WO2012005561A3 - Способ масс- спектрометрии и устройство для его осуществления - Google Patents

Способ масс- спектрометрии и устройство для его осуществления Download PDF

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Publication number
WO2012005561A3
WO2012005561A3 PCT/KZ2011/000011 KZ2011000011W WO2012005561A3 WO 2012005561 A3 WO2012005561 A3 WO 2012005561A3 KZ 2011000011 W KZ2011000011 W KZ 2011000011W WO 2012005561 A3 WO2012005561 A3 WO 2012005561A3
Authority
WO
WIPO (PCT)
Prior art keywords
mass
flux
reflecting
substances
composition
Prior art date
Application number
PCT/KZ2011/000011
Other languages
English (en)
French (fr)
Other versions
WO2012005561A2 (ru
Inventor
Алдан Асанович САПАРГАЛИЕВ
Ербол Алданович САПАРГАЛИЕВ
Original Assignee
Saparqaliyev Aldan Asanovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saparqaliyev Aldan Asanovich filed Critical Saparqaliyev Aldan Asanovich
Priority to DE112011102315T priority Critical patent/DE112011102315T5/de
Priority to GB1301182.0A priority patent/GB2495667A/en
Priority to JP2013518291A priority patent/JP2013532366A/ja
Priority to CA2804968A priority patent/CA2804968A1/en
Priority to EP11803847.0A priority patent/EP2615622A4/en
Publication of WO2012005561A2 publication Critical patent/WO2012005561A2/ru
Publication of WO2012005561A3 publication Critical patent/WO2012005561A3/ru
Priority to US13/737,018 priority patent/US8598516B2/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
    • H01J49/408—Time-of-flight spectrometers with multiple changes of direction, e.g. by using electric or magnetic sectors, closed-loop time-of-flight
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
    • H01J49/405—Time-of-flight spectrometers characterised by the reflectron, e.g. curved field, electrode shapes
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
    • H01J49/406—Time-of-flight spectrometers with multiple reflections
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Optical Elements Other Than Lenses (AREA)

Abstract

Изобретение относится к электронной аналитической технике по определению состава и структуры веществ, в частности к области анализаторов, включающих в себя, по меньшей мере, один масс-спектрометр(М8), и может быть использовано, в медицине, в биологии, в газовой и нефтяной промышленности, в металлургии, энергетике, геохимии, гидрологии, экологии. Технический результат - увеличение разрешающей способности MS, чувствительности, точности и скорости измерения состава и структуры веществ, при одновременном расширении функциональных возможностей, уменьшении геометрических габаритов и массы анализаторов вещества. В способе масс-спектрометрии формирование ионного потока и управление им осуществляют однопоточным вне осевым методом; параллельно - многопоточным методом; методом использования трехмерного поля со средней меридианной поверхностью, в том числе отражающего трехмерного вида и отражающего двузонного вида или методом массивов многоотражения. Разработаны варианты устройств для реализации способа. Представлены принципиальные ионно-оптические схемы, которые позволяют создавать различные виды MS с меньшими материалоемкостью и геометрическими размерами
PCT/KZ2011/000011 2010-07-09 2011-07-08 Способ масс- спектрометрии и устройство для его осуществления WO2012005561A2 (ru)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE112011102315T DE112011102315T5 (de) 2010-07-09 2011-07-08 Verfahren der Massenspektrometrie und Einrichtung für seine Ausführung
GB1301182.0A GB2495667A (en) 2010-07-09 2011-07-08 Mass spectrometry method and devcie for implementing same
JP2013518291A JP2013532366A (ja) 2010-07-09 2011-07-08 質量分析法及びそれらの装置
CA2804968A CA2804968A1 (en) 2010-07-09 2011-07-08 A method of mass-spectrometry and a device for its realization
EP11803847.0A EP2615622A4 (en) 2010-07-09 2011-07-08 MASS SPECTROMETRY METHOD AND DEVICE FOR IMPLEMENTING IT
US13/737,018 US8598516B2 (en) 2010-07-09 2013-01-09 Method of mass-spectrometry and a device for its realization

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KZ2010/0907.1 2010-07-09
KZ20100907 2010-07-09

Publications (2)

Publication Number Publication Date
WO2012005561A2 WO2012005561A2 (ru) 2012-01-12
WO2012005561A3 true WO2012005561A3 (ru) 2012-03-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KZ2011/000011 WO2012005561A2 (ru) 2010-07-09 2011-07-08 Способ масс- спектрометрии и устройство для его осуществления

Country Status (7)

Country Link
US (1) US8598516B2 (ru)
EP (1) EP2615622A4 (ru)
JP (1) JP2013532366A (ru)
CA (1) CA2804968A1 (ru)
DE (1) DE112011102315T5 (ru)
GB (1) GB2495667A (ru)
WO (1) WO2012005561A2 (ru)

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WO2017089045A1 (en) * 2015-11-27 2017-06-01 Shimadzu Corporation Ion transfer apparatus
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US10319573B2 (en) 2017-01-26 2019-06-11 Protein Metrics Inc. Methods and apparatuses for determining the intact mass of large molecules from mass spectrographic data
US11626274B2 (en) 2017-08-01 2023-04-11 Protein Metrics, Llc Interactive analysis of mass spectrometry data including peak selection and dynamic labeling
US10546736B2 (en) 2017-08-01 2020-01-28 Protein Metrics Inc. Interactive analysis of mass spectrometry data including peak selection and dynamic labeling
US10510521B2 (en) 2017-09-29 2019-12-17 Protein Metrics Inc. Interactive analysis of mass spectrometry data
US11640901B2 (en) 2018-09-05 2023-05-02 Protein Metrics, Llc Methods and apparatuses for deconvolution of mass spectrometry data
WO2020071892A1 (ru) * 2018-10-04 2020-04-09 Алдан Асанович САПАРГАЛИЕВ Высокоразрешающая времяпролетная масс-спектрометрия
US11346844B2 (en) 2019-04-26 2022-05-31 Protein Metrics Inc. Intact mass reconstruction from peptide level data and facilitated comparison with experimental intact observation
TWI790459B (zh) * 2020-07-09 2023-01-21 立普思股份有限公司 紅外線人體辨識方法
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Also Published As

Publication number Publication date
CA2804968A1 (en) 2012-01-12
GB201301182D0 (en) 2013-03-06
WO2012005561A2 (ru) 2012-01-12
JP2013532366A (ja) 2013-08-15
EP2615622A2 (en) 2013-07-17
GB2495667A8 (en) 2013-10-23
EP2615622A4 (en) 2014-06-18
DE112011102315T5 (de) 2013-06-20
US20130161508A1 (en) 2013-06-27
GB2495667A (en) 2013-04-17
US8598516B2 (en) 2013-12-03

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