WO2009048589A1 - Apparatus for supplying surgical staple line reinforcement - Google Patents

Apparatus for supplying surgical staple line reinforcement Download PDF

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Publication number
WO2009048589A1
WO2009048589A1 PCT/US2008/011610 US2008011610W WO2009048589A1 WO 2009048589 A1 WO2009048589 A1 WO 2009048589A1 US 2008011610 W US2008011610 W US 2008011610W WO 2009048589 A1 WO2009048589 A1 WO 2009048589A1
Authority
WO
WIPO (PCT)
Prior art keywords
buttress material
stapler
surgical
pivotable
arms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/011610
Other languages
English (en)
French (fr)
Inventor
Sherif Eskaros
Joseph J. Dipietro, Jr.
Mary Jo Russell
Michael Winterling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gore Enterprise Holdings Inc
Original Assignee
Gore Enterprise Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gore Enterprise Holdings Inc filed Critical Gore Enterprise Holdings Inc
Priority to JP2010528883A priority Critical patent/JP5426558B2/ja
Priority to AU2008311321A priority patent/AU2008311321B2/en
Priority to HK10111396.5A priority patent/HK1144767B/en
Priority to EP08836898.0A priority patent/EP2205164B1/en
Priority to ES08836898T priority patent/ES2426767T3/es
Priority to CA2702033A priority patent/CA2702033C/en
Publication of WO2009048589A1 publication Critical patent/WO2009048589A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
    • A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
    • A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
    • A61B17/07292—Reinforcements for staple line, e.g. pledgets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Definitions

  • the present invention relates to an apparatus for supply of surgical staple line reinforcement material to a surgical stapler.
  • Surgical stapling devices are employed by surgeons to sequentially or simultaneously apply one or more rows of surgical fasteners such as staples or two-part fasteners to body tissue for the purpose of joining segments of body tissue together.
  • Such stapling devices generally consist of a pair of jaws (one being the cartridge side and one being the anvil side) or arm-like structures between which body tissue to be joined is placed.
  • longitudinally moving firing bars contact staple drive members in one of the jaws, thereby pushing surgical staples through body tissue and into an anvil in the opposite jaw which crimps the staples closed.
  • a knife blade can be provided to cut between lines of staples. Examples of such instruments are described in U.S. Patents 4,354,628, 5,014,899 and 5,040,715, teachings of each of which are incorporated herein by reference.
  • Surgical stapling devices have found widespread application in surgical operations where body tissue must be joined or removed, such as, bariatric, colorectal, and thoracic procedures.
  • body tissue When operating on thin tissue, such as thin emphysematous lung tissue, it is important to effectively seal the tissue which can be particularly prone to air leakage. Preventing or reducing air leakage can significantly decrease post operative recovery time. Inhibiting or preventing tearing at the stapled incision site in musculoaponeurotic areas also significantly decreases recovery time.
  • U.S. Patents 5,503,638, 5,575,803, 5,549,628, 5,702,409, 5,810,855 and 5,908,427 describe surgical staple line reinforcement devices and surgical stapling apparatus with tissue bolstering materials.
  • U.S. Patent 5,752,965 and U.S. Patent 6,939,358 describe apparatus for applying surgical reinforcement material onto the working surface of a surgical stapler without requiring removal of excess material.
  • the present invention provides a long felt need for an apparatus that quickly and easily applies a thin and flexible surgical reinforcement material to a stapler.
  • the present invention is an improved apparatus for quickly and easily applying a thin and flexible surgical reinforcement material to a surgical stapler.
  • the present apparatus comprises a body having a surgical reinforcement material attached to a portion of said body, the portion of the said body having the reinforcement material thereon being pivotable with respect to the remainder of said body.
  • a touch-up pad may be attached to the apparatus, or otherwise provided as part of a kit.
  • the apparatus further comprises a securement for temporarily fixing a surgical reinforcement material to the apparatus.
  • the body of the apparatus may be configured so that orientation of the apparatus body with respect to a surgical stapler is able to be reversed with respect to the first side and the second side of the apparatus body.
  • the surgical reinforcement material may further comprise an adhesive on the outermost surface of the surgical reinforcement material with respect to said body.
  • the adhesive may be any suitable adhesive including but not limited to a pressure sensitive adhesive.
  • Figure 1 is a drawing of an embodiment of an apparatus of the present invention.
  • Figure 2 is a drawing of an embodiment of an apparatus of the present invention with a hinged body.
  • Figure 3A is a drawing of an embodiment of a reversible apparatus of the present invention exhibiting securements in the form of posts.
  • Figure 3B is a drawing of an embodiment of an apparatus of the present invention exhibiting securements in the form of posts and an optional touch-up pad.
  • Figure 4 is a drawing of an embodiment of an apparatus of the present invention showing an optional touch-up pad attached to the body via a connecting means.
  • Figures 5A through 5D are drawings showing different embodiments of touch up pads useful in the present invention. .
  • Figure 6 A through 6E are illustrations of the apparatus of the present invention with the pivoting portion of the apparatus shown bending out of the plane of the card.
  • the present invention provides an apparatus for supplying surgical reinforcement material to a surgical stapler.
  • the apparatus 1 of the present invention comprises a body 2 sized to provide a surgical stapler with surgical reinforcement material (Figure 1), on at least a portion of the open stapler arms of the surgical stapler.
  • Figure 1 shows a schematic of the apparatus comprising a body having a first side (illustrated in this Figure as oriented on the top of the apparatus) and a second side.
  • the body 2 of the apparatus also has a first portion and a second portion.
  • the first portion 4 of the body is pivotable with respect to the second portion of the body.
  • a surgical reinforcement material hereinafter referred to as "buttress material” is further disposed over an area of the first portion 4 of said body.
  • the buttress material 3 is secured to the second portion of the body.
  • the body is be sized appropriately to receive a surgical stapler in a manner that permits application of the buttress material 3 onto the jaws of the stapler.
  • the body has a first side 40 and a second side 50 that may be interchangeable for ease of loading a surgical stapler with buttress material. While Figure 1 illustrates the pivotable first portion 4 of the body 2 as being located in a relative central position with respect to the remainder of the body 2, it is understood that the pivotable portion 4 may be located in other desired positions.
  • the pivotable first portion 4 of the body functions to break the buttress material 3 at perforated areas (such as perforated tabs ) so that the buttress material is easily freed from securements 7 on the apparatus.
  • the pivoting first portion bends out of the plane of the apparatus in at least one direction to separate the buttress material 3 at designated areas to prepare for application.
  • the pivoting portion (first portion 4 of the body) of the apparatus is shown as a rectangular shaped portion, however, it is to be understood that other suitable shapes such as rods, loops, wires, rigid meshes, thin strip members, or other shapes may be desired.
  • Figure 1 also illustrates the body formed with an open central region 8. The open central region 8 may be incorporated into the body for ease of movement of the stapler with respect to the body.
  • the buttress material 3 is in contact with at least an area of the pivotable portion 4 of said body 2.
  • Buttress material 3 suitable for use with the present invention can be fabricated from any material having acceptable biocompatibility and mechanical properties.
  • the buttress material 3 may be formed of any suitable material and may be either synthetic or animal-derived. While synthetic materials are preferred due to, for example, their ability to be formed thinly as described herein and for other manufacturing benefits, animal-derived buttress materials may also be used.
  • the buttress material 3 may be a single piece which is wrapped around the body of the apparatus, as shown in Figure 1 , or may be multiple pieces.
  • Animal-derived buttress materials (such as, for example, bovine, porcine, equine, and human products) may have difficulties associated with their placement on the working surfaces (for example the anvil and cartridge jaw surfaces) of surgical staplers. Animal-derived buttress materials cannot typically reach the consistent and thin profiles while maintaining the required strength associated with preferred synthetic buttress materials.
  • An advantage of the present invention is that unlike traditional applications cards which do not allow successful placement of thin buttress materials, a buttress material 3 having a thickness less than 0.5 millimeters may be accurately and successfully positioned onto the working surfaces of a surgical stapler using the present apparatus.
  • animal-derived buttress materials routinely use added steps to apply or actuate adhesives to the outer surface of their materials. For instance, some products utilize rehydration techniques, while others utilize paste-like or gel-type adhesives which need to be applied and smoothed onto the buttress material 3 prior to use. Paste- like or gel-type adhesives allow for sliding of the buttress materials on the working surfaces of a surgical stapler during loading.
  • the present invention does not require added application or actuation steps when a ready to use adhesive such as a pressure sensitive adhesive is employed.
  • a pressure sensitive adhesive can be ready to use by simple removal of a release liner.
  • An unexpected advantage of the present apparatus is that thinner buttress materials such as synthetic non-animal derived materials and other materials particularly those less than 0.5 millimeters in thickness are more readily applied to a stapler working surfaces than is possible with traditional applicator means.
  • the buttress material 3 is able to be readily adhered or placed back to the crotch of a surgical stapler and successfully cover the staple lines with the present apparatus, because the body can be made thin enough to reach to the crotch of a stapler. This ease of placement also allows the buttress material 3 to be attached onto the working surfaces of a stapler without bunching.
  • suitable synthetic buttress materials include but are not limited to: bioabsorbable or biodegradable materials or webs, non- bioabsorbable materials or webs, expanded polytetrafluoroethylene (“ePTFE") such as disclosed in U.S. Patent 5,810,855, synthetic materials, or other suitable buttress materials.
  • ePTFE expanded polytetrafluoroethylene
  • One advantage of using synthetic buttress materials is that there is no need to rehydrate synthetic materials prior to use, and they will have a more consistent thickness.
  • the surgical buttress material 3 may further comprise an adhesive on at least the outermost surface relative to the body of the apparatus.
  • the adhesive may be a ready to use adhesive such as a pressure sensitive adhesive or further may be an activatible adhesive which may be moistened or otherwise activated prior to use.
  • a release liner such as PET release films, or other coated webs or sheets may be applied over an adhesive to protect it until it is ready for use.
  • the release liner may be utilized to cover the buttress material 3 and pre-applied adhesive so that the liner may readily separate from the adhesive on the surgical buttress material 3, thus maintaining the integrity of the adhesive, and allowing it to be easily prepared for use.
  • One advantage of the present apparatus is that the adhesive may be pre-applied and essentially be uniformly distributed over the buttress material. Thus, eliminating the need for any smoothing or spreading as required by unevenly distributed gel or paste- like adhesives traditionally used on buttress materials (see Example 10).
  • the apparatus 1 is sized to apply surgical buttress material 3 onto a surgical stapler.
  • the apparatus may comprise the same material throughout the body or may comprise two or more different materials, such as, but not limited to plastics, metals, cardboards, foams, or any other suitable materials.
  • the apparatus 1 further comprises one or more securements 7 for temporarily fixing buttress material 3 to the apparatus 1.
  • Buttress material 3 is temporarily affixed to the apparatus via this securement to allow the buttress material 3 to extend to about at least a section of the first portion 4 of the body.
  • one securement is simply an affixed tab with a perforated section formed of additional buttress material 3.
  • the optional post is shown as additional securement means.
  • the securements 7 are further illustrated in Figures 3A, 3B, and 4 as comprising a plurality of posts on each body positioned parallel to each other near the pivotable first portion 4 of the body.
  • the posts may be designed to provide tension on the buttress material 3 so that the buttress material 3 is stretched flat, with reduced bunching or wrinkling and provide a more even contact surface to adhere onto a stapler arm. It is to be understood that the posts can be positioned non-parallel to each other in alternate embodiments. These posts are sized and positioned on the bodies to fit perforations in the surgical buttress material 3. Other forms of securement 7 include tabs with adhesive bonding, frictional interference, ultrasonic or thermal welding, mechanical attachments, or any other suitable means of securing the buttress material to the body.
  • the apparatus of the present invention may further comprise a touch-up pad 5.
  • Figure 4 illustrates a touch-up pad 5 which may be permanently or removably attached to the apparatus as an interconnected element.
  • Figure 3A shows an embodiment of the present apparatus which allows the body of the apparatus to be reversibly inserted into a surgical stapler and perform in either inserted configuration.
  • the reversible embodiment of the apparatus comprises a body having a first side 40 and a second side 50 which may be fed into a stapler irrespective of which side is in contact with the anvil and which side is in contact with the cartridge of the stapler.
  • an optional touch-up pad 5 may be permanently or non-permanently attached to the body of the apparatus on one or both sides.
  • the touch-up pad is used to maximize the surface area contact between the buttress material 3 and the working surface of the stapler.
  • adhesive 6 on the outermost facing portion of buttress material 3 adheres the buttress material 3 onto opposed working surfaces of a surgical stapler. After the buttress material is oriented onto the apparatus, it is sometimes desired that the buttress material be further pressed onto a touch pad to adhere the buttress material onto a larger surface area of the stapler.
  • the touch-up pad 5 may be of a uniform or non-uniform topography, further the touch-up pad may comprise of one or multiple pieces, it may be designed as a wedge (for example, Figure 5A) , flat pad (for example, Figure 5B), raised dots( for example, Figure 5C), or the like. It is sometimes desirable that the touch-up pad have specific formations targeted to enhance the surface area around the staple line.
  • the touch-up pad is generally a material such as, but not limited to cottons, polyesters, foams, plastics, metals, or any other suitable materials. It is an advantage to have the touch up pad located in an area apart from the buttress material 3 so that no added thickness or bulk is associated with the buttress material, or apparatus, during application of the material to the arms of the stapler.
  • the body of the apparatus 1 is shaped to include a finger grip 10 to facilitate gripping of the apparatus during loading of a surgical stapler with surgical buttress material 3.
  • the end of the apparatus proximal to the pivotable first portion 4 of the body further comprises a stapler restraining area 23.
  • the stapler restraining area 23 defines the origin or the receiving area for the buttress material (not shown) on the pivotable portion 4 of the body.
  • the created pivotable portion is formed via the restraining area 23 which is in contact with the crotch of a stapler which allows pivoting of the receiving area of the first portion of the body, with respect to the plane of the second portion of the body, to affix buttress material to a stapler.
  • the buttress material 3 is oriented on the body of the apparatus in order to allow a surgical stapler to clamp onto the apparatus.
  • the adhesive 6 on the buttress material 3 adheres the buttress material 3 onto the opposed working surfaces of the surgical stapler.
  • the adhesive on the apparatus is a pressure sensitive adhesive disposed over the surgical buttress material.
  • a release liner 20 may be utilized to cover the pressure sensitive adhesive and keep the adhesive in a ready to use form for application. Removal of the release liner exposes the pressure sensitive adhesive, thus enabling the practitioner to easily and quickly position the buttress material 3 onto the working surface of a surgical stapler.
  • Figure 6A shows a loaded apparatus 1 with a release liner 20 disposed over the buttress material 3.
  • Figure 6B shows a loaded apparatus 1 where the release liner is removed from the buttress material 3 exposing the adhesive on the buttress material and making it ready to engage with a stapler arm.
  • Figure 6C shows a stapler jaw 90 and the apparatus positioned so that the exposed adhesive on the buttress material will make contact with the working surface of the stapler jaw to adhere the buttress material onto the stapler.
  • Figure 6D shows a stapler jaw 90 clamped onto the apparatus 1 to allow contact between the exposed adhesive on the buttress material and the working surface of the stapler.
  • Figure 6E shows a the first portion 4 of the body pivoting out of the plane of the second portion of the body so that the stapler jaw 90 engaged with the first portion 4 moves to break the buttress material 3 at perforated areas and free the buttress material from securements 7 on the apparatus.
  • Other optional features can be added to the body including color coding of the body for ease of loading; measurement ticking, non-slip portions, or other desirable variations. Ergonomic features are also within the skill of one in the art to apply to the present apparatus such as, finger holds, curved surfaces, ribs or other raised features for additional tactile feel or grip ease especially with surgical gloves.
  • the apparatus of the present invention provides a simple method for applying buttress material 3 to a variety of staplers.
  • the body of the apparatus is pre-loaded with buttress material 3 either by an artisan or as purchased in a ready to use embodiment.
  • pre-loaded it is meant that the buttress material 3 is attached to at least a portion of the body which is pivotable with respect to a second portion of said body.
  • the release liner is removed from the buttress material, exposing the adhesive on the exposed surface of the buttress material.
  • the apparatus 1 is then inserted between open stapler arms and aligned with a stapler arm so that the buttress material 3 is in position to be applied to the arms of the stapler upon contact there between.
  • the stapler arms are closed upon the pivotable portion of the body housing the buttress material, the pivotable region of the body is moved away from the plane of the remainder of the body so that the perforated tabs of the buttress material 3 are broken. If desired the touch-up pad may be utilized to maximize the surface area of the buttress material adhered to the stapler arms.
  • the stapler arms are then opened to complete the transfer of the buttress material 3 to the stapler arms.
  • the body of the apparatus is then removed from the stapler arms and discarded and the stapler is ready for use.
  • a 30 mil (0.076 cm) thick card forming the body of the apparatus was made by injection molding polycarbonate and configured to aid in applying surgical staple line buttress (SLR) material to the jaws of a commercially available stapler.
  • the SLR receiving area, stapler restraining area and the pivot of the SLR card were created through a three-sided cutout (S1xS2xS3) of the polycarbonate card using a razor tool.
  • the lengths of the longitudinal cuts (S1 & S3) on the card are about ⁇ 50% of the polycarbonate card (approximately 4.7 cm) and starting approximately 0.6 cm from one end of the card.
  • the length of the latitudinal cut (S2) is sized to accommodate the width of the SLR and jaws of a commercially available stapler (approximately 1 cm).
  • the receiving area is defined by the three sides of the S1 , S2 and S3 cuts.
  • the uncut side of the receiving area defines the pivot.
  • the end of the card closest to the pivot is the stapler restraining area.
  • the restraining area defines the origin or the receiving area. The created pivot allows pivoting of the SLR receiving area with respect to the plane of the polycarbonate card.
  • Example 2 One piece of SLR material with one side having a pressure sensitive adhesive (PSA) with a release liner for covering the PSA is placed on the receiving area of the polycarbonate card prepared as in Example 1.
  • PSA pressure sensitive adhesive
  • the SLR material is precut with connected perforated tabs that extend beyond the width of the receiving area.
  • the SLR material is adapted to fit onto the receiving area and can be attached to the polycarbonate card on each side with perforated tabs that extend past the width of the receiving area.
  • the perforated tabs of the SLR are attached to the polycarbonate card using a second PSA on the opposite side of the first PSA liner.
  • the SLR is attached to the polycarbonate card prior to packaging.
  • the release liner covering the PSA is peeled back and removed.
  • the stapler is positioned against the restraining area of the card and then clamped over the polycarbonate card receiving area on the SLR with the PSA exposed adhesive. This securely attaches the stapler to the SLR.
  • the card is moved perpendicularly to the stapler jaws at the opposing end of the restraining area to break the SLR from the perforated tabs. This releases the SLR from the card and allows the SLR to transfer completely to the stapler.
  • a 30 mil (0.076 cm) thick card (dimension 10.5cm L x 3cm W) was made by injection molding polypropylene and configured to aid in applying SLR material to the jaws of a commercially available stapler.
  • the injection molded card was designed to incorporate the SLR receiving area, stapler restraining area, and the pivot (as in example 1) in the mold design. Additionally, deformable posts were included in the design.
  • a receding section (dimension 2.7 cm L x 1.2 cm W) is included in the design of the card such that the recession is adjacent to the restraining area on the opposite side of the receiving area.
  • the receding section assists docking and positioning of the stapler jaws on the receiving area.
  • a precut SLR material (as in Example 2) with perforated tabs was adapted with holes to fit over the deformable posts. After positioning the SLR material onto the receiving area of the card, and positioning the perforated tabs over the deformable posts, the deformable posts were thermally deformed to capture the tabs and secure the SLR material to the card. Ultrasonic energy was used to thermally deform the posts.
  • the card is moved perpendicularly to the stapler jaws at the opposing end of the restraining area to break the SLR from the perforated tabs. This releases the SLR from the card and allows the SLR to transfer completely to the stapler.
  • Example 6 A card with similar dimensions to Example 5 was created using stereolithography apparatus (SLA). The design of this card was modified to better adapt the card to a surgical stapler by creating a receiving area that is thicker at the distal end of the card than at the proximal end of the card. Additionally the receding section of the card was modified to allow the card and precut SLR material to be positioned within the crotch of the stapler and cover all cartridge and anvil holes.
  • SLA stereolithography apparatus
  • the card per example 6 was further modified to include a touch up pad, 2.5" x .5" x 0.04" (I x w x thickness), made from the same material as the precut SLR.
  • comparative Example 8 highlights the concept that a thin plastic application card of the present invention is preferable to a necessarily thicker application device that includes a foam receiving area.
  • Comparative Example 9 highlights the concept that a thin synthetic buttress material fabricated with a uniform adhesive coating as in an embodiment of the present invention has desirable characteristics as compared to an application device such as that described in U.S. Patent No. 5,752,965, which applies an adhesive gel or the like that requires a foam-type resilient equalization means to establish a uniform adhesion.
  • Comparative Example 8 The card per example 5 was modified by adding a 0.2" rib around the card for ergonomic ease. Addition of the rib made the card less flexible. This change also provided the card with additional stiffness to aid deployment, especially while pivoting the card.
  • a card comprised of a foam receiving area (approximately 0.125" thickness) was constructed and a precut SLR material and a pressure sensitive adhesive was attached to the foam via clips.
  • the SLR was then positioned onto a surgical stapler in the same manner as in Example 4. Upon positioning the SLR into the stapler, the thickness of the foam card caused the SLR material to prematurely touch the stapler causing the SLR material to bunch and not cover the entire staple line.
  • Paul MN was modified by replacing the foam pad with a 0.035" thick polypropylene card.
  • the supplied adhesive (Synovis, Part # 7300- 101023, St. Paul MN) was then added in a continuous bead to the SLR material, per instructions for use, and the assembly was positioned within the working surface of the stapler jaws.
  • the supplied adhesive was gel- like in nature, and required pressure to evenly distribute the adhesive onto the material.
  • the stapler (Ethicon, Proximate 75, Cincinnati OH) was then closed and then re-opened to examine the deployment of the SLR onto the stapler jaws.
  • the specification may have presented the method and/or process of the present invention as a particular sequence of steps. However, to the extent that the method or process does not rely on the particular order of steps set forth herein, the method or process should not be limited to the particular sequence of steps described. As one of ordinary skill in the art would appreciate, other sequences of steps may be possible. Therefore, the particular order of the steps set forth in the specification should not be construed as limitations on the claims. In addition, the claims directed to the method and/or process of the present invention should not be limited to the performance of their steps in the order written, and one skilled in the art can readily appreciate that the sequences may be varied and still remain within the spirit and scope of the present invention.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
PCT/US2008/011610 2007-10-08 2008-10-08 Apparatus for supplying surgical staple line reinforcement Ceased WO2009048589A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2010528883A JP5426558B2 (ja) 2007-10-08 2008-10-08 外科用ステープルラインの補強材を供給するための装置
AU2008311321A AU2008311321B2 (en) 2007-10-08 2008-10-08 Apparatus for supplying surgical staple line reinforcement
HK10111396.5A HK1144767B (en) 2007-10-08 2008-10-08 Apparatus for supplying surgical staple line reinforcement
EP08836898.0A EP2205164B1 (en) 2007-10-08 2008-10-08 Apparatus for supplying surgical staple line reinforcement
ES08836898T ES2426767T3 (es) 2007-10-08 2008-10-08 Aparato para suministrar un refuerzo de líneas de grapas quirúrgicas
CA2702033A CA2702033C (en) 2007-10-08 2008-10-08 Apparatus for supplying surgical staple line reinforcement

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97817807P 2007-10-08 2007-10-08
US60/978,178 2007-10-08

Publications (1)

Publication Number Publication Date
WO2009048589A1 true WO2009048589A1 (en) 2009-04-16

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/011610 Ceased WO2009048589A1 (en) 2007-10-08 2008-10-08 Apparatus for supplying surgical staple line reinforcement

Country Status (7)

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US (1) US8453904B2 (enExample)
EP (1) EP2205164B1 (enExample)
JP (1) JP5426558B2 (enExample)
AU (1) AU2008311321B2 (enExample)
CA (1) CA2702033C (enExample)
ES (1) ES2426767T3 (enExample)
WO (1) WO2009048589A1 (enExample)

Cited By (1)

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CN110432942A (zh) * 2018-05-04 2019-11-12 北京博辉瑞进生物科技有限公司 一种吻合口加固修补组合件

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CA2702033C (en) 2013-11-26
AU2008311321A1 (en) 2009-04-16
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JP5426558B2 (ja) 2014-02-26
CA2702033A1 (en) 2009-04-16

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