WO2012128305A1 - 顕微鏡 - Google Patents
顕微鏡 Download PDFInfo
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- WO2012128305A1 WO2012128305A1 PCT/JP2012/057277 JP2012057277W WO2012128305A1 WO 2012128305 A1 WO2012128305 A1 WO 2012128305A1 JP 2012057277 W JP2012057277 W JP 2012057277W WO 2012128305 A1 WO2012128305 A1 WO 2012128305A1
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- finger
- sample stage
- image
- touch screen
- display
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
- G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
- G06F3/03—Arrangements for converting the position or the displacement of a member into a coded form
- G06F3/041—Digitisers, e.g. for touch screens or touch pads, characterised by the transducing means
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N7/00—Television systems
- H04N7/18—Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
Definitions
- the present invention relates to a microscope including a touch screen disposed on a display surface of a display means.
- a typical example of a microscope such as a Raman microscope includes a sample stage mounted so as to be movable in the X and Y directions, X and Y direction driving means for driving the sample stage in the X and Y directions, and a plurality of objective lenses having different magnifications.
- a Z direction driving means for moving the sample stage and the revolver relative to each other in the Z direction, and any one of the plurality of objective lenses is selectively positioned at the working position facing the sample stage.
- Revolver driving means imaging means such as a CCD camera, image projecting optical means for projecting the image of the sample positioned on the sample stage to the imaging means through the objective lens positioned at the working position, and display means such as a liquid crystal panel And control means.
- control operations such as observation of the sample on the sample stage or selection of the measurement region, selection of observation or measurement magnification, and focusing of the objective lens.
- control operations are performed through input means such as a joystick or a track ball.
- input means such as a joystick or a track ball.
- the control operation using such input means is not always easy due to a time lag or the like existing between the input operation and the output operation such as movement of the sample stage, and requires considerable skill.
- observation or measurement is performed at a high magnification, the observation or measurement region is set roughly on the low magnification screen, and then the observation or measurement region is set sufficiently accurately at a high magnification. In this case, it is necessary to exchange the objective lens for focusing, and the operation is considerably complicated.
- Patent Documents 1 and 2 below disclose a microscope in which a touch screen is provided on a display surface of a display unit such as a liquid crystal panel and the touch screen is used as an input unit.
- the operation control mode in the microscope disclosed in the following Patent Documents 1 and 2 is based on finger contact or simple finger movement with respect to various function switches defined on the touch screen, and the control operation is limited.
- On the display means an image of the sample on the sample stage projected onto the imaging means via the image projection optical system is displayed, but there is a considerable amount of time between the input operation and the completion of movement of the sample stage. When there is a time lag and the sample stage is moved over a considerable length, it is necessary to repeat the area designation and waiting for the completion of the movement of the sample stage. It is necessary to correct the error at the center of the field of view, but the setting of the measurement area required in the case of a Raman microscope that does not consider such error correction is considered That is not, problems such as exists.
- the present invention has been made in view of the above-mentioned facts, and the main technical problem thereof is to sufficiently perform various operation controls of the microscope by using a touch screen disposed on the display surface of the display means as an input means. To provide a new and improved microscope that can be easily and precisely performed.
- the present inventors have made various gestures of the operator's finger applied to the touch screen disposed on the display surface of the display means, for example, contact (tap) with one finger. Touch two times in succession (double tap), move the finger without touching it (drag), touch the finger and keep it for a predetermined time (touch and hold), and touch the two fingers simultaneously Widening the distance between fingers by touching them (pinch out) or narrowing them (pinch in), and making two fingers touch each other at the same time to move them in parallel (double dragging). It has been found that the main technical problem can be achieved.
- a sample stage mounted so as to be movable in the X and Y directions, and an X and Y direction driving means for driving the sample stage in the X and Y directions
- a revolver including a plurality of objective lenses having different magnifications, a Z-direction driving means for relatively moving the sample stage and the revolver in the Z direction, and any one of the plurality of objective lenses
- Revolver driving means for selectively positioning at the working position opposite to the sample stage, imaging means, and projecting the image of the sample positioned on the sample stage to the imaging means through the objective lens positioned at the working position
- the control means is configured to actuate the X and Y direction driving means, actuate the Z direction driving means, actuate the revolver driving means, and display according to a gesture of an operator's finger applied to the
- the control device stores the image signal from the imaging unit in a built-in memory, and converts the image signal stored on the display surface of the display unit to the image signal.
- the memory image is displayed, and when the finger is moved without being detached from the touch screen, the memory image is moved on the display surface of the display means according to the movement of the finger, and the X and Y directions are displayed.
- the driving means is operated to move the sample stage in the X and / or Y direction.
- the control means detects the movement of the finger at a predetermined time interval from when the finger touches the touch screen until the finger is released from the touch screen, and updates the memory image based on the position of the finger.
- the image displayed on the display surface of the display unit is changed to a real-time image projected on the imaging unit. It is preferable to let it lie.
- the control means When two fingers are brought into contact with the touch screen at the same time, the control means stores the distance between the two fingers, so that the two fingers are not detached from the touch screen.
- the control unit preferably changes the magnification of the image displayed on the display surface of the display unit in accordance with the change rate of the interval between the two fingers.
- the control means activates the revolver driving means to change the objective lens located at the working position facing the sample stage.
- the control means stores the image signal from the imaging means in the built-in memory, and on the display surface of the display means during the operation of the revolver driving means.
- the control means based on the information on the same focal length and the visual field center position stored in advance in the built-in memory, the X direction and Y direction driving means and / or the Z direction.
- the driving means is operated to adjust the focus, and then the screen displayed on the display surface of the display means is changed to a real-time image projected on the imaging means.
- the control unit is configured to display the display unit on the display surface.
- a wide-field buffer image to which an additional image following the real-time image is added is displayed in a region outside the real-time image. If the additional image is not stored in the built-in memory, the X and Y direction moving means are operated to move the sample stage in the X and Y directions, and the required additional image signal is stored in the built-in memory. After that, it is preferable to return the sample stage to the initial position.
- the control device In a state where the wide-field buffer image is displayed on the display surface of the display means, when a finger is brought into contact with the touch screen, the control device displays the wide-field buffer image signal.
- the finger When the finger is moved without being detached from the touch screen, the wide-field buffer image is moved on the display surface of the display unit according to the movement of the finger, and the X and X It is preferable to operate the Y direction driving means to move the sample stage in the X and / or Y direction.
- control means operates the Z-direction driving means based on the contrast at the same position and the vicinity thereof.
- the focusing of the objective lens positioned at the working position with respect to the sample on the sample table is performed.
- the control means when a specific gesture of an operator's finger is applied to the touch screen, the control means is preferably set to a Raman measurement region setting mode.
- the specific gesture is to keep the finger in contact for a predetermined time, and it is convenient for the control means to set a region where the finger is in contact as a measurement region.
- the control means sets the measurement area corresponding to the movement of the finger. Is preferred.
- the control means is configured to move the Z direction driving means according to the parallel movement amount of the two fingers. It is preferable to move the material stage relative to the revolver in the Z direction by actuating.
- the control means relatively moves the sample stage in a direction approaching the revolver, and the two fingers are parallel in opposite directions. When moved, the control means moves the sample stage in a direction away from the revolver.
- the control means sets the relative position of the sample stage with respect to the revolver on the display means.
- a scale for indication and a sample stage indicator are displayed and the sample stage indicator is moved along the scale in response to relative movement of the sample stage relative to the revolver.
- the scale and the sample stage mark are displayed for a predetermined time, and when the scale and the sample stage mark are displayed, a finger is brought into contact with the sample stage mark and moved along the scale. It is preferable that the sample stage is moved relative to the revolver according to the movement of the finger.
- the control means actuates the Z direction drive to move the sample stage relative to the revolver to a position separated by a predetermined distance.
- the laser light source is energized when the wireless connection is disconnected against the user's intention while the touch screen is wirelessly connected to the control means.
- the control means de-energizes the laser light source.
- FIG. 1 is a simplified block diagram illustrating a preferred embodiment of a microscope configured in accordance with the present invention.
- 2 is a flowchart showing a basic operation control mode in the microscope shown in FIG. 1.
- the flowchart which shows an operation
- the flowchart which shows the sample stage movement and image update style in the microscope shown in FIG.
- the flowchart which shows the magnification change mode in the microscope illustrated in FIG.
- FIG. 2 is a simplified diagram showing an example of a wide-field buffer image displayed on display means in the microscope of FIG. 1.
- the schematic diagram which shows the scale for showing the raising / lowering position of a sample stage, and a sample stage label
- FIG. 1 schematically shows the main components of a Raman microscope constructed according to the present invention.
- the illustrated Raman microscope includes a sample stage 4 on which the sample 2 is placed.
- the sample stage 4 is mounted so as to be movable in the X direction (left and right direction in FIG. 1), Y direction (direction perpendicular to the paper surface in FIG. 1), and Z direction (up and down direction in FIG. 1).
- the sample stage 4 is provided with driving means 6, and the operation of the driving means 6 allows the sample stage 4 to be appropriately moved in the X direction, the Y direction, and the Z direction.
- the driving means 6 constitutes X and Y direction driving means for driving the sample stage 4 in the X direction and Y direction, and also constitutes a Z direction driving means for driving the sample stage 4 in the Z direction.
- a revolver 10 is rotatably mounted above the sample stage 4.
- the revolver 10 has a plurality of objective lenses 8 having different magnifications, for example, four objectives having magnifications of 5, 10, 20, and 50.
- a lens 8 is provided (only one of them is shown in FIG. 1).
- the revolver 10 is provided with a revolver driving means 12. When the revolver driving means 12 appropriately rotates the revolver 10, a predetermined one of the plurality of objective lenses 8 faces the sample stage 4. Positioned at the working position. In the illustrated embodiment, the sample stage 4 is appropriately moved in the Z direction as described above, and the Z direction interval between the objective lens 8 and the sample 2 on the sample stage 4 is appropriately set. In place of or in addition to moving the sample stage 4 in the Z direction, the revolver 10 is appropriately moved in the Z direction to appropriately set the Z direction interval between the objective lens 8 and the sample 2 on the sample stage 4. You can also.
- the illustrated Raman microscope includes a laser light source 14, a beam expander 16, a Y direction operation means 18, a lens 20, an aperture 24, a lens 26, a beam splitter 28, an X direction operation mirror 30, a lens 32, a lens 34, a lens 40, A spectroscope 46 having an entrance slit 44 and a Raman signal detector 48 which can be constituted by a CCD camera are arranged.
- the specific configuration and operation of these components in the illustrated Raman microscope are disclosed in detail in the specification and drawing (especially FIG. 1) of Japanese Patent Application Laid-Open No. 2007-179002. The description is omitted.
- the beam splitter 50 is disposed between the lens 40 and the revolver 10, and the lens 52 and the imaging unit 54 are disposed in association with the beam splitter 50.
- the beam splitter 50 and the lens 52 constitute image projection optical means for projecting the image of the sample 2 on the sample stage 4 to the imaging means 54 via the objective lens 8 positioned at the working position.
- the imaging means 54 can be composed of a CCD camera.
- the imaging means 54 is connected to the control means 56 together with the Raman signal detector 48.
- a display means 58 is attached to the control means 56 that can be constituted by a computer with a built-in memory.
- the display means 58 can be composed of an appropriate display such as a liquid crystal panel. It is important that a touch screen 60 for detecting the contact of the operator's finger is disposed on the display surface of the display means 58.
- the control means 56 controls various operations of the microscope in accordance with the gesture of the operator's finger applied to the touch screen 60. This is very important. Transmission and reception of signals between the control means 56 and various components of the microscope can be performed via appropriate signal lines. If desired, signals can be transmitted and received wirelessly.
- the description will be continued with reference to the flowchart shown in FIG. 2 together with FIG. 1.
- initialization is performed in the turning-on step n-1, and the microscope is set in advance. It will be in the initial state.
- an image projected on the imaging means 54 in step n-2 that is, a real-time image is displayed on the display surface of the display means 58.
- step n-3 it is determined whether or not a finger gesture of the operator is applied to the touch screen 60.
- the process proceeds to step n-4, and the operation control according to the gesture is performed as described in detail below.
- step n-5 it is determined whether or not the operation control corresponding to the gesture has ended.
- total magnification which means the magnification at which the sample on the sample stage 4 is displayed on the display surface of the display means 58, is expressed by the following equation.
- Total magnification (Magnification of objective lens 8) ⁇ (Magnification of image projection optical means)
- X (digital zoom magnification) x (ratio between the image area size of the image pickup means 54 and the display surface size of the display means 58)
- digital zoom magnification is the ratio between the entire image from the imaging means 54 and the portion actually displayed on the display surface of the display means 58, and when the magnification is 1, the entire image from the imaging means 54.
- a part of the image from the imaging unit 54 is enlarged and displayed on the display surface of the display unit 58 when the magnification is larger than 1, and when the magnification is smaller than 1, the display of the display unit 58 is displayed.
- the image from the imaging means 54 is smaller than the surface.
- step s-1 a gesture applied to the touch screen 60 is determined. If the gesture is a drag, the process proceeds to step s-2 to move the sample stage 4, and if the gesture is a pinch-in or pinch-out, the process proceeds to step s-3 to change the magnification. If the gesture is a double tap, the process proceeds to step s-4 to perform focusing (autofocus) of the objective lens 8, and if the gesture is a tap and hold, the process proceeds to step s-5 to set a measurement region. If the gesture is a double drag, the process moves to step s-6 and the sample stage is moved up and down.
- step t-1 the image signal from the imaging unit 54 is the control unit 56 in step t-1.
- the memory image based on the stored image signal is displayed on the display surface of the display means 58.
- step t-2 the movement distance of the finger is calculated.
- step t-3 the memory image displayed on the display surface of the display means 58 is moved by the movement distance of the finger, and the movement of the sample stage 4 is started.
- step t-4 it is determined whether or not the finger has been removed from the touch screen 60, that is, whether or not the drag has ended.
- step t-5 it is determined whether or not the sample stage 4 has been moved over a distance corresponding to the movement distance of the finger. If the required movement of the sample stage 4 is not completed, the process returns to step t-2. In this way, without waiting for the completion of the movement of the sample stage 4, the movement distance of the finger is repeatedly detected at predetermined time intervals to update the movement distance of the sample stage 4. Therefore, compared with the case where the next movement is started after waiting for the completion of the movement of the sample stage 4 (as disclosed in Patent Documents 1 and 2), the sample stage 4 is moved continuously without waiting time. The measurement site can be searched quickly.
- step t-6 the image signal stored in the built-in memory of the control means 56 is updated to the image signal from the imaging means 54. Accordingly, the image signal stored in the internal memory is also updated at predetermined time intervals.
- step t-7 the process proceeds to step t-7 and waits for the sample stage 4 to move over a distance corresponding to the movement distance of the finger before displaying on the display means 58. The image displayed on the screen is switched from the memory image to the real-time image.
- the memory image is superimposed on the real-time image, for example, translucent. It can also be displayed in the state.
- step x-1 the interval between two fingers brought into contact with the touch screen 60 is stored.
- step x-2 the process proceeds to step x-2, and when the interval between two fingers is changed (pinch-in or pinch-out), a reduction rate or enlargement rate of the interval is calculated, and according to the calculated reduction rate or enlargement rate
- the image signal from the imaging means 54 is reduced or enlarged and displayed on the display surface of the display means 58.
- the reduction ratio or the enlargement ratio exceeds the threshold value, the rotation of the revolver 10 is started and the replacement of the objective lens 8 positioned at the operation position is started. As shown in FIG.
- step x-3 it is determined whether or not replacement of the objective lens 8 has started. If the replacement of the objective lens 8 has not been started, the process proceeds to step x-4, where it is determined whether the pinch-in or pinch-out has been completed and the two fingers have been detached from the touch screen 60.
- step x-2 determines whether or not the objective lens 8 has been exchanged. If the objective lens 8 has been exchanged, the process proceeds to step x-6, and after the exchange of the objective lens 8 is completed, the image displayed on the display surface of the display means 58 is switched to a real-time image.
- step x-3 the replacement of the objective lens 8 is started in step x-3, the process proceeds to step x-7, and the image signal from the imaging means 54 at the start of replacement of the objective lens 8 is stored in the built-in memory of the control means 56.
- step x-8 determine whether or not the replacement of the objective lens 8 is completed. It is determined whether or not the replacement of the objective lens 8 has been completed. If the replacement of the objective lens 8 has not been completed, the process proceeds to step x-4. When the replacement of the objective lens 8 is completed, the process proceeds to step x-9.
- step x-9 the sample stage 4 is moved in the Z direction and the X and Y directions based on the same focal length error and the visual field center position error stored in advance in the built-in memory of the control means 56.
- the focus is adjusted, and the image on the display surface of the display means 58 is switched to a real-time image. Thereafter, the process proceeds to step x-4.
- Magnification change when the digital zoom magnification is smaller than 1 will be described as follows.
- the image size based on the image signal from the imaging unit 54 becomes smaller than the size of the display surface of the display unit 58.
- a wide-field buffer image obtained by adding the required additional images B1 to B8 to the outer area of the display image A based on the image signal from the imaging unit 54 on the display surface of the display unit 58. indicate.
- the real-time image display is stopped, and the image displayed on the display surface of the display means 58 is displayed as a wide-field buffer image (that is, an additional image adjacent thereto is displayed around the real-time image). Switch to the image to be displayed.
- the memory image is displayed in the center, and the portion where the additional image signal is not acquired in the surrounding area is gray, for example.
- step y-2 the image reduction rate (or enlargement rate) by pinch-in (or pinch-out when the digital zoom magnification is already smaller than 1) is calculated in the same manner as described above.
- step y-3 the memory image is reduced at the required reduction ratio (or enlarged at the required enlargement ratio) and displayed.
- step y-4 it is determined whether there is an unacquired area of an additional image to be displayed around the memory image. If an unacquired area exists, the process proceeds to step y-5.
- step y-5 the additional image signal from the imaging unit 54 is stored so that the image of the area adjacent to the memory image is projected onto the imaging unit 54 by appropriately moving the sample stage 4, and the stored memory is added.
- step y-6 the pinch-in (or pinch-out), that is, the two fingers touch the touch screen 60 It is discriminated whether or not the vehicle has been left. If the pinch-in (or pinch-out) has not ended, the process returns to step y-2. When the pinch-in (or pinch-out) is completed, the process proceeds to step y-7.
- step y-7 the sample stage 4 is returned to the state where the memory image is located at the center of the display surface of the display means 58, and after the completion of the return of the sample stage 4, the image of the central region of the wide-field image is displayed. To the real-time image.
- step z-1 the image signal from the imaging means 54 is stored in the built-in memory of the control means 56, and real-time image display is performed.
- the image displayed on the display surface of the display means 58 is stopped and switched to the wide-field buffer image.
- step z-2 the movement distance of the finger is calculated.
- step z-3 the wide-field buffer image is moved according to the movement distance of the finger.
- step z-4 it is determined whether or not there is an unacquired area of an additional image to be displayed around the memory image.
- step z-5 the additional image signal from the imaging unit 54 is stored so that the image of the region adjacent to the memory image is projected onto the imaging unit 54 by appropriately moving the sample stage 4, and the stored memory is added. The image is displayed on a required part on the display surface of the display means 58. This operation is repeated for all the additional images required around the central memory image, and thus the wide-field buffer image is displayed on the display surface of the display means 58.
- step z-6 the finger has been removed from the touch screen 60, that is, whether the drag has ended.
- step z-7 the sample stage 4 is moved so that the image from the imaging means 54 is located at the center of the display surface of the display means 58, and the wide-field image is waited for the movement of the sample stage 4 to be completed. Switch the image in the center area to real-time image.
- the control means 56 is provided with an objective lens for the sample 2 on the sample stage 4.
- Perform 8 focusing autofocus. This focusing can be performed on the basis of, for example, detecting the position where the finger is in contact and the contrast in the vicinity thereof, and the contrast.
- a laser beam can be irradiated to the position where the finger is in contact, and focusing can be performed based on the contrast of a required region of the sample 2 in the state where the laser beam is irradiated.
- a specific gesture of a finger is applied to the touch screen 60, for example, the finger is brought into contact and maintained for a predetermined time (touch).
- the control means 56 sets the Raman measurement area setting mode.
- the Raman measurement region is set according to the finger gesture applied to the touch screen 60.
- the position where the finger is in contact can be set as the Raman measurement region.
- the Raman measurement region can be set according to this movement. For example, when a finger that is in contact is dragged, a rectangular region having diagonal points between the initial contact position and the final drag position can be set as the measurement region.
- the image is moved while updating the wide-field buffer image as described above, and the objective lens with the lowest magnification is moved.
- An area wider than the visual field can be set as the measurement area.
- the finger is moved so as to surround the required area, the surrounded required area can be set as the Raman measurement area.
- step m-1 the distance between the two fingers in contact with the touch screen 60 is stored.
- step m-2 the distance between the two fingers is moved without being substantially changed (if the distance between the two fingers is changed, the process proceeds to step x-2 shown in FIG. 5).
- the direction of movement (up or down) and the amount of movement are detected.
- Step m-3 the scale 62 and the sample stage indicator 64 as shown in FIG. 11 are displayed over a predetermined time on one side of the display means 58, for example.
- the sample stage indicator 64 indicates the vertical position of the sample stage 4, and the scale 62 indicates the vertical interval between the revolver 10 and the sample stage 4.
- the driving means 6 is operated in accordance with the parallel movement of the two fingers to move the sample stage 4 up and down. More specifically, when two fingers are translated in a predetermined direction, that is, upward, the sample stage 4 is raised, and when two fingers are translated in the opposite direction, that is, downward, the sample stage 4 is moved. Move down. The vertical position of the sample stage 4 is detected by appropriate detection means (not shown), and the sample stage indicator 64 is moved up and down along the scale 62 as the sample stage 4 is moved up and down.
- step m-5 it is determined whether or not the parallel movement of the two fingers is completed and the two fingers are detached from the touch screen 60. If the parallel movement has not been completed, the process returns to step m-2. In a state where the scale 62 and the sample stage indicator 64 are displayed on the display means 58, the sample stage 4 may be moved up and down by bringing the sample stage indicator 64 up and down by bringing the finger into contact with the sample stage indicator 64. it can.
- the touch screen 60 and the control means 56 can be connected wirelessly.
- the control means 56 automatically moves the sample stage 4 when the revolver 10 and the sample stage 4 are approaching over a predetermined distance when the wireless connection is disconnected against the user's intention. It is desirable that the sample stage 4 is lowered by a predetermined distance from the revolver 10 to ensure safety. If the laser light source 14 is energized, it is desirable to deenergize it.
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Abstract
Description
該制御手段は、該タッチスクリーンに適用される操作者の指のジェスチャに応じて、該X及びY方向駆動手段の作動、該Z方向駆動手段の作動、該レボルバ駆動手段の作動、及び該表示手段における表示倍率を制御する、ことを特徴とする顕微鏡が提供される。
(総合倍率)=(対物レンズ8の倍率)×(画像投射光学手段の倍率)
×(デジタルズーム倍率)×(撮像手段54の画像領
域寸法と表示手段58の表示面寸法との比)
尚、語句「デジタルズーム倍率」は撮像手段54からの画像全体と表示手段58の表示面上に実際に表示される部分との比であって、倍率1の場合には撮像手段54からの画像全体が表示され、倍率が1よりも大きい場合には撮像手段54からの画像の一部が拡大されて表示手段58の表示面に表示され、倍率が1よりも小さい場合には表示手段58の表示面よりも撮像手段54からの画像が小さくなる。
4:試料ステージ
6:駆動手段(X及びY方向駆動手段、Z方向駆動手段)
8:対物レンズ
10:レボルバ
12:レボルバ駆動手段
54:撮像手段
56:制御手段
58:表示手段
60:タッチスクリーン
Claims (20)
- X及びY方向に移動自在に装着された試料ステージ、該試料ステージをX及びY方向に駆動するX及びY方向駆動手段、倍率が異なった複数個の対物レンズを含むレボルバ、該試料ステージと該レボルバとをZ方向に相対的移動せしめるためのZ方向駆動手段、該複数個の対物レンズのうちの任意の1個を選択的に該試料ステージに対向する作用位置に位置付けるためのレボルバ駆動手段、撮像手段、該試料ステージ上に位置せしめられた試料の画像を該作用位置に位置付けられた対物レンズを通して該撮像手段に投射する画像投射光学手段、表示手段、該表示手段の表示面上に配設されたタッチスクリーン、及び制御手段を具備する顕微鏡にして、
該制御手段は、該タッチスクリーンに適用される操作者の指のジェスチャに応じて、該X及びY方向駆動手段の作動、該Z方向駆動手段の作動、該レボルバ駆動手段の作動、及び該表示手段における表示倍率を制御する、ことを特徴とする顕微鏡。 - 該タッチスクリーンに1本の指が当接されると、該制御装置は、該撮像手段からの画像信号を内蔵メモリに保存し、該表示手段の表示面上に保存した画像信号に基づくメモリ画像を表示せしめ、指が該タッチスクリーンから離脱されることなく移動されると、指の移動に応じて該表示手段の表示面上において該メモリ画像を移動せしめると共に、該X及びY方向駆動手段を作動せしめて該試料ステージをX及び/又はY方向に移動せしめる、請求項1記載の顕微鏡。
- 該制御手段は、該タッチスクリーンに指が当接されてから該タッチスクリーンから指が離脱されるまで、所定時間間隔で指の移動を検出し指の位置に基いて該メモリ画像を更新し、そして指の移動が停止されて指が該タッチスクリーンから離脱され、該試料ステージの移動が終了すると、該表示手段の表示面上に表示される画像を該撮像手段に投射されているリアルタイム画像にせしめる、請求項2記載の顕微鏡。
- 該タッチスクリーンに2本の指が同時に当接されると、該制御手段は、2本の指の間隔を記憶し、該タッチスクリーンから2本の指が離脱されることなく2本の指の間隔が変化せしめられると、該制御手段は、2本の指の間隔の変化率に応じて該表示手段の表示面上に表示される画像の倍率を変化せしめる、請求項1から3までのいずれかに記載の顕微鏡。
- 2本の指の間隔の変化率が所定閾値を越えると、該制御手段は、該レボルバ駆動手段を作動せしめて該試料ステージに対向する該作用位置に位置する対物レンズを変更する、請求項4記載の顕微鏡。
- 該レボルバ駆動手段の作動を開始する際には、該制御手段は、該撮像手段からの画像信号を該内蔵メモリに保存し、該レボルバ駆動手段の作動中においては該表示手段の該表示面上には該内臓メモリに保存した画像信号に基づくメモリ画像を2本の指の変化率に応じた倍率で表示せしめる、請求項5記載の顕微鏡。
- 対物レンズの変更が終了すると、該制御手段は、該内蔵メモリに予め保存した同焦点距離及び視野中心位置に関する情報に基いて、該X方向及びY方向駆動手段及び/又は該Z方向駆動手段を作動せしめてピント調整し、しかる後に該表示手段の表示面上に表示される画面を該撮像手段に投射されているリアルタイム画像にせしめる、請求項5又は6記載の顕微鏡。
- 最低倍率の対物レンズが作用位置に位置せしめられた後に該表示手段の該表示面上に表示される画像が縮小された場合、該制御手段は、該表示手段の該表示面上におけるリアルタイム画像の外側の領域にリアルタイム画像に続く追加画像が付加された広視野バッファ画像を表示せしめる、請求項1から7までのいずれかに記載の顕微鏡。
- 該追加画像が該内蔵メモリに記憶されていない場合には、該X及びY方向移動手段を作動せしめて該試料ステージをX及びY方向に移動して所要追加画像信号を該内蔵メモリに保存し、しかる後に該試料ステージを初期位置に戻す、請求項8記載の顕微鏡。
- 該表示手段の該表示面上に該広視野バッファ画像が表示せしめられている状態において、該タッチスクリーンに1本の指が当接されると、該制御装置は、該広視野バッファ画像信号を該内蔵メモリに保存し、指が該タッチスクリーンから離脱されることなく移動されると、指の移動に応じて該表示手段の表示面上において該広視野バッファ画像を移動せしめると共に、該X及びY方向駆動手段を作動せしめて該試料ステージをX及び/又はY方向に移動せしめる、請求項8又は9記載の顕微鏡。
- 該タッチスクリーンの同位置に指が2回続けて当接されると、該制御手段は、該同位置及びその近傍のコントラストに基づいて該Z方向駆動手段を作動せしめて、該試料テーブル上の試料に対して作用位置に位置付けられている対物レンズの焦点合わせを遂行する、請求項1から10までのいずれかに記載の顕微鏡。
- ラマン顕微鏡であり、該タッチスクリーンに操作者の指の特定のジェスチャが適用されると、該制御手段は、ラマン測定領域設定モードに設定する、請求項1から11までのいずれかに記載の顕微鏡。
- 該特定のジェスチャは指を当接せしめて所定時間維持することであり、該制御手段は、指が当接された部位を測定領域として設定する、請求項12記載の顕微鏡。
- 該測定領域設定モードに設定された後に、該タッチスクリーンに指が当接され該タッチスクリーンから離脱されることなく移動されると、該制御手段は指の移動に対応して測定領域を設定する、請求項12記載の顕微鏡。
- 該タッチスクリーンに2本の指が同時に当接され、該タッチスクリーンから離脱されることなく平行移動せしめられると、該制御手段は、2本の指の平行移動量に応じて該Z方向駆動手段を作動せしめて該レボルバに対して該資料ステージをZ方向に相対的に移動せしめる、請求項1から14までのいずれかに記載の顕微鏡。
- 2本の指が所定方向に平行移動せしめられると、該制御手段は、該レボルバに対して接近する方向に該試料ステージを相対的に移動せしめ、2本の指が反対方向に平行移動せしめられると、該制御手段は、該レボルバに対して離隔する方向に該試料ステージを移動せしめる、請求項15記載の顕微鏡。
- 該タッチスクリーンに2本の指が同時に当接され、該タッチスクリーンから離脱されることなく平行移動せしめられると、該制御手段は、該表示手段上に該レボルバに対する該試料ステージの相対的位置を示すための尺度と試料ステージ標識とを表示し、該レボルバに対する該試料ステージに相対的移動に応じて該試料ステージ標識を該尺度に沿って移動せしめる、請求項15または16記載の顕微鏡。
- 該尺度と該試料ステージ標識とが所定時間に渡って表示され、該尺度と該試料ステージ標識とが表示されている時に、該試料ステージ標識に指を当接せしめて該尺度に沿って移動せしめると、指の移動に応じて該レボルバに対して該試料ステージが相対的に移動せしめられる、請求項15から17までのいずれかに記載の顕微鏡。
- 該タッチスクリーンが無線で該制御手段に接続されている状態において、使用者の意図に反して無線接続が切断された時に、該レボルバに対して該試料ステージが所定距離を超えて接近している場合には、該制御手段は、該Z方向駆動を作動せしめて該レボルバに対して該試料ステージを所定距離離隔した位置に相対的に移動せしめる、請求項1から18までのいずれかに記載の顕微鏡。
- レーザ光源を備えており、該タッチスクリーンが無線で該制御手段に接続されている状態において、使用者の意図に反して無線接続が切断された時に該レーザ光源が付勢されている場合には、該制御手段は、該レーザ光源を除勢する、請求項1から19までのいずれかに記載の顕微鏡。
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