WO2010098629A3 - 메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법 - Google Patents

메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법 Download PDF

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Publication number
WO2010098629A3
WO2010098629A3 PCT/KR2010/001250 KR2010001250W WO2010098629A3 WO 2010098629 A3 WO2010098629 A3 WO 2010098629A3 KR 2010001250 W KR2010001250 W KR 2010001250W WO 2010098629 A3 WO2010098629 A3 WO 2010098629A3
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WO
WIPO (PCT)
Prior art keywords
methionine
dimethyl sulfide
methyl mercaptan
mixture
increasing
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Application number
PCT/KR2010/001250
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English (en)
French (fr)
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WO2010098629A2 (ko
Inventor
김소영
신용욱
허인경
김현아
김주은
서창일
손성광
이상목
전성후
이한진
나광호
김일출
Original Assignee
씨제이제일제당 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 씨제이제일제당 주식회사 filed Critical 씨제이제일제당 주식회사
Priority to ES10746468.7T priority Critical patent/ES2618407T3/es
Priority to DK10746468.7T priority patent/DK2402453T3/en
Priority to JP2011551987A priority patent/JP5481497B2/ja
Priority to EP10746468.7A priority patent/EP2402453B1/en
Priority to CN201080009632.4A priority patent/CN102333881B/zh
Priority to US13/203,521 priority patent/US9024063B2/en
Publication of WO2010098629A2 publication Critical patent/WO2010098629A2/ko
Publication of WO2010098629A3 publication Critical patent/WO2010098629A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

본 발명은 L-메치오닌 및 유기산 생산 효율을 증진시키는 방법에 관한 것이다. 더욱 상세하게는 메치오닌 전구체인 O-아세틸 호모세린 또는 O-숙시닐 호모세린, 및 메치오닌 전환 활성을 가진 효소에 적정한 비율로 혼합된 메칠머캅탄과 디메칠설파이드의 혼합물을 첨가하여 효소 반응을 수행함으로써 L-메치오닌 전구체로부터 L-메치오닌 및 유기산의 전환율을 향상시켜 종래 방법에 비하여 높은 수율로 L-메치오닌을 생산할 수 있는 방법에 관한 것이다.
PCT/KR2010/001250 2009-02-27 2010-02-26 메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법 WO2010098629A2 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ES10746468.7T ES2618407T3 (es) 2009-02-27 2010-02-26 Procedimiento para aumentar la productividad de metionina usando una mezcla de metil mercaptano y sulfuro de dimetilo
DK10746468.7T DK2402453T3 (en) 2009-02-27 2010-02-26 Process for Increasing Methionine Productivity Using a Mixture of Methylmercaptan and Dimethyl Sulfide
JP2011551987A JP5481497B2 (ja) 2009-02-27 2010-02-26 メチルメルカプタンとジメチルスルフィドの混合物を使用してメチオニン生産能を増加させる方法
EP10746468.7A EP2402453B1 (en) 2009-02-27 2010-02-26 Method for increasing methionine productivity using a mixture of methyl mercaptan and dimethyl sulfide
CN201080009632.4A CN102333881B (zh) 2009-02-27 2010-02-26 使用甲硫醇和二甲硫醚的混合物增加蛋氨酸产率的方法
US13/203,521 US9024063B2 (en) 2009-02-27 2010-02-26 Method for increasing methionine productivity using a mixture of methyl mercaptan and dimethyl sulfide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0016604 2009-02-27
KR1020090016604A KR101048593B1 (ko) 2009-02-27 2009-02-27 메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법

Publications (2)

Publication Number Publication Date
WO2010098629A2 WO2010098629A2 (ko) 2010-09-02
WO2010098629A3 true WO2010098629A3 (ko) 2010-12-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/001250 WO2010098629A2 (ko) 2009-02-27 2010-02-26 메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법

Country Status (10)

Country Link
US (1) US9024063B2 (ko)
EP (1) EP2402453B1 (ko)
JP (1) JP5481497B2 (ko)
KR (1) KR101048593B1 (ko)
CN (1) CN102333881B (ko)
DK (1) DK2402453T3 (ko)
ES (1) ES2618407T3 (ko)
MY (1) MY152999A (ko)
PL (1) PL2402453T3 (ko)
WO (1) WO2010098629A2 (ko)

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KR101250651B1 (ko) 2010-12-21 2013-04-03 씨제이제일제당 (주) 신규 ｏ-아세틸호모세린 설피드릴라제 또는 변이체 및 이를 이용한 메치오닌 전환 방법
RU2598276C2 (ru) * 2010-12-29 2016-09-20 СиДжей ЧеилДжеданг Корпорейшн Способ получения l-метионина и родственных продуктов
EP2751276B1 (en) * 2011-09-02 2023-01-25 Arkema France Preparation process of l-methionine
FR3041658B1 (fr) * 2015-09-30 2017-10-20 Arkema France Procede de production de l-methionine
KR101836719B1 (ko) 2015-10-13 2018-04-20 씨제이제일제당 (주) O-아세틸호모세린 설피드릴라제 변이체 및 이를 이용한 l-메치오닌 제조 방법
RU2729012C2 (ru) * 2015-11-27 2020-08-03 Эвоник Оперейшенс ГмбХ Способ получения l-метионина
CN111315877B (zh) 2017-06-30 2023-08-08 Cj第一制糖株式会社 新型o-琥珀酰高丝氨酸转移酶变体及使用其生产o-琥珀酰高丝氨酸的方法
US10982245B2 (en) 2017-06-30 2021-04-20 Cj Cheiljedang Corporation O-succinyl homoserine transferase mutant and method for producing O-succinyl homoserine using same
CN108250114B (zh) * 2018-03-01 2023-12-29 贵州兴发化工有限公司 一种甲硫醇钠生产工艺及装置
KR102221040B1 (ko) 2019-05-09 2021-03-03 씨제이제일제당 주식회사 L-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산을 생산하는 방법
KR102182497B1 (ko) 2019-12-20 2020-11-24 씨제이제일제당 주식회사 내막 단백질의 변이체 및 이를 이용한 목적 산물 생산 방법
AU2022250692B2 (en) 2021-04-01 2024-01-04 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate and its phosphoesters
CN113088503B (zh) * 2021-04-27 2023-01-10 浙江工业大学 一种o-琥珀酰巯基转移酶突变体及其在l-甲硫氨酸合成中的应用
CN113215124A (zh) * 2021-04-27 2021-08-06 浙江工业大学 一种o-琥珀酰巯基转移酶在l-甲硫氨酸合成中的应用
WO2024061456A1 (en) 2022-09-21 2024-03-28 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate and its phosphoesters
WO2024061455A1 (en) * 2022-09-21 2024-03-28 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate and its phosphoesters
CN118581171A (zh) * 2023-03-01 2024-09-03 湖南利尔生物科技有限公司 一种从l-高丝氨酸直接制备l-甲硫氨酸的方法

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KR20080033413A (ko) * 2005-07-18 2008-04-16 바스프 에스이 미생물 내에서 메티오닌 생산을 위한 디메틸 디술파이드의용도

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BRPI0614891A2 (pt) * 2005-08-18 2012-12-25 Basf Se mÉtodo, dispositivo e elemento de programa para determinar um organismo com eficiÊncia aumentada para a sÍntese de metionina, meio legÍvel por computador, mÉtodo para produzir um organismo, organismo, mÉtodos para produzir um microorganismo do gÊnero corynebacterium e do gÊnero escherichia com eficiÊncia aumentada da produÇço de metionina, microorganismos dos gÊneros corynebacterium e escherichia, uso de qualquer um dos organismos, e, mÉtodo para produzir metionina
SI2426144T1 (sl) 2007-02-23 2019-02-28 Merck Sharp & Dohme Corp. Umetno proizvedena anti-IL23P19 antitelesa

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KR20080033413A (ko) * 2005-07-18 2008-04-16 바스프 에스이 미생물 내에서 메티오닌 생산을 위한 디메틸 디술파이드의용도
KR20080011132A (ko) * 2006-07-28 2008-01-31 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
KR20080102123A (ko) * 2006-07-28 2008-11-24 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌 전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법

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Also Published As

Publication number Publication date
US9024063B2 (en) 2015-05-05
EP2402453A2 (en) 2012-01-04
PL2402453T3 (pl) 2017-09-29
DK2402453T3 (en) 2017-03-13
CN102333881A (zh) 2012-01-25
ES2618407T3 (es) 2017-06-21
US20120123158A1 (en) 2012-05-17
EP2402453B1 (en) 2016-12-14
KR101048593B1 (ko) 2011-07-12
JP5481497B2 (ja) 2014-04-23
KR20100097782A (ko) 2010-09-06
EP2402453A4 (en) 2013-11-20
MY152999A (en) 2014-12-31
JP2012518432A (ja) 2012-08-16
WO2010098629A2 (ko) 2010-09-02
CN102333881B (zh) 2014-03-12

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