WO2009075346A1 - 走査型レーザ顕微鏡 - Google Patents
走査型レーザ顕微鏡 Download PDFInfo
- Publication number
- WO2009075346A1 WO2009075346A1 PCT/JP2008/072611 JP2008072611W WO2009075346A1 WO 2009075346 A1 WO2009075346 A1 WO 2009075346A1 JP 2008072611 W JP2008072611 W JP 2008072611W WO 2009075346 A1 WO2009075346 A1 WO 2009075346A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- scanning
- line
- time required
- laser microscope
- microscope
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/008—Details of detection or image processing, including general computer control
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
- G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
- G02B26/10—Scanning systems
- G02B26/105—Scanning systems with one or more pivoting mirrors or galvano-mirrors
Landscapes
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Multimedia (AREA)
- General Engineering & Computer Science (AREA)
- Microscoopes, Condenser (AREA)
Abstract
本発明は、任意のフレームレートで画像を取得することができる走査型レーザ顕微鏡に関する。 コントローラ61は、設定されたフレームレートから求められる1フレームの走査に必要な時間に基づいて、1ラインの走査に用いられる時間として要求される要求ライン走査時間を算出し、レーザ光を1ラインずつスキャンさせる走査手段を駆動する駆動波形データの1ライン分のデータ数、および、駆動波形データの読み出し周期のうちの少なくともいずれか一方を調整して、スキャナ14Xがレーザ光を1ライン走査する時間を、要求ライン走査時間に略一致させる。本発明は、例えば、共焦点レーザ走査型顕微鏡に適用できる。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08858605A EP2237097A4 (en) | 2007-12-13 | 2008-12-12 | SCANNING LASER MICROSCOPE |
JP2009545455A JP5083325B2 (ja) | 2007-12-13 | 2008-12-12 | 走査型レーザ顕微鏡 |
US12/814,166 US8194311B2 (en) | 2007-12-13 | 2010-06-11 | Scanning laser microscope |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007322064 | 2007-12-13 | ||
JP2007-322064 | 2007-12-13 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/814,166 Continuation US8194311B2 (en) | 2007-12-13 | 2010-06-11 | Scanning laser microscope |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009075346A1 true WO2009075346A1 (ja) | 2009-06-18 |
Family
ID=40755582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/072611 WO2009075346A1 (ja) | 2007-12-13 | 2008-12-12 | 走査型レーザ顕微鏡 |
Country Status (4)
Country | Link |
---|---|
US (1) | US8194311B2 (ja) |
EP (1) | EP2237097A4 (ja) |
JP (1) | JP5083325B2 (ja) |
WO (1) | WO2009075346A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011112780A (ja) * | 2009-11-25 | 2011-06-09 | Olympus Corp | 走査型顕微鏡 |
WO2012002893A1 (en) * | 2010-06-30 | 2012-01-05 | Ge Healthcare Bio-Sciences Corp | A system for synchronization in a line scanning imaging microscope |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103698880B (zh) * | 2013-12-26 | 2016-01-27 | 中国科学院苏州生物医学工程技术研究所 | 激光扫描共聚焦显微镜用二维针孔电动实时调整系统 |
US20180267284A1 (en) * | 2015-01-31 | 2018-09-20 | Board Of Regents, The University Of Texas System | High-speed laser scanning microscopy platform for high-throughput automated 3d imaging and functional volumetric imaging |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003098468A (ja) | 2001-09-20 | 2003-04-03 | Nikon Corp | スキャナ装置およびそれを備えたコンフォーカル顕微鏡 |
JP2003177323A (ja) * | 2001-12-11 | 2003-06-27 | Olympus Optical Co Ltd | 走査型レーザ顕微鏡、駆動波形データ生成方法、及びその制御プログラム |
JP2005352030A (ja) * | 2004-06-09 | 2005-12-22 | Olympus Corp | 走査型レーザ観察装置、観察方法及び観察プログラム |
JP2006145857A (ja) * | 2004-11-19 | 2006-06-08 | Olympus Corp | 走査型レーザ顕微鏡 |
JP2006195440A (ja) * | 2004-12-13 | 2006-07-27 | Olympus Corp | 走査型レーザ顕微鏡装置 |
JP2006227600A (ja) * | 2005-01-18 | 2006-08-31 | Olympus Corp | 走査型顕微鏡および標本画像取得方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7852551B2 (en) * | 2004-06-14 | 2010-12-14 | Olympus Corporation | Optical-scanning microscope examination apparatus |
DE102004034951A1 (de) * | 2004-07-16 | 2006-02-02 | Carl Zeiss Jena Gmbh | Verfahren zur bildlichen Erfassung von Objekten mittels eines Lichtrastermikrokopes mit linienförmiger Abtastung |
JP2006119347A (ja) * | 2004-10-21 | 2006-05-11 | Olympus Corp | レーザ走査型顕微鏡 |
US7696996B2 (en) * | 2004-12-13 | 2010-04-13 | Olympus Corporation | Laser scanning microscope apparatus |
US7612350B2 (en) | 2005-01-18 | 2009-11-03 | Olympus Corporation | Scanning microscope and specimen image obtaining method in which adjacent data obtaining points are not consecutively obtained |
-
2008
- 2008-12-12 WO PCT/JP2008/072611 patent/WO2009075346A1/ja active Application Filing
- 2008-12-12 JP JP2009545455A patent/JP5083325B2/ja active Active
- 2008-12-12 EP EP08858605A patent/EP2237097A4/en not_active Withdrawn
-
2010
- 2010-06-11 US US12/814,166 patent/US8194311B2/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003098468A (ja) | 2001-09-20 | 2003-04-03 | Nikon Corp | スキャナ装置およびそれを備えたコンフォーカル顕微鏡 |
JP2003177323A (ja) * | 2001-12-11 | 2003-06-27 | Olympus Optical Co Ltd | 走査型レーザ顕微鏡、駆動波形データ生成方法、及びその制御プログラム |
JP2005352030A (ja) * | 2004-06-09 | 2005-12-22 | Olympus Corp | 走査型レーザ観察装置、観察方法及び観察プログラム |
JP2006145857A (ja) * | 2004-11-19 | 2006-06-08 | Olympus Corp | 走査型レーザ顕微鏡 |
JP2006195440A (ja) * | 2004-12-13 | 2006-07-27 | Olympus Corp | 走査型レーザ顕微鏡装置 |
JP2006227600A (ja) * | 2005-01-18 | 2006-08-31 | Olympus Corp | 走査型顕微鏡および標本画像取得方法 |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011112780A (ja) * | 2009-11-25 | 2011-06-09 | Olympus Corp | 走査型顕微鏡 |
WO2012002893A1 (en) * | 2010-06-30 | 2012-01-05 | Ge Healthcare Bio-Sciences Corp | A system for synchronization in a line scanning imaging microscope |
JP2013531819A (ja) * | 2010-06-30 | 2013-08-08 | ジーイー・ヘルスケア・バイオサイエンス・コーポレイション | ライン走査式顕微鏡における同期用システム |
US10027855B2 (en) | 2010-06-30 | 2018-07-17 | Ge Healthcare Bio-Science Corp. | System for synchronization in a line scanning imaging microscope |
Also Published As
Publication number | Publication date |
---|---|
JPWO2009075346A1 (ja) | 2011-04-28 |
EP2237097A4 (en) | 2013-02-27 |
JP5083325B2 (ja) | 2012-11-28 |
US8194311B2 (en) | 2012-06-05 |
EP2237097A1 (en) | 2010-10-06 |
US20100245994A1 (en) | 2010-09-30 |
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