WO2010114100A1 - 二剤性医薬用容器 - Google Patents
二剤性医薬用容器 Download PDFInfo
- Publication number
- WO2010114100A1 WO2010114100A1 PCT/JP2010/056028 JP2010056028W WO2010114100A1 WO 2010114100 A1 WO2010114100 A1 WO 2010114100A1 JP 2010056028 W JP2010056028 W JP 2010056028W WO 2010114100 A1 WO2010114100 A1 WO 2010114100A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nozzle cap
- cap
- ratchet teeth
- container
- container body
- Prior art date
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D41/00—Caps, e.g. crown caps or crown seals, i.e. members having parts arranged for engagement with the external periphery of a neck or wall defining a pouring opening or discharge aperture; Protective cap-like covers for closure members, e.g. decorative covers of metal foil or paper
- B65D41/32—Caps or cap-like covers with lines of weakness, tearing-strips, tags, or like opening or removal devices, e.g. to facilitate formation of pouring openings
- B65D41/34—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D41/00—Caps, e.g. crown caps or crown seals, i.e. members having parts arranged for engagement with the external periphery of a neck or wall defining a pouring opening or discharge aperture; Protective cap-like covers for closure members, e.g. decorative covers of metal foil or paper
- B65D41/32—Caps or cap-like covers with lines of weakness, tearing-strips, tags, or like opening or removal devices, e.g. to facilitate formation of pouring openings
- B65D41/34—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt
- B65D41/3404—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt with ratchet-and-pawl mechanism between the container and the closure skirt or the tamper element
- B65D41/3409—Threaded or like caps or cap-like covers provided with tamper elements formed in, or attached to, the closure skirt with ratchet-and-pawl mechanism between the container and the closure skirt or the tamper element the tamper element being integrally connected to the closure by means of bridges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
- A61J1/1418—Threaded type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D35/00—Pliable tubular containers adapted to be permanently or temporarily deformed to expel contents, e.g. collapsible tubes for toothpaste or other plastic or semi-liquid material; Holders therefor
- B65D35/44—Closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D47/00—Closures with filling and discharging, or with discharging, devices
- B65D47/04—Closures with discharging devices other than pumps
- B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D47/00—Closures with filling and discharging, or with discharging, devices
- B65D47/04—Closures with discharging devices other than pumps
- B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
- B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
Definitions
- a nozzle cap is provided on the container body, for example. It is known that a drug extraction port is provided on the head of the nozzle cap and the head is screwed with a cap.
- the nozzle cap is rotated in the opening direction to remove the nozzle cap from the container body.
- the second component is added, and then the nozzle cap is rotated in the closing direction to close the container body, and then the cap is rotated in the opening direction to remove the cap from the nozzle cap. At the same time, it may rotate in the opening direction, and the medicine may be spilled from the mouth of the loose container body.
- the present invention has been made in view of the above circumstances, and its main purpose is that a nozzle cap is screwed onto a container body, a chemical liquid extraction port is provided on the head of the nozzle cap, and the head is screwed with the cap.
- the container body and nozzle cap do not loosen until the two parts are mixed, and can be easily removed by breaking the ratchet part during mixing. After that, this part cannot be easily opened, so that even when the cap is rotated in the opening direction, the nozzle cap and the container main body are kept closed without loosening, and only the cap can be removed.
- the object is to provide a pharmaceutical container.
- FIG. 3 is an exploded perspective view of the two-component pharmaceutical container according to the present invention, with a cap omitted and a nozzle cap partially cut away.
- (A) is the figure which looked at the container main body of FIG. 1 from upper direction.
- (B) is the figure which looked at the container main body of FIG. 1 from the front.
- (A) is a front half sectional view of the nozzle cap of FIG. (B) is the figure which looked at the nozzle cap of (a) from the downward direction.
- (A) is a longitudinal cross-sectional view which shows the state before use of the container of FIG. (B) is the sectional view on the AA line of (a).
- (A) is a longitudinal cross-sectional view which shows the state which closed the container main body with the nozzle cap which fractured
- (B) is a sectional view taken along line BB of (a).
- the sealing ring portion 23 has an outer diameter larger than the outer diameter of the outer cylinder 25, and lower inner ratchet teeth 29 are provided on the inner peripheral surface thereof.
- the sealing ring portion 23 is connected to the barrel portion 22 by being connected to a breakable connecting portion 41 provided along the circumferential direction at the lower end edge of the barrel portion 22 at the upper end edge (see FIG. 3). ).
- the downward projecting piece 42 on the lower end edge of the body portion 22 is plugged in the circumferential direction more than the downward projecting piece 42 on the upper end edge of the sealing ring portion 23.
- an upward projecting piece 43 is provided adjacent to the same circumference, and the front lower end of the downward projecting piece 42 is higher than the rear upper end of the upward projecting piece 43. It extends downward.
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Closures For Containers (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
〔1〕 第一成分が充填され、ノズル部の外周面に雄ねじが設けられた容器本体と、前記雄ねじと螺合する雌ねじが筒体内周面に設けられた胴部と、該胴部の内部と連通する薬液
抽出口を備えた頭部と、該胴部の下端縁に周方向に沿って設けられた破断可能な複数の連結部を介して設けられた封緘用リング部とを有するノズルキャップと、前記ノズルキャップの頭部を覆うように螺着されたキャップとからなり、
前記容器本体のノズル部の下部には、該ノズル部の雄ねじの外径より大きい外径を有する小径環状部と、該小径環状部の下方に、該小径環状部の外径より大きい外径を有する大径環状部とが設けられるとともに、該小径環状部の外周面には上段外ラチェット歯が、該大径環状部の外周面には下段外ラチェット歯がそれぞれ設けられてなる一方、前記ノズルキャップの構成部材のうち、胴部の下部内周面には上段内ラチェット歯が、前記封緘用リング部の内周面には下段内ラチェット歯がそれぞれ設けられており、
前記ノズルキャップの胴部の雌ねじを前記容器本体の雄ねじに螺合させて容器本体を閉栓する位置まで回動した閉栓状態では、前記上段内ラチェット歯と前記上段外ラチェット歯は係合しないが、前記下段内ラチェット歯と前記下段外ラチェット歯が係合して開栓方向への回動を阻止するように構成されており、
さらに、前記ノズルキャップの連結部を破断して、前記封緘用リング部を取り外したノズルキャップの胴部の雌ねじを前記容器本体の雄ねじに螺合させて容器本体を閉栓する位置まで回動した閉栓状態では、前記上段内ラチェット歯と前記上段外ラチェット歯が係合して開栓方向への回動を阻止するように構成されている二剤性医薬用容器、
〔2〕 ノズルキャップの構成部材のうち、胴部の下端縁に下向き突片が、封緘用リング部の上端縁で前記下向き突片よりも周方向閉栓側に上向き突片が近接して設けられており、前記下向き突片の前部下端が前記上向き突片の後部上端よりも下方に延出されている、前記〔1〕記載の二剤性医薬用容器、
〔3〕 点眼用、点耳用および点鼻用のいずれかに用いられる前記〔1〕または〔2〕記載の二剤性医薬用容器。
〔4〕 前記〔1〕~〔3〕のいずれか記載の二剤性医薬用容器を使用するにあたり、ノズルキャップを開栓方向に回動操作して連結部を破断し、容器本体から封緘用リング部を有さないノズルキャップと封緘用リング部とを取り外し、次いで容器本体に第二成分を添加して前記ノズルキャップを閉栓方向に回動操作して容器本体を閉栓し、続いてキャップを開栓方向に回動操作してノズルキャップからキャップを取り外し、薬液抽出口から第一成分と第二成分を含有する薬液を吐出させるようにする、二剤性医薬用容器の使用方法。
ノズルキャップ2の胴部22の雌ねじ27を容器本体1の雄ねじ13に螺合させて閉栓方向に回動操作してノズルキャップ2を容器本体1に螺着させる工程を含む。上記工程では、封緘用リング部23が図5(a)に示す所定の位置まで回動して下段内ラチェット歯29と下段外ラチェット歯17が係合した時に回動操作が終了するが、さらに回動操作を続けると胴部22が回動し過ぎて連結部41が破断するおそれがある。そこで、本発明では、下向き突片42の前端が上向き突片43の後端に当接することで胴部22の過度の回動を規制し、適切な回動操作が行われるようにしている。
2 ノズルキャップ
3 キャップ
12 ノズル部
13 雄ねじ
14 小径環状部
15 大径環状部
16 上段外ラチェット歯
17 下段外ラチェット歯
21 頭部
21b 薬液抽出口
22 胴部
23 封緘用リング部
25 外筒
27 雌ねじ
28 上段内ラチェット歯
29 下段内ラチェット歯
41 連結部
42 下向き突片
43 上向き突片
Claims (4)
- 第一成分が充填され、ノズル部の外周面に雄ねじが設けられた容器本体と、前記雄ねじと螺合する雌ねじが筒体内周面に設けられた胴部と、該胴部の内部と連通する薬液抽出口を備えた頭部と、該胴部の下端縁に周方向に沿って設けられた破断可能な複数の連結部を介して設けられた封緘用リング部とを有するノズルキャップと、前記ノズルキャップの頭部を覆うように螺着されたキャップとからなり、
前記容器本体のノズル部の下部には、該ノズル部の雄ねじの外径より大きい外径を有する小径環状部と、該小径環状部の下方に、該小径環状部の外径より大きい外径を有する大径環状部とが設けられるとともに、該小径環状部の外周面には上段外ラチェット歯が、該大径環状部の外周面には下段外ラチェット歯がそれぞれ設けられてなる一方、前記ノズルキャップの構成部材のうち、胴部の下部内周面には上段内ラチェット歯が、前記封緘用リング部の内周面には下段内ラチェット歯がそれぞれ設けられており、
前記ノズルキャップの胴部の雌ねじを前記容器本体の雄ねじに螺合させて容器本体を閉栓する位置まで回動した閉栓状態では、前記上段内ラチェット歯と前記上段外ラチェット歯は係合しないが、前記下段内ラチェット歯と前記下段外ラチェット歯が係合して開栓方向への回動を阻止するように構成されており、
さらに、前記ノズルキャップの連結部を破断して容器本体から封緘用リング部を取り外し、前記封緘用リング部を有さないノズルキャップの胴部の雌ねじを前記容器本体の雄ねじに螺合させて容器本体を閉栓する位置まで回動した閉栓状態では、前記上段内ラチェット歯と前記上段外ラチェット歯が係合して開栓方向への回動を阻止するように構成されている二剤性医薬用容器。 - ノズルキャップの構成部材のうち、胴部の下端縁に下向き突片が、封緘用リング部の上端縁で前記下向き突片よりも周方向閉栓側に上向き突片が近接して設けられており、前記下向き突片の前部下端が前記上向き突片の後部上端よりも下方に延出されている、請求項1記載の二剤性医薬用容器。
- 点眼用、点耳用および点鼻用のいずれかに用いられる請求項1または2記載の二剤性医薬用容器。
- 請求項1~3のいずれか記載の二剤性医薬用容器を使用するにあたり、ノズルキャップを開栓方向に回動操作して連結部を破断し、容器本体から封緘用リング部を有さないノズルキャップと封緘用リング部とを取り外し、次いで容器本体に第二成分を添加して前記ノズルキャップを閉栓方向に回動操作して容器本体を閉栓し、続いてキャップを開栓方向に回動操作してノズルキャップからキャップを取り外し、薬液抽出口から第一成分と第二成分を含有する薬液を吐出させるようにする、二剤性医薬用容器の使用方法。
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010800152381A CN102378723A (zh) | 2009-04-02 | 2010-04-01 | 双成分药剂用容器 |
CA2757299A CA2757299A1 (en) | 2009-04-02 | 2010-04-01 | Two-drug pharmaceutical container |
US13/260,579 US20120018318A1 (en) | 2009-04-02 | 2010-04-01 | Two-drug pharmaceutical container |
JP2011507293A JPWO2010114100A1 (ja) | 2009-04-02 | 2010-04-01 | 二剤性医薬用容器 |
EP10758871A EP2415686A4 (en) | 2009-04-02 | 2010-04-01 | CONTAINER FOR A MEDICAMENT COMPRISING TWO COMPONENTS |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009090182 | 2009-04-02 | ||
JP2009-090182 | 2009-04-02 |
Publications (1)
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WO2010114100A1 true WO2010114100A1 (ja) | 2010-10-07 |
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ID=42828389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/JP2010/056028 WO2010114100A1 (ja) | 2009-04-02 | 2010-04-01 | 二剤性医薬用容器 |
Country Status (8)
Country | Link |
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US (1) | US20120018318A1 (ja) |
EP (1) | EP2415686A4 (ja) |
JP (1) | JPWO2010114100A1 (ja) |
KR (1) | KR20120008021A (ja) |
CN (1) | CN102378723A (ja) |
CA (1) | CA2757299A1 (ja) |
TW (1) | TW201102057A (ja) |
WO (1) | WO2010114100A1 (ja) |
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JP2014108280A (ja) * | 2012-12-03 | 2014-06-12 | Asahi Kasei Medical Co Ltd | 医療用容器 |
EP4385916A1 (de) * | 2022-12-14 | 2024-06-19 | Neutec Chemie GmbH | Produktaufnahmebehälter mit gewindeadapter |
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KR101598995B1 (ko) | 2014-07-10 | 2016-03-03 | 강릉원주대학교산학협력단 | 와이어 위치 감지장치 |
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US10759554B2 (en) * | 2017-02-02 | 2020-09-01 | Rai Strategic Holdings, Inc. | Dispenser unit for aerosol precursor |
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2010
- 2010-04-01 KR KR20117019639A patent/KR20120008021A/ko not_active Application Discontinuation
- 2010-04-01 CA CA2757299A patent/CA2757299A1/en not_active Abandoned
- 2010-04-01 US US13/260,579 patent/US20120018318A1/en not_active Abandoned
- 2010-04-01 JP JP2011507293A patent/JPWO2010114100A1/ja not_active Withdrawn
- 2010-04-01 CN CN2010800152381A patent/CN102378723A/zh active Pending
- 2010-04-01 TW TW99110165A patent/TW201102057A/zh unknown
- 2010-04-01 WO PCT/JP2010/056028 patent/WO2010114100A1/ja active Application Filing
- 2010-04-01 EP EP10758871A patent/EP2415686A4/en not_active Withdrawn
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JPH07330000A (ja) * | 1994-06-06 | 1995-12-19 | Toyo Seikan Kaisha Ltd | 容器キャップの戻り回転防止機構 |
JP2002154563A (ja) * | 2000-11-17 | 2002-05-28 | Dainippon Printing Co Ltd | キャップと注出口の組合体 |
JP2003292009A (ja) * | 2002-03-29 | 2003-10-15 | Hanshin Kasei Kogyo Kk | 容器の蓋構造 |
JP2004018019A (ja) * | 2002-06-14 | 2004-01-22 | Taisei Kako Co Ltd | 用時混合容器セット |
Non-Patent Citations (1)
Title |
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See also references of EP2415686A4 |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2700425A1 (en) * | 2011-04-20 | 2014-02-26 | Taisei Kako Co., Ltd. | Barrel with attached cap, prefilled syringe, and cap with attached connector |
JPWO2012144026A1 (ja) * | 2011-04-20 | 2014-07-28 | 大成化工株式会社 | キャップ付きバレル、プレフィルドシリンジ、及びコネクタ付きキャップ |
EP2700425A4 (en) * | 2011-04-20 | 2014-12-17 | Taisei Kako Co | SPRAYING PISTON WITH FIXED CAP, FINISHED SYRINGE AND CAP WITH A FIXED CONNECTOR |
JP5782506B2 (ja) * | 2011-04-20 | 2015-09-24 | 大成化工株式会社 | キャップ付きバレル、プレフィルドシリンジ、及びコネクタ付きキャップ |
US9604012B2 (en) | 2011-04-20 | 2017-03-28 | Taisei Kako Co., Ltd. | Barrel with cap, pre-filled syringe, and cap with connector |
JP2013071781A (ja) * | 2011-09-29 | 2013-04-22 | Toppan Printing Co Ltd | 二重キャップ付き口栓およびパウチ |
JP2013209142A (ja) * | 2012-03-30 | 2013-10-10 | Yoshino Kogyosho Co Ltd | 混合容器用キャップ |
JP2014108280A (ja) * | 2012-12-03 | 2014-06-12 | Asahi Kasei Medical Co Ltd | 医療用容器 |
EP4385916A1 (de) * | 2022-12-14 | 2024-06-19 | Neutec Chemie GmbH | Produktaufnahmebehälter mit gewindeadapter |
Also Published As
Publication number | Publication date |
---|---|
US20120018318A1 (en) | 2012-01-26 |
EP2415686A1 (en) | 2012-02-08 |
CA2757299A1 (en) | 2010-10-07 |
EP2415686A4 (en) | 2012-08-15 |
KR20120008021A (ko) | 2012-01-25 |
CN102378723A (zh) | 2012-03-14 |
JPWO2010114100A1 (ja) | 2012-10-11 |
TW201102057A (en) | 2011-01-16 |
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