WO2009065119A2 - Edible energy composition with low caffeine - Google Patents

Edible energy composition with low caffeine Download PDF

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Publication number
WO2009065119A2
WO2009065119A2 PCT/US2008/083778 US2008083778W WO2009065119A2 WO 2009065119 A2 WO2009065119 A2 WO 2009065119A2 US 2008083778 W US2008083778 W US 2008083778W WO 2009065119 A2 WO2009065119 A2 WO 2009065119A2
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WO
WIPO (PCT)
Prior art keywords
amount
present
energy composition
refinement
energy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/083778
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English (en)
French (fr)
Other versions
WO2009065119A3 (en
Inventor
Manoj Bhargava
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIO CLINICAL DEVELOPMENT Inc
BIO CLINICAL Dev Inc
Original Assignee
BIO CLINICAL DEVELOPMENT Inc
BIO CLINICAL Dev Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2008322414A priority Critical patent/AU2008322414C1/en
Priority to EP08850385.9A priority patent/EP2214521B1/en
Priority to CN200880116265.0A priority patent/CN101873807B/zh
Priority to JP2010534260A priority patent/JP2011502539A/ja
Priority to RU2010119181/13A priority patent/RU2487645C2/ru
Priority to BRPI0819070-4A priority patent/BRPI0819070B1/pt
Priority to US12/742,778 priority patent/US8993033B2/en
Priority to MX2010005319A priority patent/MX2010005319A/es
Priority to ES08850385T priority patent/ES2716226T3/es
Application filed by BIO CLINICAL DEVELOPMENT Inc, BIO CLINICAL Dev Inc filed Critical BIO CLINICAL DEVELOPMENT Inc
Priority to CA2704481A priority patent/CA2704481C/en
Publication of WO2009065119A2 publication Critical patent/WO2009065119A2/en
Publication of WO2009065119A3 publication Critical patent/WO2009065119A3/en
Priority to IL205500A priority patent/IL205500A/en
Priority to ZA2010/03325A priority patent/ZA201003325B/en
Anticipated expiration legal-status Critical
Priority to US14/670,935 priority patent/US9526268B2/en
Priority to US15/390,571 priority patent/US9943098B2/en
Priority to US15/954,692 priority patent/US10201179B2/en
Priority to US16/272,280 priority patent/US10721955B2/en
Priority to US16/939,498 priority patent/US11540551B2/en
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/56—Flavouring or bittering agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • the present invention relates to edible compositions with a low caffeine concentration that provide an individual with an energy burst when consumed.
  • Energy drinks are beverages that provide an individual with an energy surge that lasts for a variable period of time. Coffee, which is perhaps the best known energy drink, derives most of its energy enhancing properties from caffeine. Recently, there has been an increase in the number of soft drinks that also provide an energy boost that is equal to or superior to coffee. In addition, such energy drinks may also include sugar which also provides a transient increase in an individual's perceived energy levels.
  • the present invention solves one or more problems of the prior art by providing an edible energy composition.
  • the present invention provides a healthy alternative in energy and focus providing drinks, with one feature being increased availability of wholesome nutrients.
  • a choline source (particularly useful is citicoline) is utilized and is surprisingly effective even with low levels (or even no levels) of caffeine in boosting energy levels in individuals who drink the present formulations.
  • the energy composition of this embodiment includes a methylated xanthine at a relatively low concentration, a choline derivative, and at least one flavorant in a sufficient amount to render the energy composition palatable. Characteristically, the composition of the present embodiment includes low levels fo the methylated xanthine.
  • the stimulating effects of the present embodiment occur within minutes or hours of consumption.
  • the energy composition may also include vitamins, amino acids, enzymes, preservatives, and the like.
  • an edible energy composition comprises caffeine in an amount less than about 0.00045 g/ml; choline in an amount from about 0.0004 mg/ml to about 0.009 mg/ml, amino acids or an amino acid derivative in an amount from about 0.01 to about 0.03 mg/ml, vitamins in an amount from about 0.0003 to about 0.01 mg/ml, glucuronolactone is present in an amount from about 0.003 to about 0.01 mg/ml, and at least one flavorant in a sufficient amount to render the energy composition palatable.
  • an edible energy composition comprises caffeine in an amount from about 0.00008 g/ml to about 0.0004 g/ml, citicoline in an amount from about 0.0008 g/ml to about 0.007 g/ml, amino acids or an amino acid derivative in an amount from about 0.0125 to about 0.025 mg/ml, vitamins in an amount from about 0.0010 to about 0.005 mg/ml, glucuronolactone is present in an amount from about 0.005 to about 0.009 mg/ml, and at least one flavorant in a sufficient amount to render the energy composition palatable.
  • percent, "parts of, " and ratio values are by weight; the description of a group or class of materials as suitable or preferred for a given purpose in connection with the invention implies that mixtures of any two or more of the members of the group or class are equally suitable or preferred; description of constituents in chemical terms refers to the constituents at the time of addition to any combination specified in the description, and does not necessarily preclude chemical interactions among the constituents of a mixture once mixed; the first definition of an acronym or other abbreviation applies to all subsequent uses herein of the same abbreviation and applies mutatis mutandis to normal grammatical variations of the initially defined abbreviation; and, unless expressly stated to the contrary, measurement of a property is determined by the same technique as previously or later referenced for the same property.
  • an edible energy composition in an embodiment of the present invention, includes water and a combination of at least two stimulants.
  • the energy composition includes a methylated xanthine and a choline derivative.
  • methylated xanthines include but are not limited to caffeine and theobromine. Caffeine is particularly useful in the practice of the present invention.
  • the methylated xanthine is present in an amount from less than about 0.00045 g/ml.
  • the methylated xanthine is present in an amount from less than about 0.0004 g/ml.
  • the methylated xanthine is present in an amount from about 0.00008 g/ml to about 0.0004 g/ml. In still another embodiment of the present embodiment, the methylated xanthine is present in an amount from about 0.0001 g/ml to about 0.0003 g/ml.
  • Variations of the present invention also include a choline.
  • a particularly useful choline is citicoline which is a well-known brain enhancer.
  • Brain enhancers are substances that are known to improve an individual's mental acuity.
  • the choline derivative is present in an amount from about 0.0004 mg/ml to about 0.009 mg/ml. In another refinement, the choline derivative is present in an amount from about 0.0008 g/ml to about 0.007 g/ml. In still another refinement, the choline derivative is present in an amount from about 0.001 g/ml to about 0.005 g/ml.
  • the choline to caffeine ratio can be 10: 1 or even 500: 1 with a preferred range of between 10: 1 to 20: 1 by weight respectively.
  • the present invention can achieve the desired effect of energy and focus by increasing the ratio of choline.
  • the amount of niacin is decreased, or even eliminated, to what is known in the art
  • the energy composition further comprises one or more vitamins.
  • vitamins include, but are not limited to B6, B12, niacinamide, niacin, folic acid, and the like.
  • vitamins are present in an amount from about 0.0003 g/ml to about 0.01 g/ml.
  • vitamins are present in an amount from about 0.0001 g/ml to about 0.005 g/ml.
  • vitamins are present in an amount from about 0.0003 g/ml to about 0.004 g/ml.
  • the energy composition may include vitamin B6.
  • the B6 is present in an amount from about 0.0003 g/ml to about
  • the B6 is present in an amount from about 0.0005 g/ml to about 0.0008 g/ml. In still another refinement, the B6 is present in an amount from about 0.0006 g/ml to about 0.0008 g/ml.
  • the energy composition may include vitamin B 12.
  • the B 12 is present in an amount from about 0.000001 g/ml to about
  • the B 12 is present in an amount from about 0.000007 g/ml to about 0.00001 g/ml. In still another refinement, the B 12 is present in an amount from about 0.000006 g/ml to about 0.00001 g/ml.
  • the energy composition may include niacin or a niacin derivative such as niacinamide.
  • the niacin or a derivative thereof is present in an amount from about 0 g/ml to about 0.003 g/ml.
  • the niacin or a derivative thereof is present in an amount from about 0.0001 g/ml to about 0.0007 g/ml.
  • the niacinamide or a derivative thereof is present in an amount from about 0.00006 g/ml to about 0.0001 g/ml.
  • the energy composition may include folic acid.
  • the folic acid is present in an amount from about 0 g/ml to about 0.0002 g/ml. In a refinement, the folic acid is present in an amount from 0.000005 g/ml to about 0.00008 g/ml. In still another refinement, the folic is present in an amount from about 0.000004 g/ml to about 0.000009 g/ml.
  • the energy composition of the present embodiment includes one or more flavorants and/or sweeteners. Characteristically, there are a sufficient number of flavorants and/or sweeteners so that unpalatable tasting components will be masked. Such masking is particularly necessary for caffeine and choline.
  • the flavorants are present in an amount from about 0 g/ml to about 0.008 g/ml. In another refinement of the present invention, the flavorants are present in an amount from about 0.001 g/ml to about 0.008 g/ml.
  • Sucralose is an example of a sweetener that may be used in the present embodiment. In a refinement, sucralose is present in an amount from about 0 to about 0.004 g/ml.
  • sucralose is present in an amount from about 0.0005 to about 0.004 g/ml. In a refinement, sucralose is present in an amount from about 0.0008 to about 0.003 g/ml. In still another refinement, sucralose is present in an amount from about 0.001 to about 0.002 g/ml. Ethylene diamine tetraacetic acid ("EDTA") may also be included in the present embodiment to improve flavor. In a refinement, EDTA is present in an amount from about 0.00002 g/ml to about 0.00009 g/ml. In another refinement, the EDTA is present in an amount from about 0.00003 g/ml to about 0.00007 g/ml.
  • EDTA Ethylene diamine tetraacetic acid
  • the EDTA is present in an amount from about 0.00004 g/ml to about 0.00006 g/ml. In still another refinement, the EDTA is present in an amount from about 0.00002 g/ml to about 0.00003 g/ml.
  • the energy composition also includes one or more fruit flavorants. Such fruit flavorants include, but are not limited to lemon lime flavors, orange flavors, berry flavors, high fructose corn syrup, raspberry juice concentrates, berry juice concentrates and the like. In another variation of the present embodiment, the energy composition further comprises one or more amino acids or amino acid derivatives.
  • amino acids or derivatives thereof include, but are not limited to, N- acetyl L- tyrosine, L-phenylalanine, taurine, and combinations thereof.
  • amino acids or derivatives thereof are present in an amount from about 0.005 to about 0.05 g/ml.
  • amino acids or derivatives thereof are present in an amount from about 0.01 to about 0.03 g/ml.
  • amino acids or derivatives thereof are present in an amount from about 0.0125 to about 0.025 g/ml.
  • N-acetyl L-tyrosine is present in an amount from about 0.001 to about 0.01 g/ml.
  • N-acetyl L-tyrosine is present in an amount from about 0.002 to about 0.009 g/ml. In still another refinement, N- acetyl L-tyrosine is present in an amount from about 0.003 to about 0.007 g/ml.
  • L-phenylalanine is present in an amount from about 0.001 to about 0.008 g/ml. In a refinement, L-phenylalanine is present in an amount from about 0.002 to about 0.007 g/ml. In still another refinement, L- phenylalanine is present in an amount from about 0.003 to about 0.007 g/ml.
  • taurine is present in an amount from about 0.002 to about 0.016 g/ml. In a refinement, taurine is present in an amount from about 0.005 to about 0.013 g/ml. In still another refinement, taurine is present in an amount from about 0.005 to about 0.012 g/ml.
  • the energy composition of the present invention further includes additional components that reduce fatigue.
  • additional components include, for example glucuronolactone.
  • glucuronolactone is present in an amount from about 0.001 to about 0.012 g/ml.
  • glucuronolactone is present in an amount from about 0.003 to about 0.001 g/ml.
  • glucuronolactone is present in an amount from about 0.005 to about 0.009 g/ml.
  • the energy composition further includes one or more pH -modifying components.
  • the pH-modifying components are acidulants.
  • such pH- modifying components are inorganic acids or edible organic acids such as malic acid and citric acid.
  • the pH-modifying components are present in an amount from about 0.001 to about 0.012 g/ml.
  • the pH-modifying components are present in an amount from about 0.003 to about 0.0009 g/ml.
  • the pH-modifying components are present in an amount from about 0.004 to about 0.007 g/ml.
  • the energy composition includes added fiber.
  • Cellulose is an example of a fiber that may be used in the present variation.
  • the energy composition further includes one or more enzymes.
  • enzymes include, but are not limited to, amylase, protease, lactase, lipase, cellulase, and combinations thereof.
  • the energy composition further comprises a preservative.
  • the preservative is a natural preservative.
  • useful preservatives include, but are not limited to, benzoic acid and benzoic acid derivatives such as sodium benzoate, calcium benzoate, potassium benzoate, magnesium benzoate, and combinations thereof; and sorbic acid derivatives such as potassium sorbate.
  • the preservative is present in an amount from about 0 to about 0.01 g/ml. In a refinement, the preservative is present in an amount from about 0.001 to about 0.008 g/ml. In still another refinement, the preservative is present in an amount from about 0.004 to about 0.006 g/ml.
  • a composition comprising the formulations as set forth in Table 1 is provided. The compositions of Table 1 are formed by blending or mixture the components in any order. Blends or mixtures such as those in Table 1 may be introduced into a suitable liquid such as water to form a drink. Table 1. Edible Energy Compositions
  • compositions of the present invention are made by introducing suitable amounts of the ingredients set forth in Table 1 into a suitable edible liquid.
  • Water is a particularly useful liquid for this purpose. It is to be appreciated that each of the components hereof are water soluble.
  • the ingredients are mixed together at room temperature, in any order, and the solid ingredients, which are in powdered form, are readily solubilized in the water. Those components that have more difficulty are solubilized through the utilization of chelating properties of the EDTA.
  • Tables 2 - 4 provide a set of components that may be introduced into such a liquid. The amounts provided in Tables 2 - 4 are particularly useful to form compositions having a total final volume of about 60 ml.
  • dry ingredients may be mixed together and then added to liquid, each ingredient added to a container of liquid in succession, or the like.
  • the process may be adjusted for solubility, as is known in the art.
  • One such routine technique is to utilize EDTA to enhance solubility. Any temperature in which the ingredients do not lose significant functional or aesthetic qualities is acceptable. Processing at room temperature is preferred. Each of the components are commercially available.
  • the energy drink composition is storage stable for extended periods at room temperature. To the extent that there is any separation or precipitation out of solution, stirring with agitation will re-solubilize the precipitate. Table 2. Edible Energy Composition Amounts in 60 ml water
  • the present invention relates to edible compositions with a low caffeine concentration that provide an individual with an energy burst when consumed.
  • Energy drinks are beverages that provide an individual with an energy surge that lasts for a variable period of time. Coffee, which is perhaps the best known energy drink, derives most of its energy enhancing properties from caffeine. Recently, there has been an increase in the number of soft drinks that also provide an energy boost that is equal to or superior to coffee. In addition, such energy drinks may also include sugar which also provides a transient increase in an individual's perceived energy levels.
  • the present invention solves one or more problems of the prior art by providing an edible energy composition.
  • the present invention provides a healthy alternative in energy and focus providing drinks, with one feature being increased availability of wholesome nutrients.
  • a choline source (particularly useful is citicoline) is utilized and is surprisingly effective even with low levels (or even no levels) of caffeine in boosting energy levels in individuals who drink the present formulations.
  • the energy composition of this embodiment includes a methylated xanthine at a relatively low concentration, a choline derivative, and at least one flavorant in a sufficient amount to render the energy composition palatable. Characteristically, the composition of the present embodiment includes low levels fo the methylated xanthine.
  • the stimulating effects of the present embodiment occur within minutes or hours of consumption.
  • the energy composition may also include vitamins, amino acids, enzymes, preservatives, and the like.
  • an edible energy composition comprises caffeine in an amount less than about 0.00045 g/ml; choline in an amount from about 0.0004 mg/ml to about 0.009 mg/ml, amino acids or an amino acid derivative in an amount from about 0.01 to about 0.03 mg/ml, vitamins in an amount from about 0.0003 to about 0.01 mg/ml, glucuronolactone is present in an amount from about 0.003 to about 0.01 mg/ml, and at least one flavorant in a sufficient amount to render the energy composition palatable.
  • an edible energy composition comprises caffeine in an amount from about 0.00008 g/ml to about 0.0004 g/ml, citicoline in an amount from about 0.0008 g/ml to about 0.007 g/ml, amino acids or an amino acid derivative in an amount from about 0.0125 to about 0.025 mg/ml, vitamins in an amount from about 0.0010 to about 0.005 mg/ml, glucuronolactone is present in an amount from about 0.005 to about 0.009 mg/ml, and at least one flavorant in a sufficient amount to render the energy composition palatable.
  • percent, "parts of, " and ratio values are by weight; the description of a group or class of materials as suitable or preferred for a given purpose in connection with the invention implies that mixtures of any two or more of the members of the group or class are equally suitable or preferred; description of constituents in chemical terms refers to the constituents at the time of addition to any combination specified in the description, and does not necessarily preclude chemical interactions among the constituents of a mixture once mixed; the first definition of an acronym or other abbreviation applies to all subsequent uses herein of the same abbreviation and applies mutatis mutandis to normal grammatical variations of the initially defined abbreviation; and, unless expressly stated to the contrary, measurement of a property is determined by the same technique as previously or later referenced for the same property.
  • an edible energy composition in an embodiment of the present invention, includes water and a combination of at least two stimulants.
  • the energy composition includes a methylated xanthine and a choline derivative.
  • methylated xanthines include but are not limited to caffeine and theobromine. Caffeine is particularly useful in the practice of the present invention.
  • the methylated xanthine is present in an amount from less than about 0.00045 g/ml.
  • the methylated xanthine is present in an amount from less than about 0.0004 g/ml.
  • the methylated xanthine is present in an amount from about 0.00008 g/ml to about 0.0004 g/ml. In still another embodiment of the present embodiment, the methylated xanthine is present in an amount from about 0.0001 g/ml to about 0.0003 g/ml.
  • Variations of the present invention also include a choline (e.g. , choline bitartrate).
  • a choline e.g. , choline bitartrate
  • a particularly useful choline is citicoline which is a well-known brain enhancer. Brain enhancers are substances that are known to improve an individual's mental acuity.
  • the choline derivative is present in an amount from about 0.0004 mg/ml to about 0.009 mg/ml.
  • the choline derivative is present in an amount from about 0.0004 mg/ml to about 0.009 mg/ml.
  • -4- choline derivative is present in an amount from about 0.0008 g/ml to about 0.007 g/ml.
  • the choline derivative is present in an amount from about 0.001 g/ml to about 0.005 g/ml.
  • the choline to caffeine ratio can be 10: 1 or even 500: 1 with a preferred range of between 10: 1 to 20: 1 by weight respectively.
  • the present invention can achieve the desired effect of energy and focus by increasing the ratio of choline.
  • the amount of niacin is decreased, or even eliminated, to what is known in the art
  • the energy composition further comprises one or more vitamins.
  • vitamins include, but are not limited to B6, B 12, niacinamide, niacin, folic acid, and the like.
  • vitamins are present in an amount from about 0.0003 g/ml to about 0.01 g/ml.
  • vitamins are present in an amount from about 0.0001 g/ml to about 0.005 g/ml.
  • vitamins are present in an amount from about 0.0003 g/ml to about 0.004 g/ml.
  • the energy composition may include vitamin B6.
  • the B6 is present in an amount from about 0.0003 g/ml to about
  • the B6 is present in an amount from about 0.0005 g/ml to about 0.0008 g/ml. In still another refinement, the B6 is present in an amount from about 0.0006 g/ml to about 0.0008 g/ml.
  • the energy composition may include vitamin B 12.
  • the B12 is present in an amount from about 0.000001 g/ml to about
  • the B12 is present in an amount from about 0.000007 g/ml to about 0.00001 g/ml. In still another refinement, the B 12 is present in an amount from about 0.000006 g/ml to about 0.00001 g/ml.
  • the energy composition may include niacin or a niacin derivative such as niacinamide.
  • the niacin or a derivative thereof is present in an amount from about 0 g/ml to about 0.003 g/ml.
  • the niacin or a derivative thereof is present in an amount from about 0.0001 g/ml to about 0.0007 g/ml.
  • the niacinamide or a derivative thereof is present in an amount from about 0.00006 g/ml to about 0.0001 g/ml.
  • the energy composition may include folic acid.
  • the folic acid is present in an amount from about 0 g/ml to about 0.0002 g/ml. In a refinement, the folic acid is present in an amount from 0.000005 g/ml to about 0.00008 g/ml. In still another refinement, the folic is present in an amount from about 0.000004 g/ml to about 0.000009 g/ml.
  • the energy composition of the present embodiment includes one or more flavorants and/or sweeteners. Characteristically, there are a sufficient number of flavorants and/or sweeteners so that unpalatable tasting components will be masked. Such masking is particularly necessary for caffeine and choline.
  • the flavorants are present in an amount from about 0 g/ml to about 0.008 g/ml. In another refinement of the present invention, the flavorants are present in an amount from about 0.001 g/ml to about 0.008 g/ml.
  • Sucralose is an example of a sweetener that may be used in the present embodiment. In a refinement, sucralose is present in an amount from about 0 to about 0.004 g/ml. In a refinement, sucralose is present in an amount from about 0.0005 to about 0.004 g/ml. In a refinement, sucralose is present in an amount from about 0.0008 to about 0.003 g/ml.
  • sucralose is present in an amount from about 0.001 to about 0.002 g/ml.
  • Ethylene diamine tetraacetic acid (“EDTA”) may also be included in the present embodiment to improve flavor.
  • EDTA is present in an amount from about 0.00002 g/ml to about 0.00009 g/ml.
  • the EDTA is present in an amount from about 0.00003 g/ml to about 0.00007 g/ml.
  • the EDTA is present in an amount from about 0.00004 g/ml to about 0.00006 g/ml.
  • the EDTA is present in an amount from about 0.00002 g/ml to about 0.00003 g/ml.
  • the energy composition also includes one or more fruit flavorants.
  • fruit flavorants include, but are not limited to lemon lime flavors, orange flavors, berry flavors, high fructose corn syrup, raspberry juice concentrates, berry juice concentrates and the like.
  • the energy composition further comprises one or more amino acids or amino acid derivatives.
  • amino acids or derivatives thereof include, but are not limited to, N- acetyl L-tyrosine, L-phenylalanine, taurine, and combinations thereof.
  • amino acids or derivatives thereof are present in an amount from about 0.005 to about 0.05 g/ml.
  • amino acids or derivatives thereof are present in an amount from about 0.01 to about 0.03 g/ml.
  • amino acids or derivatives thereof are present in an amount from about 0.0125 to about 0.025 g/ml.
  • N-acetyl L-tyrosine is present in an amount from about 0.001 to about 0.01 g/ml. In a refinement, N-acetyl L-tyrosine is present in an amount from about 0.002 to about 0.009 g/ml. In still another refinement, N- acetyl L-tyrosine is present in an amount from about 0.003 to about 0.007 g/ml.
  • L-phenylalanine is present in an amount from about 0.001 to about 0.008 g/ml. In a refinement, L-phenylalanine is present in an amount from about 0.002 to about 0.007 g/ml. In still another refinement, L- phenylalanine is present in an amount from about 0.003 to about 0.007 g/ml.
  • taurine is present in an amount from about 0.002 to about 0.016 g/ml. In a refinement, taurine is present in an amount from about 0.005 to about 0.013 g/ml. In still another refinement, taurine is present in an amount from about 0.005 to about 0.012 g/ml.
  • the energy composition of the present invention further includes additional components that reduce fatigue.
  • additional components include, for example glucuronolactone.
  • glucuronolactone is present in an amount from about 0.001 to about 0.012 g/ml.
  • glucuronolactone is present in an amount from about 0.003 to about 0.001 g/ml.
  • glucuronolactone is present in an amount from about 0.005 to about 0.009 g/ml.
  • the energy composition further includes one or more pH-modifying components.
  • the pH-modifying components are acidulants. Typically, such pH- modifying components are inorganic acids or edible organic acids such as malic acid and citric acid. In a refinement, the pH-modifying components are present in an amount from about 0.001 to about 0.012 g/ml. In a refinement, the pH-modifying components are present in an amount from about 0.003 to about 0.0009 g/ml. In still another refinement, the pH-modifying components are present in an amount from about 0.004 to about 0.007 g/ml.
  • the energy composition includes added fiber.
  • Cellulose is an example of a fiber that may be used in the present variation.
  • the energy composition further includes one or more enzymes.
  • enzymes include, but are not limited to, amylase, protease, lactase, lipase, cellulase, and combinations thereof.
  • the energy composition further comprises a preservative.
  • the preservative is a natural preservative.
  • useful preservatives include, but are not limited to, benzoic acid and benzoic acid derivatives such as sodium benzoate, calcium benzoate, potassium benzoate, magnesium benzoate, and combinations thereof; and sorbic acid derivatives such as potassium sorbate.
  • the preservative is present in an amount from about 0 to about 0.01 g/ml. In a refinement, the preservative is present in an amount from about 0.001 to about 0.008 g/ml. In still another refinement, the preservative is present in an amount from about 0.004 to about 0.006 g/ml.
  • compositions comprising the formulations as set forth in Table 1 is provided.
  • the compositions of Table 1 are formed by blending or mixture the components in any order. Blends or mixtures such as those in Table 1 may be introduced into a suitable liquid such as water to form a drink.
  • compositions of the present invention are made by introducing suitable amounts of the ingredients set
  • Table 1 -9- forth in Table 1 into a suitable edible liquid.
  • Water is a particularly useful liquid for this purpose. It is to be appreciated that each of the components hereof are water soluble. Thus, in preparing the beverage, the ingredients are mixed together at room temperature, in any order, and the solid ingredients, which are in powdered form, are readily solubilized in the water. Those components that have more difficulty are solubilized through the utilization of chelating properties of the EDTA.
  • Tables 2 - 4 provide a set of components that may be introduced into such a liquid. The amounts provided in Tables 2 - 4 are particularly useful to form compositions having a total final volume of about 60 ml.
  • dry ingredients may be mixed together and then added to liquid, each ingredient added to a container of liquid in succession, or the like.
  • the process may be adjusted for solubility, as is known in the art.
  • One such routine technique is to utilize EDTA to enhance solubility. Any temperature in which the ingredients do not lose significant functional or aesthetic qualities is acceptable. Processing at room temperature is preferred.
  • Each of the components are commercially available.
  • the energy drink composition is storage stable for extended periods at room temperature. To the extent that there is any separation or precipitation out of solution, stirring with agitation will re-solubilize the precipitate.

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  • Life Sciences & Earth Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
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  • Mycology (AREA)
  • Pediatric Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
PCT/US2008/083778 2007-11-16 2008-11-17 Edible energy composition with low caffeine Ceased WO2009065119A2 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
ES08850385T ES2716226T3 (es) 2007-11-16 2008-11-17 Composición energética comestible con un contenido bajo en cafeína
EP08850385.9A EP2214521B1 (en) 2007-11-16 2008-11-17 Edible energy composition with low caffeine
CN200880116265.0A CN101873807B (zh) 2007-11-16 2008-11-17 含低咖啡因的可食能量组合物
JP2010534260A JP2011502539A (ja) 2007-11-16 2008-11-17 低カフェイン可食性活力組成物
RU2010119181/13A RU2487645C2 (ru) 2007-11-16 2008-11-17 Пищевая энергетическая композиция с низким содержанием кофеина
BRPI0819070-4A BRPI0819070B1 (pt) 2007-11-16 2008-11-17 Composição energética comestível
US12/742,778 US8993033B2 (en) 2007-11-16 2008-11-17 Edible energy composition with low caffeine
MX2010005319A MX2010005319A (es) 2007-11-16 2008-11-17 Composicion energetica comestible con bajo contenido de cafeina.
CA2704481A CA2704481C (en) 2007-11-16 2008-11-17 Edible energy composition with low caffeine, comprising choline
AU2008322414A AU2008322414C1 (en) 2007-11-16 2008-11-17 Edible energy composition with low caffeine
IL205500A IL205500A (en) 2007-11-16 2010-05-02 An edible energy compound containing caffeine, choline derivative and at least one flavoring
ZA2010/03325A ZA201003325B (en) 2007-11-16 2010-05-11 Edible energy composition with low caffeine
US14/670,935 US9526268B2 (en) 2007-11-16 2015-03-27 Edible energy composition with low caffeine
US15/390,571 US9943098B2 (en) 2007-11-16 2016-12-26 Edible energy composition with low caffeine
US15/954,692 US10201179B2 (en) 2007-11-16 2018-04-17 Edible energy composition with low caffeine
US16/272,280 US10721955B2 (en) 2007-11-16 2019-02-11 Edible energy composition with low caffeine
US16/939,498 US11540551B2 (en) 2007-11-16 2020-07-27 Edible edible composition with low caffeine

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AU (1) AU2008322414C1 (enExample)
BR (1) BRPI0819070B1 (enExample)
CA (1) CA2704481C (enExample)
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IL (1) IL205500A (enExample)
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US20100285179A1 (en) 2010-11-11
CA2704481C (en) 2015-12-22
PT2214521T (pt) 2019-03-29
RU2010119181A (ru) 2011-12-27
US9943098B2 (en) 2018-04-17
US20150196047A1 (en) 2015-07-16
US9526268B2 (en) 2016-12-27
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US11540551B2 (en) 2023-01-03
JP2011502539A (ja) 2011-01-27
US10201179B2 (en) 2019-02-12
WO2009065119A3 (en) 2009-07-09
IL205500A0 (en) 2010-12-30
AU2008322414B2 (en) 2013-11-28
MX2010005319A (es) 2010-06-02
BRPI0819070A2 (pt) 2014-10-07
BRPI0819070B1 (pt) 2023-12-12
US20200352207A1 (en) 2020-11-12
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EP2214521A2 (en) 2010-08-11
RU2487645C2 (ru) 2013-07-20
US20200196652A9 (en) 2020-06-25
US8993033B2 (en) 2015-03-31
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US20180228199A1 (en) 2018-08-16
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