WO2009022722A1 - 3環系アミン化合物 - Google Patents
3環系アミン化合物 Download PDFInfo
- Publication number
- WO2009022722A1 WO2009022722A1 PCT/JP2008/064577 JP2008064577W WO2009022722A1 WO 2009022722 A1 WO2009022722 A1 WO 2009022722A1 JP 2008064577 W JP2008064577 W JP 2008064577W WO 2009022722 A1 WO2009022722 A1 WO 2009022722A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hydrogen atom
- alkyl group
- amine compound
- group
- tricyclic amine
- Prior art date
Links
- -1 amine compound Chemical class 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 150000004492 retinoid derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/28—Phenalenes; Hydrogenated phenalenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/34—Benzoheptalenes; Hydrogenated benzoheptalenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2008287819A AU2008287819A1 (en) | 2007-08-15 | 2008-08-14 | Tricyclic amine compound |
CA2695984A CA2695984A1 (en) | 2007-08-15 | 2008-08-14 | Tricyclic amine compound |
US12/673,221 US8143260B2 (en) | 2007-08-15 | 2008-08-14 | Tricyclic amine compound |
CN2008801113601A CN101821229B (zh) | 2007-08-15 | 2008-08-14 | 三环类胺化合物 |
EP08792458A EP2189440A1 (en) | 2007-08-15 | 2008-08-14 | Tricyclic amine compound |
EA201070274A EA201070274A1 (ru) | 2007-08-15 | 2008-08-14 | Трициклическое аминное соединение |
JP2009528147A JP5399249B2 (ja) | 2007-08-15 | 2008-08-14 | 3環系アミン化合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007211651 | 2007-08-15 | ||
JP2007-211651 | 2007-08-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009022722A1 true WO2009022722A1 (ja) | 2009-02-19 |
Family
ID=40350775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/064577 WO2009022722A1 (ja) | 2007-08-15 | 2008-08-14 | 3環系アミン化合物 |
Country Status (9)
Country | Link |
---|---|
US (1) | US8143260B2 (ja) |
EP (1) | EP2189440A1 (ja) |
JP (1) | JP5399249B2 (ja) |
CN (1) | CN101821229B (ja) |
AU (1) | AU2008287819A1 (ja) |
CA (1) | CA2695984A1 (ja) |
EA (1) | EA201070274A1 (ja) |
TW (1) | TW200927709A (ja) |
WO (1) | WO2009022722A1 (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2758041B1 (de) | 2011-09-20 | 2021-01-13 | Basf Se | Niedermolekulare modulatoren des kälte-menthol-rezeptors trpm8 und deren verwendung |
WO2020157069A1 (en) * | 2019-01-28 | 2020-08-06 | NodThera Limited | Amino heterocyclic compounds and uses thereof |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6122047A (ja) | 1984-07-07 | 1986-01-30 | Koichi Shiyudo | 安息香酸誘導体 |
JPS6176440A (ja) | 1984-09-19 | 1986-04-18 | Koichi Shiyudo | 安息香酸誘導体 |
JPH0344348A (ja) * | 1989-06-30 | 1991-02-26 | Firmenich Sa | 新規芳香族化合物、その製法、該化合物を含有する賦香組成物または香料添加製品、ならびに芳香特性を改良、強調または変更する方法および該化合物の中間体 |
JPH0971566A (ja) | 1995-06-30 | 1997-03-18 | Eisai Co Ltd | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
WO1997011061A1 (fr) | 1995-09-21 | 1997-03-27 | Nikken Chemicals Co., Ltd. | Composes a potentialisation de retinoide |
JPH1059951A (ja) | 1995-09-21 | 1998-03-03 | Iyaku Bunshi Sekkei Kenkyusho:Kk | レチノイド作用増強性化合物 |
WO1999024415A1 (fr) | 1997-11-12 | 1999-05-20 | Institute Of Medicinal Molecular Design, Inc. | Agonistes du recepteur du retinoide |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5442124A (en) | 1989-06-30 | 1995-08-15 | Firmenich Sa | Process for the preparation of novel aromatic compounds |
US5185318A (en) | 1989-06-30 | 1993-02-09 | Firmenich S.A. | Aromatic compounds, a process for preparation thereof and use of same as perfuming ingredients |
JP3044348B1 (ja) | 1998-12-28 | 2000-05-22 | 株式会社大阪冷研 | プリフォ―ム口首部の内径規制用コア |
-
2008
- 2008-08-14 EA EA201070274A patent/EA201070274A1/ru unknown
- 2008-08-14 TW TW097130991A patent/TW200927709A/zh unknown
- 2008-08-14 AU AU2008287819A patent/AU2008287819A1/en not_active Abandoned
- 2008-08-14 CA CA2695984A patent/CA2695984A1/en not_active Abandoned
- 2008-08-14 CN CN2008801113601A patent/CN101821229B/zh not_active Expired - Fee Related
- 2008-08-14 US US12/673,221 patent/US8143260B2/en not_active Expired - Fee Related
- 2008-08-14 EP EP08792458A patent/EP2189440A1/en not_active Withdrawn
- 2008-08-14 JP JP2009528147A patent/JP5399249B2/ja not_active Expired - Fee Related
- 2008-08-14 WO PCT/JP2008/064577 patent/WO2009022722A1/ja active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6122047A (ja) | 1984-07-07 | 1986-01-30 | Koichi Shiyudo | 安息香酸誘導体 |
JPS6176440A (ja) | 1984-09-19 | 1986-04-18 | Koichi Shiyudo | 安息香酸誘導体 |
JPH0344348A (ja) * | 1989-06-30 | 1991-02-26 | Firmenich Sa | 新規芳香族化合物、その製法、該化合物を含有する賦香組成物または香料添加製品、ならびに芳香特性を改良、強調または変更する方法および該化合物の中間体 |
JPH0971566A (ja) | 1995-06-30 | 1997-03-18 | Eisai Co Ltd | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
WO1997011061A1 (fr) | 1995-09-21 | 1997-03-27 | Nikken Chemicals Co., Ltd. | Composes a potentialisation de retinoide |
JPH1059951A (ja) | 1995-09-21 | 1998-03-03 | Iyaku Bunshi Sekkei Kenkyusho:Kk | レチノイド作用増強性化合物 |
WO1999024415A1 (fr) | 1997-11-12 | 1999-05-20 | Institute Of Medicinal Molecular Design, Inc. | Agonistes du recepteur du retinoide |
Non-Patent Citations (11)
Title |
---|
ADV. DRUG RES., vol. 24, 1993, pages 81 |
BIOCHEM. BIOPHYS. RES. COM., vol. 166, 1990, pages 1300 |
CELL STRUCTURE FUNCT., vol. 16, 1991, pages 113 |
DAVIDSON J.P. ET AL.: "First Enantiospecific Total Synthesis of the Antitubercular Marine Natural Product Pseudopteroxazole. Revision of Assigned Stereochemistry", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 125, no. 44, 2003, pages 13486 - 13489, XP008131575 * |
EKLUND L. ET AL.: "Synthetic studies towards pseudopterosin A", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1: ORGANIC AND BIO-ORGANIC CHEMISTRY, no. 4, 1996, pages 303 - 305 * |
EVANS, R.M., SCIENCE, vol. 240, 1988, pages 889 |
J. MED. CHEM., vol. 48, 2005, pages 5875 |
JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, no. 11, 1988, pages 2182 |
MANGELSDORF, D.J. ET AL., NATURE, vol. 345, pages 224 - 229 |
MANGELSDORF, D.J. ET AL.: "The Retinoids", 1994, RAVAN PRESS, pages: 319 - 350 |
PIERS E. ET AL.: "Synthesis of functionalized hexahydro-, octahydro-, and decahydro-1H-phenalenes via Diels-Alder reactions of 1-methylene-4a-methoxycarbonyl-1,2,3,4,4a,5,6,7-octahydronap thalene and related dienes", CANADIAN JOURNAL OF CHEMISTRY, vol. 71, no. 9, 1993, pages 1463 - 1483, XP008131573 * |
Also Published As
Publication number | Publication date |
---|---|
CN101821229B (zh) | 2013-06-05 |
US20110288299A1 (en) | 2011-11-24 |
CA2695984A1 (en) | 2009-02-19 |
US8143260B2 (en) | 2012-03-27 |
JP5399249B2 (ja) | 2014-01-29 |
TW200927709A (en) | 2009-07-01 |
CN101821229A (zh) | 2010-09-01 |
AU2008287819A1 (en) | 2009-02-19 |
EP2189440A1 (en) | 2010-05-26 |
EA201070274A1 (ru) | 2010-10-29 |
JPWO2009022722A1 (ja) | 2010-11-18 |
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