WO2012046649A1 - 薬剤供給装置 - Google Patents
薬剤供給装置 Download PDFInfo
- Publication number
- WO2012046649A1 WO2012046649A1 PCT/JP2011/072554 JP2011072554W WO2012046649A1 WO 2012046649 A1 WO2012046649 A1 WO 2012046649A1 JP 2011072554 W JP2011072554 W JP 2011072554W WO 2012046649 A1 WO2012046649 A1 WO 2012046649A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- leveling
- supply device
- leveling tool
- powder
- medicine supply
- Prior art date
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/06—Containers or packages with special means for dispensing contents for dispensing powdered or granular material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B37/00—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
- B65B37/16—Separating measured quantities from supply
- B65B37/20—Separating measured quantities from supply by volume measurement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B65/00—Details peculiar to packaging machines and not otherwise provided for; Arrangements of such details
-
- G—PHYSICS
- G07—CHECKING-DEVICES
- G07F—COIN-FREED OR LIKE APPARATUS
- G07F17/00—Coin-freed apparatus for hiring articles; Coin-freed facilities or services
- G07F17/0092—Coin-freed apparatus for hiring articles; Coin-freed facilities or services for assembling and dispensing of pharmaceutical articles
Definitions
- This invention relates to the chemical
- a medicine supply device including a powder distribution unit is provided in a medicine packaging machine or the like.
- This medicine supply apparatus is for distributing and supplying a powder of the medicine. For example, what was described in patent document 1 by the applicant of this application is mentioned.
- This powder distribution part has a powder receiving groove whose longitudinal sectional view is V-shaped. An operator such as a pharmacist puts the powder into the powder receiving groove. The charged powder falls to a divider provided below the powder receiving groove. Thereby, a powder is divided
- the surface of the powder put into the powder receiving groove by the worker is raised or recessed immediately after the addition. If the height of the powder surface varies, the powder cannot be divided evenly, so it is necessary to level the surface.
- a leveling tool such as a spatula is attached to the drug supply device. The operator holds this leveling tool and scrapes the surface of the powder so that the surface is even.
- the leveling tool In the conventional medicine supply device, there is no place for holding the leveling tool. Therefore, a leveling tool has been placed around the medicine supply device at the operator's discretion. At that time, a case such as a brush case was sometimes used as a case for a leveling tool.
- the upper cover of the medicine supply device can be opened and closed for maintenance or the like. For this reason, when the leveling tool is placed on the upper cover, the leveling tool may be dropped on the floor or the like when the upper cover is opened.
- the relationship between the drug supply device and the place where the leveling tool is placed has not been established. For this reason, the leveling tool may be lost, or it is necessary to search for the leveling tool every time the leveling work is performed.
- an object of the present invention is to provide a medicine supply device that can quickly take out a leveling tool when an operator needs it and has good workability.
- the present invention is a drug supply device including a powder distribution unit that stores and distributes powder, and the drug supply device includes a leveling tool for leveling the surface of the stored powder, and the leveling tool. And a leveling tool holding part.
- the leveling tool can be held in the medicine supply device. For this reason, it is difficult to lose the leveling tool, and it is not necessary to search for the leveling tool every time the operator performs the leveling work.
- maintenance part can be made to be provided in the vicinity of the said powder distribution part, and the front side of a chemical
- the leveling tool can be held in the vicinity of the powder distribution unit and on the front side of the drug supply device. For this reason, the distance which an operator takes out a leveling tool from a leveling tool holding
- the leveling tool holding part includes a base part attached to the main body of the medicine supply device and a lid part that can be opened and closed with respect to the base part. It is equipped with an internal space that can be arranged in parallel.
- the leveling tool is arranged in the internal space between the base and the lid. For this reason, it is hygienic. And since several leveling tools are arrange
- the lid portion includes a support surface that supports a leveling tool disposed in the internal space.
- a plurality of leveling tools are arranged in the inner space so as to be arranged in the lateral direction of the leveling tools.
- the leveling tool includes a leveling part for leveling the powder at at least one end of the rod-shaped gripping part, and the leveling tool holding part does not interfere with the leveling part.
- a recess is provided.
- the medicine supply device includes an upper cover that can be opened and closed, and the leveling tool holding portion also serves as a handle for opening the upper cover.
- the support surface has a step for supporting a plurality of leveling tools.
- a supply device can be provided.
- FIG. 1 is a perspective view of a medicine packaging device provided with a leveling tool holder of the present embodiment, as viewed from the front side (front side), omitting the internal mechanism.
- FIG. 2 is a perspective view showing the leveling tool holder.
- FIG. 3 is a perspective view showing a state in which the lid of the leveling tool holder is opened.
- FIG. 4 is a perspective view showing the lid portion of the leveling tool holding portion as seen from the back side (rear side).
- FIG. 5 is a perspective view showing the lid of the leveling tool holding part, as seen from the back side (rear side), and FIG. 5 (A) shows a state where one leveling tool is placed. (B) shows a state where two leveling tools are placed.
- upper and lower means the positional relationship in the state shown in FIG. 1
- front means the front side in the state shown in FIG. 1
- rear Means the back side.
- expression in this direction is used for convenience of explanation, and is not used for limiting the invention.
- the drug supply device 100 of the present embodiment is as shown in FIG. 1 and includes a powder distribution unit 101a in front of the upper surface of the main body 101. An operator puts the powder into the powder distribution unit 101a.
- the “main body” refers to a portion of the medicine supply device 100 excluding the leveling tool holder 1.
- the leveler holding part 1 of the present embodiment is a box-like one provided in the main body 101 of the medicine supply device as shown in FIG.
- a plurality of leveling tools S... S can be stored in the leveling tool holding portion 1.
- the dimension in the width direction of the leveling tool holder 1 is slightly larger than the length dimension of the leveling tool S, and the leveling tool S can be stored with a margin.
- the leveler holding unit 1 is provided in the vicinity of the powder distribution unit 101a and on the front surface of the main body 101 of the medicine supply device. Since the leveling tool holding unit 1 is provided in such a positional relationship, the operator takes out the desired leveling tool S from the leveling tool holding unit 1 and immediately performs leveling work in the powder distribution unit 101a. It can be performed.
- the leveling tool holder 1 is provided on the front surface of the main body 101 of the medicine supply device.
- it may be provided inside the front door of the medicine supply device 100 and can be provided at various positions. .
- it is desirable to provide at a position closer to the upper side of the medicine supply device 100.
- the leveling tool holder 1 of this embodiment includes a base 2 attached to the main body 101 of the medicine supply device and a lid 3 that can be opened and closed with respect to the base 2.
- the lid 3 is rotatably supported at the lower part of the base 2. As shown in FIG. 3, this rotation is performed so that the lid 3 can be opened about 50 ° with respect to the base 2.
- An opening recess 21 is provided at the upper front of the base 2. The operator can easily open the lid portion 3 by inserting a finger into the opening recess 21. In the present embodiment, no means for closing the lid 3 is provided, and the lid 3 can be used with the lid 3 open.
- the base 2 or the lid 3 may be provided with a spring or the like, and the lid 3 may be automatically closed after the operator opens the lid 3.
- each magnet 22 of the base portion 2 attracts each attracting portion 35 of the lid portion 3 so that the closed state is maintained.
- the lid portion 3 may be unexpectedly opened unless the operator handles the lid portion 3 in order to open the lid portion 3. Hard to happen. In addition, it is difficult for dust to adhere to the leveling tool S.
- a notch 23 is formed at the center of the lower end of the base 2.
- the cutout portion 23 also serves as a handle for opening the upper cover provided with the powder distribution unit 101a and the like in the medicine supply device 100. The operator can open the upper cover by placing a hand on the notch 23.
- a plurality of leveling tools S ... S can be arranged in parallel in the internal space formed by the base 2 and the lid 3.
- “Parallel” here refers not to a relationship in which the leveling tools S... S are aligned in the longitudinal direction (vertical alignment) but to a relationship in which they are aligned in the lateral direction (horizontal alignment).
- two leveling tools Sa and Sb can be arranged in the leveling tool holding part 1 of the present embodiment so that the leveling parts S2 are parallel to each other.
- the leveling tool S used in the present embodiment has the shape shown in FIGS. 5A and 5B, and plate-shaped leveling portions S2 are provided at both ends of the rod-shaped gripping portion S1. .
- the operator can level the surface of the powder to an even height by scratching the surface of the powder charged in the powder distribution unit 101a of the medicine supply device with the leveling unit S2.
- leveling can be performed at the height of four patterns per leveling tool S.
- the leveling tool S provided with the leveling part S2 only at one end of the rod-shaped gripping part S1 may be used.
- the leveling tool S is supported by support surfaces 31 and 32 which are the inner lower surface of the lid 3. More specifically, as shown in FIGS. 5A and 5B, the gripping portion S1 of the leveling tool S is placed on the support surfaces 31 and 32.
- the first support surface 31 is formed one step above the second support surface 32, and there is a step between the support surfaces 31 and 32.
- One leveling tool Sa can be placed on the first support surface 31 and the other leveling tool Sb can be placed on the second support surface 32.
- FIG.3 and FIG.5 (B) one leveling tool Sa and the other leveling tool Sb can be put in steps. For this reason, the operator can easily take out one leveling tool S from among a plurality of levels stored in the leveling tool holder 1.
- a concave portion 33 is formed on both sides of the support surfaces 31 and 32 in the width direction. Thereby, the leveling part S2 of the leveling tool S does not interfere with the lid part 3.
- a notch 34 is formed at the center of the lower end of the lid 3. The notch 34 coincides with the notch 23 of the base 2 when the lid 3 is closed.
- the leveling tool holding part 1 of the present embodiment is box-shaped, and stores therein a plurality of leveling tools S ... S, but holds the leveling tools S ... S using various other means.
- the leveling tool holding part 1 can be obtained.
- pocket-shaped items holding by inserting
- hook-shaped items holding by hooking
- magnets holding by suction
- items by hook-and-loop fasteners holding by sticking
- fitting pinching by bands, etc.
- a tray-like thing (mounting) is mentioned.
- the support surfaces 31, 32 and the recess 33 may be provided on the base 2, and the leveling tool S may be supported on the base 2.
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Quality & Reliability (AREA)
- Chemical & Material Sciences (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Basic Packing Technique (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Abstract
Description
2 基部
3 蓋部
100 薬剤供給装置
101 薬剤供給装置の本体
101a 散剤分配部
S 均し具
Claims (8)
- 散剤を収容して分配する散剤分配部を備える薬剤供給装置であって、
前記薬剤供給装置は、前記収容された散剤の表面を均すための均し具と、前記均し具を保持する均し具保持部とを備える薬剤供給装置。 - 前記均し具保持部は、前記散剤分配部の近傍、かつ、薬剤供給装置の前面側に設けられる請求項1に記載の薬剤供給装置。
- 前記均し具保持部は、薬剤供給装置の本体に取り付けられる基部と、前記基部に対して開閉可能な蓋部とを備え、
前記基部と蓋部との間に、複数の均し具を並列して配置可能な内部空間を備える請求項1または2に記載の薬剤供給装置。 - 前記蓋部は、前記内部空間に配置された均し具を支持する支持面を備える請求項3に記載の薬剤供給装置。
- 前記内部空間には、複数の均し具が、当該均し具の短手方向に並ぶように配置される請求項3に記載の薬剤供給装置。
- 前記均し具は、棒状の把持部の少なくとも一端に、散剤を均すための均し部を備え、
前記均し具保持部は、前記均し部が干渉しないようにするための凹部を備える請求項3に記載の薬剤供給装置。 - 前記薬剤供給装置は、開閉可能な上部カバーを備え、
前記均し具保持部は、前記上部カバーを開けるための取手を兼ねる請求項3に記載の薬剤供給装置。 - 前記支持面は、複数の均し具を支持するための段差を有する請求項4に記載の薬剤供給装置。
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/821,201 US20130183079A1 (en) | 2010-10-05 | 2011-09-30 | Medicine supply apparatus |
EP11830581.2A EP2626309A1 (en) | 2010-10-05 | 2011-09-30 | Medicine supplying device |
KR1020137002049A KR20130125749A (ko) | 2010-10-05 | 2011-09-30 | 약제 공급 장치 |
CN2011800389442A CN103153796A (zh) | 2010-10-05 | 2011-09-30 | 药物供给装置 |
AU2011313419A AU2011313419A1 (en) | 2010-10-05 | 2011-09-30 | Medicine supplying device |
CA2811322A CA2811322A1 (en) | 2010-10-05 | 2011-09-30 | Medicine supply apparatus |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010225575A JP2012076816A (ja) | 2010-10-05 | 2010-10-05 | 薬剤供給装置 |
JP2010-225575 | 2010-10-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2012046649A1 true WO2012046649A1 (ja) | 2012-04-12 |
Family
ID=45927645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2011/072554 WO2012046649A1 (ja) | 2010-10-05 | 2011-09-30 | 薬剤供給装置 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20130183079A1 (ja) |
EP (1) | EP2626309A1 (ja) |
JP (1) | JP2012076816A (ja) |
KR (1) | KR20130125749A (ja) |
CN (1) | CN103153796A (ja) |
AU (1) | AU2011313419A1 (ja) |
CA (1) | CA2811322A1 (ja) |
WO (1) | WO2012046649A1 (ja) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0761402A (ja) | 1993-08-26 | 1995-03-07 | Takasono Sangyo Kk | 分包機 |
JPH0730927U (ja) * | 1993-11-11 | 1995-06-13 | 弘恵 鈴木 | しゃもじ収納装置を有する炊飯器 |
JPH08133201A (ja) * | 1994-11-09 | 1996-05-28 | Takazono Sangyo Kk | ホースフック |
JP2002096802A (ja) * | 2000-09-21 | 2002-04-02 | Ueda Avancer Corp | 秤量式全自動散薬分割方法、秤量式全自動散薬分割装置及び秤量式全自動散薬分割分包装置 |
JP2003334235A (ja) * | 2003-03-31 | 2003-11-25 | Munekuni Machiya | 匙機能付均しへら |
JP2009189718A (ja) * | 2008-02-18 | 2009-08-27 | Takazono Sangyo Co Ltd | 薬剤分包機 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1903936A (en) * | 1930-09-27 | 1933-04-18 | Raymond B Nunnery | Display rack |
US3271860A (en) * | 1965-05-07 | 1966-09-13 | William E Burton | Cabinet having sterilizable instrument tray |
FR2596299B1 (fr) * | 1986-03-27 | 1989-08-11 | Cga Hbs | Procede de confection de lots de petits elements et installation de mise en oeuvre |
US20030015447A1 (en) * | 2001-07-20 | 2003-01-23 | Chao-Yang Huang | Tool box |
US6767200B2 (en) * | 2001-09-28 | 2004-07-27 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
GB0202912D0 (en) * | 2002-02-07 | 2002-03-27 | Meridica Ltd | Method and apparatus for introducing powder into a pocket |
US20030201697A1 (en) * | 2002-04-30 | 2003-10-30 | Richardson William R. | Storage device for health care facility |
US6964337B2 (en) * | 2002-07-16 | 2005-11-15 | Engle Patrick A | Gardening tool transport and storage device |
US20050236940A1 (en) * | 2004-04-22 | 2005-10-27 | Rockoff Mark A | Medical procedure cart and method of customizing the same |
US8534508B2 (en) * | 2006-10-10 | 2013-09-17 | Jerry Dwight Bush | Storage dispenser apparatus for aids, consumables and utensils |
TWM381498U (en) * | 2009-11-25 | 2010-06-01 | Hou-Fei Hu | Tool box with a through hole |
US20120325695A1 (en) * | 2010-08-11 | 2012-12-27 | All About Packaging Inc. | Magnetic storage device |
-
2010
- 2010-10-05 JP JP2010225575A patent/JP2012076816A/ja active Pending
-
2011
- 2011-09-30 CN CN2011800389442A patent/CN103153796A/zh active Pending
- 2011-09-30 WO PCT/JP2011/072554 patent/WO2012046649A1/ja active Application Filing
- 2011-09-30 CA CA2811322A patent/CA2811322A1/en not_active Abandoned
- 2011-09-30 US US13/821,201 patent/US20130183079A1/en not_active Abandoned
- 2011-09-30 AU AU2011313419A patent/AU2011313419A1/en not_active Abandoned
- 2011-09-30 KR KR1020137002049A patent/KR20130125749A/ko not_active Application Discontinuation
- 2011-09-30 EP EP11830581.2A patent/EP2626309A1/en not_active Withdrawn
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0761402A (ja) | 1993-08-26 | 1995-03-07 | Takasono Sangyo Kk | 分包機 |
JPH0730927U (ja) * | 1993-11-11 | 1995-06-13 | 弘恵 鈴木 | しゃもじ収納装置を有する炊飯器 |
JPH08133201A (ja) * | 1994-11-09 | 1996-05-28 | Takazono Sangyo Kk | ホースフック |
JP2002096802A (ja) * | 2000-09-21 | 2002-04-02 | Ueda Avancer Corp | 秤量式全自動散薬分割方法、秤量式全自動散薬分割装置及び秤量式全自動散薬分割分包装置 |
JP2003334235A (ja) * | 2003-03-31 | 2003-11-25 | Munekuni Machiya | 匙機能付均しへら |
JP2009189718A (ja) * | 2008-02-18 | 2009-08-27 | Takazono Sangyo Co Ltd | 薬剤分包機 |
Also Published As
Publication number | Publication date |
---|---|
CA2811322A1 (en) | 2012-04-12 |
EP2626309A1 (en) | 2013-08-14 |
KR20130125749A (ko) | 2013-11-19 |
JP2012076816A (ja) | 2012-04-19 |
AU2011313419A1 (en) | 2013-03-28 |
CN103153796A (zh) | 2013-06-12 |
US20130183079A1 (en) | 2013-07-18 |
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