et son procédé de préparation - Google Patents

Composition cosmétique contenant un extrait de la plante apios americana et son procédé de préparation Download PDF

Info

Publication number
WO2013147350A1
WO2013147350A1 PCT/KR2012/002421 KR2012002421W WO2013147350A1 WO 2013147350 A1 WO2013147350 A1 WO 2013147350A1 KR 2012002421 W KR2012002421 W KR 2012002421W WO 2013147350 A1 WO2013147350 A1 WO 2013147350A1
Authority
WO
WIPO (PCT)
Prior art keywords
apios
extract
cosmetic composition
weight
tubers
Prior art date
Application number
PCT/KR2012/002421
Other languages
English (en)
Korean (ko)
Inventor
조송미
김대곤
이진종
조성수
Original Assignee
전남과학대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 전남과학대학교 산학협력단 filed Critical 전남과학대학교 산학협력단
Priority to PCT/KR2012/002421 priority Critical patent/WO2013147350A1/fr
Publication of WO2013147350A1 publication Critical patent/WO2013147350A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Definitions

  • the present invention relates to a cosmetic composition and a method for preparing the same, and more particularly, to a cosmetic composition and a method for producing the same containing an apiose extract excellent in antioxidant and antimicrobial activity.
  • the skin is the largest organ in the body and is always in direct contact with the external environment and acts as a protective shield to protect the living body from various irritation or dry environments. It is an organ in which new cells are actively produced and destroyed compared to other organs. In addition, it plays a very important role in protecting the body from physical abrasions, preventing the loss of moisture inside the body, protecting it from the ultraviolet rays generated from the sun, and controlling the body temperature.
  • Representative external aging factors include ultraviolet rays, and the most prominent external aging phenomenon is wrinkle formation (Daniell HW, Ann. Intern. Med., 1971, 75 (6), 873; Grove GL et al., J. Am. Acad Dermatol., 1989, 21 (3), 631; Griffiths CE et al., Arch.Dermatol., 1992, 128, 347).
  • One of the photoaging mechanisms caused by ultraviolet light is via free radical pathways (Harman D, J. Gerontol., 1956, 11 (3), 298).
  • Free radicals are known to cause breakdown of connective tissue formation such as skin collagen, inhibition of cell membrane function, promotion of DNA mutation, modification of protein function, intercellular energy transfer, and modification of molecules related to metabolism (Lavker RM and Kligman AM, J. Invest.Drmatol., 1988, 90, 325).
  • the fact that free radicals are involved in aging means that antioxidants or various chemical scavengers that inactivate the free radicals can be used to delay the aging process.
  • Antioxidants such as tocopherol, polyphenols, Coenzyme Q 10, BHT, and BHA are widely used for the purpose of removing such free radicals, but most of them are synthetic products, and thus their use is limited due to safety issues when applied to human skin for a long time. As a result, many studies have been made in anticipation of the development of natural antioxidants of plant origin, which have high antioxidant effects, are guaranteed to be safe for human skin, and are economical.
  • Apios americana Medikus is a legume that is vine-like and forms mycorrhizal fungi and tubers in the basement.
  • Apios is a temperate and subtropical region of eastern North America, ranging from southeastern Canada to Florida and Texas, USA (Blackmon and Reynolds. 1986; Seabrook and Dionne. 1976). Wild tubers, which are formed in the form of beads in the basement, are used by North American Indians for edible and gangjeong, and are distributed near ancient Indian settlements.
  • Blackmon and Reynolds. 1986; Reynolds et al., 1990; Reynolds, 1995 there is a record that early white migrants collected and used it for food, and it was spread to Europe in the 17th century, and an attempt was made to produce crops.
  • tubers of apios are known to be used directly for food, such as grilling, frying and cooking.
  • Tubers are composed of starch and protein, and the protein content is known to be three times higher than threshing crops using tubers (Ameny et al., 1994; Walter, 1986; Wickremesinhe et al., 1988).
  • apios contains various components such as vitamin C while researching to find plant species having skin improvement effect, and the extract extracted from apios has excellent antioxidant and antibacterial activity.
  • the present invention was completed by confirming the fact.
  • the present invention provides a cosmetic composition and a method for preparing the same, which have an anti-aging, whitening, wrinkle improvement, atopic improvement and a safe use without irritation to the skin by using an apios extract having excellent antioxidant and antibacterial activity. Its purpose is to.
  • Cosmetic composition using apios of the present invention for achieving the above object is characterized in that it comprises an apios extract extracted from Apios ( Apios americana Medikus) as an active ingredient.
  • the apios extract is an extract extracted by adding at least one extractant selected from water, a lower alcohol having 1 to 4 carbon atoms, a polyhydric alcohol, or a mixture thereof to at least one selected from the flowers, leaves, and tubers of the apios. It is done.
  • the apios extract is characterized in that the extract extracted from the fermented product at least one selected from the flowers, leaves, tubers of the apios.
  • a method for producing a cosmetic composition using the apios of the present invention for achieving the above object comprises the steps of: a) extracting the apios extract from Apios ( Apios americana Medikus); b) Add the apios extract to 0.01 to 20% by weight based on the total weight of the composition, lotion, lotion, cream, essence, pack, makeup base, foundation, body oil, body lotion, cleansing oil, cleansing foam It is characterized in that it comprises a; preparing into any one of the formulation selected from hair oil, hair shampoo and hair rinse.
  • the step a) is characterized in that the apios extract is extracted from the fermented product by mixing the fermentation strain with sugar to at least one selected from the flowers, leaves, tubers of the apios.
  • the present invention provides a cosmetic composition that can be used safely without irritation to the skin by containing an active ingredient extracted from apiose which is a natural plant.
  • the cosmetic composition of the present invention comprises an apios extract extracted from Apios ( Apios americana Medikus) as an active ingredient.
  • apios is rich in vitamins A, C, and various minerals and is excellent in antioxidant and moisturizing activity, and is expected to have skin improvement effects such as anti-aging, whitening, wrinkle improvement, anti-inflammatory, and moisturizing.
  • the apios extract refers to an extract obtained from various organs or parts of the apios as well as the tubers of the apios, and preferably means an extract extracted from at least one selected from flowers, leaves, and tubers.
  • Apios extract can be extracted in a variety of ways, preferably by mixing 2 to 20 times the weight of the extraction solvent with respect to apios, and then hot water extraction, cold needle or hot needle extraction for 1 to 20 hours at 10 to 150 °C Can be used. In addition, in the case of cold or hot extraction can be extracted longer than the time. For example, extraction solvent is added for 10 to 20 days. In addition, reflux cooling extraction, ultrasonic extraction method and the like can be used. In addition to the above-described extraction method, it includes an extract that has undergone a conventional purification process. For example, the active fraction obtained through various purification methods additionally performed, such as separation using an ultrafiltration membrane having a constant molecular weight cut-off value and separation by various chromatography, is also included in the extract.
  • At least one selected from water, a lower alcohol having 1 to 4 carbon atoms, a polyhydric alcohol, or a mixture thereof may be used as the extraction solvent.
  • Methanol, ethanol, etc. can be used as a C1-C4 lower alcohol
  • Butylene glycol, propylene glycol, pentylene glycol, glycerol, etc. can be used as a polyhydric alcohol.
  • the mixture may be a mixture of water and lower alcohol, a mixture of water and polyhydric alcohol, a mixture of lower alcohol and polyhydric alcohol, or a mixture of water and lower alcohol and polyhydric alcohol.
  • the extract may be obtained in powder form through freeze drying, spray drying, etc.
  • apiose extract is extracted from the fermented fermented apios. Specifically, the fermented product obtained by mixing fermentation with sugar and fermented strain in apios is extracted by centrifugation.
  • apiose finely chop one or two selected from flowers, leaves, tubers of apios, and then mix them with sugar and put them in a fermentation vessel. At this time, the mixing ratio of 20 to 40 parts by weight per 100 parts by weight of apiose is added to the fermentation vessel.
  • sugar oligosaccharides, lactose, glucose, fructose, sugar, etc. may be used alone or in combination.
  • the fermentation vessel is preferably used onggi. Fermented bacteria are inoculated into the mixture of apios and sugar and stored at 20 to 30 ° C. for 2 to 4 months to ferment.
  • Fermentation temperature and fermentation period are closely related. If fermentation is carried out at high temperature exceeding 30 °C, it becomes a good environment for microorganisms to grow regardless of the type, and there is a possibility of deterioration or decay by harmful microorganisms. In addition, since the fermentation broth is not sufficiently fermented at a temperature of less than 20 ° C., a desired fermentation broth cannot be obtained and the fermentation period is long.
  • Fermentation bacteria are inoculated with 0.01 to 0.03 parts by weight based on 100 parts by weight of the mixture of apiose and sugar.
  • fermentation bacteria yeast, yeast or lactic acid bacteria can be used.
  • Saccharomyces cerevisiae is used as a yeast.
  • the fermented product mixed with liquid and solid is added to a grinder and finely ground and homogenized. Homogenized fermentation is centrifuged to obtain an apios extract.
  • the cosmetic composition of the present invention preferably contains 0.01 to 20% by weight of the apios extract based on the total weight of the composition. If the apiose extract is less than 0.01% by weight, the antioxidant effect is insignificant, and if it exceeds 20% by weight it is difficult to have an elevated effect compared to the content.
  • Cosmetic composition of the present invention by adding a variety of well-known ingredients and the like using methods known in the art, lotion, lotion, cream, essence, pack, makeup base, foundation, body oil, body lotion, cleansing oil, cleansing foam It may be prepared in any one of the formulations selected from hair oil, hair shampoo and hair rinse.
  • the formulation of the cosmetic composition of the present invention is a paste, cream or gel, pack, as known components, animal fibers, plant fibers, waxes, paraffins, starches, tragacanth, cellulose derivatives, polyethylene glycol, silicone, bentonite, Silica, talc or zinc oxide and the like can be used.
  • the formulation of the cosmetic composition of the present invention is a powder
  • lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used.
  • a solvent, solvating agent or emulsifying agent such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1, 3-butylglycol oil, glycerol aliphatic ester, polyethyleneglycol or sorbitan non-dispersion ester and the like can be used.
  • liquid diluents such as ethanol or propylene glycol
  • suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol esters and polyoxyethylene sorbitan esters, microcrystalline Cellulose, aluminum metahydroxy, bentonite, agar or tragacanth and the like can be used.
  • cosmetic composition of the present invention can be used as a conventional known ingredients such as stabilizers, solubilizers, vitamins, pigments and fragrances, can be prepared in any formulation commonly prepared in the art, Can be appropriately selected accordingly.
  • the lotion may be 1.5% by weight of ethanol, 1.0% by weight of natural liquid, 3.0% by weight of betaine, 3.0% by weight of diethan panthenol, 1.0% by weight of sebum-A, 2.0% by weight of arbutin paste, 2.0% by weight of anenosine, eco gum It may be composed of 0.03% by weight, glycerin 4.0% by weight, collagen 1.0% by weight, apiose extract 5.0% by weight, preservatives (trace), purified water (residual amount).
  • the lotion may include 1.0 wt% of carbomer, 2.0 wt% of dimethicone, 5.0 wt% of jojoba oil, 0.5 wt% of provitamin E, 1.0 wt% of olive emulsion wax, 5.0 wt% of arbutin paste, and T-mixture.
  • an example of the formulation of the cream is 1.5% by weight of cetearyl alcohol, 1.0% by weight of glyceryl stearate, 1.0% by weight of polysorbate 60, 0.3% by weight of sorbitassesquioleate, 6.0% by weight of cetyloctanoate, Squalane 8.0 wt%, Apricot kernel oil 4.0 wt%, Dimethicone 2.0 wt%, Butylene glycol 4.0 wt%, Glycerin 4.0 wt%, Magnesium aluminum silicate 0.4 wt%, Apiose extract 5.0 wt%, Blending essence oil (Trace amount), preservative (trace amount), and purified water (residual amount).
  • the essence is 1.5% by weight of ethanol, 1.0% by weight of natural liquid, 1.0% by weight of carbomer, 3.0% by weight of betaine, 2.0% by weight of adenosine, 5.0% by weight of arbutin paste, aqueous sodium hyaluronate solution (1%) It may be composed of 0.03% by weight, Diel panthenol 3.0% by weight, glycerin 4.0% by weight, Sebum-A 1.0% by weight, apiose extract 5.0% by weight, blending essence oil (trace), preservative (trace), purified water (residual amount). .
  • the foundation may be 2.0% by weight of stearic acid, 0.5% by weight of cetearyl alcohol, 1.0% by weight of glyceryl stearate, 0.5% by weight of polysorbate 60, 0.7% by weight of sorbitan sesquioleate, hydro 2.0% by weight of genelade seed oil, 5.0% by weight of sunflower oil, 6.0% by weight of squalane, 4.0% by weight of cetyloctanoate, 2.0% by weight of cyclomethicone, 5.0% by weight of butylene glycol, 3.0% by weight of glycerin Silicate 0.6%, xanthan gum 0.05%, titanium dioxide 10.0%, talc 3.0%, hydrated ferric oxide 1.3%, ferric oxide 0.3%, ferrus-ferric oxide 0.15%, preservative (trace) , Purified water (remaining amount), may be composed of 5% by weight of apios extract.
  • the pack is 0.5 wt% propylene glycol, 1.0 wt% natural liquid, 3.0 wt% polyvinyl alcohol, 3.0 wt% ethanol, 1.0 wt% carbomer, 2.0 wt% collagen, 1.0 wt% eco gum, peptide RF 1.0 wt%, Dipanthenol 3.0 wt%, Glycerin 4.0 wt%, Sebum-A 1.0 wt%, Adenosine 2.0 wt%, Apios extract 5.0 wt%, Blending essence oil (trace), Preservative (trace), Purified water (Remaining amount) It can be composed of).
  • the hair shampoo is 0.5 wt% polyquaternium, 1.0 wt% natural liquid, 3.0 wt% cocamidopropyl betaine, 3.0 wt% betaine, 7.0 wt% CDA, LES 25.0 wt%, cocobetaine 5.0 wt%, Collagen 1.0 wt%, Diel Panthenol 3.0 wt%, Glycerin 4.0 wt%, Sebum-A 1.0 wt%, Adenosine 2.0 wt%, Apiose extract 5.0 wt%, Blending essence oil (trace), Preservative (trace) , Purified water (residual amount).
  • the tubers of the apios collected in November were washed thoroughly and then dried naturally to prepare the apios tubers.
  • the prepared apios tuber was finely chopped, water was added 10 times by weight, heated at 100 ° C. for 6 hours, and the solids were filtered to prepare an apios extract.
  • apios extract The flowers of apios collected in August were washed thoroughly and then dried naturally to prepare apios flowers. Water was added 10 times by weight to the prepared apios flower, heated at 100 ° C. for 6 hours, and the solids were filtered to prepare an apios extract.
  • Apiose extract was prepared by adding 90% ethanol 5 times by weight to the apios flower prepared in Example 3 and cooling for 6 hours at room temperature.
  • a skin test was conducted to determine the degree of skin irritation for the first to fifth test samples.
  • a special patch (IQ chamber, Chemotechnique, Sweden) containing a sample was applied to the back of 20 men and women (mean age 26.5 ⁇ 1.5 years) and removed 24 hours later and read after 30 minutes. 24h single epicutaneous patch test was performed.
  • the degree of response of the skin was determined as 1-4 points according to the ICDRG (International contact dermatitis research group) evaluation criteria for erythema, edema, crust and shallow ulcer, and recorded as a total average value.
  • ICDRG International contact dermatitis research group
  • the antimicrobial effect on the first to fifth test samples was tested.
  • the size of the growth zone (clear zone) for each test sample was observed in Table 3 below.
  • sorbic acid used as a preservative was used as a control.
  • the cosmetic composition of the present invention is expected to have an effective antibacterial activity to reduce inflammation of the skin and to remove the itch due to the anti-inflammatory effect on sensitive skin or atopic dermatitis.
  • the antioxidant donation ability (EDA%) of the samples was measured by modifying Blois' method. 0.5 mL of 0.2 mM DPPH (1,1-diphenyl-2-picryl hydrazyl) was added to 2 mL of the sample solution, stirred for 30 minutes, and the absorbance was measured at 517 nm. The electron donating effect was expressed by the absorbance reduction rate of the sample solution addition and no addition solution. Radical scavenging activity was calculated by the following equation.
  • Radical scavenging activity (%) (absorbance of 1-sample addition / absorption of no addition) ⁇ 100
  • the radical scavenging activity of the first to fifth test samples was higher than the scavenging ability of the BHT (synthetic antioxidant) used as a control 50.2 ⁇ 0.45. And the 5th test sample extracted from the fermentation product had the highest radical scavenging activity.
  • the present invention is effective in preventing skin aging, whitening, and improving wrinkles by enhancing the physiological activity of the skin by the antioxidant effect of protecting the skin from active oxygen with excellent antibacterial effect.

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

Cette invention concerne une composition cosmétique et son procédé de préparation, et plus précisément, une composition cosmétique qui contient un extrait de la plante Apios americana présentant des propriétés antioxydantes et antibactériennes excellentes, et qui améliore la peau, et son procédé de préparation. La composition cosmétique de l'invention contient un extrait de la plante Apios americana, cet extrait étant obtenu par extraction des fleurs, des feuilles et/ou des tubercules de la plante avec au moins un solvant d'extraction choisi parmi l'eau, un alcool inférieur en C1-C4, un polyol et leur mélange.
PCT/KR2012/002421 2012-03-30 2012-03-30 Composition cosmétique contenant un extrait de la plante apios americana et son procédé de préparation WO2013147350A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/KR2012/002421 WO2013147350A1 (fr) 2012-03-30 2012-03-30 Composition cosmétique contenant un extrait de la plante apios americana et son procédé de préparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2012/002421 WO2013147350A1 (fr) 2012-03-30 2012-03-30 Composition cosmétique contenant un extrait de la plante apios americana et son procédé de préparation

Publications (1)

Publication Number Publication Date
WO2013147350A1 true WO2013147350A1 (fr) 2013-10-03

Family

ID=49260575

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/002421 WO2013147350A1 (fr) 2012-03-30 2012-03-30 Composition cosmétique contenant un extrait de la plante apios americana et son procédé de préparation

Country Status (1)

Country Link
WO (1) WO2013147350A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106726715A (zh) * 2017-03-14 2017-05-31 上海蔻沣生物科技有限公司 一种具有提拉米苏外观状态的粉底霜及其制备方法
CN110573029A (zh) * 2017-05-15 2019-12-13 姜承赞 使用乳酸菌的天然产物酶及其制造方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030089710A (ko) * 2001-04-06 2003-11-22 가부시키가이샤 도요학코 미용화장품 소재 및 그 제조방법
KR20050080085A (ko) * 2005-07-11 2005-08-11 조정일 발효콩 추출물을 이용한 건강 증진 목욕제 및 피부미용제
JP2007332092A (ja) * 2006-06-16 2007-12-27 Sansho Seiyaku Co Ltd 皮膚外用剤
JP2008194032A (ja) * 2007-01-17 2008-08-28 Kazue Takoji 発酵食品と発酵食品の製造方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030089710A (ko) * 2001-04-06 2003-11-22 가부시키가이샤 도요학코 미용화장품 소재 및 그 제조방법
KR20050080085A (ko) * 2005-07-11 2005-08-11 조정일 발효콩 추출물을 이용한 건강 증진 목욕제 및 피부미용제
JP2007332092A (ja) * 2006-06-16 2007-12-27 Sansho Seiyaku Co Ltd 皮膚外用剤
JP2008194032A (ja) * 2007-01-17 2008-08-28 Kazue Takoji 発酵食品と発酵食品の製造方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106726715A (zh) * 2017-03-14 2017-05-31 上海蔻沣生物科技有限公司 一种具有提拉米苏外观状态的粉底霜及其制备方法
CN110573029A (zh) * 2017-05-15 2019-12-13 姜承赞 使用乳酸菌的天然产物酶及其制造方法

Similar Documents

Publication Publication Date Title
KR101393007B1 (ko) 람부탄 및 리치 추출물을 유효성분으로 함유하는 피부노화방지용 및 피부주름 개선용 화장료 조성물
KR101458887B1 (ko) 히카마, 콜리플라워, 말로우 및 아이슬란드 이끼 천연 복합추출물을 유효성분으로 함유하는 항산화, 보습, 피부 자극 완화 효과를 갖는 피부 개선용 화장료 조성물
KR101184427B1 (ko) 곰보배추를 이용한 피부 개선용 화장료 조성물 및 이의 제조방법
KR101555354B1 (ko) 발효식물을 이용한 화장료 조성물과 이의 제조방법 그리고 이를 이용한 헤어샴푸
WO2022177215A1 (fr) Procédé pour favoriser l'activité antioxydante de feuilles de thé pourpre
KR100984163B1 (ko) 차요테 추출물을 함유하는 보습용 화장료 조성물 및 이의 제조방법
CN109528590B (zh) 一种保湿防护乳及其制备方法
KR101227171B1 (ko) 아피오스를 이용한 화장료 조성물 및 이의 제조방법
KR20170052811A (ko) 녹차추출물의 효모발효액 및 이의 제조방법 그리고 이를 이용한 화장료 조성물
KR20100074688A (ko) 조직배양한 에키네시아 부정근 추출물을 포함하는 화장료 조성물 및 이의 제조 방법
KR102443283B1 (ko) 마이크로바이옴을 이용한 피부 장벽 개선 효과가 우수한 화장료 조성물
KR101469886B1 (ko) 화장료 조성물의 제조방법
KR100985228B1 (ko) 동아를 이용한 피부 개선용 화장료 조성물
WO2013147350A1 (fr) Composition cosmétique contenant un extrait de la plante apios americana et son procédé de préparation
KR20090081631A (ko) 미선나무 추출물을 유효성분으로 함유하는 화장료 조성물
CN113384510B (zh) 一种具有抗光老化、舒缓清凉功效的发酵组合物及其制备方法和应用
WO2019009663A1 (fr) Composition destinée à prévenir et à atténuer le pied d'athlète
KR20010000390A (ko) 김치추출물을 함유하는 노화 및 여드름을 포함한피부개선제 혼합조성물
KR100530669B1 (ko) 락테이트 및 감초 추출물을 포함하는 피부 미백용 화장료조성물
KR100466379B1 (ko) 피부미백용 조성물
KR100829718B1 (ko) 먼나무 추출물을 유효성분으로 포함하는 피부 미백용화장료 조성물
KR102282645B1 (ko) 천궁 및 황금 혼합 추출물 또는 이들의 분리화합물을 함유하는 여드름 및 비듬완화용 화장료 조성물
KR20110122448A (ko) 지리터리풀 추출물을 유효성분으로 함유하는 화장료 조성물
KR20150081201A (ko) 미백 화장료 조성물과 이의 제조방법
KR20190048931A (ko) 단삼 흑효모 발효액을 함유하는 화장료 조성물

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12872948

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 12872948

Country of ref document: EP

Kind code of ref document: A1