WO2009049274A8 - Micro-organisme modifié pour produire de l'isopropanol - Google Patents

Micro-organisme modifié pour produire de l'isopropanol Download PDF

Info

Publication number
WO2009049274A8
WO2009049274A8 PCT/US2008/079667 US2008079667W WO2009049274A8 WO 2009049274 A8 WO2009049274 A8 WO 2009049274A8 US 2008079667 W US2008079667 W US 2008079667W WO 2009049274 A8 WO2009049274 A8 WO 2009049274A8
Authority
WO
WIPO (PCT)
Prior art keywords
produce isopropanol
microorganism engineered
engineered
microorganism
isopropanol
Prior art date
Application number
PCT/US2008/079667
Other languages
English (en)
Other versions
WO2009049274A2 (fr
WO2009049274A3 (fr
Inventor
James C. Liao
Shota Atsumi
Taizo Hanai
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Priority to AU2008310573A priority Critical patent/AU2008310573A1/en
Priority to BRPI0817545-4A2A priority patent/BRPI0817545A2/pt
Priority to CA2702361A priority patent/CA2702361A1/fr
Priority to EP08838137A priority patent/EP2198039A4/fr
Priority to CN2008801190646A priority patent/CN101903530A/zh
Priority to US12/682,554 priority patent/US20100221800A1/en
Priority to JP2010529132A priority patent/JP2011500031A/ja
Publication of WO2009049274A2 publication Critical patent/WO2009049274A2/fr
Publication of WO2009049274A3 publication Critical patent/WO2009049274A3/fr
Publication of WO2009049274A8 publication Critical patent/WO2009049274A8/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des micro-organismes métaboliquement modifiés pour produire des biocarburants.
PCT/US2008/079667 2007-10-12 2008-10-11 Micro-organisme modifié pour produire de l'isopropanol WO2009049274A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU2008310573A AU2008310573A1 (en) 2007-10-12 2008-10-11 Microorganism engineered to produce isopropanol
BRPI0817545-4A2A BRPI0817545A2 (pt) 2007-10-12 2008-10-11 Microorganismo recombinante, métodos para produzir um microorganismo recombinante e para produzir isopropanol, vetor recombinante, e, célula hospedeira recombinante.
CA2702361A CA2702361A1 (fr) 2007-10-12 2008-10-11 Micro-organisme modifie pour produire de l'isopropanol
EP08838137A EP2198039A4 (fr) 2007-10-12 2008-10-11 Micro-organisme modifié pour produire de l'isopropanol
CN2008801190646A CN101903530A (zh) 2007-10-12 2008-10-11 被改造以产生异丙醇的微生物
US12/682,554 US20100221800A1 (en) 2007-10-12 2008-10-11 Microorganism engineered to produce isopropanol
JP2010529132A JP2011500031A (ja) 2007-10-12 2008-10-11 イソプロパノールを生産するように操作された微生物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97973107P 2007-10-12 2007-10-12
US80/979,731 2007-10-12
US60/979,731 2007-10-12

Publications (3)

Publication Number Publication Date
WO2009049274A2 WO2009049274A2 (fr) 2009-04-16
WO2009049274A3 WO2009049274A3 (fr) 2009-05-28
WO2009049274A8 true WO2009049274A8 (fr) 2010-05-27

Family

ID=40550578

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/079667 WO2009049274A2 (fr) 2007-10-12 2008-10-11 Micro-organisme modifié pour produire de l'isopropanol

Country Status (9)

Country Link
US (1) US20100221800A1 (fr)
EP (1) EP2198039A4 (fr)
JP (1) JP2011500031A (fr)
KR (1) KR20100087695A (fr)
CN (1) CN101903530A (fr)
AU (1) AU2008310573A1 (fr)
BR (1) BRPI0817545A2 (fr)
CA (1) CA2702361A1 (fr)
WO (1) WO2009049274A2 (fr)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
WO2008115840A2 (fr) 2007-03-16 2008-09-25 Genomatica, Inc. Compositions et procédés pour la biosynthèse de 1,4-butanediol et de ses précurseurs
US9074226B2 (en) * 2007-07-11 2015-07-07 Mitsui Chemicals, Inc. Isopropyl alcohol-producing bacterium and method of producing isopropyl alcohol using the same
EP2188243A2 (fr) 2007-08-10 2010-05-26 Genomatica, Inc. Procedes de synthese d'acide acrylique et de ces derives a partir d'acide fumarique
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
JP2011509691A (ja) 2008-01-22 2011-03-31 ジェノマティカ, インコーポレイテッド 合成ガスまたは他のガス状炭素源およびメタノールを利用するための方法および生物体
US10093552B2 (en) 2008-02-22 2018-10-09 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
US9259662B2 (en) 2008-02-22 2016-02-16 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
US8986963B2 (en) * 2008-02-23 2015-03-24 James Weifu Lee Designer calvin-cycle-channeled production of butanol and related higher alcohols
AU2009217293B2 (en) 2008-02-23 2014-11-20 James Weifu Lee Designer organisms for photobiological butanol production from carbon dioxide and water
EP2262901B1 (fr) 2008-03-05 2018-11-21 Genomatica, Inc. Organismes de production d alcools primaires
SI2265709T1 (en) 2008-03-27 2018-03-30 Genomatica, Inc. MICROORGANISMS FOR PREPARATION OF ADYPIC ACID AND OTHER COMPOUNDS
BRPI0911759A2 (pt) 2008-05-01 2019-09-24 Genomatica Inc microorganismo para a produção de ácido metacrílico
CA2725549A1 (fr) 2008-06-17 2009-12-23 Genomatica, Inc. Micro-organismes et procedes pour la biosynthese de fumarate, malate, et acrylate
AU2009291825B2 (en) 2008-09-10 2016-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
US20100184173A1 (en) * 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
WO2010071697A1 (fr) 2008-12-16 2010-06-24 Genomatica, Inc. Micro-organismes et procédés pour la conversion de gaz de synthèse et d'autres sources de carbone en produits utiles
DE102009002583A1 (de) * 2009-04-23 2010-10-28 Evonik Degussa Gmbh Zellen und Verfahren zur Herstellung von Aceton
EP2425006A4 (fr) * 2009-04-30 2013-01-23 Genomatica Inc Organismes pour la production d'isopropanol, de n-butanol et d'isobutanol
EP3318626B1 (fr) 2009-04-30 2020-01-15 Genomatica, Inc. Organismes pour la production d'un 1,3-butanediol
KR102099295B1 (ko) 2009-05-07 2020-04-09 게노마티카 인코포레이티드 아디페이트, 헥사메틸렌디아민 및 6-아미노카프로산의 생합성을 위한 미생물 및 방법
BRPI1012877A2 (pt) 2009-05-15 2016-04-05 Genomatica Inc organismo para produção de ciclohexanona
MY195387A (en) 2009-06-04 2023-01-18 Genomatica Inc Microorganisms for the Production of 1,4-Butanediol and Related Methods
KR102237801B1 (ko) 2009-06-04 2021-04-07 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
US8420375B2 (en) 2009-06-10 2013-04-16 Genomatica, Inc. Microorganisms and methods for carbon-efficient biosynthesis of MEK and 2-butanol
EP3190174A1 (fr) 2009-08-05 2017-07-12 Genomatica, Inc. Acide téréphtalique semi-synthétique par l'intermédiaire de micro-organismes produisant de l'acide muconique
WO2011017288A1 (fr) 2009-08-05 2011-02-10 Chromocell Corporation Plantes, microbes et organismes enrichis
KR20120068021A (ko) * 2009-09-09 2012-06-26 게노마티카 인코포레이티드 아이소프로판올과 1차 알콜, 다이올 및 산과의 공동 생산을 위한 미생물 및 방법
KR20120083908A (ko) 2009-10-13 2012-07-26 게노마티카 인코포레이티드 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-coa, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법
US20110097767A1 (en) 2009-10-23 2011-04-28 Priti Pharkya Microorganisms for the production of aniline
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US8268607B2 (en) 2009-12-10 2012-09-18 Genomatica, Inc. Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
WO2011094131A1 (fr) 2010-01-29 2011-08-04 Genomatica, Inc. Micro-organismes et procédés pour la biosynthèse de p-toluate et téréphtalate
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
JP5628288B2 (ja) * 2010-03-09 2014-11-19 三井化学株式会社 生産性の高いイソプロピルアルコール生産細菌
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
KR20190006103A (ko) 2010-05-05 2019-01-16 게노마티카 인코포레이티드 부타디엔을 생합성하기 위한 미생물 및 방법
US9217183B2 (en) 2010-05-14 2015-12-22 Toyota Jidosha Kabushiki Kaisha Method for producing isopropanol and recombinant yeast capable of producing isopropanol
CN102892892B (zh) * 2010-05-14 2017-10-17 丰田自动车株式会社 异丙醇的制造方法和具有异丙醇生产能力的重组酵母
CN103025877A (zh) 2010-07-26 2013-04-03 基因组股份公司 用于生物合成芳族化合物、2,4-戊二烯酸和1,3-丁二烯的微生物和方法
SG187768A1 (en) 2010-08-12 2013-03-28 Mitsui Chemicals Inc Isopropyl alcohol-producing bacterium having improved productivity by gntr destruction
CN103282376A (zh) 2010-10-29 2013-09-04 诺维信公司 具有琥珀酰CoA:乙酰乙酸转移酶活性的多肽及其编码多核苷酸
WO2012058603A1 (fr) 2010-10-29 2012-05-03 Novozymes A/S Production de n-propanol et d'isopropanol recombinants
JP2013544516A (ja) 2010-11-03 2013-12-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア タンパク質性バイオマスの発酵を介した組換え微生物によるバイオ燃料および化学物質の生成
KR102121886B1 (ko) * 2011-02-25 2020-06-15 란자테크 뉴질랜드 리미티드 재조합 미생물 및 이의 용도
CN102796692B (zh) * 2011-05-25 2014-12-17 中国科学院上海生命科学研究院 一种提高丙酮丁醇梭菌在混合糖发酵中糖利用率的方法
CN102808002B (zh) * 2011-05-31 2015-09-16 中国科学院青岛生物能源与过程研究所 一种生物法合成甲基乙偶姻及其衍生物的重组细胞和方法
WO2013178699A1 (fr) 2012-05-31 2013-12-05 Novozymes A/S Production d'isopropanol par des hôtes bactériens
BR112014030202A2 (pt) 2012-06-04 2017-09-12 Genomatica Inc microorganismos e métodos para a produção de 4-hidroxibutirato 1,4-butanodiol e compostos relacionados
WO2014068010A1 (fr) 2012-10-31 2014-05-08 Novozymes A/S Production d'isopropanol par des hôtes bactériens
WO2014071286A1 (fr) 2012-11-05 2014-05-08 Genomatica, Inc. Micro-organismes pour améliorer la disponibilité d'équivalents de réduction en présence de méthanol et pour la production de 1,2-propanediol
EP2917343A2 (fr) * 2012-11-09 2015-09-16 Lallemand Hungary Liquidity Management LLC Procédé pour la consommation d'acétate pendant la fermentation éthanolique de charges d'alimentation cellulosiques
WO2014076232A2 (fr) 2012-11-19 2014-05-22 Novozymes A/S Production d'isopropanol par des hôtes recombinants à l'aide d'un intermédiaire d'hmg-coa
WO2014089412A1 (fr) 2012-12-07 2014-06-12 Evernu Technology Llc Conversion catalytique d'alcools aliphatiques issus de la biomasse en alcènes ou composés oxygénés de valeur
GB201602576D0 (en) * 2016-02-12 2016-03-30 Bergen Teknologioverforing As Process
CN110382685A (zh) 2016-12-21 2019-10-25 创新生物科学公司 用于提高木糖吸收的表达梅奇酵母木糖转运蛋白的生物和方法
EP3775178A4 (fr) 2018-04-06 2022-01-05 Braskem S.A. Nouveaux mutants d'enzyme dépendant du nadh pour convertir l'acétone en isopropanol
FR3090691B1 (fr) * 2018-12-20 2023-06-09 Ifp Energies Now Bacteries clostridium genetiquement modifiees, preparation et utilisations de celles-ci
CN111087148A (zh) * 2019-12-12 2020-05-01 福建农林大学 一种抑制厌氧产甲烷混菌产甲烷的方法
CN113122475B (zh) * 2021-04-21 2022-07-22 中国科学院上海高等研究院 一种糖多胞菌及其在制备ε-聚赖氨酸中的用途

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4424275A (en) * 1979-09-17 1984-01-03 Sidney Levy Continuous process for producing N-butanol employing anaerobic fermentation
US4568643A (en) * 1981-08-03 1986-02-04 Sidney Levy Continuous process for producing n-butanol employing anaerobic fermentation
US5210032A (en) * 1992-01-21 1993-05-11 Trustees Of The Boston University Degeneration-resistant solventogenic clostridia
EP0883683A1 (fr) * 1996-02-27 1998-12-16 Michigan State University Clonage et expression du gene codant la dehydrogenase d'alcool secondaire thermoanaerobacter ethanolicus 39e et caracterisation biochimique d'enzymes
AU7384098A (en) * 1997-05-14 1998-12-08 Board Of Trustees Of The University Of Illinois, The A method of producing butanol using a mutant strain of (clostridium beijerinckii)
EP1149918A1 (fr) * 2000-04-27 2001-10-31 Creavis Gesellschaft für Technologie und Innovation mbH Procédé d'oxydation d'hydrocarbures en utilisant des microorganismes
CN1491282A (zh) * 2000-12-28 2004-04-21 丰田自动车株式会社 异戊二烯醇的制备方法
AU2003234790A1 (en) * 2002-05-10 2003-11-11 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
AU2003253949A1 (en) * 2002-07-15 2004-02-02 Kosan Biosciences, Inc. Metabolic pathways for starter units in polyketide biosynthesis
GB0218019D0 (en) * 2002-08-05 2002-09-11 Ciba Spec Chem Water Treat Ltd Production of a fermentation product
US20040152159A1 (en) * 2002-11-06 2004-08-05 Causey Thomas B. Materials and methods for the efficient production of acetate and other products
FR2864967B1 (fr) * 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
DE102004029112B4 (de) * 2004-06-11 2007-06-21 Julich Chiral Solutions Gmbh Alkoholdehydrogenase zur stereoselektiven Gewinnung von Hydroxyverbindungen
JP2006204255A (ja) * 2005-01-31 2006-08-10 Canon Inc アセチル−CoAアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法
US9297028B2 (en) * 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
NZ593809A (en) * 2005-10-26 2013-01-25 Butamax Tm Advanced Biofuels Fermentive production of four carbon alcohols
EP2118266A4 (fr) * 2007-02-09 2010-05-19 Univ California Production de biocarburant par des micro-organismes recombinants
EP2134849B1 (fr) * 2007-04-18 2013-07-10 Butamax (TM) Advanced Biofuels LLC Production fermentative d'isobutanol utilisant des enzymes cétol-acide réductoisomérase hautement actives
WO2008131286A1 (fr) * 2007-04-18 2008-10-30 Gevo, Inc. Micro-organismes fabriqués pour produire de l'alcool d'isopropyle
JP5243748B2 (ja) * 2007-08-08 2013-07-24 公益財団法人地球環境産業技術研究機構 ブタノール生産能を有する形質転換体
JP5252940B2 (ja) * 2008-02-08 2013-07-31 公益財団法人地球環境産業技術研究機構 コリネ型細菌形質転換体及びそれを用いるブタノールの製造方法
WO2009120806A2 (fr) * 2008-03-25 2009-10-01 Cobalt Technologies, Inc. Expression d’oxydoréductases pour augmenter la productivité volumétrique
JP2009247217A (ja) * 2008-04-01 2009-10-29 Kyushu Univ 好気性組み換え微生物を用いる2−プロパノールの製造方法

Also Published As

Publication number Publication date
JP2011500031A (ja) 2011-01-06
EP2198039A4 (fr) 2012-05-09
EP2198039A2 (fr) 2010-06-23
CA2702361A1 (fr) 2009-04-16
WO2009049274A2 (fr) 2009-04-16
US20100221800A1 (en) 2010-09-02
KR20100087695A (ko) 2010-08-05
AU2008310573A1 (en) 2009-04-16
BRPI0817545A2 (pt) 2014-11-25
WO2009049274A3 (fr) 2009-05-28
CN101903530A (zh) 2010-12-01

Similar Documents

Publication Publication Date Title
WO2009049274A8 (fr) Micro-organisme modifié pour produire de l'isopropanol
EP2358864B8 (fr) Micro-organismes photosynthétiques modifiés pour la production de triglycérides
EP2147111A4 (fr) Micro-organismes fabriqués pour produire de l'alcool d'isopropyle
MX301000B (es) Produccion de etanol en microorganismos.
WO2008073406A3 (fr) Micro-organismes tolérant les solvants
MY157111A (en) Recombinant microorganisms and methods of production thereof
WO2009002772A3 (fr) Bioréacteur
WO2010014632A3 (fr) Procédés et compositions permettant d'améliorer la production de certains produits dans des micro-organismes
GB0906322D0 (en) Immobilized product tolerant microorganisms
EP2118266A4 (fr) Production de biocarburant par des micro-organismes recombinants
WO2011061032A3 (fr) Cellules, acides nucléiques, enzymes et leur utilisation, ainsi que procédé de production de sophorolipides
TR201903336T4 (tr) Fermantasyonda gelişmiş karbon yakalama.
NZ602201A (en) A novel ethanologenic clostridium species, clostridium coskatii
WO2011006126A3 (fr) Micro-organismes modifiés ayant une activité de fermentation améliorée
WO2009059253A3 (fr) Procédés de production économique de biocarburant à partir de biomasse
WO2010014631A3 (fr) Procédés et compositions permettant d'améliorer la production de certains produits dans des micro-organismes
BRPI0910122A2 (pt) "método de produção de biomassa de levedura"
WO2010045629A3 (fr) Production d'alcool en c5-c8 en utilisant des enzymes évoluées et des micro-organismes à métabolisme modifié
ZA201103570B (en) Microorganism for producing succinic acid
WO2010093182A3 (fr) Microorganisme permettant de produire des l-acides aminés et procédé de production de l-acides aminés l'utilisant
SG10201701701RA (en) Fermentation product containing equol-producing microorganism having maintained equol-producing ability, and method for producing same
WO2009134964A3 (fr) Procédé de fermentation amélioré utilisant des mélasses
WO2009081012A3 (fr) Procedes de production d'acide succinique
EP2319912B8 (fr) Chambre de bioréacteur
WO2009076948A3 (fr) Réductones utilisées pour la production de biogaz

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880119064.6

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08838137

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2010529132

Country of ref document: JP

Ref document number: 12682554

Country of ref document: US

ENP Entry into the national phase

Ref document number: 20107007889

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2702361

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008310573

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 3148/DELNP/2010

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2008838137

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2008310573

Country of ref document: AU

Date of ref document: 20081011

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: PI0817545

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20100409