WO2013013498A1 - Boisson de médecine chinoise permettant de nourrir le cœur afin de calmer l'esprit - Google Patents

Boisson de médecine chinoise permettant de nourrir le cœur afin de calmer l'esprit Download PDF

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Publication number
WO2013013498A1
WO2013013498A1 PCT/CN2012/000984 CN2012000984W WO2013013498A1 WO 2013013498 A1 WO2013013498 A1 WO 2013013498A1 CN 2012000984 W CN2012000984 W CN 2012000984W WO 2013013498 A1 WO2013013498 A1 WO 2013013498A1
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WIPO (PCT)
Prior art keywords
rose
jujube
wheat
sweetener
food
Prior art date
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PCT/CN2012/000984
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English (en)
Chinese (zh)
Inventor
钟虹光
卢建中
吕毅斌
廖群
李诒光
唐兵
Original Assignee
江西食方食坊中药食品有限公司
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Publication of WO2013013498A1 publication Critical patent/WO2013013498A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/56—Flavouring or bittering agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Definitions

  • a traditional Chinese medicine drink that nourishes the heart and calms the nerves
  • the invention relates to a Yangxin Anshen Maizao Rose Drink and a preparation method thereof.
  • the invention is prepared by combining Huai wheat, jujube, licorice and rose flower with the famous Fangmai Ganzao jujube soup ( ⁇ , wheat, jujube).
  • Huai wheat which is mainly produced in the Jianghuai region, is called Huai wheat, and is good at raising the heart and mind. It is often used in conjunction with licorice and jujube for mental disorders such as dysfunction and restlessness. If the medicine is used together, it has the effect of nourishing the heart and calming the nerves.
  • Jujube has the functions of nourishing qi, nourishing blood, soothing the nerves, strengthening the spleen and stomach. It is a good health and nutrition for patients with weak spleen and stomach, lack of blood, fatigue, insomnia and dreams. Modern research shows that the cyclic adenosine monophosphate contained in jujube is an essential component of energy metabolism in human cells, which can enhance muscle strength, eliminate fatigue, dilate blood vessels, increase myocardial contractility, improve myocardial nutrition, and have good effects in preventing and treating cardiovascular diseases. effect.
  • Licorice has the functions of replenishing spleen and replenishing qi, nourishing cough and moistening the lungs. Clinically, it can be used for heart qi deficiency, heart palpitations, pulse generation, as well as spleen and stomach qi deficiency, fatigue and fatigue. Modern studies have shown that intraperitoneal injection of licorice extract inhibits chloroform-induced ventricular fibrillation, adrenaline-induced arrhythmias in rabbits, and aconitine-induced arrhythmias in rats, and can slow heart rate. Total flavonoids from licorice can prolong the latency of arrhythmia induced by aconitine and reduce the incidence of ventricular fibrillation induced by chloroform.
  • Rose qi stagnation, and blood, pain relief. For liver and stomach pain, eating less vomiting, irregular menstruation, falling and hurting. Modern studies have shown that rose oil promotes bile secretion in rats; rose has a protective effect on myocardial ischemia in experimental animals.
  • the invention adds roses on the basis of Ganmai jujube soup, and the rose flower enters the liver, which can relieve liver and qi, and plays a role of coordination, promotion and balance on licorice, jujube and wheat.
  • the invention has good mouthfeel, has the functions of nourishing the heart, calming the spleen and neutralizing the spleen and the middle spleen, and can improve palpitation, palpitations and menopausal depression and anxiety symptoms, and is suitable for the use of stagnation syndrome and menopausal population.
  • the object of the present invention is to provide a Yangxin Anshen Maizao Rose Drink and a preparation method thereof.
  • the drink has a good taste and has the functions of nourishing the heart, improving the spleen and neutralizing it. It can improve palpitation, palpitations and menopausal depression and anxiety symptoms. It is suitable for people with stagnation and menopause.
  • the present invention has been achieved by the following technical solutions.
  • a nourishing heart and tranquillity jujube rose beverage which is characterized by being prepared from the following raw material ingredients and weight ratio
  • the preferred weight ratio range of the present invention is: Huai wheat 3 ⁇ 40g, jujube 3 ⁇ 30g, licorice 2 ⁇ 15g, rose 2 ⁇ 10g, sweetener 0. 05 ⁇ 50g, vitamin C 0. 06 ⁇ 2g, wheat ⁇ 0. 03 ⁇ 1.
  • the best weight ratio of the present invention is: Huai wheat 15g, jujube 8g, licorice 3g, rose 3g, sweetener 40g, vitamin CO. 5g, wheat flavor 0. 12g.
  • the succulent rose drink as described above which is characterized in that it can also be added to the raw material ratio.
  • the jujube rose beverage as described above characterized in that the sweetener is fructose syrup, maltitol, mannitol, sorbitol, sucralose, cyclamate, aspartame, acesulfame, glycyrrhizin Any one or more of stevioside, egg white sugar, and scutellaria.
  • the sweetener is fructose syrup, maltitol, mannitol, sorbitol, sucralose, cyclamate, aspartame, acesulfame, glycyrrhizin Any one or more of stevioside, egg white sugar, and scutellaria.
  • the liquid is filtered, continue to add 6 ⁇ 10 times water decoction 0. 5 ⁇ 1. 5 hours, filtered, combined with the second filtrate, concentrated to 180 ⁇ 220ml, add sweetener, vitamin C and wheat flavor Add purified water to 300ml, mix well, filter, fill, sterilize, and get the finished product.
  • the preparation method of the jujube rose beverage as described above is characterized in that the finished product can also be various foods prepared by a conventional food preparation process using a food acceptable excipient or a food additive.
  • the jujube rose beverage as described above is characterized by the use in the preparation of a food or health supplement for nourishing ampoules.
  • the jujube rose drink of the present invention has anti-myocardial ischemia and sedative and hypnotic effects.
  • the specific experiments are as follows:
  • Maizao Rose Drink is provided by Jiangxi Shifang Food Square Traditional Chinese Medicine Food Co., Ltd. Kunming mice, weighing 18 ⁇ 22g, male and female, SPF, provided by Experimental Animal Center of Nanchang University, animal certificate number: 2010A063.
  • Adrenaline Hydrochloride Injection Provided by Guangzhou Mingxing Pharmaceutical Co., Ltd., batch number: 20100924; Blood glucose determination kit: Provided by Baoding Great Wall Clinical Reagent Co., Ltd., batch number: 20100225; Double-beam UV-visible spectrophotometer: Beijing Pu analysis General Instrument Co., Ltd. Provided by the responsible company, model: TU-1901;
  • mice half male and half female, were randomly divided into blank control group, model group, low-, medium-, and high-dose group of rose juice (10g crude drug/kg, 20g crude drug/kg, 40g crude drug/kg) according to body weight. 10 only.
  • Each drug-administered group was intragastrically administered with the corresponding drug.
  • the blank control group and the model group were given the same volume of normal saline for 20 days. After 30 minutes of non-administration, the mice were placed in a small animal tester to adapt to 3 After min, record the number of activities within 5 minutes.
  • the experimental data were expressed as "mean soil standard deviation", and statistical processing was performed using SPSS statistical software.
  • the raw materials were weighed according to the following ratios: Huai wheat 16 g, jujube 8 g, licorice 4 g, rose 3 g, maltitol 40 g, vitamin C0. 5 g, wheat flavor 0. 2 g.
  • Preparation method Weigh the medicine according to the prescription amount, add 12 times water soak for 0.5 hours, decoction for 1.5 hours, filter the liquid, continue to add 6 times water for 1 hour, filter, combine the second filtrate, concentrate to 200ml, add maltitol, vitamin C and wheat flavor, add purified water to 300ml, mix well, filter, fill, sterilize, that is, the finished product.
  • the finished dosage form may also be any dosage form prepared by using a pharmaceutically acceptable carrier or excipient, such as granules, tablets, capsules, soft capsules, pills, pills. .
  • the preparation method as described above is characterized in that the finished product may also be various forms of foods prepared by a conventional food preparation process using a food-acceptable excipient or a food additive.
  • the raw materials are weighed according to the following ratio: Huai wheat 46g, jujube 38g, licorice 17g, rose 13g, Tianqihua 5g, sorbitol 50g, sucralose 0. 03g, vitamin C0. 5g, wheat flavor 0. 17g.
  • the raw materials were weighed according to the following ratios: Huai wheat 3 g, jujube 2 g, licorice lg, rose 0.5 g, Tianqihua 0.5 g, sucralose 0.05 g, vitamin C 0.37 g, and wheat aroma 0.11 g.
  • the raw materials were weighed according to the following ratios: Huai wheat 15 g, jujube 6 g, licorice 3 g, rose 3 g, mannitol 45 g, vitamin C 0.42 g, and wheat flavor 0.14 g.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Neurosurgery (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

La présente invention a trait à une boisson de médecine chinoise permettant de nourrir le cœur afin de calmer l'esprit, laquelle boisson est constituée de Tritucum aestivurn L., de datte, de racine de réglisse et de fleur de rose de médicine chinoise. Le procédé de préparation de cette boisson comprend les étapes consistant : à peser le Tritucum aestivurn L., la datte, la racine de réglisse et la fleur de rose de médecine chinoise en fonction des poids, à ajouter 8 à 15 fois la quantité d'eau de manière à immerger le matériau pendant une durée allant d'une demi-heure à 1 heure 30, à procéder à une décoction pendant 1 à 2 heures, à filtrer le liquide médical, à ajouter en continu 6 à 10 fois la quantité d'eau de manière à procéder à une décoction pendant une durée allant d'une demi-heure à 1 heure 30, à filtrer, à combiner le filtrat, à ajouter un édulcorant, de la vitamine C et une fragrance de blé après condensation, à ajouter de l'eau à hauteur de 300 ml et à mélanger, filtrer, remplir, stériliser de manière à obtenir le produit.
PCT/CN2012/000984 2011-07-23 2012-07-23 Boisson de médecine chinoise permettant de nourrir le cœur afin de calmer l'esprit WO2013013498A1 (fr)

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CN201110207033XA CN102885346A (zh) 2011-07-23 2011-07-23 一种养心安神麦枣玫瑰饮料及其制备方法
CN201110207033.X 2011-07-23

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CN110353069A (zh) * 2019-08-29 2019-10-22 广州秋草堂健康科技有限公司 甘麦大枣汤及其制备方法
CN110742226A (zh) * 2019-10-18 2020-02-04 上海鹊喜生物科技有限公司 抗抑郁的固体饮料及其制备方法
CN111567652A (zh) * 2020-05-19 2020-08-25 深圳市凤火养生科技有限公司 一种用于调理气郁体质的养生茶及其制备方法

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