WO2011126332A3 - 크로마토그래피 질량분석을 이용한 인삼 연근 판별 방법 - Google Patents

크로마토그래피 질량분석을 이용한 인삼 연근 판별 방법 Download PDF

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Publication number
WO2011126332A3
WO2011126332A3 PCT/KR2011/002466 KR2011002466W WO2011126332A3 WO 2011126332 A3 WO2011126332 A3 WO 2011126332A3 KR 2011002466 W KR2011002466 W KR 2011002466W WO 2011126332 A3 WO2011126332 A3 WO 2011126332A3
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WO
WIPO (PCT)
Prior art keywords
ginseng
roots
age
ginseng roots
chromatography
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PCT/KR2011/002466
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English (en)
French (fr)
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WO2011126332A2 (ko
Inventor
이동호
김나현
김금옥
이재원
방경환
김영창
신유수
차선우
Original Assignee
고려대학교 산학협력단
대한민국(농촌진흥청장)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 고려대학교 산학협력단, 대한민국(농촌진흥청장) filed Critical 고려대학교 산학협력단
Publication of WO2011126332A2 publication Critical patent/WO2011126332A2/ko
Publication of WO2011126332A3 publication Critical patent/WO2011126332A3/ko
Priority to US13/648,228 priority Critical patent/US20130273595A1/en

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8675—Evaluation, i.e. decoding of the signal into analytical information
    • G01N30/8682—Group type analysis, e.g. of components having structural properties in common
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N2030/062—Preparation extracting sample from raw material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Library & Information Science (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

본 발명은 인삼 시료로부터 대사체를 추출하는 제1단계; 상기 추출된 대사체를 LC/MS 또는 GC/MS를 이용하여 분석하는 제2단계; 상기 LC/MS 또는 GC/MS 분석 결과를 통계처리 가능한 수치로 변환하는 제3단계; 및 상기 변환된 수치를 이용하여 통계학적 방법으로 분석하여 인삼 연근을 판별하는 제4단계를 포함하여 구성되는 크로마토그래피-질량분석을 이용하는 인삼 연근 판별 방법에 관한 것이다. 본 발명은 LC/MS 또는 GC/MS를 이용한 대사체학 분석기법을 이용하여 인삼의 대사체를 분석함으로써 인삼의 연근을 단시간 내에 정확하고 정밀하게 판별할 수 있고, 세근을 이용할 경우 인삼 뿌리의 손실을 최소화할 수 있는 이점이 있다.
PCT/KR2011/002466 2010-04-09 2011-04-07 크로마토그래피 질량분석을 이용한 인삼 연근 판별 방법 WO2011126332A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/648,228 US20130273595A1 (en) 2010-04-09 2012-10-09 Method for determining age of ginseng roots using chromatogramphy-mass spectroscopy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2010-0032980 2010-04-09
KR1020100032980A KR101149236B1 (ko) 2010-04-09 2010-04-09 크로마토그래피?질량분석을 이용한 인삼 연근 판별 방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/648,228 Continuation US20130273595A1 (en) 2010-04-09 2012-10-09 Method for determining age of ginseng roots using chromatogramphy-mass spectroscopy

Publications (2)

Publication Number Publication Date
WO2011126332A2 WO2011126332A2 (ko) 2011-10-13
WO2011126332A3 true WO2011126332A3 (ko) 2012-03-15

Family

ID=44763429

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/002466 WO2011126332A2 (ko) 2010-04-09 2011-04-07 크로마토그래피 질량분석을 이용한 인삼 연근 판별 방법

Country Status (3)

Country Link
US (1) US20130273595A1 (ko)
KR (1) KR101149236B1 (ko)
WO (1) WO2011126332A2 (ko)

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KR101928802B1 (ko) * 2012-08-09 2018-12-17 (주)아모레퍼시픽 인삼의 재배조건 구분용 바이오마커의 선정방법
KR101402607B1 (ko) * 2012-08-27 2014-06-03 주식회사 유니베라 여러 크기의 알로에 베라의 질량 분광법 기반 대사체 프로파일링 및 그 바이오마커
CN103776911A (zh) * 2012-10-22 2014-05-07 中国科学院大连化学物理研究所 一种用于微量组织中代谢物组和脂质组同时提取分析的方法
KR101444579B1 (ko) * 2013-02-01 2014-09-30 중앙대학교 산학협력단 인삼 연근 판별용 바이오마커 조성물
CN103675131A (zh) * 2013-12-05 2014-03-26 柳州联海科技有限公司 气相色谱-质谱检测细胞内糖的方法
CN103675132B (zh) * 2013-12-05 2016-05-11 张绪伟 气相色谱-质谱检测细胞内中氨基酸、糖、有机酸的方法
CN104820043B (zh) * 2015-05-25 2017-03-08 江苏耐雀生物工程技术有限公司 一种茶树精油的gc色谱分析方法
US10825567B1 (en) * 2015-08-21 2020-11-03 Food2Life, LLC Apparatus and method for informed personal well-being decision making
CN105588908B (zh) * 2015-12-09 2017-07-28 中山市中广测协同创新中心 基于指纹图谱的微损鉴别刺猬紫檀种属的方法
KR102552779B1 (ko) 2016-08-17 2023-07-10 (주)아모레퍼시픽 유기산을 이용한 유기농 인삼의 판별 방법
KR101965293B1 (ko) * 2016-08-29 2019-04-03 서울대학교산학협력단 한국산과 중국산 백미 판별용 Biomarker 및 이를 이용한 판별 모델
CN109212121A (zh) * 2018-09-10 2019-01-15 华润三九（雅安）药业有限公司 红参药材指纹图谱及其与制剂成分关联性的构建方法
KR102430947B1 (ko) 2020-11-11 2022-08-09 대한민국 근적외선분광분석기를 이용한 인삼 및 가공인삼의 연근 판별방법
CN112684029B (zh) * 2020-12-05 2022-11-04 云南省烟草农业科学研究院 一种基于烟叶差异代谢物含量快速检测烟叶成熟度的方法及装置

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Also Published As

Publication number Publication date
KR101149236B1 (ko) 2012-05-25
US20130273595A1 (en) 2013-10-17
WO2011126332A2 (ko) 2011-10-13
KR20110113531A (ko) 2011-10-17

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